Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RGPD8 RGPD3 RGPD1

1.64e-0720504GO:0061665
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RGPD8 RGPD3 RGPD1

1.93e-0636504GO:0019789
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RGPD8 RGPD3 RGPD1

7.36e-0650504GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RGPD8 RGPD3 RGPD1

9.30e-0653504GO:0016859
GeneOntologyMolecularFunctionextracellular matrix structural constituent

THSD4 TFPI2 SPOCK2 ECM1 MUC5AC

1.05e-04188505GO:0005201
GeneOntologyMolecularFunctionisomerase activity

RGPD4 RGPD8 RGPD3 RGPD1 ALOX15

1.16e-04192505GO:0016853
GeneOntologyMolecularFunctionfrizzled binding

FZD1 WNT8A WNT8B

1.58e-0442503GO:0005109
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM1 GRM6

2.19e-049502GO:0098988
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM1 GRM6

2.19e-049502GO:0001640
GeneOntologyMolecularFunctiongamma-catenin binding

APC2 APC

3.99e-0412502GO:0045295
GeneOntologyMolecularFunctionGTPase activator activity

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

6.51e-04279505GO:0005096
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 RGPD8 PLEKHG4 RGPD3 RGPD1 RGPD5

1.60e-03507506GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 RGPD8 PLEKHG4 RGPD3 RGPD1 RGPD5

1.60e-03507506GO:0030695
GeneOntologyMolecularFunctionglutamate receptor activity

GRM1 GRM6

2.07e-0327502GO:0008066
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RGPD4 RGPD8 RGPD3 RGPD1 TRIM39

3.11e-03398505GO:0061659
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.14e-0920515GO:0006607
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RGPD8 RGPD3 RGPD1

4.14e-099514GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RGPD8 RGPD3 RGPD1

6.89e-0910514GO:1903301
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RGPD8 RGPD3 RGPD1

2.33e-0813514GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RGPD8 RGPD3 RGPD1

3.26e-0814514GO:1903299
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RGPD8 RGPD3 RGPD1

2.30e-0638514GO:0000413
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RGPD8 RGPD3 RGPD1

9.57e-0654514GO:0018208
GeneOntologyBiologicalProcessregulation of gluconeogenesis

RGPD4 RGPD8 RGPD3 RGPD1

2.85e-0571514GO:0006111
GeneOntologyBiologicalProcessmRNA transport

RGPD4 RGPD8 RGPD3 RGPD1 NXT2

2.90e-05145515GO:0051028
GeneOntologyBiologicalProcessRNA transport

RGPD4 RGPD8 RGPD3 RGPD1 NXT2

7.11e-05175515GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

RGPD4 RGPD8 RGPD3 RGPD1 NXT2

7.11e-05175515GO:0050657
GeneOntologyBiologicalProcessestablishment of RNA localization

RGPD4 RGPD8 RGPD3 RGPD1 NXT2

7.71e-05178515GO:0051236
GeneOntologyBiologicalProcessnuclear export

RGPD4 RGPD8 RGPD3 RGPD1 NXT2

9.25e-05185515GO:0051168
GeneOntologyBiologicalProcessprotein import into nucleus

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.18e-04195515GO:0006606
GeneOntologyBiologicalProcessimport into nucleus

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.36e-04201515GO:0051170
GeneOntologyBiologicalProcessgluconeogenesis

RGPD4 RGPD8 RGPD3 RGPD1

1.63e-04111514GO:0006094
GeneOntologyBiologicalProcesshexose biosynthetic process

RGPD4 RGPD8 RGPD3 RGPD1

1.87e-04115514GO:0019319
GeneOntologyBiologicalProcessRNA localization

RGPD4 RGPD8 RGPD3 RGPD1 NXT2

1.95e-04217515GO:0006403
GeneOntologyBiologicalProcesscanonical Wnt signaling pathway

FZD1 FOLR1 WNT8A WNT8B APC2 APC

1.97e-04344516GO:0060070
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

GRM1 GRM6

2.13e-049512GO:0007196
GeneOntologyBiologicalProcessmonosaccharide biosynthetic process

RGPD4 RGPD8 RGPD3 RGPD1

2.28e-04121514GO:0046364
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

RGPD4 RGPD8 RGPD3 RGPD1

3.17e-04132514GO:0043255
GeneOntologyBiologicalProcessnuclear transport

RGPD4 RGPD8 RGPD3 RGPD1 NXT2 RGPD5

3.27e-04378516GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

RGPD4 RGPD8 RGPD3 RGPD1 NXT2 RGPD5

3.27e-04378516GO:0006913
GeneOntologyBiologicalProcessregulation of glucose metabolic process

RGPD4 RGPD8 RGPD3 RGPD1

3.36e-04134514GO:0010906
GeneOntologyBiologicalProcesscarbohydrate biosynthetic process

RGPD4 RGPD8 RGPD3 RGPD1 FUT3

3.54e-04247515GO:0016051
GeneOntologyBiologicalProcessnucleobase-containing compound transport

RGPD4 RGPD8 RGPD3 RGPD1 NXT2

3.68e-04249515GO:0015931
GeneOntologyBiologicalProcesspositive regulation of kinase activity

RGPD4 RGPD8 NTRK3 RGPD3 TLR3 RGPD1

4.71e-04405516GO:0033674
GeneOntologyBiologicalProcesscell junction assembly

FZD1 NTRK3 CLDN16 APC SPOCK2 LRTM2 GRM6

4.73e-04569517GO:0034329
GeneOntologyBiologicalProcessG protein-coupled glutamate receptor signaling pathway

GRM1 GRM6

7.04e-0416512GO:0007216
GeneOntologyBiologicalProcesssynapse assembly

FZD1 NTRK3 SPOCK2 LRTM2 GRM6

9.62e-04308515GO:0007416
GeneOntologyBiologicalProcessregulation of establishment of planar polarity

FZD1 PKHD1

9.98e-0419512GO:0090175
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD8 RGPD3 RGPD1

2.18e-098514GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD8 RGPD3 RGPD1

6.53e-0910514GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RGPD8 RGPD3 RGPD1

3.09e-0814514GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RGPD8 RGPD3 RGPD1

9.37e-0818514GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RGPD8 RGPD3 RGPD1

1.48e-0720514GO:0042405
GeneOntologyCellularComponentnuclear pore

RGPD4 RGPD8 RGPD3 RGPD1 NXT2 RGPD5

1.65e-07101516GO:0005643
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RGPD8 RGPD3 RGPD1

1.82e-0721514GO:0106068
GeneOntologyCellularComponentinclusion body

RGPD4 KLF8 RGPD8 RGPD3 RGPD1

2.66e-0690515GO:0016234
GeneOntologyCellularComponentextracellular matrix

THSD4 TFPI2 WNT8A TLR3 SPOCK2 MUC5B ECM1 MUC5AC

1.74e-04656518GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

THSD4 TFPI2 WNT8A TLR3 SPOCK2 MUC5B ECM1 MUC5AC

1.78e-04658518GO:0030312
GeneOntologyCellularComponentnuclear envelope

RGPD4 RGPD8 RGPD3 RGPD1 APC NXT2 RGPD5

3.97e-04560517GO:0005635
GeneOntologyCellularComponentbeta-catenin destruction complex

APC2 APC

4.47e-0413512GO:0030877
GeneOntologyCellularComponentWnt signalosome

FZD1 APC

6.85e-0416512GO:1990909
GeneOntologyCellularComponentlamellipodium membrane

FAP APC2

1.31e-0322512GO:0031258
GeneOntologyCellularComponentnuclear membrane

RGPD4 RGPD8 RGPD3 RGPD1 APC

1.58e-03349515GO:0031965
GeneOntologyCellularComponentperinuclear region of cytoplasm

