Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainCalpain_III

CAPN9 CAPN8

3.69e-0412452IPR022683
Domaincalpain_III

CAPN9 CAPN8

3.69e-0412452SM00720
DomainC2_III

CAPN9 CAPN8

3.69e-0412452IPR033883
DomainCalpain_domain_III

CAPN9 CAPN8

4.35e-0413452IPR022682
Domain-

PLA2R1 MMP9

4.35e-04134522.10.10.10
DomainCalpain_III

CAPN9 CAPN8

4.35e-0413452PF01067
DomainFN_type2_col-bd

PLA2R1 MMP9

5.07e-0414452IPR000562
DomainFN2_2

PLA2R1 MMP9

5.07e-0414452PS51092
DomainCalpain_cysteine_protease

CAPN9 CAPN8

5.07e-0414452IPR022684
Domainfn2

PLA2R1 MMP9

5.07e-0414452PF00040
DomainFN2_1

PLA2R1 MMP9

5.07e-0414452PS00023
DomainFN2

PLA2R1 MMP9

5.07e-0414452SM00059
DomainCysPc

CAPN9 CAPN8

5.84e-0415452SM00230
DomainPeptidase_C2_calpain_cat

CAPN9 CAPN8

5.84e-0415452IPR001300
DomainPeptidase_C2

CAPN9 CAPN8

5.84e-0415452PF00648
DomainCALPAIN_CAT

CAPN9 CAPN8

5.84e-0415452PS50203
DomainTPR_REGION

TTC27 TTC39B TRANK1 TTC38

6.60e-04165454PS50293
DomainTPR

TTC27 TTC39B TRANK1 TTC38

6.60e-04165454PS50005
DomainSRCR

TMPRSS2 LOXL2

1.16e-0321452PF00530
Domain-

TTC27 TTC39B TRANK1 TTC38

1.53e-032074541.25.40.10
DomainSR

TMPRSS2 LOXL2

1.64e-0325452SM00202
Domain-

TMPRSS2 LOXL2

1.64e-03254523.10.250.10
DomainSRCR_1

TMPRSS2 LOXL2

1.78e-0326452PS00420
DomainSRCR_2

TMPRSS2 LOXL2

1.78e-0326452PS50287
DomainSRCR-like_dom

TMPRSS2 LOXL2

1.78e-0326452IPR017448
DomainTHIOL_PROTEASE_CYS

CAPN9 CAPN8

1.78e-0326452PS00139
DomainHECT

HERC1 HECW2

1.92e-0327452PF00632
DomainHECTc

HERC1 HECW2

1.92e-0327452SM00119
DomainTHIOL_PROTEASE_ASN

CAPN9 CAPN8

1.92e-0327452PS00640
DomainHECT_dom

HERC1 HECW2

1.92e-0327452IPR000569
DomainTHIOL_PROTEASE_HIS

CAPN9 CAPN8

1.92e-0327452PS00639
DomainSRCR

TMPRSS2 LOXL2

1.92e-0327452IPR001190
DomainHECT

HERC1 HECW2

1.92e-0327452PS50237
DomainPept_cys_AS

CAPN9 CAPN8

2.06e-0328452IPR000169
DomainTPR-like_helical_dom

TTC27 TTC39B TRANK1 TTC38

2.36e-03233454IPR011990
DomainKringle-like

PLA2R1 MMP9

2.69e-0332452IPR013806
DomainTPR

TTC27 TTC39B TRANK1

3.70e-03129453SM00028
DomainTPR_repeat

TTC27 TTC39B TRANK1

4.03e-03133453IPR019734
Pubmed

Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense.

CAPN9 CAPN8

1.79e-06247220686710
Pubmed

A Gastrointestinal Calpain Complex, G-calpain, Is a Heterodimer of CAPN8 and CAPN9 Calpain Isoforms, Which Play Catalytic and Regulatory Roles, Respectively.

