Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.28e-0651023GO:0052871
GeneOntologyMolecularFunctionfibroblast growth factor receptor activity

FGFR1 FGFR3 FGFR4

1.28e-0651023GO:0005007
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F3 CYP4F11

4.46e-0671023GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F3 CYP4F11

4.46e-0671023GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.51e-05101023GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.51e-05101023GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.51e-05101023GO:0102033
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

2.58e-0521022GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

2.58e-0521022GO:0097259
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F11

3.57e-05131023GO:0016713
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

FMO4 CYP4F2 CYP4F3 CYP4F11

5.09e-05401024GO:0016709
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

AMHR2 TIE1 FGFR1 FGFR3 FGFR4

7.48e-05851025GO:0019199
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F2 CYP4F3 CYP4F11

2.42e-04241023GO:0008392
GeneOntologyMolecularFunctioncell-cell adhesion mediator activity

DSCAML1 IGSF9 ROBO3 CNTN1

2.68e-04611024GO:0098632
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

TIE1 FGFR1 FGFR3 FGFR4

3.42e-04651024GO:0004714
GeneOntologyMolecularFunctionfibroblast growth factor binding

FGFR1 FGFR3 FGFR4

3.46e-04271023GO:0017134
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F2 CYP4F3 CYP4F11

3.46e-04271023GO:0008391
GeneOntologyMolecularFunctioncell adhesion mediator activity

DSCAML1 IGSF9 ROBO3 CNTN1

6.21e-04761024GO:0098631
GeneOntologyMolecularFunctionaromatase activity

CYP4F2 CYP4F3 CYP4F11

7.52e-04351023GO:0070330
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

TIE1 DSTYK FGFR1 FGFR3 FGFR4

8.92e-041451025GO:0004713
GeneOntologyMolecularFunctionNADH dehydrogenase (ubiquinone) activity

NDUFA8 NDUFB6 NDUFS1

1.20e-03411023GO:0008137
GeneOntologyMolecularFunctionoxidoreductase activity

FMO4 CYP4F2 NDUFA8 NXN NDUFB6 NDUFS1 PEDS1 CYP4F3 CYP4F11 ALDH7A1 ALOX15B

1.84e-0376610211GO:0016491
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F11

2.01e-03491023GO:0016712
GeneOntologyMolecularFunctionarachidonate binding

CYP4F2 CYP4F11

2.60e-03151022GO:0050544
GeneOntologyMolecularFunctionmonooxygenase activity

FMO4 CYP4F2 CYP4F3 CYP4F11

2.88e-031151024GO:0004497
GeneOntologyMolecularFunctionicosanoid binding

CYP4F2 CYP4F11

2.96e-03161022GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F2 CYP4F11

2.96e-03161022GO:0050543
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

FMO4 CYP4F2 PEDS1 CYP4F3 CYP4F11

3.20e-031941025GO:0016705
GeneOntologyMolecularFunctionhistone H4 methyltransferase activity

PRMT1 PRDM6

3.34e-03171022GO:0140939
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

NDUFA8 NDUFB6 NDUFS1

3.59e-03601023GO:0016655
GeneOntologyMolecularFunctionoxidoreduction-driven active transmembrane transporter activity

NDUFA8 NDUFB6 NDUFS1

5.31e-03691023GO:0015453
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F2 CYP4F3 CYP4F11

2.46e-0661043GO:0036101
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F2 CYP4F3 ACOT2 CYP4F11

4.16e-06221044GO:1901569
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F2 CYP4F3 CYP4F11

4.30e-0671043GO:0036102
GeneOntologyBiologicalProcesstissue morphogenesis

CPLANE2 LIAS CECR2 FIGNL2 RIPK4 ADAMTS5 SIX4 SIRT6 CITED2 CCM2 TIE1 MACF1 FGFR1 FGFR3 SIX2

5.26e-0675010415GO:0048729
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F2 CYP4F3 CYP4F11

6.85e-0681043GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F2 CYP4F3 CYP4F11

2.00e-05111043GO:1901523
GeneOntologyBiologicalProcessaxon development

RELN SZT2 FIGNL2 DCC DSCAML1 SCARF1 DST HMCN2 MACF1 IGSF9 FGFR3 ROBO3 CNTN1

2.07e-0564210413GO:0061564
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F2 CYP4F3 CYP4F11

2.65e-05121043GO:0042758
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

CYP4F2 CYP4F3 ACOT2 CYP4F11 ALOX15B

5.93e-05821045GO:1901568
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

LIAS CECR2 FIGNL2 RIPK4 SIX4 SIRT6 CITED2 CCM2 TIE1 FGFR1 FGFR3 SIX2

6.70e-0561910412GO:0002009
GeneOntologyBiologicalProcessneuron projection development

RELN SZT2 CECR2 FIGNL2 TRIOBP DCC DSCAML1 NCDN SCARF1 DST HMCN2 MACF1 PRMT1 IGSF9 FGFR1 FGFR3 ROBO3 CNTN1

7.05e-05128510418GO:0031175
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F11

7.53e-0531042GO:0042361
GeneOntologyBiologicalProcessdendrite self-avoidance

DSCAML1 IGSF9 ROBO3

9.62e-05181043GO:0070593
GeneOntologyBiologicalProcessear development

CEBPD CECR2 TRIOBP SIX4 CCM2 FGFR1 FGFR3 SIX2

9.86e-052851048GO:0043583
GeneOntologyBiologicalProcessepithelium development

LIAS CECR2 SIPA1L3 FIGNL2 TRIOBP IRF6 RIPK4 SIX4 SIRT6 KLF2 CITED2 CCM2 TIE1 FGFR1 FGFR3 PRKDC FGFR4 SIX2 ALOX15B

1.25e-04146910419GO:0060429
GeneOntologyBiologicalProcessfat-soluble vitamin metabolic process

CYP4F2 FGFR1 FGFR4 CYP4F11

1.27e-04511044GO:0006775
GeneOntologyBiologicalProcessaxonogenesis

RELN SZT2 DCC DSCAML1 DST HMCN2 MACF1 IGSF9 FGFR3 ROBO3 CNTN1

1.34e-0456610411GO:0007409
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F11

1.50e-0441042GO:0009233
GeneOntologyBiologicalProcessalveolar secondary septum development

FGFR3 FGFR4

1.50e-0441042GO:0061144
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F11

1.50e-0441042GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F11

1.50e-0441042GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F11

1.50e-0441042GO:0042377
GeneOntologyBiologicalProcesspositive regulation of parathyroid hormone secretion

FGFR1 FGFR4

1.50e-0441042GO:2000830
GeneOntologyBiologicalProcessregulation of animal organ morphogenesis

SIX4 CITED2 FGFR1 FGFR4 SIX2

2.38e-041101045GO:2000027
GeneOntologyBiologicalProcessregulation of parathyroid hormone secretion

FGFR1 FGFR4

2.49e-0451042GO:2000828
GeneOntologyBiologicalProcessinner ear development

CEBPD CECR2 TRIOBP SIX4 CCM2 FGFR1 FGFR3

2.97e-042531047GO:0048839
GeneOntologyBiologicalProcessregulation of morphogenesis of a branching structure

SIX4 SIRT6 FGFR1 SIX2

3.26e-04651044GO:0060688
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

FIGNL2 SIX4 SIRT6 CITED2 TIE1 FGFR1 SIX2

3.34e-042581047GO:0001763
GeneOntologyBiologicalProcessneuron development

RELN SZT2 CECR2 FIGNL2 TRIOBP DCC DSCAML1 NCDN SCARF1 DST HMCN2 MACF1 PRMT1 IGSF9 FGFR1 FGFR3 ROBO3 CNTN1

3.54e-04146310418GO:0048666
GeneOntologyBiologicalProcesspositive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

FGFR1 FGFR3

3.73e-0461042GO:0090080
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F11

3.73e-0461042GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F11

3.73e-0461042GO:0062232
GeneOntologyBiologicalProcesspositive regulation of hemoglobin biosynthetic process

