Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentsperm end piece

FSIP2 AKAP4

7.76e-0531072GO:0097229
GeneOntologyCellularComponentsperm head-tail coupling apparatus

CFAP47 FSIP2 AKAP4

1.01e-04181073GO:0120212
DomainZINC_FINGER_C2H2_1

ZHX3 ZNF705A ZNF138 ZNF695 ZNF155 TUT7 APTX ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN10 ZSCAN20 ZNF655 ZNF644 ZNF679

5.97e-0677710416PS00028
DomainZnf_C2H2

ZHX3 ZNF705A ZNF138 ZNF695 ZNF155 TUT7 APTX ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN10 ZSCAN20 ZNF655 ZNF644 ZNF679

9.32e-0680510416IPR007087
DomainZINC_FINGER_C2H2_2

ZHX3 ZNF705A ZNF138 ZNF695 ZNF155 APTX ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN10 ZSCAN20 ZNF655 ZNF644 ZNF679

2.49e-0577510415PS50157
DomainZnf_C2H2-like

ZHX3 ZNF705A ZNF138 ZNF695 ZNF155 APTX ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN10 ZSCAN20 ZNF655 ZNF644 ZNF679

3.39e-0579610415IPR015880
DomainZnF_C2H2

ZHX3 ZNF705A ZNF138 ZNF695 ZNF155 APTX ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN10 ZSCAN20 ZNF655 ZNF644 ZNF679

4.02e-0580810415SM00355
Domain-

ZNF705A ZNF138 ZNF695 ZNF155 ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN10 ZSCAN20 ZNF655 ZNF644 ZNF679

1.01e-04679104133.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF705A ZNF138 ZNF695 ZNF155 ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN10 ZSCAN20 ZNF655 ZNF644 ZNF679

1.25e-0469410413IPR013087
DomainAnk_2

TEX14 IBTK ANKRD34B OSBPL1A ANKRD11 ANKRD30A ANKRD12

2.01e-042151047PF12796
DomainKRAB

ZNF705A ZNF695 ZNF155 ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN20 ZNF679

2.19e-043691049SM00349
DomainKRAB

ZNF705A ZNF695 ZNF155 ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN20 ZNF679

