Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

CACNA1C MYH7 DSTN KIF3B BRCA2 GIT1 FEZ1 SYNM MYH7B PAFAH1B1 SYNE2 DIAPH1 GOLGA8K SKA2 DNAI7 NEB PACSIN2 AGTPBP1

9.69e-0710998718GO:0008092
GeneOntologyMolecularFunctiontubulin binding

KIF3B BRCA2 GIT1 FEZ1 PAFAH1B1 GOLGA8K SKA2 DNAI7 AGTPBP1

1.03e-04428879GO:0015631
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH7 KIF3B MYH7B DNAH5 DNAH7

1.66e-04118875GO:0003774
GeneOntologyMolecularFunctionprotein phosphatase binding

CACNA1C GIT1 VCAN AKAP11 AP3B1 ITPR1

3.13e-04210876GO:0019903
GeneOntologyMolecularFunctionATP-dependent activity

MYH7 WAPL KIF3B MYH7B HLTF CHD1 DNAH5 DNAH7 DICER1 TOP2A

3.34e-046148710GO:0140657
GeneOntologyMolecularFunctiondynein intermediate chain binding

PAFAH1B1 DNAH5 DNAH7

5.58e-0437873GO:0045505
GeneOntologyMolecularFunctiongamma-tubulin binding

BRCA2 GIT1 FEZ1

6.04e-0438873GO:0043015
GeneOntologyMolecularFunctiontranslation initiation factor binding

CACNA1C EIF3C EIF3CL

6.52e-0439873GO:0031369
GeneOntologyMolecularFunctionphosphatase binding

CACNA1C GIT1 VCAN AKAP11 AP3B1 ITPR1

1.04e-03264876GO:0019902
GeneOntologyBiologicalProcessmicrotubule-based process

KIF3B KASH5 BRCA2 GIT1 FEZ1 PAFAH1B1 SYNE2 AP3B2 DIAPH1 TLE6 GOLGA8K SKA2 IFT122 DNAI7 AP3B1 DNAH5 DNAH7 DICER1 AGTPBP1

6.66e-0810588719GO:0007017
GeneOntologyBiologicalProcessorganelle transport along microtubule

KIF3B FEZ1 PAFAH1B1 SYNE2 AP3B2 AP3B1 AGTPBP1

1.76e-0797877GO:0072384
GeneOntologyBiologicalProcessaxonal transport

KIF3B FEZ1 PAFAH1B1 AP3B2 AP3B1 AGTPBP1

7.54e-0775876GO:0098930
GeneOntologyBiologicalProcessactin filament-based process

CACNA1C MYH7 DSTN KASH5 RHPN2 MYH7B SCN2A PAFAH1B1 SYNE2 SCN9A DIAPH1 TLE6 AKAP11 NEB WASHC2A PACSIN2

1.16e-069128716GO:0030029
GeneOntologyBiologicalProcessmicrotubule-based transport

KIF3B FEZ1 PAFAH1B1 SYNE2 AP3B2 IFT122 AP3B1 DNAH5 AGTPBP1

1.22e-06253879GO:0099111
GeneOntologyBiologicalProcesstransport along microtubule

KIF3B FEZ1 PAFAH1B1 SYNE2 AP3B2 IFT122 AP3B1 AGTPBP1

1.84e-06197878GO:0010970
GeneOntologyBiologicalProcessanterograde axonal transport

KIF3B FEZ1 AP3B2 AP3B1 AGTPBP1

3.50e-0655875GO:0008089
GeneOntologyBiologicalProcessaxo-dendritic transport

KIF3B FEZ1 PAFAH1B1 AP3B2 AP3B1 AGTPBP1

3.65e-0698876GO:0008088
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

KIF3B FEZ1 PAFAH1B1 SYNE2 AP3B2 IFT122 AP3B1 AGTPBP1

4.93e-06225878GO:0030705
GeneOntologyBiologicalProcessmicrotubule-based movement

KIF3B FEZ1 PAFAH1B1 SYNE2 AP3B2 IFT122 DNAI7 AP3B1 DNAH5 DNAH7 AGTPBP1

7.09e-064938711GO:0007018
GeneOntologyBiologicalProcessprotein localization to endosome

AKAP11 LRRC7 WASHC2A PACSIN2

1.10e-0533874GO:0036010
GeneOntologyBiologicalProcessmeiotic cell cycle process

ANKRD31 KASH5 BRCA2 FBXO43 GOLGA8K CDC25C DICER1 TOP2A

1.76e-05268878GO:1903046
GeneOntologyBiologicalProcessestablishment of organelle localization

KIF3B KASH5 BRCA2 FEZ1 PAFAH1B1 SYNE2 AP3B2 TLE6 SKA2 AP3B1 AGTPBP1

1.84e-055468711GO:0051656
GeneOntologyBiologicalProcessorganelle fission

ANKRD31 WAPL KIF3B KASH5 BRCA2 FBXO43 GOLGA8K SKA2 AP3B1 CDC25C TOP2A

2.77e-055718711GO:0048285
GeneOntologyBiologicalProcesscell division

WAPL DSTN KIF3B BRCA2 GIT1 PAFAH1B1 TLE6 GOLGA8K SKA2 CDC25C DICER1 TOP2A

3.52e-056978712GO:0051301
GeneOntologyBiologicalProcessorganelle localization

KIF3B KASH5 BRCA2 FEZ1 PAFAH1B1 SYNE2 AP3B2 TLE6 GOLGA8K SKA2 AP3B1 AGTPBP1

3.82e-057038712GO:0051640
GeneOntologyBiologicalProcessactin filament-based movement

CACNA1C MYH7 MYH7B SCN2A SYNE2 SCN9A

4.65e-05153876GO:0030048
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

KIF3B KASH5 BRCA2 GIT1 PAFAH1B1 SYNE2 TLE6 GOLGA8K SKA2 DNAH5 DNAH7 DICER1

4.82e-057208712GO:0000226
GeneOntologyBiologicalProcessnuclear division

ANKRD31 WAPL KIF3B KASH5 BRCA2 FBXO43 GOLGA8K SKA2 CDC25C TOP2A

5.88e-055128710GO:0000280
GeneOntologyBiologicalProcessbrain development

AFF2 BRCA2 GIT1 FEZ1 UBE3A SCN2A PAFAH1B1 SYNE2 DIAPH1 CCDC141 DNAH5 DICER1 AGTPBP1

6.11e-058598713GO:0007420
GeneOntologyBiologicalProcessvesicle transport along microtubule

KIF3B PAFAH1B1 AP3B2 AP3B1

6.34e-0551874GO:0047496
GeneOntologyBiologicalProcesstelencephalon development

FEZ1 SCN2A PAFAH1B1 SYNE2 CCDC141 DNAH5 DICER1 AGTPBP1

8.02e-05332878GO:0021537
GeneOntologyBiologicalProcessmicrotubule sliding

PAFAH1B1 DNAI7

1.05e-044872GO:0051012
GeneOntologyBiologicalProcessmeiotic cell cycle

ANKRD31 KASH5 BRCA2 FBXO43 GOLGA8K CDC25C DICER1 TOP2A

1.16e-04350878GO:0051321
GeneOntologyBiologicalProcesshead development

AFF2 BRCA2 GIT1 FEZ1 UBE3A SCN2A PAFAH1B1 SYNE2 DIAPH1 CCDC141 DNAH5 DICER1 AGTPBP1

1.21e-049198713GO:0060322
GeneOntologyBiologicalProcessnuclear chromosome segregation

ANKRD31 WAPL KIF3B KASH5 BRCA2 GOLGA8K SKA2 TOP2A

1.30e-04356878GO:0098813
GeneOntologyBiologicalProcesscentral nervous system development