ABCB10 PRMT1

3.73e-0461042GO:0046985
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

RELN SZT2 TRIOBP DCC DSCAML1 DST HMCN2 MACF1 IGSF9 FGFR3 ROBO3 CNTN1

3.86e-0474810412GO:0048667
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4F2 CYP4F3 CYP4F11 ALOX15B

3.88e-04681044GO:0019369
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

CYP4F2 CYP4F3 ACOT2 CYP4F11 ALOX15B

4.14e-041241045GO:0001676
GeneOntologyBiologicalProcesschondrocyte proliferation

SIRT6 FGFR3 SIX2

5.05e-04311043GO:0035988
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

CYP4F2 SCARF1 CYP4F3 CYP4F11

5.08e-04731044GO:1901616
GeneOntologyBiologicalProcesscerebral cortex tangential migration

RELN FGFR1

5.20e-0471042GO:0021800
GeneOntologyBiologicalProcesssensory perception of umami taste

CALHM1 GNAT3

5.20e-0471042GO:0050917
GeneOntologyBiologicalProcesssensory perception of sweet taste

CALHM1 GNAT3

5.20e-0471042GO:0050916
GeneOntologyBiologicalProcessparathyroid hormone secretion

FGFR1 FGFR4

5.20e-0471042GO:0035898
GeneOntologyBiologicalProcessregulation of animal organ formation

CITED2 FGFR1 FGFR4

5.55e-04321043GO:0003156
GeneOntologyBiologicalProcessregulation of morphogenesis of an epithelium

SIX4 SIRT6 FGFR1 SIX2

5.92e-04761044GO:1905330
GeneOntologyBiologicalProcessaxon guidance

RELN DCC DSCAML1 HMCN2 IGSF9 ROBO3 CNTN1

6.06e-042851047GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

RELN DCC DSCAML1 HMCN2 IGSF9 ROBO3 CNTN1

6.19e-042861047GO:0097485
GeneOntologyBiologicalProcesschordate embryonic development

LIAS CECR2 SIX4 NXN DSCAML1 KLF2 CITED2 CCM2 TIE1 PRMT1 FGFR1 PRKDC SIX2

6.30e-0490610413GO:0043009
GeneOntologyBiologicalProcessregulation of hemoglobin biosynthetic process

ABCB10 PRMT1

6.91e-0481042GO:0046984
GeneOntologyBiologicalProcessnegative regulation of fibroblast growth factor production

FGFR1 FGFR4

6.91e-0481042GO:0090272
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

LIAS CECR2 SIX4 NXN DSCAML1 KLF2 CITED2 CCM2 TIE1 PRMT1 FGFR1 PRKDC SIX2

7.95e-0492910413GO:0009792
GeneOntologyBiologicalProcesspositive regulation of erythrocyte differentiation

ABCB10 PRMT1 PRKDC

8.54e-04371043GO:0045648
GeneOntologyBiologicalProcesscranial skeletal system development

CPLANE2 IRF6 SIX4 SIX2

8.64e-04841044GO:1904888
GeneOntologyBiologicalProcessvitamin D3 metabolic process

FGFR1 FGFR4

8.86e-0491042GO:0070640
GeneOntologyBiologicalProcesscell morphogenesis

RELN SZT2 SIPA1L3 TRIOBP DCC DSCAML1 KLF2 DST HMCN2 MACF1 IGSF9 FGFR3 PRKDC ROBO3 CNTN1

9.38e-04119410415GO:0000902
GeneOntologyBiologicalProcessprophase

TOPAZ1 SPO11

1.10e-03101042GO:0051324
GeneOntologyBiologicalProcessmeiotic prophase I

TOPAZ1 SPO11

1.10e-03101042GO:0007128
GeneOntologyBiologicalProcessregulation of phosphate transport

FGFR1 FGFR4

1.10e-03101042GO:0010966
GeneOntologyBiologicalProcesspositive regulation of chondrocyte proliferation

SIRT6 SIX2

1.10e-03101042GO:1902732
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F2 CYP4F3 CYP4F11

1.15e-03411043GO:0006691
GeneOntologyBiologicalProcesspositive regulation of animal organ morphogenesis

SIX4 FGFR1 FGFR4

1.15e-03411043GO:0110110
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

LIAS RELN CECR2 ADAMTS5 SIX4 SIRT6 SOCS7 KLF2 CITED2 CCM2 TIE1 MACF1 FGFR1 PRKDC FGFR4 SIX2 CNTN1

1.16e-03148310417GO:0048646
GeneOntologyBiologicalProcessmesoderm development

CITED2 TIE1 MACF1 FGFR1 SIX2

1.20e-031571045GO:0007498
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

SIX4 SIRT6 CITED2 TIE1 FGFR1 SIX2

1.26e-032361046GO:0061138
GeneOntologyBiologicalProcessepithelial tube morphogenesis

LIAS CECR2 SIX4 SIRT6 CITED2 CCM2 TIE1 SIX2

1.32e-034211048GO:0060562
GeneOntologyBiologicalProcessregulation of developmental growth

WWC3 SIX4 DCC CITED2 MACF1 FGFR1 FGFR3 PRKDC

1.32e-034211048GO:0048638
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F2 CYP4F11

1.34e-03111042GO:0042373
GeneOntologyBiologicalProcesspositive regulation of peroxisome proliferator activated receptor signaling pathway

CITED2 ALOX15B

1.34e-03111042GO:0035360
DomainFGF_rcpt_fam

FGFR1 FGFR3 FGFR4

6.30e-0741023IPR016248
DomainIg_I-set

DCC DSCAML1 HMCN2 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1

9.79e-071901029IPR013098
DomainI-set

DCC DSCAML1 HMCN2 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1

9.79e-071901029PF07679
DomainIGc2

DCC DSCAML1 HMCN2 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1

5.63e-062351029SM00408
DomainIg_sub2

DCC DSCAML1 HMCN2 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1

5.63e-062351029IPR003598
DomainFN3

DCC DSCAML1 TIE1 IL21R IGSF9 ROBO3 CNTN1 IL27RA

7.90e-061851028SM00060
DomainFN3

DCC DSCAML1 TIE1 IL21R IGSF9 ROBO3 CNTN1 IL27RA

1.34e-051991028PS50853
DomainFN3_dom

DCC DSCAML1 TIE1 IL21R IGSF9 ROBO3 CNTN1 IL27RA

1.92e-052091028IPR003961
DomainIg-like_fold

TGM6 DCC DSCAML1 HMCN2 TIE1 IL21R SPACA6 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1 IL27RA

2.93e-0570610214IPR013783
DomainETV3

ETV3 ETV3L

2.95e-0521022IPR032929
Domainfn3

DCC DSCAML1 TIE1 IGSF9 ROBO3 CNTN1 IL27RA

3.00e-051621027PF00041
Domain-

TGM6 DCC DSCAML1 TIE1 IL21R SPACA6 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1 IL27RA

6.48e-05663102132.60.40.10
DomainIg-like_dom

DCC DSCAML1 HMCN2 TIE1 SPACA6 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1

