Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	kinase activity	CERKL CDC42BPG AXL NTRK3 DGKZ LRRK1 STK32C MAP3K3 ULK3 PIK3CB MAST1 PAK3 DGKI PRKCH RIOK2	5.20e-06	764	99	15	GO:0016301
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDC42BPG AXL NTRK3 DGKZ LRRK1 STK32C MAP3K3 ULK3 PIK3CB MAST1 PAK3 DGKI PRKCH RIOK2	1.04e-05	709	99	14	GO:0016773
GeneOntologyMolecularFunction	protein serine kinase activity	CDC42BPG LRRK1 STK32C MAP3K3 ULK3 PIK3CB MAST1 PAK3 PRKCH RIOK2	1.29e-05	363	99	10	GO:0106310
GeneOntologyMolecularFunction	protein kinase activity	CDC42BPG AXL NTRK3 LRRK1 STK32C MAP3K3 ULK3 PIK3CB MAST1 PAK3 PRKCH RIOK2	4.14e-05	600	99	12	GO:0004672
GeneOntologyMolecularFunction	lipid kinase activity	CERKL DGKZ PIK3CB DGKI	5.00e-05	41	99	4	GO:0001727
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CERKL CDC42BPG AXL NTRK3 DGKZ LRRK1 STK32C MAP3K3 ULK3 PIK3CB MAST1 PAK3 DGKI PRKCH RIOK2	5.73e-05	938	99	15	GO:0016772
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDC42BPG LRRK1 STK32C MAP3K3 ULK3 PIK3CB MAST1 PAK3 PRKCH RIOK2	7.39e-05	446	99	10	GO:0004674
GeneOntologyMolecularFunction	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	KDM5C KDM5D	3.60e-04	6	99	2	GO:0034647
GeneOntologyMolecularFunction	histone H3K4 demethylase activity	KDM5C KDM5D	6.68e-04	8	99	2	GO:0032453
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK1 DOCK4 DOCK10 ARHGAP11A FAM13B ELMO1 DGKI ARHGEF4 ARHGAP20	9.35e-04	507	99	9	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK1 DOCK4 DOCK10 ARHGAP11A FAM13B ELMO1 DGKI ARHGEF4 ARHGAP20	9.35e-04	507	99	9	GO:0030695
GeneOntologyMolecularFunction	ATP-dependent diacylglycerol kinase activity	DGKZ DGKI	1.30e-03	11	99	2	GO:0004143
GeneOntologyMolecularFunction	phosphoric diester hydrolase activity	PDE6B PLCB3 PLCG2 PLD2	1.38e-03	97	99	4	GO:0008081
GeneOntologyBiologicalProcess	small GTPase-mediated signal transduction	DOCK1 DOCK4 DOCK10 DGKZ ARHGAP11A FAM13B ELMO1 PIK3CB DGKI ARHGEF4 PLD2 ARHGAP20	1.15e-05	538	100	12	GO:0007264
Domain	PH_dom-like	CDC42BPG VEPH1 DOCK10 ELMO1 OSBPL3 PLCB3 PLCG2 ARHGEF4 FRMPD3 PLD2 ARHGAP20 FRMD5	2.62e-06	426	99	12	IPR011993
Domain	-	CDC42BPG VEPH1 DOCK10 ELMO1 OSBPL3 PLCB3 PLCG2 ARHGEF4 PLD2 ARHGAP20 FRMD5	7.13e-06	391	99	11	2.30.29.30
Domain	PH	CDC42BPG VEPH1 DOCK10 ELMO1 OSBPL3 PLCG2 ARHGEF4 PLD2 ARHGAP20	1.69e-05	278	99	9	SM00233
Domain	PH_DOMAIN	CDC42BPG VEPH1 DOCK10 ELMO1 OSBPL3 PLCG2 ARHGEF4 PLD2 ARHGAP20	1.74e-05	279	99	9	PS50003
Domain	PH_domain	CDC42BPG VEPH1 DOCK10 ELMO1 OSBPL3 PLCG2 ARHGEF4 PLD2 ARHGAP20	1.79e-05	280	99	9	IPR001849
Domain	DHR-1_domain	DOCK1 DOCK4 DOCK10	2.31e-05	11	99	3	IPR027007
Domain	DHR_2	DOCK1 DOCK4 DOCK10	2.31e-05	11	99	3	PS51651
Domain	DHR_1	DOCK1 DOCK4 DOCK10	2.31e-05	11	99	3	PS51650
Domain	DHR-2	DOCK1 DOCK4 DOCK10	2.31e-05	11	99	3	PF06920
Domain	DOCK	DOCK1 DOCK4 DOCK10	2.31e-05	11	99	3	IPR026791
Domain	DOCK_C	DOCK1 DOCK4 DOCK10	2.31e-05	11	99	3	IPR010703
Domain	DOCK-C2	DOCK1 DOCK4 DOCK10	2.31e-05	11	99	3	PF14429
Domain	DHR-2	DOCK1 DOCK4 DOCK10	2.31e-05	11	99	3	IPR027357
Domain	C1	CDC42BPG DGKZ KMT2C DGKI PRKCH	2.43e-05	65	99	5	SM00109
Domain	PE/DAG-bd	CDC42BPG DGKZ KMT2C DGKI PRKCH	2.61e-05	66	99	5	IPR002219
Domain	Kinase-like_dom	CDC42BPG AXL NTRK3 LRRK1 STK32C MAP3K3 ULK3 PIK3CB MAST1 PAK3 PRKCH RIOK2	2.94e-05	542	99	12	IPR011009
Domain	Prot_kinase_dom	CDC42BPG AXL NTRK3 LRRK1 STK32C MAP3K3 ULK3 MAST1 PAK3 PRKCH RIOK2	5.60e-05	489	99	11	IPR000719
Domain	PROTEIN_KINASE_DOM	CDC42BPG AXL NTRK3 LRRK1 STK32C MAP3K3 ULK3 MAST1 PAK3 PRKCH RIOK2	6.03e-05	493	99	11	PS50011
Domain	Diacylglycerol_kinase_cat_dom	CERKL DGKZ DGKI	6.28e-05	15	99	3	IPR001206
Domain	DAGK	CERKL DGKZ DGKI	6.28e-05	15	99	3	PS50146
Domain	DAGK_cat	CERKL DGKZ DGKI	6.28e-05	15	99	3	PF00781
Domain	NAD/diacylglycerol_kinase	CERKL DGKZ DGKI	9.31e-05	17	99	3	IPR016064
Domain	SANT	MIER2 CHD7 MIER1 MYPOP	1.42e-04	50	99	4	SM00717
Domain	PROTEIN_KINASE_ATP	CDC42BPG AXL NTRK3 LRRK1 STK32C MAP3K3 ULK3 MAST1 PAK3 PRKCH	1.61e-04	459	99	10	PS00107
Domain	SANT/Myb	MIER2 CHD7 MIER1 MYPOP	1.65e-04	52	99	4	IPR001005
Domain	Lys_sp_deMease-like_dom	KDM5C KDM5D	1.66e-04	4	99	2	IPR013637
Domain	PLU-1	KDM5C KDM5D	1.66e-04	4	99	2	PF08429
Domain	PH	CDC42BPG VEPH1 DOCK10 OSBPL3 PLCG2 ARHGEF4 PLD2	2.17e-04	229	99	7	PF00169
Domain	C1_1	CDC42BPG DGKZ DGKI PRKCH	2.37e-04	57	99	4	PF00130
Domain	DOCK_N	DOCK1 DOCK4	2.75e-04	5	99	2	PF16172
Domain	DOCK_N	DOCK1 DOCK4	2.75e-04	5	99	2	IPR032376
Domain	zf-C5HC2	KDM5C KDM5D	2.75e-04	5	99	2	PF02928
Domain	Znf_C5HC2	KDM5C KDM5D	2.75e-04	5	99	2	IPR004198
Domain	ZF_DAG_PE_1	CDC42BPG DGKZ DGKI PRKCH	3.70e-04	64	99	4	PS00479
Domain	ZF_DAG_PE_2	CDC42BPG DGKZ DGKI PRKCH	3.70e-04	64	99	4	PS50081
Domain	Ser/Thr_kinase_AS	CDC42BPG LRRK1 STK32C MAP3K3 ULK3 MAST1 PAK3 PRKCH	6.22e-04	357	99	8	IPR008271
Domain	S_TKc	CDC42BPG LRRK1 STK32C MAP3K3 ULK3 MAST1 PAK3 PRKCH	6.45e-04	359	99	8	SM00220
Domain	PHD	KDM5C KDM5D TRIM66 KMT2C	6.77e-04	75	99	4	PF00628
Domain	PROTEIN_KINASE_ST	CDC42BPG LRRK1 STK32C MAP3K3 ULK3 MAST1 PAK3 PRKCH	6.81e-04	362	99	8	PS00108
Domain	Znf_PHD-finger	KDM5C KDM5D TRIM66 KMT2C	8.23e-04	79	99	4	IPR019787
Domain	Pkinase	CDC42BPG LRRK1 STK32C MAP3K3 ULK3 MAST1 PAK3 PRKCH	9.49e-04	381	99	8	PF00069
Domain	SH3	DOCK1 DOCK4 MIA3 SAMSN1 PLCG2 ARHGEF4	1.02e-03	216	99	6	SM00326
Domain	SH3	DOCK1 DOCK4 MIA3 SAMSN1 PLCG2 ARHGEF4	1.02e-03	216	99	6	PS50002
Domain	SH3_domain	DOCK1 DOCK4 MIA3 SAMSN1 PLCG2 ARHGEF4	1.12e-03	220	99	6	IPR001452
Domain	DAGK_acc	DGKZ DGKI	1.22e-03	10	99	2	PF00609
Domain	JmjN	KDM5C KDM5D	1.22e-03	10	99	2	SM00545
Domain	Diacylglycerol_kin_accessory	DGKZ DGKI	1.22e-03	10	99	2	IPR000756
Domain	JmjN	KDM5C KDM5D	1.22e-03	10	99	2	PF02375
Domain	JMJN	KDM5C KDM5D	1.22e-03	10	99	2	PS51183
Domain	DAGKa	DGKZ DGKI	1.22e-03	10	99	2	SM00045
Domain	JmjN	KDM5C KDM5D	1.22e-03	10	99	2	IPR003349
Domain	PHD	KDM5C KDM5D TRIM66 KMT2C	1.28e-03	89	99	4	SM00249
Domain	Znf_PHD	KDM5C KDM5D TRIM66 KMT2C	1.39e-03	91	99	4	IPR001965
Domain	Pkinase_C	CDC42BPG MAST1 PRKCH	1.43e-03	42	99	3	PF00433
Domain	ZF_PHD_2	KDM5C KDM5D TRIM66 KMT2C	1.63e-03	95	99	4	PS50016
Domain	ZF_PHD_1	KDM5C KDM5D TRIM66 KMT2C	1.70e-03	96	99	4	PS01359
Domain	ELM2_dom	MIER2 MIER1	2.09e-03	13	99	2	IPR000949
Domain	ELM2	MIER2 MIER1	2.09e-03	13	99	2	PF01448
Domain	ELM2	MIER2 MIER1	2.09e-03	13	99	2	PS51156
Domain	ELM2	MIER2 MIER1	2.09e-03	13	99	2	SM01189
Domain	DAGKc	DGKZ DGKI	2.43e-03	14	99	2	SM00046
Domain	-	KDM5C KDM5D	2.79e-03	15	99	2	1.10.150.60
Domain	BRIGHT	KDM5C KDM5D	2.79e-03	15	99	2	SM00501
Domain	EF-hand_like	PLCB3 PLCG2	2.79e-03	15	99	2	PF09279
Domain	ARID_dom	KDM5C KDM5D	2.79e-03	15	99	2	IPR001606
Domain	ARID	KDM5C KDM5D	2.79e-03	15	99	2	PS51011
Domain	PI-PLC-Y	PLCB3 PLCG2	2.79e-03	15	99	2	PF00387
Domain	PLCYc	PLCB3 PLCG2	2.79e-03	15	99	2	SM00149
Domain	PLipase_C_Pinositol-sp_Y	PLCB3 PLCG2	2.79e-03	15	99	2	IPR001711
Domain	PIPLC_Y_DOMAIN	PLCB3 PLCG2	2.79e-03	15	99	2	PS50008
Domain	ARID	KDM5C KDM5D	2.79e-03	15	99	2	PF01388
