Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	2.80e-06	5	132	3	GO:0030156
GeneOntologyMolecularFunction	calcium ion binding	PRSS1 PRSS2 COMP DSC3 CALML3 PCLO PCDHB5 PCDHB6 LRP1B TENM2 LRP8 THBD THBS2 THBS4 FBN1 LRP1 RASEF	9.17e-06	749	132	17	GO:0005509
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1B LRP8 LRP1	1.48e-04	16	132	3	GO:0005041
GeneOntologyMolecularFunction	cargo receptor activity	LRP1B CD163 LRP8 LRP1 SCARA3	2.51e-04	85	132	5	GO:0038024
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1B LRP8 LRP1	3.44e-04	21	132	3	GO:0030228
GeneOntologyMolecularFunction	scavenger receptor activity	CD163 LRP1 SCARA3	7.35e-04	27	132	3	GO:0005044
HumanPheno	Limited elbow extension	FLNB COMP PTH1R FBN1 MED12 PCNT	1.53e-05	60	47	6	HP:0001377
HumanPheno	Abnormal periauricular region morphology	FLNB NAA10 CHD7 KMT2D LRP1 RERE CTNND2 MED12	2.09e-05	131	47	8	HP:0000383
HumanPheno	Abnormal cheek morphology	FLNB PCLO NAA10 CHD7 KMT2D FBN1 LRP1 RERE CTNND2 MED12 PCNT	3.59e-05	282	47	11	HP:0004426
HumanPheno	Abnormal metaphysis morphology	FLNB COMP RTEL1 ARX CHD7 PTH1R FBN1 LPIN2 RERE COG4 MED12 PCNT	4.49e-05	344	47	12	HP:0000944
HumanPheno	Flared metaphysis	FLNB COMP ARX PTH1R FBN1 RERE COG4 MED12 PCNT	4.80e-05	191	47	9	HP:0003015
Domain	EGF	COMP LRP1B TENM2 LRP8 THBD THBS2 THBS4 FBN1 NRXN3 MALRD1 TENM4 LRP1	7.80e-08	235	128	12	SM00181
Domain	EGF_3	COMP LRP1B TENM2 LRP8 THBD THBS2 THBS4 FBN1 NRXN3 MALRD1 TENM4 LRP1	7.80e-08	235	128	12	PS50026
Domain	EGF_CA	COMP LRP1B LRP8 THBD THBS2 THBS4 FBN1 LRP1	1.32e-07	86	128	8	PF07645
Domain	EGF-like_dom	COMP LRP1B TENM2 LRP8 THBD THBS2 THBS4 FBN1 NRXN3 MALRD1 TENM4 LRP1	1.46e-07	249	128	12	IPR000742
Domain	EGF_CA	COMP LRP1B TENM2 LRP8 THBD THBS2 THBS4 FBN1 LRP1	1.60e-07	122	128	9	SM00179
Domain	EGF-like_Ca-bd_dom	COMP LRP1B TENM2 LRP8 THBD THBS2 THBS4 FBN1 LRP1	1.84e-07	124	128	9	IPR001881
Domain	EGF_1	COMP LRP1B TENM2 LRP8 THBD THBS2 THBS4 FBN1 NRXN3 MALRD1 TENM4 LRP1	1.89e-07	255	128	12	PS00022
Domain	EGF-like_CS	COMP LRP1B TENM2 LRP8 THBD THBS2 THBS4 FBN1 NRXN3 MALRD1 TENM4 LRP1	2.43e-07	261	128	12	IPR013032
Domain	-	LRP1B TENM2 LRP8 TENM4 LRP1 ROS1	2.50e-07	39	128	6	2.120.10.30
Domain	EGF_2	COMP LRP1B TENM2 LRP8 THBD THBS2 THBS4 FBN1 NRXN3 MALRD1 TENM4 LRP1	2.86e-07	265	128	12	PS01186
Domain	6-blade_b-propeller_TolB-like	LRP1B TENM2 LRP8 TENM4 LRP1 ROS1	6.89e-07	46	128	6	IPR011042
Domain	EGF	LRP1B LRP8 THBD THBS2 THBS4 NRXN3 MALRD1 LRP1	2.49e-06	126	128	8	PF00008
Domain	LY	LRP1B LRP8 LRP1 ROS1	2.71e-06	15	128	4	SM00135
Domain	LDLR_classB_rpt	LRP1B LRP8 LRP1 ROS1	2.71e-06	15	128	4	IPR000033
Domain	TSP_3	COMP THBS2 THBS4	3.11e-06	5	128	3	PF02412
Domain	TSP3	COMP THBS2 THBS4	3.11e-06	5	128	3	PS51234
Domain	TSP_CTER	COMP THBS2 THBS4	3.11e-06	5	128	3	PS51236
Domain	Thrombospondin_3_rpt	COMP THBS2 THBS4	3.11e-06	5	128	3	IPR017897
Domain	TSP_type-3_rpt	COMP THBS2 THBS4	3.11e-06	5	128	3	IPR028974
Domain	-	COMP THBS2 THBS4	3.11e-06	5	128	3	4.10.1080.10
Domain	Thrombospondin_C	COMP THBS2 THBS4	3.11e-06	5	128	3	IPR008859
Domain	TSP_C	COMP THBS2 THBS4	3.11e-06	5	128	3	PF05735
Domain	Thrombospondin_3-like_rpt	COMP THBS2 THBS4	3.11e-06	5	128	3	IPR003367
Domain	EGF_Ca-bd_CS	COMP LRP1B LRP8 THBD THBS4 FBN1 LRP1	4.64e-06	97	128	7	IPR018097
Domain	EGF_CA	COMP LRP1B LRP8 THBD THBS4 FBN1 LRP1	5.31e-06	99	128	7	PS01187
Domain	cEGF	LRP1B THBD FBN1 LRP1	2.80e-05	26	128	4	PF12662
Domain	cEGF	LRP1B THBD FBN1 LRP1	2.80e-05	26	128	4	IPR026823
Domain	DUF5050	LRP1B LRP1	4.66e-05	2	128	2	IPR032485
Domain	DUF5050	LRP1B LRP1	4.66e-05	2	128	2	PF16472
Domain	ASX_HYDROXYL	LRP1B LRP8 THBD FBN1 NRXN3 LRP1	6.49e-05	100	128	6	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP1B LRP8 THBD FBN1 NRXN3 LRP1	8.98e-05	106	128	6	IPR000152
Domain	Growth_fac_rcpt_	COMP LRP1B LRP8 THBD THBS4 FBN1 LRP1	1.01e-04	156	128	7	IPR009030
Domain	Ldl_recept_b	LRP1B LRP8 LRP1	1.08e-04	14	128	3	PF00058
Domain	LDLRB	LRP1B LRP8 LRP1	1.08e-04	14	128	3	PS51120
Domain	Rhs_assc_core	TENM2 TENM4	1.39e-04	3	128	2	IPR022385
Domain	COMP	COMP THBS4	1.39e-04	3	128	2	PF11598
Domain	Thbs/COMP_coiled-coil	COMP THBS4	1.39e-04	3	128	2	IPR024665
Domain	RGS	MYH9 RGS9 RGS3 RGS12	1.44e-04	39	128	4	IPR016137
Domain	LDLR_class-A_CS	LRP1B LRP8 MALRD1 LRP1	1.59e-04	40	128	4	IPR023415
Domain	Ldl_recept_a	LRP1B LRP8 MALRD1 LRP1	2.52e-04	45	128	4	PF00057
Domain	-	LRP1B LRP8 MALRD1 LRP1	2.75e-04	46	128	4	4.10.400.10
Domain	Tox-GHH_dom	TENM2 TENM4	2.77e-04	4	128	2	IPR028916
Domain	Tox-GHH	TENM2 TENM4	2.77e-04	4	128	2	PF15636
Domain	Ten_N	TENM2 TENM4	2.77e-04	4	128	2	IPR009471
Domain	Ten_N	TENM2 TENM4	2.77e-04	4	128	2	PF06484
Domain	TENEURIN_N	TENM2 TENM4	2.77e-04	4	128	2	PS51361
Domain	LDLRA_1	LRP1B LRP8 MALRD1 LRP1	3.24e-04	48	128	4	PS01209
Domain	LDrepeatLR_classA_rpt	LRP1B LRP8 MALRD1 LRP1	3.51e-04	49	128	4	IPR002172
Domain	LDLa	LRP1B LRP8 MALRD1 LRP1	3.51e-04	49	128	4	SM00192
Domain	LDLRA_2	LRP1B LRP8 MALRD1 LRP1	3.51e-04	49	128	4	PS50068
Domain	TRYPSIN_SER	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	3.86e-04	90	128	5	IPR033116
Domain	-	RGS9 RGS3 RGS12	4.40e-04	22	128	3	1.10.196.10
Domain	RGS_subdom1	RGS9 RGS3 RGS12	4.40e-04	22	128	3	IPR024066
Domain	YD	TENM2 TENM4	4.60e-04	5	128	2	IPR006530
Domain	-	PAPPA2 COMP THBS2 THBS4 NRXN3	4.95e-04	95	128	5	2.60.120.200
Domain	TRYPSIN_HIS	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	7.16e-04	103	128	5	IPR018114
Domain	TRYPSIN_SER	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	8.15e-04	106	128	5	PS00135
Domain	TRYPSIN_HIS	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	8.50e-04	107	128	5	PS00134
Domain	GoLoco	PCP2 RGS12	9.57e-04	7	128	2	SM00390
Domain	GoLoco	PCP2 RGS12	9.57e-04	7	128	2	PF02188
Domain	GoLoco_motif	PCP2 RGS12	9.57e-04	7	128	2	IPR003109
Domain	GOLOCO	PCP2 RGS12	9.57e-04	7	128	2	PS50877
Domain	Peptidase_S1A	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	1.09e-03	113	128	5	IPR001314
Domain	TRYPSIN_DOM	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	1.18e-03	115	128	5	PS50240
Domain	Tryp_SPc	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	1.27e-03	117	128	5	SM00020
Domain	IQ	MYH9 MYO6 IQSEC2 MYO15A	1.43e-03	71	128	4	PF00612
Domain	Trypsin_dom	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	1.47e-03	121	128	5	IPR001254
Domain	Trypsin	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	1.47e-03	121	128	5	PF00089
Domain	Peptidase_S1_PA	PRSS1 PRSS2 PRSS41 TMPRSS11E KLK5	1.58e-03	123	128	5	IPR009003
Domain	RGS	RGS9 RGS3 RGS12	1.75e-03	35	128	3	PF00615
Domain	RGS	RGS9 RGS3 RGS12	1.75e-03	35	128	3	SM00315
Domain	RGS	RGS9 RGS3 RGS12	1.90e-03	36	128	3	PS50132
Domain	Myosin_head_motor_dom	MYH9 MYO6 MYO15A	2.23e-03	38	128	3	IPR001609
Domain	MYOSIN_MOTOR	MYH9 MYO6 MYO15A	2.23e-03	38	128	3	PS51456
Domain	Myosin_head	MYH9 MYO6 MYO15A	2.23e-03	38	128	3	PF00063
Domain	MYSc	MYH9 MYO6 MYO15A	2.23e-03	38	128	3	SM00242
Domain	SH3_2	RIMBP3 RIMBP3C MYO15A RIMBP3B	2.90e-03	86	128	4	PF07653
Domain	SH3_2	RIMBP3 RIMBP3C MYO15A RIMBP3B	2.90e-03	86	128	4	IPR011511
Domain	IQ_motif_EF-hand-BS	MYH9 MYO6 IQSEC2 MYO15A	3.41e-03	90	128	4	IPR000048
Domain	NHL	TENM2 TENM4	3.46e-03	13	128	2	PS51125
