Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

1.35e-051901148GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

2.50e-052071148GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

2.97e-052121148GO:0017171
GeneOntologyMolecularFunctionendopeptidase activity

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 ADGRG6 CFD PAPPA SPPL2C

3.58e-0543011411GO:0004175
GeneOntologyMolecularFunctioninterleukin-12 receptor binding

JAK2 IL23R

3.19e-0451142GO:0005143
GeneOntologyMolecularFunctionpeptidase activity

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 ADGRG6 CFD TGM2 PAPPA SPPL2C

3.62e-0465411412GO:0008233
GeneOntologyMolecularFunctionopsonin binding

CFH CR1 PTX3

3.80e-04251143GO:0001846
GeneOntologyMolecularFunctioncomplement binding

CFH CR1 PTX3

7.97e-04321143GO:0001848
GeneOntologyMolecularFunctionglycosaminoglycan binding

CFH FN1 RSPO4 F11 ITIH2 TENM1 ADGRE5

8.81e-042681147GO:0005539
GeneOntologyMolecularFunctionmercury ion binding

FN1 P2RX2

8.85e-0481142GO:0045340
GeneOntologyCellularComponentcell surface

CFH PRSS8 LRRC32 RAET1G ITGA4 CR1 CLSTN1 TF ST14 ADGRG6 MELTF BMPR2 SCUBE1 CD6 MUC17 P2RX2 CD163L1 SCARA5 ADGRE3 VAMP7 ADGRE5 IL23R ADGRA3

4.53e-08111111723GO:0009986
GeneOntologyCellularComponentextracellular matrix

PRSS3 FN1 ITLN1 LRRC32 CELA2A CELA2B ECM1 SSPOP TF ITIH2 ITIH3 TGM2 MUC17 OTOGL PTX3 LOXL2

7.84e-0765611716GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

PRSS3 FN1 ITLN1 LRRC32 CELA2A CELA2B ECM1 SSPOP TF ITIH2 ITIH3 TGM2 MUC17 OTOGL PTX3 LOXL2

8.16e-0765811716GO:0030312
GeneOntologyCellularComponentside of membrane

CFH PRSS8 ITLN1 LRRC32 LRRK2 RAET1G ITGA4 CR1 ST14 JAK2 MELTF SCUBE1 MUC17 CD163L1 ADGRE5 SPPL2C IL23R ADGRA3

1.75e-0687511718GO:0098552
GeneOntologyCellularComponentexternal side of plasma membrane

CFH PRSS8 LRRC32 RAET1G ITGA4 CR1 ST14 SCUBE1 MUC17 CD163L1 ADGRE5 IL23R ADGRA3

6.90e-0651911713GO:0009897
GeneOntologyCellularComponentcollagen-containing extracellular matrix

PRSS3 FN1 ITLN1 CELA2A CELA2B ECM1 SSPOP TF ITIH2 ITIH3 TGM2 MUC17 LOXL2

8.64e-0653011713GO:0062023
GeneOntologyCellularComponentinterleukin-23 receptor complex

JAK2 IL23R

1.85e-0441172GO:0072536
GeneOntologyCellularComponentkeratohyalin granule

CELA2A CELA2B

3.07e-0451172GO:0036457
GeneOntologyCellularComponentblood microparticle

CFH FN1 TMPRSS13 TF ITIH2

1.31e-031441175GO:0072562
Domain-

TMPRSS13 MSR1 CD6 CD163L1 SCARA5 LOXL2

7.69e-092511563.10.250.10
DomainSR

TMPRSS13 MSR1 CD6 CD163L1 SCARA5 LOXL2

7.69e-09251156SM00202
DomainSRCR-like_dom

TMPRSS13 MSR1 CD6 CD163L1 SCARA5 LOXL2

9.95e-09261156IPR017448
DomainSRCR_1

TMPRSS13 MSR1 CD6 CD163L1 SCARA5 LOXL2

9.95e-09261156PS00420
DomainSRCR_2

TMPRSS13 MSR1 CD6 CD163L1 SCARA5 LOXL2

9.95e-09261156PS50287
DomainSRCR

TMPRSS13 MSR1 CD6 CD163L1 SCARA5 LOXL2

1.27e-08271156IPR001190
DomainSRCR

MSR1 CD6 CD163L1 SCARA5 LOXL2

1.53e-07211155PF00530
DomainTRYPSIN_HIS

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

2.36e-071031158IPR018114
DomainTRYPSIN_SER

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

2.95e-071061158PS00135
DomainTRYPSIN_HIS

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

3.17e-071071158PS00134
DomainPeptidase_S1A

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

4.83e-071131158IPR001314
DomainTRYPSIN_DOM

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

5.53e-071151158PS50240
DomainTryp_SPc

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

6.31e-071171158SM00020
DomainTrypsin_dom

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

8.15e-071211158IPR001254
DomainTrypsin

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

8.15e-071211158PF00089
DomainPeptidase_S1_PA

PRSS3 PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

9.24e-071231158IPR009003
DomainTRYPSIN_SER

PRSS8 TMPRSS13 CELA2A CELA2B F11 ST14 CFD

1.37e-06901157IPR033116
DomainGPS

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

1.96e-06341155SM00303
DomainGPS

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

2.27e-06351155PF01825
DomainGPS

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

2.62e-06361155PS50221
DomainGPS

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

3.02e-06371155IPR000203
Domain7tm_2

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

1.38e-05501155PF00002
DomainG_PROTEIN_RECEP_F2_2

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

1.38e-05501155PS00650
DomainGPCR_2_secretin-like

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

3.38e-05601155IPR000832
DomainGPCR_2-like

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

3.38e-05601155IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

3.66e-05611155PS50261
DomainGPCR_2_secretin-like_CS

ADGRG6 ADGRE3 ADGRE5 ADGRF3

5.48e-05341154IPR017983
DomainEGF_3

SCARF2 SSPOP TENM2 SCUBE1 MUC17 ADGRE3 TENM1 ADGRE5

1.04e-042351158PS50026
DomainTransferrin

TF MELTF

1.12e-0431152PF00405
DomainTransferrin

TF MELTF

1.12e-0431152IPR016357
DomainTRANSFERRIN_LIKE_4

TF MELTF

1.12e-0431152PS51408
DomainTRANSFERRIN_LIKE_1

TF MELTF

1.12e-0431152PS00205
DomainTRANSFERRIN_LIKE_2

TF MELTF

1.12e-0431152PS00206
DomainTRANSFERRIN_LIKE_3

TF MELTF

1.12e-0431152PS00207
DomainTransferrin_Fe_BS

TF MELTF

1.12e-0431152IPR018195
DomainTR_FER

TF MELTF

1.12e-0431152SM00094
DomainTransferrin-like_dom

TF MELTF

1.12e-0431152IPR001156
DomainLamGL

PTX3 PAPPA

2.24e-0441152SM00560
DomainTox-GHH_dom

TENM2 TENM1

2.24e-0441152IPR028916
DomainLamG-like

PTX3 PAPPA

2.24e-0441152IPR006558
DomainTox-GHH

TENM2 TENM1

2.24e-0441152PF15636
DomainTen_N

TENM2 TENM1

2.24e-0441152IPR009471
DomainTen_N

TENM2 TENM1

2.24e-0441152PF06484
DomainTENEURIN_N

TENM2 TENM1

2.24e-0441152PS51361
DomainSushi

CFH CR1 F13B PAPPA

2.94e-04521154PF00084
DomainCCP

CFH CR1 F13B PAPPA

3.40e-04541154SM00032
DomainYD

TENM2 TENM1

3.71e-0451152IPR006530
DomainSPIN/Ssty

SPIN1 SPIN3

3.71e-0451152IPR003671
DomainSpin-Ssty

SPIN1 SPIN3

3.71e-0451152PF02513
DomainSUSHI

CFH CR1 F13B PAPPA

3.91e-04561154PS50923
DomainSushi_SCR_CCP_dom

CFH CR1 F13B PAPPA

4.19e-04571154IPR000436
DomainITI_HC_C

ITIH2 ITIH3

5.55e-0461152IPR010600
DomainITI_HC_C

ITIH2 ITIH3

5.55e-0461152PF06668
DomainEGF

SCARF2 TENM2 SCUBE1 MUC17 ADGRE3 TENM1 ADGRE5

6.33e-042351157SM00181
DomainEGF-like_dom

SCARF2 TENM2 SCUBE1 MUC17 ADGRE3 TENM1 ADGRE5

8.89e-042491157IPR000742
DomainEGF_1

FN1 SCARF2 SSPOP TENM2 SCUBE1 MUC17 TENM1

1.02e-032551157PS00022
DomainVIT

ITIH2 ITIH3

1.03e-0381152PF08487
DomainVIT

ITIH2 ITIH3

1.03e-0381152SM00609
DomainVIT

ITIH2 ITIH3

1.64e-03101152PS51468
DomainPTX

ADGRG6 PTX3

1.64e-03101152SM00159
DomainVIT

ITIH2 ITIH3

1.64e-03101152IPR013694
DomainGPCR_2_extracellular_dom

ADGRG6 ADGRF3 ADGRA3

1.90e-03401153IPR001879
DomainG_PROTEIN_RECEP_F2_1

ADGRG6 ADGRF3 ADGRA3

1.90e-03401153PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRG6 ADGRF3 ADGRA3