RGPD4 RGPD8 RGPD3 APC2 RGPD1 PKHD1 APC NXT2

1.78e-03934518GO:0048471
GeneOntologyCellularComponentcatenin complex

APC2 APC

2.76e-0332512GO:0016342
GeneOntologyCellularComponentcytoplasmic microtubule

CFAP95 APC2 APC

4.20e-03133513GO:0005881
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RGPD8 RGPD3 RGPD1

9.19e-0816394MP:0003701
MousePhenoaneuploidy

RGPD4 RGPD8 RGPD3 RGPD1 APC

6.88e-0761395MP:0004024
MousePhenoabnormal morula morphology

RGPD4 RGPD8 RGPD3 RGPD1

7.40e-0726394MP:0012058
MousePhenodecreased tumor latency

RGPD4 RGPD8 RGPD3 RGPD1

1.35e-0630394MP:0010308
MousePhenoincreased hepatocellular carcinoma incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC

1.37e-0670395MP:0003331
MousePhenofailure of blastocyst formation

RGPD4 RGPD8 RGPD3 RGPD1

1.54e-0631394MP:0012129
MousePhenoabnormal tumor latency

RGPD4 RGPD8 RGPD3 RGPD1

2.26e-0634394MP:0010307
MousePhenoincreased incidence of tumors by chemical induction

RGPD4 RGPD8 FOLR1 RGPD3 RGPD1 APC

2.35e-06141396MP:0004499
MousePhenoabnormal chromosome number

RGPD4 RGPD8 RGPD3 RGPD1 APC

3.83e-0686395MP:0004023
MousePhenoabnormal blastocyst formation

RGPD4 RGPD8 RGPD3 RGPD1

3.97e-0639394MP:0012128
MousePhenoincreased incidence of induced tumors

RGPD4 RGPD8 FOLR1 RGPD3 RGPD1 APC

7.66e-06173396MP:0002021
MousePhenoincreased sarcoma incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC

8.86e-06102395MP:0002032
MousePhenoincreased tumor incidence

RGPD4 RGPD8 FOLR1 RGPD3 TLR3 RGPD1 APC GRM1 ALOX15

1.16e-05530399MP:0002020
MousePhenoincreased liver tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC

1.34e-05111395MP:0008019
MousePhenoincreased hepatobiliary system tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC

1.34e-05111395MP:0010297
MousePhenoabnormal rod electrophysiology

RGPD4 RGPD8 RGPD3 RGPD1 GRM6

1.88e-05119395MP:0004021
MousePhenoabnormal chromosome morphology

RGPD4 RGPD8 RGPD3 RGPD1 APC

2.47e-05126395MP:0003702
MousePhenoabnormal mitosis

RGPD4 RGPD8 RGPD3 RGPD1 PKHD1

2.67e-05128395MP:0004046
MousePhenoneoplasm

RGPD4 RGPD8 FOLR1 RGPD3 TLR3 RGPD1 APC GRM1 WDFY4 ALOX15

2.76e-057473910MP:0002006
MousePhenoincreased malignant tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC GRM1

4.55e-05237396MP:0002018
MousePhenoabnormal tumor incidence

RGPD4 RGPD8 FOLR1 RGPD3 TLR3 RGPD1 APC GRM1 ALOX15

4.84e-05635399MP:0002019
MousePhenoabnormal tumor susceptibility

RGPD4 RGPD8 FOLR1 RGPD3 TLR3 RGPD1 APC GRM1 ALOX15

5.81e-05650399MP:0002166
MousePhenoincreased lung carcinoma incidence

RGPD4 RGPD8 RGPD3 RGPD1

6.36e-0578394MP:0008714
MousePhenoincreased classified tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC GRM1 ALOX15

7.66e-05381397MP:0010273
MousePhenoabnormal classified tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC GRM1 ALOX15

8.04e-05384397MP:0020188
MousePhenoabnormal incidence of induced tumors

RGPD4 RGPD8 FOLR1 RGPD3 RGPD1 APC

9.19e-05269396MP:0013151
MousePhenoincreased organ/body region tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC GRM1 ALOX15

9.60e-05395397MP:0010274
MousePhenoabnormal organ/body region tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC GRM1 ALOX15

1.05e-04401397MP:0013152
MousePhenoincreased physiological sensitivity to xenobiotic

RGPD4 RGPD8 FOLR1 RGPD3 RGPD1 APC

1.29e-04286396MP:0008873
MousePhenoabnormal cell nucleus morphology

RGPD4 RGPD8 RGPD3 RGPD1 APC

1.50e-04184395MP:0003111
MousePhenoincreased susceptibility to infection induced morbidity/mortality

USP18 TFPI2 TLR3 MUC5B CLEC4M

1.54e-04185395MP:0009787
MousePhenoenlarged epididymis

RGPD4 RGPD8 RGPD3 RGPD1

1.61e-0499394MP:0004931
MousePhenoincreased susceptibility to bacterial infection induced morbidity/mortality

USP18 TFPI2 MUC5B CLEC4M

1.81e-04102394MP:0009788
MousePhenoincreased carcinoma incidence

RGPD4 RGPD8 RGPD3 RGPD1 APC

2.06e-04197395MP:0002038
MousePhenoincreased lung tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1

2.17e-04107394MP:0008014
MousePhenofailure of blastocyst to hatch from the zona pellucida

RGPD4 RGPD8 RGPD3 RGPD1

2.17e-04107394MP:0003694
MousePhenoincreased respiratory system tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1

2.17e-04107394MP:0010298
MousePhenoabnormal blastocyst hatching

RGPD4 RGPD8 RGPD3 RGPD1

2.68e-04113394MP:0003693
MousePhenoabnormal eye electrophysiology

RGPD4 RGPD8 RGPD3 RGPD1 GRM6

4.05e-04228395MP:0005551
MousePhenoabsent forebrain

FOLR1 APC

6.76e-0414392MP:0012136
MousePhenodecreased susceptibility to diet-induced obesity

RGPD4 RGPD8 RGPD3 RGPD1

9.95e-04160394MP:0005659
MousePhenoabnormal susceptibility to infection induced morbidity/mortality

USP18 TFPI2 TLR3 MUC5B CLEC4M

1.01e-03279395MP:0009785
MousePhenoabnormal epididymis size

RGPD4 RGPD8 RGPD3 RGPD1

1.14e-03166394MP:0004926
MousePhenoabnormal preimplantation embryo development

RGPD4 RGPD8 RGPD3 RGPD1

1.27e-03171394MP:0009781
MousePhenoabnormal eye physiology

RGPD4 RGPD8 RGPD3 RGPD1 GRM1 GRM6 MUC5AC

1.27e-03606397MP:0005253
MousePhenodecreased susceptibility to weight gain

RGPD4 RGPD8 RGPD3 RGPD1

1.73e-03186394MP:0010182
MousePhenoabnormal response to novel object

TLR3 LRTM2 GPRASP2

1.81e-0387393MP:0003461
DomainGrip

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

5.66e-1111515SM00755
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

5.66e-1111515PF01465
DomainRan_BP1

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

9.69e-1112515PF00638
DomainGRIP_dom

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

9.69e-1112515IPR000237
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

9.69e-1112515PS50913
DomainRANBD1

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

9.69e-1112515PS50196
DomainRanBD

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.57e-1013515SM00160
DomainRan_bind_dom

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.57e-1013515IPR000156
DomainGCC2_Rab_bind