CAPN9 CAPN8

1.79e-06247227881674
Pubmed

Cancer-educated neutrophils promote lung cancer progression via PARP-1-ALOX5-mediated MMP-9 expression.

MMP9 ALOX5

5.36e-06347238172525
Pubmed

The calpain family and human disease.

CAPN9 CAPN8

1.07e-05447211516996
Pubmed

Identification of TMPRSS2-ERG mechanisms in prostate cancer invasiveness: Involvement of MMP-9 and plexin B1.

TMPRSS2 MMP9

1.07e-05447228004109
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KDM3B IFT80 TRANK1 EMC1 HECW2 CHD5

7.62e-0552947614621295
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KDM3B ARFGEF2 ULK4 HERC1 NUP85 TTC38 ALOX5 CHD5

1.06e-04110547835748872
Pubmed

Phenotypic analysis of mice lacking the Tmprss2-encoded protease.

TMPRSS2 MMP9

1.17e-041247216428450
Pubmed

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

TTC27 IFT80 EMC1 NUP85

1.85e-0420947426389662
Pubmed

Voxelwise genome-wide association study (vGWAS).

EMC1 AKR7L

1.86e-041547220171287
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

PLA2R1 DCHS2

2.40e-041747220639394
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

HERC1 HECW2

5.69e-042647226949039
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

KDM3B ULK4 PLA2R1 TRANK1 EHF

8.76e-0455247510737800
Pubmed

Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development.

MMP9 PDK1

9.75e-043447234767447
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ARFGEF2 PLA2R1 CLSTN3 ST3GAL2 EMC1 LOXL2 DGAT1

1.08e-03120147735696571
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

IFT80 HECW2 CHD5

1.17e-0315347310718198
Pubmed

A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis.

SLC4A8 MMP9

1.22e-033847238346162
Pubmed

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

IFT80 HERC1

1.35e-034047229078390
Cytoband1p36.13

EMC1 AKR7L

1.53e-03564721p36.13
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC27 TTC39B TRANK1 TTC38

5.51e-05115334769
GeneFamilyC2 domain containing|Calpains

CAPN9 CAPN8

3.34e-0415332975
GeneFamilyCadherin related

DCHS2 CLSTN3

4.32e-041733224
CoexpressionGSE7852_TREG_VS_TCONV_LN_UP

ST3GAL2 IFT80 FNTA GPR68 DGAT1 RNF135

1.52e-06200476M5727
CoexpressionGSE7460_TCONV_VS_TREG_LN_DN

ST3GAL2 IFT80 FNTA GPR68 DGAT1 RNF135

1.52e-06200476M5674
CoexpressionGRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP

TTC27 TTC39B OAS3 PLA2R1 CLSTN3 ST3GAL2 HERC1 RTP4 DGAT1 RNF135

3.01e-0511514710M1103
CoexpressionGRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP

TTC27 TTC39B OAS3 PLA2R1 CLSTN3 ST3GAL2 HERC1 RTP4 DGAT1 RNF135

5.14e-0512264710MM979
ToppCelldroplet-Marrow-BM-1m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 RTP4 ALOX5 DGAT1

8.71e-07166475758817f38e843db4ef6ab3e2bfb9f1a2075c9af9
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

CAPN9 CAPN8 PLA2R1 TMEM45A EHF

1.45e-06184475d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellLPS_anti-TNF-Epithelial_alveolar|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TMPRSS2 RTKN2 ATP11A VARS2 EHF

2.07e-0619847553e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TMPRSS2 RTKN2 ATP11A VARS2 EHF

2.07e-06198475f006d68e6c51923be7772eea118546a5762e8a5e
ToppCellLPS_IL1RA-Epithelial_alveolar|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TMPRSS2 RTKN2 ATP11A VARS2 EHF

2.12e-061994755b140ac88ebc25ce397ae577e48f3e271faf46e7
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPN9 CAPN8 TMPRSS2 RTKN2 ATP11A

