Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	3.76e-07	5	68	3	GO:0030156
GeneOntologyMolecularFunction	cyclosporin A binding	NKTR PPIH PPIAL4G	7.26e-05	24	68	3	GO:0016018
GeneOntologyMolecularFunction	LIM domain binding	LDB1 TLN1	4.05e-04	9	68	2	GO:0030274
GeneOntologyMolecularFunction	peptidyl-prolyl cis-trans isomerase activity	NKTR PPIH PPIAL4G	6.60e-04	50	68	3	GO:0003755
GeneOntologyMolecularFunction	cis-trans isomerase activity	NKTR PPIH PPIAL4G	7.83e-04	53	68	3	GO:0016859
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	TGFBR3 RIPK3 BRAF MAP4K1 RIOK3 MAPK7 DYRK2	7.93e-04	446	68	7	GO:0004674
GeneOntologyMolecularFunction	vinculin binding	TLN1 PXN	8.70e-04	13	68	2	GO:0017166
GeneOntologyMolecularFunction	protein kinase activity	TGFBR3 IGF2R RIPK3 BRAF MAP4K1 RIOK3 MAPK7 DYRK2	9.60e-04	600	68	8	GO:0004672
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	9.73e-05	28	67	3	GO:0002177
GeneOntologyCellularComponent	dendrite	PCSK5 DNAJB1 SLC8A2 RAP1GAP FXR2 KCNQ3 PLEC GRM6 GPR179 ITPR1	3.83e-04	858	67	10	GO:0030425
GeneOntologyCellularComponent	dendritic tree	PCSK5 DNAJB1 SLC8A2 RAP1GAP FXR2 KCNQ3 PLEC GRM6 GPR179 ITPR1	3.90e-04	860	67	10	GO:0097447
Domain	Cyclophilin-type_PPIase_CS	NKTR PPIH PPIAL4G	4.29e-05	19	68	3	IPR020892
Domain	Cyclophilin-type_PPIase	NKTR PPIH PPIAL4G	5.86e-05	21	68	3	IPR024936
Domain	Cyclophilin-like_dom	NKTR PPIH PPIAL4G	6.76e-05	22	68	3	IPR029000
Domain	CSA_PPIASE_2	NKTR PPIH PPIAL4G	6.76e-05	22	68	3	PS50072
Domain	Pro_isomerase	NKTR PPIH PPIAL4G	6.76e-05	22	68	3	PF00160
Domain	-	NKTR PPIH PPIAL4G	6.76e-05	22	68	3	2.40.100.10
Domain	Cyclophilin-type_PPIase_dom	NKTR PPIH PPIAL4G	6.76e-05	22	68	3	IPR002130
Domain	CSA_PPIASE_1	NKTR PPIH PPIAL4G	6.76e-05	22	68	3	PS00170
Domain	Rap_GAP	RAP1GAP RAP1GAP2	5.77e-04	10	68	2	PF02145
Domain	Rap_GAP_dom	RAP1GAP RAP1GAP2	7.03e-04	11	68	2	IPR000331
Domain	RAPGAP	RAP1GAP RAP1GAP2	7.03e-04	11	68	2	PS50085
Domain	FN3	RIMBP3 RIMBP3C RIMBP3B IL4R CDON	7.90e-04	199	68	5	PS50853
Domain	FN3_dom	RIMBP3 RIMBP3C RIMBP3B IL4R CDON	9.84e-04	209	68	5	IPR003961
Domain	PLAC	THSD4 PCSK5	1.16e-03	14	68	2	PF08686
Domain	PLAC	THSD4 PCSK5	2.15e-03	19	68	2	PS50900
Domain	PLAC	THSD4 PCSK5	2.15e-03	19	68	2	IPR010909
Domain	GPCR_3	GRM6 GPR179	2.62e-03	21	68	2	IPR000337
Domain	7tm_3	GRM6 GPR179	2.88e-03	22	68	2	PF00003
Domain	G_PROTEIN_RECEP_F3_2	GRM6 GPR179	2.88e-03	22	68	2	PS00980
Domain	G_PROTEIN_RECEP_F3_3	GRM6 GPR179	2.88e-03	22	68	2	PS00981
Domain	G_PROTEIN_RECEP_F3_1	GRM6 GPR179	2.88e-03	22	68	2	PS00979
Domain	G_PROTEIN_RECEP_F3_4	GRM6 GPR179	2.88e-03	22	68	2	PS50259
Domain	GPCR_3_C	GRM6 GPR179	2.88e-03	22	68	2	IPR017978
Domain	SH3_9	RIMBP3 RIMBP3C RIMBP3B	2.89e-03	78	68	3	PF14604
Domain	Actinin_actin-bd_CS	SPTB PLEC	3.15e-03	23	68	2	IPR001589
Domain	ACTININ_2	SPTB PLEC	3.15e-03	23	68	2	PS00020
Domain	ACTININ_1	SPTB PLEC	3.15e-03	23	68	2	PS00019
Domain	SH3_2	RIMBP3 RIMBP3C RIMBP3B	3.81e-03	86	68	3	IPR011511
Domain	SH3_2	RIMBP3 RIMBP3C RIMBP3B	3.81e-03	86	68	3	PF07653
Domain	FN3	RIMBP3C RIMBP3B IL4R CDON	4.63e-03	185	68	4	SM00060
Domain	Spectrin_repeat	SPTB PLEC	4.98e-03	29	68	2	IPR002017
Domain	Spectrin/alpha-actinin	SPTB PLEC	6.04e-03	32	68	2	IPR018159
Domain	SPEC	SPTB PLEC	6.04e-03	32	68	2	SM00150
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	BRAF TLN1 PXN MAPK7 ITGA9	2.94e-05	102	50	5	M39577
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	BRAF TLN1 PXN MAPK7 ITGA9	2.94e-05	102	50	5	MM15830
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	2.99e-08	4	69	3	19091768
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	MYCBP2 SUPT6H TLN1 SPTB PXN RIOK3 PLEC MED13 RABGGTB NOTCH3	5.19e-08	497	69	10	23414517
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	7.45e-08	5	69	3	17855024
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RABL6 PCSK5 SETD1A IGF2R SH3TC1 MYCBP2 TLN1 RAP1GAP2 PXN PLEC ARID1A IL4R MED13	2.33e-07	1105	69	13	35748872
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	DNAJB1 AP1B1 MYCBP2 FXR2 NYNRIN OTUD4 PRRC2A PCM1 DYRK2	3.34e-07	462	69	9	31138677
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IGF2R AP1B1 MYCBP2 FXR2 SUPT6H TLN1 PLEC ARID1A PRRC2A PCM1	6.38e-07	653	69	10	22586326
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	RABL6 DNAJB1 MARS1 TLN1 NKTR PLEC PRRC2A PCM1 HEXIM1 ITPR1	1.21e-06	701	69	10	30196744
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	PCSK5 SETD1A HECW1 BRAF AP1B1 MAP4K1 RIOK3 SSH2 PPIH ARID1A	1.74e-06	730	69	10	34857952
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SETD1A MYCBP2 FXR2 SUPT6H TBC1D12 NKTR ARID1A ITPR1	2.62e-06	440	69	8	34244565
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	2.68e-06	14	69	3	17662146
Pubmed	The cytoplasmic domain of the integrin alpha9 subunit requires the adaptor protein paxillin to inhibit cell spreading but promotes cell migration in a paxillin-independent manner.	PXN ITGA9	3.88e-06	2	69	2	11598204
Pubmed	ON pathway mutations increase susceptibility to form-deprivation myopia.	GRM6 ITPR1	3.88e-06	2	69	2	26072023
Pubmed	ERK5 is activated by oncogenic BRAF and promotes melanoma growth.	BRAF MAPK7	3.88e-06	2	69	2	29483645
Pubmed	Ultrastructural localization of GPR179 and the impact of mutant forms on retinal function in CSNB1 patients and a mouse model.	GRM6 GPR179	3.88e-06	2	69	2	24084093
Pubmed	Crystal structure of human LDB1 in complex with SSBP2.	LDB1 SSBP2	3.88e-06	2	69	2	31892537
Pubmed	Requirement for ssbp2 in hematopoietic stem cell maintenance and stress response.	LDB1 SSBP2	3.88e-06	2	69	2	25238756
Pubmed	C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.	AP1B1 MARS1 TLN1 OTUD4 PRRC2A	4.07e-06	119	69	5	35776542
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SLC8A2 RAP1GAP AP1B1 MARS1 TLN1 SPTB OTUD4 KCNQ3 SSH2 PLEC ARID1A PRRC2A PCM1	4.14e-06	1431	69	13	37142655
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	RABL6 MAPKAP1 RAP1GAP AP1B1 TBC1D12 RAP1GAP2 PXN OTUD4 RIOK3 SSH2 MAPK7	5.95e-06	1038	69	11	26673895
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAPKAP1 DNAJB1 RAP1GAP BRAF MYCBP2 MAP4K1 SSH2 PLEC PCM1 DYRK2	7.46e-06	861	69	10	36931259
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	LDB1 BRAF PLEC ARID1A ITPR1	1.14e-05	147	69	5	16959763
Pubmed	FAK promotes recruitment of talin to nascent adhesions to control cell motility.	TLN1 PXN	1.16e-05	3	69	2	22270917
Pubmed	The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation.	SETD1A SUPT6H	1.16e-05	3	69	2	22843687
Pubmed	Ssdp proteins bind to LIM-interacting co-factors and regulate the activity of LIM-homeodomain protein complexes in vivo.	LDB1 SSBP2	1.16e-05	3	69	2	12642495
Pubmed	p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl.	TLN1 PXN	1.16e-05	3	69	2	8641358