Domain	PI-PLC_fam	PLCB3 PLCG2	2.79e-03	15	99	2	IPR001192
Domain	PLC_EF-hand-like	PLCB3 PLCG2	2.79e-03	15	99	2	IPR015359
Domain	Ubiquitin-rel_dom	DDI2 PIK3CB FRMPD3 ARHGAP20 FRMD5	2.98e-03	184	99	5	IPR029071
Domain	AGC-kinase_C	CDC42BPG MAST1 PRKCH	3.27e-03	56	99	3	IPR000961
Domain	AGC_KINASE_CTER	CDC42BPG MAST1 PRKCH	3.27e-03	56	99	3	PS51285
Domain	S_TK_X	CDC42BPG MAST1 PRKCH	3.27e-03	56	99	3	SM00133
Domain	PBD	CDC42BPG PAK3	3.59e-03	17	99	2	PF00786
Domain	bHLH_dom	CDC42BPG MAX ARNT2 ASCL4	3.59e-03	118	99	4	IPR011598
Domain	PI-PLC-X	PLCB3 PLCG2	4.03e-03	18	99	2	PF00388
Domain	PLCXc	PLCB3 PLCG2	4.03e-03	18	99	2	SM00148
Domain	Protein_kinase_ATP_BS	CDC42BPG AXL NTRK3 STK32C ULK3 PAK3 PRKCH	4.04e-03	379	99	7	IPR017441
Domain	RhoGAP	ARHGAP11A FAM13B ARHGAP20	4.36e-03	62	99	3	SM00324
Domain	PIPLC_X_DOMAIN	PLCB3 PLCG2	4.48e-03	19	99	2	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	PLCB3 PLCG2	4.48e-03	19	99	2	IPR000909
Domain	RhoGAP	ARHGAP11A FAM13B ARHGAP20	4.56e-03	63	99	3	PF00620
Domain	RhoGAP_dom	ARHGAP11A FAM13B ARHGAP20	4.76e-03	64	99	3	IPR000198
Domain	RHOGAP	ARHGAP11A FAM13B ARHGAP20	4.76e-03	64	99	3	PS50238
Domain	-	ARHGAP11A FAM13B ARHGAP20	4.76e-03	64	99	3	1.10.555.10
Domain	CRIB	CDC42BPG PAK3	4.97e-03	20	99	2	PS50108
Domain	Zinc_finger_PHD-type_CS	KDM5C KDM5D TRIM66	4.97e-03	65	99	3	IPR019786
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK1 DOCK4 DOCK10 FAM13B PAK3 ARHGEF4 PLD2 ARHGAP20	5.23e-06	184	74	8	M41809
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK1 DOCK4 DOCK10 FAM13B PAK3 PLD2 ARHGAP20	3.60e-05	175	74	7	MM15599
Pathway	KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM	DGKZ PIK3CB DGKI PLCB3 PLCG2	4.80e-05	76	74	5	M9052
Pathway	REACTOME_SIGNALING_BY_VEGF	DOCK1 AXL ELMO1 PIK3CB PAK3	2.04e-04	103	74	5	MM14752
Pathway	REACTOME_SIGNALING_BY_VEGF	DOCK1 AXL ELMO1 PIK3CB PAK3	2.33e-04	106	74	5	M27077
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGB1_TO_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY	DOCK1 ELMO1	2.69e-04	5	74	2	M48982
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	DGKZ DGKI PRKCH	2.94e-04	25	74	3	MM14511
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	DOCK1 ELMO1 PIK3CB PLCG2 PLD2	3.27e-04	114	74	5	MM14814
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	DGKZ DGKI PRKCH	3.71e-04	27	74	3	M12123
Pathway	WP_MAPK_CASCADE	MBP MAP3K3 PLCB3	4.14e-04	28	74	3	MM15976
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK1 DOCK4 DOCK10 ARHGAP11A FAM13B PAK3 ARHGEF4 PLD2 ARHGAP20	5.58e-04	450	74	9	M27078
Pathway	WP_MAPK_CASCADE	MBP MAP3K3 PLCB3	6.77e-04	33	74	3	M39594
Pathway	WP_RESISTIN_AS_A_REGULATOR_OF_INFLAMMATION	PIK3CB PLCB3 PLCG2	6.77e-04	33	74	3	M39745
Pathway	PID_IL8_CXCR2_PATHWAY	ELMO1 PLCB3 PLD2	7.39e-04	34	74	3	M210
Pathway	WP_ALSTROM_SYNDROME	ACTN4 CEP192 ALMS1	7.39e-04	34	74	3	M45524
Pathway	REACTOME_HEMOSTASIS	DOCK1 DOCK4 DOCK10 DGKZ ACTN4 PIK3CB DGKI PRKCH PPIL2 PLCG2	7.64e-04	571	74	10	MM14472
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	DOCK4 DYNC2H1 CCDC174 KDM5C MAX ZDBF2 CHD7 CEP192 RAD54L2 ALMS1 PPIL2 DSCC1 HDLBP	1.50e-08	588	100	13	38580884
Pubmed	A human MAP kinase interactome.	DOCK1 MAX ACTN4 STK32C FAM13B MAP3K3 KMT2C PAK3 PRKCH ARHGEF4 CUX1 HDLBP	1.67e-08	486	100	12	20936779
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MIA3 DDI2 DGKZ ACTN4 CHD7 CEP192 THOC2 MIER1 MAP3K3 KMT2C POLR3D OSBPL3 VCAN GFPT2 CNOT2	4.93e-07	1084	100	15	11544199
Pubmed	CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly.	RBM12B CEP192 ALMS1	2.73e-06	10	100	3	22895009
Pubmed	Human transcription factor protein interaction networks.	HSPG2 LIMA1 CCDC174 MAX CHD7 CEP192 RAD54L2 MIER1 KMT2C FAT1 ALMS1 YLPM1 PPIL2 GFPT2 CNOT2 CUX1	3.15e-06	1429	100	16	35140242
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CCDC174 MAX ACTN4 CHD7 RAD54L2 PRC1 THOC2 ELMO1 ACTR1A KMT2C PPIL2 MED23 CUX1 HDLBP	3.35e-06	1103	100	14	34189442
Pubmed	Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1.	MBP MAP3K3 USP2	4.98e-06	12	100	3	24975362
Pubmed	The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.	DOCK1 DOCK4 ELMO1	6.46e-06	13	100	3	21930703
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KDM5C KDM5D KMT2C	6.46e-06	13	100	3	24619213
Pubmed	Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery.	DOCK1 ELMO1	8.18e-06	2	100	2	17173036
Pubmed	Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.	KDM5C KDM5D	8.18e-06	2	100	2	10441747
Pubmed	Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.	KDM5C KDM5D	8.18e-06	2	100	2	16416087
Pubmed	Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration.	DOCK1 ELMO1	8.18e-06	2	100	2	14638695
Pubmed	Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.	KDM5C KDM5D	8.18e-06	2	100	2	32081420
Pubmed	Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.	KDM5C KDM5D	8.18e-06	2	100	2	9060413
Pubmed	[Association of single nucleotide polymorphisms of CSPG2 and HSPG2 genes with intracranial aneurysm in ethnic Han Chinese population].	HSPG2 VCAN	8.18e-06	2	100	2	23568740
Pubmed	Increased NG2(+) glial cell proliferation and oligodendrocyte generation in the hypomyelinating mutant shiverer.	MBP VCAN	8.18e-06	2	100	2	15326615
Pubmed	Elmo1 inhibits ubiquitylation of Dock180.	DOCK1 ELMO1	8.18e-06	2	100	2	16495483
Pubmed	A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.	KDM5C KDM5D	8.18e-06	2	100	2	7524912
Pubmed	The intracranial aneurysm susceptibility genes HSPG2 and CSPG2 are not associated with abdominal aortic aneurysm.	HSPG2 VCAN	8.18e-06	2	100	2	20053631
Pubmed	Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.	DOCK1 DOCK4 DOCK10	8.20e-06	14	100	3	12432077
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CDC42BPG MIA3 PARG DOCK10 RAD54L2 CUL5 OSBPL3 CHPF2 PLCB3 RIOK2	1.86e-05	650	100	10	38777146
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	HSPG2 MIA3 RBM12B ACTN4 YLPM1	2.40e-05	118	100	5	21078624
Pubmed	Genetic mapping demonstrates that the alpha-subunit of retinal cGMP-phosphodiesterase is not the site of the rd mutation.	PDE6B MBP	2.45e-05	3	100	2	2167232
Pubmed	Diacylglycerol Kinase ζ (DGKζ) Is a Critical Regulator of Bone Homeostasis Via Modulation of c-Fos Levels in Osteoclasts.	DGKZ PLCG2	2.45e-05	3	100	2	25891971
Pubmed	Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development.	HSPG2 VCAN	2.45e-05	3	100	2	19669783
Pubmed	PH domain of ELMO functions in trans to regulate Rac activation via Dock180.	DOCK1 ELMO1	2.45e-05	3	100	2	15247908
Pubmed	Identification of a mouse male-specific transplantation antigen, H-Y.	KDM5C KDM5D	2.45e-05	3	100	2	7544442
Pubmed	Annexin A2 interacting with ELMO1 regulates HCC chemotaxis and metastasis.	DOCK1 ELMO1	2.45e-05	3	100	2	30853625
Pubmed	BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module.	DOCK1 ELMO1	2.45e-05	3	100	2	17960134
Pubmed	The DOCK180/Elmo complex couples ARNO-mediated Arf6 activation to the downstream activation of Rac1.	DOCK1 ELMO1	2.45e-05	3	100	2	16213822