2.24e-043701049IPR001909
DomainAnk

TEX14 IBTK ANKRD34B OSBPL1A ANKRD11 ANKRD30A ANKRD12

2.87e-042281047PF00023
Domainzf-C2H2

ZNF705A ZNF138 ZNF695 ZNF155 ZNF101 ZNF235 ZNF514 ZSCAN10 ZSCAN20 ZNF655 ZNF644 ZNF679

4.72e-0469310412PF00096
Domain-

TEX14 IBTK ANKRD34B OSBPL1A ANKRD11 ANKRD30A ANKRD12

4.76e-0424810471.25.40.20
DomainANK

TEX14 IBTK ANKRD34B OSBPL1A ANKRD11 ANKRD30A ANKRD12

5.11e-042511047SM00248
DomainANK_REPEAT

TEX14 IBTK ANKRD34B OSBPL1A ANKRD11 ANKRD30A ANKRD12

5.36e-042531047PS50088
DomainAnkyrin_rpt-contain_dom

TEX14 IBTK ANKRD34B OSBPL1A ANKRD11 ANKRD30A ANKRD12

5.49e-042541047IPR020683
DomainANK_REP_REGION

TEX14 IBTK ANKRD34B OSBPL1A ANKRD11 ANKRD30A ANKRD12

5.49e-042541047PS50297
DomainAnkyrin_rpt

TEX14 IBTK ANKRD34B OSBPL1A ANKRD11 ANKRD30A ANKRD12

6.59e-042621047IPR002110
DomainKRAB

ZNF705A ZNF695 ZNF155 ZNF101 ZNF235 ZNF705G ZNF514 ZNF679

8.78e-043581048PS50805
DomainKRAB

ZNF705A ZNF695 ZNF155 ZNF101 ZNF235 ZNF705G ZNF514 ZNF679

8.78e-043581048PF01352
DomainZnf_FYVE_PHD

ATRX ZFYVE16 MTF2 PHRF1 FGD6

1.39e-031471045IPR011011
DomainOxysterol-bd

OSBP OSBPL1A

1.95e-03121042IPR000648
DomainOxysterol-bd_CS

OSBP OSBPL1A

1.95e-03121042IPR018494
DomainOxysterol_BP

OSBP OSBPL1A

1.95e-03121042PF01237
DomainOSBP

OSBP OSBPL1A

1.95e-03121042PS01013
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH11

2.68e-03141042IPR024317
DomainDynein_HC_stalk

DNAH14 DNAH11

2.68e-03141042IPR024743
DomainMT

DNAH14 DNAH11

2.68e-03141042PF12777
DomainAAA_8

DNAH14 DNAH11

2.68e-03141042PF12780
DomainSANT

BDP1 GON4L ZSCAN20

2.72e-03501043SM00717
DomainSANT/Myb

BDP1 GON4L ZSCAN20

3.04e-03521043IPR001005
DomainDHC_fam

DNAH14 DNAH11

3.08e-03151042IPR026983
DomainDynein_heavy_dom

DNAH14 DNAH11

3.08e-03151042IPR004273
DomainDynein_heavy

DNAH14 DNAH11

3.08e-03151042PF03028
DomainPH

DGKH OSBP ELMO3 PLEKHM2 OSBPL1A FGD6

4.63e-032781046SM00233
DomainPH_DOMAIN

DGKH OSBP ELMO3 PLEKHM2 OSBPL1A FGD6

4.71e-032791046PS50003
DomainPH_domain

DGKH OSBP ELMO3 PLEKHM2 OSBPL1A FGD6

4.79e-032801046IPR001849
DomainDSRM

NKRF TARBP2

4.94e-03191042SM00358
Domaindsrm

NKRF TARBP2

5.47e-03201042PF00035
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

ATRX REV3L NKRF MLH3 NOP14 BRD2 BRCA1 ZNF644 POLK

4.30e-08222111937071664
Pubmed

A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

USP34 ATR BRCA1

3.74e-0610111317478428
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

USP34 ATRX MAP4 TUT7 KBTBD8 ZNF101 ZSCAN10 ZNF655 IRAK4 TMEM131 ANKRD12 POLK GEN1 FAM135A

9.52e-0610841111411544199
Pubmed

An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication.

ATR BRCA1

1.01e-052111216738325
Pubmed

Knockdown of REV3 synergizes with ATR inhibition to promote apoptosis induced by cisplatin in lung cancer cells.

ATR REV3L

1.01e-052111228075014
Pubmed

ATRX proximal protein associations boast roles beyond histone deposition.

ATRX CENPC NOP14 ZNF655 ZNF644

1.13e-0591111534780483
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BDP1 USP34 ATRX CENPE ZNF644 DDX20 CRYBG3 SIPA1L2 POLK FAM135A

1.98e-055881111038580884
Pubmed

ATR/ATM-Mediated Phosphorylation of BRCA1 T1394 Promotes Homologous Recombinational Repair and G2-M Checkpoint Maintenance.

ATR BRCA1

3.02e-053111234301763
Pubmed

Development of serous ovarian cancer is associated with the expression of homologous recombination pathway proteins.

ATR BRCA1

3.02e-053111224752797
Pubmed

Nedd8-activating enzyme inhibitor MLN4924 provides synergy with mitomycin C through interactions with ATR, BRCA1/BRCA2, and chromatin dynamics pathways.

ATR BRCA1

3.02e-053111224672057
Pubmed

Translesion synthesis of 6-nitrochrysene-derived 2'-deoxyadenosine adduct in human cells.

REV3L POLK

3.02e-053111232721818
Pubmed

A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.

ATR BRCA1

3.02e-053111212773400
Pubmed

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.

ATR BRCA1

3.02e-053111211114888
Pubmed

BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation.

ATR BRCA1

3.02e-053111215589157
Pubmed

Homozygous loss-of-function mutations in FSIP2 cause male infertility with asthenoteratospermia.

FSIP2 AKAP4

3.02e-053111230745215
Pubmed

Whole-exome sequencing identifies mutations in FSIP2 as a recurrent cause of multiple morphological abnormalities of the sperm flagella.

FSIP2 AKAP4

3.02e-053111230137358
Pubmed

Coupling of Homologous Recombination and the Checkpoint by ATR.

ATR BRCA1

3.02e-053111228089683
Pubmed

Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies.

ATR BRCA1

3.02e-053111211278964
Pubmed

ATR, BRCA1 and gammaH2AX localize to unsynapsed chromosomes at the pachytene stage in human oocytes.

ATR BRCA1

3.02e-053111219146767
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYH11 ATR MAP4 TUT7 ANKRD30A NEURL4

4.86e-05202111633005030
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZHX3 ZFYVE16 GON4L NEDD4 PLEKHM2 ZNF644 ANKRD12 SIPA1L2

5.08e-05407111812693553
Pubmed

ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes.

ATRX CENPC

6.03e-054111215242786
Pubmed

Interaction between BRCA1/BRCA2 and ATM/ATR associate with breast cancer susceptibility in a Chinese Han population.

ATR BRCA1

6.03e-054111220513533
Pubmed

ATR and GADD45alpha mediate HIV-1 Vpr-induced apoptosis.

ATR BRCA1

6.03e-054111215650754
Pubmed

Phosphorylation of ATR-interacting protein on Ser239 mediates an interaction with breast-ovarian cancer susceptibility 1 and checkpoint function.

