Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A10 SLC4A7 SLC4A8 SLC4A5

3.07e-106444GO:0008510
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A18 SLC4A10 SLC6A11 NDUFA1 ABCA4 SLC4A7 ATP7A SLC4A8 ABCB9 SLC41A3 SLC4A5

4.85e-094774411GO:0022804
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A10 SLC4A7 SLC4A8 SLC4A5

1.44e-0813444GO:0140410
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A18 SLC4A10 SLC6A11 NDUFA1 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

1.59e-08301449GO:0022853
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC4A5

2.30e-0881446GO:0015370
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC41A3 SLC4A5

8.76e-08171447GO:0015081
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A18 SLC4A10 KCNMB2 SLC6A11 TMEM144 NDUFA1 ABCA4 SLC4A7 ATP7A SLC4A8 ABCB9 SLC41A3 SLC4A5 DISP1

1.27e-0711804414GO:0022857
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC4A5

2.32e-07119446GO:0015294
GeneOntologyMolecularFunctiontransporter activity

SLC6A18 SLC4A10 KCNMB2 SLC6A11 TMEM144 NDUFA1 ABCA4 SLC4A7 ATP7A SLC4A8 ABCB9 SLC41A3 SLC4A5 DISP1

3.74e-0712894414GO:0005215
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A18 SLC4A10 KCNMB2 SLC6A11 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

6.41e-07465449GO:0046873
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A10 SLC4A7 SLC4A8 SLC4A5

7.05e-0732444GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A10 SLC4A7 SLC4A8 SLC4A5

7.05e-0732444GO:0005452
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A18 SLC4A10 KCNMB2 SLC6A11 NDUFA1 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

8.21e-076274410GO:0022890
GeneOntologyMolecularFunctionsymporter activity

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC4A5

9.07e-07150446GO:0015293
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC4A5

9.43e-07151446GO:0008509
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A18 SLC4A10 KCNMB2 SLC6A11 NDUFA1 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

1.38e-066644410GO:0008324
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC4A5

1.95e-06171446GO:0015103
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC41A3 SLC4A5

3.51e-06296447GO:0015291
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A18 SLC4A10 KCNMB2 SLC6A11 NDUFA1 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

4.50e-067584410GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A18 SLC4A10 KCNMB2 SLC6A11 NDUFA1 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

6.71e-067934410GO:0015075
GeneOntologyMolecularFunctionantiporter activity

SLC4A10 SLC4A7 SLC4A8 SLC41A3 SLC4A5

1.28e-05138445GO:0015297
GeneOntologyMolecularFunctionsodium,bicarbonate:chloride antiporter activity

SLC4A10 SLC4A8

1.42e-053442GO:0140892
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5D KDM5C

7.08e-056442GO:0034647
GeneOntologyMolecularFunctionG protein-coupled receptor activity

FZD6 CXCR5 GPR141 OR1E3 TAAR2 GPR161 HRH4 OR52R1 GLP2R

1.10e-04884449GO:0004930
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC4A10 SLC4A8 SLC41A3

1.16e-0443443GO:0140828
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5D KDM5C

1.32e-048442GO:0032453
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC6A18 SLC4A10 SLC6A11 SLC4A8

1.64e-04125444GO:0015108
GeneOntologyMolecularFunctionpeptide transmembrane transporter activity

ABCB9 DISP1

1.69e-049442GO:1904680
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC4A10 SLC4A8

3.64e-0413442GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC4A10 SLC4A8

3.64e-0413442GO:0140829
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC4A5

4.47e-04293445GO:0008514
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

FZD6 CXCR5 GPR141 OR1E3 TAAR2 GPR161 HRH4 OR52R1 IL2RA GLP2R

5.85e-0413534410GO:0004888
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

NDUFA1 ABCA4 ATP7A ABCB9

6.27e-04178444GO:0015399
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A18 SLC6A11

6.32e-0417442GO:0015378
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A18 SLC6A11

7.92e-0419442GO:0015373
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A18 SLC6A11

1.17e-0323442GO:0015377
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A18 SLC6A11

1.17e-0323442GO:0005283
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A18 SLC6A11

1.49e-0326442GO:0015296
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM5D KDM5C

1.73e-0328442GO:0141052
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA4 ATP7A ABCB9

1.78e-03109443GO:0042626
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC6A18 SLC6A11

