Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription coregulator activity	SMARCC2 CHD4 BRD8 CBX4 PSIP1 MIDEAS HDGF	1.23e-05	562	29	7	GO:0003712
GeneOntologyMolecularFunction	chromatin binding	SMARCC2 NR1H2 CHD4 CBX4 PSIP1 UBTF DNMT1	7.07e-05	739	29	7	GO:0003682
GeneOntologyMolecularFunction	transcription factor binding	NR1H2 CHD4 BRD8 PSIP1 TP53BP2 DNMT1 HDGF	7.96e-05	753	29	7	GO:0008134
GeneOntologyMolecularFunction	molecular adaptor activity	SMARCC2 ZC3H18 CHD4 BRD8 CBX4 AKAP9 PSIP1 MIDEAS HDGF	8.64e-05	1356	29	9	GO:0060090
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	NR1H2 CHD4 BRD8 PSIP1 TP53BP2 DNMT1	1.60e-04	582	29	6	GO:0140297
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	SMARCC2 ZC3H18 CHD4 BRD8 CBX4 PSIP1 MIDEAS HDGF	1.81e-04	1160	29	8	GO:0030674
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	NR1H2 CHD4 BRD8 TP53BP2 DNMT1	3.05e-04	417	29	5	GO:0061629
GeneOntologyMolecularFunction	transcription corepressor activity	CHD4 CBX4 MIDEAS HDGF	3.19e-04	229	29	4	GO:0003714
GeneOntologyMolecularFunction	histone binding	SMARCC2 NCL CHD4 CBX4	5.55e-04	265	29	4	GO:0042393
GeneOntologyMolecularFunction	chromatin DNA binding	SMARCC2 NR1H2 CHD4	1.79e-03	167	29	3	GO:0031490
GeneOntologyMolecularFunction	nuclear receptor binding	NR1H2 BRD8 DNMT1	2.47e-03	187	29	3	GO:0016922
GeneOntologyMolecularFunction	nuclear receptor activity	NR1H2 PDE3A	3.42e-03	60	29	2	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	NR1H2 PDE3A	3.53e-03	61	29	2	GO:0098531
GeneOntologyMolecularFunction	nucleosomal DNA binding	SMARCC2 CHD4	4.25e-03	67	29	2	GO:0031492
GeneOntologyBiologicalProcess	protein-DNA complex organization	SMARCC2 CHD4 BRD8 CBX4 GNAS PSIP1 UBN2 UBTF DNMT1 HDGF	5.86e-07	999	29	10	GO:0071824
GeneOntologyBiologicalProcess	chromatin organization	SMARCC2 CHD4 BRD8 CBX4 GNAS PSIP1 UBN2 DNMT1 HDGF	2.42e-06	896	29	9	GO:0006325
GeneOntologyCellularComponent	histone deacetylase complex	CHD4 BRD8 MIDEAS	2.43e-04	85	30	3	GO:0000118
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	SMARCC2 CHD4 BRD8	3.48e-04	96	30	3	GO:0070603
GeneOntologyCellularComponent	ATPase complex	SMARCC2 CHD4 BRD8	8.25e-04	129	30	3	GO:1904949
Domain	CHROMO	SMARCC2 CHD4 CBX4	1.98e-05	33	30	3	SM00298
Domain	Chromo/shadow_dom	SMARCC2 CHD4 CBX4	1.98e-05	33	30	3	IPR000953
Domain	PWWP	PSIP1 HDGF	4.65e-04	20	30	2	SM00293
Domain	PWWP	PSIP1 HDGF	6.18e-04	23	30	2	PF00855
Domain	PWWP_dom	PSIP1 HDGF	6.18e-04	23	30	2	IPR000313
Domain	PWWP	PSIP1 HDGF	6.73e-04	24	30	2	PS50812
Domain	Chromo_domain	CHD4 CBX4	6.73e-04	24	30	2	IPR023780
Domain	Chromo	CHD4 CBX4	7.91e-04	26	30	2	PF00385
Domain	SANT_dom	SMARCC2 MIDEAS	7.91e-04	26	30	2	IPR017884
Domain	CHROMO_2	CHD4 CBX4	9.19e-04	28	30	2	PS50013
Domain	CHROMO_1	CHD4 CBX4	9.19e-04	28	30	2	PS00598
Domain	SANT	SMARCC2 MIDEAS	9.19e-04	28	30	2	PS51293
Domain	Chromodomain-like	CHD4 CBX4	1.20e-03	32	30	2	IPR016197
Domain	Myb_DNA-binding	SMARCC2 MIDEAS	1.44e-03	35	30	2	PF00249
Domain	MYB_LIKE	SMARCC2 MIDEAS	1.69e-03	38	30	2	PS50090
Domain	-	PPP1R10 ZC3H18	1.87e-03	40	30	2	4.10.1000.10
Domain	ZnF_C3H1	PPP1R10 ZC3H18	2.69e-03	48	30	2	SM00356
Domain	SANT	SMARCC2 MIDEAS	2.91e-03	50	30	2	SM00717
Domain	SANT/Myb	SMARCC2 MIDEAS	3.15e-03	52	30	2	IPR001005
Domain	Znf_CCCH	PPP1R10 ZC3H18	3.90e-03	58	30	2	IPR000571
Domain	ZF_C3H1	PPP1R10 ZC3H18	3.90e-03	58	30	2	PS50103
Domain	HMG_box_dom	CHD4 UBTF	4.87e-03	65	30	2	IPR009071
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	SMARCC2 NR1H2 CHD4 CBX4 PSIP1 ZNF688 UBTF TP53BP2 DNMT1	1.72e-05	1022	23	9	MM15436
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	SMARCC2 CHD4 PSIP1 UBTF DNMT1	4.71e-05	254	23	5	M27131
Pathway	WP_NOCGMPPKG_MEDIATED_NEUROPROTECTION	PDE3A AKAP9 CNGB3	5.87e-05	47	23	3	M39531
Pathway	PID_RB_1PATHWAY	CBX4 UBTF DNMT1	1.55e-04	65	23	3	M279
Pathway	REACTOME_SUMOYLATION_OF_DNA_METHYLATION_PROTEINS	CBX4 DNMT1	3.01e-04	16	23	2	M27403
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SMARCC2 PPP1R10 NCL ZC3H18 CHD4 BRD8 CBX4 PSIP1 UBN2 MIDEAS UBTF PRRC2C AHNAK DNMT1	1.20e-14	954	30	14	36373674
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SMARCC2 PPP1R10 ZC3H18 CHD4 CBX4 PSIP1 UBN2 MIDEAS UBTF DNMT1 HDGF	1.72e-12	608	30	11	36089195
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PPP1R10 NCL ZC3H18 CHD4 BRD8 CBX4 PSIP1 UBN2 MIDEAS UBTF AHNAK DNMT1 AFG3L2	1.64e-11	1294	30	13	30804502
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	SMARCC2 PPP1R10 NCL ZC3H18 CHD4 BRD8 CBX4 PSIP1 UBTF AHNAK DNMT1 HDGF	1.89e-11	1014	30	12	32416067
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	SMARCC2 PPP1R10 ZC3H18 PSIP1 UBTF PRRC2C AHNAK DNMT1 AFG3L2	1.52e-10	469	30	9	27634302
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SMARCC2 PPP1R10 NCL CHD4 GNAS AKAP9 PSIP1 MIDEAS PRRC2C AHNAK LAD1 DNMT1	6.01e-10	1371	30	12	36244648
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	PPP1R10 NCL CHD4 PSIP1 UBTF PRRC2C AHNAK TP53BP2 DNMT1 AFG3L2	3.43e-09	934	30	10	33916271
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PPP1R10 NCL ZC3H18 GNAS PSIP1 UBTF PRRC2C AHNAK LAD1 DNMT1 AFG3L2	3.82e-09	1257	30	11	36526897
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	SMARCC2 PPP1R10 NCL CHD4 PSIP1 MIDEAS AHNAK	1.35e-08	340	30	7	24332808
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	PPP1R10 BRD8 UBN2 MIDEAS PRRC2C AHNAK TP53BP2 DNMT1	1.58e-08	549	30	8	38280479
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	SMARCC2 PPP1R10 NCL GNAS MIDEAS UBTF PRRC2C TP53BP2	3.79e-08	615	30	8	31048545
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	PPP1R10 BRD8 CBX4 UBN2 AHNAK TP53BP2 AFG3L2 HDGF	5.47e-08	645	30	8	25281560