ATR BRCA1

6.03e-054111217616665
Pubmed

Ataxia telangiectasia-related protein is involved in the phosphorylation of BRCA1 following deoxyribonucleic acid damage.

ATR BRCA1

6.03e-054111211016625
Pubmed

Molecular phenotyping and functional assessment of smooth muscle-like cells with pathogenic variants in aneurysm genes ACTA2, MYH11, SMAD3 and FBN1.

MYH11 FBN1

6.03e-054111234244757
Pubmed

Function of the ATR N-terminal domain revealed by an ATM/ATR chimera.

ATR BRCA1

6.03e-054111217376433
Pubmed

Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ.

REV3L POLK

6.03e-054111222859295
Pubmed

ATR inhibition broadly sensitizes ovarian cancer cells to chemotherapy independent of BRCA status.

ATR BRCA1

6.03e-054111223548269
Pubmed

A novel human rad54 homologue, Rad54B, associates with Rad51.

ATRX BRCA1

6.03e-054111210851248
Pubmed

LncRNA Sox2ot modulates the progression of thoracic aortic aneurysm by regulating miR-330-5p/Myh11.

MYH11 FBN1

6.03e-054111232578852
Pubmed

Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.

ATR MLH3 BRCA1 POLK

6.84e-0568111420496165
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ATRX CENPC LIFR NOP14 R3HCC1L BRD2 ZNF644 ANKRD11 TMEM131 MRPL3 CRYBG3 SIPA1L2 FAM135A NEURL4 TARBP2

7.82e-0514871111533957083
Pubmed

Promoter methylation patterns of ATM, ATR, BRCA1, BRCA2 and p53 as putative cancer risk modifiers in Jewish BRCA1/BRCA2 mutation carriers.

ATR BRCA1

1.00e-045111218642075
Pubmed

Inactivation of the Nijmegen breakage syndrome gene leads to excess centrosome duplication via the ATR/BRCA1 pathway.

ATR BRCA1

1.00e-045111219244116
Pubmed

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.

ATR BRCA1

1.00e-045111215159397
Pubmed

A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.

FSIP2 AKAP4

1.00e-045111212606363
Pubmed

Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.

ATR BRCA1

1.00e-045111215485898
Pubmed

Mammalian centromeres: DNA sequence, protein composition, and role in cell cycle progression.

CENPC CENPE

1.00e-04511129925740
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZHX3 ATRX CENPC MTF2 FSIP2 NOP14 BRD2 BRCA1 ZNF644

1.49e-04608111936089195
Pubmed

BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.

ATRX BRCA1

1.50e-046111228976962
Pubmed

Family of human oxysterol binding protein (OSBP) homologues. A novel member implicated in brain sterol metabolism.

OSBP OSBPL1A

1.50e-046111210588946
Pubmed

Human SNF5/INI1, a component of the human SWI/SNF chromatin remodeling complex, promotes nucleotide excision repair by influencing ATM recruitment and downstream H2AX phosphorylation.

ATR BRCA1

1.50e-046111219805520
Pubmed

GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability.

ATR BRCA1

1.50e-046111231839538
Pubmed

Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest.

ATR ATRX

1.50e-046111217118963
Pubmed

Interaction of hREV1 with three human Y-family DNA polymerases.

REV3L POLK

1.50e-046111215189446
Pubmed

Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.

REV3L MLH3 BRCA1 POLK

1.56e-0484111419237606
Pubmed

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A.

CENPC CENPE

2.10e-047111211682612
Pubmed

Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells.

MYH11 FBN1

2.10e-047111221778429
Pubmed

Ethanol-induced intracellular calcium mobilization rapidly alters gene expression in the mouse blastocyst.

ZNF101 FGD6

2.10e-04711129502196
Pubmed

Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.

ATR BRCA1

2.10e-047111222549958
Pubmed

Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7.

ZNF155 ZNF235

2.10e-04711128617494
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

ATRX HPSE2 CCDC168 FSIP2 ANKRD11

2.10e-04168111530631154
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZHX3 MTF2 TUT7 ZNF235 IBTK ZSCAN20 BRD2 ZNF655 ZNF644 ZNF679

2.71e-048081111020412781
Pubmed

SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.

ATR BRCA1

2.79e-048111230393076
Pubmed

Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.

ATR BRCA1

2.79e-048111215456891
Pubmed

HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.

ATR BRCA1

2.79e-048111223039116
Pubmed

HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT.

ATR BRCA1

2.79e-048111217140287
Pubmed

Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes.

DDX20 TARBP2

2.79e-048111220211803
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ATRX MAP4 APTX PHRF1 GON4L SRFBP1 NKRF NOP14 BRD2 BRCA1 TBC1D10A ANKRD11 DDX20 TARBP2

3.00e-0414971111431527615
Pubmed

Urinary tract effects of HPSE2 mutations.

