Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domainzf-C2H2_6

ZNF675 ZNF182 GZF1 ZNF473 ZNF570 ZNF652 ZNF615 ZNF236

2.75e-05314728PF13912
DomainSerum_albumin/AFP/Afamin

AFM ALB

4.39e-053722IPR021177
DomainALBUMIN

AFM ALB

8.75e-054722SM00103
DomainSerum_albumin_N

AFM ALB

8.75e-054722IPR014760
DomainALBUMIN_1

AFM ALB

8.75e-054722PS00212
DomainSerum_albumin_CS

AFM ALB

8.75e-054722IPR020857
DomainSerum_albumin

AFM ALB

8.75e-054722PF00273
DomainALBUMIN_2

AFM ALB

8.75e-054722PS51438
DomainSerum_albumin-like

AFM ALB

1.45e-045722IPR020858
DomainALB/AFP/VDB

AFM ALB

2.18e-046722IPR000264
DomainRecF/RecN/SMC_N

SMC5 SMC1B

4.04e-048722IPR003395
DomainSMC_N

SMC5 SMC1B

4.04e-048722PF02463
DomainZINC_FINGER_C2H2_1

ZNF675 ZNF182 TUT4 GZF1 ZNF473 ZNF570 ZNF652 ZBTB40 ZNF615 ZNF236

7.61e-047777210PS00028
Domain-

ZNF675 ZNF182 GZF1 ZNF473 ZNF570 ZNF652 ZBTB40 ZNF615 ZNF236

1.16e-036797293.30.160.60
Domainzf-C2H2

ZNF675 ZNF182 GZF1 ZNF473 ZNF570 ZNF652 ZBTB40 ZNF615 ZNF236

1.33e-03693729PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF675 ZNF182 GZF1 ZNF473 ZNF570 ZNF652 ZBTB40 ZNF615 ZNF236

1.35e-03694729IPR013087
DomainC1_1

CDC42BPA DEF8 VAV3

1.38e-0357723PF00130
DomainZF_DAG_PE_1

CDC42BPA DEF8 VAV3

1.93e-0364723PS00479
DomainZF_DAG_PE_2

CDC42BPA DEF8 VAV3

1.93e-0364723PS50081
DomainC1

CDC42BPA DEF8 VAV3

2.02e-0365723SM00109
DomainPE/DAG-bd

CDC42BPA DEF8 VAV3

2.11e-0366723IPR002219
DomainPLAC

ADAMTS12 PCSK5

2.40e-0319722PS50900
DomainPLAC

ADAMTS12 PCSK5

2.40e-0319722IPR010909
DomainEGF-like_dom

PCSK5 PRF1 MATN3 CRB1 PROS1

2.74e-03249725IPR000742
DomainZINC_FINGER_C2H2_2

ZNF675 ZNF182 GZF1 ZNF473 ZNF570 ZNF652 ZBTB40 ZNF615 ZNF236

2.86e-03775729PS50157
DomainGrowth_fac_rcpt_

PCSK5 MATN3 CRB1 PROS1

3.10e-03156724IPR009030
DomainZnf_C2H2-like

ZNF675 ZNF182 GZF1 ZNF473 ZNF570 ZNF652 ZBTB40 ZNF615 ZNF236

3.41e-03796729IPR015880
DomainZnf_C2H2

ZNF675 ZNF182 GZF1 ZNF473 ZNF570 ZNF652 ZBTB40 ZNF615 ZNF236

3.67e-03805729IPR007087
DomainZnF_C2H2

ZNF675 ZNF182 GZF1 ZNF473 ZNF570 ZNF652 ZBTB40 ZNF615 ZNF236

3.76e-03808729SM00355
DomainPH_dom-like

PTK2B CDC42BPA DCP1B VAV3 FGD6 LYST

5.98e-03426726IPR011993
Pubmed

Dual Requirement of Cytokine and Activation Receptor Triggering for Cytotoxic Control of Murine Cytomegalovirus by NK Cells.

IL18 PRF1 LYST

3.45e-061475326720279
Pubmed

The role and molecular mechanism of metabolic reprogramming of colorectal cancer by UBR5 through PYK2 regulation of OXPHOS expression study.

PTK2B UBR5

4.59e-06275237098808
Pubmed

Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.

PRF1 LYST

4.59e-06275221878672
Pubmed

Liganded ERα Stimulates the E3 Ubiquitin Ligase Activity of UBE3C to Facilitate Cell Proliferation.

ZNF182 PPP2R3A USP16

9.10e-061975326389696
Pubmed

Interleukin-7 receptor expression on CD8 T-cells is downregulated by the HIV Tat protein.

PRF1 IL7R

1.37e-05375216967044
Pubmed

Alpha-fetoprotein related gene (ARG): a new member of the albumin gene family that is no longer functional in primates.