9.48e-0550310211IPR007110
DomainIG

DCC DSCAML1 HMCN2 TIE1 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1

1.02e-0442110210SM00409
DomainIg_sub

DCC DSCAML1 HMCN2 TIE1 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1

1.02e-0442110210IPR003599
DomainIG_LIKE

DCC DSCAML1 HMCN2 SPACA6 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1

3.53e-0449110210PS50835
Domain-

DST MACF1

4.37e-04610223.90.1290.10
DomainGAR

DST MACF1

4.37e-0461022PS51460
Domain-

DST MACF1

4.37e-04610223.30.920.20
DomainGAS_dom

DST MACF1

4.37e-0461022IPR003108
DomainGAS2

DST MACF1

4.37e-0461022PF02187
DomainGAS2

DST MACF1

4.37e-0461022SM00243
DomainPlectin_repeat

DST MACF1

6.09e-0471022IPR001101
DomainIRF-3

IRF3 IRF6

6.09e-0471022PF10401
DomainInterferon_reg_factor-3

IRF3 IRF6

6.09e-0471022IPR019471
DomainPlectin

DST MACF1

6.09e-0471022PF00681
DomainSIX1_SD

SIX4 SIX2

6.09e-0471022PF16878
DomainSIX1_SD

SIX4 SIX2

6.09e-0471022IPR031701
DomainIRF-3

IRF3 IRF6

6.09e-0471022SM01243
DomainPLEC

DST MACF1

6.09e-0471022SM00250
DomainPkinase_Tyr

TIE1 DSTYK FGFR1 FGFR3 FGFR4

7.09e-041291025PF07714
DomainKinase-like_dom

AMHR2 RIPK4 DST TIE1 DSTYK MACF1 FGFR1 FGFR3 PRKDC FGFR4

7.60e-0454210210IPR011009
DomainSer-Thr/Tyr_kinase_cat_dom

TIE1 DSTYK FGFR1 FGFR3 FGFR4

9.61e-041381025IPR001245
DomainIRF

IRF3 IRF6

1.04e-0391022SM00348
DomainInterferon_reg_fact_DNA-bd_dom

IRF3 IRF6

1.04e-0391022IPR001346
DomainIRF

IRF3 IRF6

1.04e-0391022PF00605
DomainIRF_1

IRF3 IRF6

1.04e-0391022PS00601
DomainInterferon_reg_fac_CS

IRF3 IRF6

1.04e-0391022IPR019817
DomainIRF_2

IRF3 IRF6

1.04e-0391022PS51507
DomainTyrKc

TIE1 FGFR1 FGFR3 FGFR4

1.38e-03881024SM00219
DomainTyr_kinase_cat_dom

TIE1 FGFR1 FGFR3 FGFR4

1.38e-03881024IPR020635
DomainCyt_P450_E_grp-I

CYP4F2 CYP4F3 CYP4F11

1.90e-03451023IPR002401
DomainPROTEIN_KINASE_TYR

TIE1 FGFR1 FGFR3 FGFR4

1.97e-03971024PS00109
DomainTyr_kinase_AS

TIE1 FGFR1 FGFR3 FGFR4

1.97e-03971024IPR008266
DomainSMAD_FHA_domain

IRF3 IRF6 STARD9

2.88e-03521023IPR008984
DomainCyt_P450_CS

CYP4F2 CYP4F3 CYP4F11

3.04e-03531023IPR017972
DomainSMAD_dom-like

IRF3 IRF6

3.37e-03161022IPR017855
Domain-

IRF3 IRF6

3.37e-031610222.60.200.10
DomainCYTOCHROME_P450

CYP4F2 CYP4F3 CYP4F11

3.74e-03571023PS00086
Domainig

DSCAML1 TIE1 FGFR1 FGFR3 FGFR4

3.88e-031901025PF00047
DomainImmunoglobulin

DSCAML1 TIE1 FGFR1 FGFR3 FGFR4

3.88e-031901025IPR013151
Domain-

CYP4F2 CYP4F3 CYP4F11

3.92e-035810231.10.630.10
Domainp450

CYP4F2 CYP4F3 CYP4F11

3.92e-03581023PF00067
DomainEGF_extracell

RELN SCARF1 TIE1

4.32e-03601023IPR013111
DomainEGF_2

RELN SCARF1 TIE1

4.32e-03601023PF07974
DomainCyt_P450

CYP4F2 CYP4F3 CYP4F11

4.32e-03601023IPR001128
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F11

3.20e-0512763M27129
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

3.20e-0512763M27128
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F11

3.20e-0512763MM14845
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F2 CYP4F3 CYP4F11

5.25e-0514763MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F11

6.54e-0515763M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

1.16e-0418763MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F11

1.16e-0418763MM14841
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F11

1.87e-0421763M27137
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F11 ALOX15B

2.84e-0459764M27140
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F11

3.18e-0425763MM14858
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

FGFR1 FGFR3 FGFR4

3.18e-0425763M47934
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F11 ALOX15B

3.23e-0461764MM14861
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY

FGFR1 FGFR3 FGFR4

6.07e-0431763M47396
PathwayWP_WHITE_FAT_CELL_DIFFERENTIATION

CEBPD IRF3 KLF2

6.67e-0432763M39333
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F2 CYP4F3 CYP4F11

7.31e-0433763MM15918
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F2 CYP4F3 CYP4F11

7.31e-0433763MM15963
PathwayWP_WHITE_FAT_CELL_DIFFERENTIATION

CEBPD IRF3 KLF2

7.31e-0433763MM15869
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY

FGFR1 FGFR3 FGFR4

8.71e-0435763M47379
Pubmed

Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues.

FGFR1 FGFR3 FGFR4

1.04e-07410439212826
Pubmed

FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.

FGFR1 FGFR3 FGFR4

1.04e-074104336142417
Pubmed

Immunohistochemical detection of fibroblast growth factor receptors in normal endocrine cells and related tumors of the digestive system.

FGFR1 FGFR3 FGFR4

1.04e-074104311759058
Pubmed

Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.

FGFR1 FGFR3 FGFR4

1.04e-074104312644244
Pubmed

Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.

FGFR1 FGFR3 FGFR4

1.04e-07410439664689
Pubmed

Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.

FGFR1 FGFR3 FGFR4

1.04e-074104327154171
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F11

1.04e-074104318065749
Pubmed

Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin.

FGFR1 FGFR3 FGFR4

1.04e-074104312373339
Pubmed

Large-scale deletion and point mutations of the nuclear NDUFV1 and NDUFS1 genes in mitochondrial complex I deficiency.

NDUFA8 NDUFB6 NDUFS1

1.04e-074104311349233
Pubmed

The FGF system has a key role in regulating vascular integrity.

FGFR1 FGFR3 FGFR4

1.04e-074104318776942
Pubmed

RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector.

FGFR1 FGFR3 FGFR4

1.04e-074104317304337
Pubmed

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.

FGFR1 FGFR3 FGFR4

2.59e-075104315987787
Pubmed

The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.

FGFR1 FGFR3 FGFR4

2.59e-075104327078042
Pubmed

Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.

FGFR1 FGFR3 FGFR4

2.59e-075104316091423
Pubmed

FGF-dependent regulation of VEGF receptor 2 expression in mice.

FGFR1 FGFR3 FGFR4

2.59e-075104321633168
Pubmed

Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands.

FGFR1 FGFR3 FGFR4

2.59e-075104327206683
Pubmed

Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.

FGFR1 FGFR3 FGFR4

2.59e-07510439771645
Pubmed

Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.

FGFR1 FGFR3 FGFR4

2.59e-075104328094278
Pubmed

Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands.

FGFR1 FGFR3 FGFR4

2.59e-07510439013630
Pubmed

The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.

FGFR1 FGFR3 FGFR4

2.59e-075104311566361
Pubmed

Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault.

FGFR1 FGFR3 FGFR4

5.16e-076104310572038
Pubmed

FGFR3 and FGFR4 do not mediate renal effects of FGF23.

FGFR1 FGFR3 FGFR4

5.16e-076104318753255
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F3 CYP4F11

5.16e-07610439068972
Pubmed

FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.

FGFR1 FGFR3 FGFR4

5.16e-076104319515808
Pubmed

Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1.

FGFR1 FGFR3 FGFR4

5.16e-076104324026051
Pubmed

FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells.

FGFR1 FGFR3 FGFR4

5.16e-07610439010207
Pubmed

Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains.

FGFR1 FGFR3 FGFR4

5.16e-076104316365308
Pubmed

Regulation of fibroblast growth factor-23 signaling by klotho.

FGFR1 FGFR3 FGFR4

5.16e-076104316436388
Pubmed

Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum.

FGFR1 FGFR3 FGFR4

5.16e-076104319232523
Pubmed

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.