1.86e-0329442GO:0005416
GeneOntologyMolecularFunctionhistone demethylase activity

KDM5D KDM5C

2.12e-0331442GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM5D KDM5C

2.26e-0332442GO:0140457
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

TAAR2 HRH4

3.68e-0341442GO:0008227
GeneOntologyMolecularFunctiondemethylase activity

KDM5D KDM5C

4.23e-0344442GO:0032451
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA4 ABCB9

5.23e-0349442GO:0140359
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM5D KDM5C

9.04e-0365442GO:0016706
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC41A3 SLC4A5

2.27e-07208437GO:0035725
GeneOntologyBiologicalProcessbicarbonate transport

SLC4A10 SLC4A7 SLC4A8 SLC4A5

1.15e-0638434GO:0015701
GeneOntologyBiologicalProcessregulation of intracellular pH

SLC4A10 SLC4A7 SLC4A8 SLC4A5 TM9SF4

1.48e-0694435GO:0051453
GeneOntologyBiologicalProcesssodium ion transport

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC41A3 SLC4A5

1.48e-06275437GO:0006814
GeneOntologyBiologicalProcessregulation of cellular pH

SLC4A10 SLC4A7 SLC4A8 SLC4A5 TM9SF4

2.12e-06101435GO:0030641
GeneOntologyBiologicalProcessregulation of pH

SLC4A10 SLC4A7 SLC4A8 SLC4A5 TM9SF4

4.94e-06120435GO:0006885
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC6A18 SLC4A10 KCNMB2 SLC6A11 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

9.80e-05922439GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC6A18 SLC4A10 KCNMB2 SLC6A11 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

1.15e-04942439GO:0098655
GeneOntologyBiologicalProcessmetal ion transport

SLC6A18 SLC4A10 KCNMB2 SLC6A11 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

1.81e-041000439GO:0030001
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC6A18 SLC4A10 KCNMB2 SLC6A11 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

2.06e-041017439GO:0098660
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC4A10 SLC4A7 SLC4A8 SLC4A5

2.87e-04153434GO:0098656
GeneOntologyBiologicalProcesspyramidal neuron development

SLC4A10 ATP7A

3.26e-0413432GO:0021860
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC6A18 SLC4A10 KCNMB2 SLC6A11 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

4.07e-041115439GO:0034220
GeneOntologyBiologicalProcessinorganic anion transport

SLC4A10 SLC4A7 SLC4A8 SLC4A5

5.31e-04180434GO:0015698
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC6A18 SLC4A10 KCNMB2 SLC6A11 SLC4A7 ATP7A SLC4A8 SLC41A3 SLC4A5

5.33e-041157439GO:0006812
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC4A10 SLC4A7 SLC4A8 SLC4A5

5.65e-04183434GO:0006820
GeneOntologyBiologicalProcesspyramidal neuron differentiation

SLC4A10 ATP7A

7.10e-0419432GO:0021859
GeneOntologyCellularComponentapical plasma membrane

SLC6A18 SLC4A10 FZD6 SLC4A7 ATP7A SLC4A8 SLC4A5

6.48e-05487447GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC6A18 SLC4A10 FZD6 SLC4A7 ATP7A SLC4A8 SLC4A5

2.17e-04592447GO:0045177
GeneOntologyCellularComponentbasolateral plasma membrane

SLC4A10 SLC4A7 ATP7A SLC4A8 SLC4A5

5.42e-04320445GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

SLC4A10 SLC4A7 ATP7A SLC4A8 SLC4A5

8.55e-04354445GO:0009925
GeneOntologyCellularComponentbasal part of cell

SLC4A10 SLC4A7 ATP7A SLC4A8 SLC4A5

1.15e-03378445GO:0045178
MousePhenoabnormal pH regulation

SLC4A10 SLC4A7 ATP7A SLC4A5

3.44e-0642354MP:0004043
MousePhenoabnormal circulating aspartate transaminase level