Domain	SH3	DLG5 ABL2 RIMBP3 RIMBP3C MYO15A RIMBP3B	3.76e-03	216	128	6	SM00326
Domain	SH3	DLG5 ABL2 RIMBP3 RIMBP3C MYO15A RIMBP3B	3.76e-03	216	128	6	PS50002
Domain	IQ	MYH9 MYO6 IQSEC2 MYO15A	3.84e-03	93	128	4	PS50096
Domain	PDZ	DLG5 SYNPO2 PCLO RGS3 RGS12	3.86e-03	151	128	5	PS50106
Domain	PDZ	DLG5 SYNPO2 PCLO RGS3 RGS12	3.97e-03	152	128	5	IPR001478
Domain	PLAC	ADAMTS19 ADAMTS17	4.02e-03	14	128	2	PF08686
Domain	ConA-like_dom	PAPPA2 COMP THBS2 THBS4 NRXN3 MALRD1	4.02e-03	219	128	6	IPR013320
Domain	SH3_domain	DLG5 ABL2 RIMBP3 RIMBP3C MYO15A RIMBP3B	4.11e-03	220	128	6	IPR001452
Domain	OAR	ARX SHOX2	4.62e-03	15	128	2	PF03826
Domain	OAR	ARX SHOX2	5.25e-03	16	128	2	PS50803
Domain	OAR_dom	ARX SHOX2	5.25e-03	16	128	2	IPR003654
Domain	CarboxyPept-like_regulatory	TENM2 TENM4	5.93e-03	17	128	2	IPR008969
Pubmed	Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.	PRSS1 PRSS2 PRSS3P2	5.34e-08	3	132	3	11073713
Pubmed	The origin of trypsin: evidence for multiple gene duplications in trypsins.	PRSS1 PRSS2 PRSS3P2	5.34e-08	3	132	3	9732462
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	FLNB MYH9 HK2 CNST PCLO IQSEC2 SUN1 SANBR GRIA1 MARCKSL1 LRP1B TENM2 SRPRB CEP170 NHSL1 TENM4 KCTD16 AKT2 CTNND2	6.61e-08	1139	132	19	36417873
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FLNB MYH9 TTC28 CHD7 GREB1L KMT2D ZFHX4 ZNF608 LRP1 RERE MED12 PCNT	7.40e-08	418	132	12	34709266
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 PDE3B ABL2 TTC28 KIF26B IQSEC2 NAA10 N4BP3 TRIP12 RGS12 C6orf132 CEP170 NHSL1 BOD1L1 RNF180 DOP1A	1.88e-07	861	132	16	36931259
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	2.13e-07	4	132	3	19091768
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AKAP6 FLNB TTC28 MYO6 CNST IQSEC2 NAP1L2 TRIP12 LRP1B POLR3B FBN1 OSBPL1A LRP1 MIGA1 ANKRD24 CTNND2 COG4 USP47 PCNT	4.19e-07	1285	132	19	35914814
Pubmed	Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.	COMP THBS2 THBS4	5.31e-07	5	132	3	30622267
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	5.31e-07	5	132	3	17855024
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	AKAP6 TTC28 RTEL1 CHD7 TLK1 TENM4 ZNF608 PCNT	2.51e-06	225	132	8	12168954
Pubmed	Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.	COMP THBS2 THBS4	2.95e-06	8	132	3	24460873
Pubmed	Reduced polyalanine-expanded Arx mutant protein in developing mouse subpallium alters Lmo1 transcriptional regulation.	ARX SHOX2 GRIA1	2.95e-06	8	132	3	24122442
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	ELOB FLNB MYH9 TTC28 MYO6 CALML3 BMS1 N4BP3 TRIP12 SRPRB USP19 POLR3B RTCA LRP1 USP47	6.83e-06	1005	132	15	19615732
Pubmed	USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.	FLNB MYH9 USP19	8.62e-06	11	132	3	19015242
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	ELOB PRSS1 FLNB PPFIBP2 PCLO BMS1 STXBP3 PCNT	1.15e-05	277	132	8	30745168
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB PDE3B MYO6 RTEL1 PPFIBP2 LRP8 CEP170 TLK1 ZNF608 SLC16A14 LRP1 RASEF BOD1L1 ANKRD24 RERE SCARA3 DOP1A PCNT	1.41e-05	1489	132	18	28611215
Pubmed	Striking differences of LDL receptor-related protein 1B expression in mouse and human.	LRP1B LRP1	1.43e-05	2	132	2	15963947
Pubmed	Differential glycosylation regulates processing of lipoprotein receptors by gamma-secretase.	LRP8 LRP1	1.43e-05	2	132	2	12871934
Pubmed	Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations.	PRSS1 PRSS3P2	1.43e-05	2	132	2	11702203
Pubmed	CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions.	CHD7 KMT2D	1.43e-05	2	132	2	28475860
Pubmed	Histone methyltransferase MLL4 protects against pressure overload-induced heart failure via a THBS4-mediated protection in ER stress.	THBS4 KMT2D	1.43e-05	2	132	2	38876442
Pubmed	Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression.	PRSS1 PRSS2	1.43e-05	2	132	2	36191639
Pubmed	Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population.	THBS2 THBS4	1.43e-05	2	132	2	27160021
Pubmed	Exome sequencing identified new mutations in a Marfan syndrome family.	FBN1 LRP1	1.43e-05	2	132	2	24484584
Pubmed	A novel ADAMTS17 variant that causes Weill-Marchesani syndrome 4 alters fibrillin-1 and collagen type I deposition in the extracellular matrix.	FBN1 ADAMTS17	1.43e-05	2	132	2	31726086
Pubmed	Role of the Common PRSS1-PRSS2 Haplotype in Alcoholic and Non-Alcoholic Chronic Pancreatitis: Meta- and Re-Analyses.	PRSS1 PRSS2	1.43e-05	2	132	2	33202925
Pubmed	COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens.	COMP THBS4	1.43e-05	2	132	2	30464261
Pubmed	Increased cortical expression of two synaptogenic thrombospondins in human brain evolution.	THBS2 THBS4	1.43e-05	2	132	2	17182969
Pubmed	Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.	PRSS1 PRSS2	1.43e-05	2	132	2	20484960
Pubmed	Precocious chondrocyte differentiation disrupts skeletal growth in Kabuki syndrome mice.	SHOX2 KMT2D	1.43e-05	2	132	2	31557133
Pubmed	Low-density lipoprotein receptor-related protein 1 (LRP1) regulates the stability and function of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor in neurons.	GRIA1 LRP1	1.43e-05	2	132	2	25500815
Pubmed	Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis.	PRSS1 PRSS3P2	1.43e-05	2	132	2	25546417
Pubmed	Plasminogen-dependent internalization of soluble melanotransferrin involves the low-density lipoprotein receptor-related protein and annexin II.	MELTF LRP1	1.43e-05	2	132	2	17570828
Pubmed	Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.	PRSS1 PRSS2	1.43e-05	2	132	2	27846138
Pubmed	Biophysical characterization of the signature domains of thrombospondin-4 and thrombospondin-2.	THBS2 THBS4	1.43e-05	2	132	2	16246837
Pubmed	Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).	PRSS1 PRSS2	1.43e-05	2	132	2	14695529
Pubmed	Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.	PRSS1 PRSS2	1.43e-05	2	132	2	15776435
Pubmed	AKT2 phosphorylation of hexokinase 2 at T473 promotes tumorigenesis and metastasis in colon cancer cells via NF-κB, HIF1α, MMP2, and MMP9 upregulation.	HK2 AKT2	1.43e-05	2	132	2	30877036
Pubmed	Variants within the COMP and THBS2 genes are not associated with Achilles tendinopathy in a case-control study of South African and Australian populations.	COMP THBS2	1.43e-05	2	132	2	23875975
Pubmed	Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.	PRSS1 PRSS2	1.43e-05	2	132	2	18461367
Pubmed	Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.	PRSS1 PRSS2	1.43e-05	2	132	2	15651064
Pubmed	Immunoreactive anionic and cationic trypsin in human serum.	PRSS1 PRSS2	1.43e-05	2	132	2	2598466
Pubmed	Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.	PRSS1 PRSS2	1.43e-05	2	132	2	35089416
Pubmed	Trypsinogen copy number mutations in patients with idiopathic chronic pancreatitis.	PRSS1 PRSS2	1.43e-05	2	132	2	18063422
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	1.89e-05	14	132	3	17662146
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	ELOB FLNB MYH9 BMS1 STXBP3 NOM1 RPS10P5	1.92e-05	215	132	7	35973513
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TTC28 TENM2 USP19 TENM4 PER2 PLEKHM2 BOD1L1 RERE PCNT	2.69e-05	407	132	9	12693553