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	NCL CHD4 PSIP1 MIDEAS UBTF AHNAK	5.92e-08	245	30	6	21182205
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SMARCC2 NCL ZC3H18 CHD4 UBTF PRRC2C AHNAK DNMT1	6.02e-08	653	30	8	22586326
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	PPP1R10 NCL ZC3H18 CHD4 PRRC2C AHNAK	6.84e-08	251	30	6	31076518
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	SMARCC2 NCL PDE3A GNAS PSIP1 PRRC2C AHNAK DNMT1 PNPO AFG3L2	7.64e-08	1297	30	10	33545068
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	SMARCC2 PPP1R10 NCL CHD4 MIDEAS UBTF AHNAK DNMT1 HDGF	9.80e-08	989	30	9	36424410
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SMARCC2 PPP1R10 NCL CHD4 GNAS PSIP1 UBTF AHNAK AFG3L2	1.32e-07	1024	30	9	24711643
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	PPP1R10 NCL ZC3H18 CHD4 MIDEAS	1.71e-07	148	30	5	32538781
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SMARCC2 NCL ZC3H18 CHD4 PSIP1 PRRC2C AHNAK DNMT1 AFG3L2 HDGF	1.72e-07	1415	30	10	28515276
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	SMARCC2 CHD4 PSIP1 UBN2 MIDEAS UBTF PRRC2C DNMT1 HDGF	2.47e-07	1103	30	9	34189442
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	SMARCC2 ZC3H18 CHD4 CBX4 PSIP1 UBTF DNMT1	2.86e-07	533	30	7	30554943
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	NCL CHD4 PRRC2C AHNAK TP53BP2 DNMT1	3.54e-07	332	30	6	37433992
Pubmed	TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.	SMARCC2 CHD4 DNMT1	4.68e-07	18	30	3	28068325
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CBX4 HIVEP2 GNAS AKAP9 PRRC2C AHNAK TP53BP2 DNMT1	4.93e-07	861	30	8	36931259
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SMARCC2 PPP1R10 NCL CHD4 CBX4 GNAS PSIP1 AHNAK AFG3L2	5.11e-07	1203	30	9	29180619
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ZC3H18 CBX4 GPBP1L1 GNAS UBN2 PRRC2C AFG3L2	5.53e-07	588	30	7	38580884
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	SMARCC2 NCL CHD4 UBTF AHNAK DNMT1 AFG3L2	6.41e-07	601	30	7	33658012
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	SMARCC2 NCL CHD4 CBX4 UBTF	6.69e-07	195	30	5	19454010
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	SMARCC2 NCL ZC3H18 CHD4 PSIP1 UBTF PRRC2C	6.70e-07	605	30	7	28977666
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	SMARCC2 NCL CHD4 GNAS AKAP9 TP53BP2 LAD1 AFG3L2 HDGF	6.89e-07	1247	30	9	27684187
Pubmed	Hepatoma-derived growth factor and nucleolin exist in the same ribonucleoprotein complex.	NCL HDGF	7.19e-07	2	30	2	23305559
Pubmed	A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis.	NCL DNMT1	7.19e-07	2	30	2	25015109
Pubmed	Hepatoma-derived growth factor/nucleolin axis as a novel oncogenic pathway in liver carcinogenesis.	NCL HDGF	7.19e-07	2	30	2	25938538
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	SMARCC2 PPP1R10 CHD4 AHNAK HDGF	8.16e-07	203	30	5	22083510
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	SMARCC2 NCL PSIP1 PRRC2C AHNAK HDGF	1.03e-06	399	30	6	35987950
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	NCL ZC3H18 CHD4 GNAS MIDEAS UBTF PRRC2C	1.14e-06	655	30	7	35819319
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SMARCC2 NCL CHD4 AKAP9 UBN2 PRRC2C TP53BP2 DNMT1	1.14e-06	963	30	8	28671696
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	PPP1R10 NCL ZC3H18 CHD4 GNAS PRRC2C DNMT1	1.26e-06	665	30	7	30457570
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SMARCC2 NCL CHD4 MIDEAS UBTF AHNAK TP53BP2 DNMT1 AFG3L2	1.36e-06	1353	30	9	29467282
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	SMARCC2 BRD8 PSIP1 UBN2 UBTF HDGF	1.49e-06	425	30	6	24999758
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SMARCC2 PDE3A PSIP1 UBTF AHNAK	1.64e-06	234	30	5	36243803
Pubmed	Nucleolar localization of the ErbB3 receptor as a new target in glioblastoma.	NCL UBTF	2.16e-06	3	30	2	35255831
Pubmed	Nucleolar localization of aprataxin is dependent on interaction with nucleolin and on active ribosomal DNA transcription.	NCL UBTF	2.16e-06	3	30	2	16777843
Pubmed	Two new isoforms of the human hepatoma-derived growth factor interact with components of the cytoskeleton.	NCL HDGF	2.16e-06	3	30	2	26845719
Pubmed	FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.	CHD4 PSIP1 UBTF DNMT1 HDGF	2.18e-06	248	30	5	27926873
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	SMARCC2 CHD4 BRD8 UBN2 MIDEAS	3.19e-06	268	30	5	33640491
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	SMARCC2 NCL UBTF PRRC2C DNMT1 AFG3L2	3.23e-06	486	30	6	30940648
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SMARCC2 NCL ZC3H18 CHD4 BRD8 PSIP1 DNMT1	3.43e-06	774	30	7	15302935
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	PPP1R10 NCL ZC3H18 PSIP1 DNMT1	4.15e-06	283	30	5	30585729
Pubmed	Nuclear DNA helicase II (RNA helicase A) binds to an F-actin containing shell that surrounds the nucleolus.	NCL UBTF	4.31e-06	4	30	2	14729462
Pubmed	Intracellular redistribution of nuclear and nucleolar proteins during differentiation of 32D murine hemopoietic cells.	NCL UBTF	4.31e-06	4	30	2	12878164
Pubmed	Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.	SMARCC2 CHD4 DNMT1	4.41e-06	37	30	3	24335282
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	SMARCC2 NCL CHD4 GNAS AKAP9 PSIP1 AHNAK	4.51e-06	807	30	7	30575818
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	NCL CHD4 GPBP1L1 PRRC2C AHNAK	5.34e-06	298	30	5	30737378
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	SMARCC2 NCL CHD4 PSIP1 PRRC2C DNMT1 HDGF	6.19e-06	847	30	7	35235311
