Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnuclear receptor activity

NR6A1 RARG RXRA RXRB ESR2

1.05e-0860255GO:0004879
GeneOntologyMolecularFunctionligand-activated transcription factor activity

NR6A1 RARG RXRA RXRB ESR2

1.14e-0861255GO:0098531
GeneOntologyMolecularFunctionnuclear steroid receptor activity

RXRA RXRB ESR2

3.92e-0625253GO:0003707
GeneOntologyMolecularFunctionretinoic acid-responsive element binding

RXRA RXRB

3.15e-057252GO:0044323
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

RARG RXRA RXRB

4.36e-0555253GO:0042974
GeneOntologyMolecularFunctionestrogen response element binding

NR6A1 ESR2

8.22e-0511252GO:0034056
GeneOntologyMolecularFunctionRNA polymerase II intronic transcription regulatory region sequence-specific DNA binding

RXRA SMYD3

1.16e-0413252GO:0001162
GeneOntologyMolecularFunctionCCR6 chemokine receptor binding

DEFB114 DEFB103A

1.16e-0413252GO:0031731
GeneOntologyMolecularFunctionintronic transcription regulatory region sequence-specific DNA binding

RXRA SMYD3

2.02e-0417252GO:0001161
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF534 NR6A1 RARG ZNF556 RXRA RXRB ZNF451 ESR2

2.23e-041412258GO:0000981
GeneOntologyMolecularFunctionnuclear vitamin D receptor binding

RXRA RXRB

2.27e-0418252GO:0042809
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF534 NR6A1 RARG ZNF556 RXRA RXRB SMYD3 ESR2

2.80e-041459258GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF534 NR6A1 RARG RXRA RXRB SMYD3 ESR2

6.37e-041244257GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF534 NR6A1 RARG RXRA RXRB SMYD3 ESR2

7.24e-041271257GO:0000987
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

RXRA RXRB

8.24e-0434252GO:0046966
GeneOntologyMolecularFunctionnuclear receptor binding

RARG RXRA RXRB

1.60e-03187253GO:0016922
GeneOntologyMolecularFunctionchemoattractant activity

DEFB114 DEFB103A

2.07e-0354252GO:0042056
GeneOntologyMolecularFunctioncalcium ion binding

LRP1 SYT5 FBN2 VWCE VWA2

2.08e-03749255GO:0005509
GeneOntologyMolecularFunctionCCR chemokine receptor binding

DEFB114 DEFB103A

2.22e-0356252GO:0048020
GeneOntologyMolecularFunctionclathrin binding

LRP1 SYT5

2.80e-0363252GO:0030276
GeneOntologyMolecularFunctioncoreceptor activity

LRP1 RGMB

3.65e-0372252GO:0015026
GeneOntologyMolecularFunctionzinc ion binding

NR6A1 RARG RXRA RXRB ESR2

4.41e-03891255GO:0008270
GeneOntologyMolecularFunctionchemokine receptor binding

DEFB114 DEFB103A

4.59e-0381252GO:0042379
GeneOntologyMolecularFunctionsignaling receptor regulator activity

FBN2 DEFB114 DEFB103A ESR2

6.77e-03616254GO:0030545
GeneOntologyBiologicalProcessprostate gland epithelium morphogenesis

RARG RXRA ESR2

8.38e-0633253GO:0060740
GeneOntologyBiologicalProcessprostate gland morphogenesis

RARG RXRA ESR2

9.18e-0634253GO:0060512
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

RARG RXRA RXRB

1.29e-0538253GO:0048384
GeneOntologyBiologicalProcesspositive regulation of vitamin D receptor signaling pathway

RXRA RXRB

2.11e-056252GO:0070564
GeneOntologyBiologicalProcesspositive regulation of bone mineralization

FBN2 RXRA RXRB

2.79e-0549253GO:0030501
GeneOntologyBiologicalProcesscellular response to oxygen-containing compound

ERCC6L2 LRP1 RARG VWA2 DEFB114 RXRA RXRB SMYD3 ESR2

2.98e-051450259GO:1901701
GeneOntologyBiologicalProcesspositive regulation of biomineral tissue development

FBN2 RXRA RXRB

5.14e-0560253GO:0070169
GeneOntologyBiologicalProcessprostate gland development

RARG RXRA ESR2

5.67e-0562253GO:0030850
GeneOntologyBiologicalProcessregulation of vitamin D receptor signaling pathway

RXRA RXRB

6.31e-0510252GO:0070562
GeneOntologyBiologicalProcesspositive regulation of ossification

FBN2 RXRA RXRB

6.84e-0566253GO:0045778
GeneOntologyBiologicalProcessregulation of myelination

RARG RXRA RXRB

7.16e-0567253GO:0031641
GeneOntologyBiologicalProcessvitamin D receptor signaling pathway

RXRA RXRB

9.24e-0512252GO:0070561
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

RARG RXRA RXRB ESR2

9.61e-05202254GO:0141193
GeneOntologyBiologicalProcesspositive chemotaxis

LRP1 DEFB114 DEFB103A

1.00e-0475253GO:0050918
GeneOntologyBiologicalProcessurogenital system development

RARG RXRA ESR2

1.17e-0479253GO:0001655
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

NR6A1 RARG RXRA RXRB ESR2

1.24e-04416255GO:0030522
GeneOntologyBiologicalProcessepithelial cell differentiation involved in prostate gland development

RXRA ESR2

1.47e-0415252GO:0060742
GeneOntologyBiologicalProcessregulation of bone mineralization

FBN2 RXRA RXRB

1.78e-0491253GO:0030500
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

RXRA RXRB SMYD3 ESR2

1.84e-04239254GO:0071383
GeneOntologyBiologicalProcesscellular response to hormone stimulus

RARG VWA2 RXRA RXRB SMYD3 ESR2

1.87e-04727256GO:0032870
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

RARG RXRA RXRB ESR2

1.99e-04244254GO:0009755
GeneOntologyBiologicalProcesscellular response to lipid

RARG DEFB114 RXRA RXRB SMYD3 ESR2

2.19e-04748256GO:0071396
GeneOntologyBiologicalProcessventricular cardiac muscle cell differentiation

RXRA RXRB

2.38e-0419252GO:0055012
GeneOntologyBiologicalProcessstriated muscle cell proliferation

RXRA RXRB EPHB1

3.12e-04110253GO:0014855
GeneOntologyBiologicalProcessregulation of biomineral tissue development

FBN2 RXRA RXRB

3.46e-04114253GO:0070167
GeneOntologyBiologicalProcesscellular response to vitamin D

RXRA RXRB

3.51e-0423252GO:0071305
GeneOntologyBiologicalProcessdefense response to Gram-negative bacterium

DEFB115 DEFB114 DEFB103A

3.93e-04119253GO:0050829
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

LRP1 RGMB FBN2 VWA2 ZNF451 ESR2 EPHB1

3.93e-041186257GO:0007167
GeneOntologyBiologicalProcesspositive regulation of cholesterol efflux

LRP1 RXRA

4.86e-0427252GO:0010875
GeneOntologyBiologicalProcessresponse to retinoic acid

RARG RXRA RXRB

5.20e-04131253GO:0032526
GeneOntologyBiologicalProcessnegative regulation of transforming growth factor beta receptor signaling pathway

LRP1 FBN2 ZNF451

6.05e-04138253GO:0030512
GeneOntologyBiologicalProcessmuscle cell proliferation

RXRA RXRB ESR2 EPHB1

6.17e-04329254GO:0033002
GeneOntologyBiologicalProcesscellular response to vitamin

RXRA RXRB

6.42e-0431252GO:0071295
GeneOntologyBiologicalProcessregulation of ossification

FBN2 RXRA RXRB

7.27e-04147253GO:0030278
GeneOntologyBiologicalProcessbone mineralization

FBN2 RXRA RXRB

7.56e-04149253GO:0030282
GeneOntologyBiologicalProcessregulation of nervous system development