AFM ALB

1.37e-05375219733224
Pubmed

Clinical presentation and outcome of pediatric patients with hemophagocytic lymphohistiocytosis in China: A retrospective multicenter study.

PRF1 LYST

1.37e-05375227781387
Pubmed

Interleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha.

PTK2B IL7R

1.37e-05375210702271
Pubmed

Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility.

AFM ALB

1.37e-05375212297623
Pubmed

Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis.

PRF1 LYST

1.37e-05375232419134
Pubmed

The evolution of SMC proteins: phylogenetic analysis and structural implications.

SMC5 SMC1B

2.75e-05475214660695
Pubmed

Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress.

ATF3 ALB

2.75e-05475231907991
Pubmed

Inflammation in atherosclerosis: lesion formation in LDL receptor-deficient mice with perforin and Lyst(beige) mutations.

PRF1 LYST

2.75e-05475212171798
Pubmed

Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway.

PTK2B SEMA4D

4.57e-05575216055703
Pubmed

Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium.

PRF1 LYST

4.57e-05575222617213
Pubmed

Identification and Evaluation of New Immunoregulatory Genes in Mesenchymal Stromal Cells of Different Origins: Comparison of Normal and Inflammatory Conditions.

SEMA4D FGL2

4.57e-05575228336906
Pubmed

Perforin is a critical physiologic regulator of T-cell activation.

PRF1 LYST

4.57e-05575221606480
Pubmed

Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer.

IL18 PRF1

4.57e-05575215967825
Pubmed

Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively.

IL18 PRF1

4.57e-05575210395644
Pubmed

Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect.

PRF1 LYST

6.84e-05675238722309
Pubmed

Suppression of lymphoma and epithelial malignancies effected by interferon gamma.

IL18 PRF1

6.84e-05675212093877
Pubmed

NK-cell-mediated killing of target cells triggers robust antigen-specific T-cell-mediated and humoral responses.

IL18 PRF1

9.57e-05775219406986
Pubmed

Humanized mice in translational biomedical research.

PRF1 LYST

9.57e-05775217259968
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PTK2B CDC42BPA DCP1B DTL ANKRD11 FGD6 LYST WNK3 GOLGB1

9.77e-0586175936931259
Pubmed

IFN-γ production by lung NK cells is critical for the natural resistance to pulmonary metastasis of B16 melanoma in mice.

IL18 PRF1

1.27e-04875221712396
Pubmed

Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes.

SYNPO2 AKAP4

1.27e-04875217923693
Pubmed

Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage.

PRF1 ALB

1.27e-04875226588782
Pubmed

Predisposition for TMPRSS2-ERG fusion in prostate cancer by variants in DNA repair genes.

POLI SMC5

1.64e-04975219861517
Pubmed

An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection.

IL18 PRF1

2.04e-041075227341123
Pubmed

Immune effectors required for hepatitis B virus clearance.

PRF1 LYST

2.04e-041075220080755
Pubmed

Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

PRF1 LYST

2.04e-041075217982459
Pubmed

Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner.

PLVAP IL7R

2.49e-041175218403646
Pubmed

The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion.

SEMA4D RTN4

2.49e-041175214534257
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

PPP2R3A CDC42BPA UBR5 SYTL4 CNTRL ALB GOLGB1 CRB1

2.70e-0477775835844135
Pubmed

Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase.

PLVAP IL7R

2.99e-041275220208005
Pubmed

Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium.

IL18 PRF1

3.52e-041375226572063
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

CNTRL UTP20 RAB13 GOLGB1 ITPR2

3.86e-0428575532838362
Pubmed

LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.

PLVAP IL7R

4.11e-041475219380791
Pubmed

The human plasma proteome: a nonredundant list developed by combination of four separate sources.

IL18 ALB GOLGB1 PROS1

4.57e-0416575414718574
Pubmed

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.

SPINT2 MBTPS2 ATF3 WDR76 ITPR2

4.58e-0429675534186245
Pubmed

Common body mass index-associated variants confer risk of extreme obesity.

PRF1 RTN4

4.73e-041575219553259
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ZNF182 ZNF473 ZNF652 CNTRL DTL DEF8 ZBTB40 LETM1 GOLGB1

5.34e-04108475911544199
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

MBTPS2 UBR5 DTL MIB1 ANKRD11 ZBTB40 C10orf90 ZNF236 SMC5 USP16

5.50e-041327751032694731
Pubmed

The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC.

GTF3C1 POLR3E

6.11e-04177521403646
Pubmed

Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin.

ALB GOLGB1

6.11e-041775221795745
Pubmed

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis.

UBR5 SYTL4

6.87e-041875232924931
Pubmed

IL-2 and IL-15 regulate CD8+ memory T-cell differentiation but are dispensable for protective recall responses.