Pubmed	ABH2 couples regulation of ribosomal DNA transcription with DNA alkylation repair.	NCL UBTF	7.18e-06	5	30	2	23972994
Pubmed	Microspherule protein 1, Mi-2beta, and RET finger protein associate in the nucleolus and up-regulate ribosomal gene transcription.	CHD4 UBTF	7.18e-06	5	30	2	16186106
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	CHD4 BRD8 MIDEAS UBTF	7.50e-06	146	30	4	23892456
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	NR1H2 CHD4 HIVEP2 ZNF688 UBTF DNMT1 HDGF	7.76e-06	877	30	7	20211142
Pubmed	An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.	SMARCC2 CHD4 HDGF	9.76e-06	48	30	3	17620012
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	SMARCC2 CHD4 CBX4 DNMT1	9.99e-06	157	30	4	30186101
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SMARCC2 PPP1R10 ZC3H18 CBX4 MIDEAS	1.03e-05	341	30	5	32971831
Pubmed	Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners.	SMARCC2 CHD4 PSIP1	1.04e-05	49	30	3	19759913
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	SMARCC2 NCL CHD4 PSIP1	1.16e-05	163	30	4	22113938
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	SMARCC2 CHD4 BRD8 MIDEAS	1.27e-05	167	30	4	20362541
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	NCL CHD4 CBX4 GNAS PSIP1 UBTF AHNAK	1.30e-05	949	30	7	36574265
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	SMARCC2 NCL CHD4 GNAS PSIP1 AHNAK	1.72e-05	652	30	6	31180492
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	NCL PDE3A TP53BP2 DNMT1	2.12e-05	190	30	4	15161933
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CHD4 GNAS PSIP1 UBN2 UBTF PRRC2C AHNAK AFG3L2	2.19e-05	1440	30	8	30833792
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	SMARCC2 NCL SLC38A10 CHD4 CBX4 GNAS AKAP9 AHNAK	2.32e-05	1451	30	8	30550785
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PPP1R10 AKAP9 UBTF AHNAK TP53BP2 DNMT1 AFG3L2	2.47e-05	1049	30	7	27880917
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	NCL PRRC2C AHNAK DNMT1	2.69e-05	202	30	4	33005030
Pubmed	CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.	NCL GNAS UBTF PRRC2C AHNAK	2.72e-05	418	30	5	35338135
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SMARCC2 PPP1R10 NCL ZC3H18 CHD4 CBX4 PSIP1	3.01e-05	1082	30	7	38697112
Pubmed	Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.	NCL CHD4 HDGF	3.32e-05	72	30	3	31248990
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	NCL CHD4 PSIP1 UBTF DNMT1	3.52e-05	441	30	5	31239290
Pubmed	N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.	PPP1R10 SLC38A10 ZNF688 AHNAK	3.56e-05	217	30	4	34048709
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	NCL CHD4 BRD8	3.75e-05	75	30	3	25593309
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	NCL CHD4 PSIP1 UBTF PRRC2C DNMT1	4.02e-05	759	30	6	35915203
Pubmed	Dynamic SUMOylation of MORC2 orchestrates chromatin remodelling and DNA repair in response to DNA damage and drives chemoresistance in breast cancer.	CHD4 CBX4	4.72e-05	12	30	2	36793866
Pubmed	The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes.	CHD4 DNMT1	4.72e-05	12	30	2	23708667
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	PPP1R10 NCL ZC3H18 PSIP1 UBTF PRRC2C	5.65e-05	807	30	6	22681889
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	NCL GNAS PRRC2C AHNAK LAD1	5.68e-05	488	30	5	31324722
Pubmed	UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.	NR1H2 CHD4 GNAS PSIP1 UBTF	5.85e-05	491	30	5	36273042
Pubmed	Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.	NCL CHD4 AHNAK DNMT1	7.07e-05	259	30	4	31162944
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SMARCC2 NCL ZC3H18 CHD4 PSIP1 UBTF	7.38e-05	847	30	6	35850772
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	NCL UBTF AHNAK DNMT1	8.19e-05	269	30	4	29511261
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	SMARCC2 NCL CHD4 AHNAK	8.42e-05	271	30	4	32433965
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	CHD4 AKAP9 PRRC2C	9.12e-05	101	30	3	26949739
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	ZC3H18 CHD4 UBTF	9.66e-05	103	30	3	32744500
Pubmed	Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region.	SMARCC2 CHD4	1.09e-04	18	30	2	16217013
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	PSIP1 MIDEAS DNMT1	1.11e-04	108	30	3	19531213
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SMARCC2 CHD4 BRD8 GNAS AHNAK	1.30e-04	582	30	5	20467437
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	NCL ZC3H18 CHD4 GNAS AHNAK DNMT1 HDGF	1.31e-04	1367	30	7	32687490
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	SMARCC2 ZC3H18 CHD4	1.37e-04	116	30	3	21549307
Pubmed	Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.	NCL CBX4 DNMT1	1.37e-04	116	30	3	21282530
Pubmed	Identification of novel ARF binding proteins by two-hybrid screening.	NCL AHNAK	1.50e-04	21	30	2	16582619
Pubmed	The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.	NCL GNAS PSIP1 UBTF AFG3L2	1.55e-04	604	30	5	37616343
Pubmed	Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.	NCL CHD4 DNMT1	1.56e-04	121	30	3	22354994
Interaction	SMC5 interactions	SMARCC2 PPP1R10 NCL ZC3H18 CHD4 BRD8 CBX4 PSIP1 UBN2 MIDEAS UBTF PRRC2C AHNAK DNMT1	3.46e-11	1000	30	14	int:SMC5
Interaction	H3C1 interactions	SMARCC2 CHD4 CBX4 PIEZO2 PSIP1 UBN2 MIDEAS UBTF PRRC2C AHNAK DNMT1 HDGF	2.44e-09	901	30	12	int:H3C1
Interaction	H3-3A interactions	SMARCC2 PPP1R10 NCL CHD4 CBX4 PSIP1 UBN2 MIDEAS UBTF DNMT1 HDGF	4.97e-09	749	30	11	int:H3-3A
Interaction	CDC5L interactions	SMARCC2 NCL ZC3H18 CHD4 BRD8 GNAS AKAP9 UBTF AHNAK TP53BP2 HDGF	1.96e-08	855	30	11	int:CDC5L