Pubmed	The bipartite rac1 Guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (elmo1/dock180) protects endothelial cells from apoptosis in blood vessel development.	DOCK1 ELMO1	2.45e-05	3	100	2	25586182
Pubmed	Upregulation of fibronectin expression by COX-2 is mediated by interaction with ELMO1.	DOCK1 ELMO1	2.45e-05	3	100	2	20732417
Pubmed	Elmo1 helps dock180 to regulate Rac1 activity and cell migration of ovarian cancer.	DOCK1 ELMO1	2.45e-05	3	100	2	24819662
Pubmed	An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling.	DOCK1 ELMO1	2.45e-05	3	100	2	18768751
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	DOCK1 MIER2 LIMA1 CHD7 OSBPL3 RCL1 NHEJ1 CNOT2 CUX1	2.52e-05	536	100	9	15840001
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	MIER2 HSPG2 LIMA1 CCDC174 ACTN4 MIER1 CNOT2	2.56e-05	298	100	7	30737378
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	DOCK1 MIER2 LIMA1 CHD7 OSBPL3 RCL1 NHEJ1 CNOT2 CUX1	2.59e-05	538	100	9	10512203
Pubmed	Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.	PRKCH PLCB3 PLCG2	4.47e-05	24	100	3	10843712
Pubmed	Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.	KDM5C KDM5D	4.89e-05	4	100	2	16541399
Pubmed	Regulation of phospholipase D activity and phosphatidic acid production after purinergic (P2Y6) receptor stimulation.	DGKZ PLD2	4.89e-05	4	100	2	23723068
Pubmed	The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.	KDM5C KDM5D	4.89e-05	4	100	2	17320160
Pubmed	Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.	DOCK1 ELMO1	4.89e-05	4	100	2	14645848
Pubmed	A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.	DOCK1 ELMO1	4.89e-05	4	100	2	15723800
Pubmed	Signaling through the ARK tyrosine kinase receptor protects from apoptosis in the absence of growth stimulation.	AXL MBP	4.89e-05	4	100	2	9395235
Pubmed	CD21 and FCRL5 form a receptor complex with robust B-cell activating capacity.	PLCG2 FCRL5	4.89e-05	4	100	2	30107486
Pubmed	CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.	DOCK1 ELMO1	4.89e-05	4	100	2	11595183
Pubmed	Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation.	DOCK1 PLD2	4.89e-05	4	100	2	23362269
Pubmed	X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.	KDM5C KDM5D	4.89e-05	4	100	2	32732223
Pubmed	A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.	KDM5C KDM5D	4.89e-05	4	100	2	7951230
Pubmed	Association analysis of genes involved in the maintenance of the integrity of the extracellular matrix with intracranial aneurysms in a Japanese cohort.	HSPG2 VCAN	4.89e-05	4	100	2	19506372
Pubmed	Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling.	DGKZ DGKI	4.89e-05	4	100	2	15894621
Pubmed	Characterization of the piRNA complex from rat testes.	LIMA1 RAD54L2 USP2 ARHGAP20 CUX1	5.45e-05	140	100	5	16778019
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	ACTN4 CHD7 MIER1 ELMO1 TRIM66 PIK3CB OSBPL3 VPS13A DHX35 ARHGEF4 MED23 DSCC1 C14orf119	5.76e-05	1242	100	13	30973865
Pubmed	Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.	PRKCH PLCB3 PLCG2	6.42e-05	27	100	3	20336759
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK1 DOCK4 MAX DOCK10 PRC1 ARHGAP11A FAM13B ELMO1 RCL1 ARHGEF4 ARHGAP20	6.69e-05	916	100	11	32203420
Pubmed	Phospholipase C beta3 is a key component in the Gbetagamma/PKCeta/PKD-mediated regulation of trans-Golgi network to plasma membrane transport.	PRKCH PLCB3	8.14e-05	5	100	2	17492941
Pubmed	Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex.	DOCK1 ELMO1	8.14e-05	5	100	2	12134158
Pubmed	Phospholipase D family member 4, a transmembrane glycoprotein with no phospholipase D activity, expression in spleen and early postnatal microglia.	MBP PLD2	8.14e-05	5	100	2	21085684
Pubmed	Identification of a novel protein interaction between Elmo1 and Cdc27.	DOCK1 ELMO1	8.14e-05	5	100	2	26882976
Pubmed	GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180.	DOCK1 ELMO1	8.14e-05	5	100	2	20016009
Pubmed	Differential HDAC1 and 2 Recruitment by Members of the MIER Family.	MIER2 MIER1	8.14e-05	5	100	2	28046085
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	RBM12B CEP192 ACTR1A PIK3CB OSBPL3 YLPM1	8.24e-05	247	100	6	32989298
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	LIMA1 MIA3 DGKZ CHD7 ACTR1A OSBPL3 YLPM1 PAK3 DGKI FRMPD3 CUX1	1.04e-04	963	100	11	28671696
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	PARG PRC1 ARHGAP11A THOC2 MIER1 ACTR1A ALMS1 PPIL2 MED23	1.04e-04	645	100	9	25281560
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	PUS3 KDM5C MAX ZDBF2 CUL5 KMT2C SNX14 CFAP77 PIK3CB YLPM1 PPIL2 CNOT2 HDLBP	1.12e-04	1327	100	13	32694731
Pubmed	Expression and immunohistochemical localization of eight phospholipase C isoforms in adult male mouse cerebellar cortex.	PLCB3 PLCG2	1.22e-04	6	100	2	8739298
Pubmed	The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.	ACTN4 ALMS1	1.22e-04	6	100	2	22693585
Pubmed	The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.	DOCK10 PAK3	1.22e-04	6	100	2	25851601
Pubmed	Differential expression of glycosaminoglycans and proteoglycans in the migratory pathway of the primordial germ cells of the mouse.	HSPG2 VCAN	1.22e-04	6	100	2	12122449
Pubmed	Association between Gαi2 and ELMO1/Dock180 connects chemokine signalling with Rac activation and metastasis.	DOCK1 ELMO1	1.22e-04	6	100	2	23591873
Pubmed	Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets.	PLCB3 PLCG2	1.22e-04	6	100	2	2841328
Pubmed	Over-expression of the chondroitin sulphate proteoglycan versican is associated with defective neural crest migration in the Pax3 mutant mouse (splotch).	HSPG2 VCAN	1.22e-04	6	100	2	9486530
Pubmed	Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models.	PDE6B ALMS1	1.22e-04	6	100	2	37252956
Pubmed	Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.	PTBP3 ACTN4	1.70e-04	7	100	2	11724819
Pubmed	Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin.	HSPG2 VCAN	1.70e-04	7	100	2	37174615
Pubmed	Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.	FCRL5 ARHGAP20	1.70e-04	7	100	2	22044751
Pubmed	A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis.	SLC4A1 VPS13A	1.70e-04	7	100	2	27742708
Pubmed	Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha.	PRKCH PLCB3 PLCG2	1.81e-04	38	100	3	12482669
Pubmed	Bioinformatics and cellular signaling.	DOCK1 ELMO1 MAP3K3 PIK3CB PLCG2	1.87e-04	182	100	5	15102471
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	LIMA1 THOC2 KMT2C ALMS1 YLPM1 MED23 CUX1 HDLBP	1.91e-04	549	100	8	38280479
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	CCDC174 MAX DGKZ MAP3K3 POLR3D RCL1 DHX35 PLD2 RIOK2 C14orf119 CNOT2	2.00e-04	1038	100	11	26673895
Pubmed	JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors.	MAX MAP3K3	2.27e-04	8	100	2	12391307
Pubmed	C-terminal SH3 domain of CrkII regulates the assembly and function of the DOCK180/ELMO Rac-GEF.	DOCK1 ELMO1	2.27e-04	8	100	2	15700267
Pubmed	FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.	FBXL13 CEP192 CCDC198	2.44e-04	42	100	3	29348145