PRF1 IL7R

6.87e-041875226426795
Pubmed

A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis.

PLVAP GFRA1

7.66e-041975234686326
Pubmed

Lymph sacs are not required for the initiation of lymph node formation.

PLVAP IL7R

7.66e-041975219060331
Pubmed

Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β.

IL18 IL7R

7.66e-041975230937919
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

CDC42BPA RTN4 DEF8 LYST GOLGB1 ITPR2

7.78e-0450475634432599
Pubmed

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.

VAV3 ZNF236 FGD6

8.38e-048575323648065
Pubmed

The LIFEdb database in 2006.

PCSK5 RBM22 SYNPO2 RTN4 HPF1 POLI RAB13

9.29e-0472075716381901
Pubmed

Temporal and spatial transcriptional programs in murine kidney development.

RTN4 ALB

9.38e-042175215998744
Pubmed

From ORFeome to biology: a functional genomics pipeline.

PCSK5 RBM22 SYNPO2 RTN4 HPF1 POLI RAB13

9.44e-0472275715489336
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

RBM22 TUT4 SYTL4 RTN4 EXOC1 SMC5 USP16

9.59e-0472475736232890
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ADAMTS12 PCSK5 PTK2B SEMA4D TUT4 CDC42BPA WNK3

1.01e-0373075734857952
Pubmed

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation.

UTP20 QRSL1

1.03e-032275230951662
Pubmed

Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation.

PLVAP ALB

1.03e-032275235293576
Pubmed

Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor.

IL18 PRF1

1.23e-032475234526512
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

ADAMTS12 CRB1

1.23e-032475232212159
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ADAMTS12 CDC42BPA ZNF652 RAD54B ZBTB40 LYST

1.24e-0355275610737800
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CDC42BPA UBR5 RTN4 MIB1 ANKRD11 USP16 QRSL1 LETM1 GOLGB1 ITPR2

1.31e-031487751033957083
Pubmed

An unappreciated role for RNA surveillance.

ATF3 LYST GFRA1

1.42e-0310275314759258
Pubmed

DNA cloning using in vitro site-specific recombination.

PCSK5 RBM22 SYNPO2 RTN4 HPF1 POLI RAB13

1.63e-0379475711076863
Pubmed

Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.

UBR5 MIB1

1.67e-032875235474067
Pubmed

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.

DTL WDR76

1.67e-032875217041588
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

TUT4 UBR5 ALB WNK3

1.70e-0323575430258100
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SEMA4D RBM22 DCAF6 ZNF473 HPF1 MIB1 DEF8 EXOC1 USP16

1.76e-03128575935914814
Pubmed

Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.

ANKRD11 ALB

1.92e-033075211483580
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PWWP2A GTF3C1 ZNF570 RAD54B ZBTB40 WDR76

2.02e-0360875636089195
Pubmed

Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.

PTK2B ITPR2

2.05e-033175214684825
Pubmed

Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.

UBR5 RTN4 ALB

2.05e-0311675330652415
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

UBR5 DTL ZBTB40

2.05e-0311675330804394
InteractionCRB1 interactions

MIB1 ALB CRB1

1.02e-0512743int:CRB1
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF675 ZNF182 GZF1 ZNF473 ZNF570 ZNF652 ZBTB40 ZNF615 ZNF236

1.15e-0471849928
GeneFamilyStructural maintenance of chromosomes proteins|Cohesin complex

SMC5 SMC1B

1.50e-047492761
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF6 DTL

1.07e-0318492498
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HMGL

PTK2B IL18 PLVAP SPINT2 ATF3 LYST RAB13 IL7R FGL2 ITPR2

5.01e-065777410M39051
CoexpressionGSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_UP

PTK2B SEMA4D IL18 PRF1 PROS1 FGL2

1.03e-05175746M6684
CoexpressionGSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN

PCSK5 PPP2R3A IL18 SPINT2 ALB FGL2

2.14e-05199746M8352
CoexpressionGSE17721_PAM3CSK4_VS_CPG_2H_BMDC_DN

NARF RBM22 IL18 CDC42BPA FGD6 FGL2

2.20e-05200746M3858
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPINT2 CNTRL HPF1 DTL CNTLN SMC5 WDR76 LYST

1.02e-0918775814c239af77116d28d511dea754b6150d20488080
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 CNTRL ANKRD11 ATF3 LYST IL7R

6.87e-071847561154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 CNTRL VAV3 ATF3 LYST GFRA1

7.09e-071857567adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

CDC42BPA CNTRL ANKRD11 USP16 GOLGB1 PROS1

1.08e-0619975661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTK2B SEMA4D CCDC168 FGL2 ITPR2

