Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenowide sternum

FAT4 PDGFRA DCHS1

3.11e-065963MP:0012279
DomainCyt_P450_E_grp-I_CYP1

CYP1A1 CYP1A2

4.30e-0521232IPR008066
DomainTox-GHH_dom

TENM3 TENM1

2.56e-0441232IPR028916
DomainTox-GHH

TENM3 TENM1

2.56e-0441232PF15636
DomainTen_N

TENM3 TENM1

2.56e-0441232IPR009471
DomainTen_N

TENM3 TENM1

2.56e-0441232PF06484
DomainTENEURIN_N

TENM3 TENM1

2.56e-0441232PS51361
DomainEGF_1

FAT4 RELN LAMA5 MUC12 ITGB5 TENM3 VCAN TENM1

2.88e-042551238PS00022
DomainEGF-like_CS

FAT4 RELN LAMA5 MUC12 ITGB5 TENM3 VCAN TENM1

3.37e-042611238IPR013032
DomainEGF_2

FAT4 RELN LAMA5 MUC12 ITGB5 TENM3 VCAN TENM1

3.73e-042651238PS01186
DomainYD

TENM3 TENM1

4.25e-0451232IPR006530
DomainFAD_binding_1

NDOR1 MTRR

6.34e-0461232PF00667
Domain-

NDOR1 MTRR

6.34e-04612321.20.990.10
DomainFAD-binding_1

NDOR1 MTRR

6.34e-0461232IPR003097
DomainNADPH_Cyt_P450_Rdtase_dom3

NDOR1 MTRR

6.34e-0461232IPR023173
DomainEGF_extracell

RELN ITGB5 TENM3 TENM1

6.57e-04601234IPR013111
DomainEGF_2

RELN ITGB5 TENM3 TENM1

6.57e-04601234PF07974
PathwayWP_ESTROGEN_METABOLISM_WP697

CYP1A1 CYP1A2 UGT1A6 ARSL

3.70e-0618864M39424
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC12 MUC6

1.16e-0416863M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC12 MUC6

1.40e-0417863M27412
Pubmed

Defining the membrane proteome of NK cells.

EPS15 GAK PDGFRA LSG1 AKNA DGKA IFI16 BIRC6 F5 ANKRD27 PRDX6 NBAS AAAS GANAB KIDINS220 HPS6 TMPO PRKDC EIF3F EIF2AK3

9.49e-0911681272019946888
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NDOR1 SETD1B DUSP5 AKNA LAMA5 TESK1 BIRC6 ITGB5 MADD PLEKHH3 SBNO2 MAPK8IP3 MST1R WIZ TTLL4 HPS6 TANC1 PRKDC CABIN1

2.17e-0811051271935748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PDGFRA KIF26B LSG1 SPECC1 TESK1 VIRMA ANKRD27 MADD ZNF106 BMPR2 ALMS1 SYNE2 TET1 NHS TANC1 CRYBG3

1.10e-078611271636931259
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

VGF TPR EPS15 NHSL2 LSG1 ZNF318 VIRMA MAPK8IP3 WIZ KCNB1 SRGAP3 SYNE2 DCHS1 CABIN1 KCNT1 CDH10

4.89e-079631271628671696
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 MXRA5 KIF26B DGKA BIRC6 IGSF10 ARHGAP5 AFAP1L2 WIZ SRGAP3 MYO3B PCIF1 TMPO PRKDC

5.47e-077361271429676528
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

LAMA5 NCKAP5 BIRC6 WAC SCRN2 ZNF106 CCNYL1 TMPO NHS CABIN1

9.61e-073631271014691545
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

KIF26B LSG1 KIDINS220 ALMS1 NHS TANC1 CRYBG3 CEP97

1.08e-06209127836779422
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

EPS15 GAK LSG1 CHAF1A BIRC6 MADD NBAS ZNF106 AAAS ALMS1 TTLL4 PRR14L TANC1

3.06e-067331271334672954
Pubmed

TGFB1 induces fetal reprogramming and enhances intestinal regeneration.

NDOR1 PDGFRA PRKDC

3.93e-069127337865088
Pubmed

Polymorphisms in phase I and phase II metabolism genes and risk of chronic benzene poisoning in a Chinese occupational population.

CYP1A1 CYP1A2 UGT1A6

5.60e-0610127318784359
Pubmed

Recombination suppression by heterozygous Robertsonian chromosomes in the mouse.

RELN SGK3 MLPH

5.60e-061012738454207
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

KIAA1549 ZNF318 KIDINS220 ALMS1 TENM1 NHS TANC1 CRYBG3

5.93e-06263127834702444
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

TPR SETD1B PDGFRA CHAF1A MUC12 BIRC6 VIRMA INO80D ITGB5 WAC SCRN2 NBAS ZNF106 AAAS GANAB NHS MTO1

7.06e-0613271271732694731
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

GAK RUSC1 TESK1 ANKRD27 AAAS KIDINS220 WIZ TMPO

1.06e-05285127834369648
Pubmed

Methylation differences in the murine P1450 and P3450 genes in wild-type and mutant hepatoma cell culture.

CYP1A1 CYP1A2

1.32e-05212722425809
Pubmed

Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.

CYP1A1 CYP1A2

1.32e-05212723000715
Pubmed

Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone.

CYP1A1 CYP1A2

1.32e-052127212147246
Pubmed

Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS.

CYP1A1 CYP1A2

1.32e-052127217852022
Pubmed

Cyp1a2 protects against reactive oxygen production in mouse liver microsomes.

CYP1A1 CYP1A2

1.32e-052127214980704
Pubmed

Immunocytochemical study of cytochrome P450 (1A1/1A2) induction in murine ocular tissues.

CYP1A1 CYP1A2

1.32e-05212727781742
Pubmed

Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.

CYP1A1 CYP1A2

1.32e-052127211207026
Pubmed

Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues.

CYP1A1 CYP1A2

1.32e-05212723785172
Pubmed

Assignment of dioxin-inducible cytochrome P-450 gene family to Chinese hamster chromosome 4.

CYP1A1 CYP1A2

1.32e-05212723860967
Pubmed

Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype.

CYP1A1 CYP1A2

1.32e-052127216609368
Pubmed

Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.

CYP1A1 CYP1A2

1.32e-052127215094312
Pubmed

The RON receptor tyrosine kinase regulates IFN-gamma production and responses in innate immunity.

IFNGR1 MST1R

1.32e-052127218684919
Pubmed

PERK inhibition attenuates vascular remodeling in pulmonary arterial hypertension caused by BMPR2 mutation.

BMPR2 EIF2AK3

1.32e-052127233500333
Pubmed

CYP1A1 and CYP1A2 expression: comparing 'humanized' mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell lines.

CYP1A1 CYP1A2

1.32e-052127219285097
Pubmed

[Association of polymorph variants of CYP1A2 and CYP1A1 genes with reproductive and thyroid diseases in female workers of petrochemical industry].

CYP1A1 CYP1A2

1.32e-052127222855999
Pubmed

Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 gene.

CYP1A1 CYP1A2

1.32e-052127212438513
Pubmed

Inhibition of ron kinase blocks conversion of micrometastases to overt metastases by boosting antitumor immunity.

MST1R PRKDC

1.32e-052127223612011
Pubmed

Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line.

CYP1A1 CYP1A2

1.32e-052127221262253
Pubmed

The nuclear factor of activated T cells 5 (NFAT5) contributes to the renal corticomedullary differences in gene expression.

NDOR1 NFAT5

1.32e-052127236433977
Pubmed

Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells.

CYP1A1 CYP1A2

1.32e-052127226953171
Pubmed

Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition.

CYP1A1 CYP1A2

1.32e-052127218493746
Pubmed

Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2.

CYP1A1 CYP1A2

1.32e-052127232726451
Pubmed

A shuffled CYP1A library shows both structural integrity and functional diversity.

