Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF140 ZNF354A ZNF493 ZNF670 ZNF273 ZNF268 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 EOMES ZNF14 ZNF836 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 GRHL3 ZNF417 ZNF345 ZNF239

2.64e-05124417326GO:0000978
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF140 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 EOMES ZNF14 ZNF836 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 GRHL3 ZNF417 ZNF345 ZNF239

3.21e-05141217328GO:0000981
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF140 ZNF354A ZNF493 ZNF670 ZNF273 ZNF268 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 EOMES ZNF14 ZNF836 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 GRHL3 ZNF417 ZNF345 ZNF239

3.80e-05127117326GO:0000987
GeneOntologyMolecularFunctionATPase-coupled ion transmembrane transporter activity

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

5.05e-05241734GO:0042625
GeneOntologyMolecularFunctionATPase activity, coupled to transmembrane movement of ions, rotational mechanism

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

5.05e-05241734GO:0044769
GeneOntologyMolecularFunctionproton-transporting ATPase activity, rotational mechanism

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

5.05e-05241734GO:0046961
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF140 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 EOMES ZNF14 ZNF836 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 GRHL3 ZNF417 ZNF345 ZNF239

5.72e-05145917328GO:0000977
GeneOntologyMolecularFunctionphosphatidylserine transfer activity

OSBPL5 OSBPL8

7.46e-0521732GO:0140343
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP6V1A ATP6V1B1 ATP6V1B2 ATP7A ATP6V1G1

2.00e-04621735GO:0019829
GeneOntologyMolecularFunctionlow-affinity IgG receptor activity

FCGR3A FCGR3B

4.43e-0441732GO:0019772
GeneOntologyMolecularFunctionhistone H3K9me/H3K9me2 demethylase activity

KDM3A KDM3B

7.34e-0451732GO:0140683
GeneOntologyMolecularFunctionIgE receptor activity

FCGR3A FCGR3B

1.09e-0361732GO:0019767
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF493 ZNF268 ZNF208 E4F1 ZNF225 RREB1 ZNF850 BNC1 ZNF14 ZNF836 ZNF91 GRHL3 ZNF345

1.35e-0356617313GO:0001216
GeneOntologyMolecularFunctionIgE binding

FCGR3A FCGR3B

1.52e-0371732GO:0019863
GeneOntologyMolecularFunctionIgG receptor activity

FCGR3A FCGR3B

1.52e-0371732GO:0019770
GeneOntologyCellularComponentextrinsic component of synaptic vesicle membrane

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1 ATM

1.75e-06251745GO:0098850
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase, V1 domain

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

2.18e-06121744GO:0000221
GeneOntologyCellularComponentproton-transporting V-type ATPase, V1 domain

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

2.18e-06121744GO:0033180
GeneOntologyCellularComponentproton-transporting V-type ATPase complex

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1 ATP6AP1L

3.81e-06291745GO:0033176
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex, catalytic domain

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

1.63e-05191744GO:0033178
GeneOntologyCellularComponentextrinsic component of organelle membrane

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1 ATM

2.81e-05431745GO:0031312
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1 ATP6AP1L

5.35e-05491745GO:0090533
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase complex

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

6.01e-05261744GO:0016471
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1 ATP6AP1L

7.83e-05531745GO:0016469
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1 ATP6AP1L

9.37e-05551745GO:0098533
GeneOntologyCellularComponentFc-gamma receptor III complex

FCGR3A FCGR3B

4.09e-0441742GO:0033001
GeneOntologyCellularComponentpore complex

CD34 C6 VDAC3

1.28e-03261743GO:0046930
GeneOntologyCellularComponentdendritic branch

MAP2 GRIN2B

1.41e-0371742GO:0044307
Domainzf-C2H2_6

ZNF140 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 ZNF14 ZNF836 ZNF587 ZNF561 ZNF84 ZNF91 ZNF417 ZNF541 ZNF345

9.73e-1331416921PF13912
DomainZINC_FINGER_C2H2_2

ZNF140 ZNF609 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 BNC1 ZNF14 ZNF836 ZNF469 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 ZNF839 ZNF417 ZNF541 ZNF345 ZNF239

2.61e-1277516931PS50157
DomainZINC_FINGER_C2H2_1

ZNF140 ZNF609 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 BNC1 ZNF14 ZNF836 ZNF469 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 ZNF839 ZNF417 ZNF541 ZNF345 ZNF239

2.79e-1277716931PS00028
Domainzf-C2H2

ZNF140 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 BNC1 ZNF14 ZNF836 ZNF469 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 ZNF417 ZNF541 ZNF345 ZNF239

4.88e-1269316929PF00096
DomainZnf_C2H2-like

ZNF140 ZNF609 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 BNC1 ZNF14 ZNF836 ZNF469 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 ZNF839 ZNF417 ZNF541 ZNF345 ZNF239

5.19e-1279616931IPR015880
DomainZnf_C2H2

ZNF140 ZNF609 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 BNC1 ZNF14 ZNF836 ZNF469 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 ZNF839 ZNF417 ZNF541 ZNF345 ZNF239

6.92e-1280516931IPR007087
DomainZnF_C2H2

ZNF140 ZNF609 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 BNC1 ZNF14 ZNF836 ZNF469 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 ZNF839 ZNF417 ZNF541 ZNF345 ZNF239

7.62e-1280816931SM00355
DomainZnf_C2H2/integrase_DNA-bd

ZNF140 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 ZNF14 ZNF836 ZNF469 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 ZNF417 ZNF541 ZNF345 ZNF239

2.81e-1169416928IPR013087
Domain-

ZNF140 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 ZNF14 ZNF836 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 ZNF417 ZNF541 ZNF345 ZNF239

9.20e-11679169273.30.160.60
DomainKRAB

ZNF140 ZNF354A ZNF266 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 ZNF225 ZNF354B ZNF850 ZNF14 ZNF836 ZNF23 ZNF587 ZNF561 ZNF84 ZNF91 ZNF417

6.54e-1035816919PS50805
DomainKRAB

ZNF140 ZNF354A ZNF266 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 ZNF225 ZNF354B ZNF850 ZNF14 ZNF836 ZNF23 ZNF587 ZNF561 ZNF84 ZNF91 ZNF417

1.08e-0936916919SM00349
DomainKRAB

ZNF140 ZNF354A ZNF266 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 ZNF225 ZNF354B ZNF850 ZNF14 ZNF836 ZNF23 ZNF587 ZNF561 ZNF84 ZNF91 ZNF417

1.13e-0937016919IPR001909
DomainKRAB

ZNF140 ZNF354A ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 ZNF225 ZNF354B ZNF850 ZNF14 ZNF836 ZNF587 ZNF561 ZNF84 ZNF91 ZNF417