2.12e-06199475f8846446ebbc4948cdc69640782db1358bbdc486
ToppCellBiopsy_IPF-Epithelial-Transitional_AT2|Biopsy_IPF / Sample group, Lineage and Cell type

CAPN8 TMPRSS2 RTKN2 ATP11A C1orf167

2.12e-0619947583ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCellParenchyma_COVID-19-Epithelial-TX-AT1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

CAPN9 CAPN8 TMPRSS2 RTKN2 ATP11A

2.12e-06199475fe9f5bc317be0c35bd96311bf0b3c7b91d98acc5
ToppCellASK428-Epithelial|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CAPN8 TMPRSS2 RTKN2 ATP11A EHF

2.12e-06199475ba2aaaeb4d9b448a6b9660b152fcac1a0e3fcfe7
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CAPN9 CAPN8 TMPRSS2 RTKN2 ATP11A

2.12e-061994753e35ee426ef06f9af568c37349b62dd1ee9b97ea
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TMPRSS2 RTKN2 ATP11A VARS2 EHF

2.18e-06200475c89f3cb36bb14c476d6a392bfd3ded1c8feecfeb
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

OAS3 CLSTN3 TRANK1 TTC38 TBX21

2.18e-062004752281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMPRSS2 TBX21 EHF ZDHHC16

6.87e-06116474a07f16917c66ce25f23ebef350d693cc4c324075
ToppCellfacs-Skin-nan-18m-Myeloid-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 RTP4 ALOX5

1.84e-0514947423a1b95c12f2e3708dc003e13fab423e89821f11
ToppCellfacs-Skin-nan-18m-Myeloid-macrophage|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 RTP4 ALOX5

1.84e-05149474c53a3226adc8fd0eaaa842b6a96442287580cbe0
ToppCellfacs-Skin-nan-18m-Myeloid|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 RTP4 ALOX5

1.84e-05149474bb18a18b891af85849b9658d774053f839c9a8e1
ToppCellfacs-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 NHSL2 ALOX5

2.21e-05156474034d4359359a44c205c6931f38a375271ac2752b
ToppCellfacs-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 NHSL2 ALOX5

2.21e-051564742a4dac4100c0339aad4905b8eaca6e8fe806718b
ToppCellfacs-Spleen-nan-24m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 NHSL2 ALOX5

2.21e-0515647421267718d3a3dc19988663b6846aed8bb3eae836
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AK9 SLC4A8 TMEM45A TBX21

2.21e-05156474a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCelldroplet-Lung-LUNG-1m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 RTP4 DGAT1

2.32e-0515847430cceb73cf5e24b692da84d33342fd3b1ad5efe5
ToppCellfacs-Heart-RV-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 ALOX5 DGAT1

2.32e-051584742a222301474c4dfd9a776e197c10f4c1cacceb62
ToppCellfacs-Heart-RV-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 ALOX5 DGAT1

2.32e-05158474ff9878fd768f22bf2ee4805bac2ba01cb3cb804a
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 RTP4 DGAT1

2.32e-0515847447793463640f98ee5f680a1ee5786b453355fd57
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

CAPN9 CAPN8 TMPRSS2 ATP11A

2.62e-05163474e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCelldroplet-Spleen-nan-18m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTKN2 MMP9 NHSL2 ALOX5

2.62e-05163474bc37c5d9f48b16096d5313657563f3ec84028c8c
ToppCelldroplet-Spleen-nan-24m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

2.75e-051654743cdb921f5b9facf04f81995d5641ac14ef3dbb6f
ToppCelldroplet-Spleen-nan-21m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

2.88e-05167474cfcd72292c733cdb18c92fdb61b68f6806d22c8c
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

2.95e-051684743611605114f6b668b44728d6563cd02389e106af
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

