Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEF POTEKP POTEE POTEI	9.18e-07	11	148	4	GO:0098973
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEF POTEKP POTEE POTEI	8.87e-05	32	148	4	GO:0099186
GeneOntologyMolecularFunction	structural constituent of synapse	POTEF POTEKP POTEE POTEI	2.61e-04	42	148	4	GO:0098918
GeneOntologyBiologicalProcess	replacement ossification	SIK3 TEK IFT80 MMP13 CSGALNACT1	1.33e-05	43	147	5	GO:0036075
GeneOntologyBiologicalProcess	endochondral ossification	SIK3 TEK IFT80 MMP13 CSGALNACT1	1.33e-05	43	147	5	GO:0001958
GeneOntologyBiologicalProcess	skeletal system morphogenesis	NOG LAMA5 SIK3 TEK SETD2 HOXC4 IFT80 MMP13 CSGALNACT1 MED12	3.06e-05	277	147	10	GO:0048705
GeneOntologyBiologicalProcess	cartilage development	NOG SIK3 DICER1 HOXC4 ADAMTS7 IFT80 MMP13 CSGALNACT1 SMAD1	6.33e-05	243	147	9	GO:0051216
GeneOntologyBiologicalProcess	postsynaptic actin cytoskeleton organization	POTEF POTEKP POTEE POTEI	6.71e-05	31	147	4	GO:0098974
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEF POTEKP POTEE POTEI	7.44e-05	32	148	4	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEF POTEKP POTEE POTEI	7.44e-05	32	148	4	GO:0043189
GeneOntologyCellularComponent	actin filament	POTEF POTEKP TEK POTEE AMOT AVIL POTEI	8.25e-05	146	148	7	GO:0005884
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEF POTEKP POTEE POTEI	2.87e-04	45	148	4	GO:1902562
Domain	Growth_fac_rcpt_	FRAS1 LAMA5 LAMC3 TEK STAB1 IGFBP2 HMCN1 TIE1 EGFR	3.62e-06	156	145	9	IPR009030
Domain	DUF4704	NBEA NBEAL2 LRBA	4.53e-06	5	145	3	IPR031570
Domain	DUF4704	NBEA NBEAL2 LRBA	4.53e-06	5	145	3	PF15787
Domain	PH_BEACH	NBEA NBEAL2 LRBA	9.01e-06	6	145	3	PF14844
Domain	PH-BEACH_dom	NBEA NBEAL2 LRBA	2.49e-05	8	145	3	IPR023362
Domain	-	NBEA NBEAL2 LRBA	2.49e-05	8	145	3	2.30.29.40
Domain	PH_BEACH	NBEA NBEAL2 LRBA	2.49e-05	8	145	3	PS51783
Domain	BEACH	NBEA NBEAL2 LRBA	3.72e-05	9	145	3	PS50197
Domain	Beach	NBEA NBEAL2 LRBA	3.72e-05	9	145	3	PF02138
Domain	-	NBEA NBEAL2 LRBA	3.72e-05	9	145	3	1.10.1540.10
Domain	Beach	NBEA NBEAL2 LRBA	3.72e-05	9	145	3	SM01026
Domain	BEACH_dom	NBEA NBEAL2 LRBA	3.72e-05	9	145	3	IPR000409
Domain	DUF1088	NBEA LRBA	5.99e-05	2	145	2	IPR010508
Domain	DUF1088	NBEA LRBA	5.99e-05	2	145	2	PF06469
Domain	Actin_CS	POTEF POTEE POTEI	2.38e-04	16	145	3	IPR004001
Domain	ACTINS_2	POTEF POTEE POTEI	2.88e-04	17	145	3	PS00432
Domain	Actin/actin-like_CS	POTEF POTEE POTEI	3.43e-04	18	145	3	IPR020902
Domain	Glyco_hydro_31_CS	MGAM GANAB	3.56e-04	4	145	2	IPR030459
Domain	ACTINS_ACT_LIKE	POTEF POTEE POTEI	4.05e-04	19	145	3	PS01132
Domain	EGF	FRAS1 LAMA5 LAMC3 TEK STAB1 FAT2 HMCN1 TIE1	5.06e-04	235	145	8	SM00181
Domain	GLYCOSYL_HYDROL_F31_2	MGAM GANAB	5.89e-04	5	145	2	PS00707
Domain	EGF-like_dom	FRAS1 LAMA5 LAMC3 TEK STAB1 FAT2 HMCN1 TIE1	7.40e-04	249	145	8	IPR000742
Domain	-	EPPK1 PLEC	8.80e-04	6	145	2	3.90.1290.10
Domain	Glyco_hydro_31_AS	MGAM GANAB	8.80e-04	6	145	2	IPR030458
Domain	RNase_Zc3h12a	ZC3H12B ZC3H12C	1.23e-03	7	145	2	PF11977
Domain	Glyco_hydro_31	MGAM GANAB	1.23e-03	7	145	2	IPR000322
Domain	Plectin	EPPK1 PLEC	1.23e-03	7	145	2	PF00681
Domain	Glyco_hydro_31	MGAM GANAB	1.23e-03	7	145	2	PF01055
Domain	Plectin_repeat	EPPK1 PLEC	1.23e-03	7	145	2	IPR001101
Domain	RNase_Zc3h12_NYN	ZC3H12B ZC3H12C	1.23e-03	7	145	2	IPR021869
Domain	GLYCOSYL_HYDROL_F31_1	MGAM GANAB	1.23e-03	7	145	2	PS00129
Domain	PLEC	EPPK1 PLEC	1.23e-03	7	145	2	SM00250
Domain	EGF_LAM_2	LAMA5 LAMC3 STAB1	1.60e-03	30	145	3	PS50027
Domain	EGF_LAM_1	LAMA5 LAMC3 STAB1	1.60e-03	30	145	3	PS01248
Domain	HP	ABLIM1 AVIL	1.63e-03	8	145	2	PS51089
Domain	-	ABLIM1 AVIL	1.63e-03	8	145	2	1.10.950.10
Domain	VHP	ABLIM1 AVIL	1.63e-03	8	145	2	SM00153
Domain	LAMININ_IVA	LAMA5 LAMC3	1.63e-03	8	145	2	PS51115
Domain	Laminin_B	LAMA5 LAMC3	1.63e-03	8	145	2	PF00052
Domain	VHP	ABLIM1 AVIL	1.63e-03	8	145	2	PF02209
Domain	Villin_headpiece	ABLIM1 AVIL	1.63e-03	8	145	2	IPR003128
Domain	LamB	LAMA5 LAMC3	1.63e-03	8	145	2	SM00281
Domain	Na+channel_ASC_CS	ASIC1 ASIC4	1.63e-03	8	145	2	IPR020903
Domain	Laminin_IV	LAMA5 LAMC3	1.63e-03	8	145	2	IPR000034
Domain	Actin	POTEF POTEE POTEI	1.76e-03	31	145	3	IPR004000
Domain	Actin	POTEF POTEE POTEI	1.76e-03	31	145	3	PF00022
Domain	ACTIN	POTEF POTEE POTEI	1.76e-03	31	145	3	SM00268
Domain	ASC	ASIC1 ASIC4	2.08e-03	9	145	2	PF00858
Domain	ASC	ASIC1 ASIC4	2.08e-03	9	145	2	PS01206
Domain	Na+channel_ASC	ASIC1 ASIC4	2.08e-03	9	145	2	IPR001873
Domain	EGF_Lam	LAMA5 LAMC3 STAB1	2.50e-03	35	145	3	SM00180
Domain	Laminin_EGF	LAMA5 LAMC3 STAB1	2.50e-03	35	145	3	PF00053
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF21A RNF44 DLGAP5 LAMA5 SPIRE1 SIK3 BCOR DICER1 STAB1 AMOT NBEAL2 SLMAP ANKIB1 FBXO41 RAB11FIP5 IFT80	1.25e-09	529	149	16	14621295
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FRAS1 EPPK1 LAMA5 CUL9 SPIRE1 LAMC3 ITGA5 ZNF503 PCNX2 PRR12 NCOR1 ZNRF3 ADAMTS7 NBEAL2 TMEM132A HELZ2 PLEC LRBA C1orf50 MED12	6.04e-08	1105	149	20	35748872
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	FNDC3B DDX17 ATXN2 TJP1 PEBP1 G3BP2 HELZ2 ASCC3 CCDC9 PTCD3	1.88e-07	258	149	10	37794589
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 BAG3 DLGAP5 IQCN BCOR NCOR1 ABLIM1 OSBP SETD2 SEC24C EGFR HELZ2 RBM7 PLEC MN1 CCDC9	2.44e-07	774	149	16	15302935
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KIF21A ZNF407 IQCN SETD2 HELZ2 CFAP74 ZC3H12C	3.02e-07	102	149	7	11214970
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEF POTEKP POTEE POTEI	4.26e-07	15	149	4	16824795
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	APAF1 SIK3 DICER1 STAB1 ABLIM1 ZNRF3 AMOT HELZ2 STK38L	6.02e-07	225	149	9	12168954
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	CBLL1 FNDC3B DPY19L1 SLC35E1 ZNF407 ITGA5 DDOST ABLIM1 GANAB PTPRK ATXN2 TJP1 GLE1 AMOT TMEM132A RBM7 RAB11FIP5 PLEC MED12	1.04e-06	1203	149	19	29180619