1.90e-03401153PS50227
DomainPentaxin-related

ADGRG6 PTX3

1.99e-03111152IPR001759
DomainPentaxin

ADGRG6 PTX3

1.99e-03111152PF00354
DomainGrowth_fac_rcpt_

SCARF2 RSPO4 SCUBE1 ADGRE3 ADGRE5

2.80e-031561155IPR009030
DomainNHL

TENM2 TENM1

2.80e-03131152PS51125
Domain-

CLSTN1 ADGRG6 PTX3 PAPPA

2.82e-039511542.60.120.200
Domain-

TMPRSS13 SSPOP ST14

2.85e-034611534.10.400.10
DomainLDLRA_1

TMPRSS13 SSPOP ST14

3.21e-03481153PS01209
DomainCUB

ST14 ADGRG6 SCUBE1

3.41e-03491153PF00431
DomainLDrepeatLR_classA_rpt

TMPRSS13 SSPOP ST14

3.41e-03491153IPR002172
DomainLDLa

TMPRSS13 SSPOP ST14

3.41e-03491153SM00192
DomainLDLRA_2

TMPRSS13 SSPOP ST14

3.41e-03491153PS50068
DomainCUB

ST14 ADGRG6 SCUBE1

3.61e-03501153SM00042
Domain-

ST14 ADGRG6 SCUBE1

4.04e-035211532.60.120.290
DomainCUB

ST14 ADGRG6 SCUBE1

4.26e-03531153PS01180
DomainSulfatase_CS

ARSD ARSF

4.26e-03161152IPR024607
DomainSULFATASE_1

ARSD ARSF

4.81e-03171152PS00523
DomainSULFATASE_2

ARSD ARSF

4.81e-03171152PS00149
DomainCUB_dom

ST14 ADGRG6 SCUBE1

5.23e-03571153IPR000859
DomainSulfatase

ARSD ARSF

5.39e-03181152PF00884
DomainSulfatase_N

ARSD ARSF

5.39e-03181152IPR000917
DomainEGF-like_CS

FN1 SCARF2 TENM2 SCUBE1 MUC17 TENM1

5.57e-032611156IPR013032
DomainEGF_2

SCARF2 SSPOP TENM2 SCUBE1 MUC17 TENM1

5.99e-032651156PS01186
DomainCyclophilin-type_PPIase_CS

RANBP2 PPIL1

6.00e-03191152IPR020892
Pubmed

Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.

CFH FN1 TF ITIH2 F13B CFD

4.96e-0859117617330941
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRG6 ADGRE3 ADGRE5 ADGRF3 ADGRA3

8.70e-0833117525713288
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

PRSS3 FN1 CELA2A CELA2B ECM1 SSPOP TGM2 LOXL2

1.50e-07175117828071719
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

CFH FN1 ECM1 TF F11 ITIH2 ITIH3 F13B ADGRG6

2.36e-07257117916335952
Pubmed

Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

CFH FN1 ITIH2 ITIH3 F13B CFD

2.49e-0777117616944957
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

PRSS8 FN1 ITLN1 LRRK2 CR1 SHROOM2 TF F11 CRK ADH5 CFD TGM2 MELTF ARSF RAB43 VAMP7

3.19e-0710161171619056867
Pubmed

Defect of hepatocyte growth factor activator inhibitor type 1/serine protease inhibitor, Kunitz type 1 (Hai-1/Spint1) leads to ichthyosis-like condition and abnormal hair development in mice.

PRSS8 ST14 CRK

7.37e-076117318832587
Pubmed

The DNA-binding activity of transcription factor PTF1 parallels the synthesis of pancreas-specific mRNAs during mouse development.

PRSS3 CELA2A CELA2B

1.29e-06711732294404
Pubmed

Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes.

PRSS3 CELA2A CELA2B

1.29e-06711733641189
Pubmed

Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation.

CFH CR1 CFD

1.29e-067117328057640
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

CFH FN1 CLSTN1 ECM1 ITIH2 PTX3 LOXL2 PAPPA

2.09e-06248117824006456
Pubmed

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

ITLN1 LRRK2 JAK2 IL23R

2.34e-0628117418587394
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRG6 ADGRE3 ADGRF3 ADGRA3

2.71e-0629117415203201
Pubmed

Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis.

ITLN1 LRRK2 JAK2 IL23R

3.57e-0631117421072187
Pubmed

Developmentally regulated transcription of the four liver-specific genes for inter-alpha-inhibitor family in mouse.

TF ITIH2 ITIH3

6.00e-061111737504460
Pubmed

Analysis of 39 Crohn's disease risk loci in Swedish inflammatory bowel disease patients.

ITLN1 LRRK2 JAK2 IL23R

9.13e-0639117419760754
Pubmed

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells.

FN1 TGM2

1.12e-052117221368175
Pubmed

Binding of the long pentraxin PTX3 to factor H: interacting domains and function in the regulation of complement activation.

CFH PTX3

1.12e-052117219050261
Pubmed

Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells.

CRK CTTN

1.12e-052117215263018
Pubmed

Transglutaminase 2 strongly binds to an extracellular matrix component other than fibronectin via its second C-terminal beta-barrel domain.

FN1 TGM2

1.12e-052117227685605
Pubmed

Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells.

PRSS8 ST14

1.12e-052117222582115
Pubmed

Insights into the regulation of the matriptase-prostasin proteolytic system.

PRSS8 ST14

1.12e-052117233094801
Pubmed

Assignment of complement components C4 binding protein (C4BP) and factor H (FH) to human chromosome 1q, using cDNA probes.

CFH CR1

1.12e-05211722977721
Pubmed

alpha4 Integrin/FN-CS1 mediated leukocyte adhesion to brain microvascular endothelial cells under flow conditions.

FN1 ITGA4

1.12e-052117219345424
Pubmed

Transglutaminase-2 interaction with heparin: identification of a heparin binding site that regulates cell adhesion to fibronectin-transglutaminase-2 matrix.

FN1 TGM2

1.12e-052117222442151
Pubmed

Circulating activated factor XI and active tissue factor as predictors of worse prognosis in patients following ischemic cerebrovascular events.

TF F11

1.12e-052117221820158
Pubmed

Elastase-2, a Tissue Alternative Pathway for Angiotensin II Generation, Plays a Role in Circulatory Sympathovagal Balance in Mice.

CELA2A CELA2B

1.12e-052117228386233
Pubmed

A matriptase-prostasin reciprocal zymogen activation complex with unique features: prostasin as a non-enzymatic co-factor for matriptase activation.

PRSS8 ST14

1.12e-052117223673661
Pubmed

Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms.

FN1 LOXL2

1.12e-052117231759052
Pubmed

Involvement of tissue transglutaminase in the stabilisation of biomaterial/tissue interfaces important in medical devices.

FN1 TGM2

1.12e-052117211829448
Pubmed

Inactivity of recombinant ELA2B provides a new example of evolutionary elastase silencing in humans.

CELA2A CELA2B

1.12e-052117216327289
Pubmed

Up-regulation of fibronectin and tissue transglutaminase promotes cell invasion involving increased association with integrin and MMP expression in A431 cells.

FN1 TGM2

1.12e-052117221036738
Pubmed

Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.

PRSS8 ST14

1.12e-052117223443662
Pubmed

Co-localization of the channel activating protease prostasin/(CAP1/PRSS8) with its candidate activator, matriptase.

PRSS8 ST14

1.12e-052117217471493
Pubmed

Cell-surface transglutaminase promotes fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: a role in TGFbeta-dependent matrix deposition.

FN1 TGM2

1.12e-052117211686302
Pubmed

Evaluating the performance of fibronectin 1 (FN1), integrin α4β1 (ITGA4), syndecan-2 (SDC2), and glycoprotein CD44 as the potential biomarkers of oral squamous cell carcinoma (OSCC).

FN1 ITGA4

1.12e-052117223116545
Pubmed

Characterization of pancreatic elastase II cDNAs: two elastase II mRNAs are expressed in human pancreas.

CELA2A CELA2B

1.12e-05211723646943
Pubmed

Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice.