LRP1 RARG RXRA RXRB EPHB1

8.07e-04625255GO:0051960
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

RXRA RXRB ESR2

8.48e-04155253GO:0043401
GeneOntologyBiologicalProcessresponse to vitamin D

RXRA RXRB

9.65e-0438252GO:0033280
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

ZNF462 NR6A1 RARG RXRA RXRB SMYD3 ESR2

1.02e-031390257GO:0045944
GeneOntologyBiologicalProcessresponse to steroid hormone

RXRA RXRB SMYD3 ESR2

1.07e-03381254GO:0048545
GeneOntologyBiologicalProcesspositive regulation of sterol transport

LRP1 RXRA

1.07e-0340252GO:0032373
GeneOntologyBiologicalProcesspositive regulation of cholesterol transport

LRP1 RXRA

1.07e-0340252GO:0032376
GeneOntologyBiologicalProcessgland morphogenesis

RARG RXRA ESR2

1.26e-03178253GO:0022612
GeneOntologyBiologicalProcessresponse to hormone

RARG VWA2 RXRA RXRB SMYD3 ESR2

1.27e-031042256GO:0009725
GeneOntologyBiologicalProcessmaternal placenta development

RXRA RXRB

1.29e-0344252GO:0001893
GeneOntologyBiologicalProcessregulation of response to nutrient levels

RXRA RXRB

1.41e-0346252GO:0032107
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

LRP1 FBN2 ZNF451

1.57e-03192253GO:0017015
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

LRP1 FBN2 ZNF451

1.64e-03195253GO:1903844
GeneOntologyBiologicalProcessplacenta development

FBN2 RXRA RXRB

1.69e-03197253GO:0001890
GeneOntologyBiologicalProcessmRNA transcription by RNA polymerase II

RXRA RXRB

1.80e-0352252GO:0042789
GeneOntologyBiologicalProcessbiomineral tissue development

FBN2 RXRA RXRB

1.84e-03203253GO:0031214
GeneOntologyBiologicalProcessresponse to lipid

RARG DEFB114 RXRA RXRB SMYD3 ESR2

1.89e-031126256GO:0033993
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

LRP1 RGMB FBN2 ZNF451

1.89e-03445254GO:0141091
GeneOntologyBiologicalProcessmyelination

RARG RXRA RXRB

1.92e-03206253GO:0042552
GeneOntologyBiologicalProcessensheathment of neurons

RARG RXRA RXRB

2.00e-03209253GO:0007272
GeneOntologyBiologicalProcessaxon ensheathment

RARG RXRA RXRB

2.00e-03209253GO:0008366
GeneOntologyBiologicalProcesscellular response to nutrient

RXRA RXRB

2.01e-0355252GO:0031670
GeneOntologyBiologicalProcessregulation of cholesterol efflux

LRP1 RXRA

2.09e-0356252GO:0010874
GeneOntologyBiologicalProcessmRNA transcription

RXRA RXRB

2.16e-0357252GO:0009299
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP1 FBN2 ZNF451

2.26e-03218253GO:0090101
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

LRP1 RGMB FBN2 ZNF451

2.52e-03482254GO:0007178
GeneOntologyBiologicalProcesschemotaxis

LRP1 DEFB114 DEFB103A EPHB1

3.25e-03517254GO:0006935
GeneOntologyBiologicalProcessmuscle structure development

RXRA RXRB SMYD3 USP19 EPHB1

3.27e-03858255GO:0061061
GeneOntologyBiologicalProcessfemale pregnancy

FBN2 RXRA RXRB

3.29e-03249253GO:0007565
GeneOntologyBiologicalProcesstaxis

LRP1 DEFB114 DEFB103A EPHB1

3.29e-03519254GO:0042330
GeneOntologyBiologicalProcessmaternal process involved in female pregnancy

RXRA RXRB

3.52e-0373252GO:0060135
GeneOntologyBiologicalProcesscellular response to retinoic acid

RARG RXRB

3.52e-0373252GO:0071300
GeneOntologyBiologicalProcessorgan growth

RARG RXRA RXRB

3.55e-03256253GO:0035265
GeneOntologyBiologicalProcesscholesterol efflux

LRP1 RXRA

3.90e-0377252GO:0033344
GeneOntologyBiologicalProcessmuscle tissue development

RXRA RXRB USP19 EPHB1

4.27e-03558254GO:0060537
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

LRP1 FBN2 ZNF451

4.38e-03276253GO:0007179
GeneOntologyBiologicalProcesscardiac muscle cell proliferation

RXRA RXRB

4.41e-0382252GO:0060038
GeneOntologyBiologicalProcesscoronary vasculature development

LRP1 RXRA

4.52e-0383252GO:0060976
GeneOntologyBiologicalProcessregulation of cholesterol transport

LRP1 RXRA

4.52e-0383252GO:0032374
GeneOntologyBiologicalProcessregulation of sterol transport

LRP1 RXRA

4.52e-0383252GO:0032371
Domainzf-C4

NR6A1 RARG RXRA RXRB ESR2

2.97e-0946245PF00105
DomainNUCLEAR_REC_DBD_1

NR6A1 RARG RXRA RXRB ESR2

2.97e-0946245PS00031
DomainZnf_hrmn_rcpt

NR6A1 RARG RXRA RXRB ESR2

2.97e-0946245IPR001628
DomainNuclear_hrmn_rcpt

NR6A1 RARG RXRA RXRB ESR2

2.97e-0946245IPR001723
DomainZnF_C4

NR6A1 RARG RXRA RXRB ESR2

2.97e-0946245SM00399
DomainNUCLEAR_REC_DBD_2

NR6A1 RARG RXRA RXRB ESR2

2.97e-0946245PS51030
Domain-

NR6A1 RARG RXRA RXRB ESR2

3.32e-09472451.10.565.10
DomainHOLI

NR6A1 RARG RXRA RXRB ESR2

3.71e-0948245SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR6A1 RARG RXRA RXRB ESR2

3.71e-0948245IPR000536
DomainHormone_recep

NR6A1 RARG RXRA RXRB ESR2

3.71e-0948245PF00104
Domain-

NR6A1 RARG RXRA RXRB ESR2

9.00e-09572453.30.50.10
DomainZnf_NHR/GATA

NR6A1 RARG RXRA RXRB ESR2

9.84e-0958245IPR013088
DomainEGF_CA

LRP1 FBN2 VWCE VWA2

1.66e-05122244SM00179
DomainEGF-like_CS

LRP1 FBN2 VWCE VWA2 EPHB1

1.75e-05261245IPR013032
DomainEGF-like_Ca-bd_dom

LRP1 FBN2 VWCE VWA2

1.77e-05124244IPR001881
DomainEGF_2

LRP1 FBN2 VWCE VWA2 EPHB1

1.89e-05265245PS01186
DomainGrowth_fac_rcpt_

LRP1 FBN2 VWCE EPHB1

4.37e-05156244IPR009030
DomainRetinoid-X_rcpt/HNF4

RXRA RXRB

7.08e-0510242IPR000003
DomainDefensin_beta

DEFB114 DEFB103A

1.04e-0412242PF00711
DomainDefensin_beta-typ

DEFB114 DEFB103A

1.04e-0412242IPR001855
DomainVitD_rcpt

NR6A1 ESR2

1.43e-0414242IPR000324
DomainEGF_CA

LRP1 FBN2 VWCE

1.78e-0486243PF07645
DomainEGF_3

LRP1 FBN2 VWCE VWA2

2.13e-04235244PS50026
DomainEGF

LRP1 FBN2 VWCE VWA2

2.13e-04235244SM00181
DomainEGF_Ca-bd_CS

LRP1 FBN2 VWCE

2.54e-0497243IPR018097
DomainEGF-like_dom

LRP1 FBN2 VWCE VWA2

2.66e-04249244IPR000742
DomainEGF_CA

LRP1 FBN2 VWCE

2.70e-0499243PS01187
DomainASX_HYDROXYL

LRP1 FBN2 VWCE

2.78e-04100243PS00010
DomainEGF_1

LRP1 FBN2 VWCE VWA2

2.91e-04255244PS00022
Domainzf-MYND

SMYD3 USP19

3.27e-0421242PF01753
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 FBN2 VWCE