Pubmed	EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.	FRAS1 BCOR SETD2 AMOT MLLT3	1.28e-06	44	149	5	27505670
Pubmed	Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.	NOG TJP1 PAX3 SMAD1	3.22e-06	24	149	4	36916392
Pubmed	Critical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.	TEK DICER1 TIE1 SMAD1	3.82e-06	25	149	4	24835278
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	TRERF1 BAG3 ETV6 CUL9 NCOR1 SETD2 SEPSECS RBM7 ASCC3	3.86e-06	282	149	9	23667531
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	CBLL1 FNDC3B HLA-E GPX7 LAMA5 ETV6 SIK3 GCNT2 DDOST GANAB SEC24C GVINP1 PTPRK EGFR ATXN2 TJP1 RAB11FIP5 PLEC CSGALNACT1 PTCD3	4.18e-06	1451	149	20	30550785
Pubmed	Aberrant Bmp signaling and notochord delamination in the pathogenesis of esophageal atresia.	NOG TJP1 SMAD1	6.35e-06	9	149	3	17260385
Pubmed	Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system.	CACNA1D TEK TIE1	6.35e-06	9	149	3	8415706
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTEKP POTEE POTEI	6.35e-06	9	149	3	16364570
Pubmed	BCoR, a novel corepressor involved in BCL-6 repression.	BCOR NCOR1 MLLT3	9.05e-06	10	149	3	10898795
Pubmed	Precise spatial restriction of BMP signaling in developing joints is perturbed upon loss of embryo movement.	NOG PAX3 SMAD1	1.24e-05	11	149	3	29467244
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 BAG3 BCOR PRR12 NCOR1 AMOT PLEC LRBA ASCC3 MED12	1.40e-05	418	149	10	34709266
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRERF1 CBLL1 ASIC1 KIF21A DLGAP5 NBEA SIK3 BCOR NCOR1 ABLIM1 SEC24C ATXN2 TJP1 G3BP2 FBXO41	1.80e-05	963	149	15	28671696
Pubmed	Noggin is associated with a poor prognosis of gastric cancer by promoting the proliferation of gastric cancer cells via the upregulation of EGFR.	NOG EGFR	1.82e-05	2	149	2	32705152
Pubmed	Evidence for heterotypic interaction between the receptor tyrosine kinases TIE-1 and TIE-2.	TEK TIE1	1.82e-05	2	149	2	10995770
Pubmed	Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function.	PTPRK EGFR	1.82e-05	2	149	2	16263724
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEF POTEE	1.82e-05	2	149	2	19669888
Pubmed	TWEAK Negatively Regulates Human Dicer.	TNFSF12 DICER1	1.82e-05	2	149	2	29657270
Pubmed	Myeloid neoplasms with t(12;22)(p13;q12)/MN1-EVT6: a systematic review of 12 cases.	ETV6 MN1	1.82e-05	2	149	2	29273914
Pubmed	Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer.	EGFR ROS1	1.82e-05	2	149	2	24349229
Pubmed	Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands.	TEK TIE1	1.82e-05	2	149	2	20227369
Pubmed	Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice.	UNC13D NBEAL2	1.82e-05	2	149	2	28077416
Pubmed	BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1, SIX, and MYC Activity.	BCOR MLLT3	1.82e-05	2	149	2	32954361
Pubmed	Regulation of ASIC activity by ASIC4--new insights into ASIC channel function revealed by a yeast two-hybrid assay.	ASIC1 ASIC4	1.82e-05	2	149	2	18662336
Pubmed	Loss of MED12 Induces Tumor Dormancy in Human Epithelial Ovarian Cancer via Downregulation of EGFR.	EGFR MED12	1.82e-05	2	149	2	29735544
Pubmed	Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioma cell invasion through induction of NF-κB-inducing kinase (NIK) and noncanonical NF-κB signaling.	TNFSF12 MAP3K14	1.82e-05	2	149	2	25622756
Pubmed	Ketolysis is required for the proper development and function of the somatosensory nervous system.	OXCT1 AVIL	1.82e-05	2	149	2	37100111
Pubmed	IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer.	ITGA5 IGFBP2	1.82e-05	2	149	2	38918360
Pubmed	The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.	TEK TIE1	1.82e-05	2	149	2	8846781
Pubmed	Heterogeneity of Tie2 expression in tumor microcirculation: influence of cancer type, implantation site, and response to therapy.	RAG1 TEK	1.82e-05	2	149	2	16314485
Pubmed	NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways.	BAG3 MAP3K14	1.82e-05	2	149	2	25766331
Pubmed	Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein.	ETV6 NCOR1	1.82e-05	2	149	2	11001911
Pubmed	Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis.	TEK TIE1	1.82e-05	2	149	2	14530387
Pubmed	Tie2 receptor expression and phosphorylation in cultured cells and mouse tissues.	TEK TIE1	1.82e-05	2	149	2	9108247
Pubmed	Integrin α5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation via N-Glycosylation.	ITGA5 EGFR	1.82e-05	2	149	2	26483551
Pubmed	Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells.	TEK TIE1	1.82e-05	2	149	2	8395828
Pubmed	Plakins in development and disease.	EPPK1 PLEC	1.82e-05	2	149	2	17499243
Pubmed	IGFBP2 induces podocyte apoptosis promoted by mitochondrial damage via integrin α5/FAK in diabetic kidney disease.	ITGA5 IGFBP2	1.82e-05	2	149	2	38796567
Pubmed	Localization of the angiopoietin receptors Tie-1 and Tie-2 on the primary cilia in the female reproductive organs.	TEK TIE1	1.82e-05	2	149	2	15893943
Pubmed	Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11.	ETV6 MN1	1.82e-05	2	149	2	7731705
Pubmed	Integrin alpha5/beta1 mediates fibronectin-dependent epithelial cell proliferation through epidermal growth factor receptor activation.	ITGA5 EGFR	1.82e-05	2	149	2	10888683
Pubmed	Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival.	TEK TIE1	1.82e-05	2	149	2	17504972
Pubmed	Oxidative inhibition of receptor-type protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes.	PTPRK EGFR	1.82e-05	2	149	2	16849327
Pubmed	The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer.	PTPRK ZNRF3	1.82e-05	2	149	2	31934854
Pubmed	The mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressor.	BCOR MLLT3	1.82e-05	2	149	2	12776190
Pubmed	Tie-1: A potential target for anti-angiogenesis therapy.	TEK TIE1	1.82e-05	2	149	2	26489611
Pubmed	RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13.	PEBP1 MMP13	1.82e-05	2	149	2	26308852