Interaction	YAP1 interactions	SMARCC2 PPP1R10 NCL CHD4 BRD8 GNAS UBN2 MIDEAS PRRC2C AHNAK TP53BP2 DNMT1	2.17e-08	1095	30	12	int:YAP1
Interaction	H2BC21 interactions	SMARCC2 PPP1R10 NCL ZC3H18 CHD4 CBX4 PSIP1 MIDEAS AHNAK HDGF	3.64e-08	696	30	10	int:H2BC21
Interaction	H2BC4 interactions	SMARCC2 NCL ZC3H18 PSIP1 TP53BP2 AFG3L2 HDGF	8.45e-08	259	30	7	int:H2BC4
Interaction	H2BC8 interactions	SMARCC2 CHD4 BRD8 CBX4 PSIP1 MIDEAS UBTF DNMT1 HDGF	1.00e-07	576	30	9	int:H2BC8
Interaction	ZNF330 interactions	SMARCC2 NCL ZC3H18 PSIP1 MIDEAS ZNF688 UBTF DNMT1	2.06e-07	446	30	8	int:ZNF330
Interaction	HDAC2 interactions	SMARCC2 NCL ZC3H18 CHD4 GPBP1L1 MIDEAS PRRC2C AHNAK DNMT1 HDGF	2.77e-07	865	30	10	int:HDAC2
Interaction	H3C3 interactions	SMARCC2 ZC3H18 CHD4 CBX4 MIDEAS UBTF DNMT1 HDGF	4.55e-07	495	30	8	int:H3C3
Interaction	CHD4 interactions	SMARCC2 NCL ZC3H18 CHD4 PSIP1 UBTF PRRC2C AHNAK DNMT1 AFG3L2	5.84e-07	938	30	10	int:CHD4
Interaction	NAA40 interactions	PPP1R10 NCL CHD4 PSIP1 UBTF PRRC2C AHNAK TP53BP2 DNMT1 AFG3L2	8.55e-07	978	30	10	int:NAA40
Interaction	CHD3 interactions	SMARCC2 NR1H2 NCL ZC3H18 CHD4 CBX4 PSIP1 UBTF PRRC2C	9.99e-07	757	30	9	int:CHD3
Interaction	POU5F1 interactions	SMARCC2 PPP1R10 NCL CHD4 PSIP1 UBN2 AHNAK HDGF	1.58e-06	584	30	8	int:POU5F1
Interaction	SMARCA5 interactions	SMARCC2 NCL ZC3H18 CHD4 UBTF DNMT1 HDGF	2.02e-06	415	30	7	int:SMARCA5
Interaction	MYCN interactions	SMARCC2 NCL ZC3H18 CHD4 CBX4 PSIP1 MIDEAS UBTF PRRC2C DNMT1 HDGF	2.30e-06	1373	30	11	int:MYCN
Interaction	WWP2 interactions	SMARCC2 PPP1R10 NCL GNAS MIDEAS ZNF688 UBTF PRRC2C TP53BP2	2.36e-06	840	30	9	int:WWP2
Interaction	RNF2 interactions	SMARCC2 NCL CHD4 BRD8 CBX4 AKAP9 UBTF LAD1 AFG3L2	3.03e-06	866	30	9	int:RNF2
Interaction	SUZ12 interactions	SMARCC2 NCL ZC3H18 CHD4 AKAP9 UBTF DNMT1 AFG3L2	3.27e-06	644	30	8	int:SUZ12
Interaction	METAP2 interactions	NCL GPBP1L1 GNAS PSIP1 LAD1 DNMT1	3.67e-06	289	30	6	int:METAP2
Interaction	ACTL6A interactions	SMARCC2 NCL ZC3H18 CHD4 BRD8 HDGF	3.67e-06	289	30	6	int:ACTL6A
Interaction	CEBPB interactions	SMARCC2 NCL CHD4 BRD8 AKAP9 PSIP1 UBTF PRRC2C AHNAK DNMT1 HDGF	3.74e-06	1443	30	11	int:CEBPB
Interaction	EWSR1 interactions	SMARCC2 ZC3H18 CHD4 BRD8 GPBP1L1 PSIP1 UBN2 UBTF HDGF	4.39e-06	906	30	9	int:EWSR1
Interaction	SART1 interactions	SMARCC2 PPP1R10 NCL ZC3H18 CHD4 CBX4	6.24e-06	317	30	6	int:SART1
Interaction	CSNK2A1 interactions	SMARCC2 NCL ZC3H18 CHD4 CBX4 PSIP1 UBTF PRRC2C HDGF	6.80e-06	956	30	9	int:CSNK2A1
Interaction	CEBPA interactions	SMARCC2 CHD4 AKAP9 PSIP1 UBN2 MIDEAS UBTF PRRC2C DNMT1 HDGF	7.51e-06	1245	30	10	int:CEBPA
Interaction	YWHAE interactions	SMARCC2 NCL ZC3H18 CBX4 GPBP1L1 HIVEP2 AKAP9 TP53BP2 DNMT1 HDGF	8.11e-06	1256	30	10	int:YWHAE
Interaction	HDGFL2 interactions	SMARCC2 NCL CHD4 PSIP1 HDGF	9.20e-06	194	30	5	int:HDGFL2
Interaction	SIRT7 interactions	SMARCC2 NCL ZC3H18 CHD4 UBTF PRRC2C AHNAK DNMT1	9.45e-06	744	30	8	int:SIRT7
Interaction	FMR1 interactions	SMARCC2 NCL CHD4 AKAP9 PRRC2C AHNAK DNMT1	1.08e-05	536	30	7	int:FMR1
Interaction	TERF2IP interactions	SMARCC2 PPP1R10 ZC3H18 BRD8 PSIP1 UBTF DNMT1	1.31e-05	552	30	7	int:TERF2IP
Interaction	DEK interactions	SMARCC2 NCL ZC3H18 CHD4 HDGF	1.32e-05	209	30	5	int:DEK
Interaction	TFCP2L1 interactions	SMARCC2 CHD4 BRD8 MIDEAS	1.36e-05	99	30	4	int:TFCP2L1
Interaction	SP1 interactions	SMARCC2 NCL ZC3H18 PSIP1 DNMT1 HDGF	1.39e-05	365	30	6	int:SP1
Interaction	RUVBL1 interactions	SMARCC2 ZC3H18 CHD4 BRD8 GNAS AHNAK HDGF	1.71e-05	575	30	7	int:RUVBL1
Interaction	MEX3A interactions	NCL CHD4 PRRC2C AHNAK TP53BP2 DNMT1	1.86e-05	384	30	6	int:MEX3A
Interaction	HDAC1 interactions	SMARCC2 CHD4 AKAP9 MIDEAS UBTF AHNAK TP53BP2 DNMT1 HDGF	2.22e-05	1108	30	9	int:HDAC1
Interaction	RNF4 interactions	SMARCC2 PPP1R10 NCL CHD4 CBX4 GNAS PSIP1 AHNAK DNMT1 AFG3L2	2.27e-05	1412	30	10	int:RNF4
Interaction	POLDIP3 interactions	NCL ZC3H18 CHD4 PSIP1 HDGF	2.42e-05	237	30	5	int:POLDIP3
Interaction	U2AF1 interactions	NCL ZC3H18 CHD4 PSIP1 HDGF	2.52e-05	239	30	5	int:U2AF1
Interaction	H2BC3 interactions	SMARCC2 ZC3H18 CHD4 CBX4 AHNAK DNMT1	2.54e-05	406	30	6	int:H2BC3
Interaction	HNRNPK interactions	PPP1R10 NCL ZC3H18 CHD4 CBX4 PSIP1 ZNF688 HDGF	2.54e-05	853	30	8	int:HNRNPK
Interaction	EFTUD2 interactions	SMARCC2 NCL ZC3H18 CHD4 PSIP1 PRRC2C AHNAK DNMT1 AFG3L2 HDGF	2.83e-05	1449	30	10	int:EFTUD2
Interaction	NUP43 interactions	ZC3H18 BRD8 PSIP1 UBN2 MIDEAS UBTF PRRC2C	2.92e-05	625	30	7	int:NUP43
Interaction	YTHDC1 interactions	PPP1R10 ZC3H18 SLC38A10 ZNF688 AHNAK AFG3L2	2.95e-05	417	30	6	int:YTHDC1
Interaction	HMGA1 interactions	NCL ZC3H18 CHD4 AKAP9 PSIP1 UBN2	3.03e-05	419	30	6	int:HMGA1
Interaction	FBL interactions	NCL ZC3H18 CHD4 BRD8 UBTF PRRC2C HDGF	3.36e-05	639	30	7	int:FBL
Interaction	BRD2 interactions	SMARCC2 CHD4 CBX4 PSIP1 UBTF DNMT1	3.46e-05	429	30	6	int:BRD2
Interaction	RCL1 interactions	PPP1R10 NCL ZC3H18 HDGF	3.52e-05	126	30	4	int:RCL1
Interaction	OBSL1 interactions	SMARCC2 PPP1R10 NCL CHD4 PSIP1 MIDEAS UBTF AHNAK	3.79e-05	902	30	8	int:OBSL1
Interaction	H2BC9 interactions	SMARCC2 CHD4 PSIP1 AHNAK TP53BP2 DNMT1	4.30e-05	446	30	6	int:H2BC9
Interaction	H3-4 interactions	NCL CHD4 CBX4 PRRC2C AHNAK DNMT1	4.41e-05	448	30	6	int:H3-4
Interaction	MSH6 interactions	SMARCC2 NCL CHD4 DNMT1 HDGF	4.59e-05	271	30	5	int:MSH6
Interaction	AGR2 interactions	SMARCC2 NCL CHD4 GNAS AKAP9 PSIP1 AHNAK HDGF	4.86e-05	934	30	8	int:AGR2
Interaction	RAD18 interactions	PPP1R10 NCL ZC3H18 CHD4 GNAS PRRC2C	4.92e-05	457	30	6	int:RAD18
Interaction	MACROH2A1 interactions	SMARCC2 NCL ZC3H18 CHD4 PSIP1 HDGF	4.98e-05	458	30	6	int:MACROH2A1