AFF2 BRCA2 GIT1 FEZ1 UBE3A VCAN SCN2A PAFAH1B1 SYNE2 DIAPH1 IFT122 CCDC141 DNAH5 DICER1 AGTPBP1

1.33e-0411978715GO:0007417
GeneOntologyBiologicalProcesschromosome segregation

ANKRD31 WAPL KIF3B KASH5 BRCA2 GOLGA8K SKA2 DICER1 TOP2A

1.51e-04465879GO:0007059
GeneOntologyBiologicalProcessmeiotic chromosome segregation

ANKRD31 KASH5 BRCA2 GOLGA8K TOP2A

1.67e-04122875GO:0045132
GeneOntologyBiologicalProcessspermatogonial cell division

TLE6 DICER1

1.74e-045872GO:0007284
GeneOntologyBiologicalProcessvesicle cytoskeletal trafficking

KIF3B PAFAH1B1 AP3B2 AP3B1

1.85e-0467874GO:0099518
GeneOntologyBiologicalProcessactin-mediated cell contraction

CACNA1C MYH7 MYH7B SCN2A SCN9A

2.02e-04127875GO:0070252
GeneOntologyBiologicalProcessmulticellular organismal movement

MYH7 SYNM DIAPH1 ITPR1

2.57e-0473874GO:0050879
GeneOntologyBiologicalProcessanterograde axonal transport of mitochondrion

FEZ1 AGTPBP1

2.61e-046872GO:0098957
GeneOntologyBiologicalProcessorganelle assembly

MYH7 KIF3B KASH5 FEZ1 PAFAH1B1 SYNE2 GOLGA8K IFT122 VPS36 NEB AP3B1 DNAH5 DNAH7 DICER1

2.77e-0411388714GO:0070925
GeneOntologyBiologicalProcesscell cycle process

ANKRD31 WAPL DSTN KIF3B KASH5 BRCA2 GIT1 PAFAH1B1 FBXO43 TLE6 GOLGA8K SKA2 CDC25C DICER1 TOP2A TPD52L1

3.10e-0414418716GO:0022402
GeneOntologyBiologicalProcessstriated muscle contraction

CACNA1C MYH7 SYNM MYH7B SCN2A SCN9A

3.14e-04217876GO:0006941
GeneOntologyBiologicalProcesspallium development

FEZ1 SCN2A PAFAH1B1 SYNE2 CCDC141 DICER1

3.55e-04222876GO:0021543
GeneOntologyBiologicalProcessclathrin-coated vesicle cargo loading

AP3B2 AP3B1

3.64e-047872GO:0035652
GeneOntologyBiologicalProcesstwitch skeletal muscle contraction

MYH7 SYNM

3.64e-047872GO:0014721
GeneOntologyBiologicalProcessclathrin-coated vesicle cargo loading, AP-3-mediated

AP3B2 AP3B1

3.64e-047872GO:0035654
GeneOntologyBiologicalProcessvoluntary skeletal muscle contraction

MYH7 SYNM

3.64e-047872GO:0003010
GeneOntologyBiologicalProcesscentrosome localization

PAFAH1B1 SYNE2 CCDC141

4.30e-0435873GO:0051642
GeneOntologyBiologicalProcessmicrotubule organizing center localization

PAFAH1B1 SYNE2 CCDC141

4.68e-0436873GO:0061842
GeneOntologyBiologicalProcessmembrane depolarization during action potential

CACNA1C SCN2A SCN9A

4.68e-0436873GO:0086010
GeneOntologyBiologicalProcesspositive regulation of endothelial cell development

AKAP11 DICER1

4.84e-048872GO:1901552
GeneOntologyBiologicalProcesspositive regulation of establishment of endothelial barrier

AKAP11 DICER1

4.84e-048872GO:1903142
GeneOntologyBiologicalProcessmeiosis I cell cycle process

ANKRD31 KASH5 BRCA2 CDC25C TOP2A

5.06e-04155875GO:0061982
GeneOntologyBiologicalProcessmeiotic nuclear division

ANKRD31 KASH5 BRCA2 FBXO43 GOLGA8K TOP2A

5.36e-04240876GO:0140013
GeneOntologyBiologicalProcessactin cytoskeleton organization

MYH7 DSTN KASH5 RHPN2 PAFAH1B1 DIAPH1 TLE6 AKAP11 NEB WASHC2A PACSIN2

5.49e-048038711GO:0030036
GeneOntologyBiologicalProcessmotor learning

GIT1 UBE3A

6.21e-049872GO:0061743
GeneOntologyBiologicalProcesscardiac muscle cell contraction

CACNA1C MYH7B SCN2A SCN9A

6.48e-0493874GO:0086003
GeneOntologyBiologicalProcesssupramolecular fiber organization

MYH7 DSTN KASH5 GIT1 RHPN2 KRT84 PAFAH1B1 DIAPH1 TLE6 GOLGA8K NEB WASHC2A

6.66e-049578712GO:0097435
GeneOntologyBiologicalProcesscardiac muscle contraction

CACNA1C MYH7 MYH7B SCN2A SCN9A

7.09e-04167875GO:0060048
GeneOntologyBiologicalProcesscerebral cortex radially oriented cell migration

PAFAH1B1 SYNE2 CCDC141

7.39e-0442873GO:0021799
GeneOntologyBiologicalProcessforebrain development

FEZ1 SCN2A PAFAH1B1 SYNE2 CCDC141 DNAH5 DICER1 AGTPBP1

1.07e-03489878GO:0030900
GeneOntologyBiologicalProcessregulation of neuron projection development

FEZ1 UBE3A PAFAH1B1 DIAPH1 GOLGA8K LRRC7 PRKCSH TIAM2 ITPR1

1.10e-03612879GO:0010975
GeneOntologyBiologicalProcesssexual reproduction

ANKRD31 DDIAS KASH5 BRCA2 UBE3A PAFAH1B1 FBXO43 TLE6 GOLGA8K AP3B1 CDC25C DICER1 TOP2A ITPR1

1.13e-0313128714GO:0019953
GeneOntologyCellularComponentsupramolecular fiber

CACNA1C MYH7 KIF3B FEZ1 SYNM MYH7B KRT84 PAFAH1B1 SYNE2 DIAPH1 GOLGA8K SKA2 DNAI7 NEB DNAH5 DNAH7 AHNAK2

8.43e-0611798917GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

CACNA1C MYH7 KIF3B FEZ1 SYNM MYH7B KRT84 PAFAH1B1 SYNE2 DIAPH1 GOLGA8K SKA2 DNAI7 NEB DNAH5 DNAH7 AHNAK2

9.21e-0611878917GO:0099081
GeneOntologyCellularComponentaxon cytoplasm

KIF3B PAFAH1B1 AP3B2 AP3B1 AGTPBP1

1.05e-0568895GO:1904115
GeneOntologyCellularComponentZ disc

CACNA1C MYH7 SYNM SYNE2 NEB AHNAK2

4.56e-05151896GO:0030018
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

KIF3B PAFAH1B1 AP3B2 DNAI7 AP3B1 DNAH5 DNAH7 AGTPBP1

6.23e-05317898GO:0032838
GeneOntologyCellularComponentI band

CACNA1C MYH7 SYNM SYNE2 NEB AHNAK2

7.72e-05166896GO:0031674
GeneOntologyCellularComponentaxon

CACNA1C KIF3B GIT1 FEZ1 SCN2A PAFAH1B1 AP3B2 SCN9A LRRC7 AP3B1 DICER1 TIAM2 AGTPBP1

9.83e-058918913GO:0030424
GeneOntologyCellularComponentneuron projection cytoplasm