FGFR1 FGFR3 FGFR4

5.16e-076104319966287
Pubmed

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism.

FGFR1 FGFR3 FGFR4

5.16e-076104329720668
Pubmed

FGF9 suppresses meiosis and promotes male germ cell fate in mice.

SPO11 FGFR1 FGFR3 FGFR4

5.29e-0722104420833365
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

DONSON CEBPD GTF3C4 DST ABCB10 DSTYK MACF1 FGFR3 PRKDC

7.33e-07332104937433992
Pubmed

Expression patterns of FGF receptors in the developing mammalian cochlea.

FGFR1 FGFR3 FGFR4

9.01e-077104320131355
Pubmed

FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code.

FGFR1 FGFR3 FGFR4

9.01e-077104316772167
Pubmed

Activin and basic fibroblast growth factor regulate neurogenesis of murine embryonal carcinoma cells.

FGFR1 FGFR3 FGFR4

9.01e-07710438959336
Pubmed

FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development.

RELN FGFR1 FGFR3 FGFR4

9.09e-0725104418625063
Pubmed

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.

FGFR1 FGFR3 FGFR4

1.44e-068104318187602
Pubmed

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

FGFR1 FGFR3 FGFR4

1.44e-068104317623664
Pubmed

Syndecan-4 dependent FGF stimulation of mouse vibrissae growth.

FGFR1 FGFR3 FGFR4

1.44e-068104316989989
Pubmed

Expression of Fgf receptors 1, 2, and 3 in the developing mid- and hindbrain of the mouse.

FGFR1 FGFR3 FGFR4

2.15e-069104315830353
Pubmed

Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development.

FGFR1 FGFR3 FGFR4

2.15e-069104331613912
Pubmed

Integration of FGF and TWIST in calvarial bone and suture development.

FGFR1 FGFR3 FGFR4

2.15e-069104310751173
Pubmed

The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear.

FGFR1 FGFR3 FGFR4

2.15e-069104311335076
Pubmed

Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.

FGFR1 FGFR3 FGFR4

2.15e-069104315229180
Pubmed

Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling.

FGFR1 FGFR3 FGFR4

3.07e-0610104315470137
Pubmed

Regulation of external genitalia development by concerted actions of FGF ligands and FGF receptors.

FGFR1 FGFR3 FGFR4

3.07e-0610104315340846
Pubmed

Fgf20 is required for sensory epithelial specification in the developing cochlea.

FGFR1 FGFR3 FGFR4

4.21e-0611104318524904
Pubmed

Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle.

FGFR1 FGFR3 FGFR4

4.21e-061110438901049
Pubmed

Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.

FGFR1 FGFR3 FGFR4

4.21e-0611104326906157
Pubmed

The murine gene, Traube, is essential for the growth of preimplantation embryos.

FGFR1 FGFR3 FGFR4

4.21e-0611104311071758
Pubmed

Immunohistochemical study of genesis of the mouse oral vestibule.

FGFR1 FGFR3 FGFR4

5.60e-0612104314964469
Pubmed

Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures.

FGFR1 FGFR3 FGFR4

5.60e-0612104310751172
Pubmed

Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4.

FGFR1 FGFR3 FGFR4

5.60e-0612104310918587
Pubmed

Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.

FGFR1 FGFR3 FGFR4

5.60e-0612104312460940
Pubmed

The roles of FGF signaling in germ cell migration in the mouse.

FGFR1 FGFR3 FGFR4

5.60e-0612104316291796
Pubmed

Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.

RELN TG PRKDC

7.27e-0613104322724066
Pubmed

Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2.

FGFR1 FGFR3 FGFR4

7.27e-0613104328938467
Pubmed

A quantitative method for evaluation of FGF family and FGF receptor family gene expression by RT-PCR.

FGFR1 FGFR3 FGFR4

7.27e-061310439385055
Pubmed

A point mutation in Fgf9 impedes joint interzone formation leading to multiple synostoses syndrome.

FGFR1 FGFR3 FGFR4

7.27e-0613104328169396
Pubmed

Expression of the fibroblast growth factor family and their receptor family genes during mouse brain development.

FGFR1 FGFR3 FGFR4

7.27e-061310438883961
Pubmed

Receptor specificity of the fibroblast growth factor family.

FGFR1 FGFR3 FGFR4

7.27e-061310438663044
Pubmed

Early thyroid development requires a Tbx1-Fgf8 pathway.

TG FGFR1 FGFR3

7.27e-0613104319389367
Pubmed

Sequence identity locates CEBPD and FGFR1 to mapped human loci within proximal 8p.

CEBPD FGFR1

8.86e-06210427789168
Pubmed

Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling.

FGFR1 FGFR3

8.86e-062104221779335
Pubmed

Fibroblast growth factor receptor 1 and 3 expression is associated with regulatory PI3K/AKT kinase activity, as well as invasion and prognosis, in human laryngeal cancer.

FGFR1 FGFR3

8.86e-062104229299828
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

8.86e-062104211002341
Pubmed

siRNA mediated knockdown of fibroblast growth factor receptors 1 or 3 inhibits FGF-induced anchorage-independent clonogenicity but does not affect MAPK activation.

FGFR1 FGFR3

8.86e-062104216685373
Pubmed

Oncogene mutation profiling reveals poor prognosis associated with FGFR1/3 mutation in liposarcoma.

FGFR1 FGFR3

8.86e-062104227237367
Pubmed

Disease-associated mutations in IRF6 and RIPK4 dysregulate their signalling functions.

IRF6 RIPK4

8.86e-062104225784454
Pubmed

Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3.

FGFR1 FGFR3

8.86e-06210421379594
Pubmed

Regulation of β1 integrin-Klf2-mediated angiogenesis by CCM proteins.

KLF2 CCM2

8.86e-062104225625207
Pubmed

FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung.

FGFR3 FGFR4

8.86e-06210429716527
Pubmed

Fibroblast growth factor receptors control epithelial-mesenchymal interactions necessary for alveolar elastogenesis.

FGFR3 FGFR4

8.86e-062104220093646
Pubmed

Altered expressions of fibroblast growth factor receptors and alveolarization in neonatal mice exposed to 85% oxygen.

FGFR3 FGFR4

8.86e-062104217957151
Pubmed

Role of FGF Receptors and Their Pathways in Adrenocortical Tumors and Possible Therapeutic Implications.

FGFR1 FGFR4

8.86e-062104234956100
Pubmed

Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains.

FGFR1 FGFR3

8.86e-062104211585811
Pubmed

Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis.

FGFR1 FGFR4

8.86e-062104218480409
Pubmed

RAS-MAPK Reactivation Facilitates Acquired Resistance in FGFR1-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR-MEK Blockade.

FGFR1 FGFR3

8.86e-062104229654068
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F2 CYP4F11

8.86e-062104224138531
Pubmed

Molecular characterization and mutational analysis of the human B17 subunit of the mitochondrial respiratory chain complex I.

NDUFA8 NDUFB6

8.86e-06210429760212
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

8.86e-06210428026587
Pubmed

Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation.

IRF6 RIPK4

8.86e-062104225246526
Pubmed

KLF2 regulates stemness of human mesenchymal stem cells by targeting FGFR3.

KLF2 FGFR3

8.86e-062104237381732
Pubmed

Fibroblast growth factor receptors-1 and -3 play distinct roles in the regulation of bladder cancer growth and metastasis: implications for therapeutic targeting.

FGFR1 FGFR3

8.86e-062104223468956
Pubmed

Reciprocal relationship in gene expression between FGFR1 and FGFR3: implication for tumorigenesis.

FGFR1 FGFR3

8.86e-062104215558020
Pubmed

Association of FGFR3 and FGFR4 gene polymorphisms with breast cancer in Chinese women of Heilongjiang province.

FGFR3 FGFR4

8.86e-062104226431494
Pubmed

Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas.

FGFR1 FGFR3

8.86e-062104228468611
Pubmed

Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression.