4.22e-06142755f720f13b339589fa924a42e89393e5db0b26300b
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 CNTRL ATF3 LYST GFRA1

1.41e-05182755f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 SYNPO2 DTL RAD54B WDR76

1.60e-05187755e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 SYNPO2 DTL RAD54B WDR76

1.60e-05187755cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D PLVAP SPINT2 LYST ITPR2

1.69e-051897558e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

PWWP2A GTF3C1 PRF1 VAV3 FGL2

1.69e-05189755fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

PWWP2A GTF3C1 PRF1 VAV3 FGL2

1.69e-05189755b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTRL ANKRD11 SMC5 GOLGB1 ITPR2

1.77e-0519175560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTRL ANKRD11 SMC5 GOLGB1 ITPR2

1.77e-05191755973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellILEUM-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SYNPO2 DCAF6 LYST RAB13 IL7R

1.87e-05193755d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL18 SPINT2 ATF3 RAB13 FGL2

2.11e-05198755c1fe38594bd6292fcc60bdbb563376b454731d00
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CDC42BPA CNTRL ANKRD11 USP16 GOLGB1

2.11e-0519875576d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18 SPINT2 ATF3 RAB13 FGL2

2.11e-05198755bfc15de70a7577a2860b53e1e6826a7b5ad23040
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

DTL RAD54B CCDC168 WDR76 RAB13

2.16e-05199755e222b90caf45904d8f763574e7b6aac13333df92
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

CDC42BPA CNTRL ANKRD11 USP16 GOLGB1

2.16e-05199755fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GTF3C1 PRF1 ZNF652 GOLGB1 IL7R

2.16e-05199755cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TUT4 UBR5 DTL FGD6 IL7R

2.21e-05200755dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 SYNPO2 ZNF473 DCP1B ATF3

2.21e-05200755a372ef3f9e6ff6e3c3376d6e10182977c5067788
ToppCellBronchus_Control_(B.)-Immune-TX-DCs|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

PLVAP GZF1 IL7R FGL2 ITPR2

2.21e-05200755e0beacb88bbdc353a3e883171613027feafcf1ef
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 SYTL4 DTL QRSL1

7.32e-051327544152529611eeacf0c547e2a134d5b98c45426b13
ToppCellsevere_influenza-NK_CD56bright|World / disease group, cell group and cell class (v2)

SYNPO2 PRF1 MIB1 CCDC168

1.33e-04154754187b9d4eb0e98c506034735601ead480ff00bd57
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 TRIML1 SYNPO2 GFRA1

1.50e-04159754e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA4D DTL RAD54B WDR76

1.50e-0415975495128a2367ff2a639b21913c0350924c174faef8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 TRIML1 SYNPO2 GFRA1

1.50e-041597542607b562903228274fbd96168ba826782fab0b53
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(Neuron.Gad1Gad2.Sst-Nr2f2)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTTG1IP2 OC90 CRB1

1.57e-04627539db88da996b9977f5a89afe505cd55e7b5324bc9
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(Neuron.Gad1Gad2.Sst-Nr2f2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTTG1IP2 OC90 CRB1

1.57e-0462753461d280a1b955033186cfc326f9ace85b4a53c54
ToppCelldroplet-Heart-4Chambers|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP SPINT2 ALB FGL2

1.61e-041627545625ec6dae204d5537883f05ea546970628d10bb
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLI ZBTB40 LYST ITPR2

1.69e-04164754950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLI ZBTB40 LYST ITPR2

1.69e-04164754c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCelldroplet-Liver-nan-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLI ZBTB40 LYST ITPR2

1.69e-04164754bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP DTL WDR76 PROS1

1.73e-041657546a621b300442c52adfc15b61d3a6d3a3cb00099f
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCP1B RAD54B POLI IL7R

1.81e-04167754754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DTL WDR76 IL7R FGL2

1.81e-0416775453e32d6687a07f486141df9f4ab998af4c03a507
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DTL RAD54B WDR76 IL7R

1.85e-04168754ade02beb8d663fce4be2aefa10392ab849a4bbe7
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEF8 CCDC168 WNK3 FGL2

1.85e-04168754a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 SYNPO2 DTL GFRA1

1.90e-04169754a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 SYNPO2 GFRA1 ITPR2

1.94e-0417075484d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4D GTF3C1 PRF1 IL7R

1.94e-04170754059f7ae615342ea19f43b0a405cd7272251a78a9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 SYNPO2 DTL WDR76

1.98e-04171754b0373ed8283ee1792b6a490bff93906546978593
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SEMA4D TUT4 GOLGB1 IL7R

1.98e-041717542e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 PCSK5 SYNPO2 GFRA1

1.98e-041717545d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 SYNPO2 DTL WDR76