MYH11 HPSE2

3.58e-049111225145936
Pubmed

BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes.

ATR BRCA1

3.58e-049111219531582
Pubmed

Identification of a novel family of ankyrin repeats containing cofactors for p160 nuclear receptor coactivators.

ANKRD11 ANKRD12

3.58e-049111215184363
Pubmed

HIV-1 accessory proteins: VpR.

ATR BRCA1

3.58e-049111224158819
Pubmed

BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade.

ATR BRCA1

3.58e-049111223901102
Pubmed

Vpr-induced DNA double-strand breaks: molecular mechanism and biological relevance.

ATR BRCA1

3.58e-049111219275579
Pubmed

Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.

FBN1 C6

4.47e-0410111230429287
Pubmed

Polymorphism discovery in 62 DNA repair genes and haplotype associations with risks for lung and head and neck cancers.

MLH3 POLK

4.47e-0410111217494052
Pubmed

Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk.

ATR BRCA1

4.47e-0410111237592023
Pubmed

Cdk12 is essential for embryonic development and the maintenance of genomic stability.

ATR BRCA1

4.47e-0410111226658019
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZHX3 NKX6-2 TUT7 ZNF101 ZNF235 IBTK BRD2 BRCA1 HOXD3

4.61e-04709111922988430
Pubmed

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.

NEDD4 BRCA1

5.45e-0411111217996703
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

ZNF138 MFHAS1 CMYA5 ZNF235 NKRF OSBP ZSCAN20

6.28e-04451111736168627
Pubmed

Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.

REV3L BRCA1

6.52e-0412111228700933
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBP OSBPL1A

6.52e-0412111211735225
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBP OSBPL1A

6.52e-0412111212215260
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

MAP4 CCDC168 FSIP2 FBN1

6.66e-04123111426912792
Pubmed

Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.

ATR ATRX

7.69e-0413111219064565
Pubmed

ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.

MYH11 FBN1 BRCA1

8.17e-0457111323788249
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ZHX3 ATR ATRX MAP4 PHRF1 OSBP BRD2 ZNF644 DDX20

8.58e-04774111915302935
Pubmed

PRSS50 is a testis protease responsible for proper sperm tail formation and function.

TEX14 AKAP4

8.96e-0414111233913480
Pubmed

Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan.

DDX20 TARBP2

8.96e-0414111220585341
Pubmed

Expression profiles of active genes in human and mouse livers.

AZGP1 A2ML1

8.96e-041411128863742
Pubmed

Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases.

ATRX REV3L

8.96e-0414111215964851
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP34 PHRF1 REV3L NKRF MLH3 BRD2 BRCA1 CRYBG3 SIPA1L2 TARBP2 BAHCC1

8.99e-0411161111131753913
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZHX3 ATRX CENPC MAP4 SRFBP1 NKRF BRD2 BRCA1 ZNF644 ANKRD11

9.77e-049541111036373674
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

CENPE TUT7 DGKH NKRF IBTK NOP14 ZNF644 TMEM131 DDX20 MRPL3 CRYBG3 GEN1 NEURL4

9.81e-0414961111332877691
Pubmed

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.

ATR BRCA1 GEN1

9.95e-0461111327694478
Pubmed

The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features.

ATR BRCA1

1.03e-0315111219536649
Pubmed

Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex.

ATR BRCA1

1.03e-0315111227073218
Pubmed

α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo.

MYH11 FBN1

1.03e-0315111225670798
Pubmed

CRL4-DCAF8L2 E3 ligase promotes ubiquitination and degradation of BARD1.

NOP14 BRCA1

1.03e-0315111235487060
Pubmed

Structure-function relationship of Vpr: biological implications.

ATR BRCA1

1.18e-0316111219275588
Pubmed

Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.

ATR BRCA1

1.18e-0316111227760317
Pubmed

The interactome of the prostate-specific protein Anoctamin 7.

ATRX MAP4 DDX20

1.20e-0365111332176628
Pubmed

Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice.

LIFR C6

1.33e-031711129175833
Pubmed

Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

ZNF138 ZNF155

1.33e-031711127557990
Pubmed

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.

ANKRD11 DNAH11

1.33e-0317111223502783
Pubmed

Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations.