OR1E3 IL2RA CDKL2 BAZ2B CES2 MARCHF6 EPG5

3.93e-05385357MP:0000203
MousePhenodecreased enzyme/conezyme level

OR1E3 ATP7A IL2RA CDKL2 BAZ2B SLC4A5

6.59e-05284356MP:0014449
MousePhenoabnormal sphingolipid level

NDUFA1 SAMD8 CES2

1.33e-0440353MP:0012230
DomainANION_EXCHANGER_2

SLC4A10 SLC4A7 SLC4A8 SLC4A5

9.33e-107444PS00220
DomainANION_EXCHANGER_1

SLC4A10 SLC4A7 SLC4A8 SLC4A5

9.33e-107444PS00219
DomainBand3_cytoplasmic_dom

SLC4A10 SLC4A7 SLC4A8 SLC4A5

3.35e-099444IPR013769
DomainBand_3_cyto

SLC4A10 SLC4A7 SLC4A8 SLC4A5

3.35e-099444PF07565
Domain-

SLC4A10 SLC4A7 SLC4A8 SLC4A5

3.35e-0994443.40.1100.10
DomainPTrfase/Anion_transptr

SLC4A10 SLC4A7 SLC4A8 SLC4A5

5.57e-0910444IPR016152
DomainHCO3_cotransp

SLC4A10 SLC4A7 SLC4A8 SLC4A5

5.57e-0910444PF00955
DomainHCO3_transpt_euk

SLC4A10 SLC4A7 SLC4A8 SLC4A5

5.57e-0910444IPR003020
DomainHCO3_transpt_C

SLC4A10 SLC4A7 SLC4A8 SLC4A5

5.57e-0910444IPR011531
DomainNa/HCO3_transpt

SLC4A10 SLC4A8 SLC4A5

1.22e-075443IPR003024
DomainLys_sp_deMease-like_dom

KDM5D KDM5C

3.24e-054442IPR013637
DomainPLU-1

KDM5D KDM5C

3.24e-054442PF08429
Domainzf-C5HC2

KDM5D KDM5C

5.40e-055442PF02928
DomainAnion_exchange

SLC4A10 SLC4A7

5.40e-055442IPR001717
DomainZnf_C5HC2

KDM5D KDM5C

5.40e-055442IPR004198
DomainJmjN

KDM5D KDM5C

2.41e-0410442PF02375
DomainJmjN

KDM5D KDM5C

2.41e-0410442SM00545
DomainJMJN

KDM5D KDM5C

2.41e-0410442PS51183
DomainJmjN

KDM5D KDM5C

2.41e-0410442IPR003349
DomainMBOAT_fam

DGAT1 HHATL

2.94e-0411442IPR004299
DomainMBOAT

DGAT1 HHATL

2.94e-0411442PF03062
Domain-

KDM5D KDM5C

5.59e-04154421.10.150.60
DomainARID

KDM5D KDM5C

5.59e-0415442PF01388
DomainBRIGHT

KDM5D KDM5C

5.59e-0415442SM00501
DomainARID_dom

KDM5D KDM5C

5.59e-0415442IPR001606
DomainARID

KDM5D KDM5C

5.59e-0415442PS51011
DomainPHD

KDM5D BAZ2B KDM5C

7.32e-0475443PF00628
DomainNA_NEUROTRAN_SYMP_2

SLC6A18 SLC6A11

8.10e-0418442PS00754
DomainZnf_PHD-finger

KDM5D BAZ2B KDM5C

8.51e-0479443IPR019787
DomainNA_NEUROTRAN_SYMP_3

SLC6A18 SLC6A11

9.04e-0419442PS50267
DomainSNF

SLC6A18 SLC6A11

9.04e-0419442PF00209
DomainNa/ntran_symport

SLC6A18 SLC6A11

9.04e-0419442IPR000175
DomainNA_NEUROTRAN_SYMP_1

SLC6A18 SLC6A11

9.04e-0419442PS00610
DomainPHD

KDM5D BAZ2B KDM5C

1.20e-0389443SM00249
DomainZnf_PHD

KDM5D BAZ2B KDM5C

1.28e-0391443IPR001965
DomainJmjC

KDM5D KDM5C

1.45e-0324442PF02373
DomainZF_PHD_2

KDM5D BAZ2B KDM5C

1.45e-0395443PS50016
DomainZF_PHD_1

KDM5D BAZ2B KDM5C

1.50e-0396443PS01359
DomainJMJC

KDM5D KDM5C

2.57e-0332442PS51184
DomainJmjC_dom

KDM5D KDM5C

2.57e-0332442IPR003347
DomainJmjC

KDM5D KDM5C

2.73e-0333442SM00558
DomainABC_transporter_CS

ABCA4 ABCB9

4.40e-0342442IPR017871
DomainGPCR_Rhodpsn_7TM

CXCR5 GPR141 TAAR2 GPR161 HRH4 OR52R1

4.61e-03670446IPR017452
DomainAAA+_ATPase

DNAH3 ABCA4 ABCB9

4.72e-03144443IPR003593
DomainAAA

DNAH3 ABCA4 ABCB9

4.72e-03144443SM00382
Domain7tm_1

CXCR5 GPR141 TAAR2 GPR161 HRH4 OR52R1

4.84e-03677446PF00001
DomainZnf_FYVE_PHD

KDM5D BAZ2B KDM5C

5.00e-03147443IPR011011
DomainG_PROTEIN_RECEP_F1_1

CXCR5 GPR141 TAAR2 GPR161 HRH4 OR52R1

5.13e-03685446PS00237
DomainG_PROTEIN_RECEP_F1_2

CXCR5 GPR141 TAAR2 GPR161 HRH4 OR52R1

5.35e-03691446PS50262
DomainGPCR_Rhodpsn

CXCR5 GPR141 TAAR2 GPR161 HRH4 OR52R1

5.38e-03692446IPR000276
DomainABC_TRANSPORTER_2

ABCA4 ABCB9

5.71e-0348442PS50893
DomainABC_tran

ABCA4 ABCB9