Pubmed	Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia.	SHOX2 HOXA11 TENM4	3.50e-05	17	132	3	15944189
Pubmed	Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.	RGS9 RGS3 RGS12	3.50e-05	17	132	3	20627871
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNB MYH9 BMS1 CHD7 TRIP12 DNTTIP2 CEP170 UTP20 MED12 USP47 PCNT	4.18e-05	653	132	11	22586326
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS19 FBN1 ADAMTS17	4.18e-05	18	132	3	35503090
Pubmed	Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.	PRSS1 PRSS2	4.28e-05	3	132	2	24146905
Pubmed	Interaction of soluble CD163 with activated T lymphocytes involves its association with non-muscle myosin heavy chain type A.	MYH9 CD163	4.28e-05	3	132	2	15479433
Pubmed	Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes.	THBS2 THBS4	4.28e-05	3	132	2	15121769
Pubmed	Trypsin-mediated enzymatic degradation of type II collagen in the human vitreous.	PRSS1 PRSS2	4.28e-05	3	132	2	23882137
Pubmed	Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).	CHD7 KMT2D	4.28e-05	3	132	2	28007623
Pubmed	Coexpression of CD163 and CD141 identifies human circulating IL-10-producing dendritic cells (DC-10).	CD163 THBD	4.28e-05	3	132	2	30842629
Pubmed	Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer.	COMP THBS4	4.28e-05	3	132	2	33910854
Pubmed	Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.	COMP THBS2	4.28e-05	3	132	2	26168731
Pubmed	Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.	THBS2 THBS4	4.28e-05	3	132	2	25976449
Pubmed	Association of claudin2 and PRSS1-PRSS2 polymorphisms with idiopathic recurrent acute and chronic pancreatitis: A case-control study from India.	PRSS1 PRSS2	4.28e-05	3	132	2	26110235
Pubmed	Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.	THBS2 THBS4	4.28e-05	3	132	2	18178577
Pubmed	Involvement of the Apoer2 and Lrp1 receptors in mediating the pathological effects of ApoE4 in vivo.	LRP8 LRP1	4.28e-05	3	132	2	24251389
Pubmed	Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling.	THBS2 LRP1	4.28e-05	3	132	2	20472562
Pubmed	Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.	THBS2 THBS4	4.28e-05	3	132	2	12482844
Pubmed	Divergent roles of SPINK1 and PRSS2 variants in tropical calcific pancreatitis.	PRSS1 PRSS2	4.28e-05	3	132	2	19077465
Pubmed	CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestion.	PRSS1 PRSS2	4.28e-05	3	132	2	1763044
Pubmed	Novel myosin mutations for hereditary hearing loss revealed by targeted genomic capture and massively parallel sequencing.	MYO6 MYO15A	4.28e-05	3	132	2	24105371
Pubmed	Soluble Receptors Affecting Stroke Outcomes: Potential Biomarkers and Therapeutic Tools.	CD163 LRP1	4.28e-05	3	132	2	33498620
Pubmed	Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2'.	LRP8 LRP1	4.28e-05	3	132	2	12807892
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	AKAP6 MYO6 N4BP3 PER2 ZNF646	4.97e-05	104	132	5	9205841
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	ELOB PDE3B HK2 TTC28 MYO6 PCLO SUN1 BMS1 PEX6 SRPRB USP19 NOM1 NFX1 MIGA1 RERE USP47 PCNT	5.39e-05	1496	132	17	32877691
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP1B LRP8 LRP1	6.76e-05	21	132	3	21337463
Pubmed	mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors.	PCP2 GRIA1	8.54e-05	4	132	2	30190524
Pubmed	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.	TENM2 TENM4	8.54e-05	4	132	2	10225957
Pubmed	Myo15 function is distinct from Myo6, Myo7a and pirouette genes in development of cochlear stereocilia.	MYO6 MYO15A	8.54e-05	4	132	2	12966030
Pubmed	Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study.	PRSS1 PRSS2	8.54e-05	4	132	2	25253127
Pubmed	Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.	THBS2 THBS4	8.54e-05	4	132	2	6338048
Pubmed	Cloning and developmental expression of nonmuscle myosin IIA (Myh9) in the mammalian inner ear.	MYH9 MYO6	8.54e-05	4	132	2	15079858
Pubmed	Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.	PRSS1 PRSS2	8.54e-05	4	132	2	33515547
Pubmed	Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.	MYO6 MYO15A	8.54e-05	4	132	2	22105175
Pubmed	Weill-Marchesani Syndrome	FBN1 ADAMTS17	8.54e-05	4	132	2	20301293
Pubmed	Histiocytic sarcoma: New insights into FNA cytomorphology and molecular characteristics.	CD163 KMT2D	8.54e-05	4	132	2	28805986
Pubmed	Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens.	PRSS1 PRSS2	8.54e-05	4	132	2	3011602
Pubmed	All four members of the Ten-m/Odz family of transmembrane proteins form dimers.	TENM2 TENM4	8.54e-05	4	132	2	12000766
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	FLNB DLG5 MYH9 ABL2 DSC3 TTC28 MYO6 SRPRB CEP170 BOD1L1 MED12	8.59e-05	708	132	11	39231216
Pubmed	Functional proteomics mapping of a human signaling pathway.	PAPPA2 FLNB MYO6 PEX6 BCAT1 TRIP12 RGS3 KMT2D NOM1 LRP1	9.10e-05	591	132	10	15231748
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	FLNB MYO6 NAA10 TRIP12 SRPRB USP19 NFX1 USP47 PCNT	9.71e-05	481	132	9	28190767
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ELOB DLG5 ABL2 TTC28 LRP1B RGS12 RIMBP3 STXBP3 NFX1 RASEF USP47 PCNT	1.04e-04	853	132	12	28718761
Pubmed	Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.	AKAP6 ELOB MARCKSL1 TRIP12 CEP170 MED12	1.05e-04	195	132	6	17110338
Pubmed	A human MAP kinase interactome.	SYNPO2 MYH9 ABL2 MYO6 KIF26B MKNK2 TLK1 ANKRD24 COG4	1.05e-04	486	132	9	20936779
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FLNB MYH9 PDE3B KIF26B PCLO IQSEC2 BMS1 TRIP12 THBS4 UTP20 BOD1L1	1.21e-04	736	132	11	29676528
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLNB MYH9 MYO6 BMS1 TRIP12 UTP20	1.27e-04	202	132	6	33005030
Pubmed	PRSS1-Related Hereditary Pancreatitis	PRSS1 PRSS2	1.42e-04	5	132	2	22379635
Pubmed	Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.	COMP THBS4	1.42e-04	5	132	2	18467703
Pubmed	ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.	LRP8 LRP1	1.42e-04	5	132	2	16101684
Pubmed	Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo.	LRP1 AKT2	1.42e-04	5	132	2	24126057
Pubmed	Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells.	MYH9 MYO6	1.42e-04	5	132	2	17615572
Pubmed	PPARγ contributes to PKM2 and HK2 expression in fatty liver.	HK2 AKT2	1.42e-04	5	132	2	22334075
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	RTEL1 FBN1 TENM4 LRP1	1.58e-04	71	132	4	33541421
GeneFamily	Low density lipoprotein receptors	LRP1B LRP8 LRP1	2.49e-05	13	82	3	634
GeneFamily	Regulators of G-protein signaling	RGS9 RGS3 RGS12	1.13e-04	21	82	3	720
GeneFamily	Proteases, serine	PRSS1 PRSS2 PRSS41 TMPRSS11E	1.91e-04	63	82	4	738
GeneFamily	PDZ domain containing	DLG5 SYNPO2 PCLO RGS3 RGS12	6.37e-04	152	82	5	1220
GeneFamily	DNA helicases	RTEL1 CHD7	2.64e-03	17	82	2	1167
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS19 ADAMTS17	3.30e-03	19	82	2	50
Coexpression	GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN	HK2 ABL2 PPFIBP2 BCAT1 MARCKSL1 GREB1L MEX3A LPIN2 CTNND2	8.27e-07	200	132	9	M304
Coexpression	HAY_BONE_MARROW_STROMAL	SYNPO2 MYO6 PCDHB5 PCDHB6 TENM2 RGS3 PTH1R THBS2 FBN1 NRXN3 TENM4 ZFHX4 C11orf96 RNF180 SCARA3	7.77e-06	767	132	15	M39209