KIF3B PAFAH1B1 AP3B2 AP3B1 AGTPBP1

1.08e-04110895GO:0120111
GeneOntologyCellularComponentcytoplasmic region

KIF3B PAFAH1B1 AP3B2 DNAI7 AP3B1 DNAH5 DNAH7 AGTPBP1

1.50e-04360898GO:0099568
GeneOntologyCellularComponentaxonemal dynein complex

DNAI7 DNAH5 DNAH7

1.60e-0425893GO:0005858
GeneOntologyCellularComponentmyofibril

CACNA1C MYH7 SYNM MYH7B SYNE2 NEB AHNAK2

1.66e-04273897GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

CACNA1C MYH7 SYNM MYH7B SYNE2 NEB AHNAK2

2.40e-04290897GO:0043292
GeneOntologyCellularComponentmicrotubule associated complex

KIF3B PAFAH1B1 DNAI7 DNAH5 DNAH7

6.28e-04161895GO:0005875
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex, eIF3m

EIF3C EIF3CL

6.33e-049892GO:0071541
GeneOntologyCellularComponentsarcomere

CACNA1C MYH7 SYNM SYNE2 NEB AHNAK2

6.85e-04249896GO:0030017
GeneOntologyCellularComponentinner dynein arm

DNAI7 DNAH7

7.89e-0410892GO:0036156
GeneOntologyCellularComponentspindle

WAPL KIF3B KASH5 GIT1 PAFAH1B1 DIAPH1 GOLGA8K SKA2

8.97e-04471898GO:0005819
GeneOntologyCellularComponentmicrotubule organizing center attachment site

KASH5 SYNE2

9.62e-0411892GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

KASH5 SYNE2

9.62e-0411892GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

KASH5 SYNE2

9.62e-0411892GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

KASH5 SYNE2

9.62e-0411892GO:0106094
GeneOntologyCellularComponentearly endosome

AP3B2 TLR3 MMGT1 AP3B1 WASHC2A VCAM1 PACSIN2 TPD52L1

1.03e-03481898GO:0005769
GeneOntologyCellularComponentsarcolemma

CACNA1C SYNM SCN2A VCAM1 AHNAK2

1.32e-03190895GO:0042383
GeneOntologyCellularComponentAP-3 adaptor complex

AP3B2 AP3B1

1.36e-0313892GO:0030123
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KIF3B FEZ1 SYNM KRT84 PAFAH1B1 DIAPH1 GOLGA8K SKA2 DNAI7 DNAH5 DNAH7

1.50e-038998911GO:0099513
GeneOntologyCellularComponentdynein complex

DNAI7 DNAH5 DNAH7

1.58e-0354893GO:0030286
GeneOntologyCellularComponentmicrotubule organizing center

KIF3B BRCA2 GIT1 FEZ1 PAFAH1B1 DIAPH1 AKAP11 IFT122 CCDC141 TOP2A PACSIN2

1.78e-039198911GO:0005815
GeneOntologyCellularComponentfilopodium

SYNE2 LRRC7 VCAM1 TIAM2

1.90e-03123894GO:0030175
GeneOntologyCellularComponentmicrotubule

KIF3B FEZ1 PAFAH1B1 GOLGA8K SKA2 DNAI7 DNAH5 DNAH7

1.96e-03533898GO:0005874
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex

EIF3C EIF3CL

2.07e-0316892GO:0005852
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN2A SCN9A

2.34e-0317892GO:0001518
GeneOntologyCellularComponentglutamatergic synapse

CACNA1C DSTN KIF3B GIT1 UBE3A SCN2A PAFAH1B1 LRRC7 DICER1 PACSIN2

2.46e-038178910GO:0098978
GeneOntologyCellularComponenteukaryotic 48S preinitiation complex

EIF3C EIF3CL

2.62e-0318892GO:0033290
GeneOntologyCellularComponenteukaryotic 43S preinitiation complex

EIF3C EIF3CL

2.92e-0319892GO:0016282
GeneOntologyCellularComponentlateral element

KASH5 BRCA2

2.92e-0319892GO:0000800
GeneOntologyCellularComponenttranslation preinitiation complex