CYP1A1 CYP1A2

1.32e-052127217823232
Pubmed

Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes.

CYP1A1 CYP1A2

1.32e-05212723988744
Pubmed

CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures.

CYP1A1 CYP1A2

1.32e-052127226643992
Pubmed

Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions.

FAT4 DCHS1

1.32e-052127225355906
Pubmed

PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis.

NDOR1 EIF2AK3

1.32e-052127223071091
Pubmed

Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism.

CYP1A1 CYP1A2

1.32e-052127222949628
Pubmed

Increased basal expression of hepatic Cyp1a1 and Cyp1a2 genes in inbred mice selected for susceptibility to acetaminophen-induced hepatotoxicity.

CYP1A1 CYP1A2

1.32e-05212729295056
Pubmed

Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury.

CYP1A1 CYP1A2

1.32e-052127225680282
Pubmed

Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A.

CYP1A1 CYP1A2

1.32e-052127225703676
Pubmed

Developmental and tissue-specific differential regulation of the mouse dioxin-inducible P1-450 and P3-450 genes.

CYP1A1 CYP1A2

1.32e-05212724054433
Pubmed

Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice.

CYP1A1 CYP1A2

1.32e-052127231147315
Pubmed

Aryl hydrocarbon (Ah) receptor-independent induction of Cyp1a2 gene expression by acenaphthylene and related compounds in B6C3F1 mice.

CYP1A1 CYP1A2

1.32e-05212728001243
Pubmed

Metabolism of 4-n-nonylphenol by non-modified and CYP1A1- and CYP1A2-transgenic cell cultures of tobacco.

CYP1A1 CYP1A2

1.32e-052127216402549
Pubmed

The effect of CYP1A1 and CYP1A2 polymorphisms on gastric cancer risk among different ethnicities: a systematic review and meta-analysis.

CYP1A1 CYP1A2

1.32e-052127224443269
Pubmed

Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: differential regulation in primary human hepatocytes versus transformed human cells.

CYP1A1 CYP1A2

1.32e-052127216426572
Pubmed

The influence of CYP1A1 and CYP1A2 polymorphisms on stroke risk in the Chinese population.

CYP1A1 CYP1A2

1.32e-052127233046100
Pubmed

IL16 and factor V gene variations are associated with asparaginase-related thrombosis in childhood acute lymphoblastic leukemia patients.

IL16 F5

1.32e-052127236946317
Pubmed

CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification.

CYP1A1 CYP1A2

1.32e-052127219276377
Pubmed

A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia.

IFNGR1 SYNE2

1.32e-052127226066746
Pubmed

Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

CYP1A1 CYP1A2

1.32e-052127217052995
Pubmed

Differences in regulation of gene expression between Cyp1a-1 and Cyp1a-2 in adult mouse hepatocytes in primary culture.

CYP1A1 CYP1A2

1.32e-05212721335375
Pubmed

Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.

CYP1A1 CYP1A2

1.32e-05212728095225
Pubmed

A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes.

CYP1A1 CYP1A2

1.32e-052127216505155
Pubmed

Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2.

CYP1A1 CYP1A2

1.32e-05212728274012
Pubmed

Species difference among experimental rodents in induction of P450IA family enzymes by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

CYP1A1 CYP1A2

1.32e-05212721452456
Pubmed

Structure of the planar cell polarity cadherins Fat4 and Dachsous1.

FAT4 DCHS1

1.32e-052127236797229
Pubmed

Amino-terminal sequence and structure of monoclonal antibody immunopurified cytochromes P-450.

CYP1A1 CYP1A2

1.32e-05212723718958
Pubmed

Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele.

CYP1A1 CYP1A2

1.32e-052127214637164
Pubmed

Comparison of mouse hepatic mitochondrial versus microsomal cytochromes P450 following TCDD treatment.

CYP1A1 CYP1A2

1.32e-052127216516144
Pubmed

Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date.

CYP1A1 CYP1A2

1.32e-052127228698457
Pubmed

Mammalian cadherins DCHS1-FAT4 affect functional cerebral architecture.

FAT4 DCHS1

1.32e-052127225930014
Pubmed

[Association of cytochrome P450 genes polymorphisms (CYP1A1 and CYP1A2) with the development of chronic obstructive pulmonary disease in Bashkortostan].

CYP1A1 CYP1A2

1.32e-052127218389617
Pubmed

Generation of a conditional knockout allele for the NFAT5 gene in mice.

NDOR1 NFAT5

1.32e-052127225601839
Pubmed

Isolation and characterization of full-length mouse cDNA and genomic clones of 3-methylcholanthrene-inducible cytochrome P1-450 and P3-450.

CYP1A1 CYP1A2

1.32e-05212726548461
Pubmed

Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer.

CYP1A1 CYP1A2

1.32e-052127234242741
Pubmed

Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery.

CYP1A1 CYP1A2

1.32e-052127210623596
Pubmed

Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate.

CYP1A1 CYP1A2

1.32e-052127221081470
Pubmed

Genetic variation of genes for xenobiotic-metabolizing enzymes and risk of bronchial asthma: the importance of gene-gene and gene-environment interactions for disease susceptibility.

CYP1A1 CYP1A2 UGT1A6

2.10e-0515127319575027
Pubmed

Platelet storage pool deficiency in mouse pigment mutations associated with seven distinct genetic loci.

SGK3 HPS6 MLPH

2.10e-051512736696991
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TPR EPS15 RUSC1 ZNF318 BIRC6 WIZ ALMS1 TET1 CRYBG3

2.44e-05418127934709266
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FBF1 AKNA KIAA1549 LAMA5 CLOCK ANKRD27 TTLL4 TET1 ANKIB1 KCNT1

2.60e-055291271014621295
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

DUSP5 KIAA1549 BIRC6 MADD ARHGAP5 AAAS GANAB WIZ SYNE2 TMPO SLC39A6 NHS TANC1 CRYBG3

3.10e-0510491271427880917
Pubmed

Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development.

FAT4 PDGFRA DCHS1

3.11e-0517127332155439
Pubmed

Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women.

CYP1A1 CYP1A2 UGT1A6

3.11e-0517127319424794
Pubmed

Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.

CYP1A1 CYP1A2 F5 MTRR

3.16e-0549127418936436
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC12 MUC6

3.73e-0518127318834073
Pubmed

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.

CYP1A1 CYP1A2

3.96e-053127217997381
Pubmed

Doublefoot: a new mouse mutant affecting development of limbs and head.

SGK3 MLPH

3.96e-05312729062079
Pubmed

CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD.

CYP1A1 CYP1A2

3.96e-053127220080081
Pubmed

Ah receptor, CYP1A1, CYP1A2 and CYP1B1 gene polymorphisms are not involved in the risk of recurrent pregnancy loss.

CYP1A1 CYP1A2

3.96e-053127215299091
Pubmed

Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes.

A1BG F5

3.96e-053127223690342
Pubmed

Genetic factors in catechol estrogen metabolism in relation to the risk of endometrial cancer.

CYP1A1 CYP1A2

3.96e-053127215734958
Pubmed

Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk.

CYP1A1 CYP1A2

3.96e-053127224668907
Pubmed

Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of colorectal cancer: a hospital-based case-control study in Japan.

CYP1A1 CYP1A2

3.96e-053127219452301
Pubmed

Meat intake, metabolic genes and colorectal cancer.

CYP1A1 CYP1A2

3.96e-053127212484238
Pubmed

Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1.

CYP1A1 CYP1A2

3.96e-053127238081439
Pubmed

Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction.

CYP1A1 CYP1A2

3.96e-053127224497629
Pubmed

CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells.

CYP1A1 CYP1A2

3.96e-053127219666078
Pubmed

Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.

CYP1A1 CYP1A2

3.96e-053127218814841
Pubmed

Contributions of the three CYP1 monooxygenases to pro-inflammatory and inflammation-resolution lipid mediator pathways.