1.98e-04171754b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellfacs-Heart-RV-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D SPINT2 PRF1 IL7R

1.98e-04171754dbffd55db0b3fc6eeb38d05189d84653f0111b31
ToppCellfacs-Heart-RV-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D SPINT2 PRF1 IL7R

1.98e-04171754eee1199332c09aaae021134ee7c91661b11df50a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 SYNPO2 GFRA1 ITPR2

2.03e-04172754cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 CDC42BPA VAV3 FGL2

2.07e-04173754e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCellfacs-Large_Intestine-Proximal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 CDC42BPA VAV3 FGL2

2.07e-0417375499532bb768ee35fed939a377acb5215d3f8904bd
ToppCellILEUM-inflamed-(1)_T_(gd)|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SEMA4D PRF1 VAV3 IL7R

2.07e-0417375485c3e227c81c6ab70148639381389fba3ac5e088
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP DTL RAD54B WDR76

2.12e-04174754c988471207ba06195bc3e41056435e8c31c20bbe
ToppCelldroplet-Heart-4Chambers-21m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP SPINT2 ALB FGL2

2.12e-04174754f098778ea74012861ec74b425e45776a31f67679
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP SYTL4 RAD54B WNK3

2.12e-041747546c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 PLVAP SYTL4 GFRA1

2.21e-041767547292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 TRPC7 GFRA1 IL7R

2.21e-04176754ed7ba2a3af3b060dec98b60f09f96000a67f7e63
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 PLVAP SYTL4 GFRA1

2.21e-0417675488ca2f83d8301633232735f39b0683efe49d0b86
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP DTL RAD54B WDR76

2.26e-041777548a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

ADAMTS12 PCSK5 RTN4 ITPR2

2.31e-04178754278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GTF3C1 HPF1 LYST IL7R

2.31e-041787540290868dc990878eac5c182fe64968333bc52450
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DTL CNTLN WDR76 RAB13

2.36e-04179754e1bfd553c043ebc070ccf8545d489ba16d9b2ef4
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP4 SPINT2 PRF1 IL7R

2.36e-041797548bf04a7ad1b0be6722ebfdceba3f083f07bf96c5
ToppCellVE-matDC|VE / Condition, Cell_class and T cell subcluster

SYNPO2 ATF3 CNTLN RAB13

2.46e-04181754982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ADAMTS12 SYNPO2 MATN3 GFRA1

2.46e-0418175435c470988a93381eefa300831aabb813fa1b90bd
ToppCellVE-matDC-|VE / Condition, Cell_class and T cell subcluster

SYNPO2 ATF3 CNTLN RAB13

2.46e-041817546252184ef098b911df50be4fe1b5565849a5b6b8
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 SMC5 LYST IL7R

2.52e-04182754e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 SMC5 LYST IL7R

2.52e-041827541710eab3037a87609d21838be2d2d29c3bc36651
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 PCSK5 SYNPO2 GFRA1

2.57e-0418375412daaea821e49bc94a01e2496331e92a80d27339
ToppCellILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ZNF652 ATF3 GOLGB1 IL7R

2.62e-04184754cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NARF PRF1 VAV3 IL7R

2.68e-041857543a046c948524e5d0e986cd645e318d6930d7e0ee
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 PCSK5 SYNPO2 CNTLN

2.68e-041857546712512100ccef456d2e2bd201d0987986c92ac9
ToppCellfacs-Marrow-T-cells-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 PRF1 ALB IL7R

2.68e-04185754e1fd0a807def8c2127194108b1a30c6de7024292
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NARF PRF1 VAV3 IL7R

2.68e-0418575471d1a771026d9fa3528d46ac3d11353e396f2d87
ToppCellMild-CD4+_T|Mild / Disease group and Cell class

SPINT2 CCDC62 IL7R PROS1

2.68e-04185754c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VAV3 CCDC168 FGD6 ITPR2

2.68e-041857545a0340c25196453f19e424d346efbf66d2c53ac3
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTK2B SPINT2 RTN4 DTL

2.73e-0418675456c139e679d640ea901ead657a8e8887e0fca098
ToppCellILEUM-inflamed-(1)_T_cell-(1)_Cytotoxic_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GTF3C1 PRF1 ATF3 LYST

2.85e-04188754c80956649b10b7dd7540394a00fc2a0619b27e80
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 DCAF6 UBR5 IL7R

2.85e-041887546468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 DCAF6 UBR5 IL7R

2.85e-041887547a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 DCAF6 UBR5 IL7R

2.85e-041887549cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellILEUM-inflamed-(1)_Cytotoxic_CD8_Trm|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GTF3C1 PRF1 LYST IL7R

2.85e-04188754d26894d1066a70e4b32ae41fff1c4718f2591ba9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 RTN4 ATF3 FGL2