FGFR1 FGFR4

8.86e-062104222573348
Pubmed

Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation.

FGFR1 FGFR3

8.86e-062104211290300
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F3 CYP4F11

8.86e-062104215364545
Pubmed

Interferon regulatory factor 6 (IRF6) and fibroblast growth factor receptor 1 (FGFR1) contribute to human tooth agenesis.

IRF6 FGFR1

8.86e-062104217318851
Pubmed

FGF2 High Molecular Weight Isoforms Contribute to Osteoarthropathy in Male Mice.

ADAMTS5 FGFR1 FGFR3

9.23e-0614104327732085
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

DCC DSCAML1 TIE1 IGSF9 ROBO3 CNTN1

9.69e-06162104625826454
Pubmed

FGF8 is essential for formation of the ductal system in the male reproductive tract.

FGFR1 FGFR3 FGFR4

1.15e-0515104322110055
Pubmed

CDC42 is required for epicardial and pro-epicardial development by mediating FGF receptor trafficking to the plasma membrane.

FGFR1 FGFR3 FGFR4

1.15e-0515104328465335
Pubmed

Phenotypic analysis of mice completely lacking netrin 1.

DCC ROBO3 CNTN1

1.15e-0515104326395479
Pubmed

Sprouty proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development.

FGFR1 FGFR3 FGFR4

1.41e-0516104315201220
Pubmed

Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.

FGFR1 FGFR3 FGFR4

1.41e-0516104324470103
Pubmed

Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice.

FGFR1 FGFR3 FGFR4

1.41e-0516104311731698
InteractionFGF6 interactions

FGFR1 FGFR3 FGFR4

4.47e-0671033int:FGF6
InteractionFGF18 interactions

FGFR1 FGFR3 FGFR4

4.47e-0671033int:FGF18
InteractionFGF5 interactions

FGFR1 FGFR3 FGFR4

7.13e-0681033int:FGF5
InteractionFGF23 interactions

FGFR1 FGFR3 FGFR4

7.13e-0681033int:FGF23
InteractionCRLF2 interactions

CPD FGFR1 FGFR3 PRKDC FGFR4

1.50e-05611035int:CRLF2
InteractionKLB interactions

FGFR1 FGFR3 FGFR4

2.76e-05121033int:KLB
InteractionKL interactions

FGFR1 FGFR3 FGFR4

4.53e-05141033int:KL
InteractionFGF7 interactions

FGFR1 FGFR3 FGFR4

6.92e-05161033int:FGF7
InteractionFGF9 interactions

FGFR1 FGFR3 FGFR4

6.92e-05161033int:FGF9
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

DCC DSCAML1 HMCN2 IGSF9 FGFR1 FGFR3 FGFR4 ROBO3 CNTN1

5.10e-09161649593
GeneFamilyFibronectin type III domain containing

DCC DSCAML1 TIE1 IGSF9 ROBO3 CNTN1 IL27RA

1.52e-06160647555
GeneFamilyImmunoglobulin like domain containing

DCC DSCAML1 HMCN2 TIE1 IGSF9 ROBO3 CNTN1

5.26e-06193647594
GeneFamilyReceptor Tyrosine Kinases|CD molecules

TIE1 FGFR1 FGFR3 FGFR4

1.19e-0540644321
GeneFamilySINE class homeoboxes

SIX4 SIX2

1.83e-046642525
GeneFamilyCytochrome P450 family 4

CYP4F2 CYP4F3 CYP4F11

2.78e-04366431003
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

3.41e-048642939
GeneFamilyETS transcription factor family

ETV3 ETV3L

4.39e-0328642534
GeneFamilyNADH:ubiquinone oxidoreductase supernumerary subunits

NDUFA8 NDUFB6

5.03e-03306421150
CoexpressionPARENT_MTOR_SIGNALING_UP

LIAS CEBPD TRIOBP PEX6 CYP4F2 NDUFS1 CITED2 PYGL CYP4F11 TTC38 SIX2 ALDH7A1

2.65e-0656710412M16909
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RIPK4 DCC DST MACF1 FGFR3 FGFR4 CNTN1

1.07e-0716010570293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RIPK4 DCC DST MACF1 FGFR3 FGFR4 CNTN1

1.07e-0716010573eaae86fa08f7651021316f8e5811bf48055591e
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPD CPD KANSL3 GNAT3 IGSF9 ROBO3

2.84e-061671056528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPD CPD KANSL3 GNAT3 IGSF9 ROBO3

2.84e-061671056a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SH2D3A IRF6 RIPK4 FAM83C RASSF9 SIX2

4.37e-061801056255097d8eb244a32eb2ecd0e7e48e1a20bafb5cd
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF6 NXN DST TIE1 SPACA6 FGFR3

4.81e-06183105612e876d6205af8aad74265c668b5e95b9e7487f3
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SPO11 SLC22A14 FGFR4 PRDM6 SIX2

5.05e-061051055cec0bdfe2bbd87c7e84671c1eeafad17aec1cdb2
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

SPO11 SLC22A14 FGFR4 PRDM6 SIX2

5.05e-061051055c4b3f085c7e372e529d2c5d275faba403e830d48
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

SPO11 SLC22A14 FGFR4 PRDM6 SIX2

5.05e-061051055dc5f6d62945a699734a71b8ab1d4266db6fb2918
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

CITED2 DST MACF1 FGFR4 RASSF9 CNTN1

5.96e-06190105671e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell18-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

SH2D3A IRF6 RIPK4 CITED2 IGSF9 SIX2

6.52e-0619310565067b0db24f96e26cf3f9437736415f694e7a614
ToppCellBL-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IRF6 DST FGFR3 RASSF9 SIX2 ALDH7A1

6.72e-0619410562932f704656ca368565ec12f3452af3b18e8df12
ToppCellParenchyma_COVID-19-Epithelial-TX-Basal_1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SH2D3A IRF6 RIPK4 DST FGFR3 ALDH7A1

7.99e-062001056592c7c3ded409a9957cbcdc62fcc213fa8eae598
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SH2D3A IRF6 RIPK4 DST FGFR3 ALDH7A1

7.99e-0620010568cfbde43c5e66269ad128aa5398b1517667d7d36
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SH2D3A IRF6 RIPK4 DST FGFR3 ALDH7A1

7.99e-06200105661811380d9252f12f27b7ad4752380b52692677f
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPD TGM6 CCDC88B KLF2 PYGL

2.94e-051511055ced4f7ee377a23a804ae6fde624e8b55b79f1fd8
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPD TGM6 CCDC88B KLF2 PYGL

2.94e-051511055b52bb3b88e9a6473f571053537b8beb418678539
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK|Thalamus / BrainAtlas - Mouse McCarroll V32

IRF6 KLF2 TIE1 RASSF9 IL27RA

3.33e-051551055fe6c4aba0e98cda84bf178aeac2e9fa834477f22
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO4 FIGNL2 FGFR3 FGFR4 RASSF9

4.11e-0516210553a1cbfed5a063131d49e3c1584f62b12660ecb36
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO4 FIGNL2 FGFR3 FGFR4 RASSF9

4.11e-05162105504b3c38bb27fa369a9ac5b60883f8b058abc5180
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

CEBPD IL21R MACF1 FGFR3 FGFR4

4.36e-051641055519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCellfacs-Marrow-T_cells-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPD CCDC88B PYGL RASSF9 ALOX15B

4.61e-051661055fab4da2537904ad114218f720e18a600f14a00a1
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88B DSCAML1 GNAT3 PYGL CNTN1

5.17e-05170105517bd7fd25a2657cb536ad47e294332920f759e95
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN NXN TIE1 RASSF9 TMDD1

5.46e-0517210551bad7b19724e1b53ace7e05644215334c9f43910
ToppCellASK428-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

DUSP12 LIAS NXN RASSF9 ALDH7A1

5.93e-051751055e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA CECR2 CCM2 SATB1 IL21R