Interaction	RNF113A interactions	NCL ZC3H18 CHD4 GNAS MIDEAS UBTF PRRC2C	5.57e-05	692	30	7	int:RNF113A
Interaction	MAB21L2 interactions	CHD4 GNAS UBTF PRRC2C	5.77e-05	143	30	4	int:MAB21L2
Interaction	TOP1 interactions	SMARCC2 PPP1R10 NCL ZC3H18 CHD4 CBX4 HDGF	5.78e-05	696	30	7	int:TOP1
Interaction	BRWD1 interactions	NCL HIVEP2 LAD1	5.91e-05	51	30	3	int:BRWD1
Interaction	RPL10 interactions	NCL ZC3H18 CHD4 PSIP1 UBTF PRRC2C HDGF	6.10e-05	702	30	7	int:RPL10
Interaction	NANOG interactions	CHD4 BRD8 AKAP9 PSIP1 MIDEAS UBTF	6.54e-05	481	30	6	int:NANOG
Interaction	APEX1 interactions	SMARCC2 NCL CHD4 BRD8 PSIP1 UBTF AHNAK DNMT1 HDGF	6.55e-05	1271	30	9	int:APEX1
Interaction	ISG15 interactions	PPP1R10 NCL CBX4 UBTF PRRC2C AHNAK	7.58e-05	494	30	6	int:ISG15
Interaction	BRD3 interactions	SMARCC2 CHD4 CBX4 PSIP1 UBTF DNMT1	7.58e-05	494	30	6	int:BRD3
Interaction	HSPA9 interactions	NCL ZC3H18 CHD4 PRRC2C AHNAK AFG3L2 HDGF	7.61e-05	727	30	7	int:HSPA9
Interaction	FLNB interactions	NCL PRRC2C AHNAK LAD1 HDGF	7.90e-05	304	30	5	int:FLNB
Interaction	ZFP41 interactions	PPP1R10 NCL PRRC2C	8.25e-05	57	30	3	int:ZFP41
Interaction	USP7 interactions	SMARCC2 NR1H2 NCL PDE3A CBX4 PSIP1 UBTF AHNAK DNMT1	8.43e-05	1313	30	9	int:USP7
Interaction	RPS11 interactions	NCL ZC3H18 CHD4 PSIP1 PRRC2C HDGF	8.55e-05	505	30	6	int:RPS11
Interaction	PARP1 interactions	SMARCC2 NCL ZC3H18 CHD4 CBX4 PSIP1 UBTF DNMT1 HDGF	8.58e-05	1316	30	9	int:PARP1
Interaction	RRP1B interactions	PPP1R10 NCL ZC3H18 CHD4 HDGF	9.20e-05	314	30	5	int:RRP1B
Interaction	KMT2A interactions	SMARCC2 NCL CHD4 CBX4 PSIP1	9.20e-05	314	30	5	int:KMT2A
Interaction	RNF180 interactions	CBX4 DNMT1	9.57e-05	10	30	2	int:RNF180
Interaction	MEN1 interactions	SMARCC2 PPP1R10 ZC3H18 CHD4 CBX4 PSIP1 MIDEAS UBTF	9.62e-05	1029	30	8	int:MEN1
Interaction	ATXN1 interactions	SMARCC2 PPP1R10 NCL ZC3H18 CHD4 GNAS PRRC2C DNMT1	1.03e-04	1039	30	8	int:ATXN1
Interaction	RBM25 interactions	SMARCC2 PPP1R10 ZC3H18 CHD4 CBX4	1.05e-04	323	30	5	int:RBM25
Interaction	FOXA1 interactions	SMARCC2 CHD4 PSIP1 UBTF DNMT1 HDGF	1.06e-04	525	30	6	int:FOXA1
Interaction	H2BC6 interactions	BRD8 UBTF HDGF	1.06e-04	62	30	3	int:H2BC6
Interaction	KIF20A interactions	SMARCC2 NCL ZC3H18 CHD4 PIEZO2 GNAS PSIP1 AHNAK	1.12e-04	1052	30	8	int:KIF20A
Interaction	PRP4K interactions	SMARCC2 PPP1R10 ZC3H18 CHD4 CBX4	1.15e-04	329	30	5	int:PRP4K
Interaction	H2BC5 interactions	NCL ZC3H18 CHD4 AFG3L2 HDGF	1.18e-04	331	30	5	int:H2BC5
Interaction	B3GNT2 interactions	NCL PDE3A GNAS UBTF PRRC2C AHNAK	1.26e-04	542	30	6	int:B3GNT2
Interaction	NONO interactions	PPP1R10 NCL ZC3H18 CHD4 CBX4 AKAP9	1.35e-04	549	30	6	int:NONO
Interaction	H4C6 interactions	CHD4 GNAS HDGF	1.46e-04	69	30	3	int:H4C6
Interaction	METTL14 interactions	NCL SLC38A10 GNAS PSIP1 UBTF AHNAK	1.48e-04	558	30	6	int:METTL14
Interaction	WDR5 interactions	SMARCC2 NCL ZC3H18 CHD4 PSIP1 PRRC2C DNMT1 HDGF	1.54e-04	1101	30	8	int:WDR5
Interaction	YWHAH interactions	CBX4 GPBP1L1 HIVEP2 AKAP9 PRRC2C AHNAK TP53BP2 DNMT1	1.55e-04	1102	30	8	int:YWHAH
Interaction	SOX2 interactions	SMARCC2 NCL CHD4 BRD8 CBX4 PSIP1 UBN2 MIDEAS UBTF	1.56e-04	1422	30	9	int:SOX2
Interaction	DAXX interactions	NCL ZC3H18 CHD4 UBTF DNMT1	1.59e-04	353	30	5	int:DAXX
Interaction	DDX47 interactions	NCL ZC3H18 CHD4 HDGF	1.60e-04	186	30	4	int:DDX47
Interaction	EIF3A interactions	NCL ZC3H18 CHD4 GPBP1L1 PRRC2C	1.64e-04	355	30	5	int:EIF3A
Interaction	SRSF1 interactions	NCL ZC3H18 CHD4 PSIP1 PRRC2C HDGF	1.66e-04	570	30	6	int:SRSF1
Interaction	PYHIN1 interactions	ZC3H18 CHD4 UBN2 UBTF DNMT1	1.70e-04	358	30	5	int:PYHIN1
Interaction	KAT5 interactions	BRD8 PSIP1 UBTF DNMT1 HDGF	1.70e-04	358	30	5	int:KAT5
Interaction	RBBP4 interactions	SMARCC2 ZC3H18 CHD4 UBN2 DNMT1 HDGF	1.71e-04	573	30	6	int:RBBP4
Interaction	CIT interactions	SMARCC2 NCL CHD4 GNAS AKAP9 PSIP1 UBTF PRRC2C AHNAK	1.80e-04	1450	30	9	int:CIT
Interaction	ZBTB7B interactions	NCL CHD4 GNAS AKAP9 UBTF	1.88e-04	366	30	5	int:ZBTB7B
Interaction	GNL3 interactions	NCL ZC3H18 CHD4 BRD8 HDGF	1.93e-04	368	30	5	int:GNL3
Cytoband	17q25.3	SLC38A10 CBX4	2.00e-03	101	30	2	17q25.3
Cytoband	Ensembl 112 genes in cytogenetic band chr18p11	PIEZO2 AFG3L2	8.33e-03	210	30	2	chr18p11
GeneFamily	PWWP domain containing	PSIP1 HDGF	2.93e-04	22	21	2	1147
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R10 AKAP9 TP53BP2	1.15e-03	181	21	3	694
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	SMARCC2 MIDEAS	1.71e-03	53	21	2	532
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	PDE3A SLC38A10 CHD4 CBX4 PRRC2C AHNAK DNMT1	7.78e-07	467	30	7	M1347
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	PDE3A SLC38A10 CHD4 CBX4 PRRC2C AHNAK DNMT1	9.88e-07	484	30	7	MM999
Coexpression	MCBRYAN_PUBERTAL_BREAST_6_7WK_UP	SLC38A10 CHD4 BRD8 AKAP9 UBTF	2.93e-06	199	30	5	M2155
Coexpression	MCBRYAN_PUBERTAL_BREAST_6_7WK_UP	SLC38A10 CHD4 BRD8 AKAP9 UBTF	2.93e-06	199	30	5	MM991
Coexpression	GSE24814_STAT5_KO_VS_WT_PRE_BCELL_DN	SLC38A10 CHD4 AKAP9 PRRC2C TP53BP2	3.00e-06	200	30	5	M8427
Coexpression	MENON_FETAL_KIDNEY_0_CAP_MESENCHYME_CELLS	NCL CHD4 PSIP1 DNMT1	3.33e-06	90	30	4	M39250
Coexpression	RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN	SLC38A10 GPBP1L1 HIVEP2 GNAS AKAP9 UBN2 UBTF	2.80e-05	807	30	7	M16651
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	PDE3A PIEZO2 AKAP9 AHNAK	4.80e-05	177	30	4	M39245
Coexpression	AIZARANI_LIVER_C39_EPCAM_POS_BILE_DUCT_CELLS_4	AHNAK TP53BP2 LAD1 HDGF	5.58e-05	184	30	4	M39135
Coexpression	GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN	ZC3H18 UBTF PRRC2C AHNAK	7.57e-05	199	30	4	M9443