EIF3C EIF3CL

3.24e-0320892GO:0070993
GeneOntologyCellularComponentcostamere

SYNM AHNAK2

3.92e-0322892GO:0043034
GeneOntologyCellularComponentgrowth cone

GIT1 FEZ1 PAFAH1B1 DICER1 TIAM2

3.96e-03245895GO:0030426
GeneOntologyCellularComponentsite of polarized growth

GIT1 FEZ1 PAFAH1B1 DICER1 TIAM2

4.54e-03253895GO:0030427
GeneOntologyCellularComponentT-tubule

CACNA1C SCN2A AHNAK2

4.67e-0379893GO:0030315
GeneOntologyCellularComponentmyosin filament

MYH7 MYH7B

5.05e-0325892GO:0032982
GeneOntologyCellularComponentcentrosome

KIF3B BRCA2 GIT1 FEZ1 PAFAH1B1 DIAPH1 AKAP11 CCDC141 PACSIN2

5.47e-03770899GO:0005813
GeneOntologyCellularComponentspindle microtubule

KIF3B PAFAH1B1 SKA2

5.92e-0386893GO:0005876
GeneOntologyCellularComponentmyosin II complex

MYH7 MYH7B

6.30e-0328892GO:0016460
GeneOntologyCellularComponentactin-based cell projection

PAFAH1B1 SYNE2 LRRC7 VCAM1 TIAM2

6.72e-03278895GO:0098858
GeneOntologyCellularComponentaxon initial segment

SCN2A LRRC7

6.75e-0329892GO:0043194
GeneOntologyCellularComponentsodium channel complex

SCN2A SCN9A

6.75e-0329892GO:0034706
DomainAP3_beta

AP3B2 AP3B1

2.25e-052892IPR026740
DomainAP3B_C

AP3B2 AP3B1

2.25e-052892IPR029390
DomainAP3B1_C

AP3B2 AP3B1

2.25e-052892PF14796
DomainEIF3C_N_dom

EIF3C EIF3CL

2.25e-052892IPR008905
DomaineIF-3c_N

EIF3C EIF3CL

2.25e-052892PF05470
DomainAP3B1_C

AP3B2 AP3B1

2.25e-052892SM01355
DomainEIF3C

EIF3C EIF3CL

2.25e-052892IPR027516
DomainAP_beta

AP3B2 AP3B1

2.22e-045892IPR026739
DomainNa_trans_cytopl

SCN2A SCN9A

3.33e-046892PF11933
DomainNa_trans_cytopl

SCN2A SCN9A

3.33e-046892IPR024583
DomainIQ

MYH7 MYH7B SCN2A SCN9A

6.06e-0481894SM00015
DomainIQ_motif_EF-hand-BS

MYH7 MYH7B SCN2A SCN9A

9.01e-0490894IPR000048
DomainNa_channel_asu

SCN2A SCN9A

9.86e-0410892IPR001696
DomainNa_trans_assoc

SCN2A SCN9A

9.86e-0410892IPR010526
DomainNa_trans_assoc

SCN2A SCN9A

9.86e-0410892PF06512
DomainIQ

MYH7 MYH7B SCN2A SCN9A

1.02e-0393894PS50096
DomainARM-type_fold

THADA WAPL AP3B2 DIAPH1 AP3B1 AGTPBP1 ITPR1

1.18e-03339897IPR016024
DomainDynein_heavy_chain_D4_dom

DNAH5 DNAH7

1.97e-0314892IPR024317
DomainDynein_HC_stalk

DNAH5 DNAH7

1.97e-0314892IPR024743
DomainDynein_heavy_dom-2

DNAH5 DNAH7

1.97e-0314892IPR013602
DomainDHC_N2

DNAH5 DNAH7

1.97e-0314892PF08393
DomainMT

DNAH5 DNAH7

1.97e-0314892PF12777
DomainAAA_8

DNAH5 DNAH7

1.97e-0314892PF12780
DomainIon_trans_dom

CACNA1C SCN2A SCN9A ITPR1

2.16e-03114894IPR005821
DomainIon_trans

CACNA1C SCN2A SCN9A ITPR1

2.16e-03114894PF00520
DomainDHC_fam

DNAH5 DNAH7

2.26e-0315892IPR026983
DomainClathrin/coatomer_adapt-like_N

AP3B2 AP3B1

2.26e-0315892IPR002553
DomainAdaptin_N

AP3B2 AP3B1

2.26e-0315892PF01602
DomainMyosin_N

MYH7 MYH7B

2.26e-0315892PF02736
DomainDynein_heavy_dom

DNAH5 DNAH7

2.26e-0315892IPR004273
DomainMyosin_N

MYH7 MYH7B

2.26e-0315892IPR004009
DomainDynein_heavy

DNAH5 DNAH7

2.26e-0315892PF03028
DomainChannel_four-helix_dom

CACNA1C SCN2A SCN9A

2.54e-0357893IPR027359
Domain-

CACNA1C SCN2A SCN9A

2.54e-03578931.20.120.350
DomainPINT

EIF3C EIF3CL

2.58e-0316892SM00088
DomainPCI_dom

EIF3C EIF3CL

2.91e-0317892IPR000717
DomainPCI

EIF3C EIF3CL

2.91e-0317892PF01399
DomainMyosin_tail_1

MYH7 MYH7B

3.27e-0318892PF01576
DomainMyosin_tail

MYH7 MYH7B

3.27e-0318892IPR002928
DomainMyosin-like_IQ_dom

MYH7 MYH7B

3.64e-0319892IPR027401
Domain-

MYH7 MYH7B

3.64e-03198924.10.270.10
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN2A SCN9A NEB

1.73e-0759138812438
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

THADA SYNM SYNE2 PANK4 MMGT1 AKAP11 CHD1 NCL IFT122 PRKCSH AP3B1 WASHC2A DICER1 SF3B2 PACSIN2 AGTPBP1 ITPR1

2.79e-071487911733957083
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ZCCHC14 WAPL WBP4 DIAPH1 MAML1 MMGT1 CHD1 WASHC2A DICER1 SF3B2 PACSIN2 AGTPBP1

4.85e-07733911234672954
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

THADA WAPL DIAPH1 MAK16 CHD1 NCL PRKCSH EIF3C GLOD4 AP3B1 DNAH5 DICER1 SF3B2 TOP2A EIF3CL

4.20e-061425911530948266
Pubmed

EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.

EIF3C EIF3CL

6.77e-06291236157221
Pubmed

Association of papillomavirus E6 proteins with either MAML1 or E6AP clusters E6 proteins by structure, function, and evolutionary relatedness.

UBE3A MAML1

6.77e-06291229281732
Pubmed

80K-H interacts with inositol 1,4,5-trisphosphate (IP3) receptors and regulates IP3-induced calcium release activity.

PRKCSH ITPR1

6.77e-06291218990696
Pubmed

Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Cav1.2 Ca2+ Channels at Excitatory Synapses.

CACNA1C LRRC7

6.77e-06291228363979
Pubmed

The Cumulative Effects of the MYH7-V878A and CACNA1C-A1594V Mutations in a Chinese Family with Hypertrophic Cardiomyopathy.

CACNA1C MYH7

6.77e-06291228866666
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

CWF19L2 WAPL NCL EIF3C SF3B2 TOP2A EIF3CL

7.48e-0627191732433965
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RC3H2 WAPL RHPN2 HLTF NCL IFT122 AP3B1 DICER1 SF3B2 ITPR1

8.01e-06650911038777146
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

KIF3B GIT1 UBE3A AKAP11 HMGCS2 CPT2

8.99e-0618391631932471
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

MYH7 DSTN PAFAH1B1 PANK4 DIAPH1 NCL PRKCSH CPT2 AP3B1 SF3B2 PACSIN2 EIF3CL TPD52L1

9.19e-061149911335446349
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

MYH7 WAPL SYNM DIAPH1 CHD1 EIF3C SF3B2 TOP2A AHNAK2

1.21e-0553891928524877
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

DSTN GIT1 SYNE2 DIAPH1 HLTF MMGT1 CHD1 NCL EIF3C GLOD4 AP3B1 SF3B2 TOP2A AHNAK2

1.82e-051415911428515276
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN9A

2.03e-05391219284629
Pubmed

Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities.

CACNA1C SVEP1

2.03e-05391227529678
Pubmed

LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration.

PAFAH1B1 SYNE2

2.03e-05391229934494
Pubmed

Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells.

CHD1 NCL

2.03e-05391234381042
Pubmed

The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform.

AP3B2 AP3B1

2.03e-05391210930456
Pubmed

Epstein-Barr virus noncoding RNAs from the extracellular vesicles of nasopharyngeal carcinoma (NPC) cells promote angiogenesis via TLR3/RIG-I-mediated VCAM-1 expression.

TLR3 VCAM1

2.03e-05391230659926
Pubmed

Germline mutations of DICER1 in Chinese women with BRCA1/BRCA2-negative familial breast cancer.

BRCA2 DICER1

2.03e-05391225526195
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

GIT1 UBE3A PAFAH1B1 PANK4 DIAPH1 NCL VPS36 PRKCSH EIF3C AP3B1 WASHC2A PACSIN2 EIF3CL AHNAK2

2.48e-051455911422863883
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

RC3H2 MYH7 WAPL BRCA2 SYNE2 HLTF NCL SF3B2 TIAM2 ITPR1

2.86e-05754911035906200
Pubmed

Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles.

MYH7 MYH7B

4.05e-05491219948655
Pubmed

Regulation of large dense-core vesicle volume and neurotransmitter content mediated by adaptor protein 3.

AP3B2 AP3B1

4.05e-05491216788073
Pubmed

Developmental expression and intracellular location of P400 protein characteristic of Purkinje cells in the mouse cerebellum.

AGTPBP1 ITPR1

4.05e-0549122707487
Pubmed

Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies.

EIF3C EIF3CL

4.05e-05491210504338
Pubmed

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.

SYNE2 TIAM2

4.05e-05491229844364
Pubmed

Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.

WAPL EIF3CL

4.05e-05491218187866
Pubmed

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.

GIT1 FEZ1 ING5 HLTF

4.62e-057591415383276
Pubmed

DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination.

DSTN HLTF GLOD4

5.41e-052891332937373
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN2A NEB

6.74e-0559121679748
Pubmed

Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.

BRCA2 HLTF

6.74e-05591229053959
Pubmed

Genetic association and post-mortem brain mRNA analysis of DISC1 and related genes in schizophrenia.

FEZ1 PAFAH1B1

6.74e-05591219632097
Pubmed

Adaptor protein-3 produces synaptic vesicles that release phasic dopamine.

AP3B2 AP3B1

6.74e-05591237812725
Pubmed

Mesenchymal dysplasia: a recessive mutation on chromosome 13 of the mouse.

AP3B1 AGTPBP1

6.74e-0559128830098
Pubmed

Association analysis between schizophrenia and the AP-3 complex genes.

AP3B2 AP3B1

6.74e-05591219481122
Pubmed

Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.

WAPL TOP2A

1.01e-04691231202577
Pubmed

Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.

AP3B2 AP3B1

1.01e-04691215537701
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN2A SCN9A

1.01e-04691223652591
Pubmed

Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging.

FEZ1 PAFAH1B1

1.01e-04691220084519
Pubmed

Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.