CYP1A1 CYP1A2

3.96e-053127223956430
Pubmed

Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.

NDOR1 NFAT5

3.96e-053127228803730
Pubmed

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.

CYP1A1 CYP1A2

3.96e-053127221357676
Pubmed

FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth.

NDOR1 PRKDC

3.96e-053127232187554
Pubmed

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.

MUC16 MUC12

3.96e-053127226770020
InteractionRHOC interactions

FAT4 LSG1 FBF1 SPECC1 ITGB5 IFNGR1 ARHGAP5 BMPR2 AAAS GANAB KIDINS220 SYNE2 TMPO SLC39A6 EIF2AK3

3.42e-0658412515int:RHOC
InteractionSYNE3 interactions

GALNT14 GAK FBF1 ZNF318 NBAS AAAS GANAB KIDINS220 ALMS1 SYNE2 CRYBG3 EIF2AK3 CEP97

3.95e-0644412513int:SYNE3
InteractionRAC3 interactions

FAT4 KIF26B KIAA1549 SPECC1 IFNGR1 ARHGAP5 BMPR2 AAAS KIDINS220 TENM3 TMPO SLC39A6 NHS TANC1 EIF2AK3

6.91e-0661912515int:RAC3
InteractionRND2 interactions

KIF26B KIAA1549 IFNGR1 ARHGAP5 BMPR2 AAAS GANAB KIDINS220 SYNE2 TMPO SLC39A6 EIF2AK3

1.92e-0544012512int:RND2
InteractionRND1 interactions

KIF26B KIAA1549 ARHGAP5 BMPR2 GANAB KIDINS220 TMPO SLC39A6 NFAT5

2.32e-052461259int:RND1
InteractionABTB2 interactions

ZNF318 BIRC6 VIRMA ZNF106 MTO1 CEP97

3.95e-051011256int:ABTB2
InteractionRHOA interactions

FAT4 LSG1 KIAA1549 CLOCK SPECC1 VIRMA PRDX6 IFNGR1 ARHGAP5 BMPR2 AAAS GANAB KIDINS220 TENM3 SYNE2 TMPO SLC39A6 NHS PRKDC EIF2AK3

4.77e-05119912520int:RHOA
GeneFamilyCD molecules|Mucins

MUC16 MUC12 MUC6

1.13e-0421823648
GeneFamilyCytochrome P450 family 1

CYP1A1 CYP1A2

1.21e-0448221000
CoexpressionLEIN_CEREBELLUM_MARKERS

IL16 ARHGAP5 AFAP1L2 SYNE2 SEBOX KCNT1

3.67e-06851276M1723
CoexpressionLEIN_CEREBELLUM_MARKERS

IL16 ARHGAP5 AFAP1L2 SYNE2 SEBOX KCNT1

3.67e-06851276MM720
CoexpressionHARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_DN

CASS4 FAT4 IL16 NHSL2 SPECC1 ITGB5 SLC47A2 IFNGR1 LDHD VCAN TENM1 FCRLB NHS EIF3F

1.48e-0574012714M41202
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

BIRC6 ZNF106 BMPR2 SRGAP3 TTLL4 PRR14L NFAT5

2.86e-051801277M8239
CoexpressionGSE21546_UNSTIM_VS_ANTI_CD3_STIM_ELK1_KO_DP_THYMOCYTES_UP

THEMIS2 FBF1 IFI16 SPATA1 MYO3B IFI44L HERC6

4.04e-051901277M7537
CoexpressionGSE12366_GC_VS_NAIVE_BCELL_DN

IL16 SETD1B DGKA IFI16 INO80D IFNGR1 HERC6

4.77e-051951277M3170
CoexpressionGSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP

CYP1A2 NDOR1 KIF26B ZNF318 CLOCK MAPK8IP3 SYNE2

5.08e-051971277M8983
CoexpressionGSE41867_NAIVE_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN

CASS4 GAK INO80D SGK3 ZNF106 PCIF1 NFAT5

5.42e-051991277M9498
CoexpressionGSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP

SPECC1 VIRMA ATP10D PLEKHH3 MST1R MSANTD4 CRYBG3

5.59e-052001277M8500
CoexpressionGSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_UP

CYP1A1 DGKA ZNF318 MAPK8IP3 IFNGR1 NBAS TMPO

5.59e-052001277M6836
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VGF GALNT14 RELN KIF26B ITGB5 TENM3 TENM1 NHS

6.74e-08187127885f1678338a47d91e296f0620d4887f057eb7e70
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN NHSL2 KIF26B ITGB5 TENM3 TENM1 TANC1

8.94e-0819412781bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

GALNT14 ABCA13 KIF26B MARK1 DUSP5 MUC16 NHS

4.65e-0716412776e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 DUSP5 DGKA MUC16 ATP10B SRGAP3 TANC1

8.39e-0717912776e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 RELN NHSL2 KIF26B F5 TENM3 VCAN

9.03e-0718112775f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 RELN NHSL2 KIF26B F5 TENM3 VCAN

9.03e-071811277c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT14 ABCA13 KIAA1549 SLC47A2 SYNE2 TENM1 NHS

9.72e-0718312776878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 KIAA1549 NCKAP5 SLC47A2 SYNE2 TENM1 NHS

1.12e-061871277dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 KIAA1549 NCKAP5 SLC47A2 SYNE2 TENM1 NHS

1.12e-061871277f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

GALNT14 ABCA13 MUC16 PLEKHG4B SRGAP3 NHS MLPH

1.25e-06190127751ca9ef4df3220487152fcf684147730637c7cc1
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN KIF26B ITGB5 TENM3 TENM1 TANC1

1.39e-061931277e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN KIF26B ITGB5 TENM3 TENM1 TANC1

1.39e-061931277658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

MXRA5 PDGFRA NHSL2 KIF26B TENM3 VCAN NHS

1.59e-061971277f1c8936986123a3151140c374fcd62d6705c530b
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CASS4 FAT4 IL16 KIF26B TENM3 VCAN TANC1

1.59e-061971277f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellmild-CD4+_Tcm|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TPR DGKA ARHGAP5 SYNE2 LPIN2 IFI44L HERC6

1.70e-06199127706c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 IL16 MXRA5 PDGFRA VCAN MYO3B TENM1

1.76e-062001277fb53be20392a8309a7393774c774a1b1aec6e676
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 ABCA13 VCAN SYNE2 TENM1 NHS

7.69e-0616412761cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 MXRA5 PDGFRA VCAN TANC1 CRYBG3

9.12e-061691276c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR CLOCK IGSF10 ARHGAP5 ZNF106 BMPR2

1.15e-051761276749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT14 RELN KIF26B TENM3 SYNE2 NHS

1.23e-051781276544379f5a6145429762258d426b876bb36c112f5
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT14 NCKAP5 SLC47A2 SYNE2 TENM1 NHS

1.31e-051801276358923e4228035a3e90e2957392089219e90dcd7
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAF1A KIAA1549 NCKAP5 IGSF10 VCAN SLC39A6

1.35e-0518112764e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAF1A KIAA1549 NCKAP5 IGSF10 VCAN SLC39A6

1.35e-051811276ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAF1A KIAA1549 NCKAP5 IGSF10 VCAN SLC39A6

1.35e-0518112763a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SPECC1 F5 LDHD AFAP1L2 MLPH

1.43e-051831276876b4f128c2168fdae7488201ff44f19c06c8415
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SPECC1 F5 LDHD AFAP1L2 MLPH

1.43e-051831276b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

GALNT14 ABCA13 KIAA1549 SLC47A2 SYNE2 NHS

1.48e-05184127651ed1ebfdef45149541917c66cbacad87072e51f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

FAT4 PDGFRA ATP10D ZNF106 TENM3 CRYBG3

1.48e-05184127667164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN KIF26B ITGB5 TENM1 NHS

1.48e-0518412767f6c8912677764d438ab0555faca344d74c2f483
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDGFRA ATP10B NCKAP5 NSUN7 VCAN TANC1