Pubmed	Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.	BRAF MAPK7	1.16e-05	3	69	2	26959608
Pubmed	The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury.	RIPK3 BRAF	1.16e-05	3	69	2	24901049
Pubmed	Cell adhesion-dependent serine 85 phosphorylation of paxillin modulates focal adhesion formation and haptotactic migration via association with the C-terminal tail domain of talin.	TLN1 PXN	1.16e-05	3	69	2	22761432
Pubmed	Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection.	TLN1 PXN	1.16e-05	3	69	2	21763488
Pubmed	Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells.	TLN1 PXN	1.16e-05	3	69	2	25391654
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	BRAF AP1B1 MAP4K1 TLN1 PXN NKTR PLEC MAPK7 HEXIM1 DYRK2	1.20e-05	910	69	10	36736316
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	IGF2R LDB1 HECW1 AP1B1 MYCBP2 FXR2 OTUD4 SSH2 PRRC2A PCM1	1.96e-05	963	69	10	28671696
Pubmed	Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.	TLN1 PXN	2.32e-05	4	69	2	20308429
Pubmed	Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion.	TLN1 PXN	2.32e-05	4	69	2	9442086
Pubmed	Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins.	TLN1 PXN	2.32e-05	4	69	2	9054445
Pubmed	Single-stranded DNA-binding proteins regulate the abundance of LIM domain and LIM domain-binding proteins.	LDB1 SSBP2	2.32e-05	4	69	2	17437998
Pubmed	Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development.	LDB1 SSBP2	2.32e-05	4	69	2	12381786
Pubmed	Mutation screening of the LRIT3, CABP4, and GPR179 genes in Chinese patients with Schubert-Bornschein congenital stationary night blindness.	GRM6 GPR179	2.32e-05	4	69	2	27428514
Pubmed	Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.	GRM6 GPR179	2.32e-05	4	69	2	22896717
Pubmed	Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade.	RAP1GAP MAPK7	2.32e-05	4	69	2	17003042
Pubmed	MLKL deficiency in BrafV600EPten-/- melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice.	RIPK3 BRAF	2.32e-05	4	69	2	35422482
Pubmed	SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.	THSD4 FXR2 PLEC PRRC2A HEXIM1	2.50e-05	173	69	5	23979707
Pubmed	LRIT3 is Required for Nyctalopin Expression and Normal ON and OFF Pathway Signaling in the Retina.	GRM6 GPR179	3.86e-05	5	69	2	31959619
Pubmed	Quantification of integrin receptor agonism by fluorescence lifetime imaging.	TLN1 PXN	3.86e-05	5	69	2	18216331
Pubmed	BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor.	BANK1 ITPR1	3.86e-05	5	69	2	11782428
Pubmed	SWI/SNF Complex Mutations Promote Thyroid Tumor Progression and Insensitivity to Redifferentiation Therapies.	BRAF ARID1A	3.86e-05	5	69	2	33318036
Pubmed	Cyclic AMP-independent involvement of Rap1/B-Raf in the angiotensin II AT2 receptor signaling pathway in NG108-15 cells.	RAP1GAP BRAF	3.86e-05	5	69	2	12464615
Pubmed	An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.	FFAR2 ITPR1	3.86e-05	5	69	2	26075576
Pubmed	Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.	TLN1 PXN	3.86e-05	5	69	2	7534286
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	BRAF MYCBP2 TLN1 SPTB PCM1	3.91e-05	190	69	5	15161933
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DNAJB1 IGF2R MYCBP2 GOLM2 PXN OTUD4 SSH2 ARID1A PRRC2A ITPR1	4.05e-05	1049	69	10	27880917
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MAPKAP1 PCSK5 RAP1GAP AP1B1 NOA1 RECQL4 HEXIM1 ITPR1	4.37e-05	650	69	8	38777146
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SLC8A2 TLN1 RAP1GAP2 OTUD4	5.62e-05	104	69	4	10470851
Pubmed	Genotype and phenotype of 101 dutch patients with congenital stationary night blindness.	GRM6 GPR179	5.79e-05	6	69	2	23714322
Pubmed	GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.	GRM6 GPR179	5.79e-05	6	69	2	24790204
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	DNAJB1 AP1B1 MYCBP2 MARS1 TLN1 PPIH ARID1A PRRC2A PCM1 HEXIM1	6.15e-05	1103	69	10	34189442
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DNAJB1 NOA1 TLN1 NKTR PLEC PPIH DUS3L PRRC2A HEXIM1	8.08e-05	916	69	9	32203420
Pubmed	LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation.	GRM6 GPR179	8.09e-05	7	69	2	25997951
Pubmed	Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions.	RAP1GAP RAP1GAP2	8.09e-05	7	69	2	16076873
Pubmed	Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma.	BRAF MYCBP2	8.09e-05	7	69	2	36038253
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	AP1B1 MARS1 TLN1 SPTB PLEC PRRC2A	8.17e-05	360	69	6	33111431
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	DNAJB1 AP1B1 MYCBP2 FXR2 MARS1 TLN1 OTUD4 PLEC PPIH PRRC2A	8.63e-05	1149	69	10	35446349
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	DNAJB1 MYCBP2 FXR2 TLN1 PXN OTUD4 PLEC PRRC2A	9.27e-05	724	69	8	36232890
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	MAPKAP1 PXN ARID1A PRRC2A MED13 RABGGTB ITPR1	9.39e-05	536	69	7	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	MAPKAP1 PXN ARID1A PRRC2A MED13 RABGGTB ITPR1	9.60e-05	538	69	7	10512203
Pubmed	Defining the membrane proteome of NK cells.	IGF2R MYCBP2 FXR2 MARS1 MAP4K1 RECQL4 PRRC2A MED13 PCM1 ITPR1	9.88e-05	1168	69	10	19946888
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	DNAJB1 AP1B1 FXR2 MARS1 SUPT6H TLN1 PLEC PPIH PRRC2A RABGGTB HEXIM1	1.01e-04	1415	69	11	28515276
Pubmed	β2 integrin adhesion complexes maintain the integrity of HIV-1 assembly compartments in primary macrophages.	TLN1 PXN	1.08e-04	8	69	2	22017400
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	DNAJB1 SETD1A MYCBP2 TLN1 ARID1A PRRC2A PCM1	1.09e-04	549	69	7	38280479
Pubmed	Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors.	GRM6 GPR179	1.38e-04	9	69	2	30282023
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	TLN1 PXN	1.38e-04	9	69	2	11807098
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BRAF MYCBP2 MAP4K1 OTUD4 PLEC PRRC2A MED13 PCM1	1.47e-04	774	69	8	15302935
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	DNAJB1 IGF2R MYCBP2 FXR2 SUPT6H OTUD4 PLEC PPIH PRRC2A	1.62e-04	1005	69	9	19615732
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MAPKAP1 DNAJB1 MARS1 SUPT6H NOA1 TLN1 PXN OTUD4 PRRC2A MED13 HEXIM1	1.66e-04	1497	69	11	31527615
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	BRAF FXR2 MARS1 TLN1 PXN OTUD4 ARID1A PRRC2A MED13 HEXIM1	1.68e-04	1247	69	10	27684187
Pubmed	Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation.	TLN1 PXN	1.73e-04	10	69	2	11113628
Pubmed	Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions.	SPTB PLEC	1.73e-04	10	69	2	14627610
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	LDB1 SSBP2 ARID1A MED13 HEXIM1	1.97e-04	268	69	5	33640491
Pubmed	The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors.	GRM6 GPR179	2.11e-04	11	69	2	28262416