RGPD4 RGPD8 RGPD3 RGPD1

1.72e-097514IPR032023
DomainRab_bind

RGPD4 RGPD8 RGPD3 RGPD1

1.72e-097514PF16704
Domain-

RGPD4 RGPD8 RGPD3 RGPD1

1.02e-08105141.10.220.60
DomainWnt8

WNT8A WNT8B

7.31e-062512IPR013301
DomainAPC_dom

APC2 APC

7.31e-062512IPR026831
DomainAPC_N

APC2 APC

7.31e-062512IPR032038
DomainAPC_basic_dom

APC2 APC

7.31e-062512IPR009234
DomainApc_fam

APC2 APC

7.31e-062512IPR026818
DomainAPC_r

APC2 APC

7.31e-062512PF05923
DomainSAMP

APC2 APC

7.31e-062512PF05924
DomainAPC_rpt

APC2 APC

7.31e-062512IPR009223
DomainSAMP

APC2 APC

7.31e-062512IPR009224
DomainAPC_basic

APC2 APC

7.31e-062512PF05956
DomainAPC_N_CC

APC2 APC

7.31e-062512PF16689
DomainTPR-contain_dom

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

5.45e-05150515IPR013026
DomainTPR_REGION

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

8.57e-05165515PS50293
DomainTPR

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

8.57e-05165515PS50005
DomainWxxW_domain

MUC5B MUC5AC

1.09e-046512IPR025155
DomainMucin2_WxxW

MUC5B MUC5AC

1.09e-046512PF13330
DomainPH_dom-like

RGPD4 RGPD8 PLEKHG4 RGPD3 RGPD1 WDFY4 RGPD5

1.49e-04426517IPR011993
DomainGPCR_3_mtglu_rcpt

GRM1 GRM6

2.03e-048512IPR000162
DomainTPR

RGPD4 RGPD8 RGPD3 RGPD1

4.22e-04129514SM00028
DomainTPR-like_helical_dom

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

4.26e-04233515IPR011990
DomainTPR_repeat

RGPD4 RGPD8 RGPD3 RGPD1

4.74e-04133514IPR019734
DomainTIL

MUC5B MUC5AC

4.74e-0412512PF01826
DomainC8

MUC5B MUC5AC

4.74e-0412512PF08742
DomainUnchr_dom_Cys-rich

MUC5B MUC5AC

5.59e-0413512IPR014853
DomainNCD3G

GRM1 GRM6

5.59e-0413512PF07562
DomainC8

MUC5B MUC5AC

5.59e-0413512SM00832
DomainGPCR_3_9-Cys_dom

GRM1 GRM6

5.59e-0413512IPR011500
DomainTIL_dom

MUC5B MUC5AC

6.51e-0414512IPR002919
DomainGPCR_3_CS

GRM1 GRM6

6.51e-0414512IPR017979
DomainTSP_1

THSD4 THSD7B C8A

6.79e-0463513PF00090
DomainTSP1

THSD4 THSD7B C8A

7.44e-0465513SM00209
DomainTSP1_rpt

THSD4 THSD7B C8A

7.44e-0465513IPR000884
DomainTSP1

THSD4 THSD7B C8A

7.44e-0465513PS50092
DomainGlyco_hormone_CN

MUC5B MUC5AC

7.50e-0415512IPR006208
DomainCys_knot

MUC5B MUC5AC

7.50e-0415512PF00007
DomainVWD

MUC5B MUC5AC

8.56e-0416512SM00216
DomainVWF_type-D

MUC5B MUC5AC

8.56e-0416512IPR001846
DomainVWFD

MUC5B MUC5AC

8.56e-0416512PS51233
DomainVWD

MUC5B MUC5AC

8.56e-0416512PF00094
DomainLH2

PKD1L2 ALOX15

1.09e-0318512SM00308
DomainCTCK_1

MUC5B MUC5AC

1.09e-0318512PS01185
DomainWnt

WNT8A WNT8B

1.21e-0319512IPR005817
DomainVWC_out

MUC5B MUC5AC

1.21e-0319512SM00215
DomainWnt_CS

WNT8A WNT8B

1.21e-0319512IPR018161
Domainwnt

WNT8A WNT8B

1.21e-0319512PF00110
DomainWNT1

WNT8A WNT8B

1.21e-0319512SM00097
DomainWNT1

WNT8A WNT8B

1.21e-0319512PS00246
DomainGPCR_3

GRM1 GRM6

1.49e-0321512IPR000337
DomainPLAT

PKD1L2 ALOX15

1.49e-0321512PS50095
Domain-

PKD1L2 ALOX15

1.49e-03215122.60.60.20
DomainPLAT

PKD1L2 ALOX15

1.49e-0321512PF01477
DomainPLAT/LH2_dom

PKD1L2 ALOX15

1.49e-0321512IPR001024
Domain7tm_3

GRM1 GRM6

1.63e-0322512PF00003
DomainG_PROTEIN_RECEP_F3_2

GRM1 GRM6

1.63e-0322512PS00980
DomainG_PROTEIN_RECEP_F3_3

GRM1 GRM6

1.63e-0322512PS00981
DomainG_PROTEIN_RECEP_F3_1

GRM1 GRM6

1.63e-0322512PS00979
DomainG_PROTEIN_RECEP_F3_4

GRM1 GRM6

1.63e-0322512PS50259
DomainCT

MUC5B MUC5AC

1.63e-0322512SM00041
DomainGPCR_3_C

GRM1 GRM6

1.63e-0322512IPR017978
DomainCys-rich_flank_reg_C

NTRK3 TLR3 LRTM2

1.91e-0390513IPR000483
DomainTPR_1

RGPD8 RGPD1 RGPD5

1.91e-0390513PF00515
DomainTPR_1

RGPD8 RGPD1 RGPD5

1.91e-0390513IPR001440
DomainLRRCT

NTRK3 TLR3 LRTM2

1.91e-0390513SM00082
DomainCys_knot_C

MUC5B MUC5AC

2.11e-0325512IPR006207
DomainCTCK_2

MUC5B MUC5AC

2.11e-0325512PS01225
DomainLRRNT

NTRK3 TLR3 LRTM2

2.43e-0398513IPR000372
DomainLRRNT

NTRK3 TLR3 LRTM2

2.43e-0398513SM00013
Domain-

RGPD4 RGPD8 RGPD3 RGPD1

2.44e-032075141.25.40.10
DomainVWC

MUC5B MUC5AC

2.64e-0328512PF00093
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RGPD8 RGPD3 RGPD1

1.65e-0718404MM1549
PathwayBIOCARTA_WNT_LRP6_PATHWAY

FZD1 WNT8A WNT8B

4.21e-076403MM1588
PathwayBIOCARTA_WNT_LRP6_PATHWAY

FZD1 WNT8A WNT8B

4.21e-076403M22083
PathwayKEGG_BASAL_CELL_CARCINOMA

FZD1 WNT8A WNT8B APC2 APC

4.45e-0755405M17807
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD1 WNT8A WNT8B APC

1.65e-0631404M27400
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD1 WNT8A WNT8B APC

1.65e-0631404MM15154
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RGPD8 RGPD3 RGPD1

4.72e-0640404MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RGPD8 RGPD3 RGPD1

5.22e-0641404MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

5.75e-0642404MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RGPD8 RGPD3 RGPD1

6.33e-0643404MM14609
PathwayKEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

FZD1 WNT8A WNT8B APC

7.61e-0645404M47412
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY

FZD1 WNT8A WNT8B APC

8.32e-0646404M47409
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

9.08e-0647404MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RGPD8 RGPD3 RGPD1

1.07e-0549404MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RGPD8 RGPD3 RGPD1

1.16e-0550404MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

1.26e-0551404MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RGPD8 RGPD3 RGPD1