5.71e-0348442PF00005
DomainABC_TRANSPORTER_1

ABCA4 ABCB9

5.95e-0349442PS00211
DomainABC_transporter-like

ABCA4 ABCB9

6.18e-0350442IPR003439
DomainGPCR_2-like

FZD6 GLP2R

8.80e-0360442IPR017981
DomainGPCR_2_secretin-like

FZD6 GLP2R

8.80e-0360442IPR000832
DomainG_PROTEIN_RECEP_F2_4

FZD6 GLP2R

9.09e-0361442PS50261
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A10 SLC4A7 SLC4A8 SLC4A5

6.61e-0910354M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A10 SLC4A7 SLC4A8 SLC4A5

6.61e-0910354MM15073
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A18 SLC4A10 SLC4A7 SLC4A8 SLC4A5

6.50e-06108355M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A18 SLC4A10 SLC4A7 SLC4A8 SLC4A5

6.80e-06109355MM15074
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC4A5

2.34e-05238356MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC4A5

3.02e-05249356M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A18 SLC4A10 SLC6A11 ABCA4 SLC4A7 ATP7A SLC4A8 ABCB9 SLC4A5

3.09e-05681359MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A18 SLC4A10 SLC6A11 ABCA4 SLC4A7 ATP7A SLC4A8 ABCB9 SLC4A5

5.68e-05736359M27287
PathwayWP_GPCRS_ODORANT

GPR141 OR1E3 TAAR2 GPR161

5.92e-04157354MM15872
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A18 SLC6A11

9.97e-0419352MM15107
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A18 SLC6A11

9.97e-0419352M27362
Pubmed

Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissues.

SLC4A7 SLC4A8 SLC4A5

8.65e-09446317715183
Pubmed

Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.

SLC4A10 SLC4A7 SLC4A8

2.16e-08546323500099
Pubmed

Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene).

SLC4A10 SLC4A7 SLC4A5

4.72e-071246321705333
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5D KDM5C

1.71e-06246232081420
Pubmed

K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.

SLC4A10 SLC4A8

1.71e-06246238674160
Pubmed

Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.

SLC4A10 SLC4A7

1.71e-06246217928512
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5D KDM5C

1.71e-0624629060413
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5D KDM5C

1.71e-06246210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5D KDM5C

1.71e-06246216416087
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5D KDM5C

1.71e-0624627524912
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

GPR141 TAAR2 GPR161 GLP2R

3.74e-067946412679517
Pubmed

The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.

SLC4A7 SLC4A8

5.13e-06346212444018
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5D KDM5C

5.13e-0634627544442
Pubmed

Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA.

SLC4A7 SLC4A8

5.13e-06346214736710
Pubmed

Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.

KDM5D KDM5C

1.03e-05446216541399
Pubmed

The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3.

SLC4A7 SLC4A8

1.03e-05446212403779
Pubmed

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

KDM5D KDM5C

1.03e-05446232732223
Pubmed

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

KDM5D KDM5C

1.03e-0544627951230
Pubmed

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

KDM5D KDM5C

1.03e-05446217320160
Pubmed

A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.

SLC4A10 SLC4A7

1.03e-05446214592810
Pubmed

Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice.