Pubmed	Single-stranded DNA binding proteins are required for LIM complexes to induce transcriptionally active chromatin and specify spinal neuronal identities.	LDB1 SSBP2	2.11e-04	11	69	2	26965372
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	RAP1GAP LDB1 MYCBP2 SPTB RAP1GAP2 PLEC ARID1A PRRC2A MED13 PCM1	2.14e-04	1285	69	10	35914814
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	FXR2 MARS1 SUPT6H RECQL4 ARID1A PRRC2A HEXIM1	2.18e-04	615	69	7	31048545
Pubmed	A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.	SETD1A MARS1 ARID1A	2.48e-04	61	69	3	20305087
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	DNAJB1 BRAF AP1B1 NYNRIN ARID1A PCM1	2.61e-04	446	69	6	24255178
Pubmed	Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.	IGF2R TLN1 PXN PLEC CD99L2	2.61e-04	285	69	5	21423176
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	MAPKAP1 DNAJB1 MYCBP2 CENPH PXN SSBP2 NKTR PLEC PPIH DYRK2	2.67e-04	1321	69	10	27173435
Pubmed	Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma.	RIPK3 PRRC2A	2.98e-04	13	69	2	17827388
Pubmed	Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors.	GRM6 GPR179	2.98e-04	13	69	2	36179691
Pubmed	A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.	DNAJB1 MYCBP2 RNF19B PPIH	3.10e-04	162	69	4	21890473
Pubmed	140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.	RAP1GAP AP1B1 GADL1 ITPR1	3.17e-04	163	69	4	16512683
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SETD1A MYCBP2 MARS1 TLN1 RECQL4 RIOK3 PLEC PPIH ARID1A DUS3L	3.23e-04	1353	69	10	29467282
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	BRAF AP1B1 FXR2 TLN1 OTUD4 NKTR PLEC PPIH PRRC2A PCM1	3.59e-04	1371	69	10	36244648
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	RABL6 SUPT6H OTUD4 PRRC2A PCM1 ITPR1	3.64e-04	475	69	6	31040226
Pubmed	Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.	NKTR PPIH	4.01e-04	15	69	2	20676357
Pubmed	FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.	MYCBP2 MED13	4.01e-04	15	69	2	31285543
Pubmed	Large-scale analysis of the human ubiquitin-related proteome.	DNAJB1 MYCBP2 RNF19B RIOK3 PPIH	4.01e-04	313	69	5	16196087
Pubmed	Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.	DNAJB1 MYCBP2 RNF19B PPIH	4.61e-04	180	69	4	21139048
Pubmed	Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.	FXR2 TLN1 PXN OTUD4 PLEC	4.89e-04	327	69	5	15592455
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	DNAJB1 IGF2R MARS1 TLN1 PXN PLEC PPIH	5.04e-04	707	69	7	19738201
Pubmed	Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma.	SUPT6H GOLM2	5.18e-04	17	69	2	36352191
Interaction	YWHAZ interactions	MAPKAP1 SLC8A2 RAP1GAP LDB1 BRAF MYCBP2 RECQL4 RAP1GAP2 OTUD4 SSH2 PLEC MAPK7 ARID1A PRRC2A PCM1 HEXIM1 ITPR1	9.86e-07	1319	67	17	int:YWHAZ
Interaction	TOP3B interactions	RABL6 PCSK5 SETD1A IGF2R SH3TC1 MYCBP2 FXR2 TLN1 SPTB RAP1GAP2 PXN OTUD4 PLEC ARID1A PRRC2A IL4R MED13	4.33e-06	1470	67	17	int:TOP3B
Interaction	PRRC2C interactions	MYCBP2 FXR2 TLN1 RECQL4 OTUD4 MAPK7 PRRC2A RABGGTB	5.22e-06	290	67	8	int:PRRC2C
Interaction	HSPA6 interactions	DNAJB1 BRAF SUPT6H TLN1 RECQL4 PXN HEXIM1 DYRK2	8.70e-06	311	67	8	int:HSPA6
Interaction	BAG2 interactions	DNAJB1 SETD1A SUPT6H TLN1 RECQL4 PXN OTUD4 MAPK7 PPIH NOTCH3	3.71e-05	622	67	10	int:BAG2
Interaction	TBR1 interactions	LDB1 MYCBP2 RECQL4 ARID1A HEXIM1	3.71e-05	113	67	5	int:TBR1
Interaction	PYCR3 interactions	DNAJB1 FXR2 SUPT6H RECQL4 HEXIM1	3.71e-05	113	67	5	int:PYCR3
Interaction	YWHAQ interactions	MAPKAP1 SLC8A2 RAP1GAP BRAF MYCBP2 TLN1 SPTB RECQL4 SSH2 PLEC BANK1 PCM1 HEXIM1	6.78e-05	1118	67	13	int:YWHAQ
Cytoband	22q11.21	RIMBP3 RIMBP3C RIMBP3B	6.42e-04	111	69	3	22q11.21
Cytoband	8q24	KCNQ3 PLEC	8.21e-04	28	69	2	8q24
GeneFamily	Cyclophilin peptidylprolyl isomerases	NKTR PPIH	7.58e-04	19	39	2	909
Coexpression	HADDAD_B_LYMPHOCYTE_PROGENITOR	IGF2R AP1B1 SH3TC1 SSBP2 BANK1 ITPR1 DYRK2	1.03e-05	290	68	7	M939
Coexpression	FAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON	RAP1GAP ERICH3 RAP1GAP2 PLEC ITPR1	7.24e-05	166	68	5	M39026
Coexpression	GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP	TGFBR3 SSBP2 SSH2 ARID1A PCM1	8.33e-05	171	68	5	M2947
Coexpression	GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP	HECW1 SSBP2 MED13	1.32e-04	38	68	3	M1801
Coexpression	GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP	HECW1 SSBP2 MED13	1.32e-04	38	68	3	MM481
Coexpression	GSE26928_EFF_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN	PCSK5 MYCBP2 KCNQ3 SSBP2 RABGGTB	1.51e-04	194	68	5	M4687
Coexpression	GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP	TGFBR3 AP1B1 MAP4K1 SSBP2 IL4R	1.51e-04	194	68	5	M4213
Coexpression	GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP	DNAJB1 MYCBP2 RAP1GAP2 SSBP2 DYRK2	1.62e-04	197	68	5	M5295
Coexpression	GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN	RIPK3 NKTR SSH2 MED13 PCM1	1.62e-04	197	68	5	M8464
Coexpression	GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP	DNAJB1 RAP1GAP2 PXN NKTR DYRK2	1.66e-04	198	68	5	M5293
Coexpression	ONO_FOXP3_TARGETS_DN	TGFBR3 FFAR2 IL4R	1.66e-04	41	68	3	M1982
Coexpression	GSE13493_DP_VS_CD8POS_THYMOCYTE_UP	LDB1 ARID1A CD99L2 IL4R MED13	1.70e-04	199	68	5	M3314
Coexpression	GSE45365_WT_VS_IFNAR_KO_CD8A_DC_MCMV_INFECTION_UP	SH3TC1 SUPT6H TLN1 OTUD4 ARID1A	1.70e-04	199	68	5	M9964
Coexpression	GSE40273_XBP1_KO_VS_WT_TREG_DN	MYCBP2 FFAR2 RAP1GAP2 PLEC CDON	1.70e-04	199	68	5	M9124
Coexpression	GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_UP	BRAF GOLM2 SSH2 HEXIM1 DYRK2	1.74e-04	200	68	5	M6415
Coexpression	GSE411_WT_VS_SOCS3_KO_MACROPHAGE_DN	SETD1A MYCBP2 LIAT1 ARID1A PCM1	1.74e-04	200	68	5	M5991
Coexpression	GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP	DNAJB1 MYCBP2 SSBP2 IL4R PCM1	1.74e-04	200	68	5	M5819
Coexpression	GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_DN	MYCBP2 LIAT1 RNF19B SSBP2 CDON	1.74e-04	200	68	5	M9335
Coexpression	GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN	MYCBP2 SSBP2 ARID1A IL4R PCM1	1.74e-04	200	68	5	M5837
Coexpression	GSE27786_BCELL_VS_NKTCELL_UP	SH3TC1 RNF19B PPIH MED13 HEXIM1	1.74e-04	200	68	5	M4808
Coexpression	GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP	IGF2R BRAF TBC1D12 MAPK7 BANK1	1.74e-04	200	68	5	M7856
Coexpression	GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_UP	RIPK3 MARS1 CENPH FFAR2 RECQL4	1.74e-04	200	68	5	M6553
Coexpression	GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP	IGF2R MARS1 MAP4K1 CD99L2 IL4R	1.74e-04	200	68	5	M7172
Coexpression	GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_UP	IGF2R LDB1 OTUD4 SSH2 DYRK2	1.74e-04	200	68	5	M7195