PRSS8 ST14

1.12e-052117217940283
Pubmed

Dissecting the interaction between transglutaminase 2 and fibronectin.

FN1 TGM2

1.12e-052117227394141
Pubmed

Strong expression association between matriptase and its substrate prostasin in breast cancer.

PRSS8 ST14

1.12e-052117221678412
Pubmed

Transport via the transcytotic pathway makes prostasin available as a substrate for matriptase.

PRSS8 ST14

1.12e-052117221148558
Pubmed

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas.

PRSS3 CELA2A CELA2B

2.01e-051611739851981
Pubmed

Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease.

ITLN1 ECM1 IL23R

2.01e-0516117320014019
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FN1 ITLN1 ECM1 ITIH2 ITIH3 TGM2

2.26e-05167117622159717
Pubmed

Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk.

ECM1 JAK2 IL23R

2.44e-0517117319861958
Pubmed

Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity.

PRSS8 ST14

3.36e-053117237830556
Pubmed

Apoptotic death of hematopoietic tumor cells through potentiated and sustained adhesion to fibronectin via VLA-4.

FN1 ITGA4

3.36e-053117220007695
Pubmed

Regulation of the matriptase-prostasin cell surface proteolytic cascade by hepatocyte growth factor activator inhibitor-1 during epidermal differentiation.

PRSS8 ST14

3.36e-053117220696767
Pubmed

The interaction of angiocidin with tissue transglutaminase.

FN1 TGM2

3.36e-053117219931242
Pubmed

Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus Oocytes.

PRSS8 ST14

3.36e-053117212149280
Pubmed

Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI.

ITIH2 ITIH3

3.36e-05311722446322
Pubmed

Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3.

CFH PTX3

3.36e-053117222786770
Pubmed

The three heavy-chain precursors for the inter-alpha-inhibitor family in mouse: new members of the multicopper oxidase protein group with differential transcription in liver and brain.

ITIH2 ITIH3

3.36e-05311727534067
Pubmed

The RGD motif in fibronectin is essential for development but dispensable for fibril assembly.

FN1 ITGA4

3.36e-053117217591922
Pubmed

Inhibition of transglutaminase 2 reduces efferocytosis in human macrophages: Role of CD14 and SR-AI receptors.

MSR1 TGM2

3.36e-053117227378395
Pubmed

Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow.

FN1 TGM2

3.36e-053117228387755
Pubmed

Transglutaminase 2 and Factor XIII catalyze distinct substrates in differentiating osteoblastic cell line: utility of highly reactive substrate peptides.

F13B TGM2

3.36e-053117222045386
Pubmed

Identification by shotgun sequencing, genomic organization, and functional analysis of a fourth arylsulfatase gene (ARSF) from the Xp22.3 region.

ARSD ARSF

3.36e-05311729192838
Pubmed

The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network.

LRRC32 LRRK2

3.36e-053117232375042
Pubmed

Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera.

JAK2 PTX3

3.36e-053117228228104
Pubmed

A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.

CFH CR1

3.36e-05311723782802
Pubmed

C-reactive protein and pentraxin-3 binding of factor H-like protein 1 differs from complement factor H: implications for retinal inflammation.

CFH PTX3

3.36e-053117229374201
Pubmed

Evidence for a matriptase-prostasin proteolytic cascade regulating terminal epidermal differentiation.

PRSS8 ST14

3.36e-053117216980306
Pubmed

Differential induction of gelatinase B (MMP-9) and gelatinase A (MMP-2) in T lymphocytes upon alpha(4)beta(1)-mediated adhesion to VCAM-1 and the CS-1 peptide of fibronectin.

FN1 ITGA4

3.36e-053117211010812
Pubmed

VLA-5-mediated adhesion to fibronectin accelerates hemin-stimulated erythroid differentiation of K562 cells through induction of VLA-4 expression.

FN1 ITGA4

3.36e-053117219460753
Pubmed

ITIH5, a novel member of the inter-alpha-trypsin inhibitor heavy chain family is downregulated in breast cancer.

ITIH2 ITIH3

3.36e-053117214744536
Pubmed

Mesangial immune complex glomerulonephritis due to complement factor D deficiency.

CFH CFD

3.36e-053117217410102
Pubmed

C3(H2O) prevents rescue of complement-mediated C3 glomerulopathy in Cfh-/- Cfd-/- mice.

CFH CFD

3.36e-053117232376801
Pubmed

Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes.

CFH CR1

3.36e-053117220702729
Pubmed

Matriptase drives early-onset intestinal failure in a mouse model of congenital tufting enteropathy.

PRSS8 ST14

3.36e-053117231628112
Pubmed

Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35).

CFH CR1

3.36e-05311729988761
Pubmed

Investigation of IL23R, JAK2, and STAT3 gene polymorphisms and gene-gene interactions in Crohn's disease and ulcerative colitis in a Turkish population.

JAK2 IL23R

3.36e-053117227852544
Pubmed

Fibronectin 1 derived from tumor-associated macrophages and fibroblasts promotes metastasis through the JUN pathway in hepatocellular carcinoma.

FN1 KIF13A

3.36e-053117236461607
Pubmed

Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development.

FN1 ITGA4

3.36e-05311727539359
Pubmed

Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan.

ITIH2 ITIH3

3.36e-05311722476436
Pubmed

Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA.

CELA2A CELA2B

3.36e-05311723427074
Pubmed

A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy.

ARSD ARSF

3.36e-05311727720070
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

CFH LPCAT4 CLSTN1 ECM1 TGM2 MELTF BMPR2 P4HTM MGST3 LOXL2 IFI30 ADGRE5 QSOX2 ADGRA3

5.34e-0512011171435696571
Pubmed

Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.

CFH CR1

6.70e-054117227165610
Pubmed

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

TENM2 TENM1

6.70e-054117210225957
Pubmed

Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide.

SCARF2 MSR1

6.70e-054117215145948
Pubmed

Two sides of MGP null arterial disease: chondrogenic lesions dependent on transglutaminase 2 and elastin fragmentation associated with induction of adipsin.

CFD TGM2

6.70e-054117224036114
Pubmed

Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin.

PRSS8 ST14

6.70e-054117229438412
Pubmed

Importance of syndecan-4 and syndecan -2 in osteoblast cell adhesion and survival mediated by a tissue transglutaminase-fibronectin complex.

FN1 TGM2

6.70e-054117221036168
Pubmed

Regulated expression of tissue transglutaminase in Swiss 3T3 fibroblasts: effects on the processing of fibronectin, cell attachment, and cell death.

FN1 TGM2

6.70e-05411729511731
Pubmed

Delineation of proteolytic and non-proteolytic functions of the membrane-anchored serine protease prostasin.

PRSS8 ST14

6.70e-054117227385010
Pubmed

The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair?

ITIH2 ITIH3

6.70e-054117210100603
Pubmed

Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes.

ITIH2 ITIH3

6.70e-05411722465147
Pubmed

Dual functions of [alpha]4[beta]1 integrin in epicardial development: initial migration and long-term attachment.

FN1 ITGA4

6.70e-054117212021259
Pubmed

The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin.

PRSS8 ST14

6.70e-054117224962579
Pubmed

Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1.

PRSS8 ST14

6.70e-054117216524950
Pubmed

Hierarchies in the binding of human factor XIII, factor XIIIa, and endothelial cell transglutaminase to human plasma fibrinogen, fibrin, and fibronectin.

FN1 F13B

6.70e-05411728905624
Pubmed

The alpha 4 beta 1 fibronectin ligands CS-1, Hep II, and RGD induce different intracellular events in B lymphoid cells. Comparison with the effects of the endothelial ligand VCAM-1.

FN1 ITGA4

6.70e-05411729117345
Pubmed

Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement deposition.

CFH PTX3

6.70e-054117219632990
Pubmed

Mir-126 inhibits growth of SGC-7901 cells by synergistically targeting the oncogenes PI3KR2 and Crk, and the tumor suppressor PLK2.

PLK2 CRK

6.70e-054117224969300
Pubmed

EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation.

FN1 TGM2

6.70e-054117220080707
Pubmed

All four members of the Ten-m/Odz family of transmembrane proteins form dimers.

TENM2 TENM1

6.70e-054117212000766
Pubmed

Tissue transglutaminase mediates the pro-malignant effects of oncostatin M receptor over-expression in cervical squamous cell carcinoma.

FN1 TGM2

6.70e-054117223765377
Pubmed

In-depth proteomics analysis of sentinel lymph nodes from individuals with endometrial cancer.

PRSS3 PTX3

6.70e-054117234195683
Pubmed

Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling.