2.95e-05168474c0ff30e2c47005514131a0866cf10a1c228128fc
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 ALOX5 DGAT1

3.02e-05169474a5964aef04093b460bbe29d5e2e7389f8fd2d46f
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.02e-05169474f38b52972a6c492ce2fd520a26bb3fc8db23bf85
ToppCellfacs-Marrow-Granulocytes-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.02e-05169474ee1969755180df58d32904e2bb4192da9373d03e
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.02e-051694745320da1d61806b53e0bd96bbdfdb8fd69246681b
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 ALOX5 DGAT1

3.02e-05169474e0076aa61b4ef3f836f5750005d0469d3982eb6d
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-7|TCGA-Lung / Sample_Type by Project: Shred V9

CAPN8 TMPRSS2 ATP11A ZDHHC16

3.02e-051694745f522a10b6ec24a353f53bec2f779a81cd5f9581
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 ALOX5 DGAT1

3.02e-051694742341eddfedaad8cee779c37bb87f7def058588ca
ToppCellfacs-Marrow-Granulocytes-18m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 ALOX5 DGAT1

3.02e-0516947494871936ccfc73b56d425373b989b87c059d4493
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.02e-051694741000eaf5158596b4898bedcc802b31db76b05a48
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.02e-0516947483b854fa8fd9017df8f9207d9ced260eee98e8c1
ToppCellfacs-BAT-Fat-3m-Myeloid-granulocyte|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 ALOX5 DGAT1

3.09e-051704748fd0a55266066a51266ab616c38c883e2680bcf4
ToppCelldroplet-Spleen-nan-3m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.09e-05170474dbd6c9c7be824a1ff1b31af791064127cafbd194
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.16e-05171474ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCellfacs-Marrow-Granulocytes|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.16e-051714741701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.16e-0517147497ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCelldroplet-Marrow-BM-1m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 MMP9 ALOX5 DGAT1

3.16e-051714748a0c08f0aa3a80cd6346c81deb242e430ebd897b
ToppCelldroplet-Marrow-nan-3m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 RTP4 ALOX5 DGAT1

3.24e-05172474cfcfa7eeff1805bedf10a3c07826459914c3e872
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HERC1 NHSL2 ALOX5 DGAT1

3.24e-05172474c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 TRANK1 MMP9 NHSL2

3.24e-05172474d354424c1f861b6607dfd63b9724f4c237b30275
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HERC1 NHSL2 ALOX5 DGAT1

3.24e-05172474953b05f776348cff784e79c93df65841939d880f
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAPN8 DCHS2 TMEM45A EHF

3.31e-05173474464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 NUP85 GPR68 EHF

3.39e-051744747be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC4A8 NUP85 GPR68 EHF

3.46e-051754741b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.62e-05177474065bebd22031f143e90a407f952b444a3f8818c7
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OAS3 TRANK1 TTC38 TBX21

3.62e-05177474d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OAS3 TRANK1 TTC38 TBX21

3.62e-05177474f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

OAS3 TRANK1 TTC38 TBX21

3.62e-051774746978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

OAS3 TRANK1 TTC38 TBX21

3.62e-05177474936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

OAS3 TRANK1 TTC38 TBX21

3.62e-05177474d5aeda113afaa2425874394610344570c9078478
ToppCellfacs-Marrow-Granulocytes-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NHSL2 ALOX5 DGAT1

3.62e-05177474eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CAPN9 CAPN8 ARSH EHF

3.95e-05181474bab282cb0d9fc049f6fb094cf8b1fba104f4ea17
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

CAPN8 TMPRSS2 TMEM45A EHF

3.95e-05181474c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

CAPN8 TMPRSS2 ATP11A EHF

4.21e-05184474369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellRSV-Healthy-5|Healthy / Virus stimulation, Condition and Cluster