Coexpression	GSE38304_MYC_NEG_VS_POS_GC_BCELL_UP	SSBP2 SSH2 IL4R MED13 DYRK2	1.74e-04	200	68	5	M9273
Coexpression	GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP	IGF2R AP1B1 MAP4K1 MAPK7 IL4R	1.74e-04	200	68	5	M5630
Coexpression	ONO_FOXP3_TARGETS_DN	TGFBR3 FFAR2 IL4R	2.19e-04	45	68	3	MM1271
Coexpression	GARY_CD5_TARGETS_UP	BRAF MARS1 MAP4K1 TLN1 ARID1A PRRC2A CD99L2	2.24e-04	473	68	7	M17693
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_LATE_AIRWAY_SMC_CELL	THSD4 TGFBR3 ITGA9 IL4R	2.31e-04	115	68	4	M45671
Coexpression	SENESE_HDAC2_TARGETS_UP	SUPT6H PXN PLEC DUS3L	2.38e-04	116	68	4	M4113
Coexpression	GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_UP	IL4R ITPR1	2.94e-04	10	68	2	M13976
Coexpression	FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN	SETD1A RIOK3 RABGGTB	3.18e-04	51	68	3	M3682
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#3_top-relative-expression-ranked_500	MYCBP2 GOLM2 OTUD4 SSBP2 MED13	3.53e-05	116	68	5	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500_k3
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#5_top-relative-expression-ranked_1000	RABL6 LDB1 FXR2 PXN OTUD4 ARID1A PRRC2A PCM1	6.66e-05	429	68	8	gudmap_developingGonad_e14.5_ testes_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#1_top-relative-expression-ranked_1000	TGFBR3 MYCBP2 GOLM2 OTUD4 MED13	1.16e-04	149	68	5	gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k1
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#1_top-relative-expression-ranked_200	MYCBP2 GOLM2 MED13	1.32e-04	31	68	3	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_200_k1
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_500	MYCBP2 GOLM2 OTUD4 SSBP2 MED13	1.77e-04	163	68	5	gudmap_developingKidney_e15.5_cortic collect duct_500_k4
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#3_top-relative-expression-ranked_1000	RABL6 LDB1 FXR2 OTUD4 ARID1A PRRC2A PCM1	2.04e-04	378	68	7	gudmap_developingGonad_e16.5_testes_1000_k3
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_500	GOLM2 OTUD4 SSBP2 ITPR1	2.36e-04	94	68	4	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k4
CoexpressionAtlas	DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#1_top-relative-expression-ranked_1000	RABL6 LDB1 NYNRIN PXN OTUD4 ARID1A PRRC2A PCM1	2.63e-04	524	68	8	gudmap_developingGonad_e12.5_testes_k1_1000
CoexpressionAtlas	DevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_1000	RABL6 LDB1 NYNRIN RNF19B PXN OTUD4 SSBP2 ARID1A PRRC2A PCM1	2.64e-04	819	68	10	gudmap_developingGonad_e12.5_testes_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_200	GOLM2 OTUD4 SSBP2	2.85e-04	40	68	3	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k4
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#4_top-relative-expression-ranked_500	MYCBP2 GOLM2 SSBP2 MED13	3.74e-04	106	68	4	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_500_k4
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	GOLM2 KCNQ3 ARID1A NOTCH3 CDON DYRK2	6.60e-07	199	69	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HECW1 FXR2 OTUD4 BANK1 HEXIM1	4.56e-06	157	69	5	29622bac6b16bb39cec4319bf4c4f92d33345e8a
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RABL6 PCSK5 IGF2R AP1B1 SH3TC1	7.31e-06	173	69	5	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERICH3 MAP4K1 LIAT1 CENPH CDON	8.39e-06	178	69	5	6178706db4a855d72abc156537604d575624df56
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERICH3 MAP4K1 LIAT1 CENPH CDON	8.39e-06	178	69	5	f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYCBP2 MAP4K1 SSH2 BANK1 ITPR1	9.10e-06	181	69	5	8d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 GADL1 ITGA9	1.01e-05	185	69	5	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 GADL1 ITGA9	1.01e-05	185	69	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC8A2 RAP1GAP HECW1 RAP1GAP2 ITPR1	1.04e-05	186	69	5	84ba666237c18189d7e7556bd92dd953af733c00
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	IGF2R BRAF NKTR MED13 ITPR1	1.09e-05	188	69	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 ITGA9 NOTCH3	1.12e-05	189	69	5	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_monocytic\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2R FFAR2 PXN PLEC IL4R	1.30e-05	195	69	5	ae98215b7b7f22f1aca690920ce6092dc4a3c7db
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2R FFAR2 PXN PLEC IL4R	1.30e-05	195	69	5	6fcab7aa4db958ccad0300adea9aaae52ace5bff
ToppCell	severe-Others-Megakaryocytes\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IGF2R FFAR2 RNF19B PXN IL4R	1.37e-05	197	69	5	fc0864e2de2d9f99084586b467551b6da535d933
ToppCell	(0)_NK_cells-(0)_NK_FCGR3Apos\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PCSK5 TGFBR3 IGF2R RAP1GAP2 PXN	1.40e-05	198	69	5	eba39656c6f699ab297b652ded8cb9727b49593c
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	THSD4 PCSK5 TGFBR3 GADL1 ITGA9	1.44e-05	199	69	5	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	THSD4 PCSK5 TGFBR3 NOTCH3 ITPR1	1.47e-05	200	69	5	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	THSD4 PCSK5 TGFBR3 ITGA9 ITPR1	1.47e-05	200	69	5	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	TCGA-Ovary-Primary_Tumor\|TCGA-Ovary / Sample_Type by Project: Shred V9	LDB1 NYNRIN TLN1 PXN	2.24e-05	106	69	4	14f548be39cec604fbdae0382cbf434fa4049840
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	LDB1 NYNRIN TLN1 PXN	2.24e-05	106	69	4	939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	LDB1 NYNRIN TLN1 PXN	2.24e-05	106	69	4	e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	THSD4 PCSK5 HECW1 ITGA9	1.03e-04	157	69	4	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	343B-Fibroblasts-Fibroblast-D-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SH3TC1 MAP4K1 FFAR2 RNF19B	1.17e-04	162	69	4	7860fab12893d2f589f91a89e33fbffeb4d6c56c
ToppCell	343B-Fibroblasts-Fibroblast-D\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SH3TC1 MAP4K1 FFAR2 RNF19B	1.17e-04	162	69	4	431dec235874245a0289aa1af98bdfb7ffe1c485
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	FXR2 SPTB GADL1 NOTCH3	1.31e-04	167	69	4	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPH FFAR2 RAP1GAP2 PPIH	1.34e-04	168	69	4	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TLN1 RNF19B RAP1GAP2 SSH2	1.34e-04	168	69	4	c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERICH3 FFAR2 RAP1GAP2 GPR179	1.34e-04	168	69	4	17d46f993dc4ae22b8087808582aba77f5c61892
ToppCell	droplet-Lung-nan-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLN1 RNF19B RAP1GAP2 SSH2	1.37e-04	169	69	4	ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCell	droplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLN1 RNF19B RAP1GAP2 SSH2	1.37e-04	169	69	4	c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16\|GI_small-bowel / Manually curated celltypes from each tissue	TGFBR3 IGF2R RAP1GAP2 PXN	1.47e-04	172	69	4	701de463f85aaad3a4b36a0d5fbc416406620089