Pubmed	PTPRK, an EGFR Phosphatase, Is Decreased in CeD Biopsies and Intestinal Organoids.	PTPRK EGFR	1.82e-05	2	149	2	36611909
Pubmed	An interaction between insulin-like growth factor-binding protein 2 (IGFBP2) and integrin alpha5 is essential for IGFBP2-induced cell mobility.	ITGA5 IGFBP2	1.82e-05	2	149	2	16569642
Pubmed	A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.	TEK TIE1	1.82e-05	2	149	2	1312667
Pubmed	Redifferentiation and ZO-1 reexpression in liver-metastasized colorectal cancer: possible association with epidermal growth factor receptor-induced tyrosine phosphorylation of ZO-1.	EGFR TJP1	1.82e-05	2	149	2	12708492
Pubmed	Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks.	RAG1 DICER1	1.82e-05	2	149	2	23427252
Pubmed	Murine LRBA deficiency causes CTLA-4 deficiency in Tregs without progression to immune dysregulation.	RAG1 LRBA	1.82e-05	2	149	2	28611475
Pubmed	Defective Zn2+ homeostasis in mouse and human platelets with α- and δ-storage pool diseases.	UNC13D NBEAL2	1.82e-05	2	149	2	31171812
Pubmed	Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.	ADAMTS8 TEK TIE1 MMP13	2.13e-05	38	149	4	18267097
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	DDX17 ABLIM1 ATXN2 TJP1 AMOT G3BP2 PLEC PTCD3	2.56e-05	274	149	8	34244482
Pubmed	Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation.	RAG1 NOG SMAD1	2.71e-05	14	149	3	12421925
Pubmed	Tie1 is required for lymphatic valve and collecting vessel development.	LAMA5 TEK TIE1	2.71e-05	14	149	3	25576926
Pubmed	Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.	POTEF NBEA SEC24C RAB11FIP5	2.90e-05	41	149	4	34638806
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	DPY19L1 BAG3 SLC35E1 ABLIM1 OSBP GANAB EGFR ATXN2 TJP1 GLE1 AMOT G3BP2 RBM7 RAB11FIP5 LRBA	3.01e-05	1007	149	15	34597346
Pubmed	MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.	BAG3 GPX7 DICER1 IGFBP2 SULT4A1 SMAD1	3.27e-05	140	149	6	20819778
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	DDX17 SLC35E1 DICER1 EGFR ATXN2 GLE1 G3BP2 FBXO41 ASCC3 MED12	3.28e-05	462	149	10	31138677
Pubmed	The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation.	LAMA5 TJP1 SMAD1	4.14e-05	16	149	3	19733164
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA5 LAMC3 TJP1	4.14e-05	16	149	3	17601529
Pubmed	Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.	LAMA5 TEK TIE1	4.14e-05	16	149	3	28179430
Pubmed	Large-scale structural analysis of the classical human protein tyrosine phosphatome.	TEK TIE1 PTPRK EGFR	5.00e-05	47	149	4	19167335
Pubmed	Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.	EPPK1 DDX17 GANAB ATXN2 HELZ2 PLEC	5.18e-05	152	149	6	16009940
Pubmed	The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.	NBEA LRBA	5.45e-05	3	149	2	28814779
Pubmed	Tie1 regulates the Tie2 agonistic role of angiopoietin-2 in human lymphatic endothelial cells.	TEK TIE1	5.45e-05	3	149	2	22342979
Pubmed	IGFBP2 potentiates nuclear EGFR-STAT3 signaling.	IGFBP2 EGFR	5.45e-05	3	149	2	25893308
Pubmed	Analysis of the status of EGFR, ROS1 and MET genes in non-small cell lung adenocarcinoma.	EGFR ROS1	5.45e-05	3	149	2	28952227
Pubmed	Ligand-independent Tie2 dimers mediate kinase activity stimulated by high dose angiopoietin-1.	TEK TIE1	5.45e-05	3	149	2	23504320
Pubmed	Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.	TEK TIE1	5.45e-05	3	149	2	17728252
Pubmed	Comparable clinical outcomes in patients with HER2-mutant and EGFR-mutant lung adenocarcinomas.	EGFR ROS1	5.45e-05	3	149	2	28063177
Pubmed	Prognostic significance of co-overexpression of the EGFR/IGFBP-2/HIF-2A genes in astrocytomas.	IGFBP2 EGFR	5.45e-05	3	149	2	17285230
Pubmed	Clinical characteristics of non-small cell lung cancer patients with EGFR mutations and ALK&ROS1 fusions.	EGFR ROS1	5.45e-05	3	149	2	35081265
Pubmed	PD-L1 expression in ROS1-rearranged non-small cell lung cancer: A study using simultaneous genotypic screening of EGFR, ALK, and ROS1.	EGFR ROS1	5.45e-05	3	149	2	30475455
Pubmed	Transforming growth factor {beta} (TGF-{beta})-Smad target gene protein tyrosine phosphatase receptor type kappa is required for TGF-{beta} function.	PTPRK EGFR	5.45e-05	3	149	2	15899872
Pubmed	Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development.	TEK TIE1	5.45e-05	3	149	2	10498691
Pubmed	Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases.	UNC13D NBEAL2	5.45e-05	3	149	2	27079884
Pubmed	Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6.	ETV6 EGFR	5.45e-05	3	149	2	27746161
Pubmed	High prevalence of ROS1 gene rearrangement detected by FISH in EGFR and ALK negative lung adenocarcinoma.	EGFR ROS1	5.45e-05	3	149	2	32979347
Pubmed	Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis.	TJP1 AMOT	5.45e-05	3	149	2	19590046
Pubmed	MicroRNA-155 drives TH17 immune response and tissue injury in experimental crescentic GN.	RAG1 DICER1	5.45e-05	3	149	2	23949802
Pubmed	A Human IgSF Cell-Surface Interactome Reveals a Complex Network of Protein-Protein Interactions.	TEK TIE1	5.45e-05	3	149	2	32822567
Pubmed	Activation of Bmp2-Smad1 signal and its regulation by coordinated alteration of H3K27 trimethylation in Ras-induced senescence.	NOG SMAD1	5.45e-05	3	149	2	22072987
Pubmed	Integrin α5β1-Ang1/Tie2 receptor cross-talk regulates brain endothelial cell responses following cerebral ischemia.	ITGA5 TEK	5.45e-05	3	149	2	30185785
Pubmed	The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells.	TEK TIE1	5.45e-05	3	149	2	26344773
Pubmed	A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling.	PTPRK ZNRF3	5.45e-05	3	149	2	34590584
Pubmed	Integrin α(5) interacts with EGFR, is necessary for FcɛRI signaling and is necessary for allergic inflammation in relation with angiogenesis.	ITGA5 EGFR	5.45e-05	3	149	2	21349584