OAS3 RTKN2 MMP9 HECW2

4.21e-051844741e282d619ef8035437fabe0fd2aefda1c142f7f6
ToppCellRSV-Healthy-5|RSV / Virus stimulation, Condition and Cluster

OAS3 RTKN2 MMP9 HECW2

4.21e-05184474ba958f731de6c9eff60103d483e020e2c0c7af7c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

CAPN9 CAPN8 TMPRSS2 EHF

4.30e-05185474673f0c688ae6984bc8027df2da335787924f4137
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

CAPN8 TMPRSS2 TMEM45A EHF

4.30e-05185474cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCOVID-19_Moderate-NK_activated|World / disease group, cell group and cell class

OAS3 TRANK1 TTC38 TBX21

4.39e-05186474ff8f32f69516bf785224fa12f8139a95359b0279
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMPRSS2 ATP11A VARS2 EHF

4.39e-05186474e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CAPN8 TMPRSS2 ATP11A EHF

4.39e-051864742ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMPRSS2 RTKN2 ATP11A IFT80

4.39e-051864744e94158db52df41d71e67b02b9895a358eebee0f
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ST3GAL2 IFT80 TMEM45A GPR68

4.48e-051874744527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CAPN8 TMPRSS2 ATP11A EHF

4.48e-051874745df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TTC39B OAS3 TRANK1 RTP4

4.58e-051884746f8946d4710f6e32c937213f99b790b098b8819c
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

CAPN8 TMPRSS2 RTKN2 ATP11A

4.58e-05188474707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CAPN8 TMPRSS2 ATP11A CLSTN3

4.67e-051894742d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

CAPN8 TMPRSS2 TMEM45A EHF

4.67e-05189474f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CAPN8 TMPRSS2 ATP11A EHF

4.77e-0519047427a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellPND07-Epithelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMPRSS2 RTKN2 ATP11A EHF

4.77e-05190474e3a2c8b637f60c963520dffe99c526809d818cab
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

CAPN8 TMPRSS2 TMEM45A EHF

4.87e-05191474c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAPN8 TMPRSS2 ATP11A EHF

4.87e-05191474a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

CAPN8 TMPRSS2 TMEM45A EHF

4.87e-051914743c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

CAPN8 TMPRSS2 ATP11A EHF

4.87e-05191474276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell(7)_Epithelial-E_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CAPN8 TMPRSS2 ATP11A C1orf167

4.87e-051914740fc8d109d5c50957ceef5b8b8b818b0c598b1bbe
ToppCellBLOOD--(1)_gd_T_cells| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CLSTN3 TTC38 GPR68 TBX21

4.87e-0519147447ced00ed6fb47ddc6e9baa76186ea974720defd
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAPN8 TMPRSS2 ATP11A EHF

4.87e-05191474e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TMPRSS2 RTKN2 SLC4A8 EHF

4.97e-0519247425378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

CAPN8 TMPRSS2 ATP11A EHF

4.97e-05192474499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

CAPN8 TMPRSS2 ATP11A EHF

4.97e-0519247458c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

CAPN8 TMPRSS2 ATP11A EHF

4.97e-05192474efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell(7)_Epithelial-C_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CAPN8 TMPRSS2 ATP11A EHF

5.07e-05193474a3ca6ab20c8de260e410ddc14d3d202f28b9d6c2
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC39B RTKN2 HERC1 PDK1

5.07e-051934749337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

CAPN8 TMPRSS2 ATP11A EHF

5.07e-05193474738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

CLSTN3 TRANK1 HERC1 CHD5

5.17e-051944748aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CAPN8 TMPRSS2 RTKN2 ATP11A

5.17e-0519447453f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell(7)_Epithelial_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CAPN8 TMPRSS2 ATP11A EHF

5.17e-05194474413e8b9f1e15be363a7f4a8f727af3eeb9e9a928
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

OAS3 TRANK1 NHSL2 TBX21

5.27e-05195474662b50a2aa97373bf343b88caace9717049c722a
ToppCell390C-Epithelial_cells-Epithelial-C_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