CoexpressionAtlas	kidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_500	TTC28 KIF26B CHD7 HOXA11 MEX3A ADAMTS17 RASEF SCARA3	3.00e-05	196	131	8	gudmap_kidney_P1_CapMes_Crym_k4_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#1_top-relative-expression-ranked_100	NIBAN1 SYNPO2 CD163	4.85e-05	12	131	3	gudmap_developingLowerUrinaryTract_P1_bladder_J_100_k1
CoexpressionAtlas	kidney_P1_CapMes_Crym_top-relative-expression-ranked_500	TTC28 KIF26B CHD7 HOXA11 MEX3A LPIN2 ADAMTS17 RASEF SCARA3	5.52e-05	276	131	9	gudmap_kidney_P1_CapMes_Crym_500
CoexpressionAtlas	BM Top 100 - saphenous vein	NIBAN1 SYNPO2 COMP SHOX2 C11orf96	6.78e-05	69	131	5	BM Top 100 - saphenous vein
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#5_top-relative-expression-ranked_200	KIF26B SHOX2 ZFHX4 RNF180	7.80e-05	37	131	4	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_200	AKAP6 SYNPO2 KIF26B NAP1L2 SHOX2 ZFHX4 RNF180	8.09e-05	167	131	7	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200
CoexpressionAtlas	kidney_P1_CapMes_Crym_top-relative-expression-ranked_200	TTC28 KIF26B CHD7 HOXA11 LPIN2 RASEF	1.01e-04	120	131	6	gudmap_kidney_P1_CapMes_Crym_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_200	SYNPO2 DSC3 KIF26B NAP1L2 SHOX2 ZFHX4 RNF180	1.08e-04	175	131	7	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000	AKAP6 PAPPA2 SYNPO2 DSC3 KIF26B WNT6 SHOX2 LRP1B TENM2 CRHBP PTH1R HOXA11 THBD FBN1 CFAP52 ZFHX4 KCTD16	1.33e-04	994	131	17	PCBC_ratio_EB_vs_SC_1000
CoexpressionAtlas	kidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_100	TTC28 KIF26B HOXA11 RASEF	1.42e-04	43	131	4	gudmap_kidney_P1_CapMes_Crym_k4_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_100	SYNPO2 DSC3 KIF26B SHOX2 ZFHX4	1.83e-04	85	131	5	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_100	NIBAN1 SYNPO2 CRHBP THBS4 ZFHX4	1.93e-04	86	131	5	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_100
CoexpressionAtlas	kidney_P0_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500	TTC28 KIF26B CHD7 HOXA11 ADAMTS17 RASEF SCARA3	2.05e-04	194	131	7	gudmap_kidney_P0_CapMes_Crym_k2_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_1000	KIF26B NAP1L2 TENM2 LRP8 CEP170 ZFHX4 RNF180	2.18e-04	196	131	7	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_1000
CoexpressionAtlas	kidney_P3_CapMes_Crym_top-relative-expression-ranked_1000	PDE3B TTC28 MYO6 KIF26B PCLO CHD7 HOXA11 FBN1 MEX3A TENM4 ZNF608 LPIN2 RASEF SCARA3	2.21e-04	749	131	14	gudmap_kidney_P3_CapMes_Crym_1000
CoexpressionAtlas	JC_fibro_top-relative-expression-ranked_500	AKAP6 PAPPA2 SYNPO2 COMP KIF26B SHOX2 GRIA1 HOXA11 THBS2 FBN1 KCTD16	2.49e-04	494	131	11	JC_fibro_500
CoexpressionAtlas	ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500	PRSS1 KIF26B TMPRSS11E LRP1B TENM2 CRHBP PTH1R PRSS3P2 THBD TENM4 ZFHX4	2.54e-04	495	131	11	PCBC_ratio_DE_vs_SC_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500	SYNPO2 TTC28 KIF26B GRIA1 TENM2 CRHBP THBD NRXN3 TENM4 ZFHX4	2.62e-04	416	131	10	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_100	SYNPO2 DSC3 KIF26B SHOX2 ZFHX4	2.65e-04	92	131	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_100
CoexpressionAtlas	Mesoderm Day 30-reprogram_OSKM - NLT_vs_Mesoderm Day 30-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	NIBAN1 SYNPO2 DSC3 KIF26B BCAT1 RGS9 THBD THBS2 THBS4 FBN1 LRP1	2.81e-04	501	131	11	PCBC_ratio_MESO-30_from-OSKM - NLT_vs_MESO-30_from-ESC_cfr-2X-p05
CoexpressionAtlas	MESO-30 fibroblast_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05	NIBAN1 SYNPO2 DSC3 KIF26B BCAT1 RGS9 THBD THBS2 THBS4 FBN1 LRP1	2.81e-04	501	131	11	PCBC_ratio_MESO-30 fibroblast_vs_MESO-30 blastocyst_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 30-method_plasmid_vs_Mesoderm Day 30-method_NA-Confounder_removed-fold2.0_adjp0.05	NIBAN1 SYNPO2 DSC3 KIF26B BCAT1 RGS9 THBD THBS2 THBS4 FBN1 LRP1	2.81e-04	501	131	11	PCBC_ratio_MESO-30_from-plasmid_vs_MESO-30_from-ESC_cfr-2X-p05
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_500	NIBAN1 SYNPO2 MYO6 KIF26B NAP1L2 BCAT1 CRHBP THBS2 THBS4 ZFHX4	2.83e-04	420	131	10	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_100	DSC3 KIF26B SHOX2 ZFHX4	3.21e-04	53	131	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_100_k1
CoexpressionAtlas	kidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200	TTC28 KIF26B HOXA11 RASEF	3.21e-04	53	131	4	gudmap_kidney_P1_CapMes_Crym_k4_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500	SYNPO2 DSC3 KIF26B NAP1L2 SHOX2 TENM2 TLK1 STXBP3 ZFHX4 RNF180	3.35e-04	429	131	10	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_200	ADAMTS19 GREB1L THBS2 ADAMTS17	4.24e-04	57	131	4	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_200	SYNPO2 DSC3 KIF26B SHOX2 TENM2 ZFHX4	4.34e-04	157	131	6	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#1	DLG5 NAA10 FBN1 ANKRD24	4.84e-04	59	131	4	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500_K1
CoexpressionAtlas	kidney_P0_CapMes_Crym_top-relative-expression-ranked_500	TTC28 KIF26B CHD7 HOXA11 LPIN2 ADAMTS17 RASEF SCARA3	4.88e-04	294	131	8	gudmap_kidney_P0_CapMes_Crym_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000	AKAP6 SYNPO2 KIF26B NAP1L2 GRIA1 BCAT1 TENM2 LRP8 CEP170 NRXN3 ZFHX4 MIGA1 CTNND2 RNF180	5.36e-04	818	131	14	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	PAPPA2 SYNPO2 MYH9 TTC28 KIF26B GRIA1 TENM2 CRHBP THBD NRXN3 TENM4 ZFHX4 MIGA1 ZNF646	5.36e-04	818	131	14	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_200	SYNPO2 KIF26B PROCA1 THBS2 NRXN3 SLC12A1	5.46e-04	164	131	6	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_200	NIBAN1 SYNPO2 NAP1L2 CRHBP THBS4 ZFHX4	5.83e-04	166	131	6	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_200
CoexpressionAtlas	kidney_P1_CapMes_Crym_top-relative-expression-ranked_100	TTC28 KIF26B HOXA11 RASEF	5.85e-04	62	131	4	gudmap_kidney_P1_CapMes_Crym_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_1000	AKAP6 NIBAN1 SYNPO2 DSC3 KIF26B NAP1L2 SHOX2 BCAT1 TENM2 LRP8 CEP170 NRXN3 ZFHX4 RNF180	5.97e-04	827	131	14	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3	DLG5 NIBAN1 SYNPO2 TTC28 KIF26B PPFIBP2 THBS2 FBN1 ZFHX4 ADAMTS17 BOD1L1 ANKRD24 SCARA3 DOP1A	6.48e-04	834	131	14	Facebase_RNAseq_e10.5_Mandibular Arch_2500_K3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_500	KIF26B TENM2 TENM4 ZFHX4	6.60e-04	64	131	4	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000	SYNPO2 DSC3 KIF26B NAP1L2 SHOX2 MARCKSL1 TENM2 LRP8 CEP170 TLK1 STXBP3 ZFHX4 OSBPL1A RNF180	6.63e-04	836	131	14	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PAPPA2 SYNPO2 PTH1R THBS2 FBN1 NRXN3 MEX3A TENM4 C11orf96	4.24e-09	185	131	9	427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn\|World / Primary Cells by Cluster	TTC28 KIF26B LRP8 CEP170 NHSL1 MEX3A TENM4 ZNF608 KCTD16	7.03e-09	196	131	9	9401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B PCLO LRP1B MELTF TENM4 ZFHX4 ROS1 MYO15A	7.57e-08	184	131	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 STRA8 LRP1B PTH1R MALRD1 TENM4 SLC12A1 ADAMTS17	7.57e-08	184	131	8	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B PCLO LRP1B MELTF TENM4 ZFHX4 ROS1 MYO15A	7.57e-08	184	131	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B PCLO LRP1B MELTF TENM4 ZFHX4 ROS1 MYO15A	7.57e-08	184	131	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	P03-Mesenchymal-myocytic_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAPPA2 NIBAN1 SYNPO2 PTH1R THBS2 NRXN3 TENM4 C11orf96	1.28e-07	197	131	8	079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 SYNPO2 PTH1R FBN1 NRXN3 MEX3A TENM4 C11orf96	1.28e-07	197	131	8	9d7a1c7dc70ba5e35645f19f9e056e4fa2494aa0