2.83e-0835816917PF01352
DomainATP_synth_asu_C

ATP6V1A ATP6V1B1 ATP6V1B2

7.18e-0651693IPR000793
DomainATP-synt_ab_N

ATP6V1A ATP6V1B1 ATP6V1B2

7.18e-0651693PF02874
DomainATPase_F1/V1/A1_a/bsu_N

ATP6V1A ATP6V1B1 ATP6V1B2

7.18e-0651693IPR004100
DomainATPase_a/bsu_AS

ATP6V1A ATP6V1B1 ATP6V1B2

7.18e-0651693IPR020003
DomainATP-synt_ab_C

ATP6V1A ATP6V1B1 ATP6V1B2

7.18e-0651693PF00306
DomainATP-synt_ab

ATP6V1A ATP6V1B1 ATP6V1B2

7.18e-0651693PF00006
DomainATPASE_ALPHA_BETA

ATP6V1A ATP6V1B1 ATP6V1B2

7.18e-0651693PS00152
DomainATPase_F1/V1/A1_a/bsu_nucl-bd

ATP6V1A ATP6V1B1 ATP6V1B2

1.43e-0561693IPR000194
DomainV-ATPase_su_B/beta

ATP6V1B1 ATP6V1B2

8.14e-0521692IPR022879
DomainATPase_V1-cplx_bsu

ATP6V1B1 ATP6V1B2

8.14e-0521692IPR005723
DomainPentaxin-related

ADGRG4 ADGRG6 ADGRD2

1.14e-04111693IPR001759
DomainPentaxin

ADGRG4 ADGRG6 ADGRD2

1.14e-04111693PF00354
DomainDUF4592

KIAA1210 CRACDL

2.43e-0431692IPR028030
DomainDUF4592

KIAA1210 CRACDL

2.43e-0431692PF15262
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF140 ZNF354A ZNF493 ZNF670 ZNF273 ZNF208 ZNF354B ZNF587 ZNF561 ZNF84 ZNF91 ZNF417

1.75e-101811771237372979
Pubmed

Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.

ZNF266 ZNF273 ZNF268 ZNF23 ZNF345

6.14e-082117757865130
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ATP6V1A SHROOM3 RPGRIP1L ATP7A ZFYVE27 AFF2 KDM3B RNF213 PTBP1 ARL15 CEP350 EEF2 ARFRP1 DST DDX50 ADAMTS16 PTGES3 PCNA

1.07e-077771771835844135
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF493 ZNF670 ZNF208 ZNF850 ZNF836 ZNF91

1.86e-074917769630514
Pubmed

V-ATPase expression in the mouse olfactory epithelium.

ATP6V1A ATP6V1B1 ATP6V1B2

5.16e-074177318667600
Pubmed

Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

1.47e-0617177433065002
Pubmed

The Presynaptic v-ATPase Reversibly Disassembles and Thereby Modulates Exocytosis but Is Not Part of the Fusion Machinery.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

1.47e-0617177428793259
Pubmed

Animal plasma membrane energization by proton-motive V-ATPases.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

1.88e-0618177410440860
Pubmed

The vacuolar H+-ATPase: a universal proton pump of eukaryotes.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

1.88e-061817749210392
Pubmed

Vacuolar and plasma membrane proton-adenosinetriphosphatases.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

1.88e-0618177410221984
Pubmed

Introduction: V-ATPases 1992-1998.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

1.88e-0618177410340843
Pubmed

Structure and properties of the vacuolar (H+)-ATPases.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

1.88e-0618177410224039
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

COL5A1 ATP6V1A SHROOM3 ZNF609 MAP2 NAIP SRP54 FGFRL1 RNF213 WNT4 ARL15 SEC22A DENND1A DHRS7B ADGRG6 KCND3 ZNF587 OSBPL5 AKAP13 CACNA1H ZNF84 HSD11B2 ZNF839

2.24e-0614891772328611215
Pubmed

Structure, function and regulation of the vacuolar (H+)-ATPase.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

2.37e-061917749442887
Pubmed

Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

2.37e-0619177416177003
Pubmed

New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.

COL5A1 ZNF469 AKAP13

2.56e-066177320719862
Pubmed

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

2.95e-0620177422982048
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP6V1A ATP6V1B2 MAP2 IGHV1-69 PSMA6 DAPK1 GRIN2B IDH3A PTBP1 PFKP ITPKA IGHV1-69D EEF2 KRT76 DST KCND3 IGHG1 CRACDL OSBPL8 PTGES3 KNG1 VDAC3

4.09e-0614311772237142655
Pubmed

The vacuolar (H+)-ATPases--nature's most versatile proton pumps.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

4.42e-0622177411836511
Pubmed

Proton translocation driven by ATP hydrolysis in V-ATPases.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

4.42e-0622177412788495
Pubmed

Neurotransmitter release: the dark side of the vacuolar-H+ATPase.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

4.42e-0622177414597263
Pubmed

Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

4.42e-0622177417662945
Pubmed

Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

4.42e-0622177414580332
Pubmed

Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

7.54e-062517742874839
Pubmed

Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation.

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

1.04e-0527177426442671
Pubmed

Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner.

MAP2 EOMES PCNA

1.06e-059177323615279
Pubmed

FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo.

FCGR3A FCGR3B IGHG1

1.06e-059177320974962
Pubmed

Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.

ZNF354A ZNF268 ZNF91

1.06e-059177323665872
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF493 ZNF208 ZNF91

1.51e-0510177318588511
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KDM3A SHROOM3 ZNF609 KDM3B TRANK1 DST USP38 ZNF516 OSBPL5 PDCD11 ARHGAP20 RIMS2

1.89e-055291771214621295
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF493 ZNF208 ZNF91

2.08e-0511177315469996
Pubmed

Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG.

FCGR3A FCGR3B

2.58e-05217722521732
Pubmed

Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit.

ATP6V1B1 ATP6V1B2

2.58e-052177217392376
Pubmed

Changes in V-ATPase subunits of human urinary exosomes reflect the renal response to acute acid/alkali loading and the defects in distal renal tubular acidosis.

ATP6V1B1 ATP6V1B2

2.58e-052177229310826
Pubmed

INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts.

OSBPL5 OSBPL8

2.58e-052177226206935
Pubmed

Single-cell analyses identify dysfunctional CD16+ CD8 T cells in smokers.

FCGR3A FCGR3B

2.58e-052177233163982
Pubmed

Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.

FCGR3A FCGR3B

2.58e-052177226494566
Pubmed

PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas.

PTBP1 ADAR

2.58e-052177226047657
Pubmed

Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice.

ATP6V1B1 ATP6V1B2

2.58e-052177217898041
Pubmed

Estrogen contributes to gender differences in mouse ventricular repolarization.

KCNA5 KCND3

2.58e-052177219608983
Pubmed

Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.

FCGR3A FCGR3B

2.58e-052177223917248
Pubmed

Evidence for gene recombination in FCGR3 gene variants.

FCGR3A FCGR3B

2.58e-052177219320901
Pubmed

Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes.

FCGR3A FCGR3B

2.58e-052177225966632
Pubmed

The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein.

FCGR3A FCGR3B

2.58e-05217722967436
Pubmed

Human zinc finger gene ZNF23 (Kox16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF32 (Kox30) to chromosome region 10q23-q24.

ZNF23 ZNF32

2.58e-05217728500793
Pubmed

N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease.

GRIN2B RIMS2

2.58e-052177238012808
Pubmed

Immunoglobulin GM and FcγRIIIa genotypes influence cytotoxicity of neuroblastoma cells.

FCGR3A IGHG1

2.58e-052177224662005
Pubmed

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex.

FCGR3B IGHG1

2.58e-052177210917521
Pubmed

Oxysterol-binding protein related-proteins (ORPs) 5 and 8 regulate calcium signaling at specific cell compartments.

OSBPL5 OSBPL8

2.58e-052177229748134
Pubmed

NMDA Receptor GluN2B Subunit Is Involved in Excitotoxicity Mediated by Death-Associated Protein Kinase 1 in Alzheimer's Disease.

DAPK1 GRIN2B

2.58e-052177236502323
Pubmed

Low copy numbers of FCGR3A and FCGR3B associated with Chinese patients with SLE and AASV.

FCGR3A FCGR3B

2.58e-052177228355982
Pubmed

ORP5/ORP8 localize to endoplasmic reticulum-mitochondria contacts and are involved in mitochondrial function.