1.71e-0555404MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

2.11e-0558404MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RGPD8 RGPD3 RGPD1

2.11e-0558404MM14736
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

3.32e-0565404MM15147
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THSD4 MUC5B THSD7B MUC5AC

3.97e-0568404M27303
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 RGPD8 RGPD3 RGPD1

5.25e-0573404MM14948
PathwayKEGG_WNT_SIGNALING_PATHWAY

FZD1 WNT8A WNT8B APC2 APC

6.42e-05151405M19428
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

THSD4 RGPD4 USP18 FBXW10B FBXW10 RGPD8 FOLR1 RGPD3 RGPD1 APC MUC5B THSD7B MUC5AC

7.37e-0513894013MM15307
PathwayREACTOME_RHO_GTPASE_EFFECTORS

RGPD4 RGPD8 RGPD3 RGPD1 NOX3 ARPC1B

7.90e-05257406MM14755
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 RGPD8 RGPD3 RGPD1

8.29e-0582404MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

9.10e-0584404MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 RGPD8 RGPD3 RGPD1

9.98e-0586404MM15413
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RGPD4 RGPD8 RGPD3 RGPD1

1.30e-0492404MM14951
PathwayKEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

WNT8A WNT8B APC

1.54e-0437403M47411
PathwayREACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES

RGPD4 RGPD8 RGPD3 RGPD1

1.79e-04100404MM14561
PathwayREACTOME_O_LINKED_GLYCOSYLATION

THSD4 MUC5B THSD7B MUC5AC

2.49e-04109404MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

THSD4 MUC5B THSD7B MUC5AC

2.67e-04111404M27416
PathwayREACTOME_MITOTIC_PROPHASE

RGPD4 RGPD8 RGPD3 RGPD1

2.96e-04114404MM15361
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

RGPD4 RGPD8 RGPD3 RGPD1

3.27e-04117404MM15387
PathwayWP_MICROTUBULE_CYTOSKELETON_REGULATION

DPYSL2 NTRK3 APC

3.35e-0448403M39566
PathwayREACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION

RGPD4 RGPD8 RGPD3 RGPD1

4.74e-04129404MM14894
PathwayREACTOME_RHO_GTPASES_ACTIVATE_FORMINS

RGPD4 RGPD8 RGPD3 RGPD1

6.63e-04141404MM15266
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

THSD4 MUC5B THSD7B MUC5AC

6.99e-04143404M27275
PathwayBIOCARTA_PS1_PATHWAY

FZD1 APC

6.99e-0414402MM1459
PathwayBIOCARTA_PS1_PATHWAY

FZD1 APC

6.99e-0414402M16173
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM1 GRM6

8.05e-0415402M39442
PathwayBIOCARTA_PITX2_PATHWAY

FZD1 APC

8.05e-0415402MM1439
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM1 GRM6

8.05e-0415402MM15845
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC5B MUC5AC

9.19e-0416402M27410
PathwayBIOCARTA_PITX2_PATHWAY

FZD1 APC

9.19e-0416402M8516
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

FZD1 WNT8A WNT8B APC

1.01e-03158404MM14791
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC5B MUC5AC

1.04e-0317402M27412
PathwayWP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS

FZD1 APC

1.04e-0317402M39525
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

FZD1 WNT8A WNT8B CLDN16

1.09e-03161404M39770
PathwayREACTOME_SUMOYLATION

RGPD4 RGPD8 RGPD3 RGPD1

1.30e-03169404MM14919
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION

WNT8A WNT8B

1.30e-0319402M47836
PathwayBIOCARTA_GSK3_PATHWAY

FZD1 APC

1.44e-0320402M11106
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC5B MUC5AC

1.59e-0321402MM15706
PathwayBIOCARTA_GSK3_PATHWAY

FZD1 APC

1.75e-0322402MM1421
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

FZD1 WNT8A WNT8B

1.78e-0385403M48315
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC5B MUC5AC

1.91e-0323402M556
PathwayBIOCARTA_WNT_PATHWAY

FZD1 APC

1.91e-0323402MM1527
PathwayWNT_SIGNALING

FZD1 WNT8A APC

2.03e-0389403M5493
PathwayBIOCARTA_WNT_PATHWAY

FZD1 APC

2.08e-0324402M16517
PathwayREACTOME_SEPARATION_OF_SISTER_CHROMATIDS

RGPD4 RGPD8 RGPD3 RGPD1

2.12e-03193404MM14890
PathwayKEGG_PATHWAYS_IN_CANCER

FZD1 WNT8A WNT8B APC2 APC

2.14e-03325405M12868
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT8A WNT8B

2.26e-0325402MM14940
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

FZD1 WNT8A WNT8B

2.37e-0394403M797
PathwayREACTOME_DECTIN_2_FAMILY

MUC5B MUC5AC

2.44e-0326402M27483
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT8A WNT8B

2.44e-0326402M27239
PathwayREACTOME_MITOTIC_PROMETAPHASE

RGPD4 RGPD8 RGPD3 RGPD1

2.50e-03202404MM15362
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

FZD1 APC2 APC

2.67e-0398403M39731
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR

WNT8A WNT8B

2.83e-0328402M47835
PathwayKEGG_MELANOGENESIS

FZD1 WNT8A WNT8B

2.91e-03101403M7761
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT8A WNT8B

3.04e-0329402M47372
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT8A WNT8B

3.04e-0329402M47377
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

FZD1 WNT8A WNT8B APC

4.17e-03233404M27099
PathwayREACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

RGPD4 RGPD8 RGPD3 RGPD1

4.23e-03234404MM14898
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

FZD1 WNT8A WNT8B

4.51e-03118403M39852
PathwayREACTOME_SIGNALING_BY_WNT

FZD1 WNT8A WNT8B APC

4.56e-03239404MM14756
PathwayBIOCARTA_ALK_PATHWAY

FZD1 APC

4.91e-0337402M17400
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

GRM1 GRM6

4.91e-0337402MM15067
PathwayKEGG_MEDICUS_REFERENCE_TIGHT_JUNCTION_ACTIN_SIGNALING_PATHWAY

CLDN16 ARPC1B

4.91e-0337402M47769
PathwayREACTOME_DISEASES_OF_METABOLISM

THSD4 MUC5B THSD7B MUC5AC

5.35e-03250404M27554
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

GRM1 GRM6

5.44e-0339402M793
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THSD4 THSD7B

5.44e-0339402M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THSD4 THSD7B

5.44e-0339402MM15165
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

FZD1 APC

6.89e-0344402MM15878
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

RGPD4 RGPD8 RGPD3 RGPD1

7.09e-03271404MM15388
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

RGPD4 RGPD8 RGPD3 RGPD1

7.09e-03271404MM15406
PathwayPID_PS1_PATHWAY

FZD1 APC

7.51e-0346402M70
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

RGPD4 RGPD8 RGPD3 RGPD1

7.65e-03277404MM15414
PathwayWP_BRAINDERIVED_NEUROTROPHIC_FACTOR_BDNF_SIGNALING

DPYSL2 NTRK3 APC

7.82e-03144403M39691
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.16e-13751515710750
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751421205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751418949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751425187515
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-1075149037092
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-1075148603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751426632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751424403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751423818861
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751411353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751430944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751438838144
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751423536549
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-1075147559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751417372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751438657106
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751412191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751422821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-10751420682751
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RGPD8 RGPD3 RGPD1

2.86e-10851422262462
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RGPD8 RGPD3 RGPD1

2.86e-10851421670213
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RGPD8 RGPD3 RGPD1

2.86e-10851428745977
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RGPD8 RGPD3 RGPD1