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	THSD4 LIAT1 SSBP2 ITGA9	1.47e-04	172	69	4	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	droplet-Marrow-nan-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP SH3TC1 MAP4K1 TBC1D12	1.54e-04	174	69	4	55cc8300489d11322724159ec7d0e1d32a702e91
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Naive_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DNAJB1 RIMBP3C IL4R BANK1	1.57e-04	175	69	4	d544f24ee33783ed4afb4d7ec079a4484118bb15
ToppCell	facs-Kidney-nan-18m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPK3 MAP4K1 IL4R BANK1	1.71e-04	179	69	4	f4fd214a9865c635d8a744ce5e0eff45174d3de4
ToppCell	facs-Kidney-nan-18m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPK3 MAP4K1 IL4R BANK1	1.71e-04	179	69	4	57d8d44a793314eec8f77030f4177bfe21d41652
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 ITGA9	1.71e-04	179	69	4	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	IPF-Lymphoid-B\|World / Disease state, Lineage and Cell class	MAP4K1 SSH2 BANK1 ITPR1	1.75e-04	180	69	4	30f9398c9b784f49470847a025bac90687e997a1
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THSD4 HECW1 ITGA9 UNC80	1.79e-04	181	69	4	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	IPF-Lymphoid-B\|IPF / Disease state, Lineage and Cell class	MAP4K1 SSH2 BANK1 ITPR1	1.86e-04	183	69	4	e37d2c015c34471a8a54a0299e94b0371e1ada5a
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 ITGA9	1.86e-04	183	69	4	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 ITGA9	1.94e-04	185	69	4	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 ITGA9	1.98e-04	186	69	4	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	HECW1 MYCBP2 RAP1GAP2 UNC80	1.98e-04	186	69	4	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC8A2 ERICH3 UNC80 GPR179	1.98e-04	186	69	4	15f2e5905486e33f6f7b3b3e9758a0559e8c61ee
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 ITGA9	2.06e-04	188	69	4	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 NYNRIN	2.06e-04	188	69	4	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 NYNRIN	2.06e-04	188	69	4	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 NYNRIN	2.06e-04	188	69	4	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SSBP2 IL4R BANK1 ITPR1	2.06e-04	188	69	4	d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 ITGA9	2.06e-04	188	69	4	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	THSD4 GADL1 ITGA9 IL4R	2.06e-04	188	69	4	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 NOTCH3	2.11e-04	189	69	4	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	THSD4 PCSK5 HECW1 ITGA9	2.11e-04	189	69	4	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	HECW1 MYCBP2 SPTB UNC80	2.15e-04	190	69	4	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	Control-Lymphoid-NK\|Lymphoid / Disease state, Lineage and Cell class	TGFBR3 IGF2R RAP1GAP2 PXN	2.15e-04	190	69	4	1584c68b58c7f406d9b0e8451beea3e6f8980c56
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYCBP2 TLN1 ITGA9 BANK1	2.15e-04	190	69	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	IPF-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	SH3TC1 FFAR2 RAP1GAP2 SSH2	2.15e-04	190	69	4	f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	BRAF IL4R BANK1 ITPR1	2.15e-04	190	69	4	0724665ac8238f2383c3a929d89abf4a48ec2420
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	AP1B1 SH3TC1 SSBP2 ITPR1	2.19e-04	191	69	4	40813c397f533c2f4a6359a77757f736b6d9e07d
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 ITGA9	2.19e-04	191	69	4	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	IPF-Lymphoid-NK\|Lymphoid / Disease state, Lineage and Cell class	TGFBR3 IGF2R RAP1GAP2 PXN	2.19e-04	191	69	4	f2ddc0962007d7a4e78fbd916ebb62fc557d480a
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 ITGA9	2.19e-04	191	69	4	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BRAF IL4R BANK1 ITPR1	2.24e-04	192	69	4	446c61c0d6ba89c619efe87ee495951299953981
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	DNAJB1 NKTR MED13 PCM1	2.24e-04	192	69	4	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 TGFBR3 NOTCH3	2.24e-04	192	69	4	992d08092edbc68c47b945deb8708379738c239a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	BRAF IL4R BANK1 ITPR1	2.28e-04	193	69	4	ac227ddabfb3f021b1b39dba73f898517cd5a58e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFBR3 IGF2R TLN1 RAP1GAP2	2.28e-04	193	69	4	b53ffef20f918b7d1e9d3924562691d13245e2dd
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AP1B1 RAP1GAP2 NKTR UNC80	2.28e-04	193	69	4	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	DNAJB1 NKTR MED13 PCM1	2.28e-04	193	69	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	BRAF IL4R BANK1 ITPR1	2.28e-04	193	69	4	f4135615ee0118eec9e221becdd67888e0c2a112
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-Naive_B_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	AP1B1 IL4R BANK1 ITPR1	2.33e-04	194	69	4	20967afbadb3cf80ba9f4d7ebda4e64389252e70
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AP1B1 MYCBP2 BANK1 ITPR1	2.33e-04	194	69	4	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TGFBR3 IGF2R RAP1GAP2 PXN	2.33e-04	194	69	4	335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FFAR2 GRM6 UNC80 CDON	2.37e-04	195	69	4	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FFAR2 GRM6 UNC80 CDON	2.37e-04	195	69	4	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	E17.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 TGFBR3 SSBP2 ITGA9	2.37e-04	195	69	4	1daddd801bd4596fffbdb822fc326d5127c96004
ToppCell	E17.5-Mesenchymal-myocytic_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 TGFBR3 SSBP2 ITGA9	2.37e-04	195	69	4	01a750d660993017af00736215cbcff2de5909c1
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 NKTR UNC80 PCM1	2.37e-04	195	69	4	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 NKTR UNC80 PCM1	2.37e-04	195	69	4	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBR3 MYCBP2 NKTR PCM1	2.37e-04	195	69	4	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	metastatic_Lymph_Node-T/NK_cells-NK\|metastatic_Lymph_Node / Location, Cell class and cell subclass	TGFBR3 IGF2R RAP1GAP2 PXN	2.42e-04	196	69	4	f69f53e2ac1818b4ad0161b0bd70655e98ef65f0