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 PDE3B COMP TENM2 PTH1R THBS2 TENM4 SCARA3	1.28e-07	197	131	8	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO6 PPFIBP2 SHOX2 RGS3 PTH1R THBS2 ZFHX4 SCARA3	1.33e-07	198	131	8	9d61483b0decac2fe90045b3474843360b2c49b3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	DLG5 ARX CD163 CEP170 NRXN3 MEX3A ZFHX4 C11orf96	1.44e-07	200	131	8	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	KIF26B PCLO TENM2 NHSL1 ZFHX4 OSBPL1A RNF180	1.03e-06	179	131	7	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO6 NAP1L2 LRP1B ZFHX4 OSBPL1A RASEF MYO15A	1.20e-06	183	131	7	262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO6 NAP1L2 LRP1B ZFHX4 OSBPL1A RASEF MYO15A	1.20e-06	183	131	7	c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MARCKSL1 C6orf132 GREB1L FBN1 ZFHX4 ROS1 SCARA3	1.29e-06	185	131	7	a6874dd3030d04380cc3c01de1069461aad4ef45
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 LRP1B PTH1R MALRD1 SLC12A1 KCTD16 ADAMTS17	1.43e-06	188	131	7	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COMP KIF26B THBS2 FBN1 TENM4 ZFHX4 SCARA3	1.65e-06	192	131	7	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTC28 KIF26B THBS2 FBN1 ADAMTS17 LRP1 SCARA3	1.65e-06	192	131	7	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4\|World / Primary Cells by Cluster	ARX CHD7 MARCKSL1 RGS12 NRXN3 ZNF608 RERE	1.71e-06	193	131	7	2eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO6 KIF26B LRP1B ZFHX4 OSBPL1A MYO15A SCARA3	1.71e-06	193	131	7	f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO6 KIF26B LRP1B ZFHX4 OSBPL1A MYO15A SCARA3	1.71e-06	193	131	7	4ccf984baebbb13ae916727137ce593fda7514a2
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PTH1R HOXA11 THBS2 TENM4 ZFHX4 LRP1 SCARA3	1.83e-06	195	131	7	ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE3B BCAT1 CD163 CEP170 PLEKHM2 OSBPL1A LRP1	1.83e-06	195	131	7	9d649ac7d2af313481069c95349efc0c68449e2b
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPPA2 SYNPO2 PTH1R THBS2 C11orf96 KCTD16 ADAMTS17	1.83e-06	195	131	7	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPPA2 SYNPO2 PTH1R THBS2 C11orf96 KCTD16 ADAMTS17	1.83e-06	195	131	7	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	TTC28 LRP8 MEX3A TENM4 ZFHX4 ZNF608 KCTD16	1.89e-06	196	131	7	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	TTC28 LRP8 MEX3A TENM4 ZFHX4 ZNF608 KCTD16	1.89e-06	196	131	7	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal-INs\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ARX CHD7 MARCKSL1 CEP170 NRXN3 MEX3A C11orf96	1.89e-06	196	131	7	556e18eae05bf19259fe02848bcc9120aa2a9d29
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 PTH1R FBN1 NRXN3 MEX3A TENM4 C11orf96	1.96e-06	197	131	7	090a251194da3e2806989d9a522588f83f52da7f
ToppCell	(3)_Chondrocytes-(30)_Chondro\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	PAPPA2 COMP DSC3 CALML3 SHOX2 PTH1R SCARA3	1.96e-06	197	131	7	a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 COMP PPFIBP2 THBS2 THBS4 ZFHX4 LRP1	1.96e-06	197	131	7	cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COMP WNT6 ZKSCAN7 RIMBP3 THBS4 FBN1	2.01e-06	126	131	6	83f3540683b3b175b10af059ab8898c46eaccc13
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COMP WNT6 ZKSCAN7 RIMBP3 THBS4 FBN1	2.01e-06	126	131	6	6d5075d659dac7b96e6857f8485a7d2c4105d685
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COMP WNT6 ZKSCAN7 RIMBP3 THBS4 FBN1	2.01e-06	126	131	6	fd0001a0f3a0a4421f96fd21813c21cf6f01d40e
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COMP WNT6 ZKSCAN7 RIMBP3 THBS4 FBN1	2.01e-06	126	131	6	f20424f9baf3c4059cd6b701761e7595400fc47c
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO6 IRX6 RGS3 PTH1R THBS2 ZFHX4 SCARA3	2.02e-06	198	131	7	6a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 NIBAN1 SYNPO2 THBS2 FBN1 TENM4 C11orf96	2.02e-06	198	131	7	a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO6 RGS3 PTH1R THBS2 TENM4 ZFHX4 SCARA3	2.02e-06	198	131	7	bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	COMP SHOX2 PTH1R THBS2 THBS4 FBN1 ZFHX4	2.09e-06	199	131	7	07b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KIF26B PPFIBP2 ARX CRHBP LRP8 NRXN3 ZNF608	2.16e-06	200	131	7	a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DLG5 DSC3 MYO6 CALML3 PCLO SUN1 C6orf132	2.16e-06	200	131	7	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KIF26B PPFIBP2 ARX CRHBP LRP8 NRXN3 ZNF608	2.16e-06	200	131	7	33b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	HK2 PCLO BCAT1 TENM2 GREB1L NRXN3 RERE	2.16e-06	200	131	7	ac0e023dbb383bbc46c5cc525431778be8f7ef46
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	PCLO GJC2 TENM2 CEP170 NRXN3 ZFHX4 ZNF608	2.16e-06	200	131	7	f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MYO6 RGS3 PTH1R THBS2 TENM4 ZFHX4 SCARA3	2.16e-06	200	131	7	3c898e81444b001835c3f1bbc68183078701b135
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MYO6 RGS3 PTH1R THBS2 TENM4 ZFHX4 SCARA3	2.16e-06	200	131	7	3eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KIF26B PPFIBP2 ARX CRHBP LRP8 NRXN3 ZNF608	2.16e-06	200	131	7	9719fabddc34051949468a7520289e3c750de4f8
ToppCell	Neuronal-Inhibitory-iB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KIF26B ARX CRHBP LRP8 NRXN3 ZNF608 ADAMTS17	2.16e-06	200	131	7	45ddc5ef2caa87ada88327b63ba9b150a6bb3aa5
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COMP CALML3 PROCA1 MELTF THBS2 SCARA3	9.84e-06	166	131	6	37794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COMP CALML3 PROCA1 MELTF THBS2 SCARA3	9.84e-06	166	131	6	81c546c6d847e49e662b81e71992ca0f7a99e890
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 SYNPO2 TENM2 CD163 GREB1L CTNND2	1.13e-05	170	131	6	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 COMP DSC3 THBS2 FBN1 LRP1	1.16e-05	171	131	6	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	Mesenchymal_cells-Osteo-CAR\|Mesenchymal_cells / Lineage and Cell class	COMP PPFIBP2 SHOX2 RGS3 PTH1R ST6GALNAC4	1.29e-05	174	131	6	430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PAPPA2 COMP IRX6 PTH1R THBS2 NIM1K	1.42e-05	177	131	6	915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NIBAN1 RGS9 THBS2 FBN1 ANKRD24 SCARA3	1.42e-05	177	131	6	30f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AKAP6 MELTF MALRD1 SLC12A1 KCTD16 ADAMTS17	1.56e-05	180	131	6	9e09b3dfe344b5d50520711513d389865d73a861