1.53e-051851276efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PDGFRA MARK1 NCKAP5 IGSF10 MLPH

1.53e-051851276f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDGFRA ATP10B NCKAP5 AFAP1L2 VCAN TANC1

1.53e-0518512762e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 RELN NHSL2 KIF26B F5 TENM3

1.53e-05185127634fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PDGFRA MARK1 NCKAP5 IGSF10 MLPH

1.53e-05185127640e958511790e84321da5ccf735f9974c06a0263
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDGFRA ATP10B NCKAP5 AFAP1L2 VCAN TANC1

1.53e-0518512767aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PDGFRA MARK1 NCKAP5 IGSF10 MLPH

1.53e-0518512765f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDGFRA ATP10B NCKAP5 NSUN7 VCAN TANC1

1.53e-051851276fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 RELN NHSL2 KIF26B F5 TENM3

1.53e-0518512768816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VGF RELN KIF26B ITGB5 TENM3 TENM1

1.57e-05186127696f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 KIF26B NCKAP5 SLC47A2 SYNE2 NHS

1.57e-051861276b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEMIS2 A1BG RELN KIF26B DUSP5 TENM3

1.62e-051871276d69f4eee0304a7db226275ab77fc9d5d2b6f3a07
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 ABCA13 MAPK8IP3 SYNE2 TENM1 NHS

1.62e-051871276c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

KIAA1549 NCKAP5 INO80D SLC47A2 SYNE2 NHS

1.62e-051871276738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

DGKA IFI16 SYNE2 LPIN2 IFI44L HERC6

1.67e-0518812766f8946d4710f6e32c937213f99b790b098b8819c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 KIAA1549 NCKAP5 SLC47A2 TENM1 NHS

1.72e-051891276204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 KIF26B NCKAP5 SLC47A2 LPIN2 NHS

1.72e-0518912763b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 KIAA1549 NCKAP5 SLC47A2 TENM1 NHS

1.72e-05189127613fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 SLC47A2 TENM3 VCAN SYNE2 NHS

1.72e-05189127628b502611829e4a24caff2562545c7db97686099
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B AKNA TENM3 TENM1 NHS TANC1

1.77e-05190127626843ec1d19ac85a50990705353b802745d33e4d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B TENM3 MYO3B TENM1 NHS TANC1

1.77e-0519012760acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 AFAP1L2 SRGAP3 SLC39A6 NFAT5 MUC6

1.77e-051901276078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR SPECC1 ARHGAP5 ZNF106 SYNE2 ANKIB1

1.83e-05191127660c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR SPECC1 ARHGAP5 ZNF106 SYNE2 ANKIB1

1.83e-05191127609db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR SPECC1 ARHGAP5 ZNF106 SYNE2 ANKIB1

1.83e-051911276973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FAT4 MXRA5 TENM3 SRGAP3 NHS IFI44L

1.88e-051921276d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PDGFRA KIF26B ITGB5 NHS MSANTD4 TANC1

1.88e-051921276c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RELN MXRA5 PDGFRA KIF26B PLPPR3 TENM3

1.88e-051921276d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN KIF26B TENM3 TENM1 TANC1

1.94e-051931276d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VGF GALNT14 RELN KIF26B TENM3 TANC1

1.94e-0519312762c15186d15545804cc262da9137ab825609d4b2c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN KIF26B TENM3 TENM1 TANC1

1.94e-051931276010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

CLOCK BIRC6 GANAB PRKDC CRYBG3 CEP97

1.94e-051931276abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN KIF26B TENM3 TENM1 TANC1

1.94e-0519312762189da4b727e25e62669d7b9257f06493be21a27
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 ABCA13 VCAN SYNE2 NFAT5 MLPH

1.94e-0519312760f2167eef8203a5659c8c72e4e77646003d64797
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN KIF26B TENM3 TENM1 TANC1

1.94e-0519312763ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

MXRA5 PDGFRA NHSL2 KIF26B TENM3 VCAN

1.99e-05194127603a269f75a481ea54aea8e6444605db8d6df493d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN KIF26B ITGB5 TENM3 TENM1 TANC1

1.99e-05194127683863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 KIF26B TENM3 TENM1 NHS TANC1

1.99e-051941276e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRA SPECC1 ATP10D TENM3 LPIN2 TANC1

1.99e-05194127690efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

LRRC37A2 LAMA5 NCKAP5 PLEKHG4B ARHGAP5 TANC1

1.99e-05194127688db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRA SPECC1 ATP10D TENM3 LPIN2 TANC1

1.99e-051941276df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 ABCA13 ARSL KCNB1 SYNE2 NFAT5

1.99e-0519412768ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

LRRC37A2 LAMA5 NCKAP5 PLEKHG4B ARHGAP5 TANC1

1.99e-051941276a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 PDGFRA ITGB5 ADGRG4 IGSF10 VCAN

2.05e-051951276f54bc4454270ff06e85596f98199372b50d0179f
ToppCellASK428-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

IL16 MXRA5 PDGFRA IFI16 F5 CCNYL1

2.05e-051951276c750602c765a51075ba6ede78e3ba80b62374481
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IFI16 ITGB5 IFNGR1 ARHGAP5 SYNE2 CRYBG3

2.17e-05197127666339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

MXRA5 UGT1A6 LAMA5 SRGAP3 SYNE2 NHS

2.17e-05197127624360b660000bdfb999d58fbf4e29585a97e1785
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA13 KIF26B CHAF1A MUC16 SRGAP3 NHS

2.24e-05198127628ada093cec552262731194a04a4b9ff93186c3b
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL16 PDGFRA NHSL2 KIF26B TENM3 VCAN

2.24e-0519812763ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA13 KIF26B MUC16 PLEKHG4B SRGAP3 NHS

2.24e-051981276af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellmild-CD4+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TPR DGKA ARHGAP5 SYNE2 LPIN2 IFI44L

2.30e-0519912763e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

TPR SPECC1 INO80D ZNF106 SYNE2 LPIN2

2.30e-051991276c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

FAT4 KIAA1549 WAC GANAB WIZ VCAN

2.30e-051991276358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN KIF26B ITGB5 TENM3 TENM1 TANC1

2.37e-052001276a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT4 NCKAP5 IFI16 BIRC6 BMPR2 SYNE2

2.37e-052001276dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

MARK1 NCKAP5 PLEKHH3 AFAP1L2 SYNE2 TANC1

2.37e-0520012760c648941447c738caf62f2d71e296d6cca492c8b
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ABCA13 LAMA5 PLEKHH3 ARHGAP5 SRGAP3 SYNE2

2.37e-05200127697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN KIF26B ITGB5 TENM3 TENM1 TANC1

2.37e-05200127633b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MARK1 NCKAP5 PLEKHH3 AFAP1L2 SYNE2 TANC1

2.37e-052001276522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 IL16 PDGFRA NHSL2 VCAN TENM1

2.37e-052001276b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN KIF26B ITGB5 TENM3 TENM1 TANC1

2.37e-052001276347a510755374c6a66acee326565dfc447993f18
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MXRA5 PDGFRA NCKAP5 VCAN MYO3B SYNE2

2.37e-0520012763dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 IL16 PDGFRA NHSL2 ADGRG4 VCAN

2.37e-0520012763dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MARK1 NCKAP5 PLEKHH3 AFAP1L2 SYNE2 TANC1

2.37e-05200127694f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN KIF26B ITGB5 TENM3 TENM1 TANC1

2.37e-0520012769719fabddc34051949468a7520289e3c750de4f8
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MXRA5 PDGFRA NCKAP5 VCAN MYO3B SYNE2

2.37e-052001276ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 IL16 PDGFRA NHSL2 VCAN TENM1

2.37e-0520012760c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellNeuronal-Inhibitory-iB|Neuronal / cells hierarchy compared to all cells using T-Statistic