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	IGF2R TLN1 IL4R ITPR1	2.42e-04	196	69	4	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	10x5'-Liver-Lymphocytic_NK-NK_CD16\|Liver / Manually curated celltypes from each tissue	TGFBR3 IGF2R RAP1GAP2 PXN	2.42e-04	196	69	4	e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCell	control-Others-Megakaryocytes\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IGF2R FFAR2 PXN SSH2	2.42e-04	196	69	4	10d914f1612622f64ac71da04e1995a854a4bec9
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	TGFBR3 IGF2R RAP1GAP2 PXN	2.42e-04	196	69	4	07b557b8530c19ca5b31ad2eac00c36ef1939266
ToppCell	COPD-Stromal-Fibroblast\|Stromal / Disease state, Lineage and Cell class	PCSK5 TGFBR3 PXN CDON	2.42e-04	196	69	4	4930eeb303d174c28fd91021723e26fdf1af9170
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD16\|lymph-node_spleen / Manually curated celltypes from each tissue	TGFBR3 IGF2R RAP1GAP2 PXN	2.42e-04	196	69	4	f7e5a7fad4547e8ab9ab8b140239281832fb4260
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFBR3 IGF2R RAP1GAP2 PXN	2.42e-04	196	69	4	f0566f2ef96584ed6d9247b149218376fb509915
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCSK5 TGFBR3 HECW1 ITGA9	2.47e-04	197	69	4	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IGF2R FFAR2 TLN1 IL4R	2.47e-04	197	69	4	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	Monocytes-NUPR1+_Monocytes\|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	AP1B1 KCNQ3 PLEC RABGGTB	2.47e-04	197	69	4	8a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TGFBR3 IGF2R RAP1GAP2 PXN	2.52e-04	198	69	4	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	mild-Lymphocytic-NK_cells\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TGFBR3 IGF2R TLN1 PXN	2.52e-04	198	69	4	1d20fc9948965de52a98f758035edfdd12cafc5f
ToppCell	(0)_NK_FCGR3Apos\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PCSK5 TGFBR3 IGF2R PXN	2.52e-04	198	69	4	13f10f9233fc1523f0da2d9d59f3ced9c51a603a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW1 KCNQ3 UNC80 ITPR1	2.52e-04	198	69	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW1 KCNQ3 UNC80 ITPR1	2.52e-04	198	69	4	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SPTB GADL1 NOTCH3 ITPR1	2.52e-04	198	69	4	1e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCell	distal-Hematologic-Proliferating_Macrophage-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPH FFAR2 RECQL4 PPIAL4G	2.52e-04	198	69	4	8afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TGFBR3 IGF2R RAP1GAP2 PXN	2.52e-04	198	69	4	aa33be29e26f1b8facfc894413099083ae3bbb1b
Drug	Imipenem [74431-23-5]; Down 200; 13.4uM; HL60; HG-U133A	LDB1 HECW1 RNF19B RIOK3 GRM6 RABGGTB HEXIM1 ITPR1	1.02e-07	194	67	8	1724_DN
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; PC3; HT_HG-U133A	MARS1 SUPT6H TLN1 PXN OTUD4 SSBP2 GRM6 NOTCH3	1.02e-07	194	67	8	4301_DN
Drug	chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A_EA	RAP1GAP SUPT6H PXN NKTR PLEC RABGGTB HEXIM1 DYRK2	1.24e-07	199	67	8	1055_DN
Drug	Tridihexethyl chloride; Up 200; 11.4uM; MCF7; HT_HG-U133A	SETD1A FXR2 SUPT6H PXN PRRC2A NOTCH3 CDON	1.65e-06	194	67	7	3526_UP
Drug	Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A	LDB1 SUPT6H RNF19B PXN PLEC IL4R NOTCH3	1.71e-06	195	67	7	1700_DN
Drug	Lactobionic acid [96-82-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	RABL6 SETD1A LDB1 RNF19B PLEC IL4R PCM1	1.89e-06	198	67	7	3246_DN
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; PC3; HT_HG-U133A	RAP1GAP LDB1 FXR2 MARS1 PLEC MAPK7 CDON	1.89e-06	198	67	7	6603_DN
Drug	Butacaine [149-16-6]; Up 200; 13uM; MCF7; HT_HG-U133A	LDB1 SH3TC1 SUPT6H RNF19B PXN IL4R NOTCH3	1.89e-06	198	67	7	3469_UP
Drug	Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; PC3; HG-U133A	IGF2R LDB1 PXN RIOK3 NKTR ARID1A DYRK2	1.96e-06	199	67	7	1890_DN
Drug	Paclitaxel [33069-62-4]; Down 200; 4.6uM; PC3; HT_HG-U133A	SUPT6H RNF19B PXN SSBP2 PLEC IL4R	2.10e-05	191	67	6	6720_DN
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	FXR2 MARS1 SUPT6H MAPK7 PRRC2A NOTCH3	2.23e-05	193	67	6	3262_UP
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A	SETD1A SH3TC1 FXR2 SUPT6H TLN1 PXN	2.23e-05	193	67	6	4338_DN
Drug	Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A	SH3TC1 SUPT6H PXN SSBP2 MAPK7 IL4R	2.30e-05	194	67	6	4838_UP
Drug	Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; PC3; HT_HG-U133A	FXR2 SUPT6H TLN1 RNF19B PXN ARID1A	2.30e-05	194	67	6	4284_DN
Drug	PNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A	RABL6 SH3TC1 SUPT6H TLN1 SPTB PXN	2.30e-05	194	67	6	4291_DN
Drug	Famprofazone [22881-35-2]; Up 200; 10.6uM; PC3; HT_HG-U133A	SLC8A2 SUPT6H TLN1 PXN MAPK7 ITGA9	2.36e-05	195	67	6	4309_UP
Drug	Luteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A	LDB1 TLN1 RNF19B SSBP2 PCM1 HEXIM1	2.36e-05	195	67	6	5004_DN
Drug	Hesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A	LDB1 SUPT6H TLN1 ARID1A PRRC2A IL4R	2.43e-05	196	67	6	5350_UP
Drug	Flumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A	THSD4 LDB1 KCNQ3 PLEC PCM1 HEXIM1	2.43e-05	196	67	6	3410_UP
Drug	Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A	HECW1 TLN1 PXN MAPK7 IL4R ITPR1	2.43e-05	196	67	6	2296_UP
Drug	Budesonide [51333-22-3]; Down 200; 9.2uM; HL60; HG-U133A	RAP1GAP MARS1 RNF19B RIOK3 PRRC2A DYRK2	2.43e-05	196	67	6	1716_DN
Drug	Brinzolamide [138890-62-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A	PXN KCNQ3 MAPK7 PCM1 HEXIM1 CDON	2.50e-05	197	67	6	3230_DN
Drug	Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; MCF7; HT_HG-U133A	SETD1A SH3TC1 MARS1 RNF19B RAP1GAP2 IL4R	2.50e-05	197	67	6	7412_UP
Drug	Benzonatate [104-31-4]; Up 200; 6.6uM; MCF7; HT_HG-U133A	HECW1 MAP4K1 PXN KCNQ3 PCM1 ITPR1	2.50e-05	197	67	6	5435_UP
Drug	Azapropazone [13539-59-8]; Up 200; 13.4uM; PC3; HT_HG-U133A	LDB1 FXR2 MARS1 RNF19B SSBP2 MAPK7	2.50e-05	197	67	6	7277_UP
Drug	Rolitetracycline [751-97-3]; Down 200; 7.6uM; HL60; HT_HG-U133A	RABL6 MAP4K1 OTUD4 SSBP2 PLEC CDON	2.50e-05	197	67	6	3031_DN
Drug	Aconitine [302-27-2]; Up 200; 6.2uM; PC3; HT_HG-U133A	LDB1 MARS1 PCM1 RABGGTB NOTCH3 DYRK2	2.50e-05	197	67	6	7149_UP
Drug	Chlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A	SETD1A RNF19B MAPK7 ARID1A PCM1 CDON	2.57e-05	198	67	6	2217_DN
Drug	Tetracycline hydrochloride [64-75-5]; Down 200; 8.4uM; PC3; HT_HG-U133A	BRAF FXR2 SUPT6H TLN1 RNF19B MAPK7	2.57e-05	198	67	6	2080_DN
Drug	Vigabatrin [60643-86-9]; Down 200; 31uM; PC3; HT_HG-U133A	LDB1 SSBP2 NKTR PLEC IL4R NOTCH3	2.57e-05	198	67	6	6314_DN
Drug	Urosiol [128-13-2]; Up 200; 10.2uM; PC3; HT_HG-U133A	FXR2 MARS1 RNF19B SSBP2 MAPK7 PCM1	2.57e-05	198	67	6	7243_UP
Drug	Iopamidol [60166-93-0]; Down 200; 5.2uM; MCF7; HT_HG-U133A	RAP1GAP LDB1 AP1B1 SUPT6H TLN1 PRRC2A	2.57e-05	198	67	6	7189_DN
Drug	Riluzole hydrochloride; Down 200; 14.8uM; PC3; HT_HG-U133A	LDB1 SUPT6H RAP1GAP2 NKTR MAPK7 CDON	2.65e-05	199	67	6	7365_DN