OSBPL5 OSBPL8

2.58e-052177227113756
Pubmed

The human low affinity immunoglobulin G Fc receptor III-A and III-B genes. Molecular characterization of the promoter regions.

FCGR3A FCGR3B

2.58e-05217727836402
Pubmed

Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells.

FCGR3A FCGR3B

2.58e-052177225816339
Pubmed

Death-associated protein kinase 1 suppresses hepatocellular carcinoma cell migration and invasion by upregulation of DEAD-box helicase 20.

DAPK1 DDX20

2.58e-052177232449268
Pubmed

Semaphorin 7A inhibits platelet production from CD34+ progenitor cells.

SEMA7A CD34

2.58e-052177222448926
Pubmed

The loss of the CD16 B73.1/Leu11c epitope occurring in some primary immunodeficiency diseases is not associated with the FcgammaRIIIa-48L/R/H polymorphism.

FCGR3A FCGR3B

2.58e-052177220664961
Pubmed

FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene.

FCGR3A FCGR3B

2.58e-052177234108956
Pubmed

The covalent structure of a human gamma G-immunoglobulin. VII. Amino acid sequence of heavy-chain cyanogen bromide fragments H1-H4.

IGHV1-69 IGHG1

2.58e-05217725489771
Pubmed

Presence of serum autoantibodies to vacuolar H+ -ATPase in patients with renal tubular acidosis.

ATP6V1B1 ATP6V1B2

2.58e-052177230821427
Pubmed

The human natural killer cytotoxic cell line NK-92, once armed with a murine CD16 receptor, represents a convenient cellular tool for the screening of mouse mAbs according to their ADCC potential.

FCGR3A FCGR3B

2.58e-052177223770975
Pubmed

Exploring putative inhibitors of Death Associated Protein Kinase 1 (DAPK1) via targeting Gly-Glu-Leu (GEL) and Pro-Glu-Asn (PEN) substrate recognition motifs.

DAPK1 GRIN2B

2.58e-052177228858643
Pubmed

Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.

FCGR3A FCGR3B

2.58e-052177222290871
Pubmed

Characterization of the human Fc gamma RIIB gene promoter: human zinc-finger proteins (ZNF140 and ZNF91) that bind to different regions function as transcription repressors.

ZNF140 ZNF91

2.58e-052177211470777
Pubmed

Fcγ receptor IIIb polymorphism and use of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis.

FCGR3A FCGR3B

2.58e-052177220980704
Pubmed

Nucleotide sequence of a new Fc gamma receptor IIIB allele that codes for a neutrophil antigen.

FCGR3A FCGR3B

2.58e-052177211034564
Pubmed

Inter-Regulation of Kv4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies.

KCNA5 KCND3

2.58e-052177232709127
Pubmed

Separate promoters from proximal and medial control regions contribute to the natural killer cell-specific transcription of the human FcgammaRIII-A (CD16-A) receptor gene.

FCGR3A FCGR3B

2.58e-05217728940055
Pubmed

FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis.

FCGR3A FCGR3B

2.58e-052177227059607
Pubmed

Fucose depletion from human IgG1 oligosaccharide enhances binding enthalpy and association rate between IgG1 and FcgammaRIIIa.

FCGR3A IGHG1

2.58e-052177215037082
Pubmed

Association of FCGR3A and FCGR3B copy number variations with systemic lupus erythematosus and rheumatoid arthritis in Taiwanese patients.

FCGR3A FCGR3B

2.58e-052177225154742
Pubmed

Initial crystallographic study of human PCNA in complex with a peptide containing the noncanonical PIP-box sequence of human DNA polymerase iota.

POLI PCNA

2.58e-052177218931444
Pubmed

A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms.

FCGR3A FCGR3B

2.58e-05217722525780
Pubmed

ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.

OSBPL5 OSBPL8

2.58e-052177228970484
Pubmed

DAPK1 Mediates LTD by Making CaMKII/GluN2B Binding LTP Specific.

DAPK1 GRIN2B

2.58e-052177228614711
Pubmed

Characterization of the mouse Kid1 gene and identification of a highly related gene, Kid2.

ZNF354A ZNF354B

2.58e-052177210564808
Pubmed

Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms.

ATP6V1B1 ATP6V1B2

2.58e-05217727945239
Pubmed

FcgammaRIII expression on cultured human keratinocytes and upregulation by interferon-gamma.

FCGR3A FCGR3B

2.58e-052177212445195
Pubmed

Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions.

FCGR3A FCGR3B

2.58e-05217722526846
Pubmed

B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.

FCGR3A FCGR3B

2.58e-052177218292508
Pubmed

Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice.

WNT4 MAP3K1 MAPK13 MAP2K7

2.67e-0534177423300479
Pubmed

LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.

KCNA5 KCND3 CD34 CACNA1H

2.67e-0534177426378152
Pubmed

Id4 regulates neural progenitor proliferation and differentiation in vivo.

MAP2 EOMES PCNA

2.76e-0512177315469968
Pubmed

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

KDM3A RNF213 CEP350 TRANK1 PDCD11 ULK2

2.98e-05116177621282530
Pubmed

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.

COL5A1 ZNF469 AKAP13 ARHGAP20

3.00e-0535177423291589
Pubmed

Defining the membrane proteome of NK cells.

KDM3A ATP7A MAN2A1 RNF213 PTBP1 CD320 PFKP ADAR PAICS DHRS7B CEP350 CMTM6 EEF2 DDX50 OSBPL5 OSBPL8 AKAP13 DDX20

3.15e-0511681771819946888
Pubmed

Desmoplakin (Dsp) conditional knockout in NR5A1+ somatic cells affects germ cell survival in developing mouse gonads.

WNT4 HELB PCNA

3.57e-0513177335119382
Pubmed

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

ZNF493 ZNF208 ZNF91

3.57e-0513177319850934
Pubmed

Functional suppression of Kcnq1 leads to early sodium channel remodelling and cardiac conduction system dysmorphogenesis.

KCNA5 KCND3 PCNA

4.53e-0514177323542581
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

COL5A1 ATP6V1A PSMA6 RANBP6 RNF213 PTBP1 PFKP DENND1A PAICS EEF2 DST DDX50 OSBPL8 PDCD11 DDX20 ATM PTGES3 VPS53 PCNA VDAC3

4.87e-0514401772030833792
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SHROOM3 SEMA7A KDM3B FGFRL1 NPHP4 DENND1A DST SSH1 ZNRF3 ZNF516 OSBPL5 PDCD11 AKAP13 CACNA1H MAPKBP1 ZNF839 ULK2

5.39e-0511051771735748872
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF493 ZNF208 ZNF91

5.64e-0515177315885501
Pubmed

DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.

EOMES ATM PCNA

6.91e-0516177328123024
Pubmed

Genome-wide association of body fat distribution in African ancestry populations suggests new loci.

RREB1 DENND1A MAP3K1

6.91e-0516177323966867
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ATP6V1A AFF2 PSMA6 DAPK1 SAXO1 PTBP1 PFKP PAICS EEF2 DST AKAP13 ZNF561 PTGES3 VDAC3

7.23e-058071771430575818
Pubmed

Fc gamma receptor genes as risk markers for localized aggressive periodontitis in African-Americans.

FCGR3A FCGR3B

7.70e-053177212027254
Pubmed

Analysis of Fc gamma RIII (CD16) membrane expression and association with CD3 zeta and Fc epsilon RI-gamma by site-directed mutation.