Pubmed	The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome.	MAP3K14 EGFR	5.45e-05	3	149	2	11116146
Pubmed	EGFR mutations and ROS1 and ALK rearrangements in a large series of non-small cell lung cancer in South India.	EGFR ROS1	5.45e-05	3	149	2	32881404
Pubmed	Activated protein C enhances human keratinocyte barrier integrity via sequential activation of epidermal growth factor receptor and Tie2.	TEK EGFR	5.45e-05	3	149	2	21173154
Interaction	ANGPT1 interactions	ITGA5 TEK TIE1 TJP1	4.62e-06	16	147	4	int:ANGPT1
Cytoband	2q21.1	POTEF POTEKP POTEE POTEI	3.94e-05	58	149	4	2q21.1
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEF POTEKP POTEE POTEI	6.83e-07	13	103	4	685
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEA NBEAL2 LRBA	1.47e-05	9	103	3	1230
GeneFamily	Acid sensing ion channel subunits	ASIC1 ASIC4	3.18e-04	5	103	2	290
GeneFamily	WD repeat domain containing	KIF21A APAF1 NBEA DMXL1 NBEAL2 IFT80 LRBA	7.52e-04	262	103	7	362
GeneFamily	EF-hand domain containing\|Plakins	EPPK1 PLEC	8.80e-04	8	103	2	939
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	TEK TIE1 ROS1	1.52e-03	40	103	3	321
GeneFamily	X-linked mental retardation\|RNA helicases	DICER1 ASCC3	1.71e-03	11	103	2	1168
GeneFamily	Laminin subunits	LAMA5 LAMC3	2.04e-03	12	103	2	626
GeneFamily	Fibronectin type III domain containing	FNDC3B TEK TIE1 PTPRK ROS1	2.22e-03	160	103	5	555
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS8 ADAMTS7	5.16e-03	19	103	2	50
Coexpression	GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_UP	IKZF2 NOG ASIC1 GCNT2 ITGA5 IGFBP2 GUCY1B1 MLLT3 ZC3H12C	1.75e-06	195	148	9	M8006
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_ACTC_POS_SMC_CELL	FRAS1 NOG LAMA5 ETV6 ARMC9 ADAMTS8 GCNT2 ITGA5 HOXC4 OXCT1 IGFBP2 CSRNP3 SLMAP STK38L	6.69e-06	589	148	14	M45662
Coexpression	LAKE_ADULT_KIDNEY_C6_PROXIMAL_TUBULE_EPITHELIAL_CELLS_FIBRINOGEN_POS_S3	KIF21A HLA-E DICER1 PTPRK PEBP1 PNRC1 ASCC3 FGGY	9.16e-06	181	148	8	M39225
Coexpression	XU_GH1_AUTOCRINE_TARGETS_DN	SLC22A23 LAMA5 NBEA SETD2 PTPRK TJP1 RBM7	9.87e-06	131	148	7	M16384
Coexpression	GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP	CBLL1 KIF21A BAG3 SPIRE1 SAMSN1 ZNRF3 ZC3H12C	1.45e-05	139	148	7	M11672
Coexpression	GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP	SPIRE1 NBEA SIK3 TJP1 PPM1L ANKIB1 PIP5K1B MLLT3	1.89e-05	200	148	8	M7489
Coexpression	SIMBULAN_UV_RESPONSE_NORMAL_DN	FAT2 EGFR PLEC MN1	3.52e-05	33	148	4	M16114
Coexpression	LAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE	FNDC3B FRAS1 SPIRE1 SIK3 MLLT3 LRBA CSGALNACT1	5.49e-05	171	148	7	M39234
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	SLC22A23 KIF21A RNF44 CEP76 DICER1 DMBX1 ZNF503 NCOR1 SETD2 OXCT1 GUCY1B1 PPM1L SLMAP ANKIB1 MLLT3 CFAP74 AK4 ZC3H12C IFT80 LRBA	1.08e-05	989	143	20	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	Fetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2	RAG1 IKZF2 DLGAP5 ETV6 NBEA GCNT2 SAMSN1 TEK HMCN1 TIE1 TJP1 MLLT3	2.23e-05	410	143	12	GSM791122_500
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000	APAF1 NBEA NCOR1 CSRNP3 EGFR LRRTM4 RAB11FIP5 MLLT3 MN1 SMAD1	2.64e-05	288	143	10	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlas	Fetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2	RAG1 IKZF2 GCNT2 TEK HMCN1 TIE1	2.71e-05	87	143	6	GSM791122_100
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD3 LAMC3 TEK TIE1 GUCY1B1 PIP5K1B CFAP74 AK4	1.51e-07	178	148	8	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	LAMA5 UNC13D GCNT2 ABLIM1 EGFR TJP1 NBEAL2 RP1	1.94e-07	184	148	8	561592edc3083fad41b91811151b442207c65dd9
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	LAMA5 UNC13D GCNT2 ABLIM1 TJP1 NBEAL2 RP1 ZC3H12C	2.11e-07	186	148	8	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC22A23 ABLIM1 SHC2 HMCN1 TIE1 RAB11FIP5 CSGALNACT1 SMAD1	2.48e-07	190	148	8	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEK IGFBP2 HMCN1 TIE1 PTPRK TJP1 CSGALNACT1 SMAD1	2.91e-07	194	148	8	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	SLC22A23 LAMA5 ABLIM1 EGFR TJP1 PNRC1 RP1	1.66e-06	170	148	7	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 GCNT2 PTPRK MLLT3 ROS1 RP1 LRBA	2.34e-06	179	148	7	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LAMA5 UNC13D GCNT2 ABLIM1 NBEAL2 PIP5K1B ZC3H12C	2.81e-06	184	148	7	29c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA5 GCNT2 ABLIM1 EGFR TJP1 NBEAL2 RP1	2.91e-06	185	148	7	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFSF12 INPP5K GPX7 LAMA5 ZNF407 NBEA CSGALNACT1	2.91e-06	185	148	7	60206c7322b4ddb2010040aac70561df842c9843
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 IKZF2 SLC22A23 KIF21A EGFR ZNRF3 IFT80	3.01e-06	186	148	7	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	BAG3 ITGA5 TEK ABLIM1 TIE1 TJP1 CSGALNACT1	3.23e-06	188	148	7	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	ASK428-Endothelial-Lymphatic\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	HLA-E TEK SHC2 TIE1 RAB11FIP5 AK4 SMAD1	3.23e-06	188	148	7	c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D FNDC3B FRAS1 HMCN1 PIP5K1B LRBA CSGALNACT1	3.35e-06	189	148	7	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK ABLIM1 IGFBP2 HMCN1 TIE1 CSGALNACT1	3.35e-06	189	148	7	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D FNDC3B FRAS1 HMCN1 PIP5K1B LRBA CSGALNACT1	3.35e-06	189	148	7	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 GCNT2 ADCY8 PTPRK ZNRF3 ROS1 LRBA	3.47e-06	190	148	7	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK ABLIM1 HMCN1 TIE1 SAMD11 RP1	3.47e-06	190	148	7	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 TEK TIE1 TJP1 PPM1L ZC3H12C CSGALNACT1	3.47e-06	190	148	7	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK IGFBP2 TIE1 PPM1L ZC3H12C CSGALNACT1	3.47e-06	190	148	7	