KASH5 SYNE2

1.01e-04691233058875
Pubmed

TRBP maintains mammalian embryonic neural stem cell properties by acting as a novel transcriptional coactivator of the Notch signaling pathway.

MAML1 DICER1

1.01e-04691228174252
Pubmed

Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates.

SF3B2 TOP2A

1.01e-04691219329795
Pubmed

Genetic predictors of depressive symptoms in cardiac patients.

CACNA1C VCAM1

1.01e-04691218618671
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

RC3H2 KIF3B WBP4 NCL EIF3C DICER1 SF3B2 PACSIN2 EIF3CL

1.19e-0472391934133714
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

WAPL KRT84 VCAN DIAPH1 CRYBG1 CPT2 AP3B1 WASHC2A PACSIN2 TIAM2 ITPR1

1.25e-041084911111544199
Pubmed

Heart neurons use clock genes to control myocyte proliferation.

CACNA1C CDC25C TOP2A

1.26e-043791334851661
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WAPL GIT1 FEZ1 KLHL7 SYNM UBE3A IFT122 EIF3C DNAI7 REPS2 SF3B2 AGTPBP1

1.31e-041285911235914814
Pubmed

Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin.

CACNA1C MYH7

1.41e-0479129004034
Pubmed

Characterization of the adaptor-related protein complex, AP-3.

AP3B2 AP3B1

1.41e-0479129151686
Pubmed

Elongator and codon bias regulate protein levels in mammalian peripheral neurons.

BRCA2 VCAN

1.41e-04791229497044
Pubmed

Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study.

BRCA2 CDC25C

1.41e-04791219626602
Pubmed

SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.

HLTF AHNAK2

1.41e-04791223415230
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

B3GALNT1 UBE3A PAFAH1B1 HMGCS2 AP3B1 SF3B2

1.52e-0430491632235678
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYNE2 DNAH7 DICER1 ARSG

1.53e-0410291410231032
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

WAPL KLHL7 DIAPH1 HLTF MAK16 CRYBG1 CHD1 NCL AP3B1 SF3B2 TOP2A EIF3CL

1.66e-041318911230463901
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

THADA KIF3B GIT1 KLHL7 PAFAH1B1 MAML1 IFT122 AP3B1 CDC25C SH3RF3 DICER1 EIF3CL

1.70e-041321911227173435
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

GIT1 FEZ1 UBE3A SYNE2 ING5 PRKCSH EIF3C GLOD4 SF3B2 TIAM2 FAM118B

1.71e-041124911121900206
Pubmed

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.

BRCA2 NEB AGTPBP1

1.85e-044291329348145
Pubmed

Increased Postnatal Cardiac Hyperplasia Precedes Cardiomyocyte Hypertrophy in a Model of Hypertrophic Cardiomyopathy.

MYH7 CDC25C

1.88e-04891228659827
Pubmed

Association of the AP-3 adaptor complex with clathrin.

AP3B2 AP3B1

1.88e-0489129545220
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

MYH7 WAPL DSTN SYNE2 NEB SVEP1

2.07e-0432291626514267
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DSTN KIF3B GIT1 KLHL7 UBE3A SYNE2 DIAPH1 GOLGA8K LRRC7 NCL

2.14e-04963911028671696
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

AFF2 MYH7B AP3B2 TLR3 DNAH5

2.23e-0420891533230847
Pubmed

Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming.

MYH7 HMGCS2 CPT2

2.27e-044591336220812
Pubmed

RhoE binds to ROCK I and inhibits downstream signaling.

RHPN2 DIAPH1

2.41e-04991212773565
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN2A SCN9A

2.41e-04991216382098
Pubmed

Molecular enzymology of carnitine transfer and transport.

PRKAB2 CPT2

2.41e-04991211257506
Pubmed

The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.

EIF3C EIF3CL

2.41e-04991224003236
Pubmed

AP-3 and Rabip4' coordinately regulate spatial distribution of lysosomes.

AP3B2 AP3B1

2.41e-04991223144738
Pubmed

The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.

EIF3C EIF3CL

2.41e-04991221292980
Pubmed

Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes.

BRCA2 HLTF

2.41e-04991228628639
Pubmed

Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.

RASGEF1A TRDMT1

2.41e-04991224478790
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

WAPL UBE3A CHD1 DICER1 TOP2A

2.44e-0421291533853758
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

UBE3A SYNE2 WBP4 MAML1 NEB AP3B1 DNAH7 AHNAK2

2.74e-0463891831182584
Pubmed

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.

EIF3C EIF3CL

3.01e-041091216286006
Pubmed

Conservation and diversity of eukaryotic translation initiation factor eIF3.

EIF3C EIF3CL

3.01e-04109128995409
Pubmed

Regulation of arrestin-3 phosphorylation by casein kinase II.

AP3B2 AP3B1

3.01e-041091211877451
Pubmed

HIV-1 Vpu inhibits accumulation of the envelope glycoprotein within clathrin-coated, Gag-containing endosomes.

AP3B2 AP3B1

3.01e-041091218076669
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

CWF19L2 BRCA2 MAML1 CHD1 AP3B1

3.02e-0422291537071664
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MYH7 GIT1 SYNE2 EIF3C NEB CCDC141 AGTPBP1

3.36e-0449791723414517
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CACNA1C WAPL SCN9A VPS36 DNAI7 NEB SH3RF3

3.36e-0449791736774506
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

VCAN SYNE2 AP3B2 NCL GLOD4 AP3B1 TOP2A

3.40e-0449891736634849
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DSTN GIT1 VCAN SCN2A PAFAH1B1 AP3B2 LRRC7 NCL EIF3C AP3B1 AGTPBP1 EIF3CL

3.52e-041431911237142655
Pubmed

Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein association.

AFF2 PRKCSH

3.67e-041191212586822
Pubmed

A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.

KASH5 SYNE2

3.67e-041191222826121
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ZCCHC14 GIT1 SYNE2 AKAP11 CDC25C DNAH7 SH3RF3 AHNAK2 TPD52L1

4.29e-0486191936931259
Pubmed

The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1.

WBP4 CDC25C

4.39e-041291211604498
Pubmed

Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3.

EIF3C EIF3CL

4.39e-041291214519125
Pubmed

Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles.

AP3B2 AP3B1

4.39e-041291219144828
Pubmed

Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.

FEZ1 PAFAH1B1

4.39e-041291219251251
Pubmed

Reconstitution reveals the functional core of mammalian eIF3.

EIF3C EIF3CL

4.39e-041291217581632
Pubmed

Jumonji, a nuclear protein that is necessary for normal heart development.

MYH7 VCAM1

4.39e-041291210807864
Pubmed

Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.

HLTF HMGCS2 ITPR1

4.58e-045791317208939
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

WAPL GIT1 UBE3A PAFAH1B1 WASHC2A AHNAK2

4.86e-0437891634315543
Pubmed

Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis.