Pubmed	Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy.	NTRK3 MBP PLCG2	2.80e-04	44	100	3	38351062
Pubmed	Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase C nuclear pathway in the Jurkat T cell line.	PLCB3 PLCG2	2.91e-04	9	100	2	7589147
Pubmed	Dual phosphorylation of phosphoinositide 3-kinase adaptor Grb2-associated binder 2 is responsible for superoxide formation synergistically stimulated by Fc gamma and formyl-methionyl-leucyl-phenylalanine receptors in differentiated THP-1 cells.	MBP PIK3CB	2.91e-04	9	100	2	14530346
Pubmed	Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.	PLCB3 PLCG2	2.91e-04	9	100	2	10501179
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DOCK1 CDC42BPG MIA3 MBP CEP192 STK32C CUL5 KMT2C MAST1 PAK3 GREB1 ARHGEF4 CUX1	3.43e-04	1489	100	13	28611215
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MIA3 ACTN4 ZDBF2 CEP192 ALMS1	3.54e-04	209	100	5	36779422
Pubmed	RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo.	DOCK1 ELMO1	3.63e-04	10	100	2	12879077
Pubmed	Expression of phospholipase C isozymes by murine B lymphocytes.	PLCB3 PLCG2	3.63e-04	10	100	2	2033248
Pubmed	Kif14 mutation causes severe brain malformation and hypomyelination.	MBP CUX1	3.63e-04	10	100	2	23308235
Pubmed	Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.	ATP10D ALG14 PLD2	3.63e-04	48	100	3	22359512
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MIER2 MAX CHD7 ARHGAP11A MIER1 RCL1 PPIL2 CUX1	3.79e-04	608	100	8	36089195
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM5C KDM5D KMT2C	3.86e-04	49	100	3	34368113
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	DOCK1 TRAIP THOC2 SCG2 VPS13A PLCG2	3.87e-04	329	100	6	17474147
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	LIMA1 KDM5C PARG CHD7 THOC2 MIER1 YLPM1 PLCB3 HDLBP	4.01e-04	774	100	9	15302935
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	LIMA1 ACTN4 PRC1 THOC2 ACTR1A OSBPL3 PPIL2 DHX35 GFPT2 RIOK2	4.12e-04	949	100	10	36574265
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MIER2 CHD7 MIER1 MYPOP	4.94e-05	53	69	4	532
GeneFamily	PHD finger proteins	KDM5C KDM5D TRIM66 KMT2C	3.88e-04	90	69	4	88
GeneFamily	Phospholipases	PLCB3 PLCG2 PLD2	5.49e-04	42	69	3	467
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKZ DGKI	6.33e-04	10	69	2	1178
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP11A FAM13B ARHGAP20	9.17e-04	50	69	3	721
GeneFamily	X-linked mental retardation\|Angiotensin receptors	KDM5C THOC2 PAK3	1.09e-03	53	69	3	103
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CDC42BPG VEPH1 DOCK10 OSBPL3 ARHGEF4	1.14e-03	206	69	5	682
GeneFamily	AT-rich interaction domain containing	KDM5C KDM5D	1.46e-03	15	69	2	418
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCB3 PLCG2	2.35e-03	19	69	2	832
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5C KDM5D	3.75e-03	24	69	2	485
GeneFamily	Basic helix-loop-helix proteins	MAX ARNT2 ASCL4	8.58e-03	110	69	3	420
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	AXL NTRK3	1.02e-02	40	69	2	321
Coexpression	GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP	DYNC2H1 DGKZ ARHGAP11A ALMS1 GREB1 GFPT2 FRMD5	3.38e-06	165	100	7	M337
Coexpression	ZHENG_BOUND_BY_FOXP3	PTBP3 AXL DOCK10 CHD7 SAMSN1 ELMO1 SNX14 CCDC198 PRKCH CNOT2	2.10e-05	498	100	10	M1741
Coexpression	ZHENG_BOUND_BY_FOXP3	PTBP3 AXL DOCK10 CHD7 SAMSN1 ELMO1 SNX14 CCDC198 PRKCH CNOT2	2.45e-05	507	100	10	MM1030
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRAIP SCG2 ARNT2 DGKI ASCL4 ARHGEF4	2.13e-06	167	100	6	49d9220f22d10ff06c0512c9c40c26ad51728e4f
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRAIP SCG2 ARNT2 DGKI ASCL4 ARHGEF4	2.13e-06	167	100	6	7ec032a98a13504d15c7e3a4e259278d07f40180
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRAIP SCG2 ARNT2 DGKI ASCL4 ARHGEF4	2.13e-06	167	100	6	5e3588eee73693a996bb4846427cf0038ceafbca
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERKL HSPG2 FAT1 VCAN MAST1 GFPT2	3.40e-06	181	100	6	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERKL HSPG2 FAT1 VCAN MAST1 GFPT2	3.40e-06	181	100	6	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 VEPH1 MBP SAMSN1 SLC4A1 PLCG2	4.10e-06	187	100	6	2d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 SLC4A1 OSBPL3 ARNT2 DGKI PLCG2	4.23e-06	188	100	6	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTBP3 LIMA1 PARG MIER1 CUL5 ARHGAP20	4.63e-06	191	100	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTBP3 LIMA1 PARG MIER1 CUL5 ARHGAP20	4.63e-06	191	100	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTBP3 LIMA1 PARG MIER1 CUL5 ARHGAP20	4.63e-06	191	100	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK4 DOCK10 ELMO1 VCAN ARNT2 ARHGAP20	5.06e-06	194	100	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA3 DYNC2H1 KDM5D KMT2C SCG2 VPS13A	5.22e-06	195	100	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA3 DYNC2H1 KDM5D KMT2C SCG2 VPS13A	5.22e-06	195	100	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK10 LRRK1 ELMO1 DGKI PLCG2 FCRL5	5.37e-06	196	100	6	fc67d8aad1ec4d7f98ffe44fb103e230b9b42c35
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NTRK3 ACTN4 FAT1 PAK3 GFPT2 ARHGAP20	5.53e-06	197	100	6	f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRK1 OSBPL3 DGKI PLCG2 FCRL5 HDLBP	5.69e-06	198	100	6	567fcf882c8612356946240843525b786f3c8dbe
ToppCell	(07)_Ionocytes\|World / shred by cell type by condition	LIMA1 BEND5 OSBPL3 ARNT2 DGKI PLCG2	5.86e-06	199	100	6	8194777d367405a7840787e977854b5c07e3bd6b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDC42BPG KDM5C FAT1 ARNT2 DSCC1	2.47e-05	153	100	5	92a5307b8e4dcf9ee42134b4c0645f9d488df61a
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXL13 DGKI PLCG2 FRMPD3 PLD2	2.47e-05	153	100	5	3b1b0cc8e9dd2b1484649789330713282ee44414
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_C-8\|TCGA-Thymus / Sample_Type by Project: Shred V9	POLR3D ARNT2 ASCL4 FCRL5 FRMPD3	2.63e-05	155	100	5	00eef9f93a753a1fe1ab5fd8dae026e7be556cde
ToppCell	normal-na-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	VEPH1 KDM5D PRKCH GREB1 DSCC1	2.63e-05	155	100	5	08295584395e8d9cfc1b1648f98754b3ac53e587
ToppCell	Adult-Immune-B_cell-D122\|Adult / Lineage, Cell type, age group and donor	LRRK1 ABCA7 DGKI PLCG2 FCRL5	2.63e-05	155	100	5	5857aebd43b901fc9f8c46f2d628582969db9e6a
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DOCK4 SCG2 MAST1 DGKI PLCG2	3.55e-05	165	100	5	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	10x5'-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Lung / Manually curated celltypes from each tissue	TRAIP PRC1 ARHGAP11A VCAN GREB1	3.76e-05	167	100	5	82739226347d74897be000f429b73543a031af96