a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK ABLIM1 IGFBP2 HMCN1 TIE1 HMGCLL1	3.72e-06	192	148	7	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK IGFBP2 HMCN1 TIE1 CSGALNACT1 SMAD1	3.72e-06	192	148	7	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Vein\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK ABLIM1 IGFBP2 HMCN1 SAMD11 HMGCLL1	3.72e-06	192	148	7	717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK IGFBP2 TIE1 TJP1 CSGALNACT1 SMAD1	3.85e-06	193	148	7	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEK IGFBP2 HMCN1 TIE1 TJP1 CSGALNACT1 SMAD1	3.85e-06	193	148	7	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 ITGA5 TEK TIE1 FAM124A RP1 CSGALNACT1	3.85e-06	193	148	7	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK STAB1 ABLIM1 HMCN1 TIE1 HMGCLL1	3.85e-06	193	148	7	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK IGFBP2 TIE1 TJP1 ZC3H12C CSGALNACT1	3.98e-06	194	148	7	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK IGFBP2 TIE1 TJP1 ZC3H12C CSGALNACT1	3.98e-06	194	148	7	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SLC22A23 GCNT2 PTPRK EGFR PIP5K1B ROS1 LRBA	4.12e-06	195	148	7	9406866f99555198a9be311fbd65751b70f35446
ToppCell	ASK428-Endothelial\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	HLA-E TEK STAB1 SHC2 TIE1 RAB11FIP5 SMAD1	4.55e-06	198	148	7	d69d0ff115298596173a4278897a65007a71f5df
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	FRAS1 UNC13D HMCN1 TIE1 ZNRF3 TJP1 PLEC	4.70e-06	199	148	7	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	FNDC3B ETV6 ZNF407 NBEA SIK3 MLLT3 LRBA	4.70e-06	199	148	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / Treatment groups by lineage, cell group, cell type	BAG3 TEK STAB1 ABLIM1 TIE1 PLEC SMAD1	4.86e-06	200	148	7	b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IKZF2 SLC22A23 NBEA GCNT2 ABLIM1 PTPRK PPM1L	4.86e-06	200	148	7	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	FNDC3B TEK STAB1 HMCN1 TIE1 PLEC HMGCLL1	4.86e-06	200	148	7	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	TCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-7\|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9	IKZF2 GUCY1B1 PIP5K1B MLLT3 LRBA MN1	9.13e-06	145	148	6	88090a226ddfa6df59976f025bf0fd84ca0f72ef
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CACNA1D ZNF805 TIE1 HELZ2 AK4 ASCC3	1.44e-05	157	148	6	4183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCell	Control\|World / group, cell type (main and fine annotations)	SLC22A23 IQCN PTPRK EGFR PIP5K1B ROS1	2.11e-05	168	148	6	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 LAMA5 FAT2 IGFBP2 EGFR MMP13	2.11e-05	168	148	6	6521bead9789d626b86cbd08692c621c5a5aef33
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEK STAB1 HMCN1 TIE1 CSGALNACT1 HMGCLL1	2.11e-05	168	148	6	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRERF1 MAP3K14 SPIRE1 GCNT2 SAMSN1 GVINP1	2.11e-05	168	148	6	27cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEK STAB1 HMCN1 TIE1 CSGALNACT1 HMGCLL1	2.11e-05	168	148	6	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MOGAT2 FOXN4 KIF21A IQCN CFAP74 ASIC4	2.18e-05	169	148	6	606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MOGAT2 FOXN4 KIF21A IQCN CFAP74 ASIC4	2.18e-05	169	148	6	052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 LAMA5 FAT2 IGFBP2 EGFR MMP13	2.18e-05	169	148	6	c3ee781735a9288ce1822b230d39bb91c1415589
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCNT2 DICER1 STAB1 HMCN1 NIPAL2 CSGALNACT1	2.41e-05	172	148	6	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCNT2 DICER1 STAB1 HMCN1 NIPAL2 CSGALNACT1	2.41e-05	172	148	6	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SIK3 SAMSN1 TEK TIE1 NIPAL2 UBE2W	2.41e-05	172	148	6	8a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1\|TCGA-Liver / Sample_Type by Project: Shred V9	FRAS1 UNC13D ARMC9 PCNX2 TMEM132A MLLT3	2.92e-05	178	148	6	51c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 LAMA5 GCNT2 PTPRK EGFR PIP5K1B	3.01e-05	179	148	6	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	HLA-E ITGA5 TEK HMCN1 TIE1 FAM124A	3.01e-05	179	148	6	040a7e916baaf81f44339dc721ab2afcd2c22388
ToppCell	Epithelial-basal_cell\|World / Lineage, Cell type, age group and donor	FRAS1 LAMA5 FAT2 IGFBP2 EGFR LPA	3.01e-05	179	148	6	d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	APAF1 ZNF805 ABLIM1 AMOT IFT80 CSGALNACT1	3.11e-05	180	148	6	9f4bbaf6435c23e3e552ae22be8ea7884314192d
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	APAF1 ZNF805 ABLIM1 AMOT IFT80 CSGALNACT1	3.11e-05	180	148	6	b465f2f8b0e9a2034a4f1272bb00c77439164dbf
ToppCell	BAL-Severe-Lymphocyte-B-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	APAF1 ZNF805 ABLIM1 AMOT IFT80 CSGALNACT1	3.11e-05	180	148	6	c3c72531af5b9f7a7416727fe609dab5180e03b6
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCNT2 TEK ABLIM1 TIE1 RP1 PLEC	3.30e-05	182	148	6	e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCNT2 TEK ABLIM1 TIE1 RP1 PLEC	3.30e-05	182	148	6	ccc313ecc0bfd8e2c6bb83a565b427b2310485ec
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCNT2 TEK ABLIM1 TIE1 RP1 PLEC	3.30e-05	182	148	6	b9f758961fb4a586ae86fa0b25edb8ce4616d644
ToppCell	Adult-Epithelial-basal_cell\|Adult / Lineage, Cell type, age group and donor	FRAS1 FAT2 IGFBP2 HMCN1 EGFR LPA	3.41e-05	183	148	6	00a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADCY8 PTPRK EGFR ZNRF3 PIP5K1B ROS1	3.41e-05	183	148	6	6847c1252d6bb105524f812658112517fd351eab
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGA5 TEK TIE1 FAM124A RP1 CSGALNACT1	3.51e-05	184	148	6	842473fa415575441b595073a994b6d621169776
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EGFR LRRTM4 PIP5K1B ROS1 MN1 CSGALNACT1	3.51e-05	184	148	6	30fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EGFR LRRTM4 PIP5K1B ROS1 MN1 CSGALNACT1	3.51e-05	184	148	6	96926efa220f03d0787322c9519bb9e8f64f74d0