Coexpression	GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_DN	PPP1R10 CBX4 DNMT1 PNPO	7.57e-05	199	30	4	M3912
Coexpression	GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP	NCL UBTF TP53BP2 AFG3L2	7.57e-05	199	30	4	M5258
Coexpression	GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_UP	PPP1R10 AHNAK LAD1 DNMT1	7.72e-05	200	30	4	M5973
Coexpression	TABULA_MURIS_SENIS_KIDNEY_KIDNEY_COLLECTING_DUCT_PRINCIPAL_CELL_AGEING	AKAP9 UBN2 PRRC2C AHNAK HDGF	7.82e-05	394	30	5	MM3724
Coexpression	LOPEZ_MBD_TARGETS	SMARCC2 PPP1R10 AKAP9 MIDEAS TP53BP2 PNPO HDGF	8.03e-05	953	30	7	M4120
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	NCL AKAP9 PSIP1 PRRC2C AHNAK DNMT1	3.55e-09	197	30	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 NCL CHD4 AKAP9 PRRC2C	1.54e-07	187	30	5	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	NCL CHD4 GNAS PRRC2C AHNAK	2.15e-07	200	30	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCL CHD4 HIVEP2 DNMT1	5.35e-06	173	30	4	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCL CHD4 HIVEP2 DNMT1	5.35e-06	173	30	4	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 PDE3A PRRC2C AHNAK	5.73e-06	176	30	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 CHD4 PRRC2C AHNAK	6.83e-06	184	30	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	ILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPP1R10 GNAS AKAP9 AHNAK	7.59e-06	189	30	4	a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCL CHD4 AKAP9 AHNAK	7.75e-06	190	30	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	BRD8 AKAP9 PRRC2C HDGF	8.08e-06	192	30	4	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A10 CHD4 AKAP9 PRRC2C	8.58e-06	195	30	4	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A10 CHD4 AKAP9 PRRC2C	8.58e-06	195	30	4	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	moderate-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PPP1R10 AKAP9 PRRC2C AHNAK	9.12e-06	198	30	4	0a868098b1ee4b28b2149ed766acb09e9c0ce14c
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PPP1R10 SLC38A10 AKAP9 HECTD2	9.49e-06	200	30	4	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	severe-CD8+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCL GNAS PSIP1 PRRC2C	9.49e-06	200	30	4	61c7c08460856c188e62edf1fa62855578146fc8
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCL AKAP9 PRRC2C AHNAK	9.49e-06	200	30	4	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	NCL GNAS PSIP1 PRRC2C	9.49e-06	200	30	4	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate\|6m / Sample Type, Dataset, Time_group, and Cell type.	NCL CHD4 AKAP9 PRRC2C	9.49e-06	200	30	4	7c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	GNAS AKAP9 PRRC2C	1.08e-04	138	30	3	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A PIEZO2 GNAS	1.49e-04	154	30	3	3211f003f4d1735c7cab9b6cc68af3e0bbfba35e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A PIEZO2 GNAS	1.49e-04	154	30	3	c0fe767fc9ab45b2dfa71171f2a673a4a8decbaf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A PIEZO2 GNAS	1.49e-04	154	30	3	4c2a7590791c2255b15dab82c3622f71f9ffd949
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A PIEZO2 GNAS	1.80e-04	164	30	3	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3A PIEZO2 HECTD2	1.96e-04	169	30	3	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A PIEZO2 GNAS	2.00e-04	170	30	3	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A PIEZO2 GNAS	2.00e-04	170	30	3	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A PIEZO2 GNAS	2.00e-04	170	30	3	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	NCL PRRC2C AHNAK	2.03e-04	171	30	3	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE3A PIEZO2 DNMT1	2.25e-04	177	30	3	0e74980a7686c31fcf1476b8f19a3392541df240
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 AKAP9 PRRC2C	2.29e-04	178	30	3	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	normal-na-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	NCL PSIP1 PRRC2C	2.29e-04	178	30	3	fa3585383a1e7da460c88a802aaa81246d681b6b
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	NCL PIEZO2 HIVEP2	2.29e-04	178	30	3	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C AHNAK PNPO	2.29e-04	178	30	3	1a578d16008a450c42e73a996247ffecdc2c43f0
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 NCL PRRC2C	2.44e-04	182	30	3	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 CHD4 PRRC2C	2.44e-04	182	30	3	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	droplet-Marrow-nan-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C AHNAK DNMT1	2.44e-04	182	30	3	bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 CHD4 PRRC2C	2.44e-04	182	30	3	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 NCL PRRC2C	2.48e-04	183	30	3	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 NCL PRRC2C	2.48e-04	183	30	3	3fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HIVEP2 PSIP1 PRRC2C	2.52e-04	184	30	3	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD4 PRRC2C AHNAK	2.56e-04	185	30	3	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPP1R10 GNAS AKAP9	2.64e-04	187	30	3	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD4 AKAP9 PRRC2C	2.68e-04	188	30	3	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PDE3A PIEZO2 AHNAK	2.81e-04	191	30	3	fa380a8752de158974b2ae5e741573439719cc0d
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 HIVEP2 AHNAK	2.85e-04	192	30	3	b016e229300c183e14c0e2bba494bf49c7899112
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 HIVEP2 AHNAK	2.85e-04	192	30	3	ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A10 GNAS UBN2	2.85e-04	192	30	3	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Severe / Disease group, lineage and cell class	NCL HIVEP2 PSIP1	2.90e-04	193	30	3	beb862d38b88572836b0a797c8efef7a2492e0b9