MYH7 MYH7B

5.18e-041391224565863
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN2A SCN9A

5.18e-041391215123669
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

THADA SYNM SYNE2 PANK4 MMGT1 AKAP11 NCL PRKCSH CPT2 TOP2A AHNAK2 ITPR1

5.23e-041496911232877691
GeneFamilySodium voltage-gated channel alpha subunits

SCN2A SCN9A

3.11e-0495421203
GeneFamilyMyosin heavy chains

MYH7 MYH7B

8.97e-04155421098
GeneFamilyPDZ domain containing

RHPN2 LRRC7 TIAM2 AHNAK2

1.10e-031525441220
GeneFamilyDyneins, axonemal

DNAH5 DNAH7

1.16e-0317542536
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

AKAP11 DNAI7 CDC25C ITPR1

2.08e-03181544694
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

SYNM AKAP11

3.38e-0329542396
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

B3GALNT1 CWF19L2 UBE3A SYNE2 WBP4 HLTF AKAP11 CHD1 NCL AP3B1 AGTPBP1 ITPR1

2.52e-066569012M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

WAPL BRCA2 UBE3A PAFAH1B1 SYNE2 WBP4 HLTF AKAP11 CHD1 AP3B1 DICER1 TOP2A ITPR1

7.08e-068569013M4500
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CACNA1C AFF2 VCAN SCN2A AP3B2 PRKAB2 SCN9A LRRC7 NEB CCDC141 DICER1 AGTPBP1 AHNAK2 TPD52L1

2.37e-0511069014M39071
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

IGSF10 DDIAS AFF2 BRCA2 VCAN SYNE2 SKA2 HMGCS2 REPS2 CDC25C TOP2A SVEP1 VCAM1 TPD52L1

3.60e-067688914gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

DDIAS AFF2 KLHL7 VCAN SCN2A SYNE2 TMTC2 SKA2 HMGCS2 CDC25C DNAH7 TOP2A SVEP1 TPD52L1

8.38e-068278914gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

IGSF10 AFF2 VCAN SCN2A SYNE2 SKA2 REPS2 CDC25C CCDC141 TOP2A SVEP1 VCAM1 TPD52L1

1.95e-057738913gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

IGSF10 VCAN SYNE2 SKA2 REPS2 TOP2A SVEP1 VCAM1

4.78e-05310898gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500

IGSF10 CACNA1C DDIAS CWF19L2 AFF2 BRCA2 UBE3A MYH7B VCAN AP3B2 MAK16 SKA2 NCL CDC25C TOP2A VCAM1 TPD52L1

1.11e-0414688917facebase_RNAseq_e10.5_MandArch_2500
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B3GALNT1 CACNA1C THADA AFF2 FEZ1 HMGCS2 SVEP1

1.33e-07191917b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TLE6 SKA2 NEB CDC25C TOP2A EIF3CL

9.91e-071619162165897924c790fec43502283f1df221c56c1e9f
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

B3GALNT1 BRCA2 GIT1 FBXO43 CDC25C TOP2A

1.61e-061759160b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL PAFAH1B1 SYNE2 DIAPH1 CHD1 NCL

2.37e-06187916663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 FBXO43 SKA2 CDC25C TOP2A SVEP1

2.37e-06187916e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 FBXO43 SKA2 CDC25C TOP2A SVEP1

2.37e-06187916cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IGSF10 CACNA1C VCAN TMTC2 SVEP1 VCAM1

3.19e-061979160034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VCAN SYNE2 TMTC2 TOP2A SVEP1 VCAM1

3.39e-0619991601ab0363558f215f9979e20fd5170d8fee149cea
ToppCellLeuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, Lineage and Cell Type

B3GALNT1 IGSF10 TLR3 SCN9A HLTF

2.00e-0516191551b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|COVID-19_Mild / Disease condition and Cell class

WAPL VCAN EIF3C WASHC2A EIF3CL

2.25e-05165915ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 FBXO43 SKA2 CDC25C TOP2A

2.38e-0516791550c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 FBXO43 SKA2 CDC25C TOP2A

2.45e-05168915d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|Classical_Monocyte / Disease condition and Cell class

WAPL SYNE2 EIF3C WASHC2A EIF3CL

2.45e-05168915d50078614f7af74dc2aa4081c1708a5156ac51cf
ToppCellDividing_Macrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

BRCA2 FBXO43 SKA2 CDC25C TOP2A

2.52e-05169915eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 FBXO43 SKA2 CDC25C TOP2A

2.52e-05169915b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

BRCA2 FBXO43 LRRC7 CDC25C TOP2A

2.67e-051719154ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCelldroplet-Marrow-BM_(NON-STC)|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL DSTN VCAN UBAC1 TOP2A

2.75e-051729156004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

CACNA1C AFF2 FEZ1 SYNM SH3RF3

2.75e-05172915858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCelldroplet-Marrow-BM_(NON-STC)-30m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL DSTN VCAN UBAC1 TOP2A

2.75e-0517291531c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DDIAS BRCA2 FBXO43 CDC25C TOP2A

2.90e-05174915dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|356C / Donor, Lineage, Cell class and subclass (all cells)

BRCA2 IFT122 CDC25C SH3RF3 TOP2A

3.07e-051769154bba41ebf9dd187c8705a6997ed039878de62b4e
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSTN AFF2 SYNE2 TOP2A VCAM1

3.24e-0517891515a99080e9f669572ab6d82934f324e6714846c1
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSTN AFF2 SYNE2 TOP2A VCAM1

3.24e-05178915200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 SCN2A FBXO43 CDC25C TOP2A

3.41e-05180915401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRCA2 FBXO43 SKA2 CDC25C TOP2A

3.50e-0518191573b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSTN AFF2 SYNE2 TOP2A VCAM1

3.50e-05181915566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SCN2A CRYBG1 TMTC2 HMGCS2 REPS2

3.50e-05181915b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSTN AFF2 SYNE2 TOP2A VCAM1

3.50e-05181915db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

KASH5 BRCA2 SKA2 CDC25C TOP2A

3.69e-05183915a48a6313f2f144586951cece97ec31f6d72361df
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

BRCA2 GIT1 FBXO43 CDC25C TOP2A

3.69e-05183915a716b446c2bf5aa294b8f580aa845098fae76354
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

CACNA1C MYH7 MYH7B CCDC141 TPD52L1

3.79e-05184915ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 FBXO43 SKA2 CDC25C TOP2A

3.89e-0518591530e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

CACNA1C MYH7 MYH7B CCDC141 TPD52L1

3.89e-051859156baccb26f999145e51b91d94315bf8d4655bef31
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNE2 CRYBG1 CHD1 AGTPBP1 EIF3CL

4.09e-05187915e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DDIAS BRCA2 FBXO43 CDC25C TOP2A

4.09e-0518791573931a5ea73799095daff100b5f18853c57c74dc
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CACNA1C DSTN C8orf34 PACSIN2 ITPR1

4.20e-0518891534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TLR3 LRRC7 DNAH7 SVEP1 TIAM2

4.20e-05188915c9270517e6940e9793586f67f02431210552f278
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

DSTN TMTC2 CCDC141 DNAH5 C8orf34

4.20e-05188915707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C FEZ1 SVEP1 VCAM1

4.31e-05189915a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C FEZ1 SVEP1 VCAM1

4.31e-05189915e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

CACNA1C MYH7 KLHL7 MYH7B CCDC141

4.31e-051899155e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SCN2A CRYBG1 TMTC2 HMGCS2 REPS2

4.31e-05189915c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCN2A CRYBG1 TMTC2 HMGCS2 REPS2

4.31e-05189915fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDR1 VCAN SCN9A RASGEF1A ITPR1

4.31e-05189915fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

CACNA1C MYH7 KLHL7 MYH7B CCDC141

4.41e-05190915de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CACNA1C VCAN TMTC2 REPS2 C8orf34

4.41e-051909157986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

CACNA1C MYH7 KLHL7 MYH7B CCDC141

4.41e-05190915fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C FEZ1 SVEP1 VCAM1

4.41e-05190915841cd55861b43578d704418b9bc0af2e8b88323a
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL SYNE2 DIAPH1 AKAP11 EIF3C

4.53e-0519191560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C VCAN SVEP1 VCAM1

4.53e-05191915b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

CACNA1C MYH7 KLHL7 MYH7B CCDC141

4.53e-0519191525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

DNAI7 DNAH5 C8orf34 DNAH7 AHNAK2

4.53e-05191915ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FEZ1 VCAN LRRC7 SVEP1 VCAM1