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF2 YIPF2 FAT2 IGFBP2 NBEAL2 ILDR1	3.51e-05	184	148	6	382b1e90b3f437af596750669c0465a169d97095
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D GCNT2 ABLIM1 PPM1L RP1 LRBA	3.62e-05	185	148	6	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D GCNT2 OXCT1 PPM1L RP1 LRBA	3.73e-05	186	148	6	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	Control-Epithelial-Club\|World / Disease state, Lineage and Cell class	GCNT2 PTPRK EGFR TJP1 MLLT3 ROS1	3.73e-05	186	148	6	9798428691408e17ff2af2fe2d1b345f074d67e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D GCNT2 OXCT1 PPM1L RP1 LRBA	3.73e-05	186	148	6	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LAMC3 NBEA GUCY1B1 TJP1 LRRTM4 MLLT3	3.84e-05	187	148	6	fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 LAMA5 UNC13D GCNT2 NBEAL2 RP1	3.84e-05	187	148	6	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ASIC1 PCNX2 SHC2 G3BP2 LRRTM4 SULT4A1	3.84e-05	187	148	6	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	AT1_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	FRAS1 LAMA5 UNC13D ABLIM1 NBEAL2 HMGCLL1	3.84e-05	187	148	6	f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	GCNT2 PTPRK MLLT3 ROS1 RP1 LRBA	3.84e-05	187	148	6	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA5 ABLIM1 EGFR TJP1 NBEAL2 ZC3H12C	3.84e-05	187	148	6	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CACNA1D FNDC3B SLC22A23 PTPRK PIP5K1B LRBA	3.84e-05	187	148	6	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	LAMA5 UNC13D GCNT2 ABLIM1 TJP1 NBEAL2	3.84e-05	187	148	6	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK IGFBP2 TIE1 CSGALNACT1 SMAD1	3.84e-05	187	148	6	dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	SLC22A23 FAT2 IGFBP2 PTPRK EGFR MMP13	3.84e-05	187	148	6	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEK ZNF503 STAB1 TIE1 TJP1 FAM124A	3.96e-05	188	148	6	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SLC22A23 PTPRK EGFR PIP5K1B ROS1 RP1	3.96e-05	188	148	6	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC22A23 TEK HMCN1 TIE1 CSGALNACT1 SMAD1	3.96e-05	188	148	6	2db80767903703e7e0a1a37c598f7877a909ee94
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D GCNT2 HMCN1 PIP5K1B RP1 LRBA	4.08e-05	189	148	6	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK IGFBP2 HMCN1 TIE1 CSGALNACT1	4.08e-05	189	148	6	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEK ZNF503 STAB1 TIE1 TJP1 FAM124A	4.20e-05	190	148	6	a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-E SAMSN1 TEK ABLIM1 TIE1 CSGALNACT1	4.20e-05	190	148	6	92fdfed12061ee9f6c7171cf8a7f3344921f2d40
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BAG3 ITGA5 TEK TIE1 TJP1 CSGALNACT1	4.20e-05	190	148	6	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B FRAS1 KIF21A GCNT2 ZNRF3 RP1	4.20e-05	190	148	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEK ZNF503 STAB1 TIE1 TJP1 FAM124A	4.20e-05	190	148	6	25525fee1da8a808034d9c916159fd0b6b26bce8
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA5 GCNT2 TJP1 NBEAL2 PIP5K1B RP1	4.20e-05	190	148	6	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM IKZF2 ETV6 SAMSN1 NBEAL2 LRBA	4.32e-05	191	148	6	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 ADAMTS8 GUCY1B1 PPM1L SLMAP STK38L	4.32e-05	191	148	6	8e8beb8e8a3b33cac83d3f7ce915a71e3654fdab
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D GCNT2 ABLIM1 PPM1L RP1 LRBA	4.32e-05	191	148	6	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-leukocyte\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 SLC22A23 KIF21A SAMSN1 SEPSECS ILDR1	4.32e-05	191	148	6	116fba9badea093e11f370996247cca0e4c02e8f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 GCNT2 ADCY8 EGFR PIP5K1B MN1	4.32e-05	191	148	6	7b386512284dfaa0e95358b28ee82632ee965e64
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GCNT2 PTPRK EGFR ZNRF3 PIP5K1B RP1	4.32e-05	191	148	6	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 ADAMTS8 FAT2 GUCY1B1 PPM1L SLMAP	4.32e-05	191	148	6	60bc1f3efa7bbad5cb7944fe5e049ea79cd1745a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 GCNT2 ADCY8 EGFR PIP5K1B MN1	4.32e-05	191	148	6	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	GCNT2 PTPRK EGFR ZNRF3 PIP5K1B ROS1	4.45e-05	192	148	6	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	LPS-IL1RA+antiTNF-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 TEK IGFBP2 TIE1 TJP1 CSGALNACT1	4.45e-05	192	148	6	04f5a2e3dd6beff027b89d66eefdd92036e041af
Disease	acute kidney tubular necrosis (biomarker_via_orthology)	NOG TEK AK4	1.06e-06	5	141	3	DOID:12556 (biomarker_via_orthology)
Disease	mammographic density percentage	NBEA ADAMTS8 ADCY8 GVINP1	1.08e-05	29	141	4	EFO_0006502
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	APAF1 TEK SETD2 PEBP1 AP5M1 RIOK2	8.08e-05	148	141	6	C0279702
Disease	Adrenocortical carcinoma	EGFR ZNRF3 MED12	8.27e-05	18	141	3	C0206686
Disease	mammographic density measurement	NBEA ADAMTS8 ADCY8 GVINP1	9.70e-05	50	141	4	EFO_0005941
Disease	white matter microstructure measurement	EPPK1 RTP2 UNC13D ARMC9 TIE1 EGFR ATXN2 PLEC FGGY	1.13e-04	390	141	9	EFO_0005674
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	MOGAT2 SIK3 ATXN2 LPA CSGALNACT1	1.39e-04	103	141	5	EFO_0008595, EFO_0020944
Disease	Malignant Cystosarcoma Phyllodes	SETD2 MED12	2.25e-04	5	141	2	C0600066
Disease	Phyllodes Tumor	SETD2 MED12	2.25e-04	5	141	2	C0010701
Disease	Antihypertensive use measurement	CACNA1D BAG3 ADCY8 HOXC4 ZNRF3 ATXN2 LRBA	2.96e-04	265	141	7	EFO_0009927
Disease	electroencephalogram measurement	FNDC3B PCNX2 PTPRK MLLT3	4.44e-04	74	141	4	EFO_0004357