ToppCell	10x5'-Lung-Hematopoietic_progenitors\|Lung / Manually curated celltypes from each tissue	TRAIP PRC1 ARHGAP11A VCAN GREB1	3.76e-05	167	100	5	dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DOCK4 SCG2 MAST1 DGKI PLCG2	3.87e-05	168	100	5	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 LIMA1 SLC4A1 DGKI PLCG2	3.98e-05	169	100	5	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 LIMA1 SLC4A1 DGKI PLCG2	3.98e-05	169	100	5	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 LIMA1 SLC4A1 DGKI PLCG2	3.98e-05	169	100	5	a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HSPG2 AXL NTRK3 DOCK10 PAK3	4.09e-05	170	100	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAIP PRC1 ARHGAP11A OSBPL3 DSCC1	4.32e-05	172	100	5	dd9ba79e1542fe9fa2c319077d83dd3fc0158f46
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MIER2 NTRK3 TRAIP ARHGAP11A ALMS1	4.32e-05	172	100	5	ebeda7ef181cac0109be750a98e7589c615d2724
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 LIMA1 SLC4A1 DGKI PLCG2	4.45e-05	173	100	5	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	facs-Aorta-Heart-3m-Myeloid\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 SAMSN1 ARHGAP11A SLC4A1 PLCG2	4.45e-05	173	100	5	513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAIP ZDBF2 STK32C PRC1 ALMS1	4.45e-05	173	100	5	6c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 DOCK10 SLC4A1 DGKI PLCG2	4.57e-05	174	100	5	5f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LIMA1 DOCK10 SLC4A1 DGKI PLCG2	4.70e-05	175	100	5	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KDM5D ARHGAP11A FCRL5 NHEJ1 TRMT5	4.70e-05	175	100	5	87e557f7508c88b2087db5d57e77d5e2c92ca083
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LIMA1 DOCK10 SLC4A1 DGKI PLCG2	4.70e-05	175	100	5	98947a226b5a2ac7091ff9d34243ea7736add973
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 DOCK10 SLC4A1 DGKI PLCG2	4.82e-05	176	100	5	25ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 LIMA1 SLC4A1 DGKI PLCG2	4.82e-05	176	100	5	cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK4 AXL TRAIP ABCA7 DSCC1	4.82e-05	176	100	5	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 SAMSN1 SLC4A1 DGKI PLCG2	4.96e-05	177	100	5	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	KMT2C ALMS1 ANGEL2 PLD2 MED23	5.09e-05	178	100	5	536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRC1 ARHGAP11A PRKCH DSCC1 FRMD5	5.23e-05	179	100	5	dabecd283c1f0f71a66b804c99be8bd48ea36e35
ToppCell	facs-Kidney-nan-24m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTRK3 SLC4A1 GFPT2 ARHGAP20 DSCC1	5.37e-05	180	100	5	f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCell	COVID-19-Epithelial-Ionocytes\|Epithelial / Condition, Lineage and Cell class	LIMA1 DOCK10 SCG2 DGKI PLCG2	5.51e-05	181	100	5	4a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTBP3 AXL TRAIP PRC1 ARHGAP11A	5.66e-05	182	100	5	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AXL FAT1 VCAN GREB1 GFPT2	5.66e-05	182	100	5	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 MBP DOCK10 CHD7 VCAN	5.96e-05	184	100	5	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC4A1 OSBPL3 ARNT2 DGKI PLCG2	6.27e-05	186	100	5	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 MBP DOCK10 CHD7 VCAN	6.59e-05	188	100	5	60242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BEND5 ZDBF2 SNX14 ARNT2 CNOT2	6.59e-05	188	100	5	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BEND5 ZDBF2 SNX14 ARNT2 CNOT2	6.59e-05	188	100	5	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BEND5 ZDBF2 SNX14 ARNT2 CNOT2	6.59e-05	188	100	5	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 VEPH1 SLC4A1 DGKI PLCG2	6.59e-05	188	100	5	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 MBP DOCK10 CHD7 VCAN	6.59e-05	188	100	5	d9692b6048d9b85524a07a1807bdd4757731c151
ToppCell	COVID-19-Epithelial-Ionocytes\|COVID-19 / Condition, Lineage and Cell class	HSPG2 BEND5 FAT1 SCG2 DGKI	6.59e-05	188	100	5	a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	AXL ZDBF2 FAT1 VCAN GFPT2	6.76e-05	189	100	5	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	HSPG2 ELMO1 VCAN DGKI PRKCH	6.76e-05	189	100	5	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	HSPG2 ELMO1 VCAN DGKI PRKCH	7.28e-05	192	100	5	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK4 HSPG2 ELMO1 PRKCH PLCG2	7.28e-05	192	100	5	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 LIMA1 OSBPL3 ARNT2 PLCG2	7.28e-05	192	100	5	f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 AXL VCAN GFPT2 ARHGAP20	7.28e-05	192	100	5	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMA1 AXL VCAN GFPT2 ARHGAP20	7.28e-05	192	100	5	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 AXL VCAN GFPT2 ARHGAP20	7.28e-05	192	100	5	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 AXL VCAN GFPT2 ARHGAP20	7.28e-05	192	100	5	ac1477433704573f95111eee6263b93668d2845e
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 NTRK3 FAT1 GREB1 FRMPD3	7.28e-05	192	100	5	2cc712186e37fb21a964c032765c36a8b4a852cf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HSPG2 DGKZ ELMO1 PRKCH	7.28e-05	192	100	5	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DOCK4 ELMO1 KMT2C DGKI CUX1	7.46e-05	193	100	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HSPG2 DGKZ ELMO1 PRKCH	7.46e-05	193	100	5	52e918884877b6659cdca0496390e440f73694a9
ToppCell	droplet-Pancreas-Exocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL PRC1 ARHGAP11A VCAN DSCC1	7.65e-05	194	100	5	775600880bb77781de48085d8744c1030223de1f
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	AXL ZDBF2 FAT1 VCAN GFPT2	7.65e-05	194	100	5	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 AXL VCAN GREB1 GFPT2	7.65e-05	194	100	5	ee6b5fb4e993a4c0dc556091b8fefd56bdc70d8f
ToppCell	RA\|World / Chamber and Cluster_Paper	AXL SAMSN1 FAT1 VCAN FRMD5	7.65e-05	194	100	5	08f0afbb68a63150fbe107a5337299081c3f69e4
ToppCell	droplet-Pancreas-Exocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL PRC1 ARHGAP11A VCAN DSCC1	7.65e-05	194	100	5	04ecb609d233a4b12e275c604810937830363e17
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 AXL VCAN GREB1 GFPT2	7.83e-05	195	100	5	841fde528ecb293e07b5e00e499d1e9f0b0dce14
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK4 HSPG2 ELMO1 PRKCH PLCG2	7.83e-05	195	100	5	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	proximal-Hematologic-Natural_Killer_T-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MBP DOCK10 ZDBF2 CEP192 SAMSN1	7.83e-05	195	100	5	4d7c2c4d0130c2d46877ff6dd4584525d8f74daf
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE6B NTRK3 LRRK1 PRC1 FCRL5	7.83e-05	195	100	5	a045fb8a377e54fb57fef1181d4c3fc15d627ef6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 DOCK10 SAMSN1 ELMO1 VCAN	7.83e-05	195	100	5	62dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 LRRK1 SAMSN1 ELMO1 FCRL5	7.83e-05	195	100	5	ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRK1 OSBPL3 DGKI PLCG2 FCRL5	7.83e-05	195	100	5	bb30ac112f8c42d113fa83a9b662e40c0685bb1e
ToppCell	proximal-3-Hematologic-Natural_Killer_T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MBP DOCK10 ZDBF2 CEP192 SAMSN1	7.83e-05	195	100	5	93093545bb23d2619ace029a52cffa1f673a0c2a