KIF26B AKNA TENM3 TENM1 NHS TANC1

2.37e-05200127645ddc5ef2caa87ada88327b63ba9b150a6bb3aa5
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 IL16 MXRA5 VCAN MYO3B TENM1

2.37e-05200127658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B PLEKHG4B SRGAP3 MYO3B MLPH

4.59e-05137127548c21e6938a46e3cd74ac10b8ace0a4751741af7
ToppCellremission-multiplets|World / disease stage, cell group and cell class

ABCA13 DGKA IGSF10 KCNB1 KIAA2012

5.45e-051421275286d01b4f95e9c0b38b91958f925f3797dffd596
Drug2,4,6-triphenyl-1-hexene

CYP1A1 CYP1A2 UGT1A6

1.64e-0651263ctd:C533342
Drug1,7-phenanthroline

CYP1A1 CYP1A2 UGT1A6

9.08e-0681263ctd:C053486
DrugAtovaquone [95233-18-4]; Up 200; 11uM; MCF7; HT_HG-U133A

CYP1A1 MAGEA8 IL16 MXRA5 ATP10B F5 KIDINS220 VCAN

1.28e-0519412684786_UP
DrugPilocarpine nitrate [148-72-1]; Down 200; 14.8uM; HL60; HT_HG-U133A

TESK1 INO80D SBNO2 BMPR2 KIDINS220 WIZ PCIF1 HERC6

1.38e-0519612682438_DN
DrugBaclofen (R,S) [1134-47-0]; Up 200; 18.8uM; PC3; HG-U133A

DGKA IFI16 INO80D SBNO2 WIZ TTLL4 LPIN2 MTRR

1.38e-0519612681952_UP
DrugSpectinomycin dihydrochloride [21736-83-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A

GALNT14 TPR WAC IFNGR1 BMPR2 SYNE2 TMPO MTRR

1.48e-0519812684773_DN
DrugFlurandrenolide [1524-88-5]; Down 200; 9.2uM; HL60; HT_HG-U133A

IFI16 F5 INO80D PCIF1 MTRR PRR14L HERC6 CEP97

1.48e-0519812682184_DN
Drugtamoxifen citrate; Up 200; 1uM; MCF7; HG-U133A

CYP1A1 F5 CALHM2 IFNGR1 SYNE2 PRR14L MTO1 NFAT5

1.54e-051991268143_UP
DrugPiribedil hydrochloride [78213-63-5]; Down 200; 12uM; PC3; HT_HG-U133A

GAK MAPK8IP3 IFNGR1 ARHGAP5 ALMS1 TTLL4 LPIN2 CABIN1

1.60e-0520012686333_DN
DrugKetotifen fumarate [34580-14-8]; Down 200; 9.4uM; PC3; HT_HG-U133A

CYP1A2 FAT4 ZNF318 SBNO2 VCAN LPIN2 TMPO PRR14L

1.60e-0520012685842_DN
Drug2-methoxy-4-aminoazobenzene

CYP1A1 CYP1A2

3.04e-0521262ctd:C053767
Drug3,4,3',4'-tetrachloroazoxybenzene

CYP1A1 CYP1A2

3.04e-0521262ctd:C013280
Drugcloflucarban

CYP1A1 CYP1A2

3.04e-0521262ctd:C005055
Drugmusk xylene

CYP1A1 CYP1A2

3.04e-0521262ctd:C031447
Drugsesamex

CYP1A1 CYP1A2

3.04e-0521262ctd:C100180
DrugCanthaxanthin

CYP1A1 CYP1A2

3.04e-0521262ctd:D016644
DrugPigment Yellow 74

CYP1A1 CYP1A2

3.04e-0521262CID000022829
Drugpyridoxal isonicotinoyl hydrazone

CYP1A1 CYP1A2

3.04e-0521262ctd:C021079
Drugnitroaniline

CYP1A1 CYP1A2

3.04e-0521262ctd:C008625
Drug7H-dibenzo(c,g)carbazole

CYP1A1 CYP1A2

3.04e-0521262ctd:C013478
Drug2,7-dinitrofluorene

CYP1A1 CYP1A2

3.04e-0521262ctd:C085049
Drugbeta-apo-8'-carotenal

CYP1A1 CYP1A2

3.04e-0521262ctd:C110652
Drugpropachlor

CYP1A1 CYP1A2

3.04e-0521262ctd:C011088
Drugallocryptopine

CYP1A1 CYP1A2

3.04e-0521262ctd:C109505
Drug2,7-FAA

CYP1A1 CYP1A2

3.04e-0521262CID000009352
Drugprotopine

CYP1A1 CYP1A2

3.04e-0521262ctd:C009093
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

GALNT14 SETD1B LAMA5 CALHM2 SBNO2 WIZ TMPO

6.81e-0518112676951_DN
Drugerucin

CYP1A1 CYP1A2 UGT1A6

7.17e-05151263ctd:C073539
DrugResveratrol [501-36-0]; Down 200; 17.6uM; PC3; HT_HG-U133A

BMPR2 VCAN TMPO PRR14L IFI44L CABIN1 NFAT5

8.93e-0518912675084_DN
Drug2,3-diaminotoluene

CYP1A1 CYP1A2

9.08e-0531262ctd:C100420
Drug2-amino-1-methyl-6-phenyl-1H-imidazo(4,5-b)pyridine

CYP1A1 CYP1A2

9.08e-0531262ctd:C522525
Drug2-amino-1,7-dimethylimidazo(4,5-g)quinoxaline

CYP1A1 CYP1A2

9.08e-0531262ctd:C519626
Drugscutellarein

CYP1A1 CYP1A2

9.08e-0531262ctd:C458179
Druggenkwanin

CYP1A1 CYP1A2

9.08e-0531262ctd:C014568
Drug1-methoxyrutaecarpine

CYP1A1 CYP1A2

9.08e-0531262CID005319487
DrugSuppressor Factors, Immunologic

CYP1A1 CYP1A2

9.08e-0531262ctd:D013491
Drugalyssin

CYP1A1 CYP1A2

9.08e-0531262ctd:C524316
Drug2-oxohexyl isothiocyanate

CYP1A1 CYP1A2

9.08e-0531262ctd:C524315
DrugTrichloroepoxypropane

CYP1A1 CYP1A2

9.08e-0531262ctd:D014239
Drug3-aminofluorene

CYP1A1 CYP1A2

9.08e-0531262CID000022818
Drug1-aminofluorene

CYP1A1 CYP1A2

9.08e-0531262CID000022817
Drug2,2',4,6'-tetramethoxystilbene

CYP1A1 CYP1A2

9.08e-0531262ctd:C541980
Drug6-nitrobenzo(a)pyrene

CYP1A1 CYP1A2

9.08e-0531262ctd:C034699
Drugchlortoluron

CYP1A1 CYP1A2

9.08e-0531262ctd:C007033
DrugAminoquinolines

CYP1A1 CYP1A2

9.08e-0531262ctd:D000634
Drug7-(deoxyadenosin-N(6)--yl)aristolactam II

CYP1A1 CYP1A2

9.08e-0531262ctd:C405699
Drug1,2,3,7,8-pentachlorodibenzofuran

CYP1A1 CYP1A2

9.08e-0531262ctd:C057584
Drug7-nitrobenzanthracene

CYP1A1 CYP1A2

9.08e-0531262ctd:C038954
Drug1,2-dichloroethylene

CYP1A1 CYP1A2

9.08e-0531262ctd:C035384
DrugSanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A

VGF ZNF318 ZNF106 ALMS1 SYNE2 LPIN2 PRKDC

9.54e-0519112674168_DN
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A

VGF TPR CYP1A1 CYP1A2 CALHM2 PCIF1 PRR14L

1.02e-0419312671652_UP
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A

TPR CYP1A1 NDOR1 BMPR2 KIDINS220 PRR14L NFAT5

1.05e-0419412674134_DN
DrugAC1LC42M

A1BG CYP1A1 CYP1A2

1.06e-04171263CID000547456
DrugIsradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A