2.86e-10851427412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RGPD8 RGPD3 RGPD1

2.86e-10851421310149
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RGPD8 RGPD3 RGPD1

5.14e-10951418394993
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RGPD8 RGPD3 RGPD1

5.14e-10951411553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RGPD8 RGPD3 RGPD1

5.14e-10951410601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RGPD8 RGPD3 RGPD1

5.14e-1095149733766
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RGPD8 RGPD3 RGPD1

5.14e-10951428100513
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RGPD8 RGPD3 RGPD1

5.14e-10951428877029
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RGPD8 RGPD3 RGPD1

5.14e-10951417887960
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RGPD8 RGPD3 RGPD1

8.55e-10105148857542
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RGPD8 RGPD3 RGPD1

8.55e-101051427160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RGPD8 RGPD3 RGPD1

8.55e-101051416332688
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RGPD8 RGPD3 RGPD1

8.55e-101051421859863
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RGPD8 RGPD3 RGPD1

1.34e-091151435771867
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RGPD8 RGPD3 RGPD1

1.34e-091151417069463
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RGPD8 RGPD3 RGPD1

1.34e-091151434110283
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RGPD8 RGPD3 RGPD1

2.90e-091351431427429
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RGPD8 RGPD3 RGPD1

5.53e-091551414697343
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RGPD8 RGPD3 RGPD1

2.94e-082251427717094
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RGPD8 RGPD3 RGPD1

2.92e-073851412791264
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

RGPD4 RGPD8 RGPD3 RGPD1 APC RGPD5

7.43e-0721551635973513
Pubmed

SAGE reveals expression of Wnt signalling pathway members during mouse prostate development.

FZD1 WNT8A WNT8B

1.07e-061451316378759
Pubmed

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

FZD1 WNT8A WNT8B

1.99e-061751328733458
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

2.11e-0625127513696
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

2.11e-06251234058148
Pubmed

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium.

APC2 APC

2.11e-06251227694902
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

2.11e-06251237146737
Pubmed

Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P.

APC ALOX15

2.11e-06251232814052
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

2.11e-06251214988081
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

2.11e-06251215563276
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

2.11e-06251217621824
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

2.11e-06251224317696
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

2.11e-06251222391959
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

2.11e-06251214718370
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

2.11e-06251235776514
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

2.11e-06251224327612
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

2.11e-06251221653907
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

2.11e-06251231400758
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5B MUC5AC

2.11e-06251236427316
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

2.11e-06251228607090
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5B MUC5AC

2.11e-06251223272068
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

2.11e-06251231030254
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5B MUC5AC

2.11e-06251227729120
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

2.11e-06251223527003
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

2.11e-06251237450367
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

2.11e-06251216540890
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5B MUC5AC

2.11e-06251236111525
Pubmed

Expression and regulation of WNT8A and WNT8B mRNAs in human tumor cell lines: up-regulation of WNT8B mRNA by beta-estradiol in MCF-7 cells, and down-regulation of WNT8A and WNT8B mRNAs by retinoic acid in NT2 cells.

WNT8A WNT8B

2.11e-06251211956596
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

2.11e-06251227845589
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

2.11e-06251227435107
Pubmed

APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression.

APC2 APC

2.11e-06251231291912
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

2.11e-06251226871672
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5B MUC5AC

2.11e-06251232348677
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

2.11e-06251211587997
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5B MUC5AC

2.11e-06251224332705
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

2.11e-06251234656442
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5B MUC5AC

6.32e-06351227776277
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5B MUC5AC

6.32e-06351229286856
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5B MUC5AC

6.32e-06351236675209
Pubmed

Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells.

TLR3 MUC5AC

6.32e-06351226100173
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5B MUC5AC

6.32e-06351229802623
Pubmed

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.

MUC5B MUC5AC

6.32e-06351234158522
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5B MUC5AC

6.32e-06351229604272
Pubmed

IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.

MUC5B MUC5AC

6.32e-06351219596978
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

MUC5B MUC5AC

6.32e-06351219556605
Pubmed

Aquaporin 5 expression increases mucin production in lung adenocarcinoma.

MUC5B MUC5AC

6.32e-06351221455588
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

MUC5B MUC5AC

6.32e-06351220422702
Pubmed

Rhinovirus-induced major airway mucin production involves a novel TLR3-EGFR-dependent pathway.

TLR3 MUC5AC

6.32e-06351218978302
Pubmed

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.

APC2 APC

6.32e-06351223840886
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC5AC

6.32e-06351219718741
Pubmed

A role for Wnt/beta-catenin signaling in lens epithelial differentiation.

FZD1 WNT8A WNT8B

6.68e-062551312812787
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

RGPD4 RGPD8 RGPD3 RGPD1

7.97e-068651437253089
Pubmed

Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.

FZD1 WNT8A WNT8B

8.48e-062751317804636
Pubmed

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.

FZD1 WNT8A WNT8B

9.48e-062851320940229
Pubmed

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

FZD1 WNT8A WNT8B APC

9.55e-069051419515997
Pubmed

3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).

FZD1 WNT8A WNT8B

1.06e-052951318364260
Pubmed

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

MUC5B MUC5AC

1.26e-05451231582416
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC5AC

1.26e-05451225638393
InteractionRGPD4 interactions

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.95e-0922505int:RGPD4
InteractionRGPD2 interactions

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

5.93e-0927505int:RGPD2
InteractionRGPD3 interactions

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.09e-0747505int:RGPD3
InteractionRGPD1 interactions

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.34e-0749505int:RGPD1
InteractionRGPD8 interactions

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.08e-0674505int:RGPD8
InteractionRAN interactions

RGPD4 DPYSL2 RGPD8 FOLR1 RGPD3 RGPD1 WDFY4 NXT2 RGPD5

2.21e-06475509int:RAN
InteractionRGPD5 interactions

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

3.95e-0696505int:RGPD5
InteractionNPIPB6 interactions

RGPD8 RGPD1 RGPD5

1.14e-0518503int:NPIPB6
InteractionFBXW10B interactions

FBXW10B FBXW10

1.81e-053502int:FBXW10B
InteractionRANBP2 interactions

RGPD4 RGPD8 RGPD3 RGPD1 APC NXT2 RGPD5

2.88e-05361507int:RANBP2
InteractionRPS29 interactions

KLF8 PLEKHG4 FOLR1 NTRK3 ARPC1B

8.67e-05182505int:RPS29
InteractionIRAK3 interactions

FOLR1 NTRK3 ECM1

9.68e-0536503int:IRAK3
InteractionRCC1 interactions

DPYSL2 RGPD8 RGPD3 RGPD1 RGPD5

1.38e-04201505int:RCC1
Cytoband2q13

RGPD8 RGPD3 RGPD5

6.15e-05685132q13
Cytoband17p12

FBXW10B FBXW10

1.38e-034951217p12
CytobandEnsembl 112 genes in cytogenetic band chr5q22

TMEM232 APC

1.99e-0359512chr5q22
CytobandEnsembl 112 genes in cytogenetic band chr2q12

RGPD4 RGPD3

3.80e-0382512chr2q12
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

4.62e-06115395769
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

APC2 APC GPRASP2

1.08e-0443393409
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM1 GRM6

1.26e-048392281
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

2.46e-0411392559
GeneFamilyWnt family|Endogenous ligands

WNT8A WNT8B

7.58e-0419392360
GeneFamilyCD molecules|Mucins

MUC5B MUC5AC

9.28e-0421392648
GeneFamilyWD repeat domain containing

FBXW10B FBXW10 WDFY4 ARPC1B

2.38e-03262394362
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 RGPD8 RGPD3 RGPD1