FN1 TGM2

6.70e-054117218499669
InteractionC3 interactions

CFH FN1 CR1 TF ITIH3 TGM2 LOXL2 PAPPA

3.01e-061551158int:C3
CytobandXp22.3

SHROOM2 ARSD ARSF

2.75e-05231173Xp22.3
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARF2 MSR1 CD163L1 SCARA5

7.01e-06278441253
GeneFamilyTransferrins

TF MELTF

6.38e-053842908
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFH CR1 F13B PAPPA

1.42e-04578441179
GeneFamilyProteases, serine

PRSS3 PRSS8 TMPRSS13 ST14

2.10e-0463844738
GeneFamilyTudor domain containing|Spindlin family

SPIN1 SPIN3

2.11e-0458421089
GeneFamilyCD molecules|Adhesion G protein-coupled receptors, subfamily E

ADGRE3 ADGRE5

2.11e-045842915
GeneFamilyComplement system|Sushi domain containing

CFH CR1 CFD

6.18e-0436843492
GeneFamilyTudor domain containing

SPIN1 SPIN3 TDRD12

6.71e-0437843780
GeneFamilyADAM metallopeptidase domain containing|CD molecules

PI16 ITGA4 CR1 MSR1 MELTF CD6 ADGRE5

2.38e-03394847471
GeneFamilySulfatases

ARSD ARSF

3.11e-0318842410
GeneFamilyCyclophilin peptidylprolyl isomerases

RANBP2 PPIL1

3.46e-0319842909
CoexpressionNABA_ECM_REGULATORS

PRSS3 CELA2A CELA2B ST14 ITIH2 ITIH3 F13B TGM2 P4HTM LOXL2 PAPPA

1.02e-0823811711M3468
CoexpressionNABA_ECM_REGULATORS

PRSS3 CELA2A CELA2B ST14 ITIH2 ITIH3 F13B TGM2 P4HTM LOXL2 PAPPA

1.22e-0824211711MM17062
CoexpressionNABA_MATRISOME

PRSS3 FN1 ITLN1 CELA2A RSPO4 CELA2B ECM1 SSPOP ST14 ITIH2 ITIH3 F13B TGM2 SCUBE1 P4HTM MUC17 OTOGL LOXL2 PAPPA

1.08e-07100811719MM17056
CoexpressionNABA_MATRISOME

PRSS3 FN1 ITLN1 CELA2A RSPO4 CELA2B ECM1 SSPOP ST14 ITIH2 ITIH3 F13B TGM2 SCUBE1 P4HTM MUC17 LOXL2 PAPPA

6.88e-07102611718M5889
CoexpressionDELYS_THYROID_CANCER_UP

PRSS3 FN1 PTPRU ECM1 ST14 MSR1 TGM2 LOXL2 IFI30 ADGRE5 CTTN MAP4K4

7.59e-0744511712M3645
CoexpressionNABA_MATRISOME_ASSOCIATED

PRSS3 ITLN1 CELA2A CELA2B ST14 ITIH2 ITIH3 F13B TGM2 SCUBE1 P4HTM MUC17 LOXL2 PAPPA

5.51e-0673811714MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

PRSS3 ITLN1 CELA2A CELA2B ST14 ITIH2 ITIH3 F13B TGM2 SCUBE1 P4HTM MUC17 LOXL2 PAPPA

6.72e-0675111714M5885
CoexpressionBERGER_MBD2_TARGETS

PRSS3 CELA2A CELA2B

1.39e-05111173MM905
CoexpressionSCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP

CFH FN1 RASSF2 MSR1 ARL4C TGM2 LOXL2 IFI30 MAP4K4

2.97e-053521179M17471
CoexpressionZHENG_FOXP3_TARGETS_IN_THYMUS_DN

PRSS3 TUBE1 MAP4K4

3.04e-05141173MM731
CoexpressionGSE27786_CD4_VS_CD8_TCELL_UP

ITGA4 ECM1 ST6GALNAC2 CD6 IFI30 MLLT6 ADGRE5

3.31e-052001177M4819
CoexpressionGSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_UP

DGKA ITGA4 ST14 ADGRG6 JAK2 AEBP2 IFI30

3.31e-052001177M7147
CoexpressionHALLMARK_COAGULATION

CFH FN1 TF F11 F13B CFD

3.70e-051381176M5946
CoexpressionZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST

PRSS3 FN1 CLSTN1 ECM1 TF ITIH2

4.01e-051401176MM1211
CoexpressionPARENT_MTOR_SIGNALING_UP

FN1 HECTD3 UPF1 CLSTN1 TF F11 JAK2 ARL4C MYO15B HEATR6 P4HTM

4.83e-0556711711M16909
CoexpressionLOPEZ_MBD_TARGETS

UIMC1 FN1 CELA2A UPF1 PTPRU ECM1 ITIH3 MEN1 SPIN1 ADGRE3 FDXR IFI30 PRKCG CTTN

9.12e-0595311714M4120
CoexpressionWALLACE_PROSTATE_CANCER_UP

PRSS8 POLD2 ST14

9.35e-05201173M3710
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_UP

FN1 ECM1 ST14 CRK TGM2 SPIN1

1.10e-041681176M1124
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_UP

FN1 ECM1 ST14 CRK TGM2 SPIN1

1.71e-041821176MM993
CoexpressionGSE34156_TLR1_TLR2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN

LAMP5 TGM2 SCUBE1 MYO15B HEATR6 ADGRE3

1.86e-041851176M8680
CoexpressionIL21_UP.V1_UP

ECM1 TF ST6GALNAC2 CFD CD6 PTX3

1.92e-041861176M2827
CoexpressionNABA_MATRISOME_HYPERPLASTIC_PANCREATIC_ISLETS

PRSS3 CELA2A CELA2B

2.09e-04261173MM17051
CoexpressionHOXA9_DN.V1_UP

PLK2 JAK2 ARL4C FDXR IFI30 MAP4K4

2.28e-041921176M2850
CoexpressionCHICAS_RB1_TARGETS_CONFLUENT

FN1 RASSF2 ITGA4 SHROOM2 ECM1 ADGRG6 ARL4C TGM2 PTX3 LOXL2

2.33e-0456711710M2129
CoexpressionLI_PBMC_MENACTRA_AGE_18_45YO_ANTI_DT_ANTIBODY_CORRELATION_PROFILE_3DY_UP

CR1 ST14 CFD

2.34e-04271173M40935
CoexpressionDI_MARTINO_MATRISOME_HIGHLY_PROLIFERATIVE_HNSCC

FN1 ECM1 ITIH2

2.34e-04271173M47994
CoexpressionAZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP

CFH PRSS3 PLK2 FN1 ARL4C

2.58e-041261175M2309
CoexpressionDACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP

RASSF2 TGM2 PTX3

2.62e-04281173M16941
CoexpressionGSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP

ARHGEF5 ECM1 ITIH3 ADH5 JAK2 ADGRE5

2.69e-041981176M8377
CoexpressionGSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_UP

RANBP2 DGKA CLSTN1 ARL4C TENM1 RBM6

2.76e-041991176M8324
CoexpressionGSE4811_CLASSSICALY_ACTIVATED_VS_TYPE_2_ACTIVATED_MACROPHAGE_UP

PNLIPRP2 PTPRU CLSTN1 UBE4A TENM1 TUBE1

2.76e-041991176M6547
CoexpressionONDER_CDH1_TARGETS_2_DN

PLK2 PRSS8 ARHGEF5 LPCAT4 ST14 ST6GALNAC2 ARL4C IFI30 ADGRA3

2.78e-044731179M4306
CoexpressionSTK33_NOMO_DN

POLD2 LRRK2 LAMP5 CR1 ST14 JPH1 FDXR

2.80e-042821177M2854
CoexpressionGSE19401_PAM2CSK4_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN

FN1 ECM1 ST14 ST6GALNAC2 CFD IFI30

2.84e-042001176M7668
CoexpressionGSE16266_CTRL_VS_LPS_STIM_MEF_DN

F11 ST6GALNAC2 PHKA2 MYO15B SCARA5 ADGRE5

2.84e-042001176M7212
CoexpressionLI_PBMC_MENOMUNE_A_C_Y_W_135_AGE_18_45YO_3DY_UP

CFH ST14 PTX3

2.91e-04291173M41150
CoexpressionNAKAMURA_CANCER_MICROENVIRONMENT_UP

PRSS3 LAMP5 CELA2B

2.91e-04291173M7581
CoexpressionZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST

FN1 CLSTN1 ECM1 TF ITIH2

3.09e-041311175M1687
ToppCellMesenchymal_cells-Arteriolar_fibro.|World / Lineage and Cell class

CFH FN1 PI16 SCARF2 ECM1 ITIH2 SCARA5 LOXL2

4.72e-081941178c1e8923a50b4138a1e4c054c0c17b7f7122aa8a9
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 CELA2B MSR1 CFD TGM2 MGST3 ADGRE3 IFI30