MYH11 LIFR

1.49e-0318111228334964
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZHX3 ZNF705A ZNF138 ZNF695 ZNF155 ZNF101 ZNF235 ZNF705G ZNF514 ZSCAN10 ZSCAN20 ZNF655 ZNF679

5.24e-06718731328
GeneFamilyAnkyrin repeat domain containing

IBTK ANKRD34B OSBPL1A ANKRD11 ANKRD30A ANKRD12

4.35e-04242736403
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBP OSBPL1A

1.03e-0312732670
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

BDP1 GON4L ZSCAN20

1.28e-0353733532
GeneFamilyDyneins, axonemal

DNAH14 DNAH11

2.10e-0317732536
GeneFamilyDNA polymerases

REV3L POLK

3.85e-0323732535
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

CMYA5 AKAP4

6.08e-0329732396
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ZFYVE16 CENPE PHRF1 BRCA1

6.18e-03181734694
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

ZFYVE16 FGD6

6.93e-033173281
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

USP34 ZHX3 ATR ATRX CENPC ZFYVE16 CENPE MTF2 REV3L NEDD4 IBTK BRCA1 TMEM131 CRYBG3

1.28e-0585610914M4500
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

BDP1 ZNF138 ATR CENPC CENPE TUT7 REV3L BRCA1 ZNF644 OSBPL1A FGF13 POLK

1.87e-0565610912M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

ZHX3 ATR ATRX CENPE MTF2 REV3L NEDD4 IBTK BRCA1 TMEM131

2.54e-0546610910M13522
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

BDP1 ATRX CENPE HPSE2 REV3L FBN1 TBC1D10A ZNF644 FKBP7 ANKRD12 GRIN3A FGD6 DOP1A DOC2B

1.28e-0574410214Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

ATR ENPP3 KBTBD8 TEX14 ZNF235 NKRF NOP14 BRCA1 PRMT9 FGF13 ANKRD12 FGD6 FAM135A DOP1A

3.73e-0582010214gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

BDP1 ATRX CENPE REV3L NKRF TBC1D10A FKBP7 TMEM131 FGD6 FAM135A

4.40e-0543210210Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

BDP1 ZHX3 ATRX FBXW2 REV3L IBTK ZNF644 TRMT13 FAM135A

8.20e-053751029gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

BDP1 ATRX CENPC CENPE NKRF NOP14 ANKRD11 TMEM131 GEN1 JHY

8.72e-0546910210Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

BDP1 ATRX CENPE MAP4 TUT7 GON4L FBXW2 REV3L R3HCC1L BRCA1 ZNF644 SIPA1L2 POLK

9.22e-0578010213Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

BDP1 ATRX CENPE REV3L NKRF BRCA1 FGD6 GEN1

1.29e-043111028Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

ATR MTF2 ENPP3 KBTBD8 TEX14 SRFBP1 NKRF NOP14 BRCA1 PRMT9 ANKRD12 CCL25 FAM135A

1.34e-0481010213gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

USP34 ATRX DGKH NEDD4 LIFR FGD6 FAM135A DOC2B

3.68e-082001108dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

USP34 ZNF155 ATRX SRFBP1 ZNF644 TMEM131 ANKRD12

4.10e-07186110703db813598b67b1e08f759758a1c2023396921fa
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 PAG1 DGKH ZNF644 ANKRD11 TMEM131 ANKRD12

4.40e-071881107ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 PAG1 ENPP3 DGKH LRP8 ANKRD11 ANKRD12

6.03e-07197110757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 USP34 ATRX CENPC ZNF644 ANKRD11 ANKRD12

6.67e-07200110712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

CFAP47 ZNF705A ABCA13 NEK10 FGF13 DNAH11

2.08e-0615111068216462e723fec2797387929dde095370947e10a
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

CENPC R3HCC1L A2ML1 CRYBG3 FAM135A DOC2B

4.87e-0617511060cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

AZGP1 HPSE2 ACSF2 OSBPL1A ANKRD30A FGF13

5.72e-061801106d48a3d27357f7d184132a6805950f93080146b59
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BDP1 USP34 ATRX TUT7 ANKRD11 ANKRD12

8.78e-061941106e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 USP34 ATRX ZNF644 ANKRD11 ANKRD12

1.01e-051991106f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ATRX DGKH LIFR SIPA1L2 FAM135A DOC2B

1.04e-052001106a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 C12orf50 A2ML1 ANKRD30A DOC2B

1.54e-05126110569b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 C12orf50 A2ML1 ANKRD30A DOC2B

1.54e-0512611056cb89754010d64875e115da6c5805efac7a4a82d
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

CFAP47 ABCA13 NEK10 C6 DNAH11

4.29e-05156110510d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATRX NEDD4 FSIP2 IBTK BAHCC1

5.60e-051651105436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATRX NEDD4 FSIP2 IBTK BAHCC1

5.60e-051651105242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCellICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright|ICU-NoSEP / Disease, Lineage and Cell Type

PHRF1 TRDC DNAH14 OSBP CCL25

5.93e-051671105f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH11 CENPE FXYD4 NKRF BRCA1

6.63e-0517111051efce222989460bb59bd9fa955e7d9a60c73994c
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZHX3 ATRX CMYA5 NEDD4 IBTK

7.60e-051761105749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP47 ABCA13 NEK10 C6 DNAH11