4.99e-0733514MM477
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RGPD8 RGPD3 RGPD1

1.48e-0643514MM3857
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOLR1 TFPI2 LRATD1 MUC5B MUC5AC ALOX15

9.68e-08196516b246e482f012dd9782b49c2a953acedfa3c1139d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOLR1 TFPI2 LRATD1 MUC5B MUC5AC ALOX15

9.68e-08196516808c0a7d1889a8f3508ed9790c6dc7ec16bbc840
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP95 TFPI2 FUT3 MUC5AC ALOX15

2.98e-061965153e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP95 TFPI2 FUT3 MUC5AC ALOX15

2.98e-061965151efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOLR1 TFPI2 LRATD1 ECM1 MUC5AC

3.05e-06197515ac9c0c25cfeaabd53d332982c73fc6c47b0c6478
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOLR1 TFPI2 LRATD1 ECM1 MUC5AC

3.05e-06197515b57d2e3413ef6dd1da56c45087926f2f3eab876c
ToppCellSevere_COVID-19-Epithelial-transitional_Epi|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

CFAP95 TFPI2 FUT3 MUC5AC ALOX15

3.05e-061975155ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFAP95 TFPI2 FUT3 MUC5AC ALOX15

3.05e-0619751508b371309cd790b171ed76cabc7d910e71cd2835
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THSD4 FBXW10B FAP THSD7B ECM1

3.05e-061975152872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP95 TFPI2 FUT3 MUC5AC ALOX15

3.05e-061975159f49feee38647bbf964974aac96fa75602186b5c
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

CFAP95 ZNF775 CLEC4M WDFY4

2.06e-051415147671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellICU-SEP-Lymphocyte-T_NK-Treg|ICU-SEP / Disease, Lineage and Cell Type

USP18 RGPD1 SPOCK2 RGPD5

2.30e-05145514ee99b58462f955b96d036aa67e343db047d66f64
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-DC1|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CFAP95 TLR3 WDFY4 ALOX15

4.38e-05171514459e1ac0b89571c39db98c0f578eca8f46caa8e3
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FOLR1 SPOCK2 MUC5B MUC5AC

4.48e-051725140be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOLR1 MUC5B FUT3 MUC5AC

4.58e-05173514e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCell11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

TFPI2 NTRK3 SPOCK2 ALOX15

4.58e-051735146989c9cebcd81eccceac7e5a86152676ee959386
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|356C / Donor, Lineage, Cell class and subclass (all cells)

FOLR1 TFPI2 MUC5B MUC5AC

4.79e-05175514af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|356C / Donor, Lineage, Cell class and subclass (all cells)

FOLR1 TFPI2 MUC5B MUC5AC

4.79e-051755144bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCellICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, Lineage and Cell Type

FBXW10 TLR3 WDFY4 ALOX15

5.01e-0517751433cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCellwk_08-11-Epithelial-PNS-Proliferating_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TFPI2 NTRK3 ARPC1B ALOX15

5.23e-05179514ab23fee9adab1e63d5b5cd9faba6b9a92beef425
ToppCellnormal_Lymph_Node-Myeloid_cells-CD141+_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

CFAP95 DPYSL2 WDFY4 ALOX15

5.23e-05179514ec995ccd6e1dbd06287ad836c232d9aed1cf94a8
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAP TRIM39 GPRASP2 ZRANB3

5.23e-05179514ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCellControl-Epithelial-Goblet|Control / Disease state, Lineage and Cell class

FOLR1 TFPI2 MUC5B MUC5AC

5.35e-051805145293d23b8b8ea587239ffde561b70bad01632521
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CFAP95 MUC5B MUC5AC ALOX15

5.35e-05180514d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF775 FOLR1 NTRK3 THSD7B

5.35e-05180514d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF775 FOLR1 NTRK3 THSD7B

5.35e-05180514573308d43425d9fba20787abdb7f8efefc48efb5
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP95 TMEM232 FOLR1 PKHD1

5.46e-05181514e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP95 TMEM232 FOLR1 PKHD1

5.46e-0518151411cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP95 TMEM232 FOLR1 PKHD1

5.46e-051815145ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

CFAP95 TLR3 WDFY4 ALOX15

5.70e-05183514e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 MUC5B PKD1L2 GRM1

5.82e-051845142cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 MUC5B PKD1L2 GRM1

5.82e-05184514ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 MUC5B PKD1L2 GRM1

5.82e-051845142b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP95 TMEM232 MUC5B ALOX15

5.82e-0518451407c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellControl-Epithelial-Goblet|World / Disease state, Lineage and Cell class

FOLR1 TFPI2 MUC5B MUC5AC

5.95e-051855149a793e6016295a63820e9d7563f195494ac692e7
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TFPI2 SPOCK2 THSD7B ALOX15

6.33e-051885149655a4c47b644a870017d349b99063e17dbae572
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FZD1 FAP TFPI2 TLR3

6.33e-05188514c9270517e6940e9793586f67f02431210552f278
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP95 TFPI2 MUC5AC ALOX15

6.59e-051905142fdc024d3d673a0134b74b4c5a63afe924995730
ToppCellwk_08-11-Mesenchymal-Mesothelial-intermediate_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TFPI2 CLDN16 SPOCK2 ALOX15

6.87e-05192514ac9e5288ecd4b1e142f2e15a1fcd11c8eb9e15cd
ToppCellLAM-Epithelial-AirwayEpi|LAM / Condition, Lineage and Cell class

CFAP95 TMEM232 MUC5B ALOX15

6.87e-051925147404fc65be3b7bd09447725b43fa31819004dfee
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP95 TMEM232 FOLR1 MUC5B

6.87e-051925146c269d2426f76559d2ed3bf2169eb4be5fc7ad6d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 TFPI2 PKHD1 SPOCK2

7.01e-051935140f2167eef8203a5659c8c72e4e77646003d64797
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP95 TMEM232 MUC5B MUC5AC

7.29e-051955149651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRATD1 MUC5B FUT3 MUC5AC

7.44e-05196514a4d05d85fbafa869df19bba3881020ea433d81fb
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LRATD1 MUC5B FUT3 MUC5AC

7.44e-0519651491a3c3091064f1f5a3bdc1dd5883fc24dce8ff05
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRATD1 MUC5B FUT3 MUC5AC

7.44e-05196514e819088a74d29e958371aa851ac9c74ec55367b7
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

LRATD1 MUC5B FUT3 MUC5AC

7.44e-05196514e675d661b6494ac3a85ba7ee5bdeaa98b8bbe957
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5B FUT3 MUC5AC ALOX15

7.58e-05197514da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5B FUT3 MUC5AC ALOX15

7.58e-05197514a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FOLR1 MUC5B FUT3 MUC5AC

7.58e-05197514e2c820c4e4a6cd01ceb020473286e3f5d4e3718e
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-Treg|ICU-SEP / Disease, condition lineage and cell class

USP18 SPOCK2 ECM1 RGPD5

7.58e-05197514c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCellMild_COVID-19-Epithelial-Basal/Club|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

LRATD1 MUC5B FUT3 MUC5AC

7.58e-051975144cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5B FUT3 MUC5AC ALOX15

7.58e-051975143fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCellproximal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5B FUT3 MUC5AC ALOX15

7.73e-051985143477202c4f702d8f75231b13d4b5216f56d981d7
ToppCellproximal-Epithelial-Goblet|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5B FUT3 MUC5AC ALOX15

7.73e-05198514e7e1c430486a81280abc4a7e7f5bc3713dd20737
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TFPI2 MUC5B MUC5AC ALOX15

7.73e-05198514484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCellproximal-Epithelial-Goblet-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5B FUT3 MUC5AC ALOX15