Disease	lobe attachment	NBEA SIK3 ADCY8 HMCN1 LRBA MN1	4.95e-04	207	141	6	EFO_0007667
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	MOGAT2 SIK3 ATXN2 LPA HELZ2 CSGALNACT1 SMAD1	5.18e-04	291	141	7	EFO_0008317, EFO_0020946
Disease	Embryonal Rhabdomyosarcoma	BCOR SETD2	6.23e-04	8	141	2	C0206656
Disease	right ventricular systolic volume measurement	BAG3 ATXN2 PLEC	6.25e-04	35	141	3	EFO_0021815
Disease	Mitral valve prolapse	BAG3 ATXN2 MN1	6.79e-04	36	141	3	HP_0001634
Disease	mean arterial pressure	CACNA1D HOXC4 ZNRF3 ATXN2 GUCY1B1 SLMAP RAB11FIP5 LRBA STK38L	6.87e-04	499	141	9	EFO_0006340
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	MOGAT2 ATXN2 LPA HELZ2 LRBA CSGALNACT1	7.14e-04	222	141	6	EFO_0008317, EFO_0020943
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	ATXN2 LPA HELZ2 LRBA CSGALNACT1 SMAD1	7.66e-04	225	141	6	EFO_0008317, EFO_0020947
Disease	sexual dimorphism measurement	FNDC3B MGAM EPPK1 NOG TNFSF12 ASIC1 GPX7 ETV6 SIK3 ADCY8 LPA AVIL PLEC CSGALNACT1	8.67e-04	1106	141	14	EFO_0021796
Disease	platelet glycoprotein ib alpha chain measurement	ATXN2 AK4	9.95e-04	10	141	2	EFO_0020645
Disease	cholesteryl esters to total lipids in small LDL percentage	MOGAT2 SIK3 LPA	1.07e-03	42	141	3	EFO_0022255
Disease	mean fractional anisotropy measurement	EPPK1 TIE1 EGFR PLEC	1.14e-03	95	141	4	EFO_0008399
Disease	total cholesterol measurement, intermediate density lipoprotein measurement	MOGAT2 MOSPD3 ATXN2 LPA	1.32e-03	99	141	4	EFO_0004574, EFO_0008595
Disease	peptic esophagitis (biomarker_via_orthology)	EGFR TJP1	1.45e-03	12	141	2	DOID:13976 (biomarker_via_orthology)
Disease	Secondary Open Angle Glaucoma	FNDC3B ATXN2	1.45e-03	12	141	2	C0271148
Disease	N-delta-acetylornithine measurement	FBXO41 RAB11FIP5	1.45e-03	12	141	2	EFO_0800067
Disease	Glaucoma, Open-Angle	FNDC3B ATXN2	1.45e-03	12	141	2	C0017612
Disease	blood urea nitrogen measurement	IKZF2 EGFR ATXN2 PIP5K1B ILDR1 LRBA ASCC3 HMGCLL1	1.53e-03	452	141	8	EFO_0004741
Disease	tonsillectomy risk measurement	HLA-E GPX7 ZNF407 NBEA SEPSECS ATXN2	1.61e-03	260	141	6	EFO_0007924
Disease	Glaucoma, Primary Open Angle	FNDC3B ATXN2	1.71e-03	13	141	2	C0339573
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	MOGAT2 ATXN2 LPA HELZ2 CSGALNACT1 SMAD1	1.74e-03	264	141	6	EFO_0008317, EFO_0020944
Disease	polyunsaturated fatty acids to monounsaturated fatty acids ratio	SIK3 LPA CSGALNACT1	1.88e-03	51	141	3	EFO_0022302
Disease	linoleic acid measurement	MOGAT2 SIK3 ATXN2 LPA LRRTM4	2.04e-03	186	141	5	EFO_0006807
Disease	platelet crit	TNFSF12 MAP3K14 HLA-E LAMA5 ZNF407 EGFR ATXN2 LPA AK4 RP1 PLEC MN1	2.11e-03	952	141	12	EFO_0007985
Disease	HMG CoA reductase inhibitor use measurement	SETD2 GUCY1B1 LPA RP1 PLEC	2.19e-03	189	141	5	EFO_0009932
Disease	waist-hip ratio	FNDC3B NOG MAP3K14 CUL9 ZNF407 IQCN SIK3 ADCY8 STAB1 HOXC4 ZNRF3 ATXN2 AK4 MN1	2.27e-03	1226	141	14	EFO_0004343
Disease	multiple sclerosis	IKZF2 EPPK1 MAP3K14 ETV6 ADCY8 SEPSECS PTPRK ATXN2 PLEC	2.28e-03	594	141	9	MONDO_0005301
Disease	gamma-glutamylphenylalanine measurement	SAMSN1 TEK	2.29e-03	15	141	2	EFO_0021142
Disease	FEV/FEC ratio	CACNA1D FNDC3B MGAM FRAS1 NOG BAG3 ETV6 ADCY8 PRR12 HOXC4 HMCN1 SLMAP MN1 PTCD3	2.31e-03	1228	141	14	EFO_0004713
Disease	vital capacity	NOG TNFSF12 MAP3K14 UNC13D ADAMTS8 ADCY8 NCOR1 HMCN1 LRRTM4 SLMAP AP5M1 ASIC4 LRBA HMGCLL1	2.45e-03	1236	141	14	EFO_0004312
Disease	free cholesterol to total lipids in medium VLDL percentage	SIK3 ATXN2 LPA	2.59e-03	57	141	3	EFO_0022284
Disease	infantile hypertrophic pyloric stenosis	SIK3 SLMAP	2.60e-03	16	141	2	EFO_0004707
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	MOGAT2 ATXN2 LPA CSGALNACT1	2.76e-03	121	141	4	EFO_0008595, EFO_0020943
Disease	colorectal cancer (is_implicated_in)	BCOR DICER1 SETD2 EGFR	2.76e-03	121	141	4	DOID:9256 (is_implicated_in)
Disease	Prostatic Neoplasms	RAG1 UNC13D ADAMTS8 NCOR1 SETD2 PTPRK EGFR MMP13 MED12	2.91e-03	616	141	9	C0033578
Disease	Malignant neoplasm of prostate	RAG1 UNC13D ADAMTS8 NCOR1 SETD2 PTPRK EGFR MMP13 MED12	2.91e-03	616	141	9	C0376358
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	IKZF2 ETV6 SETD2	3.14e-03	61	141	3	C1961102
Disease	free cholesterol in HDL measurement	MOGAT2 SIK3 LPA	3.14e-03	61	141	3	EFO_0022264
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	MOGAT2 ATXN2 LPA CSGALNACT1	3.28e-03	127	141	4	EFO_0008595, EFO_0020947
Disease	maximum cigarettes per day measurement	ADCY8 EGFR	3.30e-03	18	141	2	EFO_0009264
Disease	Sarcomatoid Renal Cell Carcinoma	APAF1 SETD2 PEBP1 AP5M1	3.37e-03	128	141	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	APAF1 SETD2 PEBP1 AP5M1	3.37e-03	128	141	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	APAF1 SETD2 PEBP1 AP5M1	3.37e-03	128	141	4	C1266044
Disease	esterified cholesterol measurement	MOGAT2 SIK3 ATXN2 LPA	3.37e-03	128	141	4	EFO_0008589
Disease	Papillary Renal Cell Carcinoma	APAF1 SETD2 PEBP1 AP5M1	3.37e-03	128	141	4	C1306837
Disease	Renal Cell Carcinoma	APAF1 SETD2 PEBP1 AP5M1	3.37e-03	128	141	4	C0007134
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	MOGAT2 BAG3 SIK3 ATXN2 LPA CSGALNACT1	3.44e-03	303	141	6	EFO_0004612, EFO_0020945
Disease	choline measurement	MOGAT2 SIK3 ATXN2 LPA	3.56e-03	130	141	4	EFO_0010116
Disease	polyunsaturated fatty acid measurement	MOGAT2 SIK3 ATXN2 LPA	3.66e-03	131	141	4	EFO_0010733
Disease	acetone measurement	OXCT1 AK4	3.68e-03	19	141	2	EFO_0010989
Disease	Central precocious puberty	C1orf141 PAX3	3.68e-03	19	141	2	EFO_0009029
Disease	acetate measurement	ATXN2 AK4	4.07e-03	20	141	2	EFO_0010112
Disease	Deaf Mutism	CACNA1D PAX3	4.07e-03	20	141	2	C4082305
Disease	Deafness, Acquired	CACNA1D PAX3	4.07e-03	20	141	2	C0751068
Disease	Hearing Loss, Extreme	CACNA1D PAX3	4.07e-03	20	141	2	C0086395
Disease	Complete Hearing Loss	CACNA1D PAX3	4.07e-03	20	141	2	C0581883