4.72e-081941178412c2b8eb522da6c84f8b00d32d6f0bee555251f
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH FN1 PI16 ECM1 CFD P2RX2 PTX3 SCARA5

5.97e-082001178f6cf98aad53aa8b3fa02cf874d6f7cd75530a213
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 LRRC32 TF TRIM52 TGM2 SCUBE1 LOXL2

2.89e-0716611779d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCellfacs-Lung-EPCAM-24m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 RASSF2 ITGA4 JAK2 AEBP2 IFI30 MLLT6

4.81e-07179117751872338e54c5f3e42ca9f1c4cf1e8b0cb84afcc
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASSF2 ITGA4 JAK2 AEBP2 IFI30 MLLT6 MAP4K4

6.01e-07185117719fa853f6f746ccf232a343b3c9c7a5e55800409
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac|normal_Pleural_Fluid / Location, Cell class and cell subclass

FOXN2 FN1 ECM1 MSR1 ADGRE3 IFI30 KIF13A

6.23e-0718611773314def702fe6a5056d0dadbb3a587c5d1a16412
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CELA2A MSR1 CFD MGST3 ADGRE3 IFI30 ACSBG2

6.23e-071861177cb7df8da6478b96955f3ef1394a0655ec8061bba
ToppCellFrontal_cortex-Endothelial|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CFH FN1 ARHGEF5 LRRC32 ECM1 TGM2 ADGRE5

6.69e-071881177a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCellSubstantia_nigra-Endothelial|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CFH SCARF2 ARHGEF5 LRRC32 ECM1 TGM2 ADGRE5

6.94e-071891177bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 CELA2B MSR1 TGM2 ADGRE3 IFI30 ADGRE5

6.94e-071891177a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCellGlobus_pallidus-Endothelial|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CFH ARHGEF5 LRRC32 ECM1 TGM2 LOXL2 ADGRE5

6.94e-071891177ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 LRRC32 ECM1 PTX3 SCARA5 LOXL2

7.19e-071901177bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 LRRC32 ECM1 PTX3 SCARA5 LOXL2

7.19e-071901177e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 LRRC32 ECM1 PTX3 SCARA5 LOXL2

7.19e-071901177ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH FN1 PI16 ECM1 CFD PTX3 SCARA5

7.71e-071921177f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH FN1 PI16 ECM1 CFD PTX3 SCARA5

7.71e-07192117741a8326cd5bc19ad5041068501bab4c72399222e
ToppCellHippocampus-Endothelial|Hippocampus / BrainAtlas - Mouse McCarroll V32

CFH ARHGEF5 LRRC32 ECM1 TGM2 LOXL2 ADGRE5

7.71e-07192117736deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

CFH FN1 PI16 ECM1 CFD SCARA5 PAPPA

8.26e-071941177014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH FN1 PI16 ECM1 CFD PTX3 SCARA5

8.55e-07195117747762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 FN1 SCARF2 ECM1 TGM2 LOXL2 PAPPA

8.55e-071951177095b8e0be385b6390420589124a95fa4ba3682ab
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 CELA2B MSR1 CFD MGST3 ADGRE3 IFI30

8.85e-071961177eb7d6bbfb766cdeaf5fe0f0bb66a5f491fd5ef26
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 CELA2B MSR1 CFD MGST3 ADGRE3 IFI30

8.85e-0719611772793ad692d49b3ee78a5cd2d8e0220bf5188a686
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 CELA2B MSR1 CFD MGST3 ADGRE3 IFI30

8.85e-071961177aae79eafe5bc2c7de16958994a2fe97439d7bea1
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH FN1 ECM1 CFD SCARA5 LOXL2 PAPPA

9.47e-0719811777582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLK2 FN1 LRRC32 ADGRG6 TGM2 BMPR2 SCUBE1

9.47e-071981177259fbcc0f2ac281a3e4d693de45b986fe5e24841
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH PLK2 FN1 PI16 LRRC32 TGM2 BMPR2

9.80e-07199117733f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCell390C-Fibroblasts-Fibroblast-H-|390C / Donor, Lineage, Cell class and subclass (all cells)

CFH FN1 RSPO4 CFD PTX3 SCARA5 PAPPA

1.01e-062001177ec7d6a08e34bcad5b3bbff56ebef96ae17e4cefd
ToppCell343B-Fibroblasts|343B / Donor, Lineage, Cell class and subclass (all cells)

CFH FN1 PI16 ECM1 CFD TGM2 SCARA5

1.01e-062001177376c1a77031e090be96948b47c78ac0d393f5775
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH FN1 PI16 ECM1 CFD P2RX2 SCARA5

1.01e-062001177cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial|2m / Sample Type, Dataset, Time_group, and Cell type.

CFH FN1 ITGA4 ECM1 ITIH2 SCARA5 LOXL2

1.01e-0620011773da9441c0f1e242f0d195de47ecd4c24dfdca232
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial-Proteoglycan-expressing_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

CFH FN1 ITGA4 ECM1 ITIH2 SCARA5 LOXL2

1.01e-062001177eed2bafddcd041ef5fcc4d1d31edb8be4d83ce01
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

CFH FN1 PI16 SCARF2 ECM1 CFD SCARA5

1.01e-062001177f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCell390C-Fibroblasts-Fibroblast-H|390C / Donor, Lineage, Cell class and subclass (all cells)

CFH FN1 RSPO4 CFD PTX3 SCARA5 PAPPA

1.01e-062001177671e731977c58a0c44c36b56422085d93d999aad
ToppCell(01)_IL1RL1+|World / shred by cell type by condition

RAET1G ECM1 TENM2 ARL4C LOXL2 PAPPA MAP4K4

1.01e-062001177501420901bf3ec1b050e0d14596a9f9f3fdfc928
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

PI16 SCARF2 ITIH2 MELTF SCARA5 LOXL2

1.49e-061341176d29ac8152dc581c0da2430d06cd259ac0eded808
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

PI16 SCARF2 ITIH2 MELTF SCARA5 LOXL2

1.49e-061341176459c39df15d3cf9144ce7827e8d14830d31353bb
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

PI16 SCARF2 ITIH2 MELTF SCARA5 LOXL2

1.49e-061341176d065449ca3679e4818b74fb7302cc7f1ce62f691
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)|Cerebellum / BrainAtlas - Mouse McCarroll V32

PI16 SCARF2 ITIH2 MELTF SCARA5 LOXL2

1.49e-0613411760be389f416818a22e80098dd809fdf45b14171e8
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 UROC1 ITIH2 ITIH3 F13B

2.98e-061511176cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RASSF2 LAMP5 MLLT10 ST14 ADGRG6 TENM1

4.16e-061601176636127753e3a22831f39d4c8170df40901e4329d
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RASSF2 LAMP5 MLLT10 ST14 ADGRG6 TENM1

4.16e-061601176cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCelldroplet-Pancreas-Exocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 FN1 PNLIPRP2 TMPRSS13 CELA2A PTX3

4.96e-061651176c17e00ec9dbe30fcded65a461231dbb13665ddac
ToppCell15-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

PRSS8 ST14 ST6GALNAC2 MELTF P2RX2 LOXL2

5.89e-06170117661f8dd5e27df1b8d01ccfd0d25247b34aa8d182c
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

LRRC32 LAMP5 ECM1 ADGRG6 CD163L1 LOXL2

5.89e-061701176d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCelldroplet-Fat-Scat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 MSR1 ARL4C CFD PTX3 IFI30

5.89e-061701176de722bea7527d6ad11b69f8e9589638f52854beb
ToppCellTCGA-Liver|World / Sample_Type by Project: Shred V9

UROC1 TF F11 ITIH2 ITIH3 F13B

6.73e-061741176452932f08cf53e5949672a025d78cecb874aa4b0
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

CFH UROC1 TF F11 ITIH2 ITIH3

6.73e-0617411765aa2fb631505600f37d2b87b02def7be139dc262
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

UROC1 TF F11 ITIH2 ITIH3 F13B

6.95e-0617511767f74961436f88c0e380819095e6104489914d765
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

UROC1 TF F11 ITIH2 ITIH3 F13B

6.95e-061751176bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

FN1 LAMP5 ECM1 ST14 ARL4C CD163L1

7.42e-061771176470f54fe2b21c7350ea471e02039461a3808f700
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRSS3 PRSS8 CELA2B PTPRU ST14 MELTF

7.42e-0617711761f5b6498364b2017c4d49cd337d6e91c8e4f840d
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASSF2 ITGA4 JAK2 AEBP2 IFI30 MLLT6