ToppCell	proximal-Hematologic-Natural_Killer_T\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MBP DOCK10 ZDBF2 CEP192 SAMSN1	7.83e-05	195	100	5	3944e4800f5d904d4efa401ce8913ec0e0781211
ToppCell	droplet-Heart-nan-18m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VEPH1 MBP SLC4A1 MAST1	7.95e-05	101	100	4	af4a84e4993d4e80c834e1591556b3b3781deaf3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 VEPH1 FAT1 CCDC198 OSBPL3	8.03e-05	196	100	5	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	facs-Trachea\|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 AXL USP2 VCAN GFPT2	8.03e-05	196	100	5	8209f2b0f7efebaaf81d642d18a1aee8a9a8dcf6
ToppCell	facs-Trachea\|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 AXL USP2 VCAN GFPT2	8.03e-05	196	100	5	34020d6553309daa269dff05de0a8567211ea4d2
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRK1 OSBPL3 DGKI PLCG2 FCRL5	8.03e-05	196	100	5	fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 DOCK10 SAMSN1 ELMO1 VCAN	8.22e-05	197	100	5	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK4 AXL DOCK10 SAMSN1 ASCL4	8.22e-05	197	100	5	10190b877bf46ba2163d203df9dd3b498c66e52f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK4 DOCK10 ELMO1 VCAN ARHGAP20	8.22e-05	197	100	5	31a1852911bda38543916585fda34255fd62a134
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZDBF2 KMT2C VPS13A PLCG2 MED23	8.22e-05	197	100	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	severe-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FBXL13 DDI2 KMT2C DGKI PLCG2	8.22e-05	197	100	5	70704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OSBPL3 DGKI PLCG2 FCRL5 HDLBP	8.22e-05	197	100	5	749e0e332644543cbdf2ee38c2b301ce0a019a7f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 SAMSN1 ELMO1 VCAN PRKCH	8.22e-05	197	100	5	c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK10 SAMSN1 OSBPL3 PLCG2 FCRL5	8.42e-05	198	100	5	824461cf44098440ba8bc0df96735423ac65bda1
ToppCell	COVID-19-kidney-Macrophages\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK4 DOCK10 SAMSN1 ELMO1 VCAN	8.42e-05	198	100	5	161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DGKZ CHD7 FAM13B KMT2C PRKCH	8.83e-05	200	100	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
Drug	GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; HL60; HG-U133A	PTBP3 MAX DOCK10 ELMO1 ALMS1 YLPM1 PPIL2 CHPF2 HDLBP	2.28e-07	198	100	9	1625_DN
Drug	AC1L9KC8	HSPG2 DGKZ DGKI PLD2	2.43e-07	13	100	4	CID000446992
Drug	POPC	MBP DGKZ SLC4A1 PIK3CB SCG2 DGKI PRKCH PLCB3 PLCG2 PLD2	9.89e-07	306	100	10	CID000065167
Drug	Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A	DOCK1 LRRK1 ALMS1 RCL1 YLPM1 DHX35 PLCB3 HDLBP	2.57e-06	197	100	8	5815_DN
Drug	diradylglycerol	DGKZ SCG2 DGKI PRKCH PLD2	2.96e-06	51	100	5	CID006437874
Drug	AC1OAGGW	DGKZ ACTR1A PIK3CB DGKI PRKCH PLCB3 PLCG2 PLD2	3.21e-06	203	100	8	CID006857364
Drug	triphosphoinositide	DOCK1 DGKZ ACTR1A PIK3CB DGKI PRKCH PLCB3 PLCG2 PLD2	3.30e-06	273	100	9	CID009543520
Drug	lecithin	MBP DGKZ ABCA7 PIK3CB DGKI PRKCH PLCB3 PLCG2 PLD2	8.08e-06	305	100	9	CID010425705
Drug	AC1Q6T8I	SCG2 PLCB3 PLCG2 PLD2	8.79e-06	30	100	4	CID000000343
Drug	RHC 80267	DGKZ DGKI PRKCH PLCB3 PLCG2 PLD2	1.01e-05	112	100	6	CID000005063
Drug	1,2-diglyceride	DGKZ SCG2 DGKI PRKCH PLCB3 PLCG2 PLD2	1.23e-05	175	100	7	CID000192866
Drug	Scoulerine [6451-73-6]; Up 200; 12.2uM; HL60; HG-U133A	DOCK4 PTBP3 AXL SAMSN1 ATP10D YLPM1 CHPF2	2.03e-05	189	100	7	1742_UP
Drug	phosphatidate	MBP DGKZ SAMSN1 ACTR1A SCG2 DGKI PRKCH PLCB3 PLCG2 PLD2	2.06e-05	432	100	10	CID005460104
Drug	norathyriol	MBP PRKCH PLCB3 PLCG2	2.07e-05	37	100	4	CID005281656
Drug	AC1OAGKW	DGKZ ACTR1A PIK3CB DGKI PLCB3 PLCG2 PLD2	2.32e-05	193	100	7	CID006857413
Drug	Methylprednisolone, 6-alpha [83-43-2]; Down 200; 10.6uM; PC3; HT_HG-U133A	PTBP3 RAD54L2 CUL5 POLR3D PRKCH CHPF2 PLD2	2.40e-05	194	100	7	7137_DN
Drug	wortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A	MIER2 PDE6B TRIM66 SCG2 PPIL2 GREB1 PLD2	2.48e-05	195	100	7	5240_UP
Drug	Trapidil [15421-84-8]; Down 200; 19.4uM; HL60; HT_HG-U133A	PTBP3 BEND5 MAX CUL5 OSBPL3 PPIL2 CHPF2	2.56e-05	196	100	7	3136_DN
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A	HSPG2 CHD7 LRRK1 SCG2 PPIL2 PLCB3 PLCG2	2.56e-05	196	100	7	3762_DN
Drug	Thalidomide [50-35-1]; Down 200; 15.4uM; PC3; HT_HG-U133A	PTBP3 AXL MAX RAD54L2 ALMS1 PRKCH PLCB3	2.65e-05	197	100	7	2095_DN
Drug	Dizocilpine maleate [77086-22-7]; Down 200; 11.8uM; PC3; HT_HG-U133A	KDM5C POLR3D VCAN YLPM1 PPIL2 PLCG2 PLD2	2.65e-05	197	100	7	5746_DN
Drug	Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A	ATP10D USP2 VCAN ANGEL2 VPS13A PRKCH DHX35	2.74e-05	198	100	7	5524_UP
Drug	Tranexamic acid [1197-18-8]; Down 200; 25.4uM; PC3; HT_HG-U133A	DYNC2H1 KDM5C ABCA7 ATP10D POLR3D VPS13A PLCG2	2.74e-05	198	100	7	2085_DN
Drug	Isocorydine (+) [475-67-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TRAIP ANGEL2 YLPM1 PPIL2 CHPF2 ARHGEF4 PLD2	2.74e-05	198	100	7	6843_DN
Drug	Halcinonide [3093-35-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A	MIER2 HSPG2 KDM5C MAX USP2 DHX35 GREB1	2.74e-05	198	100	7	6040_DN
Drug	BAPTA-AM	FAT1 PIK3CB SCG2 PRKCH PLCB3 PLCG2 PLD2 CUX1	4.57e-05	293	100	8	CID000002293
Drug	(2S,3R)-Sphingosine	DGKZ ABCA7 ACTR1A PIK3CB DGKI PRKCH PLCB3 PLCG2 PLD2	5.47e-05	389	100	9	CID000001104
Drug	(S)-1,2-Diolein	MBP DGKZ DGKI PRKCH	6.91e-05	50	100	4	CID000001324
Drug	Cortisporin	DGKZ DGKI PRKCH PLCB3 PLCG2 PLD2	1.32e-04	177	100	6	CID000004454
Drug	AC1NSKHI	DGKZ DGKI PLCB3 PLCG2	1.51e-04	61	100	4	CID005311358
Drug	AC1Q6SH8	SLC4A1 SNX14 PLCB3 PLCG2 PLD2	1.61e-04	116	100	5	CID000000009
Drug	Amoxicillin [26787-78-0]; Down 200; 11uM; MCF7; HT_HG-U133A	PTBP3 MAX RCL1 DHX35 GREB1 PLCG2	1.68e-04	185	100	6	2620_DN
Drug	C8-ceramide	CERKL NTRK3 MBP DGKZ ABCA7 PIK3CB DGKI PRKCH PLD2 CUX1	1.68e-04	556	100	10	CID000002508
Drug	AC1L9HHR	MBP DGKZ ABCA7 SLC4A1 DGKI PRKCH PLCG2 PLD2	1.69e-04	354	100	8	CID000445141
Drug	trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA	MIA3 KDM5C MAX ATP10D SCG2 VPS13A	1.73e-04	186	100	6	1004_UP
Drug	Isotretinoin [4759-48-2]; Down 200; 13.4uM; HL60; HT_HG-U133A	LRRK1 TRIM66 OSBPL3 VCAN VPS13A DHX35	1.73e-04	186	100	6	2407_DN
Drug	fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	PTBP3 KDM5C MAX THOC2 POLR3D PLD2	1.78e-04	187	100	6	1662_UP
Drug	D 609	PRKCH PLCB3 PLCG2 PLD2	1.82e-04	64	100	4	CID000002940
Drug	Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	KDM5C PIK3CB OSBPL3 VPS13A PAK3 PPIL2	1.83e-04	188	100	6	7124_UP
Drug	Digoxigenin [1672-46-4]; Down 200; 10.2uM; HL60; HT_HG-U133A	RBM12B MAX OSBPL3 ANGEL2 VPS13A DSCC1	1.94e-04	190	100	6	3060_DN
Drug	Testosterone propionate [57-85-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A	HSPG2 TRAIP MBP USP2 GREB1 ARHGEF4	2.11e-04	193	100	6	5271_UP
Drug	PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A	MIER2 MIA3 PDE6B KDM5C VCAN VPS13A	2.11e-04	193	100	6	6868_UP