Drug	Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; HL60; HT_HG-U133A	LDB1 SUPT6H RNF19B OTUD4 SSBP2 HEXIM1	2.65e-05	199	67	6	2550_DN
Drug	Naproxen [22204-53-1]; Up 200; 17.4uM; HL60; HT_HG-U133A	RAP1GAP SUPT6H OTUD4 MAPK7 PCM1 HEXIM1	2.72e-05	200	67	6	1869_UP
Drug	Acetylsalicylsalicylic acid [530-75-6]; Down 200; 13.4uM; PC3; HT_HG-U133A	RAP1GAP SUPT6H RNF19B MAPK7 ARID1A DYRK2	2.72e-05	200	67	6	2061_DN
Drug	1-piperidinocyclohexanecarbonitrile	BRAF PLEC NOTCH3	5.35e-05	25	67	3	CID000062529
Drug	5182598; Up 200; 25uM; MCF7; HT_HG-U133A_EA	DNAJB1 LDB1 MARS1 SUPT6H PRRC2A	1.75e-04	177	67	5	976_UP
Drug	DHPN	IGF2R MAP4K1 PLEC	2.06e-04	39	67	3	CID000040828
Drug	17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB1 PXN RIOK3 RABGGTB CDON	2.10e-04	184	67	5	5210_UP
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	IGF2R PXN PLEC ARID1A DYRK2	2.32e-04	188	67	5	4845_DN
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A	HECW1 SUPT6H TLN1 PXN MAPK7	2.44e-04	190	67	5	4274_UP
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	LDB1 NKTR PLEC ARID1A NOTCH3	2.50e-04	191	67	5	1057_DN
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA	RABL6 MARS1 RNF19B IL4R NOTCH3	2.50e-04	191	67	5	991_DN
Drug	wortmannin from Penicillium funiculosum; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA	DNAJB1 MARS1 RNF19B PLEC NOTCH3	2.50e-04	191	67	5	1023_DN
Drug	Risperidone [106266-06-2]; Down 200; 9.8uM; HL60; HT_HG-U133A	RABL6 LDB1 RNF19B NKTR DYRK2	2.56e-04	192	67	5	2947_DN
Drug	Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	SETD1A TLN1 RNF19B PXN ITPR1	2.56e-04	192	67	5	4342_DN
Drug	PHA-00851261E [724719-49-7]; Down 200; 10uM; PC3; HT_HG-U133A	SETD1A SUPT6H TLN1 RNF19B PXN	2.56e-04	192	67	5	4330_DN
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	THSD4 DNAJB1 SPTB MAPK7 ITPR1	2.62e-04	193	67	5	5914_UP
Drug	Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TLN1 PXN NKTR PLEC PCM1	2.62e-04	193	67	5	4846_DN
Drug	Omeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	SUPT6H RNF19B KCNQ3 ITGA9 DYRK2	2.68e-04	194	67	5	2828_UP
Drug	Diphenidol hydrochloride [3254-89-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A	SUPT6H RAP1GAP2 PXN RIOK3 PLEC	2.68e-04	194	67	5	7406_DN
Drug	Vincamine [1617-90-9]; Down 200; 11.2uM; PC3; HT_HG-U133A	TLN1 SPTB PXN OTUD4 ITPR1	2.68e-04	194	67	5	4341_DN
Drug	Benfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A	FXR2 SUPT6H MAP4K1 PCM1 ITPR1	2.68e-04	194	67	5	2621_UP
Drug	Acyclovir [59277-89-3]; Down 200; 17.8uM; MCF7; HT_HG-U133A	FXR2 FFAR2 RNF19B PLEC MAPK7	2.68e-04	194	67	5	5278_DN
Drug	ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A	FXR2 SUPT6H ARID1A IL4R DYRK2	2.75e-04	195	67	5	1630_UP
Drug	Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A	LDB1 HECW1 RNF19B PXN MAPK7	2.75e-04	195	67	5	2853_UP
Drug	ST021200; Down 200; 10uM; PC3; HT_HG-U133A	SPTB PXN SSBP2 PLEC BANK1	2.75e-04	195	67	5	7493_DN
Drug	Triflusal [322-79-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A	AP1B1 SUPT6H NKTR RABGGTB ITPR1	2.75e-04	195	67	5	2867_DN
Drug	Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; HL60; HT_HG-U133A	SETD1A RAP1GAP MAP4K1 ARID1A BANK1	2.75e-04	195	67	5	2446_DN
Drug	Flumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A	SH3TC1 FXR2 MAPK7 BANK1 ITPR1	2.75e-04	195	67	5	4734_UP
Drug	ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A	TGFBR3 FXR2 MAPK7 ITPR1 DYRK2	2.75e-04	195	67	5	6918_UP
Drug	Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	TGFBR3 SETD1A LDB1 FXR2 IL4R	2.75e-04	195	67	5	5388_DN
Drug	Carbamazepine [298-46-4]; Down 200; 17uM; PC3; HT_HG-U133A	RAP1GAP ARID1A PCM1 NOTCH3 CDON	2.75e-04	195	67	5	5093_DN
Drug	Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A	HECW1 TLN1 PXN MAPK7 IL4R	2.75e-04	195	67	5	4813_UP
Drug	novobiocin sodium, USP; Down 200; 100uM; SKMEL5; HG-U133A	LDB1 MAPK7 PRRC2A MED13 PCM1	2.75e-04	195	67	5	632_DN
Drug	Felodipine [72509-76-3]; Up 200; 10.4uM; PC3; HT_HG-U133A	THSD4 SETD1A SUPT6H TLN1 RNF19B	2.75e-04	195	67	5	6695_UP
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A	SETD1A BRAF SH3TC1 MARS1 PCM1	2.75e-04	195	67	5	3755_DN
Drug	Ursolic acid [77-52-1]; Down 200; 8.8uM; PC3; HT_HG-U133A	RABL6 AP1B1 SUPT6H MAPK7 DYRK2	2.75e-04	195	67	5	5825_DN
Drug	PHA-00851261E [724719-49-7]; Down 200; 10uM; MCF7; HT_HG-U133A	BRAF KCNQ3 PCM1 CDON DYRK2	2.81e-04	196	67	5	3965_DN
Drug	indomethacin, USP; Up 200; 100uM; SKMEL5; HG-U133A	RAP1GAP SPTB NKTR PLEC RABGGTB	2.81e-04	196	67	5	503_UP
Drug	17-AAG; Up 200; 1uM; PC3; HT_HG-U133A	DNAJB1 HECW1 MARS1 KCNQ3 PCM1	2.81e-04	196	67	5	5919_UP
Drug	Neomycin sulfate [1405-10-3]; Down 200; 4.2uM; MCF7; HT_HG-U133A	SETD1A LDB1 PXN ARID1A PCM1	2.81e-04	196	67	5	2229_DN
Drug	Panthenol (D) [81-13-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A	RNF19B PXN NKTR IL4R HEXIM1	2.81e-04	196	67	5	7455_DN
Drug	(-)-Quinpirole hydrochloride [85760-74-3]; Up 200; 15.6uM; MCF7; HT_HG-U133A	LDB1 MARS1 PXN PLEC CDON	2.81e-04	196	67	5	3539_UP
Drug	Oxybenzone [131-57-7]; Down 200; 17.6uM; PC3; HT_HG-U133A	RABL6 SUPT6H TLN1 NKTR MAPK7	2.81e-04	196	67	5	6309_DN
Drug	quercetin dihydrate; Up 200; 1uM; MCF7; HG-U133A	SETD1A IGF2R SUPT6H PXN PLEC	2.81e-04	196	67	5	283_UP
Drug	Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A	MARS1 SUPT6H PXN MAPK7 ARID1A	2.81e-04	196	67	5	3256_UP
Drug	Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A	SETD1A MAPK7 ARID1A IL4R ITPR1	2.81e-04	196	67	5	2318_DN
Drug	Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	BRAF MARS1 RNF19B PXN KCNQ3	2.81e-04	196	67	5	4143_DN
Drug	Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A	RAP1GAP FXR2 RNF19B PXN PCM1	2.81e-04	196	67	5	5679_DN
Drug	Nomegestrol acetate [58652-20-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A	FFAR2 RNF19B PXN MAPK7 ITPR1	2.81e-04	196	67	5	5461_UP
Drug	Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; PC3; HT_HG-U133A	RABL6 SH3TC1 RNF19B PCM1 CDON	2.81e-04	196	67	5	3702_DN
Drug	Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	SUPT6H TLN1 PXN PLEC MAPK7	2.81e-04	196	67	5	5341_UP
Drug	Epitiostanol [2363-58-8]; Down 200; 13uM; PC3; HT_HG-U133A	TLN1 PXN NKTR MAPK7 NOTCH3	2.81e-04	196	67	5	4204_DN
Drug	Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; PC3; HT_HG-U133A	FXR2 RNF19B MAPK7 BANK1 NOTCH3	2.81e-04	196	67	5	7251_UP
Drug	Sulpiride [15676-16-1]; Up 200; 11.8uM; HL60; HG-U133A	RABL6 SUPT6H PLEC ITPR1 DYRK2	2.81e-04	196	67	5	1967_UP
Drug	Fluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; PC3; HT_HG-U133A	RABL6 PXN MAPK7 CDON ITPR1	2.81e-04	196	67	5	6757_DN
Drug	Colistin sulfate [1264-72-8]; Up 200; 3uM; MCF7; HT_HG-U133A	TGFBR3 MARS1 SUPT6H FFAR2 PCM1	2.81e-04	196	67	5	2851_UP