7.73e-05198514da7b40eb00bb5e454e1cfcd1219dc0d84712592a
ToppCellmedial-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR1 MUC5B FUT3 MUC5AC

7.89e-051995144737250b7ffa7cc19eb6b057d35d78f13b1afe66
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRATD1 MUC5B FUT3 MUC5AC

7.89e-05199514d04062d86643e5712cc2f519f4f36e643d404a16
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FOLR1 MUC5B FUT3 MUC5AC

7.89e-0519951470c0b9cff195d3d24e98443a729e211cac20c90f
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FOLR1 MUC5B FUT3 MUC5AC

7.89e-05199514f37114cf849837fdb8ed9a767de773e8681b7df3
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LRATD1 MUC5B FUT3 MUC5AC

7.89e-05199514a3f83fe5c3c557cd3ef8f5632f7fba5cf1859937
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LRATD1 MUC5B FUT3 MUC5AC

7.89e-05199514644197ff7e3299587881dd678836262e670ed4a8
ToppCellmedial-Epithelial-Mucous|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR1 MUC5B FUT3 MUC5AC

7.89e-051995144385963ab25b5378e7964b984028c25b27e5794e
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Club|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FOLR1 TFPI2 MUC5B MUC5AC

7.89e-051995142b17694cffbec28a2c8f165dfcff6bab94aa0f4c
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5B+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

FOLR1 TFPI2 MUC5B MUC5AC

7.89e-051995144ab45996e6bca406c77895a5998982b8ab1cf210
ToppCellproximal-Epithelial-Mucous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR1 TFPI2 MUC5B MUC5AC

7.89e-05199514baac580484124b7c36717b607adcf2cb446e631d
ToppCellproximal-Epithelial-Mucous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR1 TFPI2 MUC5B MUC5AC

7.89e-0519951415ba36fa6ad73d0e959e42f18d7acbc14e310dc9
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Club|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FOLR1 TFPI2 MUC5B MUC5AC

7.89e-05199514111cfd589ec6795075d8d88d7664bfb23eba5bf6
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B FUT3 MUC5AC ALOX15

7.89e-051995143c3133d0aa65338a576634def13e7f0f5c573a10
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Club-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOLR1 TFPI2 MUC5B MUC5AC

7.89e-05199514d583290a1d288b749ad17bc501c1487268c6551c
ToppCellproximal-3-Epithelial-Mucous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR1 TFPI2 MUC5B MUC5AC

7.89e-051995143018378860de084662be0cc46fce421db3bb9ec9
ToppCelldistal-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR1 MUC5B FUT3 MUC5AC

7.89e-05199514c0275b5011c2bb08e873955afe2e213ec8070d0e
ToppCelldistal-Epithelial-Mucous-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR1 MUC5B FUT3 MUC5AC

7.89e-051995140af89ef40807fc4ad79ab82a2186ab6e866c6931
ToppCellmedial-Epithelial-Mucous-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR1 MUC5B FUT3 MUC5AC

7.89e-0519951453198bcf5f2f012a3ed1600d95c0923d6976a099
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B FUT3 MUC5AC ALOX15

7.89e-05199514a706ad5cd5e0dc8d7e925a05e45b07d35963f294
ToppCellSevere_COVID-19-Epithelial-Basal/Club|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

LRATD1 MUC5B FUT3 MUC5AC

7.89e-051995142a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRATD1 MUC5B FUT3 MUC5AC

7.89e-05199514fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCelldistal-Epithelial-Mucous|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR1 MUC5B FUT3 MUC5AC

7.89e-05199514a7fe7b792d696f369ad0310a772160a1729ef223
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FOLR1 MUC5B FUT3 MUC5AC

8.04e-05200514292c63693eb7f435335a8cfba07aa35b72139393
ToppCellBiopsy_Control_(H.)-Epithelial-Differentiating_Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CFAP95 TMEM232 MUC5B ALOX15

8.04e-05200514a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FOLR1 MUC5B FUT3 MUC5AC

8.04e-05200514133853d0f55c63ebe94dd54151f9f1f90650a0d8
ToppCell(51)_cDC1|World / shred on Cell_type and subtype

DPYSL2 TLR3 WDFY4 ALOX15

8.68e-05204514a8cf4180c406674b7541917d1fc6127686ba5f8a
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FAP TFPI2 CATSPERG

1.99e-049951398c40a27432929434879c9e7283a14102f405f39
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FAP TFPI2 CATSPERG

1.99e-0499513d6bd8075dc7aba2034ea78b1389868282bc80a2d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Intermediate|GW26 / Sample Type, Dataset, Time_group, and Cell type.

THSD4 TFPI2 ZNF229

2.65e-0410951348f675d36fece070410eb9cfe64805f4629e290f
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF8 TRIM39 ZRANB3

3.60e-04121513e82c9e10b98c8d7ad828cf8ac19a2342014be2ba
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Calb1_(Superficial_layer_pyramidal_cells--Layer_2/3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FOLR1 PKHD1 PKD1L2

4.05e-041265137dcc79bf35482e8e5e5a1de7279ba080edb70522
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT1|E18.5-samps / Age Group, Lineage, Cell class and subclass

KLF8 FOLR1 SPOCK2

4.44e-04130513eb16a8f8f62add5fdd29c78d4608b6d1a06767f1
ToppCellGlobus_pallidus-Macroglia-CSF_related-EPENDYMAL-Ependymal_(Ccdc153)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CFAP95 TMEM232 FOLR1

4.74e-041335132caaacb4fb4358c5589c81eaf8dffb85f318fb13
ToppCellGlobus_pallidus-Macroglia-CSF_related-EPENDYMAL|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CFAP95 TMEM232 FOLR1

4.74e-041335132d0cade52d79c3d0b6f77418103244150e2ea7fb
ToppCellGlobus_pallidus-Macroglia-CSF_related-EPENDYMAL-Ependymal_(Ccdc153)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CFAP95 TMEM232 FOLR1

4.74e-0413351325ea1d82a0fc9fed191b9dd33f2a35404a665e7d
ToppCellGlobus_pallidus-Macroglia-CSF_related|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CFAP95 TMEM232 FOLR1

4.74e-0413351351c60b6d5648968783bffbb22c28d9abaf6243d5
ToppCellGlobus_pallidus-Macroglia-CSF_related-EPENDYMAL-Ependymal_(Ccdc153)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CFAP95 TMEM232 FOLR1

4.74e-04133513a653282bf871dc9eb47fbf1d55b1eb32ae749c04
ToppCellsevere-Lymphocytic-B_cells_2|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

APC2 ZNF229 WDFY4

5.06e-0413651356a7b5c2e098b4a49124d1b905257a52eb38b519
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TFPI2 WNT8A CATSPERG

5.17e-041375134dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TFPI2 WNT8A CATSPERG

5.17e-04137513c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCellAT1-AT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

THSD4 APC2 SPOCK2

5.50e-0414051345d52a086ced8d58e01ac51ac4a90338e8649b16
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_2|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TFPI2 NTRK3 GPRASP2

5.86e-04143513abe6ec0f6956b87f394d537926eb2427fcfad93f
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-2|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

FAP LRTM2 ECM1

6.10e-04145513f9aa7f2401e26f1e8cec1112a71c16e1c2784893
DrugClenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; PC3; HT_HG-U133A

THSD4 TFPI2 WNT8B APC2 MUC5B MUC5AC

2.02e-061685164671_UP
DrugCamptothecine (S,+) [7689-03-4]; Up 200; 11.4uM; MCF7; HT_HG-U133A