Drug	Carbarsone [121-59-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A	MIER2 NTRK3 MBP DOCK10 RAD54L2 CCDC198	2.17e-04	194	100	6	4110_UP
Drug	Fluphenazine dihydrochloride [146-56-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	TRAIP MAX RAD54L2 GREB1 ARHGEF4 PLD2	2.17e-04	194	100	6	3194_DN
Drug	Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; PC3; HT_HG-U133A	PTBP3 BEND5 DOCK10 SLC4A1 PIK3CB PPIL2	2.17e-04	194	100	6	4015_UP
Drug	NSC618487	AXL MBP DGKZ SLC4A1 ACTR1A PIK3CB PAK3 DGKI PRKCH PLCB3 PLCG2 PLD2 CUX1	2.22e-04	933	100	13	CID000005279
Drug	Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; MCF7; HT_HG-U133A	MAX KDM5D ABCA7 TRIM66 ARHGEF4 PLD2	2.23e-04	195	100	6	3454_UP
Drug	Rimexolone [49697-38-3]; Down 200; 10.8uM; PC3; HT_HG-U133A	MAX LRRK1 POLR3D PIK3CB VCAN CHPF2	2.23e-04	195	100	6	5092_DN
Drug	Tetracycline hydrochloride [64-75-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	DYNC2H1 MAX RAD54L2 GREB1 GFPT2 PLD2	2.23e-04	195	100	6	6233_DN
Drug	Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A	DOCK1 AXL DOCK10 CUL5 PAK3 GFPT2	2.23e-04	195	100	6	7362_DN
Drug	Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; PC3; HT_HG-U133A	PTBP3 ATP10D POLR3D PIK3CB PRKCH ARHGEF4	2.23e-04	195	100	6	7400_DN
Drug	Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A	PTBP3 TRAIP MAX YLPM1 PPIL2 PLD2	2.30e-04	196	100	6	1512_DN
Drug	Homatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A	PTBP3 HSPG2 ACTN4 PIK3CB GREB1 MED23	2.30e-04	196	100	6	1684_UP
Drug	Penbutolol sulfate [38363-32-5]; Down 200; 5.8uM; MCF7; HT_HG-U133A	TRAIP MAX ALMS1 YLPM1 PPIL2 GREB1	2.30e-04	196	100	6	3534_DN
Drug	Ribavirin [36791-04-5]; Up 200; 16.4uM; PC3; HT_HG-U133A	DOCK10 SAMSN1 CCDC198 PIK3CB VCAN PPIL2	2.30e-04	196	100	6	7316_UP
Drug	Ivermectin [70288-86-7]; Down 200; 4.6uM; PC3; HT_HG-U133A	ATP10D CUL5 POLR3D CHPF2 PLCB3 HDLBP	2.30e-04	196	100	6	2051_DN
Drug	staurosporine; Down 200; 0.01uM; SKMEL5; HG-U133A	DOCK10 CEP192 YLPM1 PPIL2 CHPF2 PLD2	2.30e-04	196	100	6	508_DN
Drug	Glycocholic acid [475-31-0]; Up 200; 8.6uM; MCF7; HT_HG-U133A	TRAIP RAD54L2 ALMS1 CHPF2 GREB1 ARHGEF4	2.30e-04	196	100	6	3315_UP
Drug	Rifampicin [13292-46-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A	PDE6B MAX SAMSN1 ALMS1 CHPF2 ARHGEF4	2.30e-04	196	100	6	2847_UP
Drug	Ethamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A	RAD54L2 USP2 ANGEL2 PPIL2 DHX35 GREB1	2.30e-04	196	100	6	7335_UP
Drug	Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A	RAD54L2 ABCA7 ATP10D PPIL2 DHX35 GFPT2	2.36e-04	197	100	6	3934_DN
Drug	Cytisine (-) [485-35-8]; Down 200; 21uM; MCF7; HT_HG-U133A	PTBP3 DYNC2H1 TRAIP RAD54L2 CUL5 GREB1	2.36e-04	197	100	6	6217_DN
Drug	Podophyllotoxin [518-28-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A	TRAIP MAX RAD54L2 ANGEL2 PPIL2 PLD2	2.36e-04	197	100	6	6103_DN
Drug	Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A	PTBP3 TRAIP MAX PPIL2 PLCB3 GREB1	2.36e-04	197	100	6	6105_DN
Drug	Metformin hydrochloride [1115-70-4]; Up 200; 24.2uM; HL60; HT_HG-U133A	DOCK10 ACTN4 CUL5 VCAN VPS13A HDLBP	2.36e-04	197	100	6	1858_UP
Drug	Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A	DOCK1 MAX DHX35 PLCB3 GREB1 PLD2	2.36e-04	197	100	6	5453_DN
Drug	Bisacodyl [603-50-9]; Down 200; 11uM; HL60; HT_HG-U133A	PTBP3 DYNC2H1 TRAIP DOCK10 CHPF2 CUX1	2.36e-04	197	100	6	2435_DN
Drug	Cortisone [53-06-5]; Down 200; 11uM; MCF7; HT_HG-U133A	DOCK1 PTBP3 DYNC2H1 MBP FAM13B PLCG2	2.36e-04	197	100	6	7458_DN
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; PC3; HT_HG-U133A	PTBP3 HSPG2 MIA3 SAMSN1 VCAN PAK3	2.36e-04	197	100	6	4216_DN
Drug	Streptozotocin [18883-66-4]; Down 200; 15uM; HL60; HT_HG-U133A	DYNC2H1 KDM5C ABCA7 CCDC198 GFPT2 ARHGEF4	2.43e-04	198	100	6	2535_DN
Drug	2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A	KDM5C TRAIP ABCA7 ANGEL2 YLPM1 PPIL2	2.43e-04	198	100	6	5582_DN
Drug	Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; PC3; HT_HG-U133A	KDM5C POLR3D VPS13A CHPF2 PLCG2 ARHGEF4	2.43e-04	198	100	6	2054_DN
Drug	Deltaline [6836-11-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A	HSPG2 MAX USP2 SCG2 PPIL2 DHX35	2.43e-04	198	100	6	3831_UP
Drug	Tolnaftate [2398-96-1]; Down 200; 13uM; MCF7; HT_HG-U133A	HSPG2 RAD54L2 YLPM1 PPIL2 DHX35 PLD2	2.43e-04	198	100	6	4805_DN
Drug	arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A	NTRK3 CEP192 YLPM1 PPIL2 CHPF2 GREB1	2.43e-04	198	100	6	441_UP
Drug	Fluphenazine dihydrochloride [146-56-5]; Down 200; 7.8uM; PC3; HT_HG-U133A	TRAIP DOCK10 RAD54L2 ALMS1 PIK3CB VCAN	2.43e-04	198	100	6	5880_DN
Drug	(S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; MCF7; HT_HG-U133A	DOCK1 TRAIP RAD54L2 ATP10D TRIM66 PLD2	2.43e-04	198	100	6	5444_DN
Drug	Solanine alpha [20562-02-1]; Down 200; 4.6uM; PC3; HT_HG-U133A	PDE6B BEND5 AXL ANGEL2 PPIL2 PLD2	2.49e-04	199	100	6	4087_DN
Drug	Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; MCF7; HT_HG-U133A	PTBP3 ARHGAP11A VPS13A PPIL2 PLCB3 GREB1	2.49e-04	199	100	6	3608_DN
Drug	Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A	PUS3 DYNC2H1 KDM5C TRAIP RAD54L2 CUL5	2.49e-04	199	100	6	6219_DN
Drug	Chenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A	DOCK1 MAX YLPM1 PPIL2 PLCB3 GREB1	2.49e-04	199	100	6	7433_DN
Drug	Cefixime [79350-37-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A	DOCK1 PTBP3 KDM5C TRAIP ABCA7 PPIL2	2.49e-04	199	100	6	4390_DN
Drug	Ciprofibrate [52214-84-3]; Down 200; 13.8uM; PC3; HT_HG-U133A	KDM5C LRRK1 POLR3D VCAN PPIL2 PLCB3	2.49e-04	199	100	6	5740_DN
Drug	Lisinopril [83915-83-7]; Down 200; 9uM; MCF7; HT_HG-U133A	MIER2 ARHGAP11A ALMS1 YLPM1 PLCB3 PLD2	2.49e-04	199	100	6	7403_DN
Drug	Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	DOCK4 DYNC2H1 KDM5D ABCA7 OSBPL3 PPIL2	2.49e-04	199	100	6	3169_UP
Drug	aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A_EA	MIER2 PTBP3 TRAIP RAD54L2 PIK3CB PPIL2	2.49e-04	199	100	6	984_DN
Drug	ICI 182,780; Down 200; 1uM; PC3; HT_HG-U133A	PTBP3 TRAIP TRIM66 DHX35 PLCG2 PLD2	2.49e-04	199	100	6	1205_DN
Drug	clofibrate; Up 200; 100uM; MCF7; HG-U133A	NTRK3 CEP192 YLPM1 PPIL2 CHPF2 GREB1	2.49e-04	199	100	6	444_UP
Drug	clozapine; Up 200; 10uM; HL60; HT_HG-U133A	DOCK1 AXL MAX SCG2 PPIL2 PLD2	2.49e-04	199	100	6	6188_UP
Drug	Spironolactone [52-01-7]; Down 200; 9.6uM; PC3; HT_HG-U133A	DOCK1 BEND5 CHD7 PIK3CB VCAN PAK3	2.49e-04	199	100	6	5781_DN
Drug	Meropenem [96036-03-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A	PTBP3 KDM5C RAD54L2 YLPM1 GFPT2 CUX1	2.49e-04	199	100	6	3564_DN
Drug	Acemetacin [53164-05-9]; Down 200; 9.6uM; PC3; HT_HG-U133A	DOCK1 TRAIP ATP10D VCAN PPIL2 ARHGEF4	2.49e-04	199	100	6	6361_DN
Drug	SB 202190; Up 200; 1uM; PC3; HT_HG-U133A	BEND5 ABCA7 CUL5 PPIL2 DHX35 PLCB3	2.49e-04	199	100	6	7058_UP
Drug	Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A	DOCK10 SAMSN1 ABCA7 OSBPL3 PLCB3 ARHGEF4	2.49e-04	199	100	6	5423_UP