8.90e-051821105fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

MYH11 ENPP3 HPSE2 NKRF ZSCAN20

8.90e-051821105ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

HPSE2 ACSF2 OSBPL1A ANKRD30A FGF13

9.13e-051831105b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

HPSE2 ACSF2 OSBPL1A ANKRD30A FGF13

9.13e-0518311053f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA13 AZGP1 CMYA5 TRPM5 A2ML1

9.61e-051851105686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFYVE16 LIFR IRAK4 TRMT13 FAM135A

9.86e-05186110539e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP47 ABCA13 NEK10 C6 DNAH11

9.86e-051861105f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZHX3 ABCA13 MFHAS1 DNAH14 DNAH11

9.86e-051861105f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFYVE16 LIFR IRAK4 TRMT13 FAM135A

9.86e-05186110502418c50fdcca549bf73dedf6199ab4a27862a9b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 DGKH ANKRD34B FGF13 FAM135A

1.01e-04187110587b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 DGKH ANKRD34B FGF13 FAM135A

1.01e-04187110542a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 DGKH ANKRD34B FGF13 FAM135A

1.01e-04187110564afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

HPSE2 ACSF2 OSBPL1A ANKRD30A FGF13

1.04e-0418811054dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

CFAP47 ABCA13 NEK10 C6 DNAH11

1.06e-041891105b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP47 ABCA13 NEK10 C6 DNAH11

1.06e-04189110527329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP47 ABCA13 NEK10 C6 DNAH11

1.06e-0418911053e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 MFHAS1 DGKH DNAH14 FGF13

1.09e-0419011053fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 ATRX MAP4 FBN1 ANKRD11

1.09e-041901105d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP47 ABCA13 NEK10 C6 DNAH11

1.12e-041911105e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP47 ABCA13 NEK10 C6 DNAH11

1.12e-0419111059d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP47 ABCA13 NEK10 C6 DNAH11

1.12e-0419111051c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA13 AZGP1 CMYA5 TRPM5 CCL25

1.14e-041921105d6ea34391c3f730684b82e912d9cf55e928b3311
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP47 ABCA13 NEK10 C6 DNAH11

1.14e-041921105eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP34 ATR ATRX ZFYVE16 CRYBG3

1.17e-041931105abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DGKH NEDD4 LIFR SIPA1L2 FAM135A

1.17e-041931105e1d546165dcc2392f540162206852c4717d7306f
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PAG1 ENPP3 DGKH ANKRD12 MASP2

1.17e-0419311059337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPE ABCA13 FBN1 OSBPL1A DOC2B

1.17e-041931105ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CENPE ABCA13 FBN1 OSBPL1A DOC2B

1.20e-04194110523318a1b55895b5166c6151f488a94a09b4627ff
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PAG1 MFHAS1 DGKH ZNF101 ANKRD12

1.23e-04195110522191d361af136942508f1553ff41a626ed982ad
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

BDP1 ATRX CENPE TUT7 ANKRD12

1.29e-0419711050fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYH11 TDRD9 MAP4 HPSE2 CMYA5

1.32e-041981105cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

ATRX REV3L OSBPL1A ANKRD11 ANKRD12

1.35e-041991105fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

ATRX REV3L ZNF644 ANKRD11 ANKRD12

1.35e-041991105c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ATRX HPSE2 LIFR FGF13 CRYBG3

1.35e-041991105615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

CFAP47 ABCA13 NEK10 C6 DNAH11

1.38e-042001105f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP47 ABCA13 NEK10 C6 DNAH11

1.38e-042001105ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CFAP47 ABCA13 NEK10 C6 DNAH11

1.38e-042001105a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP47 ABCA13 NEK10 C6 DNAH11

1.38e-042001105918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright|ICU-NoSEP / Disease, condition lineage and cell class

PHRF1 TRDC DNAH14 OSBP CCL25

1.38e-042001105c2df917900872453ea17a39928e39d071a6d3339
DrugClorgyline

BDP1 ZNF138 ATRX CENPC ZFYVE16 TUT7 REV3L IBTK ZNF644 ANKRD12 POLK

3.85e-1016810611ctd:D003010
DiseaseCREST syndrome (is_implicated_in)

CENPC FBN1

1.21e-0521032DOID:0060218 (is_implicated_in)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

MYH11 FBN1

5.33e-04101032cv:C4707243
Diseaseurate measurement, bone density

ZNF695 DNAH14 FSIP2 A2ML1 ANKRD11 FAM135A JHY DNAH11

1.49e-036191038EFO_0003923, EFO_0004531
DiseaseChronic myeloproliferative disorder

ATR CENPE

1.99e-03191032C1292778
Diseasenucleotide measurement

APTX SIPA1L2 ZNF679

2.15e-03731033EFO_0010513
DiseaseSeckel syndrome

ATR CENPE

2.66e-03221032C0265202
Diseasestomach carcinoma (is_marker_for)