CAPN8 TMPRSS2 ATP11A EHF

5.27e-05195474d0608db4a61576e67f4a3a52e1f84d788a1dea85
ToppCell390C-Epithelial_cells-Epithelial-C_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

CAPN8 TMPRSS2 ATP11A EHF

5.27e-05195474bdfe486d32cb598950c1a5f5cdab40302c8f0f99
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

TTC39B OAS3 TRANK1 RTP4

5.27e-05195474b64d9e1a8834401b4dc501566546647754ae21fc
DiseaseMultiple Organ Failure

MMP9 ALOX5

6.33e-058452C0026766
Diseaseabdominal aortic aneurysm (implicated_via_orthology)

MMP9 EHF

8.13e-059452DOID:7693 (implicated_via_orthology)
DiseaseAsthma

MMP9 ALOX5 TBX21

2.51e-0480453C0004096
DiseaseX-11470 measurement

TTC27 VARS2

3.83e-0419452EFO_0021241
Diseaseserum gamma-glutamyl transferase measurement

TMPRSS2 FAM227A IFT80 TRANK1 SLC4A8 EHF RNF135

4.34e-04914457EFO_0004532
Diseasepulmonary hypertension (is_implicated_in)

MMP9 ALOX5

9.63e-0430452DOID:6432 (is_implicated_in)
Diseasearteriosclerosis (is_implicated_in)

MMP9 ALOX5

1.03e-0331452DOID:2349 (is_implicated_in)
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

TTC27 TTC39B SLC4A8 MMP9

1.17e-03303454EFO_0004612, EFO_0020945
DiseaseMiddle Cerebral Artery Embolus

MMP9 ALOX5

1.24e-0334452C0751845
DiseaseEmbolic Infarction, Middle Cerebral Artery

MMP9 ALOX5

1.24e-0334452C0751847
DiseaseLeft Middle Cerebral Artery Infarction

MMP9 ALOX5

1.24e-0334452C0751846
DiseaseRight Middle Cerebral Artery Infarction

MMP9 ALOX5

1.24e-0334452C0751849
DiseaseThrombotic Infarction, Middle Cerebral Artery

MMP9 ALOX5

1.24e-0334452C0751848
DiseaseMiddle Cerebral Artery Occlusion

MMP9 ALOX5

1.24e-0334452C0740391
DiseaseInfarction, Middle Cerebral Artery

MMP9 ALOX5

1.24e-0334452C0740392
DiseaseMiddle Cerebral Artery Thrombosis

MMP9 ALOX5

1.24e-0334452C0740376
DiseaseMiddle Cerebral Artery Syndrome

MMP9 ALOX5

1.24e-0334452C0238281
Diseasebrain ischemia (implicated_via_orthology)

MMP9 ALOX5

1.31e-0335452DOID:2316 (implicated_via_orthology)
Diseasesexual dimorphism measurement

TTC39B ULK4 TRANK1 HERC1 MMP9 LOXL2 RNF135

1.33e-031106457EFO_0021796
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CAPN9 CAPN8

1.39e-0336452DOID:11723 (implicated_via_orthology)
Diseasehereditary spastic paraplegia (implicated_via_orthology)

CAPN9 CAPN8

1.97e-0343452DOID:2476 (implicated_via_orthology)
Diseasehomocysteine measurement