7.91e-0617911761b979e0203a2ddfe98bf6c2c80c4af1ba437a80f
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 SCARF2 LAMP5 ECM1 LOXL2 PAPPA

8.17e-061801176935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell5'-Airway_Nasal-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 SCARF2 LAMP5 ECM1 LOXL2 PAPPA

8.17e-0618011763dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 PI16 SCARF2 ECM1 SCARA5 LOXL2

8.17e-061801176f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 FN1 PNLIPRP2 CELA2A OTOGL PTX3

8.17e-06180117672310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 PNLIPRP2 CELA2A TENM2 ST14 MGST3

8.70e-061821176b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 PNLIPRP2 CELA2A TENM2 ST14 MGST3

8.70e-061821176cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 SCARF2 LAMP5 ECM1 LOXL2 PAPPA

8.97e-061831176803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 SCARF2 LAMP5 ECM1 LOXL2 PAPPA

8.97e-0618311766d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 SCARF2 LAMP5 ECM1 LOXL2 PAPPA

8.97e-061831176cc7f5a17b40e8d901885174922e5fa8877643071
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

CFH ITLN1 RAET1G ADGRG6 CTTN ADGRA3

9.55e-06185117623579988036fc1925992c31919750f9b3fe9f790
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 PI16 ECM1 PTX3 SCARA5 LOXL2

9.84e-061861176a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCellfacs-Trachea-nan-24m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 PI16 ECM1 PTX3 SCARA5

1.01e-05187117671385068e3fd0bfa7822ae176113a49460c8636b
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 PRSS8 PNLIPRP2 CELA2A ADGRG6 TGM2

1.01e-0518711769aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRRK2 CR1 CFD PTX3 ADGRE3 IFI30

1.01e-0518711763b1439018e265a61d9599e307a202e3c2f60ed32
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRRK2 CR1 CFD PTX3 ADGRE3 IFI30

1.01e-051871176e99bc27d212c74da37770297122a4b30445ccd0d
ToppCellfacs-Trachea-nan-24m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 PI16 ECM1 PTX3 SCARA5

1.01e-051871176e891e571f6bb9433a0046215de6cabd89ed1effc
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH UIMC1 PLK2 ECM1 ADH5 LOXL2

1.01e-05187117639756ab418267151d86f9c2553db859f71900bb1
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FN1 PI16 ECM1 PTX3 SCARA5 LOXL2

1.05e-051881176aa516273cdde53c8c0295f06830972388f890c97
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PRSS3 CR1 JPH1 CFD PTX3 ADGRE3

1.05e-051881176b4d695c373195d389e0a579e9589e87433286b24
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 PI16 ECM1 SCARA5 LOXL2

1.08e-051891176bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 PI16 ECM1 PTX3 SCARA5 LOXL2

1.08e-0518911760a8b827bba1efd885ad6c06929251c741dc3a541
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 PI16 ECM1 PTX3 SCARA5 LOXL2

1.08e-05189117656f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DGKA CLSTN1 TRAPPC13 ARL4C CD6 TENM1

1.08e-051891176e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCellStriatum-Endothelial|Striatum / BrainAtlas - Mouse McCarroll V32

CFH LRRC32 ITGA4 ECM1 TGM2 ADGRE5

1.08e-05189117695ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

CFH FN1 SHROOM2 ADGRG6 TGM2 BMPR2

1.08e-05189117675c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 PI16 ECM1 SCARA5 LOXL2

1.11e-051901176f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 PI16 ECM1 SCARA5 LOXL2

1.11e-051901176c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCelldroplet-Mammary_Gland-nan-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 PI16 ECM1 PTX3 SCARA5 LOXL2

1.14e-0519111768022059e434fd411dc539819f969bd4f94861281
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFH FN1 RSPO4 BMPR2 PAPPA ADGRA3

1.14e-05191117608720998aa55131d7377c4c67c4c935865bd7d79
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH FN1 PI16 ECM1 CFD SCARA5

1.14e-0519111760fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH FN1 PI16 ECM1 CFD SCARA5

1.18e-051921176b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell390C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CELA2B MSR1 CFD TGM2 IFI30 SIGLEC11

1.21e-051931176c9cf5a661294a947d06d53d18d47362c0e0b6ef5
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRSS3 PRSS8 ST14 CFD MELTF MUC17

1.21e-05193117632eb026d4317c1499d51294d396dfd5f293f9deb
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH FN1 ABHD12B PI16 RASSF2 TENM2

1.21e-051931176549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRSS3 PRSS8 ST14 CFD MELTF MUC17

1.21e-051931176930df79b0600f43617052313294be33bcf5631f0
ToppCellfacs-Pancreas-Exocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 PNLIPRP2 CELA2A ST6GALNAC2 ADGRG6 TGM2

1.21e-051931176c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FN1 PI16 ECM1 SCARA5 LOXL2

1.21e-051931176160691b671710be10220803d788c2c961c236af1
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FN1 PI16 ECM1 PTX3 SCARA5 LOXL2

1.25e-0519411767b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

CFH FN1 PI16 CFD SCARA5 PAPPA

1.25e-051941176d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellRA|World / Chamber and Cluster_Paper

CFH FN1 CFD TGM2 OTOGL PAPPA

1.25e-05194117608f0afbb68a63150fbe107a5337299081c3f69e4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFH LPCAT4 ARL4C CD6 MLLT6 IL23R

1.29e-051951176e173a713d273b135db4f71bdcaada3b0e55d74f1
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 MSR1 CFD MGST3 IFI30 ADGRE5

1.29e-051951176c264b052bc50c5bd92816e12fbbe08014d2002f4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFH LPCAT4 ARL4C CD6 MLLT6 IL23R

1.29e-05195117659164d115a0928cc9b79c7661c7190ad695f9d80
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH PI16 ECM1 MELTF SCARA5 LOXL2

1.29e-0519511760feb6ebe7b4b781dec7cfaef844140cfbf84b4b9
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH PI16 ECM1 MELTF SCARA5 LOXL2

1.29e-0519511762a6f67875cef140b0e6b8401436719675c6b3665
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 MSR1 CFD MGST3 IFI30 ADGRE5

1.29e-051951176f5351932634d5913688b15f16da76198c91e9b53
ToppCellPosterior_cortex-Endothelial|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CFH ARHGEF5 LRRC32 ECM1 TGM2 ADGRE5

1.29e-051951176988e3449691cc228cb55e5e30355136c97b12262
ComputationalPlacenta genes.

PRSS8 FN1 LRRC32 DGKA PTPRU ECM1 ADGRG6 MEN1 ARL4C CFD TGM2 FDXR ADGRE5

1.03e-054637213MODULE_38
ComputationalNeighborhood of SERPINI2

PRSS3 PNLIPRP2 CELA2A CELA2B

2.10e-0525724GNF2_SERPINI2
ComputationalSerine proteases.

PRSS8 CELA2A CELA2B F11

1.27e-0439724MODULE_109
ComputationalTrachea genes.

CFH PRSS8 FN1 DGKA PTPRU ADGRG6 MEN1 CFD TGM2 CD6

4.15e-044157210MODULE_6
ComputationalNeighborhood of CDH11

FN1 PTX3 LOXL2

5.96e-0425723GNF2_CDH11
ComputationalNeighborhood of SPINK1

PRSS3 PNLIPRP2 CELA2A

7.51e-0427723GNF2_SPINK1
Drug2gst

FN1 ADGRG6 CFD ADGRE3 ADGRE5 ADGRF3 ADGRA3

2.86e-07861167CID000444461
Diseaseangiogenic factor with G patch and FHA domains 1 measurement

CFH ITIH2

1.43e-0521122EFO_0802278
Diseasescavenger receptor class A member 5 measurement

CFH SCARA5

1.43e-0521122EFO_0802037
DiseaseCrohn Disease

FN1 LRRK2 JAK2 IL23R

3.96e-05501124C0010346
Diseasepotassium voltage-gated channel subfamily G member 4 measurement

CFH ITIH2

4.27e-0531122EFO_0802891
Diseaseprotocadherin beta-2 measurement

CFH ITIH2

4.27e-0531122EFO_0801975
DiseaseR-spondin-4 measurement

CFH RSPO4

4.27e-0531122EFO_0022019
Diseaseglucose-6-phosphate isomerase measurement

CFH CD163L1

4.27e-0531122EFO_0020407
Diseaseprotein YIPF6 measurement

CFH CFD

4.27e-0531122EFO_0802969
Diseasescavenger receptor class F member 2 measurement

CFH SCARF2

8.53e-0541122EFO_0020716
DiseaseB-cell antigen receptor complex-associated protein alpha chain measurement