3.30e-04106243IPR000152
DomainZnf_MYND

SMYD3 USP19

3.60e-0422242IPR002893
DomainZF_MYND_1

SMYD3 USP19

3.60e-0422242PS01360
DomainZF_MYND_2

SMYD3 USP19

3.60e-0422242PS50865
DomaincEGF

LRP1 FBN2

5.05e-0426242IPR026823
DomaincEGF

LRP1 FBN2

5.05e-0426242PF12662
Domainzf-C2H2

ZNF462 ZNF200 ZNF534 ZNF556 ZNF451

1.64e-03693245PF00096
DomainZINC_FINGER_C2H2_2

ZNF462 ZNF200 ZNF534 ZNF556 ZNF451

2.67e-03775245PS50157
DomainZINC_FINGER_C2H2_1

ZNF462 ZNF200 ZNF534 ZNF556 ZNF451

2.70e-03777245PS00028
DomainZnf_C2H2-like

ZNF462 ZNF200 ZNF534 ZNF556 ZNF451

3.00e-03796245IPR015880
DomainZnf_C2H2

ZNF462 ZNF200 ZNF534 ZNF556 ZNF451

3.15e-03805245IPR007087
DomainZnF_C2H2

ZNF462 ZNF200 ZNF534 ZNF556 ZNF451

3.20e-03808245SM00355
Domain-

ZNF462 ZNF200 ZNF534 ZNF556

1.03e-026792443.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF462 ZNF200 ZNF534 ZNF556

1.11e-02694244IPR013087
DomainEGF

LRP1 VWA2

1.13e-02126242PF00008
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR6A1 RARG RXRA RXRB ESR2

5.51e-0948205MM14987
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR6A1 RARG RXRA RXRB ESR2

9.20e-0953205M8276
PathwayWP_VITAMIN_A1_AND_A5X_PATHWAYS

RARG RXRA RXRB

4.87e-086203M48097
PathwayWP_NUCLEAR_RECEPTORS

RARG RXRA RXRB ESR2

2.11e-0738204MM15865
PathwayWP_NUCLEAR_RECEPTORS

RARG RXRA RXRB ESR2

2.11e-0738204M39657
PathwayPID_RXR_VDR_PATHWAY

RARG RXRA RXRB

6.22e-0626203M162
PathwayPID_RETINOIC_ACID_PATHWAY

RARG RXRA RXRB

9.68e-0630203M207
PathwayKEGG_MEDICUS_VARIANT_PAX8_PPARG_FUSION_TO_PPARG_MEDIATED_TRANSCRIPTION

RXRA RXRB

1.91e-055202M49023
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_GLUCONEOGENESIS

RXRA RXRB

1.91e-055202M29812
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_LIMIT_CHOLESTEROL_UPTAKE

RXRA RXRB

1.91e-055202M29791
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_TRIGLYCERIDE_LIPOLYSIS_IN_ADIPOSE

RXRA RXRB

1.91e-055202M29792
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS

RXRA RXRB

2.86e-056202MM15663
PathwayREACTOME_BETA_DEFENSINS

DEFB115 DEFB114 DEFB103A

2.91e-0543203M565
PathwayWP_VITAMIN_A_AND_CAROTENOID_METABOLISM

RARG RXRA RXRB

2.91e-0543203M39554
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

RARG RXRA RXRB

2.91e-0543203M27443
PathwayWP_RETINOL_METABOLISM

RARG RXRA RXRB

3.12e-0544203MM15851
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

RARG RXRA RXRB

4.32e-0549203MM15186
PathwayREACTOME_DEFENSINS

DEFB115 DEFB114 DEFB103A

5.47e-0553203M557
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS

RXRA RXRB

6.84e-059202M29809
PathwayKEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY

RXRA RXRB

6.84e-059202M47629
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS

RXRA RXRB

6.84e-059202M29789
PathwayWP_VITAMIN_D_METABOLISM

RXRA RXRB

8.55e-0510202M39352
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

RARG RXRA RXRB ESR2

1.33e-04191204MM15586
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

RXRA RXRB

1.48e-0413202MM15622
PathwayREACTOME_ANTIMICROBIAL_PEPTIDES

DEFB115 DEFB114 DEFB103A

3.41e-0498203M27627
PathwayREACTOME_BETA_DEFENSINS

DEFB115 DEFB103A

3.58e-0420202MM14567
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

RARG RXRA RXRB ESR2

7.08e-04296204M27869
PathwayKEGG_THYROID_CANCER

RXRA RXRB

7.59e-0429202M523
PathwayREACTOME_DEFENSINS

DEFB115 DEFB103A

8.68e-0431202MM14568
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

RXRA RXRB

1.24e-0337202M29790
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

RXRA RXRB

1.91e-0346202M239
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

RXRA RXRB

1.99e-0347202M29777
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF200 NR6A1 RARG ZNF556 RXRA RXRB ESR2

2.15e-031387207M734
PathwayPID_AR_TF_PATHWAY

RXRA RXRB

2.52e-0353202M151
PathwayKEGG_NON_SMALL_CELL_LUNG_CANCER

RXRA RXRB

2.62e-0354202M19818
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

NR6A1 RARG RXRA RXRB ESR2

3.70e-03768205MM14851
PathwayWP_PPAR_SIGNALING

RXRA RXRB

4.00e-0367202M39553
PathwayKEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY

RXRA RXRB

4.00e-0367202M10462
PathwayKEGG_PPAR_SIGNALING_PATHWAY

RXRA RXRB

4.24e-0369202M13088
PathwayREACTOME_ANTIMICROBIAL_PEPTIDES

DEFB115 DEFB103A

4.36e-0370202MM15332
PathwayWP_NONSMALL_CELL_LUNG_CANCER

RXRA RXRB

4.61e-0372202M39738
PathwayWP_PPAR_SIGNALING_PATHWAY

RXRA RXRB

4.73e-0373202MM15995
PathwayWP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3

RXRA RXRB

4.99e-0375202M39568
PathwayKEGG_SMALL_CELL_LUNG_CANCER

RXRA RXRB

6.22e-0384202M3228
PathwayWP_SMALL_CELL_LUNG_CANCER

RXRA RXRB

8.05e-0396202M39834
Pubmed

Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.

RARG RXRA RXRB

1.31e-0942531310259
Pubmed

Nuclear receptors in Leydig cell gene expression and function.

RARG RXRA RXRB ESR2

1.51e-092225420375256
Pubmed

Developmental expression of murine retinoid X receptor (RXR) genes.

RARG RXRA RXRB

3.28e-0952538199055
Pubmed

Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development.

RARG RXRA RXRB

3.28e-0952539053308
Pubmed

The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development.

RARG RXRA RXRB

6.55e-0962539806918
Pubmed

Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes.

RARG RXRA RXRB

6.55e-09625311328745
Pubmed

Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes.

RARG RXRA RXRB

6.55e-09625316751185
Pubmed

A genetic dissection of the retinoid signalling pathway in the mouse.

RARG RXRA RXRB

6.55e-09625310604193
Pubmed

The isolation and characterization of purified heterocomplexes of recombinant retinoic acid receptor and retinoid X receptor ligand binding domains.