FZD1 FOLR1 TFPI2 SPOCK2 MUC5B MUC5AC

3.21e-061825162321_UP
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

FZD1 TFPI2 SPOCK2 GRM1 MUC5AC NXT2

4.64e-061945161632_UP
Drugerythromycin stearate

FAP APC2 APC NOX3 ALOX15

4.94e-06111515CID000012559
Drug2-aminosuberic acid

GRM1 GRM6

4.90e-055512CID000077937
DrugLY393675

GRM1 GRM6

4.90e-055512CID005311262
DrugDMeOB

GRM1 GRM6

4.90e-055512CID002061047
Drugtyrphostin B52

GRM1 GRM6

4.90e-055512CID005328773
DrugAC1MBZ3L

GRM1 GRM6

7.34e-056512CID002733524
DrugMTEP

GRM1 GRM6

7.34e-056512CID009794218
DrugSIB-1757

GRM1 GRM6

7.34e-056512CID006304902
DrugPhenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A

THSD4 KLF8 NTRK3 SPOCK2 C8A

7.47e-051955154747_UP
DrugEthionamide [536-33-4]; Up 200; 24uM; PC3; HT_HG-U133A

THSD4 APC NOX3 C8A MUC5AC

7.47e-051955154593_UP
DrugCyclopenthiazide [742-20-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A

KLF8 APC MUC5B FUT3 GRM1

7.47e-051955154813_UP
DrugBenzbromarone [3562-84-3]; Up 200; 9.4uM; PC3; HT_HG-U133A

FZD1 APC2 SPOCK2 CLEC4M GRM1

8.22e-051995156669_UP
DrugCGS 19755

NTRK3 GRM1 GRM6

8.45e-0538513CID000068736
DrugCDPPB

GRM1 GRM6

1.03e-047512CID011245456
Drugazetidine-2,4-dicarboxylic acid

GRM1 GRM6

1.03e-047512CID000005370
DrugMCCG-I

GRM1 GRM6

1.03e-047512CID005311457
Drug1-aminocyclopentane-1,3-dicarboxylate

APC C8A GRM1 GRM6

1.12e-04111514CID000001310
Diseasefamilial adenomatous polyposis 1 (implicated_via_orthology)

APC2 APC

2.48e-062472DOID:0080409 (implicated_via_orthology)
Diseaseidiopathic pulmonary fibrosis

MUC5B FUT3 MUC5AC

1.04e-0457473EFO_0000768
DiseaseColorectal Carcinoma

DPYSL2 TFPI2 WNT8B APC2 PKHD1 APC GRM1

1.15e-04702477C0009402
Diseasepancreatic ductal carcinoma (is_marker_for)

NTRK3 MUC5B MUC5AC

1.28e-0461473DOID:3587 (is_marker_for)
Diseasepulmonary fibrosis

MUC5B MUC5AC

1.35e-0411472EFO_0009448
Diseaseinterstitial lung disease

MUC5B THSD7B MUC5AC

1.69e-0467473EFO_0004244
DiseaseAlcoholic Intoxication, Chronic

DPYSL2 FOLR1 THSD7B GRM1

8.73e-04268474C0001973
Diseasecolorectal cancer (implicated_via_orthology)

APC2 APC

1.05e-0330472DOID:9256 (implicated_via_orthology)
Diseaseasthma (is_marker_for)

TLR3 MUC5B MUC5AC

1.07e-03126473DOID:2841 (is_marker_for)
Diseasechronic rhinosinusitis

TMEM232 ALOX15

1.35e-0334472EFO_1000024
DiseaseInflammatory Bowel Diseases

APC2 APC

1.43e-0335472C0021390
DiseaseSpinocerebellar Ataxia Type 4

PLEKHG4 GRM1

1.43e-0335472C0752122
DiseaseCOVID-19 symptoms measurement

MUC5B MUC5AC

1.43e-0335472EFO_0600019

Protein segments in the cluster

PeptideGeneStartEntry
ASWRLWAIKDFQECT

CATSPERG

31

Q6ZRH7
LSNWSEWTDCFPCQD

C8A

41

P07357
SICYFEQENDWWVCK

ARPC1B

121

O15143
WKIFSTKEWFCRIND

FBXW10

36

Q5XX13
TKCRGLWWECVTNAF

CLDN16

41

Q9Y5I7
TTRCQPKCEWTEWFD

MUC5B

1781

Q9HC84
CKQLCTERQKSWWDA

RGPD5

521

Q99666
CKQLCTERQKSWWDA

RGPD8

521

O14715
WKIFSTKEWFCRIND

FBXW10B

36

O95170
RSCQDWCDRKQHWLE

CFAP95

6

Q5VTT2
FFNCSCDIRWMQLWQ

NTRK3

161

Q16288
DQWREWADSKSCCDY

DPYSL2

121

Q16555
CTWDGCSWKFARSDE

KLF8

306

O95600
CWKDLDDFNRIFWCG

ALOX15

196

P16050
EICWTNSESFAAWCR

LRATD1

206

Q96KN4
DCHLRCTWTKWFDID

MUC5AC

3221

P98088
NDKELRFQWSCGSCW

PKD1L2

586

Q7Z442
CKQLCTERQKSWWDA

RGPD3

521

A6NKT7
FRDQWERSWVAQSCK

FZD1

561

Q9UP38
QIRAYCETCWDWLQA

APC2

376

O95996
WFAEFWEENFNCKLT

GRM6

356

O15303
TCTWKAWEDTLDKYC

ECM1

356

Q16610
VQDEFTCKACDLGWW

GRM1

556

Q13255
KEDCEQWWEDCRTSY

FOLR1

136

P15328
QWWEDCRTSYTCKSN

FOLR1

141

P15328
CTERQKSWWDAVCTL

RGPD1

516

P0DJD0
VWKIASDCFRFQDWS

NXT2

126

Q9NPJ8
FSWALDFCKACWKLQ

FUT3

331

P21217
CKQLCTERQKSWWDA

RGPD4

521

Q7Z3J3
HNFCKACITRWWEDL

TRIM39

46

Q9HCM9
ECDCNLREFKHWMEW

LRTM2

201

Q8N967
WRFAVCSFRDAWEEE

PLEKHG4

21

Q58EX7
SWFWDRDEACFDLNP

GPRASP2

451

Q96D09
WQFDCTDLWETCVRC

PKHD1

656

P08F94
WICRDARAFEWFADL

NOX3

441

Q9HBY0
EQIRAYCETCWEWQE

APC

411

P25054
WNDNRCDVDNYWICK

CLEC4M

376

Q9H2X3
CDFREDWQTWDCPKT

FAP

321

Q12884
IEECKYQFAWDRWNC

WNT8B

51

Q93098
PFDCTCESIAWFVNW

TLR3

646

O15455
NQEESCKVDDFSWAW

TMEM232

341

C9JQI7
WNRTFSWGFDDFSCC

WDFY4

2901

Q6ZS81
FICNECGKSFSWWSA

ZNF775

446

Q96BV0
CWFCGRVFDNQDTWA

ZNF518A

1451

Q6AHZ1
TVYKCNWDDDSFCWI

ZNF229

211

Q9UJW7
WFCFNDSNICLVSWE

USP41

331

Q3LFD5
WFCFNDSNICLVSWE

USP18

331

Q9UMW8
FYTWEACDDACWRIE

TFPI2

76

P48307
IEECKFQFAWERWNC

WNT8A

51

Q9H1J5
CYSWVLGNWSACKLE

THSD7B

1301

Q9C0I4
SWFLTEWSERCSAEC

THSD4

796

Q6ZMP0
RVSTAEWCFCFWREK

SPOCK2

296

Q92563
WDSRFCSLKCQEEFW

ZRANB3

931

Q5FWF4