CFH ITIH2

8.53e-0541122EFO_0801402
DiseaseMeningococcal Infections

CFH CFD

8.53e-0541122C0025303
Diseaseadhesion G protein-coupled receptor E2 measurement

CFH ADGRE5

8.53e-0541122EFO_0021892
DiseaseE3 ubiquitin-protein ligase RNF149 measurement

CFH CFD

8.53e-0541122EFO_0802511
Diseaserap guanine nucleotide exchange factor 5 measurement

CFH CFD

8.53e-0541122EFO_0802989
Diseasezinc transporter 3 measurement

CFH CFD

1.42e-0451122EFO_0803287
Diseasepotassium voltage-gated channel subfamily F member 1 measurement

CFH TF

1.42e-0451122EFO_0802890
Diseasetoll-like receptor 1 measurement

CFH CFD

1.42e-0451122EFO_0803159
Diseasetachykinin-4 measurement

CFH CFD

1.42e-0451122EFO_0803137
Diseaseserine/threonine-protein kinase Chk1 measurement

CFH CFD

1.42e-0451122EFO_0021965
Diseasemembrane-associated progesterone receptor component 2 measurement

CFH CFD

1.42e-0451122EFO_0801796
Diseasesingle Ig IL-1-related receptor measurement

CFH ITIH2

1.42e-0451122EFO_0802072
DiseaseCrohn's disease (is_implicated_in)

LRRK2 JAK2 IL23R

2.01e-04301123DOID:8778 (is_implicated_in)
Diseasepre-mRNA-processing factor 6 measurement

CFH CFD

2.12e-0461122EFO_0802894
DiseaseE3 ubiquitin-protein ligase RNF128 measurement

CFH CFD

2.12e-0461122EFO_0801555
Diseasethymidine kinase, cytosolic measurement

CFH CFD

2.12e-0461122EFO_0020773
Diseaserab9 effector protein with kelch motifs measurement

CFH CFD

2.12e-0461122EFO_0801984
Diseaseo-acetyl-ADP-ribose deacetylase MACROD1 measurement

CFH CFD

2.12e-0461122EFO_0802827
Diseasethioredoxin-interacting protein measurement

CFH CFD

2.12e-0461122EFO_0803149
Diseaseribosome biogenesis protein TSR3 homolog measurement

CFH CFD

2.12e-0461122EFO_0803025
DiseaseCCAAT/enhancer-binding protein beta measurement

CFH CFD

2.12e-0461122EFO_0021905
Diseaseleucine-rich repeat and fibronectin type III domain-containing protein 1 measurement

CFH CFD

2.12e-0461122EFO_0802689
Diseaseleucine-rich repeat-containing protein 74A measurement

CFH CFD

2.12e-0461122EFO_0801763
Diseaseinterleukin-23 receptor measurement

CFH IL23R

2.12e-0461122EFO_0801725
Diseasesecreted frizzled-related protein 2 measurement

CFH CFD

2.12e-0461122EFO_0802039
DiseaseDNA-binding protein SATB2 measurement

CFH CFD

2.12e-0461122EFO_0802484
Diseasemyotubularin-related protein 1 measurement

CFH CFD

2.96e-0471122EFO_0802773
Diseasekv channel-interacting protein 1 measurement

CFH CFD

2.96e-0471122EFO_0801751
DiseaseRNA polymerase II elongation factor ELL measurement

CFH CFD

2.96e-0471122EFO_0802028
Diseasevascular cell adhesion protein 1 measurement

CFH ITGA4

2.96e-0471122EFO_0020846
Diseasecytochrome c oxidase assembly factor 3 homolog, mitochondrial measurement

CFH CFD

3.94e-0481122EFO_0801513
Diseasegrowth factor receptor-bound protein 7 measurement

CFH CFD

3.94e-0481122EFO_0801659
Diseasetumor necrosis factor receptor superfamily member 19L measurement

CFH CFD

3.94e-0481122EFO_0008309
Diseasecytochrome c oxidase subunit 4 isoform 2, mitochondrial measurement

CFH CFD

5.05e-0491122EFO_0801514
DiseaseRNA-binding protein 24 measurement

CFH CFD

5.05e-0491122EFO_0802030
Diseasetranscription factor IIIb 90 kda subunit measurement

CFH CFD

6.30e-04101122EFO_0020778
DiseaseDNA-directed RNA polymerases I and III subunit RPAC1 measurement

CFH CFD

6.30e-04101122EFO_0801535
Diseaseprotein eva-1 homolog C measurement

CFH SCARA5

6.30e-04101122EFO_0801942
DiseaseOCIA domain-containing protein 1 measurement

CFH CFD

6.30e-04101122EFO_0008252
Diseasecytochrome p450 3a4 measurement

CFH CFD

7.68e-04111122EFO_0020303
Diseaseguanylate-binding protein 6 measurement

CFH CFD

7.68e-04111122EFO_0801662
DiseaseT-cell surface glycoprotein CD3 epsilon chain measurement

CFH CFD

1.08e-03131122EFO_0802114
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

CFH PTPRU

1.26e-03141122DOID:10976 (biomarker_via_orthology)
Diseasethrombosis (is_implicated_in)

F11 JAK2

1.45e-03151122DOID:0060903 (is_implicated_in)
Diseaseidiopathic scoliosis (implicated_via_orthology)

SSPOP ADGRG6

1.65e-03161122DOID:0060250 (implicated_via_orthology)
Diseasesarcoidosis (is_implicated_in)

CFH IL23R

1.65e-03161122DOID:11335 (is_implicated_in)
Diseasecathepsin L1 measurement

LRRK2 IFI30

1.65e-03161122EFO_0010619
Diseaseinflammatory bowel disease

ITLN1 LRRK2 ITGA4 JAK2 CD6 MAP4K4 IL23R

1.66e-034491127EFO_0003767
DiseaseUlcerative Colitis

ECM1 JAK2 IL23R

1.79e-03631123C0009324
DiseaseSLAM family member 7 measurement

CFH ITLN1

1.87e-03171122EFO_0008287
DiseaseAntibody Deficiency Syndrome

CFH CFD

1.87e-03171122C0003257
Diseaseulcerative colitis (is_implicated_in)

JAK2 IL23R

1.87e-03171122DOID:8577 (is_implicated_in)
DiseaseAcute myeloid leukemia

MLLT10 JAK2

1.87e-03171122cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

MLLT10 JAK2

1.87e-03171122601626
Diseaseankylosing spondylitis (is_implicated_in)

JAK2 IL23R

2.34e-03191122DOID:7147 (is_implicated_in)
Diseaseglomerulonephritis (is_marker_for)

FN1 TF

2.34e-03191122DOID:2921 (is_marker_for)
Diseaseautoimmune thyroid disease, systemic lupus erythematosus, type 1 diabetes mellitus, ankylosing spondylitis, psoriasis, common variable immunodeficiency, celiac disease, ulcerative colitis, Crohn's disease, autoimmune disease, juvenile idiopathic arthritis

LRRK2 JAK2 IL23R

2.42e-03701123EFO_0000384, EFO_0000676, EFO_0000729, EFO_0001060, EFO_0002609, EFO_0003898, EFO_0005140, EFO_0006812, MONDO_0005147, MONDO_0007915, MONDO_0015517
Diseaserheumatoid arthritis, ulcerative colitis

JAK2 IL23R

2.86e-03211122EFO_0000685, EFO_0000729
DiseaseDeep Vein Thrombosis

F13B JAK2

2.86e-03211122C0149871
Diseasetransferrin glycosylation measurement

TF MSR1

2.86e-03211122EFO_0021537
DiseaseVenous Thrombosis

F13B JAK2

2.86e-03211122C0042487
Diseasenephrosis (biomarker_via_orthology)

CFH PTPRU

3.14e-03221122DOID:2527 (biomarker_via_orthology)
DiseaseOvarian Serous Adenocarcinoma