Drug	(+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; HL60; HT_HG-U133A	PCSK5 TGFBR3 MAP4K1 SSBP2 BANK1	2.81e-04	196	67	5	3016_UP
Drug	Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; PC3; HT_HG-U133A	RNF19B TBC1D12 MAPK7 ARID1A DYRK2	2.81e-04	196	67	5	6338_UP
Drug	0316684-0000 [391209-55-5]; Down 200; 10uM; PC3; HT_HG-U133A	SETD1A NYNRIN SPTB PXN MAPK7	2.81e-04	196	67	5	7057_DN
Drug	fludrocortisone acetate; Up 200; 1uM; MCF7; HG-U133A	IGF2R SUPT6H PXN PLEC PCM1	2.88e-04	197	67	5	282_UP
Drug	Dichlorphenamide [120-97-8]; Down 200; 13.2uM; HL60; HT_HG-U133A	RNF19B SSBP2 PLEC MAPK7 BANK1	2.88e-04	197	67	5	3027_DN
Drug	Levonordefrin [829-74-3]; Down 200; 21.8uM; MCF7; HT_HG-U133A	LDB1 PXN SSBP2 NKTR IL4R	2.88e-04	197	67	5	7208_DN
Drug	Salbutamol [18559-94-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A	LDB1 MARS1 PXN IL4R ITPR1	2.88e-04	197	67	5	2306_DN
Drug	Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; PC3; HT_HG-U133A	TLN1 PXN NKTR MAPK7 PCM1	2.88e-04	197	67	5	6747_DN
Drug	Mesalamine [89-57-6]; Down 200; 26.2uM; MCF7; HT_HG-U133A	BRAF SUPT6H PLEC IL4R CDON	2.88e-04	197	67	5	7241_DN
Drug	Prochlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A	LDB1 AP1B1 PXN ARID1A PRRC2A	2.88e-04	197	67	5	2641_DN
Drug	Pyrilamine maleate [59-33-6]; Down 200; 10uM; MCF7; HT_HG-U133A	BRAF RIOK3 IL4R RABGGTB NOTCH3	2.88e-04	197	67	5	7223_DN
Disease	Melanoma, Cloudman S91	BRAF PXN	9.06e-05	7	62	2	C0009075
Disease	Melanoma, Experimental	BRAF PXN	9.06e-05	7	62	2	C0025205
Disease	Melanoma, B16	BRAF PXN	9.06e-05	7	62	2	C0004565
Disease	Melanoma, Harding-Passey	BRAF PXN	9.06e-05	7	62	2	C0018598
Disease	Gastrointestinal Stromal Tumors	BRAF CDON DYRK2	1.61e-04	50	62	3	C0238198
Disease	mean reticulocyte volume	SETD1A RAP1GAP LDB1 NYNRIN SPTB TBC1D12 OTUD4 PCM1	2.59e-04	799	62	8	EFO_0010701
Disease	X-Linked Csnb	GRM6 GPR179	2.83e-04	12	62	2	C3711543
Disease	Night blindness, congenital stationary, type 1	GRM6 GPR179	2.83e-04	12	62	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	GRM6 GPR179	2.83e-04	12	62	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	GRM6 GPR179	2.83e-04	12	62	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	GRM6 GPR179	2.83e-04	12	62	2	C1848172
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	GRM6 GPR179	2.83e-04	12	62	2	C1850362
Disease	Cone-rod synaptic disorder, congenital nonprogressive	GRM6 GPR179	3.34e-04	13	62	2	C4041558
Disease	Replication Error Phenotype	BRAF ARID1A	4.48e-04	15	62	2	C1721098
Disease	Microsatellite Instability	BRAF ARID1A	4.48e-04	15	62	2	C0920269
Disease	sexual dimorphism measurement	PCSK5 RIPK3 MARS1 NYNRIN OTUD4 RIOK3 PLEC ARID1A BANK1	4.81e-04	1106	62	9	EFO_0021796
Disease	Night blindness, congenital stationary	GRM6 GPR179	5.79e-04	17	62	2	C0339535
Disease	serum gamma-glutamyl transferase measurement	THSD4 TLN1 TBC1D12 ITGA9 ARID1A PRRC2A MED13 ITPR1	6.33e-04	914	62	8	EFO_0004532
Disease	primary ciliary dyskinesia (implicated_via_orthology)	PCSK5 AP1B1	7.26e-04	19	62	2	DOID:9562 (implicated_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	MAP4K1 SSH2 ARID1A NOTCH3	7.65e-04	195	62	4	DOID:1574 (implicated_via_orthology)
Disease	type 1 diabetes mellitus (is_implicated_in)	IGF2R PRRC2A BANK1	7.72e-04	85	62	3	DOID:9744 (is_implicated_in)
Disease	grip strength measurement	THSD4 GADL1 PRRC2A BANK1 ITPR1	8.49e-04	350	62	5	EFO_0006941
Disease	Granulomatous Slack Skin	BRAF ARID1A	9.77e-04	22	62	2	C0376407
Disease	Lymphoma, T-Cell, Cutaneous	BRAF ARID1A	1.07e-03	23	62	2	C0079773
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	PCSK5 NYNRIN ARID1A	1.20e-03	99	62	3	EFO_0004611, EFO_0007878
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	PCSK5 NYNRIN ARID1A	1.31e-03	102	62	3	EFO_0004329, EFO_0004611
Disease	Cholangiocarcinoma	BRAF ARID1A	1.37e-03	26	62	2	C0206698
Disease	Sezary Syndrome	BRAF ARID1A	1.47e-03	27	62	2	C0036920
Disease	fibrinogen measurement	PLEC NOTCH3 ITPR1	1.58e-03	109	62	3	EFO_0004623
Disease	aspartate aminotransferase to alanine aminotransferase ratio	NYNRIN RECQL4 PLEC ARID1A	1.62e-03	239	62	4	EFO_0010934
Disease	Malignant neoplasm of breast	RAP1GAP BRAF NOA1 ITGA9 ARID1A GRM6 PRRC2A NOTCH3	1.78e-03	1074	62	8	C0006142

Protein segments in the cluster

Peptide	Gene	Start	Entry
EGMTNGDSGFLPGRD	TBC1D12	131	O60347
EANEMEGEGKQNGSG	BANK1	451	Q8NDB2
DRNSEGDGDMEGEGN	ERICH3	1311	Q5RHP9
GDGDMEGEGNTQKNE	ERICH3	1316	Q5RHP9
QALFNGDMEPEAGAG	BRAF	16	P15056
GNQEGGDSGPDSSDM	CT47B1	31	P0C2W7
LMGDEPEGIGGTNFV	AP1B1	666	Q10567
MAEGTAEAPLENGGG	DUS3L	1	Q96G46
FGQRNGEEGMDIDDP	DNAJB1	116	P25685
DFMIQGGDFVNGDGT	PPIH	71	O43447
MEAAVGVPDGGDQGG	OTUD4	1	Q01804
DSDGEALGGNPMVAG	RABL6	426	Q3YEC7
AALDYDPGDGQMGGQ	RIMBP3B	1576	A6NNM3
AALDYDPGDGQMGGQ	RIMBP3C	1576	A6NJZ7
QDGGAGKGPADMASQ	ARID1A	321	O14497
DMGVADGPQDGQADS	MAPK7	756	Q13164
NEDRGVGQGEGMPSS	FFAR2	311	O15552
GEPTLMGGEFGDEDE	LDB1	341	Q86U70
DGGLESDGPNMTENG	FXR2	561	P51116
PEGQNSGTAGESMGA	GPR179	1111	Q6PRD1
GQGPDETMDGASGEN	ITPR1	1146	Q14643
GDQGMVSVGPEGAGE	HECW1	426	Q76N89
GTGDPMAEDRGYGND	KCNQ3	491	O43525
FMEEGGEEDGGSDGM	HEXIM1	241	O94992
MATGGGPFEDGMNDQ	PCM1	1	Q15154
GPGFYGDQEMGECES	PCSK5	1116	Q92824
DADGMDVNVRGPDGF	NOTCH3	1776	Q9UM47
RSSPGGQDEGGFMAQ	PXN	301	P49023
QDEETGGFADRPGDM	RABGGTB	271	P53611
FGQSISGGIDMDGNG	ITGA9	426	Q13797
SGGIDMDGNGYPDVT	ITGA9	431	Q13797
MCQGGDFTHPNGTGD	PPIAL4G	61	P0DN37
GEENGGFCQQDMGES	IL4R	416	P24394
NGSAGTPVMFNENGD	GRM6	451	O15303
GSNDDPGSGMVAEPG	CD99L2	171	Q8TCZ2
QMQDADEPADSGGEG	CENPH	6	Q9H3R5
RNEADGMPINVGDGG	CNTF	136	P26441
GSEDPAEFSRGQEGM	CDON	1201	Q4KMG0
EGDGIFNPGGSVSNM	GADL1	171	Q6ZQY3
RQGMTGGPNNGGYDD	DYRK2	191	Q92630
PVDTEGFGEGGDMQE	NOA1	56	Q8NC60
AGGEPGDQGSMQLDF	NYNRIN	491	Q9P2P1
PSDEGPGSMGDDGQL	MAP4K1	406	Q92918
GGDAGMPGIEENDLA	GOLM2	246	Q6P4E1
GVGFDSENPGDDGQM	IGF2R	2281	P11717
DDGEMGGNFLNPFQS	SSBP2	336	P81877
AQMAENEEEGSGGGG	RNF19B	616	Q6ZMZ0
GEAMEEGDSGGSQPS	RAP1GAP2	651	Q684P5
GGAGTMGYKDNDGEE	LIAT1	41	Q6ZQX7
FMIQGGDFSEGNGKG	NKTR	71	P30414
AALDYDPGDGQMGGQ	RIMBP3	1576	Q9UFD9
EEGQEPGGMEDAQGP	RECQL4	1111	O94761
SNGGSNVGMEDGERP	PRRC2A	1226	P48634
DKMENGSGGGGFFES	RAP1GAP	416	P47736
MPGDSGSEIQGSNGE	MAPKAP1	46	Q9BPZ7
FQGSGPEEMTFRGGD	SH3TC1	316	Q8TE82
DTGAMNQGGKGFGVE	MYCBP2	716	O75592
NPNNDGADGMGIFDL	MED13	1986	Q9UHV7
MDQEGGGDGQKAPSF	SETD1A	1	O15047
MEASDGQGGEGDKPL	C17orf64	1	Q86WR6
NFAPEFQVGDGIGMD	RIOK3	181	O14730
QDGEGEEGQEAMEAP	SUPT6H	151	Q7KZ85
SEGGPGSGMENGRDE	UNC80	1131	Q8N2C7
GEPAEGEQELQGSGM	SSH2	841	Q76I76
SIPESGQGGTEMDGF	RIPK3	316	Q9Y572
NQLDEGPMGEPEGSF	TLN1	1836	Q9Y490
GELFAQVPSMGEEGG	SPTB	1436	P11277
DSQDAGGFGPEDRLM	PLEC	1076	Q15149
QRMAAEGAPEDDGGG	THSD4	36	Q6ZMP0
GVFGDMAQDTGIPAD	MARS1	601	P56192
EDLESGDNGFPGDMD	TGFBR3	541	Q03167
GDNGFPGDMDEGDAS	TGFBR3	546	Q03167
RVGDAQGMFEPDGGG	SLC8A2	486	Q9UPR5