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	KIF26B GREB1L ZFHX4 SYTL3 LPIN2 SCARA3	1.56e-05	180	131	6	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ADAMTS19 SYNPO2 KIF26B NAP1L2 FBN1 ZFHX4	1.61e-05	181	131	6	9b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 NIBAN1 SYNPO2 TENM2 GREB1L CTNND2	1.61e-05	181	131	6	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ABL2 COMP WNT6 THBS2 SYTL3	1.62e-05	107	131	5	7dda60d30c12d9ee15cda5fcbc75c317ca2d026f
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ABL2 COMP WNT6 THBS2 SYTL3	1.62e-05	107	131	5	5356499561a62a80ecd7d9a260aea87bc70543fd
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ABL2 COMP WNT6 THBS2 SYTL3	1.62e-05	107	131	5	8bdfb603ee0e8ca667847be016a9ee5f4f1712f8
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIF26B ARX CRHBP LRP8 ZNF608 PCNT	1.76e-05	184	131	6	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNPO2 HK2 COMP THBS2 C11orf96 LRP1	1.76e-05	184	131	6	c9d7ec17cc5b7ba1b1e721ca392746e8f4a3d41f
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCP2 BCAT1 NRXN3 TENM4 NIM1K ROS1	1.76e-05	184	131	6	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 NIBAN1 SYNPO2 TENM2 GREB1L CTNND2	1.76e-05	184	131	6	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNB HK2 ABL2 BCAT1 CD163 THBD	1.76e-05	184	131	6	e343dd7777a29048e3f12a939f7f782b8b7b4fea
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 NIBAN1 SYNPO2 TENM2 GREB1L CTNND2	1.82e-05	185	131	6	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SYNPO2 MYH9 KIF26B THBS2 C11orf96 SCARA3	1.82e-05	185	131	6	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AKAP6 NIBAN1 SYNPO2 PPFIBP2 TENM2 THBS2	1.88e-05	186	131	6	a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell	Pericytes-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	AKAP6 SYNPO2 PCDHB6 PTH1R GREB1L SCARA3	1.93e-05	187	131	6	35f25780d113f60bf4c13749013c09612ee4ff41
ToppCell	Mesenchymal_cells-Ng2+_MSCs\|Mesenchymal_cells / Lineage and Cell class	PPFIBP2 SHOX2 RGS3 PTH1R CD163 ST6GALNAC4	1.93e-05	187	131	6	e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	AKAP6 NIBAN1 MYH9 RGS3 GREB1L CTNND2	1.99e-05	188	131	6	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABL2 THBS2 FBN1 ZFHX4 LRP1 SCARA3	1.99e-05	188	131	6	c32d023a69b6da79687ff8fa7485e7499db57046
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO6 PPFIBP2 RGS3 PTH1R MELTF ZFHX4	1.99e-05	188	131	6	116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABL2 THBS2 FBN1 ZFHX4 LRP1 SCARA3	1.99e-05	188	131	6	1cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO6 PCDHB5 RGS3 ZFHX4 ADAMTS17 SCARA3	1.99e-05	188	131	6	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	SYNPO2 PTH1R THBS2 FBN1 TENM4 SCARA3	2.05e-05	189	131	6	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD THBS2 FBN1 ZFHX4 LRP1 SCARA3	2.05e-05	189	131	6	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	PRSS1 PRSS2 BCAT1 MARCKSL1 MEX3A ROS1	2.05e-05	189	131	6	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	PPFIBP2 RGS3 PTH1R NHSL1 TENM4 ZFHX4	2.05e-05	189	131	6	46c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPFIBP2 CEP170 PER2 PLEKHM2 AKT2 RERE	2.11e-05	190	131	6	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PPFIBP2 RGS3 PTH1R CD163 ZFHX4 SCARA3	2.11e-05	190	131	6	cf463b2f227f3cc7d3fd296c810c0cbe51cbee72
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 SYNPO2 PTH1R THBS2 KCTD16 ADAMTS17	2.11e-05	190	131	6	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD THBS2 FBN1 ZFHX4 LRP1 SCARA3	2.11e-05	190	131	6	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 SYNPO2 PTH1R THBS2 KCTD16 ADAMTS17	2.11e-05	190	131	6	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD THBS2 FBN1 ZFHX4 LRP1 SCARA3	2.11e-05	190	131	6	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 LRP1B MALRD1 TENM4 SLC12A1 ADAMTS17	2.11e-05	190	131	6	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1B PTH1R MALRD1 TENM4 SLC12A1 ADAMTS17	2.11e-05	190	131	6	cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	AKAP6 NIBAN1 SYNPO2 TENM2 GREB1L CTNND2	2.18e-05	191	131	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron\|World / Primary Cells by Cluster	ARX CHD7 CRHBP NRXN3 ZNF608 C11orf96	2.18e-05	191	131	6	4dd9c8117c4499ed9bde127baf2598603a82080d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1B PTH1R MALRD1 TENM4 SLC12A1 ADAMTS17	2.18e-05	191	131	6	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	AKAP6 NIBAN1 TENM2 RGS3 GREB1L CTNND2	2.18e-05	191	131	6	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	ARX MARCKSL1 NRXN3 MEX3A ZFHX4 C11orf96	2.18e-05	191	131	6	509d17d8ee0d028757ce0f2c9b97e5875f06f0ab
ToppCell	Control-Lymphoid-T_Cytotoxic\|Lymphoid / Disease state, Lineage and Cell class	NIBAN1 MYH9 PDE3B MYO6 SYTL3 ADAMTS17	2.18e-05	191	131	6	ff7204f9b645233548cf804cf6fe0c86417be87f
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO6 PPFIBP2 RGS3 PTH1R ZFHX4 SCARA3	2.18e-05	191	131	6	cc9a6a8fad17d6e1a08a68ab7512ae06b1249051
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PAPPA2 KIF26B LRP1B THBS2 ZFHX4 ADAMTS17	2.18e-05	191	131	6	156b467187331ac6ca390d6ca861d9670bb7b956
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	NIBAN1 SYNPO2 PTH1R THBS2 FBN1 C11orf96	2.18e-05	191	131	6	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO6 PPFIBP2 RGS3 PTH1R ZFHX4 SCARA3	2.18e-05	191	131	6	c16b920ee69ea8536e020ac3475abf1ce972c1e6
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 COMP THBS2 THBS4 FBN1 LRP1	2.18e-05	191	131	6	1b26056df078674f37a6c06f6256b30cfcec21a7
Computational	Metal / Ca ion binding.	COMP CALML3 THBD THBS2 THBS4 FBN1 LRP1	1.05e-04	133	88	7	MODULE_324
Drug	I 333	PRSS1 PRSS2 PTH1R	1.76e-06	5	129	3	CID000533915
Drug	O-4-(ethoxybutyl)berbamine	PRSS1 PRSS2 CALML3	6.12e-06	7	129	3	CID000188375
Drug	AC1L1CUI	PRSS1 FLNB PRSS2 HK2 SLC12A1	6.15e-06	46	129	5	CID000002069
Drug	Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A	DLG5 IQSEC2 RGS12 USP19 PLEKHM2 NFX1 AKT2 SCARA3	1.52e-05	194	129	8	6769_UP
Drug	Dimethadione [695-53-4]; Up 200; 31uM; MCF7; HT_HG-U133A	DSC3 PCLO RGS9 RGS12 THBD MELTF CD101 NFX1	1.64e-05	196	129	8	5668_UP
Drug	Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; HL60; HT_HG-U133A	COMP DSC3 THBD FBN1 LRP1 AKT2 KLK5 DOP1A	1.70e-05	197	129	8	3000_UP
Drug	Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; MCF7; HT_HG-U133A	TTC28 RTEL1 SUN1 N4BP3 RGS12 THBD ZFHX4 RERE	1.70e-05	197	129	8	7412_UP
Drug	AP2PL	PRSS1 PRSS2 HK2 TOP1MT	2.75e-05	31	129	4	CID000121867
Drug	conta-1(35),3,5,7(37),8,10,12,15,32(36),33-decaene-30-carboxylic acid	PRSS1 PRSS2 PDE3B POLR3B ROS1	5.58e-05	72	129	5	CID000489933
Drug	N-allylglycine	PRSS1 PRSS2	9.52e-05	3	129	2	CID000076651
Drug	N-acetyl-L-norvaline methyl ester	PRSS1 PRSS2	9.52e-05	3	129	2	CID000150916
Drug	YAKR-CK	PRSS1 PRSS2	9.52e-05	3	129	2	CID005487256
Drug	2 alpha-bromoacetoxyprogesterone	PRSS1 PRSS2	9.52e-05	3	129	2	CID000135256
Drug	methyl lignocerate	PRSS1 PRSS2	9.52e-05	3	129	2	CID000075546
Drug	GB-107	PRSS1 PRSS2	9.52e-05	3	129	2	CID000056813
Drug	mitorubrinic acid	PRSS1 PRSS2	9.52e-05	3	129	2	CID000379537
Drug	ASA-PE	PRSS1 PRSS2	9.52e-05	3	129	2	CID003037809
Drug	schizopeptin 791	PRSS1 PRSS2	9.52e-05	3	129	2	CID000636821