LRRK2 JAK2

3.43e-03231122C1335177
DiseaseImmunologic Deficiency Syndromes

CFH CFD

3.43e-03231122C0021051

Protein segments in the cluster

PeptideGeneStartEntry
QVVWAKTERIGCGSH

PI16

131

Q6UXB8
DRQTKNGAKWHGGVS

nan

21

Q0VG73
IHRDQGECANQWRKG

nan

26

Q9HAA7
QNKDGIGEICLWGRH

ACSBG2

456

Q5FVE4
STGLIGKWHQGLNCD

ARSF

131

P54793
GKWHQGLNCDSRSDQ

ARSF

136

P54793
KRTDNGGWAHVVCAL

MLLT6

76

P55198
RGGWSKEGCQAQVAS

ADGRF3

726

Q8IZF5
HVDGQRGGVFVCLWK

AEBP2

286

Q6ZN18
YATGLIGKWHQGVNC

ARSD

141

P51689
IGKWHQGVNCASRGD

ARSD

146

P51689
NGTAKGISCHFWDVG

ARL4C

56

P56559
GISCHFWDVGGQEKL

ARL4C

61

P56559
NDGKVCLSILNTWHG

BIRC6

4661

Q9NR09
ACHKGWGVSVVVGVA

ADH5

281

P11766
NKSFGGWNTSGCVAH

ADGRG6

811

Q86SQ4
ISNIQAGSTGNWGCH

ADGRA3

311

Q8IWK6
AGSTGNWGCHVQTKR

ADGRA3

316

Q8IWK6
NWGCHVQTKRGNNTR

ADGRA3

321

Q8IWK6
HSGRCAFWGNVEVGR

FDXR

101

P22570
SEGANKHKGWSRQGL

ARHGEF5

1026

Q12774
VCLWGHSLGTGVATN

ABHD12B

211

Q7Z5M8
GHWATEGCQVLGSKN

ADGRE5

506

P48960
GCNGAAHLVRGDAWK

APRG1

126

Q8IVJ8
CRGKEGWIHTVCING

CFH

781

P08603
NCQASDGRWQVHGIV

CELA2A

221

P08217
LCGGGVWAARVNKHK

CLSTN1

21

O94985
GQVEINVLGHWGSLC

CD163L1

911

Q9NR16
VSGQWEGECNGKRGH

CRK

271

P46108
HGGCLVTRGTKWIAN

P4HTM

441

Q9NXG6
VHWAECLQKTGSGLN

RANBP2

576

P49792
HIQLNSKDIGEGWGC

RAB43

196

Q86YS6
WHSGCNLGAQGTTLK

RASSF2

86

P50749
GIFLTNHIKWVGCQG

QSOX2

406

Q6ZRP7
NHIKWVGCQGSRSEL

QSOX2

411

Q6ZRP7
TGNGGIQWSRGKHKE

JAK2

291

O60674
LIKHWCGTTGQPTQE

SLC34A3

271

Q8N130
VTWHGKGNEDRRGQT

MEN1

201

O00255
NGAHLCGGVLVAEQW

CFD

46

P00746
GAVCSEHQSWRLTGG

CD6

256

P30203
KQGWTTVGDLEGCVH

MAP4K4

1011

O95819
RGKCTVGDRWSSQQG

ITLN1

91

Q8WWA0
TTLDGHGGQCVTWLQ

GNB1L

61

Q9BYB4
ITGWRKTVCHNGVLG

LPCAT4

81

Q643R3
GTDVTCWFVHNSGKG

ITIH2

911

P19823
GEWANNKRHGYGCTV

JPH1

306

Q9HDC5
NGWGVTDCKHTEDVG

LOXL2

141

Q9Y4K0
GNQGSGWKAICLSHD

DCAF4L2

256

Q8NA75
ENRAQQHWGSGVGVK

POLD2

66

P49005
HGSNEITCNRGKWTL

F13B

371

P05160
GVQSHVWVRGGCESG

DGKA

266

P23743
TGTGRVNLHEGNTWC

HEATR6

346

Q6AI08
SIWLGCGHTDRGQLS

LRRK2

2166

Q5S007
VNHSWIERVFGKCGN

LARP7

136

Q4G0J3
KGRCGHSQSELQVFW

LAMP5

96

Q9UJQ1
HCTDFIWGIGKQGLQ

PRKCG

51

P05129
CSAFQHLGWVKSGLG

MGST3

131

O14880
LGSNVIHCRKDGTWN

PAPPA

1451

Q13219
GRVEILHSGQWGTIC

MSR1

361

P21757
KWQAESGDGRTIVHC

PTPRU

1366

Q92729
CGNGWLAAQLHQGRV

LRRC32

576

Q14392
EQRSGWHKGQLSNGE

MYO15B

1491

Q96JP2
AHKGGVIGVIINWDC

P2RX2

256

Q9UBL9
KKWFCNGRGNTSGSH

UPF1

141

Q92900
NCQASDGRWEVHGIG

CELA2B

221

P08218
VGSHTVQCQTNGRWG

CR1

1626

P17927
EQNVSGRWEFKCQHG

IFI30

106

P13284
TGNGRGEWKCERHTS

FN1

261

P02751
CHGGITNINCSGHIW

IL23R

21

Q5VWK5
DINLVKQGCWSHIGD

BMPR2

76

Q13873
TQRHLCGGSIIGNQW

F11

411

P03951
GENGSIVTCGHRWKN

ITGA4

136

P13612
SHGKVNGKGSLWCVD

FOXN2

176

P32314
CQQDRSQGGWGHRLD

ECM1

151

Q16610
GRRLHWNGKDCVETG

SCUBE1

391

Q8IWY4
KWGVTNCGHAEDASV

SCARA5

476

Q6ZMJ2
GGKRTVPWNCHTIQG

CCDC103

66

Q8IW40
CGTVVGDDQWGHLQV

PHKA2

121

P46019
WEGIGGFVSCNHLRS

PNLIPRP2

271

P54317
GNGRDGICKTWGQYH

OTOGL

116

Q3ZCN5
SCHIRGNIVGWGVTE

PTX3

356

P26022
DKEGRTALHWSCNNG

INVS

486

Q9Y283
QNTASRCKNGGTWDG

MUC17

4141

Q685J3
IEVWGHRCAGNGSSI

KIF13A

951

Q9H1H9
TSSKGGCVQQATGWR

RBM6

1051

P78332
GTWRDGNVVCVQSNH

TRMT2B

176

Q96GJ1
THNGKTCGSAWGLES

RSPO4

151

Q2I0M5
VDHELWGQTQGLCGL

SSPOP

311

A2VEC9
GVKSCHTGINRTVGW

MELTF

126

P08582
GQHLQCTGKIYGSVW

SAMD8

256

Q96LT4
AQSLQHTWCKGIVGD

TDRD12

266

Q587J7
GTKVVCWFVHNNGEG

ITIH3

861

Q06033
CWFVHNNGEGLIDGV

ITIH3

866

Q06033
CSFHTKGWLAQGQGA

SPPL2C

101

Q8IUH8
SNSWTGKGQACRHLL

ST6GALNAC2

56

Q9UJ37
ARQLGKQWAVLTCGH

SHPRH

1436

Q149N8
RGLSSCDQKLGSGWQ

SHROOM2

461

Q13796
GNGRCTLDQNGWHCV

TENM1

771

Q9UKZ4
WNGEHCTIGRQTAGT

TENM2

791

Q9NT68
GVHVCGGSLVSEQWV

PRSS8

66

Q16651
GNGLCGISHKEQEVW

SLC35F4

21

A4IF30
GQGSQWSRDGCFLIH

ADGRE3

311

Q9BY15
ALKRTDNGGWAHVVC

MLLT10

91

P55197
GSVDILRRWKNHGCQ

TGM2

256

P21980
GHNFCRGCVTQLWSK

TRIM52

36

Q96A61
LNGDICKWHRGGSNG

UCK1

231

Q9HA47
GTTHICGGTLIDAQW

TMPRSS13

346

Q9BYE2
KKSCHTAVGRTAGWN

TF

466

P02787
WLDGKHTIFGRVCQG

PPIL1

121

Q9Y3C6
EQRWGAKTVQGSGHQ

CTTN

36

Q14247
DISGSGNNWAVGHKV

TUBE1

101

Q9UJT0
CRGATWVALHNGGGV

UROC1

581

Q96N76
RNIVGCRIQHGWKEG

SPIN1

51

Q9Y657
RGNIVGCRIQHGWKD

SPIN3

46

Q5JUX0
NHVTGKCTRCNAGWI

SCARF2

341

Q96GP6
AGVVSWGDGCAQRNK

ST14

821

Q9Y5Y6
SCEQKAEGHGSGSWQ

RAET1G

126

Q6H3X3
GTTILAKHAWCGGNF

VAMP7

11

P51809
VVCNGQLQGVVSWGH

PRSS3

261

P35030
CGKAFLWGSQLTRHQ

ZNF790

511

Q6PG37
CGRGFTWKSNLITHQ

ZNF875

306

P10072
VLNKQGHGCESDIWA

PLK2

251

Q9NYY3
SWLGNCLHANAGRTK

UBE4A

401

Q14139
TNSIHWCGISGRQLG

TRAPPC13

346

A5PLN9
GSGRACSTVEGKWQQ

UIMC1

596

Q96RL1
RCKAWNVHGAQSGSV

SIGLEC11

531

Q96RL6
TTGEELCNGHGLWVK

HECTD3

106

Q5T447
LNKGGWDHGDTQSIQ

KIAA1522

81

Q9P206