4.53e-0519191589d03c4133dda852a3713c0902a7d67941cf5b21
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL SYNE2 DIAPH1 AKAP11 EIF3C

4.53e-0519191509db184cb90fe282a14474d7217068c58092c6f8
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

DNAI7 DNAH5 C8orf34 DNAH7 AHNAK2

4.53e-051919156228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL SYNE2 DIAPH1 AKAP11 EIF3C

4.53e-05191915973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

SCN2A CRYBG1 TMTC2 TPD52L1 ITPR1

4.64e-05192915d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C FEZ1 SVEP1 VCAM1

4.64e-05192915f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF10 VCAN HMGCS2 SVEP1 VCAM1

4.64e-051929157b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C FEZ1 SVEP1 VCAM1

4.64e-05192915dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF10 VCAN HMGCS2 SVEP1 VCAM1

4.64e-0519291532acd89617934016cd135d2cc797e8e79ae1b37f
ToppCellControl-Lymphoid-Proliferating_CD4_T_cells|Control / Condition, Lineage and Cell class

BRCA2 FBXO43 SKA2 CDC25C TOP2A

4.76e-0519391533d409d6ed1c606337248587ad997ac5f67f081d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DDIAS BRCA2 MMGT1 CDC25C TOP2A

4.87e-05194915590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C LRRC7 SVEP1 VCAM1

4.87e-0519491589b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE2 DNAI7 DNAH5 C8orf34 DNAH7

4.99e-05195915fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SYNE2 DNAI7 DNAH5 C8orf34 DNAH7

4.99e-0519591521dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE2 DNAI7 DNAH5 C8orf34 DNAH7

4.99e-05195915eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellControl-Lymphoid-Proliferating_CD4_T_cells|Lymphoid / Condition, Lineage and Cell class

BRCA2 VCAN FBXO43 CDC25C TOP2A

4.99e-05195915578bbb06a5476c08fc3b351cc580c551dfe53ae4
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF10 WAPL AFF2 CHD1 NEB

4.99e-051959155c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF10 FEZ1 VCAN SVEP1 VCAM1

5.12e-05196915d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

CACNA1C BRCA2 FBXO43 CDC25C TOP2A

5.12e-051969152ce8a787f2731faa913d20342d73041d59468f27
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE2 DNAH5 C8orf34 DNAH7 TOP2A

5.12e-05196915af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE2 DNAH5 C8orf34 DNAH7 TOP2A

5.12e-051969156d02d494196e3f857d53eea46d9419690d43beca
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

RHPN2 DNAI7 DNAH5 C8orf34 DNAH7

5.12e-0519691587d9881cfec461a5d89b688a83749b618c519485
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

IGSF10 LRRC7 DNAI7 SVEP1 VCAM1

5.24e-05197915fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DDIAS BRCA2 FBXO43 CDC25C TOP2A

5.24e-0519791584ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHPN2 SCN2A SYNE2 REPS2 DNAH7

5.24e-051979157e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE2 DNAI7 DNAH5 C8orf34 DNAH7

5.24e-0519791574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRCA2 SKA2 CDC25C TOP2A VCAM1

5.24e-0519791576b61e60a757e58b465569538e632d6d9953e89a
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FBXO43 DNAI7 DNAH5 DNAH7 TOP2A

5.24e-051979156e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1C VCAN TMTC2 SVEP1 VCAM1

5.24e-0519791511a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C UBE3A SCN2A LRRC7 ITPR1

5.37e-05198915c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMTC2 REPS2 CCDC141 C8orf34 PACSIN2

5.50e-051999155cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellSepsis-Leuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, condition lineage and cell class

B3GALNT1 IGSF10 TLR3 SCN9A HLTF

5.50e-05199915a2f154b15087803958a656d2a41b6d83fd37b32f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 FBXO43 SKA2 CDC25C TOP2A

5.50e-051999154af38f5e9d2229d64f7ecdf9c00b4d67e5f86a51
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DDIAS BRCA2 SYNE2 CDC25C TOP2A

5.50e-05199915be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell(2)_Fibroblasts-(24)_Fibro-5|World / Cell class and subclass of bone marrow stroma cells in homeostatis

DSTN FEZ1 SYNM VCAN AHNAK2

5.50e-051999156c0354f57883330c685a8d9d5d3014ace7eca584
ToppCelldistal-Hematologic-Proliferating_Macrophage|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRCA2 FBXO43 SKA2 CDC25C TOP2A

5.63e-052009153835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCelldistal-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRCA2 FBXO43 SKA2 CDC25C TOP2A

5.63e-052009150cd3b01fb7f579e5abf000adb8ec8adc7cd779c4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 FBXO43 SKA2 CDC25C TOP2A

5.63e-0520091528c702449040ac15fe4e0c6340bb6f137e88539d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

AFF2 GIT1 PRKAB2 CPT2 DNAH7

5.63e-052009156b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellLAM-Myeloid-pMacrophage|LAM / Condition, Lineage and Cell class

BRCA2 FBXO43 SKA2 CDC25C TOP2A

5.63e-052009157e233d037165c9d3607604aaaf0f368e266567d3
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

SYNE2 DIAPH1 GOLGA8R EIF3C EIF3CL

5.63e-052009152281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-Dividing_AT2|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD31 SCN9A MAK16 DNAH5 TOP2A

5.63e-05200915befc25cbcbac2c02e5fd33d6e78e59979050090c
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF2 SYNM HMGCS2 REPS2

9.12e-05115914ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF2 SYNM HMGCS2 REPS2

9.12e-051159147a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF2 SYNM HMGCS2 REPS2

9.12e-05115914c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4|E18.5-samps / Age Group, Lineage, Cell class and subclass

DDIAS SKA2 CDC25C TOP2A

1.46e-04130914169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCellLV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CACNA1C MYH7 MYH7B CCDC141

1.46e-04130914a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WAPL EIF3C WASHC2A EIF3CL

2.11e-04143914bd3f5fbd4e9e4dc414682db5607494f3ce988deb
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

MYH7 SYNE2

1.71e-047852C0751337
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN2A SCN9A

2.91e-049852C3502809
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH7 MYH7B

3.64e-0410852DOID:0110454 (implicated_via_orthology)
DiseaseAnemia, Sickle Cell

CACNA1C VCAM1

3.64e-0410852C0002895
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH7 MYH7B

3.64e-0410852DOID:0111269 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN2A SCN9A

3.64e-0410852DOID:0111294 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH7 MYH7B

3.64e-0410852DOID:0080719 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN2A SCN9A

3.64e-0410852DOID:0080422 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH7 MYH7B

3.64e-0410852DOID:0111602 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH7 MYH7B

3.64e-0410852DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH7 MYH7B

3.64e-0410852DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH7 MYH7B

3.64e-0410852DOID:0080326 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH7 MYH7B

3.64e-0410852DOID:0111596 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH7 MYH7B

5.31e-0412852DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH7 MYH7B

5.31e-0412852DOID:2106 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN2A SCN9A

5.31e-0412852DOID:0060170 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH7 MYH7B

6.27e-0413852DOID:397 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

SCN2A SCN9A

6.27e-0413852C0751122
DiseaseLeft ventricular noncompaction

MYH7 MYH7B

7.30e-0414852C1960469
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH7 MYH7B

8.40e-0415852DOID:0050646 (implicated_via_orthology)
DiseaseInherited oocyte maturation defect

FBXO43 TLE6

9.59e-0416852cv:CN238505
Diseasesphingomyelin 14:0 measurement

THADA SYNE2

1.08e-0317852EFO_0010390
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH7 MYH7B DICER1

1.62e-0380853DOID:12930 (implicated_via_orthology)
Diseasehypertrophic cardiomyopathy (is_implicated_in)