6.09e-0517610559b58734017ceabe81f490dd0b9f3192bc903d455
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN C8orf48 NXN DST ROBO3

6.26e-0517710558dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN C8orf48 NXN DST ROBO3

6.26e-051771055767b2af5f224d100b22bed32f86cec1cd17e8711
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5|TCGA-Lung / Sample_Type by Project: Shred V9

IRF6 FAM83C FANCE PEDS1 FGFR3

6.26e-051771055a0c7d08469c513cecf87777c19876884f1511570
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN C8orf48 NXN DST ROBO3

6.26e-0517710555ef2527e9b41e62f1724cdabaad9d8979266bb7d
ToppCellE18.5-Endothelial-Endothelial_lymphatic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN C8orf48 NXN DST ROBO3

6.26e-051771055ae1d2fdd4f67f50c906b27ea084de058c6908aa2
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRIOBP KLF2 DST TIE1 RASSF9

6.43e-0517810550139b42494c1186390b12106dea7957e2b6717c2
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA SZT2 SIPA1L3 PRKDC IL27RA

6.43e-05178105509d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM186B KLF2 SATB1 IL21R IL27RA

6.43e-05178105565508833f9f7fb03d54b62cec9a1337a06b65031
ToppCellfacs-BAT-Fat-3m-Lymphocytic-T_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CITED2 SATB1 IL21R ACOT2 IL27RA

6.43e-0517810557c101e3957ea9b0d4ebf619d1d02e7e64ae28915
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM193B FIGNL2 ZC3H6 DSTYK MACF1

6.43e-051781055c87945146b2734141f07b39d268e0d8086ee0364
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CECR2 SH2D3A RIPK4 DSCAML1 RASSF9

6.95e-051811055b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

SH2D3A IRF6 RIPK4 NXN FGFR3

6.95e-0518110556d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SPO11 FGFR4 PRDM6 IL27RA

7.57e-059510543699ea16660a22ea79fecfea56ece2dfb0f13467
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SPO11 FGFR4 PRDM6 IL27RA

7.57e-05951054cbfe615d880913bafaf5e7e8d24c3ec14a9351ce
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SPO11 FGFR4 PRDM6 IL27RA

7.57e-0595105427ac23b87747434a3084cc087e7b884e68f0eab9
ToppCellfacs-Trachea-nan-24m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN NXN SCARF1 TIE1 RASSF9

7.71e-051851055dec60254204014083ff3b4aec0cc75410950a486
ToppCellfacs-Trachea-nan-24m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN NXN SCARF1 TIE1 RASSF9

7.71e-051851055201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCellfacs-Trachea-nan-24m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN NXN SCARF1 TIE1 RASSF9

7.71e-051851055334f006c3ef33338ff8d649309d3f448733a3a99
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RELN SCARF1 TIE1 GNAT3 RASSF9

7.91e-0518610555d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RELN SCARF1 TIE1 GNAT3 RASSF9

7.91e-0518610551da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCelldroplet-Mammary_Gland-nan-21m-Lymphocytic-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA NRROS KLF2 SATB1 IL21R

8.11e-05187105516b2fddf2c23a29f173102f117876c9df5544ae4
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NDUFA8 KLF2 DST TIE1 RASSF9

8.32e-0518810555eb107122064f0a99dfd445cc87d3766f7257216
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

RELN NXN DSCAML1 TIE1 GNAT3

8.32e-051881055c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN NXN FANCE SCARF1 TIE1

8.32e-051881055524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN NXN FANCE SCARF1 TIE1

8.32e-051881055d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DCC DST FGFR4 PRDM6 CNTN1

8.53e-051891055203c80030df08ae112f9ae4043709f455d87ce89
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

IRF6 RIPK4 NXN FGFR3 ALDH7A1

8.74e-051901055ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NDUFA8 KLF2 DST TIE1 RASSF9

8.74e-051901055e1b721bb74561fe51c53328a0394c9954e489049
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

DST MACF1 FGFR4 PRDM6 CNTN1

8.74e-05190105562a3ec1ae0829602b0569cc051210551644f1d46
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CEBPD CCDC88B KLF2 PYGL CYP4F3

8.96e-051911055d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCellP07-Endothelial-large_vessel_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KLF2 DST TIE1 FGFR3 RASSF9

8.96e-051911055d162917816dd2e4767c97447c1cddae9397713ab
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

IRF6 RIPK4 NXN FGFR3 ALDH7A1

9.18e-0519210559b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CEBPD CCDC88B KLF2 PYGL CYP4F3

9.41e-051931055e1855cff9a6bcfda9188b9fdf6c9d698405da990
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

CPD RO60 NDUFS1 GTF3C4 PRKDC

9.41e-051931055abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ADAMTS5 DST FGFR4 PRDM6 CNTN1

9.41e-051931055084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CEBPD ETV3 SCARF1 SATB1 IL21R

9.41e-051931055704378de39e1b6f108ab5b0ecbd594d414ec8ae4
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CEBPD ETV3 SCARF1 SATB1 IL21R

9.64e-05194105536f8ae4f2b3bf802f6ff0e9fc79e7f170f96ae8b
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SIX4 NXN SOCS7 FGFR3 RASSF9

9.64e-0519410550cd4363627acd419e00d6d32f6dce10430aa6487
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DCC CITED2 DST MACF1 CNTN1

9.64e-05194105571d3c7448b1734de54187f902f65649f9283bd4c
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SIX4 NXN SOCS7 FGFR3 RASSF9

9.64e-051941055a58841b34efe673671a9a059238e044a7254b279
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF6 NXN CITED2 TIE1 IL27RA

9.87e-051951055df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN RAD51AP2 DST SATB1 MACF1

9.87e-0519510553e519cffa6144a62b06124642a14c9ff39b76554
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN CEBPD NXN TIE1 RASSF9

9.87e-051951055590c0dc0db4dc62879645ed7f61292ff97d2c7d5
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN RAD51AP2 DST SATB1 MACF1

9.87e-0519510557796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CITED2 DST MACF1 FGFR4 RASSF9

1.01e-0419610556730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCellfacs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPD DST MACF1 PYGL FGFR1

1.01e-04196105590edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CITED2 DST MACF1 FGFR4 RASSF9

1.01e-04196105521dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPD DST MACF1 PYGL FGFR1

1.01e-041961055c936014125b2ed5f796221b74acb77b8f8359875
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN NXN KLF2 TIE1 STARD9

1.01e-041961055b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DST MACF1 FGFR4 PRDM6 CNTN1

1.01e-0419610551450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN NXN KLF2 TIE1 STARD9

1.01e-041961055145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell3'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN NXN SCARF1 TIE1 RASSF9

1.01e-041961055aa52f77f80c3fe23369347a34e0b3188b768a763
ToppCellmild-Myeloid-Neutrophils_4|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CEBPD TUT7 INKA2 PYGL CYP4F3

1.01e-041961055f8c98cded5550843322b1711e1a57c7e88cae861
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN NXN KLF2 TIE1 STARD9

1.01e-041961055d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NXN TG HMCN2 IGSF9 SIX2

1.04e-0419710554f8f23b1ef2eae9d300bd2c1a5cb7ef0163858a1
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Basal_3|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

NXN TG HMCN2 IGSF9 SIX2

1.04e-0419710552cff37f9d33951840a8f52ccbba6ca1a4bbe3ad9
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA CEBPD WWC3 CECR2 ALOX15B

1.04e-041971055bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DST MACF1 FGFR4 PRDM6 CNTN1

1.04e-0419710550034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NXN TG HMCN2 IGSF9 SIX2

1.04e-0419710550f37afad46b94c748a149d9ee681472d7a3e6937
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DST MACF1 FGFR4 PRDM6 CNTN1

1.04e-04197105511a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF6 RIPK4 CYP4F3 FGFR3 RASSF9

1.06e-0419810559718f4c013c347f1b3c785ae232dd2fb6c1fe298
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADAMTS5 INKA2 IL21R ACOT2 PRDM6