Drug	R59949	DGKZ DGKI PRKCH PLD2	2.57e-04	70	100	4	CID000657356
Drug	DIBOA	MAX SLC4A1	2.83e-04	6	100	2	CID000028495
Drug	SKF83742	PLCB3 PLCG2	2.83e-04	6	100	2	CID000130828
Drug	AC1L9K72	MBP DGKZ SCG2 DGKI PLCB3 PLCG2 PLD2	2.95e-04	290	100	7	CID000446872
Drug	C2-ceramide	DGKZ ACTR1A PIK3CB DGKI PRKCH PLD2 CUX1	3.20e-04	294	100	7	CID000002505
Drug	Pkcs	MBP DGKZ PIK3CB PRKCH PLCB3 PLCG2	3.41e-04	211	100	6	CID000164073
Disease	syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)	KDM5C KDM5D	6.52e-05	4	98	2	DOID:0060809 (implicated_via_orthology)
Disease	platelet measurement	MAX DOCK10 ACTN4 ELMO1 RCL1 PLCG2 CUX1	8.92e-05	315	98	7	EFO_0005036
Disease	lactosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement	CHD7 ABCA7	1.08e-04	5	98	2	EFO_0800429
Disease	adenoid cystic carcinoma (is_implicated_in)	NTRK3 KMT2C	1.08e-04	5	98	2	DOID:0080202 (is_implicated_in)
Disease	erythrocyte measurement	CERKL MAX PRC1 ABCA7 SLC4A1 RCL1	2.22e-04	257	98	6	EFO_0005047
Disease	PARTINGTON X-LINKED MENTAL RETARDATION SYNDROME	KDM5C PAK3	3.02e-04	8	98	2	C0796250
Disease	Adenoid Cystic Carcinoma	MIER2 KMT2C FAT1 VCAN	3.51e-04	100	98	4	C0010606
Disease	lymphocyte percentage of leukocytes	CHD7 LRRK1 ABCA7 MIER1 ELMO1 SLC4A1 ULK3 RCL1 PLCB3	3.76e-04	665	98	9	EFO_0007993
Disease	lactosyl-N-nervonoyl-sphingosine (d18:1/24:1) measurement	CHD7 ABCA7	3.87e-04	9	98	2	EFO_0800517
Disease	Malignant neoplasm of salivary gland	MIER2 FAT1 VCAN	4.56e-04	45	98	3	C0220636
Disease	response to carboplatin, response to antineoplastic agent	ULK3 PLCG2	4.83e-04	10	98	2	GO_0097327, GO_0097328
Disease	Salivary Gland Neoplasms	MIER2 FAT1 VCAN	5.18e-04	47	98	3	C0036095
Disease	reticulocyte measurement	MAX ACTN4 SLC4A1 CUL5 FAT1 RCL1 VPS13A MAST1 PLCB3 PLCG2 CUX1	7.48e-04	1053	98	11	EFO_0010700
Disease	renal sinus adipose tissue measurement	FCRL5 ARHGAP20	8.32e-04	13	98	2	EFO_0004864
Disease	schizophrenia (biomarker_via_orthology)	KDM5C MBP	1.11e-03	15	98	2	DOID:5419 (biomarker_via_orthology)
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5C KDM5D	1.27e-03	16	98	2	DOID:0050888 (implicated_via_orthology)
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	NTRK3 TRAIP DOCK10 CHD7 STK32C ELMO1 ALMS1 ASCL4 CUX1	1.40e-03	801	98	9	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	venous thromboembolism, fibrinogen measurement	DGKZ PLCG2 HDLBP	1.46e-03	67	98	3	EFO_0004286, EFO_0004623
Disease	Malignant neoplasm of endometrium	MAX CUX1	1.61e-03	18	98	2	C0007103
Disease	Carcinoma in situ of endometrium	MAX CUX1	1.61e-03	18	98	2	C0346191
Disease	Idiopathic hypogonadotropic hypogonadism	AXL CHD7	1.61e-03	18	98	2	C0342384
Disease	lingual gyrus volume measurement	VEPH1 ASCL4	1.80e-03	19	98	2	EFO_0010314
Disease	mean platelet volume	MAX DOCK10 ACTN4 CHD7 PRC1 ELMO1 BCLAF3 PIK3CB PLCG2 CUX1	2.09e-03	1020	98	10	EFO_0004584
Disease	coronary atherosclerosis measurement, traffic air pollution measurement	DOCK1 SAMSN1	2.20e-03	21	98	2	EFO_0007908, EFO_0007938
Disease	C-reactive protein measurement	DOCK4 TRAIP DGKZ CHD7 CEP192 THOC2 MYPOP ASCL4 PLD2 CUX1 HDLBP	2.21e-03	1206	98	11	EFO_0004458
Disease	venous thromboembolism, tissue plasminogen activator measurement	DGKZ PLCG2	2.64e-03	23	98	2	EFO_0004286, EFO_0004791
Disease	body fat percentage, coronary artery disease	MIA3 DYNC2H1	2.87e-03	24	98	2	EFO_0001645, EFO_0007800
Disease	Malignant neoplasm of breast	DYNC2H1 PRC1 ARHGAP11A CUL5 PIK3CB FCRL5 ARHGEF4 PLD2 CUX1 HDLBP	3.03e-03	1074	98	10	C0006142
Disease	Periodontal Pocket	ELMO1 DHX35	3.12e-03	25	98	2	EFO_1001393

Protein segments in the cluster

Peptide	Gene	Start	Entry
VRDFSPRSRLDFDNQ	BEND5	21	Q7L4P6
ELRRIAFDAESEPNN	ELMO1	326	Q92556
DTFPTEADRQRALKA	CFAP77	286	Q6ZQR2
KEAFQDDPRFLTARD	CUL5	356	Q93034
QDRFREFEDSTLKPN	VCAN	2521	P13611
LDRFIFEDQIRPQDR	SLC4A1	136	P02730
DFERSFQEEKPLERS	ALMS1	2801	Q8TCU4
DQFKSTLPDADRERE	ACTN4	571	O43707
SFVRLRVNQDEPADD	ARHGEF4	246	Q9NR80
INSFELDRADRDPSN	ALG14	81	Q96F25
AFERERLINQFNDPS	RAD54L2	791	Q9Y4B4
VEFFRPDISLLDRDN	ANGEL2	271	Q5VTE6
QAAIDRFSKPDSDRF	CHD7	1346	Q9P2D1
ESPNNDLSRFRGFLE	ATP10D	246	Q9P241
DAFERLGDRQFQSPL	ABCA7	1711	Q8IZY2
EKADAIFSQERDPRF	ARNT2	481	Q9HBZ2
RARDDNPGLRDFEAS	RCL1	36	Q9Y2P8
LEEDFRRSPTEDFRQ	RBM12B	631	Q8IXT5
SRPEEITLRENFDND	RAD21L1	136	Q9H4I0
FRDLLTDEPFSRQDI	PPIL2	141	Q13356
FRDQIRLRFDQPDDF	HSPG2	536	P98160
DEFDIPDLTDNSRRQ	CDC42BPG	1386	Q6DT37
EARDQAREEPQLFST	FAT1	896	Q14517
ELQNPERLSAVFRDF	PAK3	496	O75914
DDNNPFSESFQERER	KMT2C	3386	Q8NEZ4
SDEEQPRFQSAADKR	MAX	11	P61244
FDSEKNESRRNLELP	LIMA1	246	Q9UHB6
LRDEFQTANAREDRP	GREB1	1926	Q4ZG55
DPTLAARKDFQREAE	NTRK3	576	Q16288
RSKFSIADEDARQNP	LRRK1	1676	Q38SD2
RQFEEQFERERNSKP	FAM13B	581	Q9NYF5
ALESEARERRFPNSE	KDM5D	786	Q9BY66
EERLDPFSSFSKRER	CUX1	576	Q13948
DVPLRFRFFRDDQTL	FCRL5	221	Q96RD9
PSRFQARDADIEFRK	PARG	341	Q86W56
EQARSFLDQNPDFAR	PDE6B	6	P35913
DRSLPRAFEIFTDNK	VEPH1	781	Q14D04
FRNRVSDFVKENSPE	MED23	896	Q9ULK4
NLENPDFREIRSFVE	PLCG2	946	P16885
RFSAPQEDEDEARLR	MAST1	806	Q9Y2H9
KFNRSESIRPDEFSL	PLCB3	196	Q01970
DLDIAFFRDIRQTPE	FRMD5	526	Q7Z6J6
LPKEQTRFNRVDEDF	DYNC2H1	1361	Q8NCM8
ETRSSFQKRYPEDRD	BCLAF3	196	A2AJT9
PEDNQERFNSLFSLR	DSCC1	331	Q9BVC3
NVDRDSRFSPLFRQE	DOCK10	571	Q96BY6
RREDFEARLLTQFPN	DOCK1	1366	Q14185
DSKENRPISERFFLR	DOCK4	226	Q8N1I0
LASDFLDRNTPVFRD	GFPT2	401	O94808
SREANPEKFNSRFRN	DGKI	546	O75912
FRDNSSDEDDPKRRA	FRMPD3	706	Q5JV73
FRDFFNQNETSDPAR	DHX35	216	Q9H5Z1
RNEFVRQLEFSEPDF	C14orf119	111	Q9NWQ9
NPRKNRERAAEVFFE	ACTR1A	116	P61163
SFLPFNSSDDVQERR	CERKL	391	Q49MI3
LKRAAAEESNFPERS	FBXL13	126	Q8NEE6
SRDAPGREDNTFKDR	MBP	96	P02686
SDAEPRERLQLSFQD	CEP192	81	Q8TEP8
DSAFEPAFLRKRNER	ASCL4	66	Q6XD76
SKRQSDLRAERDPEF	CCDC174	376	Q6PII3
EQERIRLFSADPFDL	DDI2	186	Q5TDH0
SREANPEKFNSRFRN	DGKZ	466	Q13574
TRTERIPLFDEFFDQ	CCDC198	281	Q9NVL8
FPDNRQEYSDRETQL	MAP3K3	251	Q99759
TARNENDFDEKSERP	MIER1	461	Q8N108
NRSGSRFLADEDREP	MIER2	161	Q8N344
TDTRFRPDQRFLEEG	OSBPL3	806	Q9H4L5
AQRKREDLSPDFSNA	ARHGAP20	981	Q9P2F6
ERDFSPLQTQTFNRE	ARHGAP11A	671	Q6P4F7
DDFLDDPGLRNDTRN	POLR3D	161	P05423
FSKDANPAEDVRQRA	TRMT5	421	Q32P41
DLRSQFPRGRDSEDF	PUS3	131	Q9BZE2
AQRPFERSDFSDSIK	MIA3	821	Q5JRA6
NFDRFRNNSLSKPDD	SAMSN1	26	Q9NSI8
LEFERKASDPNRFTN	PRC1	366	O43663
EENSRDNPFKRTNEI	SCG2	171	P13521
RDRLKTEPFEENSFL	NHEJ1	176	Q9H9Q4
EFDSLKDPEVNEFRR	PIK3CB	136	P42338
TARRPVFDDKEDVNF	STK32C	76	Q86UX6
DSRARLDQSDEDFKP	CHPF2	56	Q9P2E5
DLSDFPALADRNRRE	CNOT2	226	Q9NZN8
RRSDFDFSAPKINLE	VPS13A	266	Q96RL7
RAPKQAESFEDLRRD	THOC2	416	Q8NI27
EFNDRILRPELSNDE	SNX14	371	Q9Y5W7
AFARRPRDDAQISEK	SSX4	6	O60224
QDRPSFTELREDLEN	AXL	791	P30530
FDSDDPLQSVADRLR	ZDBF2	1201	Q9HCK1
NNDKSRDFTRLDLPT	PTBP3	266	O95758
SSLNREFRPFRDEEN	RIOK2	456	Q9BVS4
LDEQESQFRERDIPS	YLPM1	1316	P49750
RDFSVQIKFPDREEN	HDLBP	901	Q00341
RDERASFQERTAAPK	TMC2	101	Q8TDI7
FPLRDLDLREFASEN	USP2	521	O75604
KRFAQPRQEDSDSEE	TRIM66	1151	O15016
QLDRPFEDFIDRETT	PLD2	521	O14939
LERDPSRRISFQDFF	ULK3	251	Q6PHR2
RRPSFRDDIDLNATF	TRAIP	306	Q9BWF2
ALESEARERRFPNSE	KDM5C	796	P41229
FRPRIKSREDVSNFD	PRKCH	631	P24723
ETTRLRKPRFSFEEN	MYPOP	11	Q86VE0