RARG RXRA RXRB

6.55e-0962539153406
Pubmed

Spatial distributions of retinoic acid receptor gene transcripts in the prenatal mouse inner ear.

RARG RXRA RXRB

6.55e-0962539548551
Pubmed

Functional specificity of the two retinoic acid receptor RAR and RXR families in myogenesis.

RARG RXRA RXRB

6.55e-0962539464546
Pubmed

Effect of retinoid status on the messenger ribonucleic acid expression of nuclear retinoid receptors alpha, beta, and gamma, and retinoid X receptors alpha, beta, and gamma in the mouse testis.

RARG RXRA RXRB

6.55e-0962539075714
Pubmed

Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.

RARG RXRA RXRB

6.55e-09625320557428
Pubmed

RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells.

RARG RXRA RXRB

6.55e-0962538801169
Pubmed

A decade of molecular biology of retinoic acid receptors.

RARG RXRA RXRB

6.55e-0962538801176
Pubmed

Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors.

RARG RXRA RXRB

1.15e-08725317195188
Pubmed

Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha.

RARG RXRA RXRB

1.15e-08725311493527
Pubmed

The structure of the nuclear hormone receptors.

RXRA RXRB ESR2

1.15e-08725310406480
Pubmed

Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions.

RARG RXRA RXRB

1.15e-08725312360493
Pubmed

Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases.

RARG RXRA RXRB

1.15e-08725315635645
Pubmed

Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.

RARG RXRA RXRB

1.15e-0872538090775
Pubmed

Expression of nuclear retinoic acid receptors during mouse odontogenesis.

RARG RXRA RXRB

1.83e-0882537988794
Pubmed

Retinoids and adipose tissues: metabolism, cell differentiation and gene expression.

RARG RXRA RXRB

1.83e-08825310094571
Pubmed

Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells.

RARG RXRA RXRB

1.83e-08825317124491
Pubmed

A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.

NR6A1 RARG RXRA RXRB ESR2

2.08e-0811825516971476
Pubmed

Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter.

RARG RXRA RXRB

5.39e-081125329093497
Pubmed

Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization.

RARG RXRA RXRB ESR2

6.91e-085525434292881
Pubmed

Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse.

RARG RXRA RXRB

7.19e-08122539022057
Pubmed

Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.

RARG RXRA RXRB

7.19e-081225326427057
Pubmed

Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro.

RARG RXRA RXRB

1.19e-071425318561907
Pubmed

Retinoic acid induces prostatic bud formation.

RARG RXRA RXRB

1.19e-071425318393306
Pubmed

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.

RARG RXRA RXRB

1.19e-071425321923909
Pubmed

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.

RXRA RXRB ESR2

1.48e-07152539267036
Pubmed

Understanding abnormal retinoid signaling as a causative mechanism in congenital diaphragmatic hernia.

RARG RXRA RXRB

1.48e-071525319448158
Pubmed

Expression of aldehyde dehydrogenase family 1, member A3 in glycogen trophoblast cells of the murine placenta.

RARG RXRA RXRB

1.83e-071625325577283
Pubmed

External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium.

RARG RXRA RXRB

1.83e-071625311795391
Pubmed

Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning.

RARG RXRA RXRB

3.71e-072025319605690
Pubmed

Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.

RXRA RXRB

4.96e-07225233246082
Pubmed

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

RXRA RXRB

4.96e-0722527926783
Pubmed

Endogenous retinoid X receptor ligands in mouse hematopoietic cells.

RXRA RXRB

4.96e-07225229089448
Pubmed

Daidzein down-regulates ubiquitin-specific protease 19 expression through estrogen receptor β and increases skeletal muscle mass in young female mice.

ESR2 USP19

4.96e-07225228886438
Pubmed

Retinoic acid inhibition of IL-1-induced IL-6 production by human lung fibroblasts.

RARG RXRA

4.96e-0722528301142
Pubmed

Three retinoid X receptor gene polymorphisms in plaque psoriasis and psoriasis guttata.

RXRA RXRB

4.96e-07225217341859
Pubmed

Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers.

RARG RXRA

4.96e-07225210919981
Pubmed

Retinoic acid receptor/retinoid X receptor heterodimers can be activated through both subunits providing a basis for synergistic transactivation and cellular differentiation.

RARG RXRA

4.96e-0722529083083
Pubmed

Chemopreventive efficacy of raloxifene, bexarotene, and their combination on the progression of chemically induced colon adenomas to adenocarcinomas in rats.

RXRA ESR2

4.96e-07225224080207
Pubmed

Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin.

RXRA RXRB

4.96e-07225216199515
Pubmed

Retinoid-X-receptors (α/β) in melanocytes modulate innate immune responses and differentially regulate cell survival following UV irradiation.

RXRA RXRB

4.96e-07225224810760
Pubmed

Retinoid signaling is attenuated by proteasome-mediated degradation of retinoid receptors in human keratinocyte HaCaT cells.

RARG RXRA

4.96e-07225211855864
Pubmed

Limited degradation of retinoid X receptor by calpain.

RXRA RXRB

4.96e-0722528780715
Pubmed

Nuclear hormone retinoid X receptor (RXR) negatively regulates the glucose-stimulated insulin secretion of pancreatic ß-cells.

RXRA RXRB

4.96e-07225220798333
Pubmed

A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development.

RXRA RXRB

4.96e-07225219255444
Pubmed

Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity.

RXRA RXRB

4.96e-07225222316320
Pubmed

Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid.

RARG RXRA RXRB

5.01e-072225310753524
Pubmed

Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.

RARG RXRA RXRB

5.76e-072325319737349
Pubmed

Diverse Functions of Retinoic Acid in Brain Vascular Development.

RARG RXRA RXRB

1.06e-062825327445154
Pubmed

Retinoid X receptors: X-ploring their (patho)physiological functions.

RXRA RXRB

1.49e-06325215608692
Pubmed

Mouse P450RAI (CYP26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor gamma and retinoid X receptor alpha.

RARG RXRA

1.49e-0632529442090
Pubmed

Chromosomal localization of the human retinoid X receptors.

RXRA RXRB

1.49e-0632528034312
Pubmed

RAR-, not RXR, ligands inhibit cell activation and prevent apoptosis in B-lymphocytes.

RARG RXRA

1.49e-0632529491782
Pubmed

Unique response pathways are established by allosteric interactions among nuclear hormone receptors.

RXRA RXRB

1.49e-0632527758108
Pubmed

RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification.

RARG RXRB

1.49e-06325228778663
Pubmed

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

RXRA RXRB

1.49e-0632529727070
Pubmed

Cooperative formation of high-order oligomers by retinoid X receptors: an unexpected mode of DNA recognition.

RXRA RXRB

1.49e-0632527831303
Pubmed

Differential 9-cis-retinoic acid-dependent transcriptional activation by murine retinoid X receptor alpha (RXR alpha) and RXR beta. Role of cell type and RXR domains.

RXRA RXRB

1.49e-0632528631847
Pubmed

Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.

RXRA RXRB

1.49e-06325219188585
Pubmed

Retinoid receptors trigger neuritogenesis in retinal degenerations.

RXRA RXRB

1.49e-06325221940995
Pubmed

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita.

RXRA RXRB

1.49e-0632527990953
Pubmed

The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer.

RXRA RXRB

1.49e-06325211839661
Pubmed

Differential effects of UV irradiation on nuclear retinoid receptor levels in cultured keratinocytes and melanocytes.

RARG RXRA

1.49e-06325214705796
Pubmed

Retinoid receptors in gastric cancer: expression and influence on prognosis.