FCGR3A FCGR3B

7.70e-05317721825220
Pubmed

Polymorphism of Fc gamma RIIa may affect the efficacy of gamma-globulin therapy in Kawasaki disease.

FCGR3A FCGR3B

7.70e-053177216133986
Pubmed

DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.

POLI PCNA

7.70e-053177227407148
Pubmed

Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.

FCGR3A FCGR3B

7.70e-053177228427365
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF140 ZNF609 ZNF354A ZNF266 ZNF493 ZNF670 ZNF273 ZNF268 ZNF674 ZNF208 E4F1 ZNF225 RREB1 ZNF354B ZNF850 BNC1 ZNF14 ZNF836 ZNF469 ZNF23 ZNF32 ZNF587 ZNF516 ZNF561 ZNF84 ZNF91 ZNF417 ZNF541 ZNF345 ZNF239

9.31e-157181353028
GeneFamilyV-type ATPases

ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1G1

2.36e-05231354415
GeneFamilyOlfactory receptors, family 3

OR3A4P OR3A1

8.14e-0461352150
GeneFamilyAdhesion G protein-coupled receptors, subfamily G

ADGRG4 ADGRG6

1.13e-0371352917
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

RNF213 DAPK1 ADAR HELB TRANK1 GIMAP8 FCGR3A HERC6

1.26e-0619817684b078714c49e7befb7b113d72485e712236d35fa
ToppCellIonocyte|World / Class top

ATP6V1A ATP7A CEL MAP2 PFKP PPP1R1A GIMAP8

5.23e-061701767d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCelldroplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A SRP54 FGFRL1 ITPKA ZNRF3 ADAMTS16 ARHGAP28

6.56e-061761767533d544852038c0612aacf87f4b1c88ff7aace82
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

ATP6V1A ATP7A MAN2A1 CEL PFKP EOMES CACNA1H

7.88e-0618117674a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L GRIN2B ATP6AP1L ITPKA PPP1R1A TRANK1 CRACDL

8.47e-061831767bf7f1cb55ed55981b8b355d5774055c96e658ff2
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

IL15RA SEMA7A RNF213 ADAR CEP350 TRANK1 DST

8.47e-0618317678f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L GRIN2B ATP6AP1L ITPKA PPP1R1A TRANK1 CRACDL

8.47e-0618317679533db4db2c6ae78d7ca1682cf4efed12183396f
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

GPR155 RNF213 SPOCK2 ADAR HELB TRANK1 HERC6

1.01e-0518817676f8946d4710f6e32c937213f99b790b098b8819c
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L GRIN2B ITPKA PPP1R1A TRANK1 CRACDL ARHGAP20

1.04e-0518917673e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L GRIN2B ITPKA PPP1R1A TRANK1 CRACDL ARHGAP20

1.04e-051891767851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L GRIN2B ITPKA PPP1R1A TRANK1 CRACDL ARHGAP20

1.08e-0519017671c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DAPK1 ADGRG6 ZNF32 GIMAP8 DDX50 ATM MAPKBP1

1.08e-05190176763018acb7ad80415e861643162abdc2e55968ee4
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

IL15RA MAP2 RNF213 ADAR TRANK1 HERC6 KNG1

1.12e-0519117672da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L CEL MAP2 SPOCK2 WNT4 PPP1R1A ZNF516

1.12e-051911767d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GIPC2 CD320 ARL15 GIMAP8 CD34 CRYBG3 ZNF541

1.20e-0519317673a9fe4e709c09ec787c71bdd6b58a71c419896de
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 EOMES TRANK1 FCGR3A OSBPL5 ATM HERC6

1.41e-0519817670e918e9db9b884f5328d438e90efe065e27266ee
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 EOMES TRANK1 FCGR3A OSBPL5 ATM HERC6

1.41e-051981767ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNF213 EOMES TRANK1 FCGR3A OSBPL5 ATM HERC6

1.41e-051981767fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF213 EOMES TRANK1 FCGR3A OSBPL5 ATM HERC6

1.41e-0519817671ef3a6bd681c223eed58300348adfef89df5563c
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK_activated|COVID-19_Severe / Disease group, lineage and cell class

RNF213 EOMES TRANK1 FCGR3A OSBPL5 ATM HERC6

1.46e-051991767edf5f80b4c299e6bf462675f2cd3329d86c923d8
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-Treg|Leuk-UTI / Disease, condition lineage and cell class

GPR155 SPOCK2 EEF2 ZNRF3 LINC02694 ZNF541 ZNF239

1.46e-051991767100f45e04f284551b29ef0406476bdc347ddbf7e
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

RNF213 SPOCK2 ADAR HELB TRANK1 IGHG1 HERC6

1.46e-051991767952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

ZNF609 RNF213 SPOCK2 ADAR TRANK1 DST HERC6

1.51e-052001767d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCellhealthy_donor|World / Disease condition, Lineage, Cell class and subclass

SPOCK2 EEF2 FCGR3A FCGR3B OSBPL5 ATM ZNF91

1.51e-052001767afd4d5609adaa470e3d880f8be4a4d55e162b3d6
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_activated|COVID-19_Severe / Disease, condition lineage and cell class

RNF213 EOMES TRANK1 FCGR3A OSBPL5 ATM HERC6

1.51e-0520017676a77f9643646bafc1157bf1fc1e4c614860ee642
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

RNF213 ADAR EOMES TRANK1 FCGR3A FCGR3B HERC6

1.51e-0520017672281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 MAP3K1 KRT76 ADAMTS16 POLI PLEKHH2

1.70e-05136176682b1d6d839c0d0c68e0960549f688138479defcc
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF354A SPOCK2 NPHP4 ADGRG4 KCND3 ZNF84

2.84e-0514917664b44108c40376a6b73258df40d2424e68f991383
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STARD8 WNT4 ATP6AP1L ITPKA CRACDL ADAMTS16

3.68e-0515617662cd007b423c2395c5ce331902e7f27c805755eb3
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GCFC2 CEL COL6A6 ZNF208 EEF2 ARHGAP20

3.81e-05157176662f029831c420d3e9580822177545eb7fdf4d0a3
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-LMPP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MOK SHROOM3 BEND4 ZNF225 ZNF839 ZNF239

4.24e-05160176660fa1c717410aad7e8647703cb416cd7617cac29
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STARD8 WNT4 ARL15 ATP6AP1L ITPKA CRACDL

4.39e-051611766e3327c296d48e821004e61a573abb75624a6f040
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L NPHP4 ITPKA TRANK1 CRACDL ZNF541

5.03e-0516517661b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L NPHP4 ITPKA TRANK1 CRACDL ZNF541

5.03e-051651766b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT2B SPOCK2 BDKRB1 BNC1 KCNA5 KCND3

5.38e-051671766e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCelldroplet-Marrow-BM-30m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 ATP6V1G1 ACOD1 CMTM6 FCGR3B MAPK13

5.38e-051671766f90cf0f29c14df4f211193326699e599ef955fa4
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L GRIN2B NPHP4 ITPKA TRANK1 CRACDL

5.56e-051681766b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L GRIN2B NPHP4 ITPKA TRANK1 CRACDL

5.56e-051681766b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STARD8 SEMA7A ARL15 RGS12 CD34 CRYBG3

5.75e-05169176641ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STARD8 SEMA7A ARL15 RGS12 CD34 CRYBG3

5.75e-05169176642782c61592742190ab0cba8a94f8bdf9c278f90
ToppCelldroplet-Marrow-nan-24m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 ATP6V1G1 ACOD1 CMTM6 FCGR3B MAPK13