VGF CYP1A1 ATP10D MAPK8IP3 WIZ ALMS1 CEP97

1.09e-0419512675447_DN
DrugHarpagoside [19210-12-9]; Down 200; 8uM; HL60; HT_HG-U133A

PLPPR3 TESK1 SBNO2 BMPR2 WIZ ALMS1 TTLL4

1.12e-0419612672935_DN
DrugMeclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; HL60; HT_HG-U133A

TESK1 INO80D SBNO2 MAPK8IP3 BMPR2 KIDINS220 HERC6

1.12e-0419612672424_DN
DrugDropropizine (R,S) [17692-31-8]; Up 200; 17uM; PC3; HT_HG-U133A

THEMIS2 GALNT14 CYP1A1 IL16 INO80D SBNO2 ALMS1

1.16e-0419712675106_UP
DrugReserpinic acid hydrochloride; Down 200; 9.2uM; HL60; HT_HG-U133A

PLPPR3 TESK1 F5 INO80D SBNO2 WIZ PCIF1

1.16e-0419712672903_DN
DrugXylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; PC3; HT_HG-U133A

MARK1 SBNO2 MAPK8IP3 HPS6 PRR14L IFI44L CABIN1

1.19e-0419812672107_UP
DrugFlurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A

VGF CYP1A1 ZNF318 TESK1 INO80D MAPK8IP3 CABIN1

1.19e-0419812676472_DN
DrugNaphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; PC3; HT_HG-U133A

GALNT14 CALHM2 VCAN IFI44L CABIN1 MUC6 CDH10

1.19e-0419812676604_UP
DrugAmiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; HL60; HG-U133A

SETD1B TESK1 MAPK8IP3 ALMS1 TMPO MTO1 NFAT5

1.19e-0419812671970_DN
DrugNisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A

RELN ZNF318 KCNB1 SRGAP3 VCAN TTLL4 MUC6

1.19e-0419812676496_UP
DrugEstrone [53-16-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A

VGF CYP1A1 INO80D MAPK8IP3 ALMS1 HPS6 CABIN1

1.23e-0419912676448_DN
DrugEdrophonium chloride [116-38-1]; Down 200; 19.8uM; PC3; HT_HG-U133A

VGF GALNT14 CHAF1A KIDINS220 TENM3 TENM1 CABIN1

1.23e-0419912676655_DN
DrugGabapentin [60142-96-3]; Down 200; 23.4uM; HL60; HT_HG-U133A

CASS4 CYP1A2 SETD1B F5 KIDINS220 WIZ VCAN

1.23e-0419912672731_DN
DrugBenzene

CYP1A1 CYP1A2 IL16 UGT1A6 AKNA TESK1 F5 ITGB5 IFNGR1 KIDINS220 VCAN HPS6 IFI44L PRKDC NFAT5

1.25e-0489212615ctd:D001554
DrugAscorbic acid [50-81-7]; Down 200; 22.4uM; HL60; HG-U133A

CYP1A2 SETD1B ANKRD27 CALHM2 MAPK8IP3 CABIN1 MLPH

1.27e-0420012671610_DN
Drugrutecarpine

CYP1A1 CYP1A2 BMPR2

1.27e-04181263ctd:C028632
Drugtectochrysin

CYP1A1 CYP1A2 UGT1A6

1.76e-04201263CID005281954
Drug1-chloropyrene

CYP1A1 CYP1A2

1.81e-0441262ctd:C040345
Drugpurpurin

CYP1A1 CYP1A2

1.81e-0441262ctd:C511975
Drug2-nitrofluoranthene

CYP1A1 CYP1A2

1.81e-0441262ctd:C049030
Drug7-methoxyresorufin

CYP1A1 CYP1A2

1.81e-0441262ctd:C076580
Drug2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester

CYP1A1 CYP1A2

1.81e-0441262ctd:C520611
Drugmusk ketone

CYP1A1 CYP1A2

1.81e-0441262ctd:C031448
Drug3,6-dinitrobenzopyrene

CYP1A1 CYP1A2

1.81e-0441262ctd:C068923
DrugPY74

CYP1A1 CYP1A2

1.81e-0441262CID000017893
DrugN-methyl-7H-dibenzo(c,g)carbazole

CYP1A1 CYP1A2

1.81e-0441262ctd:C041150
Drugterbutryne

CYP1A1 CYP1A2

1.81e-0441262ctd:C010347
Drugthiacloprid

CYP1A1 CYP1A2

1.81e-0441262ctd:C417209
Drug5,5'-bis-trifluoromethyl-2,2'-dichlorobiphenyl

CYP1A1 CYP1A2

1.81e-0441262CID000057528
Drug1,2,3,5,6,7-hexachloronaphthalene

CYP1A1 CYP1A2

1.81e-0441262ctd:C575652
DrugKC 500

CYP1A1 CYP1A2

1.81e-0441262ctd:C477388
Drug3-((2,4-dimethylpyrrol-5-yl)methylidenyl)-2-indolinone

CYP1A1 CYP1A2

1.81e-0441262ctd:C549241
Drug3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide

CYP1A1 CYP1A2

1.81e-0441262ctd:C520945
Drugtasquinimod

CYP1A1 CYP1A2

1.81e-0441262ctd:C516109
Drug3-hydroxyrutaecarpine

CYP1A1 CYP1A2

1.81e-0441262CID000637395
Drugsinensetin

CYP1A1 CYP1A2

1.81e-0441262ctd:C059295
Drugalpha-hederin

CYP1A1 CYP1A2

1.81e-0441262ctd:C010177
Drug4-aminofluorene

CYP1A1 CYP1A2

1.81e-0441262CID000023488
DrugQuinolinium Compounds

CYP1A1 CYP1A2

1.81e-0441262ctd:D011806
Drugolivacine

CYP1A1 CYP1A2

1.81e-0441262ctd:C011521
Drugprochloraz

CYP1A1 MUC12 IFI16 HPS6 MLPH EIF2AK3

2.27e-041551266CID000073665
DrugTETs

A1BG BIRC6 TET1

2.36e-04221263CID000064148
DrugQuinine

CYP1A1 CYP1A2 SLC47A2

2.36e-04221263ctd:D011803
DrugMPB-PE

NHS FCAMR

3.01e-0451262CID000124842
Drugfluorene

CYP1A1 CYP1A2

3.01e-0451262ctd:C041509
Drug6-hydroxychrysene

CYP1A1 UGT1A6

3.01e-0451262ctd:C087203
Drug1,2,3,4,6,7-hexachlorinated naphthalene

CYP1A1 CYP1A2

3.01e-0451262ctd:C412791
Diseaseplasma clozapine measurement

CYP1A1 CYP1A2 UGT1A6

3.62e-0681203EFO_0600038
Diseaseplasma N-desmethylclozapine measurement

CYP1A1 CYP1A2 UGT1A6

1.06e-05111203EFO_0600039
DiseaseVan Maldergem Wetzburger Verloes syndrome

FAT4 DCHS1

1.64e-0521202C1832390
Disease5-hydroxy-2-methylpyridine sulfate measurement

CYP1A1 CYP1A2

1.64e-0521202EFO_0801051
DiseaseVan Maldergem syndrome

FAT4 DCHS1

1.64e-0521202cv:C1832390
Disease1-stearoylglycerol 1-monostearin measurement

KIAA1549 SYNE2

1.64e-0521202EFO_0021111
Diseaseserum clozapine measurement

CYP1A1 CYP1A2

1.64e-0521202EFO_0600041
Diseasehypereosinophilic syndrome (is_implicated_in)

PDGFRA F5

1.64e-0521202DOID:999 (is_implicated_in)
DiseasePeriventricular gray matter heterotopia