RARG RXRA

1.49e-06325222901127
Pubmed

Vitamin-D receptor agonist calcitriol reduces calcification in vitro through selective upregulation of SLC20A2 but not SLC20A1 or XPR1.

RXRA RXRB

1.49e-06325227184385
Pubmed

The AF-1 and AF-2 domains of RAR gamma 2 and RXR alpha cooperate for triggering the transactivation and the degradation of RAR gamma 2/RXR alpha heterodimers.

RARG RXRA

1.49e-06325212824162
Pubmed

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

RXRA RXRB

1.49e-0632521312497
Pubmed

Multifunctional enhancers regulate mouse and human vitamin D receptor gene transcription.

RXRA RXRB

1.49e-06325219897601
Pubmed

Polymorphism of genes related to insulin sensitivity and the risk of biliary tract cancer and biliary stone: a population-based case-control study in Shanghai, China.

RXRA RXRB

1.49e-06325218375961
Pubmed

Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies.

RXRA RXRB

1.49e-0632527980510
Pubmed

Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.

RXRA RXRB

1.49e-06325218217139
Pubmed

Differential regulation of ligand-dependent and ligand-independent functions of the mouse retinoid X receptor beta by alternative splicing.

RXRA RXRB

1.49e-06325210049761
Pubmed

Immunohistochemical detection of the retinoid X receptors alpha, beta, and gamma in human prostate.

RXRA RXRB

1.49e-06325212514092
Pubmed

Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.

RXRA RXRB

1.49e-06325211053444
Pubmed

RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable.

RXRA RXRB

1.49e-0632528799145
Pubmed

Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal.

RARG RXRA RXRB

1.60e-063225317270348
Pubmed

Regulation of prefrontal patterning and connectivity by retinoic acid.

RARG RXRA RXRB

1.93e-063425334599305
Pubmed

Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.

RARG RXRA RXRB ESR2

2.43e-0613325415604093
Pubmed

A census of human transcription factors: function, expression and evolution.

ZNF200 NR6A1 RARG RXRA RXRB ZNF451 ESR2

2.57e-0690825719274049
Pubmed

The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression.

RXRA RXRB

2.97e-06425210594021
Pubmed

Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.

RXRA RXRB

2.97e-0642528670810
Pubmed

Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled.

RARG RXRA

2.97e-06425212093741
Pubmed

Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.

RXRA RXRB

2.97e-0642529804293
Pubmed

Sequence and characterization of a coactivator for the steroid hormone receptor superfamily.

RXRA RXRB

2.97e-0642527481822
Pubmed

Retinoic acid biosynthetic activity and retinoid receptors in the olfactory mucosa of adult mice.

RXRA RXRB

2.97e-06425210079186
Pubmed

Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand.

RXRA RXRB

2.97e-0642528524212
Pubmed

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis.

RARG RXRA

2.97e-0642527923367
Pubmed

RXRs control serous macrophage neonatal expansion and identity and contribute to ovarian cancer progression.

RXRA RXRB

2.97e-06425232246014
Pubmed

The retinoid receptors.

RXRA RXRB

2.97e-0642527967725
Pubmed

Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.

RXRA RXRB

2.97e-06425226355550
Pubmed

Retina-specific nuclear receptor: A potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Müller glial cells.

RXRA RXRB

2.97e-06425210611353
Pubmed

Effects of retinoid ligands on RIP140: molecular interaction with retinoid receptors and biological activity.

RXRA RXRB

2.97e-06425212549917
Pubmed

Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms.

RARG RXRA

2.97e-0642529376317
InteractionNCOA1 interactions

NR6A1 RARG RXRA RXRB ESR2

8.81e-07146255int:NCOA1
InteractionNR0B2 interactions

RARG RXRA RXRB ESR2

3.17e-0683254int:NR0B2
InteractionTGIF1 interactions

RXRA RXRB ESR2

1.74e-0541253int:TGIF1
InteractionNR2F6 interactions

RARG RXRA ESR2

2.47e-0546253int:NR2F6
InteractionRARB interactions

RARG RXRA RXRB

2.47e-0546253int:RARB
InteractionRARG interactions

RARG RXRA RXRB

4.97e-0558253int:RARG
CytobandEnsembl 112 genes in cytogenetic band chr6p12

DEFB114 ZNF451

2.72e-03142252chr6p12
GeneFamilyNuclear hormone receptors

NR6A1 RARG RXRA RXRB ESR2

1.34e-094919571
GeneFamilyDefensins, beta

DEFB115 DEFB114 DEFB103A

1.55e-0547193503
GeneFamilyZinc fingers MYND-type

SMYD3 USP19

2.17e-042119287
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF462 ZNF200 ZNF534 ZNF556 ZNF451

7.12e-0471819528
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_200

ERCC6L2 RGMB EPHB1

6.57e-0567253DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_100

ERCC6L2 RGMB EPHB1

1.24e-0483253gudmap_developingLowerUrinaryTract_e14.5_ bladder_100
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

NR6A1 VWCE RXRA

1.58e-0490253PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_100

ERCC6L2 RGMB

1.79e-0417252gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k4
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC81 VWA2 DEFB114

6.87e-051432536df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SYT5 RXRA

9.58e-051602530544bc465af208da448858d6e174ff56f2e08a46
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF462 ZNF556 ESR2

9.94e-05162253768a566e76923323c1f197f60bab472a8784490b
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ERCC6L2 VWCE USP19

1.07e-04166253f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell343B-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CCDC81 NR6A1 VWCE

1.13e-04169253e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC6L2 RARG SMYD3

1.27e-041762531510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 RXRA SMYD3

1.27e-04176253450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF556 ESR2 EPHB1

1.47e-04185253f4588468e8654363f48adbe427dff10f16f1c7fe
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF556 ESR2 EPHB1

1.47e-041852533cb816fc9541c04b4436e21d984216cfbbacff98
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF556 ESR2 EPHB1

1.47e-04185253c2e70405969616c28fb6379ee318e17bbcef7b49
ToppCellMild-Lymphoid-pDC|Mild / Condition, Lineage, Cell class and cell subclass

ZNF556 ESR2 EPHB1

1.50e-041862537fa82972c726025d6402e5eb7bf0db3b699eba4c
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ZNF556 ESR2 EPHB1

1.50e-04186253d2fbf53aac905c9896272ec5c2db28ee1a60f4be
ToppCellMild-Lymphoid-pDC-|Mild / Condition, Lineage, Cell class and cell subclass

ZNF556 ESR2 EPHB1

1.50e-041862531d05e73ae2ec0cc27f79e4fa40d6b21790059f80
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZNF556 ESR2 EPHB1

1.50e-0418625379aedd5aed72509a4925e9f6cb43bc0c798c86f5
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ZNF556 ESR2 EPHB1

1.50e-04186253b031f4e6867b6200b85f43276a34749bf5f4603f
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK-NK_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ZNF462 RGMB RARG

1.52e-041872533301e0fca8c436d136c71f1a8fd59b3bb11bdd83
ToppCellMild_COVID-19-Myeloid-pDC|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ZNF556 ESR2 EPHB1

1.52e-0418725399c3c4a7b9179dce7982dc6516d561c952abc80e
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 VWA2 EPHB1

1.64e-0419225381baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF462 FGD5 RARG

1.67e-0419325387d3a577d37fb0cb4b6313c596310de452bc3872
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF462 FGD5 RARG

1.67e-04193253826b8dd801298b3e0cd76232feae5a14026b8806
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 VWA2 EPHB1

1.67e-041932537261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP1 FBN2 RXRA

1.72e-04195253580ed65b4152483b642a7e7dbdf00d03588c46f6
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_monocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP1 FBN2 RXRA

1.77e-04197253b91016249b3585aa3536e96af18e4f1b1d2d5ce4
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RGMB FBN2 EPHB1