2.85e-0418875436459e5b91cbd7336a502d96b0dc37ca560ae4d6
ToppCellP28-Endothelial-large_vessel_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PCSK5 PTK2B PLVAP FGL2

2.85e-04188754263169029293e005bcffd87db20221fdd2d3917e
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ANKRD11 ATF3 GOLGB1 IL7R

2.90e-041897542c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D PLVAP SPINT2 LYST

2.90e-04189754fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-MAIT|lymph-node_spleen / Manually curated celltypes from each tissue

GTF3C1 PRF1 ATF3 IL7R

2.90e-04189754afe3a4fe7c10eeeb7064129778d940269c9acbef
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUT4 POLR3E GOLGB1 IL7R

2.96e-0419075491ba66d4b56c59523485b17738e93f14bb00afa4
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IL18 SPINT2 RTN4 FGL2

2.96e-041907544b25d49f033bbd326b47cf5602af3f0262cfc367
ToppCellControl-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

GTF3C1 PRF1 VAV3 LYST

2.96e-041907541584c68b58c7f406d9b0e8451beea3e6f8980c56
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

PTK2B SEMA4D PRF1 IL7R

2.96e-04190754e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

PCSK5 ZNF652 LYST ITPR2

3.02e-04191754ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IL18 SPINT2 RTN4 FGL2

3.08e-041927548e606eae3e5b07a856d3c2a74186d486da96309c
ToppCell367C-Myeloid-Dendritic-cDC2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

IL18 SPINT2 ATF3 FGL2

3.14e-04193754940e9a419d0de1f9e72b5cc9c86684057003be58
ToppCell367C-Myeloid-Dendritic|367C / Donor, Lineage, Cell class and subclass (all cells)

IL18 SPINT2 ATF3 FGL2

3.14e-04193754365e831ae6ac67fb36d8d70ef139f4ae7e32c83f
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

TUT4 UBR5 GOLGB1 ITPR2

3.14e-04193754e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell10x5'-Lung-Myeloid_Dendritic-DC2|Lung / Manually curated celltypes from each tissue

IL18 PLVAP SPINT2 FGL2

3.14e-04193754c97f9b13057f803df63c696c6175ef8e0aba6fa7
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SPINT2 SYTL4 RTN4 PROS1

3.14e-041937543d4411b3c1cb160dec5db29f0c126d8827dfe185
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PCSK5 GTF3C1 PRF1 ANKRD11

3.21e-041947546be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCell368C-Myeloid-Dendritic-cDC2|368C / Donor, Lineage, Cell class and subclass (all cells)

IL18 SPINT2 ATF3 FGL2

3.21e-04194754eb9656d6d2da9aa074e6f5c06d750a6f9828208a
DrugAC1NCGO2

AKAP4 PRF1 LYST

9.21e-0613743CID004558605
Drugperfluoropentane

PRF1 ALB

3.12e-053742CID000012675
DrugMeticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A

CDC42BPA PRF1 RAD54B WDR76 LYST GFRA1

3.83e-051927461792_UP
Drugtroglitazone; Up 200; 10uM; MCF7; HT_HG-U133A

PPP2R3A CDC42BPA PRF1 ATF3 LYST QRSL1

3.94e-051937461657_UP
DrugNafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

TUT4 MBTPS2 ZNF473 ZNF652 CNTRL WDR76

4.17e-051957463323_DN
DrugCefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; HL60; HT_HG-U133A

CDC42BPA ZNF473 ANKRD11 ZBTB40 UTP20 LYST

4.17e-051957466159_DN
DrugGlyoxal

IL18 ATF3 ALB

4.20e-0521743ctd:D006037
DrugMethacholine chloride [62-51-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A

PPP2R3A CDC42BPA ZNF473 CNTRL RAD54B LETM1

4.29e-051967463452_DN
Drugrofecoxib; Down 200; 10uM; HL60; HG-U133A

PLVAP GTF3C1 MBTPS2 ANKRD11 ZBTB40 ITPR2

4.42e-05197746371_DN
Drugaspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A

PPP2R3A CNTRL RAD54B ZBTB40 WDR76 GOLGB1

4.42e-051977465564_DN
DrugNorgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A

ZNF675 SEMA4D PPP2R3A ZNF652 FGD6 LETM1

4.42e-051977463406_DN
DrugMonensin sodium salt [22373-78-0]; Down 200; 5.8uM; MCF7; HT_HG-U133A

ZNF675 PPP2R3A ZNF652 ZBTB40 WDR76 LETM1

4.42e-051977463443_DN
DrugMoxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