DCHS2 C1orf167

2.26e-0346452EFO_0004578
Diseaseglucose measurement

IFT80 HERC1 TMEM45A DGAT1

2.66e-03380454EFO_0004468
DiseaseNeoplasm Invasiveness

MMP9 ALOX5 LOXL2

2.79e-03184453C0027626
DiseaseInfluenza

OAS3 RTP4

2.87e-0352452C0021400

Protein segments in the cluster

PeptideGeneStartEntry
KDNLNQLYQHHWTEW

FAM227A

481

F5H4B4
QLYQHHWTEWNYFDK

FAM227A

486

F5H4B4
HWHSCWQGQQFLHEK

C1orf167

971

Q5SNV9
WHQKDCATVWKAHYV

ARSH

436

Q5FYA8
TQWAEIYRNHFWKEH

AKR7L

226

Q8NHP1
LWKLEQVCDDEWHHY

CLSTN3

436

Q9BQT9
WHCSWVKELQLELYH

CHD5

521

Q8TDI0
SYGHTFEKHWWQDLF

ARFGEF2

1361

Q9Y6D5
EEVHKWNLVLFNGHW

CAPN8

351

A6NHC0
NWNIPVHKWCIRHFY

DGAT1

376

O75907
AAWKHYNTNHEADDW

PDK1

406

Q15118
YHDNHIVIRWFWAAV

HECW2

1471

Q9P2P5
WHHHNITYWIQNYSE

MMP9

116

P14780
EVDEQHQLVQWFWHT

HERC1

4746

Q15751
HQLVQWFWHTLEEFS

HERC1

4751

Q15751
ETWYWHGDVNSNKVV

LOXL2

491

Q9Y4K0
LKWQHWHEECERYLQ

NUP85

256

Q9BW27
FVEFDGCNWKQHSWV

KDM3B

66

Q7LBC6
HDGKDNYHWNYLLSW

DCHS2

3226

Q6V1P9
SADRWNYWHFEQHVK

FADS2B

246

A8MWK0
AHVVEQHWEWKNFQV

IFT80

296

Q9P2H3
QWHEIHPQYWTKYQV

EHF

41

Q9NZC4
QGKSWHYQLWDYDQV

C19orf54

291

Q5BKX5
HSENWVVYQYWNTKA

EMC1

786

Q8N766
FHFQFWQHSEWLDVV

CAPN9

131

O14815
VKHWYHQVCLQGLWK

OAS3

206

Q9Y6K5
FWLQYVLQHDNWSHG

GPR68

76

Q15743
EAFWQHFFDLSQWKH

RTKN2

386

Q8IZC4
CHTYWEHWTSQGQVR

RTP4

71

Q96DX8
FHQKNWQHWFSHIGD

VARS2

506

Q5ST30
QHQNWYVIDGFHSKW

AK9

1576

Q5TCS8
GKHYWEVDTRNCSHW

RNF135

311

Q8IUD6
HAAVNFGQYDWCSWI

ALOX5

551

P09917
HHWYLTDWKSGDTYQ

NHSL2

636

Q5HYW2
DAKNYHAWQHRQWVI

FNTA

196

P49354
NWHHYWENNRYAGEF

ST3GAL2

306

Q16842
YWKDHNIVTAEVHWA

SLC4A8

651

Q2Y0W8
WKNWTHAQHFCAEEG

PLA2R1

981

Q13018
ALDTHYWTWINHFVI

ATP11A

1021

P98196
LQHYCQAWEIKHWRK

C17orf64

96

Q86WR6
TAEKQNWLHSYFHKW

TDP1

466

Q9NUW8
TYNHEKAHSYWNWIQ

SUN5

216

Q8TC36
KSWHPVCQDDWNENY

TMPRSS2

166

O15393
SVQEEWKQFHHLCYW

TTC39B

421

Q5VTQ0
CWHFFYSHWNLILIV

ZDHHC16

116

Q969W1
ACHNYWHWALYLIEK

TTC38

251

Q5R3I4
EWIAQGDYYAKHQCW

TRANK1

1701

O15050
ALKCNYEHWQIWENY

TTC27

621

Q6P3X3
DYKQGHWNQLLGWHH

TMEM45A

81

Q9NWC5
LVDQHHWRYQSGKWV

TBX21

191

Q9UL17
FHEWYETSNHLWLVV

ULK4

61

Q96C45