6.13e-051711766b3ea26d181f91ea07074f403e7dca9b6b671b1a2
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATXN7L2 SPOCK2 EOMES ZNF14 ZNF469 FCGR3A

6.13e-051711766187b396059f8802265f54bad2b4882cebb809419
ToppCell11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

WNT2B SPOCK2 GRIN2B BDKRB1 BNC1 KCNA5

6.54e-0517317666989c9cebcd81eccceac7e5a86152676ee959386
ToppCellIonocyte-iono-2|World / Class top

ATP6V1A ATP7A CEL MAP2 PFKP PPP1R1A

6.54e-051731766e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCelldroplet-Marrow-nan-18m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 ACOD1 CMTM6 FCGR3A FCGR3B MAPK13

6.54e-05173176603cee3d24bc433e91a867ce951589de64a0538af
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 DAPK1 SPOCK2 RGS12 MAP3K1 PLEKHH2

7.19e-051761766327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

MAN2A1 ZNF674 RNF213 DNAAF8 DST PDCD11

7.19e-0517617663de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AHSA2P RNF213 EOMES TRANK1 FCGR3A FCGR3B

7.42e-051771766d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AHSA2P RNF213 EOMES TRANK1 FCGR3A FCGR3B

7.42e-051771766f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

MAN2A1 ZNF674 RNF213 DENND1A DST PDCD11

7.42e-05177176682fdd6185b368f54f03de389427cbe3071d21a99
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

AHSA2P RNF213 EOMES TRANK1 FCGR3A FCGR3B

7.42e-0517717666978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

AHSA2P RNF213 EOMES TRANK1 FCGR3A FCGR3B

7.42e-051771766936ab2b180a052387124f68d0c7f41c0b164e748
ToppCelldroplet-Marrow-nan-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 ACOD1 CMTM6 FCGR3A FCGR3B MAPK13

7.42e-0517717665d70fe2b0592362d664b3b4c84eb450ec2335957
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AHSA2P RNF213 EOMES TRANK1 FCGR3A FCGR3B

7.42e-051771766d5aeda113afaa2425874394610344570c9078478
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1B1 CEL ADAMTS16 CRYBG3 HSD11B2 KNG1

7.42e-051771766c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCelldroplet-Marrow-nan-18m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 ACOD1 CMTM6 FCGR3A FCGR3B MAPK13

7.42e-05177176648bcf603ec9593eedd81f3831cf9fde89fad368f
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GIPC2 ZNF354B BDKRB1 SPATA33 ZNF469 FAM216A

8.14e-0518017665c9d2d44d840cd4ec7d42d43446ba2b689e7ec43
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B1 AFF2 WNT4 PPP1R1A HSD11B2 KNG1

8.14e-051801766fc5b9d0e3215652e490ca72d69f776e9725608b2
ToppCellCV-Severe-4|Severe / Virus stimulation, Condition and Cluster

KDM3A ATP6V1B2 SEMA7A PFKP PAICS FAM216A

8.14e-051801766cf84a01e6a33e5d27ad7be1d9069a0370b5116d1
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B1 AFF2 WNT4 PPP1R1A HSD11B2 KNG1

8.14e-0518017666763b22f2383931c747b37cd0ae2f60b08f64d90
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GIPC2 ZNF354B BDKRB1 SPATA33 ZNF469 FAM216A

8.14e-051801766c60e74fbbd815a0251253a19dc520a254b2e1762
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 SPOCK2 RGS12 MAP3K1 ZNRF3 RIMS2

8.39e-0518117669d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 SPOCK2 MAP3K1 ADGRG6 ADAMTS16 PLEKHH2

8.65e-0518217665e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ATP6V1A ATP6V1B1 ATP7A CEL PFKP HSD11B2

8.65e-0518217666e7dac78dc030f74e546b9f6db07556e9bb13ac2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 SPOCK2 RGS12 MAP3K1 ZNRF3 RIMS2

8.65e-051821766eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ATP6V1A ATP6V1B1 ATP7A CEL PFKP HSD11B2

8.65e-051821766cd972d30519db706477c6b0c901165b81b74abed
ToppCellCV-Severe-4|CV / Virus stimulation, Condition and Cluster

KDM3A ATP6V1B2 SEMA7A PFKP PAICS FAM216A

8.65e-051821766c19bbc43d97c426aec37414f46f667a19b62a257
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

AHSA2P RNF213 EOMES TRANK1 FCGR3A FCGR3B

8.92e-05183176622bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A6 WNT2B WNT4 BNC1 KRT76 ARHGAP20

8.92e-051831766ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCellControl-CD8+_T_activated|Control / Disease group and Cell class

ATP6V1B2 PSMA6 PFKP ADAR HELB OSBPL5

9.19e-051841766b86cc48b744b3206880ec1373fe6068e14bf9680
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF670 ATP6AP1L BDKRB1 RIMS2 MAP2K7 ZNF345

9.47e-05185176660e223cd0ed3022e3f98ce6b766bedd14c534885
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 SPOCK2 MAP3K1 ADGRG6 ADAMTS16 PLEKHH2

9.75e-0518617665c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IL15RA RNF213 PFKP ACOD1 GIMAP8 HERC6

1.00e-04187176672e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCellwk_15-18-Mesenchymal-Mesothelial-Late_mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

WNT2B SPOCK2 GRIN2B BDKRB1 BNC1 IGHG1

1.03e-04188176638a53f99f1876359983936403aefca93281d10fd
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L WNT4 PPP1R1A DST ZNF516 AKAP13

1.03e-041881766a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-ELP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CEL IGHV1-69 PAICS IGHV1-69D EEF2 CD34

1.06e-041891766af391c321753743709e2da01a5aa7782d8cc54e3
ToppCellIPF-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

COL5A1 SEMA7A MAP2 SPOCK2 ITPKA DST

1.06e-0418917664178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCellmoderate-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ATP6V1A ATP6V1B1 ATP7A CEL DST HSD11B2

1.06e-0418917666011b747e27d61d222380a7bffdd921a68e9b657
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ATP6V1B1 ATP7A MAN2A1 CEL DST HSD11B2

1.10e-04190176605a2c3549b68f49081723bf35db14974274419d5
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM3 STARD8 MAP2 PFKP PPP1R1A DST

1.10e-041901766c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A SHROOM3 ZNF208 ARL15 ADAMTS16 HSD11B2

1.10e-041901766b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

DAPK1 ADGRG6 DST ARHGAP28 CRYBG3 PLEKHH2

1.10e-04190176662a3ec1ae0829602b0569cc051210551644f1d46
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM3 STARD8 MAP2 PFKP PPP1R1A DST

1.10e-0419017665cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCellPSB-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ATP7A MAN2A1 CEL KIAA1210 DST HSD11B2

1.13e-0419117668f4637e801554e2343b974fe7794f01dd2151418
ToppCellwk_15-18-Mesenchymal-Mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

WNT2B SPOCK2 GRIN2B BDKRB1 BNC1 IGHG1

1.13e-041911766b5374674312ff5803a1d369f5533027532344679
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L SPOCK2 WNT4 PPP1R1A DST AKAP13

1.13e-0419117663387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GIPC2 CD320 ARL15 GIMAP8 CD34 CRYBG3

1.13e-04191176604c7aa2e39fdd08ca24c10d43b29a5e41a73b9e0
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GIPC2 CD320 ARL15 GIMAP8 CD34 CRYBG3

1.13e-041911766db8dd6bbba803585bdd6a55d5c403d383f2e9acf
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM3 STARD8 MAP2 PFKP PPP1R1A DST