Disease	corneal hysteresis	FNDC3B ADAMTS8	4.07e-03	20	141	2	EFO_0010066
Disease	Bilateral Deafness	CACNA1D PAX3	4.07e-03	20	141	2	C3665473
Disease	Prelingual Deafness	CACNA1D PAX3	4.07e-03	20	141	2	C0011052
Disease	non-word reading	LAMC3 RAB11FIP5 MLLT3	4.09e-03	67	141	3	EFO_0005299
Disease	stroke, coronary artery disease	ADAMTS7 LPA	4.49e-03	21	141	2	EFO_0000712, EFO_0001645
Disease	gastric ulcer (biomarker_via_orthology)	TEK MMP13	4.49e-03	21	141	2	DOID:10808 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PGHYEFTQVHNLPES	C2orf16	1251	Q68DN1
YCVSGLPEPRQDHAH	ADCY8	466	P40145
RYHQPHTLSPDQEDC	APAF1	466	O14727
PPSQEHYQSQRDIFH	ERVPABLB-1	496	P60509
RLAPQHHFPAQFEDG	AADACL2	146	Q6P093
PQEPGHFYSEHRLNQ	AMOT	256	Q4VCS5
QQYLHTHPSGRDPDT	AVIL	676	O75366
RFSSHPLENENIYPH	C1orf141	226	Q5JVX7
YGHHDAVPPLEQQLV	CSGALNACT1	396	Q8TDX6
HFHVPDQGINIYRKP	ABLIM1	511	O14639
NQPSDRHPEHYDTAI	ADAMTS8	301	Q9UP79
HTVPIYEGNALPHAT	POTEKP	161	Q9BYX7
DYDLFLHLEGHPPVN	MLLT3	101	P42568
DHSVPFHRPQAVNGE	GVINP1	2306	Q7Z2Y8
PTGYQRPLQSALHHV	APCDD1L	236	Q8NCL9
GEPYQHNTPLHYAAR	ANKIB1	41	Q9P2G1
PYGNRQEIHPHGLNH	GLE1	586	Q53GS7
LTGHRYIHKPTNPDE	CEP76	426	Q8TAP6
ITKHLYEDPRQHSPG	DICER1	1716	Q9UPY3
GNPVDSHAYPHIQNS	BCOR	296	Q6W2J9
ALVAHTGYLPHQQDP	DMXL1	326	Q9Y485
LEIHGGPPQNYIASH	DMXL1	2541	Q9Y485
GHAQPHVVYKRQAPE	ADAMTS7	176	Q9UKP4
DEHNRRYPVHGPVDG	RAG1	121	P15918
GPGEHDQVYPDAAQH	QRICH2	916	Q9H0J4
SHIYNEEPQGPVRHR	RAB11FIP5	341	Q9BXF6
GDIPYHAPQQVRFQH	IQCN	161	Q9H0B3
PRPHQENNHQESYPL	ETV6	221	P41212
HTVPIYEGNALPHAT	POTEF	861	A5A3E0
TYHHIIRLFDQPGDP	PTCD3	371	Q96EY7
QRYTCHVQHEGLPEP	HLA-E	276	P13747
HPHSPIRYFTQEDIN	FRAS1	1521	Q86XX4
DQPVIGYCQAHQPLH	LRRTM4	531	Q86VH4
PPDHAVGRTKYVHQE	GCNT2	221	Q8N0V5
YNLDFNPPHVHGIDD	AK4	136	P27144
NGHPQALPAAHEAVY	ARMC9	681	Q7Z3E5
QHPHVYSPVIQGNAR	ATXN2	1061	Q99700
LPDGSPVQHYNVHNL	MGAM	2366	O43451
NSLYPEHRSNHPQVE	CSRNP3	516	Q8WYN3
HHTEQVHGRFLPYLP	FAM124A	131	Q86V42
DPASPIHGHNQIITY	PCNX2	891	A6NKB5
PSRFHQYQQHRPSLE	PNRC1	111	Q12796
EDGNLHPPRFTQLHY	FAT2	1546	Q9NYQ8
ERGPLEHLYSLHIPN	IGFBP2	246	P18065
PNRIDAAYEHPSHDL	MMP13	331	P45452
PPHERVHHPDYNNEL	PDZD11	26	Q5EBL8
PQHPLHVTYAGAAVD	PEBP1	21	P30086
VNEHYPHDRPTLYSN	PIP5K1B	486	O14986
HHYPDFHQELQDRGP	ILDR1	371	Q86SU0
ALRPIVNHPHYEDAG	DPY19L1	566	Q2PZI1
QNIREGHYPEPAHLS	PLK5	21	Q496M5
GHYPEPAHLSANARR	PLK5	26	Q496M5
HNLPAHQGAVQDQPY	LRBA	2551	P50851
VDNPHGEIYHPQSRC	LMLN2	506	A0A1B0GTW7
DPTRHLQQRPSGYVH	MED12	1986	Q93074
PTALRHYLDNHGPAA	GDPD3	301	Q7L5L3
ENSDPQFHLEHRGPV	GUCY1B1	576	Q02153
AHIPFYNRGPITHLE	AP5M1	356	Q9H0R1
HSQEEPPYIHQLGFG	ASIC4	256	Q96FT7
YPTPGHVHRGQLQLV	LAMA5	1751	O15230
VSHHRVGETAPPNAY	DDOST	311	P39656
DHQSYQGHPALNPKR	IKZF2	416	Q9UKS7
NGYRSLCEQVSHHPP	OSBP	511	P22059
YDLSVHAPPSIIGNH	HMCN1	2376	Q96RW7
LTNHGGVPHQPQTDY	PAX3	396	P23760
EHYNQPHEDIRAPPA	CBLL1	251	Q75N03
ELDPSRNYIAGFHPH	MOGAT2	96	Q3SYC2
HTVPIYEGNALPHAT	POTEE	861	Q6S8J3
APVDSHGLRPALHYQ	ITGA5	616	P08648
PNVAHHLGRAAYIQP	CCDC105	56	Q8IYK2
RDPHYQDPHSTAVGN	EGFR	1121	P00533
DSYGRPLYNSQPHEH	IFT80	216	Q9P2H3
LGPQTYRHAEREHPE	BCLAF3	256	A2AJT9
FHPLPVNQEGDSHRN	FGGY	96	Q96C11
PVPAHEPSHRYDDQA	CCDC9	306	Q9Y3X0
AQHAPDYRPSVHALT	DMBX1	31	Q8NFW5
FPQHHLPHTIYGEQE	FNDC3B	156	Q53EP0
RYPDSHQLFVGNLPH	G3BP2	326	Q9UN86
PPHISNNYQRLEHFD	INPP5K	151	Q9BT40
RESGFQHHHQELYPP	HOXC4	41	P09017
PHHGVPYFRNILQSE	DLGAP5	426	Q15398
HRHQRTPENYPNDGL	LPA	1646	P08519
HVGPAVPNTYAVSRH	FBXO41	381	Q8TF61
YPEELIRQRPGHDGH	CUL9	21	Q8IWT3
IRQRPGHDGHPEYLI	CUL9	26	Q8IWT3
VHINHQPYLERGDGP	DDX17	231	Q92841
VPYGSLQLAEHPHAL	HELZ2	1771	Q9BYK8
QRDLGPHHFNVLAFP	GPX7	71	Q96SL4
EGAENRQVHPFHVYP	BAG3	101	O95817
VPPQYFQHLDHTGKR	SEC24C	456	P53992
FQHRRPDLYGNLGHP	NIT1	311	Q86X76
LVSPYHTHRAGDPLD	C1orf50	41	Q9BV19
PLSHRQDYELQDFGP	CACNA1D	2121	Q01668
RAVGVHPPLELSHYQ	CFAP74	1011	Q9C0B2
DYAQQIGVPEHPDVH	PRDM4	531	Q9UKN5
RPSHYIATQGPVHET	PTPRK	951	Q15262
NYHQTLHAQPRELSP	MAP3K14	681	Q99558
GGQHYLHIRPAPSDN	NOG	26	Q13253
PDFPEAIAHHSIQNY	RP1	901	P56715
PSQHAQFEYPIHRLE	MN1	401	Q10571
VRYPVLTPNLQGFHH	HMGCLL1	146	Q8TB92
NSGQNHHPSPQEYRL	FOXN4	16	Q96NZ1
QYRIHVASRPDSGPH	RTP2	136	Q5QGT7
APQDVSLSYPQHHVG	RBM7	91	Q9Y580
AHRTEFYRNLTHNPP	STK38L	241	Q9Y2H1
PEHFRVQQVGHYPPA	TMEM132A	56	Q24JP5
SNGEHYTRQPLLPHK	SLC22A23	631	A1A5C7
AHPYRNSDPVIGTHT	SAMSN1	101	Q9NSI8
SHLQLAQQEHPRPYF	NIPAL2	71	Q9H841
YGSVPVLLAHNPHRD	GANAB	296	Q14697
IGYPHLQEVLQSHGP	NBEAL2	406	Q6ZNJ1
RHHIIGDNPNSSDYP	NBEA	2756	Q8NFP9
AGEVYRSHLPTHLDP	NCOR1	1556	O75376
DPVHSHRVPVDVAYQ	EPPK1	2886	P58107
DGNAIPLSHDHKPYQ	PPM1L	221	Q5SGD2
AQELGIHPYGHQPTA	SIK3	1146	Q9Y2K2
EDPQRLYHLGLPSHG	SAMD11	206	Q96NU1
HTVPIYDGNALPHAT	POTEI	861	P0CG38
GPYPRQHEADADLIN	OXCT1	351	P55809
ETDILHRQAYAAPHP	PRR12	41	Q9ULL5
EKPHNGLLFPQHGDY	SLC35E1	366	Q96K37
PRHSEYNPQHSLLAQ	SMAD1	141	Q15797
ANILPHHPARGTFED	ASIC1	511	P78348
PLEVHIQGFPGQHYC	ASCC3	1521	Q8N3C0
PLIQHQRTHTGEKPY	ZNF135	396	P52742
HLPYRFLPSDLHNGD	SULT4A1	111	Q9BR01
PPDHEEHLYVNTQGL	SHC2	406	P98077
HNFEPPHYDGIEALT	KIF21A	1536	Q7Z4S6
VIYVHNSPGAHLLPD	TIE1	116	P35590
HLPTESDAPNHYQAV	SPIRE1	206	Q08AE8
RPNSHPFQERHVYLD	SLMAP	11	Q14BN4
HDPLHQELSFGVPYS	RNF44	256	Q7L0R7
IRHVAPIPSHYDVQD	MOSPD3	96	O75425
YNHSGQPEVNHVPLE	STAB1	1221	Q9NY15
TLGHQPYPAHSNLDV	ROS1	2156	P08922
VHLPHAQPQDAGVYS	TEK	176	Q02763
NEGIAHLRQYLHLPP	PLEC	76	Q15149
INGYPLCQIHHVEDP	RIOK2	191	Q9BVS4
SQNRLQPFPHGYHEA	ZC3H12B	621	Q5HYM0
QPFPHGYHEALTRVQ	ZC3H12B	626	Q5HYM0
APYDHAQPLVGHSTE	SETD2	2201	Q9BYW2
RHEEQPAPGYDTHGR	TJP1	1156	Q07157
TARTGHILHPEYLQP	ZNF503	81	Q96F45
GAHQRSHFEPERPYQ	ZXDA	376	P98168
QGLYGLHPDHLPRTD	ZNRF3	756	Q9ULT6
SEAYNERLLHTPHNP	SEPSECS	356	Q9HD40
AIAAHYEVHPRPGQD	TNFSF12	106	O43508
ENIPVHPHVYSNGHI	UBE2W	76	Q96B02
HDPLTRGQSYSHEEP	ZC3H12C	681	Q9C0D7
HPDIENPDLAYLHAG	ZNF407	1796	Q9C0G0
AQRRDPSIHYSPQFH	YIPF2	146	Q9BWQ6
YTVLHRLGHPEPNHV	UNC13D	61	Q70J99
HHILQQDAPFGPEDY	PPIP5K1	636	Q6PFW1
VPRPELIYHLEHGQE	ZNF805	56	Q5CZA5
ALGHHNPSYPVARAQ	PP6455	21	Q8WZ26
HVAHGSENLFYQQPP	TRERF1	11	Q96PN7
EAPRGDVYQGHHLLP	LAMC3	1056	Q9Y6N6