SLC4A10 SLC4A7

2.56e-05646231001720
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

NDUFA1 ABCA4 ABCB9 CES2

1.25e-0419346419343046
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KDM5D KDM5C

1.32e-041346224619213
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

KDM5D KDM5C

1.32e-041346214660691
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

KDM5D KDM5C

1.78e-041546214762062
Pubmed

Role of TNF ligand and receptor family in the lymphoid organogenesis defined by gene targeting.

CXCR5 IL2RA

2.03e-041646210687308
Pubmed

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.

ATP7A KDM5C

2.30e-041746219571810
Pubmed

Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass.

ATP7A KDM5C

2.30e-041746221471155
Pubmed

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.

CXCR5 ABCA4 SLC4A7 EPG5

2.57e-0423346432290105
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

KDM5D KDM5C

2.58e-041846212023983
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

GPR161 TMEM144 SLC41A3 DGAT1 HHATL MARCHF6

3.00e-0469746628298427
Pubmed

The repertoire of solute carriers of family 6: identification of new human and rodent genes.

SLC6A18 SLC6A11

3.54e-042146216125675
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCA4 ABCB9

3.89e-04224628894702
Pubmed

Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation.

ATP7A KDM5C

4.25e-042346222573614
Pubmed

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

CXCR5 TEC IL2RA

4.46e-0411246324390342
Pubmed

Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.

ABCA4 EPG5

5.88e-042746218649358
Pubmed

Integral and associated lysosomal membrane proteins.

HGSNAT ABCB9 PGAP6

6.29e-0412646317897319
Pubmed

DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease.

CXCR5 IL2RA

8.80e-043346227760760
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM5D KDM5C

8.80e-043346226864203
Pubmed

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

CXCR5 TEC IL2RA TM9SF4

1.08e-0334246423128233
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

KDM5D BAZ2B KDM5C

1.19e-0315746330186101
InteractionC15orf32 interactions

DPY19L4 HGSNAT DISP1

2.37e-0613423int:C15orf32
InteractionSLC17A2 interactions

DPY19L4 ABCB9 SLC41A3 MARCHF6

5.53e-0656424int:SLC17A2
InteractionATP2B2 interactions

GPR161 SLC4A7 ABCB9 IL2RA DGAT1

5.51e-05198425int:ATP2B2
InteractionVNN2 interactions

DPY19L4 FZD6 TM9SF4

1.45e-0449423int:VNN2
Cytoband2q24.2

SLC4A10 BAZ2B

2.24e-04224622q24.2
GeneFamilySolute carriers

SLC6A18 SLC4A10 SLC6A11 SLC4A7 SLC4A8 SLC41A3 SLC4A5

8.93e-06395357752
GeneFamilyAT-rich interaction domain containing

KDM5D KDM5C

3.76e-0415352418
GeneFamilyPHD finger proteins

KDM5D BAZ2B KDM5C

6.96e-049035388
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5D KDM5C

9.78e-0424352485
GeneFamilyG protein-coupled receptors, Class A orphans

GPR141 GPR161

9.97e-0378352262
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCNMB2 DNAH3 SLC4A8 KDM5D

1.85e-05156454a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HRH4 TEC SLC41A3 DGAT1

2.72e-05172454c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCelldroplet-Lung-nan-21m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRH4 SLC41A3 TEC DGAT1

2.72e-05172454b3c53fd7e50f36de6a8585ae21d04e17932f262c
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HRH4 TEC SLC41A3 DGAT1

2.72e-05172454953b05f776348cff784e79c93df65841939d880f
ToppCelldroplet-Lung-nan-21m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRH4 SLC41A3 TEC DGAT1

2.72e-051724541b133be191252e7053faeacf9547730c3ae28d21
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HRH4 SLC41A3 TEC DGAT1

2.84e-051744548a8e98e62c2859c004b44dbce6974c9639ebeac6
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HRH4 SLC41A3 TEC DGAT1

2.84e-0517445431f7127faabcb1092bb9827db625f57cf7d8240e
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRH4 SLC41A3 TEC DISP1

3.11e-05178454cc0382b0ee1e6c76522e2c86ad1425c45debab5d
Diseaseanemia (implicated_via_orthology)

SLC4A10 SLC4A7 SLC4A8 SLC4A5

6.36e-0915454DOID:2355 (implicated_via_orthology)
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5D KDM5C