AZGP1 BRCA1

3.17e-03241032DOID:5517 (is_marker_for)
Diseasebreast cancer (implicated_via_orthology)

ATR BRCA1

3.44e-03251032DOID:1612 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LDHEGVTSPKNKTCK

BAHCC1

2241

Q9P281
VQAGPSKGEKHKNKC

BDP1

486

A6H8Y1
PHAVKKLSSGNSKLS

CCL25

111

O15444
HLLLQPKTKGESANC

PRMT9

276

Q6P2P2
CQKGTPNSASKTKDK

ANKRD11

146

Q6UB99
VCISEKNLPGHSKNT

CRYBG3

1501

Q68DQ2
LKAGSHDPKCRNQSL

AKAP4

451

Q5JQC9
SEKPSGKRQCKTKHL

BCORP1

96

Q8N888
EKTHSSLLCPKGKVA

A2ML1

911

A8K2U0
SNSGQCSVPLKKGKD

APTX

156

Q7Z2E3
SQKDVCLPKATHQKE

ANKRD30A

576

Q9BXX3
SKGAQPKQVTCHLAK

DNAH11

1641

Q96DT5
VLNIKKPLCSSNGSH

ABCA13

1441

Q86UQ4
LENHKPCSSKARQKI

DOP1A

2436

Q5JWR5
KKHLNSKTVGQCLET

ACSF2

66

Q96CM8
NTKQKLPVKSHSECG

DDX20

511

Q9UHI6
GKSPKHSCGLSEKQS

ANKRD12

541

Q6UB98
HSCGLSEKQSTPLKQ

ANKRD12

546

Q6UB98
ATLKNGKKACLNPAS

CXCL3

76

P19876
LSLQDGHKAKKPACK

MTF2

31

Q9Y483
IKPENHCSKLSGNTK

R3HCC1L

601

Q7Z5L2
ITTAKLPCGKHTTKQ

ANKRD34B

151

A5PLL1
SSKCGSKANIKHKPG

MAP4

1036

P27816
IRKQCKHQNGLKSST

JHY

366

Q6NUN7
SLKHNCSKGGPSQLL

NEDD4

471

P46934
VISPCSKKNVGEKHR

MFHAS1

1036

Q9Y4C4
HLIANQGCPRSKLSK

EURL

66

Q9NYK6
SRQKCGATPKSHLGK

IBTK

1131

Q9P2D0
QKKSKLHGPTETSSC

CD33

311

P20138
ISVKEEHGCLPNSKK

ARNTL2

291

Q8WYA1
QDGTHASPKNKKKTS

FSIP2

326

Q5CZC0
KDTNKLSCQQHKTDP

FSIP2

846

Q5CZC0
KKSVVPECHLNDSKT

FAM135A

856

Q9P2D6
CNLKSEIKKLSQGSP

NEK10

1076

Q6ZWH5
TLSKESGQLPNKKNC

MLH3

661

Q9UHC1
QKICHSKSGEINPVK

PHRF1

1601

Q9P1Y6
KDQKAKGILHSPASQ

HOXD3

251

P31249
DKQKCDSGKPVLRTH

DGKH

961

Q86XP1
VALDKQKGCKIAQHP

HPSE2

156

Q8WWQ2
KCNHPSLAEGNKAKL

NOP14

456

P78316
INHKTGDKCVLNFKP

OSBPL1A

731

Q9BXW6
VNHKTGDKCNLKFVP

OSBP

601

P22059
KHSGKKQTVPCLDIV

KBTBD8

296

Q8NFY9
LHSSNDTVPIKFKKC

GRIN3A

561

Q8TCU5
QSLPGSNCKHPEIKK

BRCA1

1096

P38398
SPKKTSSNCNGEEKK

ATRX

316

P46100
CHFPKGIKQIKNGTT

ATRX

1026

P46100
FQALKAEKCPHSKSN

ATR

1596

Q13535
AEKCPHSKSNRNKVD

ATR

1601

Q13535
HRPENCSKTSKKGDL

FKBP7

41

Q9Y680
NALHCTITKAKGLKP

DOC2B

141

Q14184
LTKLKGHCQLGQKQS

C6

766

P13671
IQSPSKECQKSHPKS

CENPC

71

Q03188
MPNINKLKTCGIHSK

ENPP3

181

O14638
CKCPAGHKLNEVSQK

FBN1

271

P35555
EGGKCSSPKSRNHSK

FBN1

2066

P35555
PGQLKAAVSSKDHTC

CMYA5

1926

Q8N3K9
SIDCSPHKTVKKTAN

GON4L

771

Q3T8J9
KDCPHVREKGSGKQN

ELMO3

606

Q96BJ8
KQSIPSTSQKCKHPE