MYH7 MYH7B

1.82e-0322852DOID:11984 (is_implicated_in)
Diseaseanxiety disorder (implicated_via_orthology)

SCN2A SCN9A

1.82e-0322852DOID:2030 (implicated_via_orthology)
Diseaseunipolar depression, schizophrenia

ZCCHC14 CACNA1C

2.36e-0325852EFO_0003761, MONDO_0005090
Diseasepsychosis predisposition measurement

CACNA1C CCDC141

2.55e-0326852EFO_0008337

Protein segments in the cluster

PeptideGeneStartEntry
LDMVRTIFDDKSADK

FAM200B

176

P0CF97
AEAKALDDMFESSTL

VCAN

2711

P13611
SMLEDDLKLSSDEDD

AFF2

421

P51816
ALMEEGDEFEKASKL

C8orf34

451

Q49A92
EVFDALKLDSMESSE

PRKAB2

161

O43741
MEKASSEERCKSLFD

AKAP11

1881

Q9UKA4
AETKDTANLDKMASE

ARSG

56

Q96EG1
MADSLDLSELAKAAK

GIT1

251

Q9Y2X7
LTMSSLFNKEDEDKL

C1orf232

66

A0A0U1RR37
DASFETKESRKEELM

DSTN

86

P60981
EDAKKEMASLSAAAI

DIAPH1

556

O60610
IMLADTDKIKSFEED

DICER1

561

Q9UPY3
DIDFKFMEDIEKSEA

DICER1

891

Q9UPY3
DEGEKKSTFMDLAKE

AGTPBP1

486

Q9UPW5
KSTFMDLAKEDIKDN

AGTPBP1

491

Q9UPW5
SYKEDEEMKTDSDDL

CHD1

241

O14646
KDFLEDMDSLEDLEA

CDR1

121

P51861
DMVRTIFDDKSADKL

FAM200A

91

Q8TCP9
DVLRKMAKSFTSEDD

AP3B1

516

O00203
DVLRKMAKSFTAEED

AP3B2

521

Q13367
EKALEDMFDALEGKS

CPT2

641

P23786
KRDEDSSLMQLKEEF

RC3H2

256

Q9HBD1
MELESKLNEAKEEFT

PAFAH1B1

66

P43034
KSEFKLELDDVTSNM

MYH7

1221

P12883
QFAKAMDEELEDLKT

KASH5

216

Q8N6L0
SALDEADDEKMKELL

ANKRD31

1256

Q8N7Z5
DMKDLFNEDFEEKKD

MAML1

266

Q92585
KKDVDAAFMNKSDLE

KRT84

271

Q9NSB2
MEALEGLDFETAKKA

IFT122

651

Q9HBG6
ISDFEDMDKLDASSD

MAK16

231

Q9BXY0
ATADKAKDDLEMSAV

ITPR1

1956

Q14643
RMTVAFEFEDKKEDD

LRRC7

456

Q96NW7
GSKLLDDAMAADKSD

GLOD4

286

Q9HC38
KFEEAERSLKDMEES

PRKCSH

376

P14314
DILEKDHFDSDDMKL

KIAA2026

886

Q5HYC2
EAEKEDKMLALSLED

B3GALNT1

121

O75752
DLDKALLKASQDMFD

HMGCS2

351

P54868
DDTFMDSRKATEKLL

MYH7B

781

A7E2Y1
SMEIFQSKLEDAEKA

CWF19L2

261

Q2TBE0
SADLFDDIAKEMDIA

DDIAS

676

Q8IXT1
FKSMEDLVNEFDEKL

FEZ1

56

Q99689
NMLESKSFEVELKDA

KLHL7

76

Q8IXQ5
SDELMEFSLKDQEAK

CDC25C

191

P30307
DFNSEEDAKAAKEAM

NCL

616

P19338
TADQEFSKEDMAKSL

PANK4

281

Q9NVE7
MSFKDKDERISCLEA

FBXO43

1

Q4G163
SFKAGDELTKMEDED

PACSIN2

446

Q9UNF0
FLKKMDDEDEDSEDS

EIF3C

211

Q99613
FLKKMDDEDEDSEDS

EIF3CL

211

B5ME19
DKSGKLELQMADSFD

IGSF10

531

Q6WRI0
SSFMDHLKEKADLSE

GOLGA8K

456

D6RF30
AMRDEINELKDSFKD

CCDC141

901

Q6ZP82
ELDKAMKEAVSAASE

CACNA1C

1726

Q13936
AKAFMEDDELTDSKL

BRCA2

2231

P51587
DCFMDDFADEVKLKE

DNAH7

1821

Q8WXX0
MASKAIKDECDADLA

DNAH7

2656

Q8WXX0
KDFASEEAMEKVRSS

DNAI7

681

Q6TDU7
DADLARFEADLKDKM

ING5

101

Q8WYH8
FDDLESKMEDSGKQL

FAM118B

131

Q9BPY3
SSELKYSMELDEKDE

FAM47A

651

Q5JRC9
VSEDDFSKLQLKESM

LAS2

326

Q8IYD9
EFKDMDATSELKNKT

MMGT1

66

Q8N4V1
KLFEDLKEDDKTHEM

HLTF

216

Q14527
TKFSELSKLKNDDME

CRYBG1

946

Q9Y4K1
SSFMDHLKEKADLSE

GOLGA8R

456

I6L899
DEINSDLASVMKKEF

DNAH5

3046

Q8TE73
EFLEDTDMKSLENKS

VCAM1

451

P19320
KEHDSFDMKDLNASV

THADA

1011

Q6YHU6
SDLSVKMLKDFLEDD

TRDMT1

246

O14717
DKLELMFQKAESDLD

SKA2

6

Q8WVK7
SAMKEAFKAQETEAE

SYNE2

3341

Q8WXH0
EEKMFDSKEKASEER

SYNM

521

O15061
DRDDDLLNKKDMAFD

SCN9A

1921

Q15858
AARCDDTDLMKKFSE

SVEP1

806

Q4LDE5
SMICLAIDDDDKTDK

RHPN2

616

Q8IUC4
EEDMSLADKDLTTKD

AHNAK2

1476

Q8IVF2
EKEDFSDMVAEHAAK

SF3B2

856

Q13435
SMEKEDQSLKFCLEE

TLR3

776

O15455
DEKEKAACSAAAMEE

UBE3A

191

Q05086
DKNISEAFEDLSKLM

VPS36

171

Q86VN1
DFQDEKAMAELKAIT

RASGEF1A

131

Q8N9B8
DLDLKQMEALFSEKS

TIAM2

951

Q8IVF5
LTTEKNSFKRMDDED

REPS2

166

Q8NFH8
KSKIMNRAFFDEEED

KIF3B

596

O15066
DFEMKDKDQDKDCLT

SH3RF3

266

Q8TEJ3
AEMAKKAAELDSTEF

TMTC2

731

Q8N394
EFSSESDMEESKEKL

SCN2A

1121

Q99250
KEEEKASKEFAAMEA

WBP4

56

O75554
DSDPLLEMKDDDFKN

WAPL

256

Q7Z5K2
DFSSMLSEEEKEELK

TPD52L1

26

Q16890
ATKTKFTMDLDSDED

TOP2A

1321

P11388
SMEKFLSLTEEDLNK

ZCCHC14

321

Q8WYQ9
EAKSIFDDDMDDIFS

WASHC2A

1286

Q641Q2
SFDEAAKIMEDLLSS

TTC37

401

Q6PGP7
LFKKANAMLDEDEDE

UBAC1

176

Q9BSL1
KDKTLQESSFEDIMA

TLE6

111

Q9H808
ESKMKDYDLRADAIS

NEB

3736

P20929