SEMA4D ZBTB40 SMC5 FGD6 LYST IL7R

4.67e-051997461804_UP
DiseaseLymphoma, non-Hodgkin, familial

PRF1 RAD54B

5.68e-055712cv:C4721532
DiseaseNon-Hodgkin lymphoma

PRF1 RAD54B

5.68e-055712cv:C0024305
DiseaseLYMPHOMA, NON-HODGKIN, FAMILIAL

PRF1 RAD54B

5.68e-055712605027
DiseaseLiver Cirrhosis, Experimental

IL18 AFM RTN4 ATF3 ALB SMC5 GFRA1 IL7R FGL2

9.78e-05774719C0023893
Diseasealcoholic hepatitis (is_marker_for)

IL18 ALB

1.58e-048712DOID:12351 (is_marker_for)
Diseaseautoimmune thrombocytopenic purpura (is_marker_for)

IL18 ALB

4.38e-0413712DOID:8924 (is_marker_for)
Diseasebiliary atresia (is_marker_for)

IL18 SPINT2

5.10e-0414712DOID:13608 (is_marker_for)
Diseasetrimethylamine-N-oxide measurement

RTN4 ITPR2

5.10e-0414712EFO_0010541
Diseasesquamous cell carcinoma

ADAMTS12 DEF8 ANKRD11

5.73e-0467713EFO_0000707
DiseaseUrticaria

IL18 ALB

6.70e-0416712C0042109
Diseaselung non-small cell carcinoma (is_marker_for)

IL18 UBR5 ALB IL7R

7.48e-04169714DOID:3908 (is_marker_for)
Diseasenon-Hodgkin lymphoma (is_implicated_in)

PRF1 RAD54B

7.58e-0417712DOID:0060060 (is_implicated_in)
Diseaseskin sensitivity to sun

ADAMTS12 ANKRD11

9.51e-0419712EFO_0004795
DiseaseLow Grade Lymphoma (neoplasm)

PRF1 RAD54B

1.16e-0321712C0079747
DiseaseLymphoma, Intermediate-Grade

PRF1 RAD54B

1.16e-0321712C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

PRF1 RAD54B

1.16e-0321712C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

PRF1 RAD54B

1.16e-0321712C0079757
DiseaseLymphoma, Undifferentiated

PRF1 RAD54B

1.16e-0321712C0024306
DiseaseReticulosarcoma

PRF1 RAD54B

1.16e-0321712C0024302
DiseaseLymphoma, Mixed-Cell

PRF1 RAD54B

1.16e-0321712C0024304
DiseaseLymphoma, Diffuse

PRF1 RAD54B

1.16e-0321712C3714542
DiseaseLymphoma, Non-Hodgkin, Familial

PRF1 RAD54B

1.28e-0322712C4721532
DiseaseLymphoma, Small Noncleaved-Cell

PRF1 RAD54B

1.28e-0322712C0079770
DiseaseCFTR mutation carrier status

PCSK5 VAV3

1.65e-0325712EFO_0021794
Diseaseputamen volume change measurement, age at assessment

VAV3 IL7R

1.93e-0327712EFO_0008007, EFO_0021495
Diseasesuntan

DEF8 ANKRD11 CRB1

1.99e-03103713EFO_0004279
Diseasepneumonia (is_marker_for)