1.06e-041981055637f11e292b90d86cdc0d0d828eb26f38289c25b
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ADAMTS5 KLF2 IL21R PRDM6

1.06e-0419810552d0c14f8cabab99bc6d7c27685437c78841c7245
ToppCell3'-Broncho-tracheal-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF6 RIPK4 DST FGFR3 ALDH7A1

1.06e-041981055aa6e7218ee6230902854e66c444b544218b30c0e
ToppCellcellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IRF6 DST IGSF9 FGFR3 SIX2

1.06e-0419810557063d74d79f53d5c59c853a2575f9d3ef12f19ea
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DST MACF1 FGFR4 PRDM6 CNTN1

1.06e-04198105517dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell5'-Adult-LymphNode-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXN SCARF1 TIE1 ROBO3 RASSF9

1.06e-041981055d7e15e61b6018e4c36461c9471ee29601929925c
ToppCell18-Distal|18 / Age, Tissue, Lineage and Cell class

CEBPD DST MACF1 PRMT1 FGFR4

1.06e-041981055d635398c6529c514e77c0dc9299e9cf00330c9e7
ToppCellTransverse-T_cell-Tcm|T_cell / Region, Cell class and subclass

FREM3 DSCAML1 KLF2 SATB1 FGFR4

1.06e-04198105562990b9ff7ca20895fed07461baba6c2caaa995e
ToppCellmedial-Epithelial-Basal|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SH2D3A IRF6 RIPK4 IGSF9 FGFR3

1.09e-041991055fa7584e3cc0f8cbdd6a76c6a0faee26b0922c4ae
ToppCellBronchial-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RELN NXN KLF2 TIE1 GNAT3

1.09e-04199105536a230b80096455df26c2e2c8c05fd6b231508c5
ToppCellmedial-Epithelial-Basal-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SH2D3A IRF6 RIPK4 IGSF9 FGFR3

1.09e-041991055fc37f8868417308fb4410684d0d1e506cec30f35
ToppCellmedial-2-Epithelial-Basal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SH2D3A IRF6 RIPK4 IGSF9 FGFR3

1.09e-04199105510af93596cc6d5da4cf5052707ff5f7fc347dc84
ToppCellwk_15-18-Mesenchymal-Fibroblast-Alveolar_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DST MACF1 FGFR4 PRDM6 CNTN1

1.09e-0419910556bce8e65859a35cfea1c210f9c9765952d492ed2
Drug3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea

FGFR1 FGFR3 FGFR4

3.69e-0741043ctd:C568950
Drugdichloran

FMO4 CYP4F2 TGM6 CYP4F3 CYP4F11

1.19e-06411045CID000007430
DrugPalifermin

FGFR1 FGFR3 FGFR4

1.83e-0661043DB00039
Diseasebone disease (implicated_via_orthology)

FGFR1 FGFR3 FGFR4

3.99e-0751023DOID:0080001 (implicated_via_orthology)
DiseasePopliteal pterygium syndrome

IRF6 RIPK4

1.18e-0521022cv:C0265259
Diseasepopliteal pterygium syndrome (implicated_via_orthology)

IRF6 RIPK4

1.18e-0521022DOID:0060055 (implicated_via_orthology)
DiseaseGaze Palsy, Familial Horizontal, with Progressive Scoliosis

DCC ROBO3

1.18e-0521022C1846496
DiseaseGAZE PALSY, FAMILIAL HORIZONTAL, WITH PROGRESSIVE SCOLIOSIS, 1

DCC ROBO3

1.18e-0521022C4551964
DiseaseTWIST1-related craniosynostosis

FGFR1 FGFR3

7.07e-0541022cv:C4551902
DiseaseCraniosynostosis syndrome

FGFR1 FGFR3

2.46e-0471022cv:C0010278
Diseaseoctadecanedioylcarnitine (C18-DC) measurement

CYP4F2 ACOT2

2.46e-0471022EFO_0800371
Diseasecleft palate (implicated_via_orthology)

PRMT1 SIX2

3.27e-0481022DOID:674 (implicated_via_orthology)
DiseaseCleft upper lip

IRF6 FGFR1 FGFR3

3.35e-04391023C0008924
DiseaseMelancholia

RELN TG FGFR1

3.89e-04411023C0025193
DiseaseDepression, Neurotic

RELN TG FGFR1

3.89e-04411023C0282126
DiseaseColorectal Neoplasms

DONSON DCC NXN KLF2 ABCB10 FGFR3

4.11e-042771026C0009404
DiseaseCleft palate, isolated

IRF6 FGFR1 FGFR3

4.17e-04421023C1837218
DiseaseDepressive Syndrome

RELN TG FGFR1

4.17e-04421023C0086133
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

4.19e-0491022EFO_0800562
Diseasehigh grade glioma (implicated_via_orthology)

FGFR1 FGFR3 FGFR4

4.79e-04441023DOID:3070 (implicated_via_orthology)
DiseaseEndogenous depression

RELN TG FGFR1

5.46e-04461023C0011573
Diseasebrain measurement, neuroimaging measurement

TRIOBP DCC DSCAML1 TG DSTYK MACF1 IGSF9 FGFR3

6.56e-045501028EFO_0004346, EFO_0004464
DiseaseColorectal Carcinoma

DONSON DCC NXN DSCAML1 NCDN KLF2 ABCB10 FGFR3 CNTN1

7.43e-047021029C0009402
DiseaseOligodontia

IRF6 FGFR1

7.64e-04121022C4082304
Diseasehypothyroidism (implicated_via_orthology)

TG CS

9.00e-04131022DOID:1459 (implicated_via_orthology)
DiseaseHypodontia

IRF6 FGFR1

1.05e-03141022C0020608
Diseaseneuroimaging measurement

RELN SZT2 DCC NDUFA8 TG CCM2 DSTYK MACF1 IGSF9 FGFR3 ROBO3

1.18e-03106910211EFO_0004346
Diseasecleft lip (is_implicated_in)

IRF6 FGFR1

1.21e-03151022DOID:9296 (is_implicated_in)
Diseaseeosinophil percentage of granulocytes