Drug	Lapg-nh2	PRSS1 PRSS2	9.52e-05	3	129	2	CID003082486
Drug	Methotrexate-polylysine	PRSS1 PRSS2	9.52e-05	3	129	2	CID000163214
Drug	methyl octanesulfonate	PRSS1 PRSS2	9.52e-05	3	129	2	CID000165858
Drug	3HFGB	PRSS1 PRSS2	9.52e-05	3	129	2	CID000126268
Drug	4-chlorobenzenediazonium hexafluorophosphate	PRSS1 PRSS2	9.52e-05	3	129	2	CID002723983
Drug	10-(carboxyethyl)flavin	PRSS1 PRSS2	9.52e-05	3	129	2	CID003082170
Drug	Z-Lys-CH2Cl	PRSS1 PRSS2	9.52e-05	3	129	2	CID000127335
Drug	2,6-dimethyl-3-pyridinol	PRSS1 PRSS2	9.52e-05	3	129	2	CID000070732
Drug	N-phosphopyridoxyl-L-serine	PRSS1 PRSS2	9.52e-05	3	129	2	CID000195946
Drug	Z-Arg-OH	PRSS1 PRSS2	9.52e-05	3	129	2	CID000071055
Drug	p-amidinophenylpyruvate	PRSS1 PRSS2	9.52e-05	3	129	2	CID000444106
Drug	v 1194	PRSS1 PRSS2	9.52e-05	3	129	2	CID000074702
Drug	L-TAPA	PRSS1 PRSS2	9.52e-05	3	129	2	CID000193734
Drug	pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A	DLG5 MYO6 SUN1 NAP1L2 LPIN2 NFX1 LRP1	1.07e-04	190	129	7	7528_DN
Drug	Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A	DLG5 PDE3B WNT6 IQSEC2 SHOX2 ZFHX4 SCARA3	1.14e-04	192	129	7	2831_UP
Drug	Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A	IQSEC2 SUN1 SHOX2 TLK1 ZFHX4 NFX1 RERE	1.18e-04	193	129	7	3378_DN
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A	DLG5 RTEL1 IQSEC2 GSDMB USP19 TLK1 AKT2	1.22e-04	194	129	7	3604_DN
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	PAPPA2 PPFIBP2 SHOX2 N4BP3 RGS12 THBD PER2	1.26e-04	195	129	7	5265_UP
Drug	estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A	RTEL1 CALML3 KIF26B RGS12 GREB1L LPIN2 RPA4	1.26e-04	195	129	7	5205_UP
Drug	Homosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A	AKAP6 WNT6 SHOX2 HOXA11 MELTF TENM4 RERE	1.26e-04	195	129	7	4355_UP
Drug	AG-028671 [847803-03-6]; Up 200; 10uM; PC3; HT_HG-U133A	ABL2 GREB1L THBD PLEKHM2 NFX1 LRP1 COG4	1.26e-04	195	129	7	6557_UP
Drug	Austricine [10180-88-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A	COMP DSC3 RTEL1 SHOX2 THBD FBN1 ST6GALNAC4	1.34e-04	197	129	7	4797_UP
Drug	Melatonin [73-31-4]; Up 200; 17.2uM; HL60; HT_HG-U133A	SHOX2 BCAT1 THBS2 ZFHX4 KLK5 MYO15A ZNF646	1.38e-04	198	129	7	2431_UP
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; MCF7; HT_HG-U133A	PAPPA2 DSC3 CALML3 SUN1 ZFHX4 NFX1 AKT2	1.38e-04	198	129	7	6046_DN
Drug	CP-944629 [668990-94-1]; Up 200; 10uM; MCF7; HT_HG-U133A	TTC28 IQSEC2 SUN1 SHOX2 RGS12 ST6GALNAC4 KLK5	1.38e-04	198	129	7	7497_UP
Drug	SR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A	DLG5 RTEL1 SUN1 PTH1R USP19 PLEKHM2 RERE	1.38e-04	198	129	7	4977_UP
Drug	Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A	PDE3B SUN1 SHOX2 N4BP3 THBD ZFHX4 RERE	1.38e-04	198	129	7	7325_UP
Drug	Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A	PEX6 SHOX2 CD163 THBD NFX1 LRP1 ZNF646	1.43e-04	199	129	7	5686_UP
Drug	Felbinac [5728-52-9]; Up 200; 18.8uM; HL60; HT_HG-U133A	KIF26B SUN1 GRIA1 THBD THBS2 KMT2D KLK5	1.43e-04	199	129	7	3061_UP
Drug	Diethylstilbestrol [56-53-1]; Up 200; 15uM; HL60; HT_HG-U133A	PDE3B ABL2 RTEL1 NAP1L2 HOXA11 TLK1 ST6GALNAC4	1.43e-04	199	129	7	2567_UP
Drug	Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; PC3; HT_HG-U133A	SUN1 RGS9 RGS12 CD163 MELTF LRP1 CTNND2	1.43e-04	199	129	7	7298_UP
Drug	Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A	PAPPA2 PDE3B TTC28 PPFIBP2 GSDMB NFX1 KLK5	1.43e-04	199	129	7	2216_DN
Drug	Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A	AKAP6 PDE3B SHOX2 RGS12 AKT2 RERE MYO15A	1.43e-04	199	129	7	3333_UP
Drug	estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA	ABL2 IQSEC2 SUN1 RGS3 THBD TENM4 NFX1	1.43e-04	199	129	7	1021_UP
Drug	Benzthiazide [91-33-8]; Up 200; 9.2uM; HL60; HT_HG-U133A	AKAP6 PAPPA2 CALML3 KMT2D AKT2 RERE KLK5	1.47e-04	200	129	7	2989_UP
Drug	0ZI	PRSS1 PRSS2 THBD	1.89e-04	20	129	3	CID000122235
Drug	4-Amino-3-nitrobenzoic acid	PRSS1 PRSS2	1.90e-04	4	129	2	CID000074115
Drug	4-ethylpiperidine	PRSS1 PRSS2	1.90e-04	4	129	2	CID000076704
Drug	torquatone	PRSS1 PRSS2	1.90e-04	4	129	2	CID000256516
Drug	mGBSOM	PRSS1 PRSS2	1.90e-04	4	129	2	CID003080804
Drug	Ba-O	PRSS1 PRSS2	1.90e-04	4	129	2	CID000002280
Drug	NSC-13568	PRSS1 PRSS2	1.90e-04	4	129	2	CID000224783
Drug	xylaric acid	PRSS1 PRSS2	1.90e-04	4	129	2	CID003084064
Drug	AC1LAOUV	PRSS1 PRSS2	1.90e-04	4	129	2	CID000492408
Drug	5'-S-propynyl-5'-thioadenosine	PRSS1 PRSS2	1.90e-04	4	129	2	CID000492409
Drug	AC1Q5JO7	PRSS1 PRSS2	1.90e-04	4	129	2	CID000128324
Drug	Dsdgk	PRSS1 PRSS2	1.90e-04	4	129	2	CID000130454
Drug	NSC-45351	PRSS1 PRSS2	1.90e-04	4	129	2	CID000018046
Drug	indomethacin-NHS	PRSS1 PRSS2	1.90e-04	4	129	2	CID000128571
Drug	bromomesaconic acid	PRSS1 PRSS2	1.90e-04	4	129	2	CID006449799
Drug	N-carbobenzoxyglycine vinyl ester	PRSS1 PRSS2	1.90e-04	4	129	2	CID000047309
Disease	Disproportionate short stature	FLNB COMP PTH1R FBN1 PCNT	1.87e-05	77	124	5	C0878659
Disease	Weill-Marchesani syndrome (implicated_via_orthology)	FBN1 ADAMTS17	5.24e-05	3	124	2	DOID:0050475 (implicated_via_orthology)
Disease	osteochondrodysplasia (is_implicated_in)	FLNB COMP PTH1R	6.68e-05	19	124	3	DOID:2256 (is_implicated_in)
Disease	Major Depressive Disorder	PCLO CRHBP LRP8 LRP1 CTNND2 MED12 PCNT	7.83e-05	243	124	7	C1269683
Disease	Weill-Marchesani syndrome	FBN1 ADAMTS17	1.05e-04	4	124	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	FBN1 ADAMTS17	1.05e-04	4	124	2	DOID:0050475 (is_implicated_in)
Disease	Unipolar Depression	PCLO CRHBP LRP8 LRP1 CTNND2 MED12 PCNT	1.16e-04	259	124	7	C0041696
Disease	Malignant neoplasm of breast	AKAP6 ADAMTS19 FLNB MYH9 DSC3 GSDMB KMT2D PER2 UTP20 AKT2 BOD1L1 MED12 DOP1A ZNF646	1.74e-04	1074	124	14	C0006142
Disease	PANCREATITIS, HEREDITARY	PRSS1 PRSS2	1.74e-04	5	124	2	167800
Disease	Malignant Cystosarcoma Phyllodes	KMT2D MED12	1.74e-04	5	124	2	C0600066
Disease	Phyllodes Tumor	KMT2D MED12	1.74e-04	5	124	2	C0010701
Disease	Hereditary pancreatitis	PRSS1 PRSS2	1.74e-04	5	124	2	cv:C0238339
Disease	Autosomal Dominant Hereditary Pancreatitis	PRSS1 PRSS2	1.74e-04	5	124	2	C4080064
Disease	magnesium measurement	ADAMTS19 TTC28 CCDC168 NOM1	1.75e-04	66	124	4	EFO_0004845
Disease	brain measurement, hippocampal volume	MALRD1 UTP20	2.60e-04	6	124	2	EFO_0004464, EFO_0005035
Disease	age at menopause	TTC28 CHD7 HELB TLK1 ZFHX4 BOD1L1 MED12	2.98e-04	302	124	7	EFO_0004704
Disease	central nervous system cancer	PAPPA2 RTEL1 POLR3B	2.99e-04	31	124	3	EFO_0000326
Disease	Mental Retardation, X-Linked 1	IQSEC2 ARX MED12	3.29e-04	32	124	3	C2931498
Disease	sensorineural hearing loss (is_implicated_in)	MYH9 MYO6 MYO15A	3.60e-04	33	124	3	DOID:10003 (is_implicated_in)
Disease	Hereditary pancreatitis	PRSS1 PRSS2	3.63e-04	7	124	2	C0238339
Disease	triacylglycerol 58:6 measurement	LRP1B TENM2	4.82e-04	8	124	2	EFO_0010440
Disease	descending aortic diameter	PAPPA2 FLNB FBN1 LRP1	5.27e-04	88	124	4	EFO_0021788
Disease	Pancreatitis, Chronic	PRSS1 PRSS2	6.19e-04	9	124	2	C0149521
Disease	cerebrospinal fluid biomarker measurement, t-tau measurement	TTC28 AKT2	6.19e-04	9	124	2	EFO_0004760, EFO_0006794
Disease	glioblastoma multiforme	RTEL1 POLR3B	6.19e-04	9	124	2	EFO_0000519