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCL HIVEP2 PSIP1	2.90e-04	193	30	3	f4310faa13fc8ce99a217e2d1c9cc733683797a1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NCL HIVEP2 PSIP1	2.90e-04	193	30	3	f8af695457d2a0a911a5ac491742465864ebda37
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCL HIVEP2 PSIP1	2.90e-04	193	30	3	2901d7a9672a8cf70c9f1c752685b45e4d79ac70
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	NCL HIVEP2 PSIP1	2.90e-04	193	30	3	089aece40130034a89a5213be778f10b0787eeba
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HIVEP2 PSIP1 AHNAK	2.90e-04	193	30	3	194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCell	droplet-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 GNAS MIDEAS	2.90e-04	193	30	3	e55f79bad6888b84b0ad5fccded498b170e3c6dc
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCL GNAS PRRC2C	2.90e-04	193	30	3	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCL AKAP9 PRRC2C	2.94e-04	194	30	3	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GNAS PRRC2C AHNAK	2.99e-04	195	30	3	4d63e0dca30ae57960459d2fbcba09122273e37b
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GNAS PRRC2C AHNAK	2.99e-04	195	30	3	661af601a3561fe3aacf2444ad7b8927fa88b48a
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPBP1L1 PRRC2C AHNAK	2.99e-04	195	30	3	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	normal-na-Lymphocytic_T-T4_naive-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	NCL PSIP1 PRRC2C	3.03e-04	196	30	3	feb1c768cf66c64b6c892905d2d865946e70812f
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 SLC38A10 AHNAK	3.03e-04	196	30	3	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R10 SLC38A10 AHNAK	3.03e-04	196	30	3	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	Control-Classical_Monocyte-cMono_2\|Classical_Monocyte / Disease condition and Cell class	GNAS PRRC2C AHNAK	3.08e-04	197	30	3	eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCell	facs-Heart-RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3A PIEZO2 PRRC2C	3.08e-04	197	30	3	940cf1e54d7c820e04946258a8b784f35c6a144c
ToppCell	(2)_Fibroblasts-(24)_Fibro-5\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	PIEZO2 HIVEP2 AHNAK	3.08e-04	197	30	3	83a4b79fbfa1cf63441dee4424c3b87c988287bf
ToppCell	10x3'2.3-week_17-19\|World / cell types per 3 fetal stages;per 3',per 5'	PPP1R10 CBX4 GNAS	3.08e-04	197	30	3	f5cfad0b42d0f817e22cc78b9bfb2b4b7e4330ed
ToppCell	Mild\|World / Condition, Lineage, Cell class and cell subclass	SMARCC2 NR1H2 AKAP9	3.08e-04	197	30	3	476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC38A10 AKAP9 TP53BP2	3.08e-04	197	30	3	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	myeloid-CD34+_Monoblast\|myeloid / Lineage and Cell class	NCL DNMT1 HDGF	3.12e-04	198	30	3	e26b98a8380e693110a97d8e5a353998f8d67c6d
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLC38A10 AKAP9 TP53BP2	3.12e-04	198	30	3	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	PBMC_fresh-frozen\|World / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCL PRRC2C AHNAK	3.12e-04	198	30	3	dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	GNAS AKAP9 PRRC2C	3.17e-04	199	30	3	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	metastatic_Brain-Epithelial_cells\|metastatic_Brain / Location, Cell class and cell subclass	GNAS AKAP9 LAD1	3.17e-04	199	30	3	5c0cd611dbf2014e0ae6ce9fe8b619ceb4006e43
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AKAP9 PRRC2C AHNAK	3.17e-04	199	30	3	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	GNAS AKAP9 PRRC2C	3.17e-04	199	30	3	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NCL PSIP1 DNMT1	3.17e-04	199	30	3	8b7f84a1e385c6a9bd45a5d41f75e30819dbe32d
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	BRD8 AKAP9 PRRC2C	3.17e-04	199	30	3	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HIVEP2 PSIP1 PRRC2C	3.17e-04	199	30	3	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	metastatic_Brain-Epithelial_cells-Malignant_cells\|metastatic_Brain / Location, Cell class and cell subclass	GNAS AKAP9 LAD1	3.17e-04	199	30	3	56df2b342c77b33299cfb407e1e05f42940f2946
ToppCell	HSPCs\|World / Lineage and Cell class	NCL DNMT1 HDGF	3.17e-04	199	30	3	df1ffc416c6946f1ba182f242a50ee41a571d565
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	AKAP9 PRRC2C AHNAK	3.22e-04	200	30	3	e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell	Brain_organoid-organoid_Tanaka_cellReport\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	NCL CHD4 AHNAK	3.22e-04	200	30	3	b0ba486b55be18a4236bd2644f02352651f4b1fe
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCL PRRC2C AHNAK	3.22e-04	200	30	3	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GNAS PSIP1 AHNAK	3.22e-04	200	30	3	b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Severe / Disease, condition lineage and cell class	NCL HIVEP2 PSIP1	3.22e-04	200	30	3	deeed668b129e66156b5f6abe1a07a9bf842a14d
ToppCell	severe\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCL GNAS PRRC2C	3.22e-04	200	30	3	accc618d6b960bff30cb531c1226295bfc8650f6
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	PSIP1 DNMT1 HDGF	3.22e-04	200	30	3	5f2fbd789cc16af411a01c3199583888b260ae91
ToppCell	severe-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GNAS PSIP1 PRRC2C	3.22e-04	200	30	3	e83558090a079dd9e40e0d3b5d9917fbd2695ec4
ToppCell	severe-CD4+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GNAS PSIP1 PRRC2C	3.22e-04	200	30	3	f74bdabadca8ad6dae1b6e6812c66325aac50db0