FAT4 DCHS1

1.64e-0521202C1849173
Diseaseprogressive familial intrahepatic cholestasis (implicated_via_orthology)

ATP10B ATP10D

4.91e-0531202DOID:0070221 (implicated_via_orthology)
Diseaseglycosyl ceramide (d16:1/24:1, d18:1/22:1) measurement

ATP10D SYNE2

4.91e-0531202EFO_0800530
DiseaseHeterotopia, Periventricular, Autosomal Recessive

FAT4 DCHS1

4.91e-0531202C1842563
Diseaseheart septal defect (is_implicated_in)

BMPR2 MTRR

9.79e-0541202DOID:1681 (is_implicated_in)
DiseaseX-21286 measurement

CYP1A1 CYP1A2

9.79e-0541202EFO_0800804
DiseaseMalignant neoplasm of breast

THEMIS2 CYP1A1 LRRC37A2 ZNF318 TESK1 SGK3 PPP1R3A BMPR2 SRGAP3 SYNE2 TENM1 SLC39A6 NHS CDH10

1.22e-04107412014C0006142
Diseaseporphyria cutanea tarda (is_implicated_in)

CYP1A1 CYP1A2

2.43e-0461202DOID:3132 (is_implicated_in)
Diseasecystatin C measurement

CYP1A1 CYP1A2 NBAS BMPR2 ALMS1 TANC1 NFAT5 KIAA2012

2.47e-044021208EFO_0004617
DiseasePilomyxoid astrocytoma

KIAA1549 SRGAP3

3.40e-0471202C1519086
Diseaseglycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement

ATP10D SYNE2

3.40e-0471202EFO_0800551
Disease2-aminooctanoate measurement

LDHD ALMS1

4.52e-0481202EFO_0800349
Diseaseadvanced glycation end-product measurement

CYP1A1 CYP1A2

5.80e-0491202EFO_0007819
Disease4-vinylphenol sulfate measurement

SGK3 ARSL

7.23e-04101202EFO_0021149
Diseasetheophylline measurement

CYP1A1 CYP1A2

7.23e-04101202EFO_0021180
Diseasesweet beverage consumption measurement

CYP1A1 CYP1A2

7.23e-04101202EFO_0010090
Disease2-ketocaprylate measurement

LDHD ALMS1

7.23e-04101202EFO_0800110
Disease1,7-dimethylurate measurement

CYP1A1 CYP1A2

7.23e-04101202EFO_0021512
DiseaseNephroblastoma

NBAS NHS

7.23e-04101202Orphanet_654
Diseaseage at onset, multiple sclerosis

RELN NCKAP5

7.23e-04101202EFO_0004847, MONDO_0005301
Disease1-methylxanthine measurement

CYP1A1 CYP1A2

8.81e-04111202EFO_0021174
Disease5-acetylamino-6-amino-3-methyluracil measurement

CYP1A1 CYP1A2

8.81e-04111202EFO_0800951
DiseaseMale sterility

CYP1A1 NSUN7 MTRR

9.93e-04481203C0917731
DiseaseMale infertility

CYP1A1 NSUN7 MTRR

9.93e-04481203C0021364
DiseaseSubfertility, Male

CYP1A1 NSUN7 MTRR

9.93e-04481203C0848676
Diseaseparaxanthine measurement

CYP1A1 CYP1A2

1.05e-03121202EFO_0021178
DiseaseN-acetyl-2-aminooctanoate measurement

LDHD ALMS1

1.05e-03121202EFO_0800567
DiseaseHepatomegaly

A1BG CYP1A1 CYP1A2

1.40e-03541203C0019209
Diseaselobe attachment

FAT4 PDGFRA TTLL4 MYO3B PRKDC

1.61e-032071205EFO_0007667
Disease1,3,7-trimethylurate measurement

CYP1A1 CYP1A2

1.66e-03151202EFO_0021172
Diseasecoffee consumption, cups of coffee per day measurement

CYP1A1 CYP1A2

1.90e-03161202EFO_0004330, EFO_0006782
Diseasetea consumption measurement

CYP1A1 CYP1A2 PLEKHH3 NFAT5

1.94e-031291204EFO_0010091
Diseaseblood lead measurement

KCNB1 SRGAP3 TANC1

2.49e-03661203EFO_0007040
Diseasecaffeine metabolite measurement

CYP1A1 CYP1A2

2.68e-03191202EFO_0007872
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

MADD ZNF106 SYNE2 PCIF1

2.88e-031441204EFO_0004611, EFO_0020943
DiseaseContact Dermatitis

CYP1A1 UGT1A6 PRDX6

3.07e-03711203C0011616
DiseaseContact hypersensitivity

CYP1A1 UGT1A6 PRDX6

3.07e-03711203C0162351
DiseaseLung Injury

CYP1A1 CYP1A2

3.27e-03211202C0273115
DiseaseChronic Lung Injury

CYP1A1 CYP1A2

3.27e-03211202C2350344
DiseaseSchizophrenia

A1BG CYP1A2 RELN ABCA13 CLOCK PRDX6 SBNO2 KCNB1 SRGAP3 TET1

3.29e-0388312010C0036341
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

RELN PPP1R3A MST1R TET1 NFAT5 KIAA2012

3.80e-033641206EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasebody fat percentage