1.16e-041921766e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM3 STARD8 MAP2 PFKP PPP1R1A DST

1.16e-04192176661c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

COL6A6 MAP2 DST OSBPL8 ARHGAP28 PLEKHH2

1.16e-04192176662904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellfacs-Tongue-nan-3m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1A MAP2 CMTM6 AKAP13 GRHL3 VPS53

1.19e-04193176633437fdb417d78463caee14a9f0e094da1733829
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

COL5A1 COL6A6 DST ARHGAP28 PLEKHH2 ARHGAP20

1.19e-041931766acad568621ed677031797b8c2e34dafea798d681
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MAP3K1 ADGRG6 DST ARHGAP28 PLEKHH2 ARHGAP20

1.23e-041941766b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL5A1 COL6A6 DST ARHGAP28 PLEKHH2 ARHGAP20

1.23e-04194176635f132cc38ac133be01834ed0946188aa0757eb4
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL5A1 ATP6AP1L KRT24 TRPM1 ZNF541

1.24e-04122176537612ad087d9c11d4a3466244ab36224de31930b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF213 DAPK1 PFKP MAP3K1 DST PLEKHH2

1.26e-041951766938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNDIG1L SPOCK2 WNT4 PPP1R1A DST ZNF516

1.26e-041951766bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL5A1 ADGRG6 DST ARHGAP28 PLEKHH2 ARHGAP20

1.26e-0419517661cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1B1 CEL ARL15 ADAMTS16 HSD11B2 KNG1

1.26e-0419517663f517c6fc372bdcaf45b3af373414f13cbebd4ba
DrugSant7

PSMA6 EEF2 FCGR3A FCGR3B

3.04e-06141734CID000128225
Diseaselevel of low affinity immunoglobulin gamma Fc region receptor III-A in blood serum

FCGR3A FCGR3B

3.15e-0521662OBA_2040305
Diseasebasophil percentage of leukocytes

PADI4 AFF2 HELB ZNF469 ARFRP1 FCGR3A FCGR3B OSBPL8

7.43e-052431668EFO_0007992
DiseaseLupus Vasculitis, Central Nervous System

FCGR3A FCGR3B

9.40e-0531662C0752332
DiseaseLupus Meningoencephalitis

FCGR3A FCGR3B

9.40e-0531662C0752334
DiseaseNeuropsychiatric Systemic Lupus Erythematosus

FCGR3A FCGR3B

9.40e-0531662C0752335
Diseasefollicular lymphoma (implicated_via_orthology)

ATP6V1B1 ATP6V1B2

3.11e-0451662DOID:0050873 (implicated_via_orthology)
DiseaseCardiac Arrhythmia

PPP1R1A KCND3 KNG1

3.67e-04251663C0003811
Diseasecutaneous melanoma, hair color

GIPC2 RREB1 MAP3K1 ARHGAP20

4.18e-04621664EFO_0000389, EFO_0003924
Diseasebasophil count

PADI4 AFF2 RREB1 HELB EOMES ZNF469 ARFRP1 FCGR3A FCGR3B OSBPL8

4.31e-0448316610EFO_0005090
Diseaseeye measurement

COL5A1 ZNF469 AKAP13

4.63e-04271663EFO_0004731
Diseasenephronophthisis (is_implicated_in)

RPGRIP1L NPHP4

4.65e-0461662DOID:12712 (is_implicated_in)
Diseasealkaline phosphatase measurement

GIPC2 CEL FGFRL1 WNT4 RREB1 ATP6AP1L ZNF14 SPATA33 TRANK1 ZNRF3 FCGR3A FCGR3B PINX1 AKAP13 PLEKHH2

6.43e-04101516615EFO_0004533
Diseaselow affinity immunoglobulin gamma Fc region receptor II-a/b measurement

FCGR3A FCGR3B

6.49e-0471662EFO_0008211
DiseaseNephronophthisis, familial juvenile

NPHP4 MAPKBP1

6.49e-0471662C1855681
Diseasehair colour measurement

PADI4 SHROOM3 GIPC2 RANBP6 ARL15 DENND1A MAP3K1 BNC1 SPATA33 ZNF469 AKAP13

7.58e-0461516611EFO_0007822
Diseaserenal tubular acidosis (implicated_via_orthology)

ATP6V1B1 ATP6V1B2

8.61e-0481662DOID:14219 (implicated_via_orthology)
DiseaseMeckel syndrome (implicated_via_orthology)

RPGRIP1L NPHP4

8.61e-0481662DOID:0050778 (implicated_via_orthology)
Diseaseblood urea nitrogen measurement

SHROOM3 GIPC2 DAPK1 PTBP1 ARL15 RREB1 USP38 AKAP13 LINC02694

1.09e-034521669EFO_0004741
DiseaseNephronophthisis

RPGRIP1L NPHP4

1.10e-0391662cv:C0687120
Diseaseplexin-B2 measurement

FCGR3A FCGR3B

1.10e-0391662EFO_0021867
Diseasestomach cancer (is_marker_for)

ADAR EEF2 KCNA5 ATM PCNA

1.28e-031421665DOID:10534 (is_marker_for)
DiseaseAllodynia

GRIN2B BDKRB1 CACNA1H KNG1

1.31e-03841664C0458247
DiseaseMechanical Allodynia

GRIN2B BDKRB1 CACNA1H KNG1

1.31e-03841664C2936719
DiseaseHyperalgesia, Secondary

GRIN2B BDKRB1 CACNA1H KNG1

1.31e-03841664C0751212
DiseaseHyperalgesia, Primary

GRIN2B BDKRB1 CACNA1H KNG1

1.31e-03841664C0751211
DiseaseHyperalgesia, Thermal

GRIN2B BDKRB1 CACNA1H KNG1

1.31e-03841664C0751214
DiseaseTactile Allodynia

GRIN2B BDKRB1 CACNA1H KNG1

1.31e-03841664C0751213
DiseaseHyperalgesia

GRIN2B BDKRB1 CACNA1H KNG1

1.31e-03841664C0020429
Diseaseserum alanine aminotransferase measurement

SHROOM3 PTBP1 ARL15 RGS12 MAP3K1 TRANK1 FCGR3A FCGR3B PINX1 GRHL3 PTGES3 MAP2K7 OR2H2

1.32e-0386916613EFO_0004735
DiseaseSmall Lymphocytic Lymphoma

IGHG1 ATM

1.37e-03101662C0855095
DiseaseB-CELL MALIGNANCY, LOW-GRADE

IGHG1 ATM

1.37e-03101662C1868683
DiseaseInherited neuropathies

ATP7A ZFYVE27 ATM

1.48e-03401663C0598589
Diseasecreatinine measurement

ATP6V1B1 SHROOM3 GIPC2 CEL SEMA7A PSMA6 ATP6V1G1 BEND4 ARL15 RREB1 RGS12 PLEKHH2 LINC02694 KNG1

1.55e-0399516614EFO_0004518
Diseasesciatic neuropathy (biomarker_via_orthology)

MAP2 GRIN2B CACNA1H PCNA

2.40e-03991664DOID:11446 (biomarker_via_orthology)
Diseaseintraocular pressure measurement

COL5A1 SYNDIG1L WNT2B ZNF469 ZNRF3 OR4A5 ZNF516 AKAP13 ARHGAP20

2.46e-035091669EFO_0004695
Diseaselow affinity immunoglobulin gamma Fc region receptor III-B measurement