ToppCell	LPS_IL1RA\|World / Treatment groups by lineage, cell group, cell type	HIVEP2 PRRC2C TP53BP2	3.22e-04	200	30	3	a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCL AKAP9 PRRC2C	3.22e-04	200	30	3	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	severe-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCL GNAS AHNAK	3.22e-04	200	30	3	6aa77955017d073a96324e4db6b9950a2ec46cf8
ToppCell	control-gd_T\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PPP1R10 CBX4 GNAS	3.22e-04	200	30	3	b188f2acb9bd4f5f1ad4c3d3ddb9a55854a8b74b
Computational	Neighborhood of GNB1	SMARCC2 NCL CHD4 BRD8 PRRC2C DNMT1 AFG3L2	3.36e-07	305	18	7	MORF_GNB1
Computational	Neighborhood of ACP1	NCL CHD4 BRD8 GNAS PRRC2C HDGF	8.12e-07	211	18	6	MORF_ACP1
Computational	Neighborhood of RAD23A	NCL CHD4 PRRC2C DNMT1 AFG3L2 HDGF	1.47e-05	348	18	6	MORF_RAD23A
Computational	Neighborhood of XRCC5	SMARCC2 NCL BRD8 DNMT1 AFG3L2	3.25e-05	235	18	5	MORF_XRCC5
Computational	Neighborhood of UBE2I	NCL CHD4 BRD8 GNAS HDGF	3.45e-05	238	18	5	MORF_UBE2I
Computational	Neighborhood of HDAC1	NCL CHD4 PRRC2C AFG3L2 HDGF	4.72e-05	254	18	5	MORF_HDAC1
Computational	Genes upregulated in subsets of cells of a given type within various tumors	NCL AKAP9 PRRC2C	6.92e-05	49	18	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
Computational	Neighborhood of RPA2	SMARCC2 PPP1R10 BRD8 AFG3L2	2.53e-04	193	18	4	MORF_RPA2
Computational	Neighborhood of DAP3	SMARCC2 NCL BRD8 AFG3L2	2.63e-04	195	18	4	MORF_DAP3
Computational	Neighborhood of ANP32B	NCL CHD4 GNAS HDGF	2.79e-04	198	18	4	MORF_ANP32B
Computational	Neighborhood of AATF	SMARCC2 NCL BRD8 AFG3L2	3.43e-04	209	18	4	MORF_AATF
Computational	Neighborhood of CCNI	CHD4 GNAS HDGF	3.96e-04	88	18	3	MORF_CCNI
Computational	Genes in the cancer module 32.	NCL CHD4 CBX4 GNAS	5.89e-04	241	18	4	MODULE_32
Computational	Neighborhood of PAPSS1	SMARCC2 BRD8 AFG3L2	6.28e-04	103	18	3	MORF_PAPSS1
Computational	Neighborhood of EIF3S2	NCL BRD8 DNMT1 AFG3L2	6.36e-04	246	18	4	MORF_EIF3S2
Computational	Neighborhood of DEK	NCL BRD8 PRRC2C AFG3L2	8.29e-04	264	18	4	MORF_DEK
Computational	Neighborhood of BUB3	NCL BRD8 DNMT1 AFG3L2	9.93e-04	277	18	4	MORF_BUB3
Computational	Neighborhood of CSNK2B	CHD4 PRRC2C AFG3L2 HDGF	1.13e-03	287	18	4	MORF_CSNK2B
Computational	Neighborhood of PPP2CA	NCL BRD8 AFG3L2	1.21e-03	129	18	3	MORF_PPP2CA
Computational	Neighborhood of EIF4A2	SMARCC2 NCL BRD8	1.47e-03	138	18	3	MORF_EIF4A2
Computational	Neighborhood of ACTG1	NCL GNAS HDGF	1.47e-03	138	18	3	MORF_ACTG1
Computational	Neighborhood of NPM1	NCL GNAS HDGF	2.32e-03	162	18	3	MORF_NPM1
Computational	Neighborhood of CTBP1	NCL CHD4 HDGF	2.57e-03	168	18	3	MORF_CTBP1
Computational	Neighborhood of G22P1	NCL CHD4 HDGF	2.75e-03	172	18	3	MORF_G22P1
Computational	Genes upregulated in subsets of cells of a given type within various tumors	AKAP9 AHNAK	2.97e-03	49	18	2	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Computational	Neighborhood of PRKDC	BRD8 DNMT1 AFG3L2	3.70e-03	191	18	3	MORF_PRKDC
Computational	Neighborhood of PPP1CC	NCL BRD8	3.87e-03	56	18	2	GCM_PPP1CC
Computational	Neighborhood of ESPL1	DNMT1 AFG3L2	4.57e-03	61	18	2	MORF_ESPL1
Computational	Neighborhood of SMC1L1	NCL PRRC2C	4.72e-03	62	18	2	MORF_SMC1L1
Computational	Neighborhood of SNRP70	NCL BRD8	4.72e-03	62	18	2	MORF_SNRP70
Computational	Neighborhood of SART1	NCL HDGF	4.87e-03	63	18	2	MORF_SART1
Computational	Neighborhood of TERF1	SMARCC2 BRD8	5.49e-03	67	18	2	MORF_TERF1
Computational	Neighborhood of CBFB	NCL BRD8	5.98e-03	70	18	2	GCM_CBFB
Computational	Neighborhood of CUL1	BRD8 AFG3L2	6.32e-03	72	18	2	MORF_CUL1
Computational	Neighborhood of KPNB1	NCL PSIP1	6.49e-03	73	18	2	GNF2_KPNB1
Computational	Neighborhood of DDB1	SMARCC2 BRD8 AFG3L2	7.49e-03	246	18	3	MORF_DDB1
Computational	Genes in the cancer module 123.	CHD4 CBX4 DNMT1	7.58e-03	247	18	3	MODULE_123
Computational	Neighborhood of PSME1	NCL BRD8	8.71e-03	85	18	2	GCM_PSME1
Computational	Neighborhood of RAN	NCL GNAS HDGF	9.48e-03	268	18	3	MORF_RAN
Computational	Neighborhood of UBE2N	CHD4 PRRC2C	1.08e-02	95	18	2	MORF_UBE2N
Disease	Global developmental delay	SMARCC2 UBTF PNPO	3.00e-04	133	29	3	C0557874
Disease	Neoplasm Invasiveness	AHNAK TP53BP2 DNMT1	7.74e-04	184	29	3	C0027626
Disease	response to hydrochlorothiazide, triglyceride measurement	PIEZO2 DNMT1	9.81e-04	47	29	2	EFO_0004530, EFO_0005202

Protein segments in the cluster

Peptide	Gene	Start	Entry
KEKELDRKPEDVPPE	AKAP9	1701	Q99996
KDLAAKRRPEEKEPE	DNMT1	291	P26358
ETPKRKRGEKGEVVE	BRD8	76	Q9H0E9
KEREKEKEEPPGEKV	AFG3L2	781	Q9Y4W6
DLKGPEVDIRDPKVD	AHNAK	4621	Q09666
DDGEVPLREKEKKVR	TP53BP2	441	Q13625
LVGREPEERKKGVPE	LAD1	161	O00515
PPMEIREEKKEDKVE	GPBP1L1	136	Q9HC44
PEERKGKESEREKLP	HECTD2	21	Q5U5R9
EEEEEKGKPRGEEIP	PDE3A	1121	Q14432
PKRPKEAENPEGEEK	HDGF	166	P51858
RVEGPVKKLPEEEAE	PNPO	141	Q9NVS9
EEEEEEPVKEAPGKR	NCL	266	P19338
PRDPEESKEPKEEKQ	GNAS	201	O95467
AEEKKVEAPPKRREE	CBX4	316	O00257
PKREVKEPRKEGEEE	MIDEAS	931	Q6PJG2
KEPRKEGEEEVPEIQ	MIDEAS	936	Q6PJG2
KVVVEPPEGEEKVEK	CHD4	1606	Q14839
PPEGEEKVEKAEVKE	CHD4	1611	Q14839
GREKPKLPKEREELE	SLC38A10	441	Q9HBR0
VIPDPEEEPERKRKK	NR1H2	61	P55055
KEREKLEEKIEPREP	PRRC2C	591	Q9Y520
PEKEKEPKEGQEEVL	SMARCC2	821	Q8TAQ2
DKGREPEEKPLDRPE	CNGB3	741	Q9NQW8
PKKDEEGQKEEDKPR	PSIP1	231	O75475
EGQKEEDKPRKEPDK	PSIP1	236	O75475
EDDDEKPGKRVIGPR	UBN2	586	Q6ZU65
LEKPEVRKLAEPGEE	PIEZO2	851	Q9H5I5
EEEPEEVPRAKGPRK	ZNF688	111	P0C7X2
EERGKLPESPKRAEE	UBTF	476	P17480
IRVTEEPDKPEKEKE	HIVEP2	891	P31629
ETRAEEAPEKKREKP	PPP1R10	181	Q96QC0
EEGEVKDPSDRKVRP	ZC3H18	206	Q86VM9