1.77e-04197253f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP1 FBN2 RXRA

1.77e-04197253ec46aa307ce5774b4c0fcba64514f2d0cab3c4f9
ToppCellmLN-(4)_Monocyte-(40)_Monocyte|mLN / shred on region, Cell_type, and subtype

LRP1 FBN2 RXRA

1.82e-04199253bcbb1eee8d79bf670dbe113094c3a292b135ce2f
ToppCellmLN-(4)_Monocyte|mLN / shred on region, Cell_type, and subtype

LRP1 FBN2 RXRA

1.82e-041992536795ff31f92580195c9db776951f99d647484d24
ToppCellmLN-Monocyte|mLN / Region, Cell class and subclass

LRP1 FBN2 RXRA

1.82e-04199253241f790cd5d8a9b2451333deecc826a673bae70a
ToppCellmLN-Monocyte-Monocyte|mLN / Region, Cell class and subclass

LRP1 FBN2 RXRA

1.82e-04199253dcee372774c169a3048bdaed3734b3215bf8ffad
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LRP1 FBN2 RXRA

1.85e-04200253107a0665fb20247511a430178effd7630a619488
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LRP1 FBN2 RXRA

1.85e-042002539e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Nnat_(Neuron.Slc17a7.Syt6-Nnat)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CCDC81 VWA2

5.49e-0462252dd2e222d454fb78fed8b37901cbf04c0080ed010
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Nnat_(Neuron.Slc17a7.Syt6-Nnat)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CCDC81 VWA2

5.49e-04622526a3f990e8d59392ad909634a239b3ab4f13d8855
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Prlr_(Entorhinal_cortex?)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

VWA2 ESR2

6.03e-046525257d0d892dab8bc8465067feeff279c967a43b781
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Prlr_(Entorhinal_cortex?)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

VWA2 ESR2

6.03e-0465252aba26f607f35c2920cdf956309285ad9e7b758a7
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Slc17a6-Inhibitory_Neuron.Slc17a6-Gad1Gad2.Asb4_(Periventricular_Fiber_System_(Pv))-|Thalamus / BrainAtlas - Mouse McCarroll V32

VWCE ESR2

1.26e-0394252be1dcfe287f58d608ccdb47cf9c1d12b5e3aa60d
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Slc17a6|Thalamus / BrainAtlas - Mouse McCarroll V32

VWCE ESR2

1.26e-0394252576c37fa53fab679f5e8786f5c798e18998186e9
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Slc17a6-Inhibitory_Neuron.Slc17a6-Gad1Gad2.Asb4_(Periventricular_Fiber_System_(Pv))|Thalamus / BrainAtlas - Mouse McCarroll V32

VWCE ESR2

1.26e-039425282e9178c848468497295c4cc59c662b9279208a1
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 EPHB1

1.50e-03103252eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ZNF462 CCDC81

1.65e-03108252ee924deacd14ea404fda80ed633960143fd474c0
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ERCC6L2 VWCE

2.10e-03122252a2f343962069253a08faa80fd70723b8488a99ec
ToppCellTCGA-Testes|World / Sample_Type by Project: Shred V9

ZNF534 NR6A1

2.31e-03128252a09b0e221b8749510002304e4d34d6a2eb8867e9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN2 ESR2

2.31e-03128252076ba9de63b9a4b5a2f7e7924b9a86e8eafce91f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN2 ESR2

2.38e-031302527d4319aae42acc914757796877b8f0d874acbec4
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-3|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

LRP1 RXRA

2.60e-031362524f5e0b6c7d6e3e922af4daa7c3eb56490455c1df
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3|Hippocampus / BrainAtlas - Mouse McCarroll V32

SYT5 SMYD3

2.68e-03138252b63e26afafbd2cdeed9c9451e6f530ab6295504c
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC81 FBN2

2.83e-03142252e160f35b3c18e77c4107fe96db5f56227c91785e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF556 EPHB1

2.83e-03142252199a0a1024b6cc446f5ca1f277846a2bdb227a9f
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|390C / Donor, Lineage, Cell class and subclass (all cells)

SYT5 ESR2

2.87e-03143252d877d914e4e74db2053baa310d318d6440e672bc
ToppCell10x5'-bone_marrow-Myeloid_Monocytic-Cycling_mono|bone_marrow / Manually curated celltypes from each tissue

LRP1 FBN2

3.07e-03148252de35eeefad0e27a0d127e2e4bedead2bddb75152
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYT5 CCDC81

3.07e-03148252d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYT5 CCDC81

3.07e-03148252c8e93b87212f55774223caa385859c566fa1981f
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYT5 CCDC81

3.19e-0315125281cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYT5 CCDC81

3.19e-031512529cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SYT5 CCDC81

3.27e-031532522482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SYT5 CCDC81

3.27e-03153252fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

LRP1 RARG

3.40e-03156252ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

ZNF556 EPHB1

3.40e-0315625219472ef1642c2ad333aa3ce3675a25c6ab1d4556
ToppCellfacs-Marrow-B-cells-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 CCDC81

3.44e-031572520966e347f8d32b13f8a3b3afba3f64637c69cdf9
ToppCellfacs-Marrow-B-cells-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 CCDC81

3.44e-031572526ebfedd91d62c6d4aa8f046657a899a279f82ba2
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC81 ZNF556

3.49e-03158252da060f5b61c7088f700d138b02ea596adacf7d60
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ZNF451

3.49e-03158252d3446fc98eff09c3626b47a2c90d07cd985378b5
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ZNF451

3.49e-03158252df614450e10629dc9115d7365397663e82f9e48f
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

CCDC81 FBN2

3.49e-03158252ab05f6d7968ccd6d3826cd71b763dbedc83822c3
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ZNF556 EPHB1

3.49e-031582522af7beb48272e5368d9ba6b80f08d47ab8556c08
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF462 FBN2

3.49e-031582526d2709b387945c015faa223c20d22b52a4082140
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 ESR2

3.53e-031592524000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 ESR2

3.53e-031592527619d0d49738dd08daf01b42664691a5323aa793
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-tDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ZNF556 EPHB1

3.53e-03159252141c3ed35c7d11fcaec4acd9cb37104cc259db25
ToppCelldroplet-Marrow-BM-30m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 RARG

3.57e-03160252822adcf5f9208f305cafffd8ed97f3a061e82b03
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FGD5 FBN2

3.62e-03161252b8c74ca839ce95ce97e3535086272f60a5135c52
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NR6A1 EPHB1

3.62e-0316125278cc5bc488bc47726195a649946d414e6bfabf94
ToppCellBAL-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

RARG EPHB1

3.62e-031612527a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCellnormal-na-Lymphocytic_B-B_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ZNF534 CCDC81

3.66e-03162252ae292318d339305932457bb0e91430594f7a3dfa
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN2 NR6A1

3.66e-0316225234b4cd3d2258f88dfbd6d32abd1db87aff8a6b6f
ToppCelldroplet-Marrow-BM-30m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 RARG

3.66e-0316225276e289ad9fd3694f77fd0d19e74c1cb8e87b8094
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NR6A1 EPHB1

3.66e-031622520fa93efc9c005d1e649b3f7069ae8641d6e41ed8
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF451 ESR2

3.71e-031632523087224d3f16f5d3aecc3e1e4366220231afe31f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 ZNF556

3.71e-03163252551b3788bcf494c6121e64ce5af72266de12a06b
ToppCell390C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF534 NR6A1

3.75e-031642522957065d7f1332c5280d47be7cc342286f84be3e
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

FGD5 VWA2

3.75e-031642524d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCell343B-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CCDC81 NR6A1

3.75e-03164252eae6d440877b292ad18dc4bd02802dda5b2f9c60
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FGD5 FBN2