IL18 ALB

2.07e-0328712DOID:552 (is_marker_for)
Diseaseantipsychotic drug use measurement

PWWP2A ZNF473

2.22e-0329712EFO_0007792
Diseaselongevity, healthspan, parental longevity

DEF8 FGD6

2.22e-0329712EFO_0004300, EFO_0007796, EFO_0009762

Protein segments in the cluster

PeptideGeneStartEntry
CTKEKTKNAVEKFTD

CNTRL

1451

Q7Z7A1
NQDSISSKLKECCEK

ALB

291

P02768
SILEKCQKDKEFDKC

ANKRD11

1041

Q6UB99
NRSDKSSCDECKEKK

CCDC62

366

Q6P9F0
SSCDECKEKKQQIDT

CCDC62

371

Q6P9F0
KDKSQEIKDTKECVQ

CNTLN

216

Q9NXG0
CKVATKACSNKDEKG

AKAP4

516

Q5JQC9
KQDSISSKIKECCEK

AFM

291

P43652
SSKIKECCEKKIPER

AFM

296

P43652
EKKKSNFKCSICEKA

GZF1

311

Q9H116
TRIKTSCTKEDCKDD

DCAF6

171

Q58WW2
DSSCLESVKQKCVKS

DTL

556

Q9NZJ0
CKKSADLLCTKDKLS

ADAMTS12

1531

P58397
SIKEKECSSTCDKNE

RAD54B

601

Q9Y620
STDLKTCDKKNTNKC

RAB13

186

P51153
KKTEVCQTCSKLKNV

RBM22

66

Q9NW64
KQKKEEILKTTCFIC

ITPR2

2551

Q14571
QCEKTTDVKKSKFCE

HPF1

16

Q9NWY4
LNADKKTCSVRDKCA

MATN3

381

O15232
ACSKLQEQKKSLTKE

LETM1

551

O95202
DTKKNLCRKCSENCK

PCSK5

731

Q92824
EIAKEKTICTKDKES

PLVAP

171

Q9BX97
SISAEAKACEEKKKK

PRF1

271

P14222
NICVKVGEKSLTCKK

IL7R

106

P16871
KCCLKLSVKITSSKN

DEFB116

66

Q30KQ4
TEVNCVSKKIICESK

OC90

141

Q02509
CTDIIKQCIKKKSGS

PPP2R3A

246

Q06190
TKIEECVVCSDKKAA

MIB1

861

Q86YT6
AVKKSCQLCTEDKKC

PTTG1IP2

51

P0DTF9
IKAKDEYTKCKTCSE

DCP1B

166

Q8IZD4
CLIDCNEKTRKKSQK

ERVK-24

111

P63145
CIIDCNEKTRKKSQK

HERVK_113

111

P62684
KASDQCLKEQSCSTK

GFRA1

31

P56159
TELCQKCLSLIKKTK

QRSL1

21

Q9H0R6
AKCRNKKKEKTECLQ

ATF3

101

P18847
KIKKAACNICTVDSD

LYST

631

Q99698
EATQVCRTNKDCKKS

MBTPS2

366

O43462
KSKSVKQTCDKCNTI

DEF8

206

Q6ZN54
KEIVNSLKKSCQDCK

FGL2

86

Q14314
KKKKNCFLCATVTTE

EXOC1

31

Q9NV70
ENVKSTQKTQTDCKC

CCDC168

1261

Q8NDH2
KINVAVKTCKKDCTL

PTK2B

451

Q14289
VKTCKKDCTLDNKEK

PTK2B

456

Q14289
TLIDDSCKEKCIAKA

CRB1

581

P82279
SVKCEKISTLSCENK

IL18

101

Q14116
DSFKKCSSEVEAKNK

POLI

331

Q9UNA4
SKQEVDKVLKDCCVS

POLR3E

681

Q9NVU0
KIESNLESKVDKKCF

RTN4

411

Q9NQC3
RCKVCAKEIELKKAT

SYTL4

101

Q96C24
KVTKTNCCESSEQIK

UTP20

306

O75691
LCDKCKNSVVAEKKE

PWWP2A

321

Q96N64
KCAEKGKSKQTECLN

SEMA4D

96

Q92854
SNIITECKLKDSEKK

CDC42BPA

906

Q5VT25
KKDCKDVDECSLKPS

PROS1

196

P07225
CCDLVVKIKECKKSE

C10orf90

516

Q96M02
ECTECDKTFLKKSQL

ZNF615

261

Q8N8J6
CNECKKTFSDKSTLI

ZNF182

376

P17025
NICQDCKTDNKVKDK

USP16

46

Q9Y5T5
EKQVKEAKSKCKSIA

SYNPO2

366

Q9UMS6
KKSIKDSEKQCSKQE

SMC1B

316

Q8NDV3
KEECLKKCATVTENA

SPINT2

81

O43291
VEKCTKPCKDSTKKN

FGD6

611

Q6ZV73
KCEECEKAVNQSSKL

ZNF675

201

Q8TD23
KERVKLCQEETKTCK

TRIML1

161

Q8N9V2
NNEVACKKTKIKKTC

WDR76

76

Q9H967
VCAEKKLLKCNDCEK

ZNF570

211

Q96NI8
KACKKEFETSSELKE

ZNF236

156

Q9UL36
LQLKKGCESVDKCKV

ZNF66

111

Q6ZN08
KQEGVSTKCCKKSIV

GTF3C1

646

Q12789
KAKCEEKETLTCEKC

ZNF652

236

Q9Y2D9
EKATDIKEASQKCKQ

SMC5

326

Q8IY18
NDICIEKTEVKSCKV

TUT4

61

Q5TAX3
EKCKCKTLIAGQKSA

UBR5

1236

O95071
AKSKQVQCKECSETK

ZBTB40

761

Q9NUA8
VQCKECSETKDSKKE

ZBTB40

766

Q9NUA8
KLCKSKAKSCENDLE

TRPC7

731

Q9HCX4
EQKEKCFKCNKCEKT

ZNF473

556

Q8WTR7
SKTKEDVKLKLEECS

VAV3

296

Q9UKW4
KSTSEISKDCFKEKN

WNK3

111

Q9BYP7
KENKEYSEKCVTSKC

GOLGB1

1041

Q14789
CTRKECSKKTKTDDQ

NARF

6

Q9UHQ1