Disease	non-syndromic X-linked intellectual disability (implicated_via_orthology)	IQSEC2 ARX	6.19e-04	9	124	2	DOID:0050776 (implicated_via_orthology)
Disease	asthma exacerbation measurement	PPFIBP2 GSDMB TENM2 MALRD1	6.50e-04	93	124	4	EFO_0007614
Disease	aortic aneurysm	FBN1 LRP1	7.71e-04	10	124	2	EFO_0001666
Disease	gastric adenocarcinoma (is_implicated_in)	RTEL1 KMT2D	9.40e-04	11	124	2	DOID:3717 (is_implicated_in)
Disease	triacylglycerol 58:12 measurement	TRIP12 NRXN3	1.12e-03	12	124	2	EFO_0010439
Disease	Tourette syndrome	TENM2 POLR3B TENM4	1.23e-03	50	124	3	EFO_0004895
Disease	Schizophrenia	GRIA1 RGS9 RGS12 CD163 LRP8 NRXN3 TENM4 LRP1 CTNND2 MED12 PCNT	1.27e-03	883	124	11	C0036341
Disease	phosphatidylcholine 36:5 measurement	ADAMTS19 RASEF	1.54e-03	14	124	2	EFO_0010383
Disease	sleep quality	AKAP6 LRP1B POLR3B TENM4	1.58e-03	118	124	4	EFO_0005272
Disease	diet measurement	KIF26B GRIA1 BCAT1 LRP1B TENM2 RGS3 NRXN3 TENM4 ZNF608 NIM1K RERE CTNND2	1.58e-03	1049	124	12	EFO_0008111
Disease	creatine kinase measurement	AKAP6 CD163 ROS1	1.98e-03	59	124	3	EFO_0004534
Disease	Schizoaffective disorder-bipolar type	PCLO NRXN3	2.02e-03	16	124	2	EFO_0009965
Disease	major depressive disorder (is_implicated_in)	CTNND2 MED12	2.29e-03	17	124	2	DOID:1470 (is_implicated_in)
Disease	irritable bowel syndrome	PCLO LRP8 PER2 RERE	2.31e-03	131	124	4	EFO_0000555
Disease	Idiopathic hypogonadotropic hypogonadism	CHD7 POLR3B	2.56e-03	18	124	2	C0342384
Disease	anorectal malformation	RTEL1 THBS2	2.86e-03	19	124	2	MONDO_0019938
Disease	cataract	TTC28 LRP1B ST6GALNAC4 PCNT	3.01e-03	141	124	4	MONDO_0005129
Disease	Nonorganic psychosis	TENM4 MED12 PCNT	3.10e-03	69	124	3	C0349204
Disease	opioid dependence	MYO6 NHSL1 NRXN3 KCTD16 CTNND2	3.33e-03	237	124	5	EFO_0005611
Disease	neuritic plaque measurement	ELOB TLK1 NRXN3 ZNF608 SYTL3 ADAMTS17	3.64e-03	349	124	6	EFO_0006798
Disease	lung cancer (is_implicated_in)	RTEL1 SHOX2 LRP1B	3.78e-03	74	124	3	DOID:1324 (is_implicated_in)
Disease	Nonsyndromic genetic hearing loss	MYH9 MYO6 MYO15A	4.07e-03	76	124	3	cv:C5680182

Protein segments in the cluster

Peptide	Gene	Start	Entry
ITDFGLCKEGISDGA	AKT2	291	P31751
EAGTSGCGIDAKQVE	CEP170	206	Q5SW79
NGCSAECTGEGGSKE	BCAT1	6	P54687
ASCVEDGFEGDKTGG	ABL2	56	P42684
ESDCTKLFSQGIGGE	COG4	566	Q9H9E3
KDSDGDGIGDACDNC	COMP	396	P49747
DGASSCLGKSLGSED	GSDMB	236	Q8TAX9
SCGEGDISEIESDMG	DOP1A	1336	Q5JWR5
EEGAACGESEVAGAT	ANKRD24	521	Q8TF21
EEEDCTAGEKGISGS	BMS1	526	Q14692
VGSSEEKAADKAEGG	CHD7	2931	Q9P2D1
DGLLCGEANGKDAES	CTNND2	791	Q9UQB3
CDGIIGSAAKEDRCG	ADAMTS17	676	Q8TE56
GSAAKEDRCGVCSGD	ADAMTS17	681	Q8TE56
DAAAGLGDDGKCGEE	NAP1L2	36	Q9ULW6
LGDDGKCGEEAAAGL	NAP1L2	41	Q9ULW6
KCGEEAAAGLGEEGE	NAP1L2	46	Q9ULW6
EVCLTGDSGAGEFKF	PCDHB5	751	Q9Y5E4
EKTEEGSGPCAEAGS	PCP2	6	Q8IVA1
EGDEDAAAALATSCG	RASEF	106	Q8IZ41
EGKGDGCFKDISSIT	C9orf64	221	Q5T6V5
DGLKVCEVADATAGS	RIMBP3B	1131	A6NNM3
DGLKVCEVADATAGS	RIMBP3C	1131	A6NJZ7
SQKAGAEQGCSGDEE	RGS3	866	P49796
CLMDSEDAGTGESGD	RGS9	646	O75916
DCDATCGGGERKTTV	ADAMTS19	926	Q8TE59
ERKAEGGEEDSLGCL	IRX6	221	P78412
GGEEDSLGCLTADTK	IRX6	226	P78412
GLDTEGETCGNAEKL	UROS	111	P10746
GDGLDESDSICGAIT	LRP1B	2746	Q9NZR2
SGGLCDNKDDCGDGS	LRP1B	2906	Q9NZR2
ECGDNSDEDHCGGKL	LRP1B	3741	Q9NZR2
KGDKEGESGTSCNDL	KCTD16	296	Q68DU8
GGNCEIAGKSDADDF	MYO15A	1441	Q9UKN7
EAGAEEACTKAVGAD	GJC2	171	Q5T442
EACTKAVGADGKAAG	GJC2	176	Q5T442
DGSDEAAHCEGKTCG	LRP1	2761	Q07954
GDKDCADGADESIAA	LRP1	2796	Q07954
LGKCEAAGENSDGGD	IQSEC2	681	Q5JU85
AEAGEAAAGKSERDC	KIF26B	906	Q2KJY2
CDVSFLQSEDGSGKG	HK2	886	P52789
TSDCKRVISGGGEGE	CFAP52	426	Q8N1V2
AENSADTGGDGESCL	NHSL1	1301	Q5SYE7
GSSSEACDFLKEDGN	NHSL1	1331	Q5SYE7
EAGEGDVSVGIKCDA	FLNB	771	O75369
GKVGEAGLLSVDCSE	FLNB	1146	O75369
GATETAAVGADCKPG	PER2	1011	O15055
KGGSLGCQTEADSDT	PCLO	3561	Q9Y6V0
DFDLGSGIKLNGDCS	MKNK2	226	Q9HBH9
ESDGTDCCSGKSGEE	PDE3B	591	Q13370
AGGLTEEDEGELCAA	PEX6	656	Q13608
GEACREEKGLAAEDS	NAA10	191	P41227
CGVGEASLDKADSEG	DLG5	926	Q8TDM6
LCGTDVGKSDGFGDF	NFX1	541	Q12986
CGESEAADEKGSIAS	MED12	541	Q93074
CAGDKAGRDSCQGDS	KLK5	231	Q9Y337
EDQSILCTGESGAGK	MYH9	166	P35579
GGGGCRETAAAAEEK	HOXA11	196	P31270
ESGCQTESSKEGEEG	NIM1K	26	Q8IY84
EEKDCGGGDALSNGI	OSBPL1A	516	Q9BXW6
AGAGETLKQECDSLG	GREB1L	1176	Q9C091
VTKEDSALCGGGDIC	PCNT	56	O95613
AGTKTGADLSDGTCE	PPFIBP2	21	Q8ND30
GAEDGSVDTCKGDSG	PRSS41	236	Q7RTY9
IGACSDEGTAQEGKA	MARCKSL1	131	P49006
AKGAEASAASEEEAG	MARCKSL1	156	P49006
GGGAAIDDIEFKNCT	MALRD1	1661	Q5VYJ5
GDGKVSERLGEECDD	PAPPA2	1116	Q9BXP8
GDGCSKVCELEEGFN	PAPPA2	1136	Q9BXP8
DDAVTSAGSEEKCDG	BOD1L1	1651	Q8NFC6
EGGRICENGADDDKL	C6orf132	596	Q5T0Z8
EGETLAFLCKAGGAE	CD101	426	Q93033
AGSVGCCSEKQEEDG	DSC3	861	Q14574
KKSSAGCEGIGDFVE	CRHBP	231	P24387
LDDGKTLGECGFTSQ	ELOB	51	Q15370
GDGIKCTDLDECSNG	FBN1	1356	P35555
DAEGKDGEDSVCLSA	ARX	301	Q96QS3
DKDGDGCITTRELGT	CALML3	21	P27482
SEAGEKADGVASKGD	CCDC168	4126	Q8NDH2
ECGSGGGDSKDKTSA	GRIA1	786	P42261
AEDAGVICSKGADLS	CD163	251	Q86VB7
AGGDGDALCVTEEDL	SCARA3	6	Q6AZY7
DVSTFSEGGDCKEPD	PROCA1	51	Q8NCQ7
FIDAEELCSGGVKAG	HELB	41	Q8NG08
IDDSLDQDEVGGGSC	CNST	651	Q6PJW8
EKDCEGGADEAGCAT	LRP8	151	Q14114
GCDKEALLTGGGSEN	RNF180	146	Q86T96
DVEATDGGGLSGKCS	PCDHB6	316	Q9Y5E3
CLSSAEDSGVDEGQG	PLEKHM2	561	Q8IWE5
EDEACGSIKLGAGDA	MIGA1	236	Q8NAN2
AVCRGKASEGLDFSD	RTEL1	621	Q9NZ71
GDTAVGGDACSLSKL	SYTL3	576	Q4VX76
GVACADEKAESDGEE	UTP20	2591	O75691
CSAKGGRGDVGSADI	SRPRB	246	Q9Y5M8
VGFLEGGKDSCQGDS	PRSS3P2	186	Q8NHM4
IGTDCDSGKVDGGDS	THBD	476	P07204
GDSSGEGVCDKSPLE	MELTF	191	P08582
TEEKDGGLGNEETLC	SLC16A14	246	Q7RTX9
DGLKVCEVADATAGS	RIMBP3	1131	Q9UFD9
LSDQGSDGCDDDGLV	NRXN3	386	Q9HDB5
GAKEPTGCTEAGRDD	SHOX2	36	O60902
KDNECEEESGGIRGL	SLC12A1	846	Q13621
EARCGDGGKAIDATL	TENM2	1341	Q9NT68
SEDGDITDKSLCGSG	NOM1	321	Q5C9Z4
GGSTEDGCVAASRDD	RERE	346	Q9P2R6
DTVSDVGVGLCDEKG	SANBR	501	Q6NSI8
CKTEQDLALGTDAEG	STXBP3	366	O00186
EPACAEGSVKDSGVD	STRA8	216	Q7Z7C7
VDDKGGCEEDNASAV	AKAP6	301	Q13023
RDCGSDAAEDSASKG	C11orf96	76	Q7Z7L8
SDLTKFGDCGGSDDE	DNTTIP2	386	Q5QJE6
SLEGKTDACQGDSGG	TMPRSS11E	361	Q9UL52
RDKDGDGVGDACDSC	THBS4	591	P35443
DGTACGEIKITDFGL	TLK1	596	Q9UKI8
LGSGLGAEIDSAECV	ST6GALNAC4	86	Q9H4F1
KSGEGENTDKLECGT	ZFHX4	1891	Q86UP3
ASKELECAEDPGSAG	USP19	1036	O94966
EGTDLEGDMLDCSGS	nan	46	Q6ZSR9
DGASGGSDQLCERDA	RPA4	16	Q13156
SDGELTGADLKDCVS	RGS12	671	O14924
KASGSGLCEGDEVVS	SYNPO2	41	Q9UMS6
EGDKEDTCEVAFLGA	SYNPO2	426	Q9UMS6
EGRGGKCTEEGDASQ	NIBAN1	826	Q9BZQ8
GADKKAEAGAGSATE	RPS10P5	146	Q9NQ39
DGFLNGSCSGLDEEA	PTH1R	561	Q03431
CFGGSAKDRGLLEDE	MEX3A	21	A1L020
DLCDGQLEGAEIGST	RTCA	61	O00442
GGDSGNVDDDCERVK	USP47	846	Q96K76
DGDCLQAESEGDKCG	ZNF646	726	O15015
GNEKEDGEAADTVGC	TOP1MT	326	Q969P6
GCGDDVDFGDEKSRL	WNT6	171	Q9Y6F9
TACGDSKDNDGDGLV	TENM4	836	Q6N022
FDDTRCGDGGKATEA	TENM4	1331	Q6N022
VLATECGQGEEKSEG	ROS1	2276	P08922
GTAFGGSKVKDVCED	POLR3B	961	Q9NW08
VGFLEGGKDSCQGDS	PRSS2	186	P07478
KDRALESDAACGLGG	TTC28	991	Q96AY4
AATAGAGSCGKSKEE	ZNF608	176	Q9ULD9
ENEACAVLGGSDSEK	UBR7	31	Q8N806
PGAAETGDVCEDTFK	ZKSCAN7	306	Q9P0L1
TACTLGDGEAVGADS	SUN1	61	O94901
VGFLEGGKDSCQGDS	PRSS1	186	P07477
SGQEDFDKDGIGDAC	THBS2	726	P35442
CVKSGSGSESTGAEE	TRIP12	156	Q14669
LLCDAGTAISGGKAE	KMT2D	1271	O14686
CDVGVSSDDDKGAQA	LPIN2	181	Q92539
DFEEAGSTSGGCNLK	MYO6	351	Q9UM54
CEELKRGLGDEDGSN	N4BP3	266	O15049