1.36e-054452DOID:0060809 (implicated_via_orthology)
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

1.36e-054452EFO_0020830
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5D KDM5C

2.69e-0416452DOID:0050888 (implicated_via_orthology)
Diseasethyroxine measurement, triiodothyronine measurement

CCDC80 ABCB9

3.05e-0417452EFO_0005130, EFO_0008392
Diseasecystathionine measurement

TEC TEC

3.83e-0419452EFO_0010474
Diseasemyositis

TEC TEC

1.63e-0339452EFO_0000783
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

TEC IL2RA TEC

2.23e-03170453EFO_0000685, EFO_0007791, EFO_0007837
Diseaseglucose-dependent insulinotropic peptide measurement

ABCB9 SLC41A3

2.98e-0353452EFO_0008464

Protein segments in the cluster

PeptideGeneStartEntry
LGIWLFMSEMPFGTL

EPG5

701

Q9HCE0
GFLLPMLVMGWCYVG

CXCR5

226

P32302
MPSAGMLPWLQGIFC

ABCA4

61

P78363
VSMMGLQFCGWPTGV

BAZ2B

1626

Q9UIF8
FTGMMAQIPLAWFVG

DGAT1

431

O75907
ADWPVVVLGMCTMFI

DISP1

186

Q96F81
GPRFTMLLAMWLVCG

CCDC80

6

Q76M96
VFMPIGLVLQPWMGS

ATP7A

1376

Q04656
WMFGLPFCKFVSAML

GPR141

81

Q7Z602
LIGFAGAPWTLMTYM

UROD

151

P06132
FWPTCMMAGGVAIVA

KCNMB2

201

Q9Y691
GALAVMGTMGPWYLL

HHATL

106

Q9HCP6
GGMIAWLIAICYPEM

EPHX4

171

Q8IUS5
GMKVPWLYVGMVFSA

KDM5D

486

Q9BY66
PVMVWIHGGALVFGM

CES2

141

O00748
APGTTMFLHWLVGMV

MARCHF6

416

O60337
WNMLGPCLFAFVIMA

PGAP6

656

Q9HCN3
VMLRGLLWVSPFCFM

OR52R1

151

Q8NGF1
WAIGCLVTEMFMGEP

CDKL2

186

Q92772
AWGTPGFLTVMLLAM

FZD6

331

O60353
WIIRGPMMLCVTVNF

GLP2R

341

O95838
MFMWLVQPCLEFGRL

DNAH3

1886

Q8TD57
MLAAFGVCSPELWMT

DPY19L4

496

Q7Z388
LMWGLLTFIMVPGCQ

IL2RA

6

P01589
LGAFMVTWGPYMVVI

GPR161

276

Q8N6U8
PWFVFIMGSSIFLSM

HGSNAT

311

Q68CP4
MWFEILPGLSVMGVC

NDUFA1

1

O15239
GWVMFFMGGLILVIP

OR1E3

196

Q8WZA6
MVAVWVLAFLVNGPM

HRH4

136

Q9H3N8
MLGVCSVMGLPWFVA

SLC4A7

961

Q9Y6M7
RIPWAFAMTEVCGMI

SAMD8

196

Q96LT4
FGVLMWEVFTEGRMP

TEC

551

P42680
VPFMFAGLGLSWAGM

SLC41A3

71

Q96GZ6
MLGVCSIMGLPWFVA

SLC4A8

831

Q2Y0W8
LPFFFVLGGTMEWIM

SMIM4

26

Q8WVI0
MPGAPVWAMLFFGML

SLC6A18

396

Q96N87
WQLSLVTFMGFPIIM

ABCB9

326

Q9NP78
FPTMVALLCMWFGIS

TM9SF4

446

Q92544
GPGFIAAMWGIFMFK

TMEM144

301

Q7Z5S9
EGFLFKEMMTWVQGP

WDR97

1321

A6NE52
VMLGVCSIMGLPWFV

SLC4A10

861

Q6U841
WMIMTPGICAGIFIF

SLC6A11

516

P48066
WVGILMALCSFMGLP

SLC4A5

876

Q9BY07
CPVMFNKLWGTTLFM

TAAR2

201

Q9P1P5
MGFLMVCLGAFFISW

TMEM252

16

Q8N6L7
GMKVPWLYVGMVFSA

KDM5C

496

P41229