FCGR3A FCGR3B

2.74e-03141662EFO_0008212
DiseaseMalignant neoplasm of breast

KDM3A STARD8 AHSA2P ADAR ATP6AP1L MAP3K1 EOMES EEF2 KRT76 ARFRP1 KCNA5 ATM MAP2K7 ZNF541

3.10e-03107416614C0006142
DiseaseOpioid use measurement

BEND4 KCND3

3.15e-03151662EFO_0009937
Diseaseureidopropionic acid measurement

RPGRIP1L SPOCK2

3.58e-03161662EFO_0010542
Diseasecortical surface area measurement

SHROOM3 MAP2 WNT2B FGFRL1 DAPK1 WNT4 ARL15 RREB1 DENND1A ATP6AP1L MAP3K1 ZNF469 KCNA5 USP38 ARHGAP28 LINC02694

3.92e-03134516616EFO_0010736
DiseaseAntihypertensive use measurement

ZNF493 WNT2B USP38 ZNRF3 CACNA1H PTGES3

3.98e-032651666EFO_0009927
Diseaseesophageal carcinoma, gastric carcinoma

BDKRB1 TRPM1

4.05e-03171662EFO_0000178, EFO_0002916
Diseaselow affinity immunoglobulin gamma Fc region receptor II-a measurement

FCGR3A FCGR3B

4.05e-03171662EFO_0021969
DiseaseMoyamoya Disease

ATP7A RNF213

4.05e-03171662C0026654
Diseaseidiopathic pulmonary fibrosis

GIPC2 AKAP13 MUC5AC

4.10e-03571663EFO_0000768
Diseasepsoriasis

GIPC2 CEL PSMA6 POLI AKAP13 GRHL3

4.60e-032731666EFO_0000676
DiseaseLewy body dementia (is_marker_for)

MAP2 PCNA

5.05e-03191662DOID:12217 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
LKTKSCSGVEFSTSG