DOCK3 CEBPD KLF2 KANSL3 PRKDC

1.34e-032341025EFO_0007996
Diseasegliosarcoma

FGFR1 FGFR3

1.38e-03161022C0206726
DiseaseBrachycephaly

FGFR1 FGFR3

1.56e-03171022C0221356
Diseaseresponse to methotrexate, neurotoxicity

NXN MACF1

1.95e-03191022EFO_0011057, GO_0031427
DiseaseSevere Combined Immunodeficiency

IL21R PRKDC

2.16e-03201022C0085110
Diseasecortical surface area measurement

AMHR2 RELN CALHM1 TUT7 TRIOBP TG DSTYK MACF1 IGSF9 FGFR1 FGFR3 PRDM6

2.35e-03134510212EFO_0010736
DiseaseCleft Palate

IRF6 FGFR1 FGFR3

2.81e-03811023C0008925
Diseasecleft lip

SH2D3A IRF6 DST FGFR4 RASSF9

3.11e-032841025EFO_0003959
DiseaseDwarfism

DONSON TG

3.37e-03251022C0013336
DiseaseInvolutional paraphrenia

RELN FREM3

3.37e-03251022C1571983
DiseasePsychosis, Involutional

RELN FREM3

3.37e-03251022C1571984
DiseaseInvolutional Depression

RELN FREM3

3.37e-03251022C0011574

Protein segments in the cluster

PeptideGeneStartEntry
RRPKPWEAAALAESL

C6orf226

56

Q5I0X4
EEEEPPLWLEKRFLR

CCDC88B

41

A6NC98
IWADIPAPKRGEIVR

ALDH7A1

101

P49419
KPLLRGPWAEEEKGR

ADAMTS5

166

Q9UNA0
PPKLRLKRRWNDDPE

ETV3

471

P41162
LDPLWEFPRDRLVLG

FGFR4

456

P22455
AGGRLWELLEREPKL

ABCB10

461

Q9NRK6
WELLEREPKLPFNEG

ABCB10

466

Q9NRK6
GLLWALEPEKPLVRL

ACOT2

141

P49753
EWKRPLGRRAKDPAV

CALHM1

81

Q8IU99
KLAWRDGEDIILRVP

CCM2

121

Q9BSQ5
WRDLEKAELSLVPAP

FAM186B

566

Q8IYM0
RAWLLAQGKELPPEL

CECR2

401

Q9BXF3
LLWEILSRCPDLRPD

AMHR2

416

Q16671
RDKWLAPDGLIFPDR

PRMT1

181

Q99873
KAGWRLPLVPRLSEA

RAD51AP2

46

Q09MP3
EKWRGSERVLPPLTR

RASSF9

81

O75901
FPRLSDDPRIIWKRL

C8orf48

251

Q96LL4
RKGSQKDLRPPDLWI

DCC

1141

P43146
DLWKPLPQERDRLPS

KRBA1

661

A5PL33
PQLAEVIKRLWRDPG

GNAT3

121

A8MTJ3
WKEAEPDLLAVLRGL

NCDN

211

Q9UBB6
DRDRLLKEKPGWVTP

INKA2

221

Q9NTI7
LLELVPWRAREGLEK

DST

5786

Q03001
IVLAGRPLPERHWLK

HMCN2

906

Q8NDA2
PDLLPDWPLERLGRV

FAM43B

41

Q6ZT52
KEDDALWPPPDRVGR

MAGOH

71

P61326
ESPRLPNPLWDRGKI

LBHD1

26

Q9BQE6
EILEGSPEKLPRWRE

PEX6

366

Q13608
RWLKDQELSPREPVL

NDUFB6

21

O95139
SIPLLFLKDPRLAWE

FMO4

446

P31512
ARDGDPLEKLNWVRL

IL27RA

356

Q6UWB1
REELAPLVGPTLWRL

IL27RA

411

Q6UWB1
PLEKIGFWRRLEDLI

PEDS1

236

A5PLL7
LLELVPWRAREGLDK

MACF1

1756

O94854
GERLRLPPWLKTEIP

LIAS

71

O43766
EACWDGDPLKRPLLG

DSTYK

886

Q6XUX3
ELVPWRAREGLDKLV

MACF1

5631

Q9UPN3
LLPPDAKEIATRFRW

RELN

2626

P78509
ELPEWLRDLPREVCL

PRDM6

236

Q9NQX0
AWELPLLRVKSVPGR

CPLANE2

196

Q9BU20
RWGEIIKLPIPIDRF

DOCK3

486

Q8IZD9
PRLLKREPDWGDGDA

CEBPD

116

P49716
PARERLLEWPDRELD

FAM193B

531

Q96PV7
WELPRDRLVLGKPLG

FGFR1

471

P11362
AIRWLKDGRPLPADS

DSCAML1

256

Q8TD84
AGPLRGRVEELKLPW

FAM83C

16

Q9BQN1
KLALWDRRPDTTAPL

COG3

21

Q96JB2
LIWSRALGFPLERPK

CS

436

O75390
KPELILRAEGGLWLR

CYP4F11

501

Q9HBI6
LGNPVPDIRWRKVLE

CNTN1

266

Q12860
DERPPWRLGRLLLLM

CPD

6

O75976
KPELVLRAEGGLWLR

CYP4F2

501

P78329
LSWLPLFPRIGADRK

DONSON

226

Q9NYP3
GAEALSLLLKRPWDP

KANSL3

241

Q9P2N6
LDRLKPPLADGEDWA

IL21R

446

Q9HBE5
KPELVLRAEGGLWLR

CYP4F3

501

Q08477
KAALEEELVWPLLRP

FIGNL2

401

A6NMB9
APDPDAWLRALGELL

FANCE

126

Q9HB96
PEGKRVPKRLRCWEE

FANCE

211

Q9HB96
ELELPADPKWELSRA

FGFR3

456

P22607
WLLSLRPEGLEVKPA

ETV3L

301

Q6ZN32
WRLFVPALDKPETDL

DUSP12

76

Q9UNI6
FLPEGEDGLRLKWPR

SLC22A14

456

Q9Y267
EDGLRLKWPRCPATE

SLC22A14

461

Q9Y267
WRPSLGELLARPEAL

SPACA6

276

W5XKT8
VLDKLGWVRPDLGEL

NDUFA8

111

P51970
GVPRDCKWERLDLGL

NRROS

636

Q86YC3
LWRRKKDPIGPLEHR

OR4D5

301

Q8NGN0
PLKRLLVPGEEWEFE

IRF3

191

Q14653
GEEWPDGKPLERKLI

IRF6

376

O14896
ALWLLSKEPGDQRPL

ALOX15B

606

O15296
VPLGRSLWLDPLRDL

FREM3

71

P0C091
PGAREEPWLKELSLA

SZT2

2901

Q5T011
DTLWKRLFLLEPPGP

SZT2

3276

Q5T011
LLVIRDDPEGLEFPW

NXN

151

Q6DKJ4
TPPGLAREDWKIIRA

NDUFS1

611

P28331
AVRFLDLPWEDVLLP

FBXL15

16

Q9H469
ARVADWPPKREALRE

SIPA1L3

81

O60292
RRKFPLPRTIWDGEE

SIX4

211

Q9UIU6
GLSPLLWKERRALEE

STARD9

616

Q9P2P6
RDEPLDSLASPIRWK

MROH2B

791

Q7Z745
GLRGKLKWRPDEEIL

RO60

336

P10155
PPEELERKVWELARL

SIRT6

26

Q8N6T7
KLLASEPLPWDLRFR

RIPK4

106

P57078
WAPRSDLKDRPARDG

SCARF1

446

Q14162
ELDWRDLLGLLRAPG

TRIOBP

1556

Q9H2D6
LLRWKEDPSPENRTL

SATB1

531

Q01826
GLDRIKELPELWLGQ

CITED2

236

Q99967
KPDVILKLERGEEPW

ZNF567

51

Q8N184
PLDLRLAWDPRKLRG

ZC3H6

776

P61129
PAIRWLGLLPSDLKR

SPO11

306

Q9Y5K1
DGPARIEPLRARKWS

SH2D3A

131

Q9BRG2
AWGPPLLLEKDDRIV

TIE1

56

P35590
VKGDPPPRLRWRKED

ROBO3

281

Q96MS0
PPRLRWRKEDGELPT

ROBO3

286

Q96MS0
QLRWDRDEGPPPAKL

nan

266

A8MX80
LLLPKERRAPPGAWA

TMDD1

271

P0DPE3
DRDLILKWPGPERAL

PPP1R3F

531

Q6ZSY5
RHPAPEDPDWIKRLL

GTF3C4

796

Q9UKN8
DWTLRERLLPGLLPA

IGSF9

1001

Q9P2J2
ELLSRADLELPWRPL

PSME4

131

Q14997
VRRKFPLPRSIWDGE

SIX2

111

Q9NPC8
DPKALPPGLALERTW

SOCS7

36

O14512
RGKARLPPDVLRWVE

PRKDC

2911

P78527
LRELPVLDCGWIKPD

TOPAZ1

921

Q8N9V7
PLRDCQAWKDARLPL

TTC38

6

Q5R3I4
DLGREKILRPPVEKW

TUT7

1426

Q5VYS8
LPEALERWPVDLVEK

PYGL

381

P06737
ERWPVDLVEKLLPRH

PYGL

386

P06737
PPARALKRSLWVEVD

TG

2491

P01266
LWRDDLLEPATKPSI

TGM6

481

O95932
TDLPPWVLRDERLRG

WWC3

1006

Q9ULE0
ELLEAKPKRGRRSWP

KLF2

251

Q9Y5W3
LNLLRGWREPAELPK

NAPSA

41

O96009