RELN PPP1R3A MST1R SRGAP3 TET1 NFAT5 KIAA2012

3.88e-034881207EFO_0007800

Protein segments in the cluster

PeptideGeneStartEntry
SIHDLPLFTETSPTS

AAAS

511

Q9NRG9
LSRDPSETHILTPAS

ARSL

516

P51690
TLPFHVLRSLFSTTP

BIRC6

4211

Q9NR09
TSFAEESRPHALPSS

CASS4

261

Q9NQ75
STTPFPSQHRTEIEL

VCAN

641

P13611
NRSHISETPLDSESP

CRYBG3

616

Q68DQ2
HSPSRTPVLVGSDEF

EIF2AK3

436

Q9NZJ5
LTETPFHSLRLSTPV

ADGRG4

1106

Q8IZF6
SPISPHFTVTERQTF

ACRBP

151

Q8NEB7
HDLPQIPASRFTSTA

FAT4

2021

Q6V0I7
PLERSDFTGSHSEPS

ALMS1

2811

Q8TCU4
TTVDTTHLENVSPRP

AFAP1L2

756

Q8N4X5
FEHITAETPSRPLSS

SPECC1

331

Q5M775
SSIVPSFHSLPSLTE

ABCA13

751

Q86UQ4
VAPDHFASSLASRVP

BSX

36

Q3C1V8
PFSTDTLSSHPLSEA

ANKIB1

931

Q9P2G1
RTEASRTHPSPFLAL

C1orf147

26

Q96MC9
PEEDSVLSHSSLSSP

CHAF1A

276

Q13111
ALESNPSDHPRASTI

CCNYL1

76

Q8N7R7
PSDHPRASTIFLSKS

CCNYL1

81

Q8N7R7
HRESSQPPVAFSSSI

ATP10B

526

O94823
SEVPHSRQAAFSSPI

ATP10D

531

Q9P241
FVPFTIPHSTTRDTS

CYP1A1

381

P04798
FLPFTIPHSTTRDTT

CYP1A2

381

P05177
ALAFSRTHSPLLSTP

KIAA1549

351

Q9HCM3
RTHSPLLSTPLAFAS

KIAA1549

356

Q9HCM3
LVPRSSTSPDRIFFH

A1BG

251

P04217
PSVVTPFSRDDRGHT

ANKRD27

451

Q96NW4
RTTDPETPVTLHNSE

PDGFRA

151

P16234
FPHSEITTLRSRTPG

MUC16

5601

Q8WXI7
SPVTQRFPHSEETTT

MUC16

5891

Q8WXI7
SHSSPLRVTSLFTPV

MUC16

8876

Q8WXI7
TTIRATLPHTISSPF

MUC6

2206

Q6W4X9
HSPRLSEDPTFLAVA

DCHS1

1101

Q96JQ0
SHVVPEDPRFLSESS

KIDINS220

1281

Q9ULH0
RHPSSDSVAQTPELL

MADD

21

Q8WXG6
STSPDPAHLESLFRE

MAGEA8

96

P43361
TATLRPGPLTEHVFT

MAPK8IP3

911

Q9UPT6
IPEPTTETRHSTALE

LRRC37A2

756

A6NM11
CPERSHISDQSPLSS

TMPO

341

P42166
SESEHLPARDSPSLS

LSG1

281

Q9H089
SSDSAAPRTPHFDVI

MTO1

26

Q9Y2Z2
PEHSTFITSPSLKDR

IFI44L

301

Q53G44
RATVDPDFPIAHLSS

KIF26B

836

Q2KJY2
LSEHPLLSEPSSVSF

KIAA1109

2336

Q2LD37
SISPRTTNSFHLPDD

MTRR

521

Q9UBK8
RLFPSLSITTELTHP

KCNT1

891

Q5JUK3
VDPSSLTAREEHFPS

CALHM2

136

Q9HA72
PETFSERDHPTSITC

HERC6

971

Q8IVU3
DVDISTHSPSLPLAR

IL16

536

Q14005
STSEALRIDPVPNTH

DGKA

361

P23743
TVHLPVDASRDTLSP

KIAA2012

476

Q0VF49
SPEFVEPRVSCISSH

LAMA5

1196

O15230
VTSHETSDFFPRPLR

MIER3

131

Q7Z3K6
SPASSFHVLRSLPLS

ITGB5

81

P18084
RLAILSNFPETTSPH

NBAS

756

A2RRP1
FSSTEPTVHTRPDNL

NFAT5

846

O94916
PRAFSIASSLLTHPS

NDOR1

381

Q9UHB4
LDTFSSAPVPQHERS

RELN

2671

P78509
AIPTRAITADVSHSP

PPP1R3A

571

Q16821
PPTSIIITFHNEARS

GALNT14

111

Q96FL9
PPSSSADASRFLHTL

GAK

781

O14976
TFPEDESSSRTLAPV

FCAMR

441

Q8WWV6
FPASPTREAHRESSV

FBF1

356

Q8TES7
IIRHSTIPPFLSSSA

IGSF10

1456

Q6WRI0
TDFPEATRFSHSPLT

KCNB1

596

Q14721
RSEKNHFESSPLPTS

KCNB1

791

Q14721
ATTSFPLHSPGLLET

CABIN1

346

Q9Y6J0
SHFERLLESSPEPLS

PCIF1

566

Q9H4Z3
SREAPNPIHLTVDTS

EIF3F

191

O00303
PDSISSPIRFSLDRH

CDH10

411

Q9Y6N8
TRASLIPEHSSPVQD

CEP97

321

Q8IW35
TATTLRLHPAPEATV

LDHD

256

Q86WU2
TTPLSPPHSFNRDET

BMPR2

136

Q13873
HSEVNPSVELSPARS

AKNA

186

Q7Z591
EASTTFPESHLRTPQ

IFI16

416

Q16666
AHSISTATPDRTRFP

MARK1

591

Q9P0L2
VEASHIRSPSTPELS

INO80D

581

Q53TQ3
PRFHDTSSPLLISGT

EPS15

101

P42566
LRGTPETPTSHFAVS

FCRLB

401

Q6BAA4
LTEPTLALSAESHRP

C1orf127

626

Q8N9H9
LTPEELRHSSTFRAP

HPS6

421

Q86YV9
ESCPSVSIPSSDEHR

SGK3

11

Q96BR1
LAPVPTHSTVSELSR

DUSP5

361

Q16690
VPGSHLTPIERESSS

IFNGR1

366

P15260
SLHLSSVPEARDSPQ

MLPH

211

Q9BV36
TTESSRTFPEHCAPA

PRR14L

1731

Q5THK1
SDVSEEPVPHRTITS

RUSC1

301

Q9BVN2
PSTTPSPDSELHRVF

SPATA48

386

A4D263
SLSRPGETEPIHSVS

PLEKHH3

691

Q7Z736
TETVRSQTHSLPAPE

VGF

116

O15240
PEEAHALSAPTSRLS

SLC47A2

556

Q86VL8
SVLDRLPQPAESSTH

SYNE2

5451

Q8WXH0
ISPDLSHTTLSPDLS

F5

1231

P12259
RPADSAIVHSTSDPI

NCKAP5

1781

O14513
TTSDIRPSHSVPEGV

NHSL2

311

Q5HYW2
HFLTFNSTRSPSPTE

NHS

281

Q6T4R5
CVHFLTATPDPSRSV

SCRN2

301

Q96FV2
SCIFPSTTIPDHLSS

NSUN7

111

Q8NE18
PESRLSFQHDPETSV

GANAB

911

Q14697
LFSHPRDFTPVCTTE

PRDX6

36

P30041
TSDPTQDLHFTPLLS

TANC1

451

Q9C0D5
STHVIPPEVSFDSRR

TENM1

871

Q9UKZ4
HPDRVVETSTLSSVP

SBNO2

216

Q9Y2G9
FPSTHDPRTVTLDFR

SETD1B

1561

Q9UPS6
DYRLPRAETHSSSTP

WAC

231

Q9BTA9
SSLEARSPSDLHISP

WIZ

1121

O95785
ESTHQSEDVFLPSPR

ARHGAP5

956

Q13017
SEVHPSLERATPQTS

SEBOX

156

Q9HB31
PHIDEFFTLNSTPSR

MSANTD4

181

Q8NCY6
NPSRPSSSELVELHV

SPATA1

26

Q5VX52
SEGTHFLETIETPRP

SLC39A6

196

Q13433
SHETPLPESALTLRN

TET1

1341

Q8NFU7
LERFDHSPTPSASSR

CLOCK

421

O15516
TPSSFSVELPSNRHI

C12orf40

151

Q86WS4
VLDEASHQRTPAPSS

SPEM2

406

Q0P670
SSEPASPLHTIVIRD

SRGAP3

1006

O43295
VTFSHTLPRASAPSL

PLPPR3

371

Q6T4P5
STPTLVVPHRTDGFA

TPR

2136

P12270
AAPFKRPHSTISDSS

PLEKHG4B

1181

Q96PX9
DTSHPTDPLTSFLGL

THEMIS2

461

Q5TEJ8
LSTFFRSSPEDSPII

TENM3

971

Q9P273
LEPSTRAPFTEITQH

TESK1

296

Q15569
PLVDHTSPSSDSLLF

PRKDC

2666

P78527
CSLEHTFSRSPDPVS

UGT1A6

176

P19224
EVNISPSLHSSSPLD

TTLL4

906

Q14679
HSELERSFLSEPSSP

VIRMA

1566

Q69YN4
PASVTDDPSALHTRL

MST1R

266

Q04912
PVDFCTTRVSPAHRS

ZNF318

2021

Q5VUA4
ARLSLPESTESFHEP

ZNF106

1246

Q9H2Y7
DHFRPAILTSRESPT

ZNF181

136

Q2M3W8
TRPSTSHFSVLSFTP

SIGLEC16

191

A6NMB1
LSPDRSAEVSNSIHP

INSYN2B

221

A6NMK8
TFHSSPGDTETTLLP

MUC12

1526

Q9UKN1
SVRGEEPTTFHSRPA

MUC12

2406

Q9UKN1
VRGEEPTTFHSRPAS

MUC12

2881

Q9UKN1
TFHSSPGDTETTLLP

MUC12

4166

Q9UKN1
TPSENTHFRVIPSED

LPIN2

291

Q92539
PSEVHCTFRSLASVP

MXRA5

36

Q9NR99
ARITVASSSLPPHFS

MYO3B

891

Q8WXR4