DNAH14

3296

Q0VDD8
QGHLPLKSFTAVCQK

MASP2

336

O00187
PSKGKTSCDKNKLNV

FGF13

31

Q92913
HKKENNSGTCLDSPL

GEN1

881

Q17RS7
SVASQCLHEKKNKRP

IRAK4

431

Q9NWZ3
KCGHFLQKQNKSPDT

CCDC168

571

Q8NDH2
LPKHSKLNTIAVCKN

CCDC168

6641

Q8NDH2
LQKCKVKSLLHSPGD

FBXW2

276

Q9UKT8
GSLQCQLQHKEKKLS

EFCAB3

31

Q8N7B9
NNKLTCHLSFKSSKP

CFAP47

1376

Q6ZTR5
AHKQVTCENSPKSPK

CENPE

2596

Q02224
HEKCGTLIKLSNNNK

NEURL4

321

Q96JN8
QVNSQKKGAPHDLKC

LIFR

41

P42702
KKGAPHDLKCVTNNL

LIFR

46

P42702
TKNCKAAAGKSPSLI

LRP8

411

Q14114
LHPACSQKKCAKQGD

PLEKHM2

336

Q8IWE5
KPCKENFTGSETLKH

NXF2

376

Q9GZY0
GHKNCLVKVKDSKLP

MRPL3

291

P09001
CKCKSSQKQHSPVPE

FXYD4

61

P59646
LNDPKNGDSATKHLK

TRMT13

151

Q9NUP7
ATAEKCLHKINGKPL

TRNAU1AP

56

Q9NX07
SSFKEASCKTPKINH

TEX14

1191

Q8IWB6
STNKLGTPNCKAELH

TDRD9

1136

Q8NDG6
KRHLSTCDGQNPPKK

NKRF

31

O15226
KKHKPSNLALVSPCG

NKX6-2

256

Q9C056
KDGSCKDSPNKLSHI

SIPA1L2

1201

Q9P2F8
KDSPNKLSHIGDKSC

SIPA1L2

1206

Q9P2F8
LDSQDSTGKPKCHQS

PAG1

116

Q9NWQ8
SKKGKLSEQLKHCNG

BRD2

341

P25440
ISKCSNTKDNKDSPH

C12orf50

226

Q8NA57
EKLCTEQGSHPKFQK

MYH11

551

P35749
EKGCASQVPSHSPKK

ZSCAN10

96

Q96SZ4
LTHSGKKPYVSKQCG

ZNF705A

136

Q6ZN79
LNKCKISHTGEKPFK

ZNF695

171

Q8IW36
QCGKVFKQSPTLTKH

ZNF138

226

P52744
GQSQKKGVKNTCPDL

ZSCAN20

171

P17040
LKALVKACKSHSQEP

TRPM5

331

Q9NZQ8
HKENSKKEILPVSSC

REV3L

641

O60673
KESSCHSSVKEQKPL

SRFBP1

296

Q8NEF9
GNNSQRTHPEKKSCK

ZNF514

191

Q96K75
CGKAFSVPSKLNNHK

ZNF723

206

P0DPD5
GKSGHDNLQVKTCKS

ZNF679

116

Q8IYX0
QPNGSKHKLTKAASL

TMEM131

1636

Q92545
PKQLKLTCNEHLQSG

FGD6

456

Q6ZV73
NKHSKEECSSLPSKS

POLK

721

Q9UBT6
SNLNKHQKTHTGEKP

ZNF840P

346

A6NDX5
LTHSGKKPYVSKQCG

ZNF705EP

136

A8MWA4
SKQCGKSLSNLLSPK

ZNF705EP

146

A8MWA4
LTHSGKKPYVSKQCG

ZNF705G

136

A8MUZ8
DKESGVHKPKDCQTS

ZNF644

51

Q9H582
VTSHQAPGEKKKLKC

AZGP1

211

P25311
DKSCSPSSGIIQHKK

ZNF655

281

Q8N720
IPDCHLNKKSQTGVK

ZNF101

86

Q8IZC7
ENTKQPSKSCHKPKA

TRDC

101

B7Z8K6
KPSQGGKCKQSISDV

ZNF155

146

Q12901
TSCTGQGPSKKAAKH

TARBP2

71

Q15633
SLKDRQQPKCKSHSS

USP34

1826

Q70CQ2
KRSSHSGNGCKNEKL

SC5D

276

O75845
HIKKECPQFKGSSGS

TUT7

1461

Q5VYS8
LKHALGSPEKVKACQ

TBC1D10A

311

Q9BXI6
SNKLAEQLPGKVSCK

ZHX3

756

Q9H4I2
LGKKSPACSTHEKDT

ZNF235

286

Q14590
KLQHKSQPCGLLKDV

ZFYVE16

261

Q7Z3T8
ALCPHLKTLKSNGMN

ZFYVE16

1461

Q7Z3T8