3.75e-03164252ed7e0c8ccad7d19b9cc72d70391936ff5e698f28
ToppCellURO-Lymphocyte-T_NK-MAIT|URO / Disease, Lineage and Cell Type

RARG ESR2

3.75e-03164252cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCell390C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF534 NR6A1

3.75e-0316425282e57d618c6e59bca4a03d31caf35b6043dfcf52
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZNF462 CCDC81

3.84e-031662528d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN2 ESR2

3.84e-031662525e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN2 ESR2

3.84e-03166252bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell10x5'-Liver-Hematopoietic_progenitors|Liver / Manually curated celltypes from each tissue

FBN2 RXRA

3.84e-03166252ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Liver / Manually curated celltypes from each tissue

FBN2 RXRA

3.84e-03166252a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FGD5 ZNF556

3.84e-03166252c8fd241088de27c6e741a5dfee3cd770183b6bcb
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RXRA EPHB1

3.88e-0316725226cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYT5 EPHB1

3.88e-031672525accd0bc7c95089feb2c09376d12cd8bd3773775
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

SYT5 CCDC81

3.88e-03167252442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RXRA EPHB1

3.88e-03167252b93103a868fba63a8910bffb690a6242b9252833
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF200 CCDC81

3.88e-03167252b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF462 RXRA

3.88e-0316725299db8871c62336bd215efb65e969783d2b6003b0
ToppCell368C-Myeloid-Dendritic-pDC|368C / Donor, Lineage, Cell class and subclass (all cells)

SYT5 EPHB1

3.88e-031672521e2fc1637769405a61f4c7e44945712a1888a299
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SMYD3 ESR2

3.88e-03167252a813b95c2fafb638b249bc4fa4f708c6f39ad444
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF200 CCDC81

3.88e-0316725294fc7df7ca55cd722a8dbd153201a29891217473
DrugAlitretinoin

RARG RXRA RXRB

2.33e-086253DB00523
DrugAdapalene

RARG RXRA RXRB

2.33e-086253DB00210
DrugEtretinate

RARG RXRA RXRB

2.33e-086253DB00926
DrugAcitretin

RARG RXRA RXRB

4.08e-087253DB00459
DrugAGN 191659

RARG RXRA RXRB

4.08e-087253CID006366726
DrugAGN 190121

RARG RXRA RXRB

4.08e-087253CID006441236
DrugHX 600

RARG RXRA RXRB

6.52e-088253ctd:C104181
DrugTTNN

RARG RXRA RXRB

6.52e-088253CID000135754
DrugAGN 191701

RARG RXRA RXRB

1.92e-0711253CID006438168
DrugUVI 3003

RARG RXRA RXRB

1.92e-0711253ctd:C525131
Drugdi-n-propylphthalate

RXRA RXRB ESR2

2.56e-0712253ctd:C106479
Drugtazarotenic acid

RARG RXRA RXRB

3.32e-0713253CID000147525
DrugCd2665

RARG RXRA RXRB

3.32e-0713253CID000216241
DrugAC1L1DMQ

RARG RXRA RXRB

4.22e-0714253CID000002418
Drugphthalic acid

RXRA RXRB ESR2

7.87e-0717253ctd:C032279
DrugHX600

RARG RXRA RXRB

9.44e-0718253CID000128016
Drugdiheptyl phthalate

RXRA RXRB ESR2

1.54e-0621253ctd:C089799
Drugdi-n-hexyl phthalate

RXRA RXRB ESR2

1.78e-0622253ctd:C027387
Drugadapalene

RARG RXRA RXRB

1.78e-0622253CID000060164
DrugT0901317

LRP1 RARG RXRA RXRB

1.78e-0681254CID000447912
DrugZoxazolamine [61-80-3]; Up 200; 23.8uM; PC3; HT_HG-U133A

LRP1 RARG ZNF556 USP19 EPHB1

2.18e-061982556290_UP
DrugAC1L2X6Z

RARG RXRA RXRB

3.36e-0627253CID000130325
DrugBexarotene

RXRA RXRB

3.47e-063252DB00307
Drug2-hydroxyphytanic acid

RXRA RXRB

3.47e-063252ctd:C002585
DrugAC1O5SBP

RXRA RXRB

3.47e-063252CID006439746
DrugAGN 193109

RARG RXRA RXRB

5.15e-0631253CID000177238
Drugrosavin

FBN2 RXRA ESR2

5.68e-0632253ctd:C529148
DrugCD367

RARG RXRA RXRB

6.24e-0633253CID000119342
DrugTazarotene

RARG RXRB

6.94e-064252DB00799
DrugAGN 190727

RXRA RXRB

6.94e-064252CID006439768
DrugDR-0

NR6A1 RXRA RXRB

7.48e-0635253CID010062716
Drug2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene

RXRA RXRB ESR2

8.15e-0636253ctd:C054919
DrugRo 41-5253

RARG RXRA RXRB

8.87e-0637253CID005312120
Drugtazarotene

RARG RXRA RXRB

1.12e-0540253CID000005381
Drug7-methoxycitronellal

RXRA RXRB

1.16e-055252CID000019223
Drug13,14-dihydroretinol

RXRA RXRB

1.16e-055252CID000446798
Drug7-methoxycitronellic acid

RXRA RXRB

1.16e-055252CID000171516
Drug2-tert-butylphenol

RXRB ESR2

1.16e-055252ctd:C035406
Drugacyclic retinoid

RARG RXRA RXRB

1.21e-0541253CID006437836
DrugEtretinate-d3

RARG RXRA RXRB

1.61e-0545253CID000003312
DrugMethoprene

RXRA RXRB

1.73e-056252ctd:D008726
Drugtriphenyltin hydroxide

RXRA RXRB

1.73e-056252ctd:C007567
Drugdiethyl phthalate

RXRA RXRB ESR2

1.96e-0548253ctd:C007379
Drugdi-n-pentyl phthalate

RXRA RXRB ESR2

2.35e-0551253ctd:C034171
DrugTretinoin

RARG RXRB

3.23e-058252DB00755
DrugAC1O5JP6

RXRA RXRB

3.23e-058252CID006435379
DrugRifampin

ZNF462 ZNF534 RXRA ZNF451 ESR2

3.73e-05356255ctd:D012293
DrugPropolis

FBN2 RXRA ESR2

3.84e-0560253ctd:D011429
Drug3,5-di-tert-butylchalcone 4'-carboxylic acid

RARG RXRA

5.18e-0510252ctd:C054189
DrugHX 630

RXRA RXRB

5.18e-0510252ctd:C422175
Drugdiazepinylbenzoic acid

RXRA RXRB

5.18e-0510252ctd:C438269
Drugretinamide

RARG RXRA RXRB

5.84e-0569253CID005370221
DrugMusk T

RXRA RXRB

6.33e-0511252CID000061014
Drug9-cis-acitretin

RARG RXRA RXRB

6.36e-0571253CID000041317
Drugsodium cholate

LRP1 RARG RXRA RXRB ESR2

7.13e-05408255CID000000303
DrugNSC46155

RXRA RXRB

7.59e-0512252CID000457869
DrugAC1L1KPQ

RARG RXRA RXRB

8.43e-0578253CID000005602
DrugGW2331

RXRA RXRB

8.96e-0513252CID000657048
DrugA-74702

RARG RXRA RXRB

9.09e-0580253CID000452307
DrugAC1L9M5J

NR6A1 RARG RXRA RXRB

9.31e-05221254CID000448615
Drugbenzoate

RARG RXRA RXRB ESR2

9.31e-05221254CID000000242
DrugSulfonamides

RXRA RXRB

1.04e-0414252ctd:D013449
Drug2,4-dichlorophenol

RXRB ESR2

1.04e-0414252ctd:C004762
DrugAC1L9K70

RARG RXRA RXRB ESR2

1.05e-04228254CID000446871
Drug5 alpha-androstane

RXRA RXRB ESR2

1.05e-0484253CID000094144
Drugtamibarotene

RARG RXRA RXRB

1.13e-0486253CID000108143
Drugeq N

RARG RXRA RXRB

1.47e-0494253CID000002126
DrugRodeo

ZNF451 EPHB1

1.56e-0417252CID000038078
DrugAC1L1GHE

FBN2 NR6A1 ESR2

1.56e-0496253CID000003684
Drugandrost-2-en-3-ol

RXRA RXRB

1.75e-0418252CID000166036
DrugAC1L1JLU

RARG RXRA RXRB

1.98e-04104253CID000005098
Drugbutylbenzyl phthalate

RXRA RXRB ESR2

2.21e-04108253ctd:C027561
DrugE-guggulsterone

RXRA RXRB ESR2

2.21e-04108253CID006439929
Drugvitamin D3

LRP1 RARG RXRA RXRB

2.22e-04277254CID000002735
Drugbexarotene

RARG RXRA RXRB

2.40e-04111253CID000082146
DrugTeniposide

RXRA ESR2

2.40e-0421252ctd:D013713
DrugRo 15-0778

RXRA RXRB

2.89e-0423252CID006436116
Drugalitretinoin

RARG RXRA RXRB ESR2

3.04e-04301254ctd:C103303
DrugAC1L2E0P

RARG RXRA RXRB ESR2

3.28e-04307254CID000019390
Drugscoparone

RXRA RXRB

3.42e-0425252CID000008417
DrugPrt-H

RXRA RXRB

3.70e-0426252CID003050291
Drugsodium silicate

NR6A1 ESR2

4.30e-0428252CID000023266
DrugSR-12813

RXRA RXRB

4.61e-0429252CID000446313
Drugfludioxonil

RXRB ESR2

4.94e-0430252ctd:C108339
DrugRo 41-5253

RARG RXRA

4.94e-0430252ctd:C084904
DrugT0070907

RXRA RXRB

5.28e-0431252CID002777391
DrugEndrin

RARG ESR2

5.63e-0432252ctd:D004732
DrugAC1L3LFV

RXRA RXRB

5.99e-0433252CID000091134
DrugRetinoids

RXRA RXRB

6.36e-0434252ctd:D012176
Drugandrostan-3-ol

RXRA RXRB ESR2

6.99e-04160253CID000092877
Drugosajin

RXRA ESR2

7.13e-0436252ctd:C485800
DrugDiosgenin

RXRA ESR2

7.13e-0436252ctd:D004144
Drugciglitazone

RARG RXRA RXRB

8.19e-04169253CID000002750
Drugvitamin D3 analog

RXRA RXRB

9.25e-0441252CID006438384
DrugD-triiodothyronine

RARG RXRA RXRB ESR2

9.63e-04409254CID000000861
Diseaseprostate carcinoma in situ (biomarker_via_orthology)

LRP1 RXRA

2.89e-064212DOID:8634 (biomarker_via_orthology)
Diseasemigraine disorder

LRP1 ZNF462 FBN2 SMYD3

1.07e-04357214MONDO_0005277
Diseasebirth weight, pelvic organ prolapse

FBN2 RXRA

5.56e-0449212EFO_0004344, EFO_0004710
DiseaseColorectal Carcinoma

LRP1 FBN2 VWA2 ESR2

1.38e-03702214C0009402
Diseasemigraine disorder, Headache

LRP1 ZNF462

1.70e-0386212HP_0002315, MONDO_0005277
Diseasediffuse plaque measurement

CCDC81 FBN2 RXRA SMYD3

1.82e-03758214EFO_0010699
Diseaselifestyle measurement, depressive symptom measurement

RGMB SMYD3

2.52e-03105212EFO_0007006, EFO_0010724
Diseaselarge artery stroke

LRP1 FGD5

2.91e-03113212EFO_0005524
DiseaseBeta blocking agent use measurement

FGD5 FBN2

2.96e-03114212EFO_0009929
Diseaseprostate cancer (is_implicated_in)

ESR2 EPHB1

3.12e-03117212DOID:10283 (is_implicated_in)
DiseaseAlzheimer's disease (is_implicated_in)

LRP1 ESR2

3.94e-03132212DOID:10652 (is_implicated_in)
Diseaseascending aortic diameter

FGD5 FBN2

4.42e-03140212EFO_0021787
Diseasemean arterial pressure

FGD5 FBN2 RXRA

5.10e-03499213EFO_0006340
Diseasehematocrit

ZNF462 FGD5 RXRA ESR2

5.15e-031011214EFO_0004348
DiseaseParoxysmal atrial fibrillation

ZNF462 ESR2

5.46e-03156212C0235480
DiseasePersistent atrial fibrillation

ZNF462 ESR2

5.46e-03156212C2585653
Diseasefamilial atrial fibrillation

ZNF462 ESR2

5.46e-03156212C3468561
DiseaseAtrial Fibrillation

ZNF462 ESR2

5.73e-03160212C0004238
DiseaseMammary Neoplasms, Human

FGD5 RXRB ESR2

5.87e-03525213C1257931
DiseaseMammary Carcinoma, Human

FGD5 RXRB ESR2

5.87e-03525213C4704874
DiseaseMammary Neoplasms

FGD5 RXRB ESR2

5.93e-03527213C1458155
Diseasecircadian rhythm

CCDC81 EPHB1

5.94e-03163212EFO_0004354
DiseaseBreast Carcinoma

FGD5 RXRB ESR2

6.28e-03538213C0678222
DiseaseMalignant neoplasm of breast

FGD5 RARG RXRB ESR2

6.37e-031074214C0006142

Protein segments in the cluster

PeptideGeneStartEntry
KVTRNRCQYCRLQKC

RARG

136

P13631
YNIICKKCRADRRSC

EPHB1

356

P54762
NRRKSCQACRLRKCY

ESR2

196

Q92731
CNSRRCKKTFRQCSN

LRP1

2561

Q07954
CKKTFRQCSNGRCVS

LRP1

2566

Q07954
ADRCTKRYGRCKRDC

DEFB114

26

Q30KQ6
ACGKIVCRNCSRNKY

FGD5

1266

Q6ZNL6
QCEKYRRCKQCQRRT

CCDC81

616

Q6ZN84
TCRSGQKRRNCCYKT

ERCC6L2

431

Q5T890
YGKCRNTIGSFKCRC

FBN2

1086

P35556
RRCYYGTGRCRKSCK

DEFB115

36

Q30KQ5
KRQRNRCQYCRYQKC

RXRA

181

P19793
QIGKCSTRGRKCCRR

DEFB103A

51

P81534
RKQRNRCQYCRLLKC

NR6A1

106

Q15406
CCFCLYRKSCRRRTG

SYT5

46

O00445
RAYAGCTQRTSKACR

RGMB

86

Q6NW40
RCSQCRVAKYCSAKC

SMYD3

61

Q9H7B4
KRQRNRCQYCRYQKC

RXRB

251

P28702
TCGCRESYICKVNRK

ZNF451

721

Q9Y4E5
KRCTRCYRVGYCNQL

USP19

806

O94966
LRKNCCTSVRRYECS

ZNF556

136

Q9HAH1
CTSVRRYECSQCGKL

ZNF556

141

Q9HAH1
SCVLQNGSYRCKCRD

VWA2

726

Q5GFL6
QQRCKNSIGSYKCSC

VWCE

191

Q96DN2
RRYKCNECGKAFRTC

ZNF534

421

Q76KX8
CKKCGRRFGRLSNCT

ZNF200

366

P98182
RCQLCKYFCSTRKGI

ZNF462

1661

Q96JM2