VDAC3

31

Q9Y277
KATVSSCGELALKGF

NAIP

686

Q13075
LKQVEGEASCSSRKG

AHSA2P

61

Q719I0
GEASCSSRKGKLIFF

AHSA2P

66

Q719I0
ASKKFSGSLSCEAVS

EOMES

51

O95936
SGSGKTTLVESLKCG

DAPK1

696

P53355
SRTRCGGRKDSKTTA

BDKRB1

236

P46663
AKGGSLRESQGVCSK

EGFL8

26

Q99944
TGSGKTSLLSKLCSE

ARL15

41

Q9NXU5
KSKASDTCLDVIGGR

CRYBG3

2886

Q68DQ2
SSDGSSRCQIKVGYK

ADGRG4

3011

Q8IZF6
SQTKFCGATAKGLSF

ADGRG6

106

Q86SQ4
RTEGKFCATFKGISV

AFF2

956

P51816
SCGLGKRKRSVQSGE

BEND4

431

Q6ZU67
CTSKQGVLKRESGSD

AKAP13

1426

Q12802
ERNSLGTKKGRVFCT

BNC1

346

Q01954
GVFTIKAGRKAVSCT

C14orf28

31

Q4W4Y0
LRSKAGKSSGEKIGC

GIPC2

206

Q8TF65
LGKGRESALSLACSK

ANKRA2

211

Q9H9E1
AKSGTGKTCVFSTIA

DDX20

106

Q9UHI6
LITGCDSGFGKETAK

HSD11B2

86

P80365
FTITKGLRGAKTTFD

CEL

371

P19835
SGCRGLSAKTKTALS

ATXN7L2

596

Q5T6C5
GGKFCEGSTRTLKLC

ADAMTS16

621

Q8TE57
LSLDTGTLEKKSGAC

ATP7A

146

Q04656
KAFRTCSKESGLAET

RBAKDN

6

A6NC62
CKKSFSGRSQGFSGR

KRT76

6

Q01546
ATRGKLSSKCSVVLG

PADI4

216

Q9UM07
TASITCSGDKLGDKY

IGLV3-1

36

P01715
RTVEGKRKAFSTCSS

OR13G1

226

Q8NGZ3
INSAKGRRKAFGTCS

OR2H2

226

O95918
KTIAGKIFGSICSLS

KCND3

376

Q9UK17
SGFKRKAGTSSLTEC

IL15RA

61

Q13261
SKGTGLFCSTTQGKI

MAN2A1

1081

Q16706
KSGRIFCTASLIGTK

RPGRIP1L

706

Q68CZ1
IVKERRCGAKTSAGT

GPR155

766

Q7Z3F1
SVKVSCKASGGTFSS

IGHV1-69

36

P01742
SCSKRDGGKVDTSAT

DST

3996

Q03001
TGVSDCSGGTDKKLR

CD320

111

Q9NPF0
SCAKDGVKFSASGEL

PCNA

161

P12004
GGTTSFQCKVRSDVK

FGFRL1

261

Q8N441
GRLVDSKAKTRSAGC

MAP2K7

266

O14733
NSAEGRKKAFATCSS

OR2T4

261

Q8NH00
IRSVEGRKKAFSTCG

OR3A1

231

P47881
IRSAEGRKKAFSTCS

OR3A4P

231

P47883
GRGKKFTTDDSICVL

PFKP

706

Q01813
SSRSKTDLDCIFGKR

PINX1

136

Q96BK5
CLTASFLKKRGTGET

HERC6

416

Q8IVU3
SGLCKGRSVLGTDTK

KDM3B

566

Q7LBC6
CSGQGRDSSKTRVTK

KRT24

486

Q2M2I5
YGSVCSAIDKRSGEK

MAPK13

36

O15264
RKSGASVKVSCSFSG

IGHV1-38-4

31

P0DTW3
LKLGDFGSCRSVYSK

MOK

141

Q9UQ07
TGTTCSKAIKIFLGG

MUC5AC

956

P98088
SVKVSCKASGGTFSS

IGHV1-69D

36

A0A0B4J2H0
AELRGAKKFSVSSCR

CRACDL

566

Q6NV74
EDGSKGRSKSRCTST

PLEKHH2

291

Q8IVE3
GKKRDGSLQTLSCGF

NPHP4

116

O75161
RIEGIKKADGSCSTD

ITPKA

331

P23677
KKADGSCSTDFKTTR

ITPKA

336

P23677
ACLGKVSSSGKRARE

NUTM1

521

Q86Y26
LSGKKSISFVGCATQ

OR2AE1

86

Q8NHA4
RKDGFCLSGSILAKS

OSBPL8

526

Q9BZF1
SGRLCAFITKVKKGS

RIMS2

691

Q9UQ26
LKICSSEGRKKAFST

OR8J1

226

Q8NGP2
KGQASVKVIDFGSSC

DYRK4

241

Q9NR20
IKTLTCAFLDSGGTK

ATM

1806

Q13315
DIKTAFSDCTSKIGR

ARFRP1

146

Q13795
SSGKEGSLTKCRQIY

CRNKL1

721

Q9BZJ0
LTKDLGGNAKCSDFT

IDH3A

341

P50213
CLSTDFSSQKGVKGV

GRHL3

356

Q8TE85
GVQRKVSGSRGSFCK

KCNA5

551

P22460
CGNSARIGAVKRKSS

KDM3A

251

Q9Y4C1
NRCVKGDSLSLKGET

ADAR

891

P55265
NSFTGGICKTVKSSR

C6

211

P13671
RDIDLSCGNGSSKVK

GCFC2

241

P16383
TACLSFSLSAGKEAK

C3orf20

231

Q8ND61
LGKCRSGKSATGNAI

GIMAP8

16

Q8ND71
SGSEGRAIIFCETKK

DDX50

386

Q9BQ39
CASKGLDIESTSKRV

CEP350

2956

Q5VT06
KEADSGSRCASRKQG

DNAAF8

341

Q8IYS4
TKTTGFCATRRSSKG

COL5A1

56

P20908
KATLKDSGSYFCRGL

FCGR3B

161

O75015
RGKKADSTFCITSSG

MAPKBP1

241

O60336
KQRFGFCRLSSGAKS

DENND1A

81

Q8TEH3
AAASKFLGLSSTKCR

ACOD1

171

A6NK06
VTGTKGKGSTCAFTE

FPGS

101

Q05932
GLSGCEFKGRSLKQS

KIAA1210

546

Q9ULL0
KAATGECTATVGKRS

KNG1

101

P01042
KSTSGGTAALGCLVK

IGHG1

16

P01857
GKSTLTDSLVCKAGI

EEF2

31

P13639
SKCGKSFRESGALTR

E4F1

251

Q66K89
VITGATSGLGKECAK

DHRS7B

56

Q6IAN0
AGGTEKKETAIFGSC

CCDC168

1666

Q8NDH2
EGIKTGYASKTRCKS

FAM216A

206

Q8WUB2
KATLKDSGSYFCRGL

FCGR3A

161

P08637
LFGCKFSLKTDTGDT

CACNA1H

936

O95180
GKSREKFQGKGSVSC

POLI

546

Q9UNA4
SAFSVDCKGAGKISS

SEC22A

166

Q96IW7
TSSCAEFKKDRGEGL

CD34

196

P28906
KGGCGKTTIVSRLFK

HELB

476

Q8NG08
KGAKGLASFSTCELI

COL6A6

1721

A6NMZ7
KAEGAAVKALSTCGS

OR56A1

236

Q8NGH5
KDGFCISGSITAKSR

OSBPL5

491

Q9H0X9
SQEKRGKALSTCSSG

OR4A5

226

Q8NH83
KSQAGEGRRKAISTC

OR4D10

226

Q8NGI6
TGKGLCATKLSASSE

MAP3K1

911

Q13233
LTGVSRLAGGSCTKK

ARHGAP20

21

Q9P2F6
GTSKAISKGDFRLAS

SYNDIG1L

186

A6NDD5
GTSGIDAKKTSCEFT

ATP6V1B2

101

P21281
TSGIDARKTTCEFTG

ATP6V1B1

96

P15313
KKAKGCTIIFTDRSG

TCAIM

261

Q8N3R3
FVGLQGSGKTTTCSK

SRP54

106

P61011
LQIKKCGRFEGSSTT

SAXO1

326

Q8IYX7
FERDGKACSTLSLSG

SHROOM3

1061

Q8TF72
AKTGGTQTDLFTCGK

TCEA1

251

P23193
KRASSGVELGDCKIS

TEX45

226

Q8NA69
FGIKTSGLEAKATAC

RANBP6

676

O60518
CSLSIRDARKGDSGK

SIGLEC12

231

Q96PQ1
SEKVSKASSFRSCRG

STARD8

156

Q92502
GVDFSSKESKSCTIG

SSH1

126

Q8WYL5
SSLGTSGVDCNRKRK

ARNTL

26

O00327
SGVDCNRKRKGSSTD

ARNTL

31

O00327
KTAGGVCKFSGQRLS

ADGRD2

51

Q7Z7M1
KVKSSDFYITLGTGC

CMTM6

101

Q9NX76
GSKAKGRSSICLQAS

LINC02694

26

Q8NAA6
AGARTFCEEQKKGST

SPATA33

6

Q96N06
AGIKTAFTRKCGETA

PAICS

71

P22234
CGFKATAAGVKQTES

PSMA6

161

P60900
ETGCGKTRLIKFLSD

RNF213

2421

Q63HN8
CVVSSLGITDRGKKS

PDCD11

151

Q14690
VECGKTFITSSRRSK

ZNF561

396

Q8N587
VLLRSSKKGAEGSAC

ZNF516

151

Q92618
EECGKGFSIFSTLTK

ZNF273

321

Q14593
KLGSTAKSFECTTFG

ZNF268

171

Q14587
GTSCVVAVKAGFSIK

RGS12

971

O14924
FEKSKLTFSCLGGSD

PTGES3

31

Q15185
DTCGKSFKFLGTLSR

RREB1

1396

Q92766
VISGGSSDLKYKARC

SMC1B

651

Q8NDV3
KTGKCATVSAAVAER

TSPYL1

156

Q9H0U9
SEGIFRLSGCTAKVK

ARHGAP28

416

Q9P2N2
GECGKSYSRKSSLIQ

ZNF587

271

Q96SQ5
GECGKSYSRKSSLIQ

ZNF417

271

Q8TAU3
KSKKERSEGVGTCSE

ZNF609

166

O15014
KAKEAAALGSRGSCS

ATP6V1G1

56

O75348
VNIGSTKGSCLDKRD

SEMA7A

111

O75326
AFGCGKTVISQSLSK

ATP6V1A

251

P38606
SCLSRLSGKSETGKT

USP38

431

Q8NB14
RFSGCTLTDGTLKKL

VPS53

361

Q5VIR6
CVKRKTTAAGGESAL

MAP2

1501

P11137
LSEKASGSTLRGCTE

ZNF839

231

A8K0R7
RETKALGVCKESGSE

ZNF469

2731

Q96JG9
SECGKAFGEKSSLAT

ZNF84

546

P51523
TSPGTGVRKKTCSFR

TRPM1

1291

Q7Z4N2
KECGKSFSRASSILN

ZNF225

571

Q9UK10
KAVFGRSVSTGKLSD

ULK2

661

Q8IYT8
EECGKAFSRSSTLTK

ZNF91

801

Q05481
TGCSATFSVLKKRRS

ZFYVE27

351

Q5T4F4
EECGKGFSTFSILTK

ZNF208

976

O43345
RKCGKAFSSGSELIR

ZNF140

276

P52738
EECGKAFKRSSTLTK

ZNF493

336

Q6ZR52
KFNSKSKGRREGSCG

ZNRF3

266

Q9ULT6
TRGRTCNKTSKAIDG

WNT4

291

P56705
KECGKSFSRRSGLFI

ZNF354A

301

O60765
GCTGLGKSISFDTKL

ZNF23

141

P17027
KECGKSFSSGSALNR

ZNF345

401

Q14585
KECGKSFSRRSGLFI

ZNF354B

301

Q96LW1
DKCGKGFTRSSSLLI

ZNF239

266

Q16600
KLATCSKDLSGFSNG

TRANK1

306

O15050
RDCGKAFSGKSTLIK

ZNF674

556

Q2M3X9
GTKRGSDELFSTCVT

PTBP1

11

P26599
KGGRFTKAQDCASSF

ATP6AP1L

131

Q52LC2
RLGTSGTAKKTAECI

PPP1R1A

126

Q13522
KECGKSFTFRSGLIG

ZNF850

396

A8MQ14
KECGKSFTFRSGLIG

ZNF850

536

A8MQ14
GSLGTAGRVCSKTSK

WNT2B

316

Q93097
SGLDKSLGASCKDSI

SPOCK2

236

Q92563
KGCGKAFRVSSSLIN

ZNF836

221

Q6ZNA1
KECGKSFSQRGSLAV

ZNF32

136

P17041
KECGKAFSRSTYLGI

ZNF670

256

Q9BS34
GSFGICVVKDDTKIS

ZNF541

1036

Q9H0D2
KLCGKTFSFSSSLRE

ZNF14

506

P17017
VKCGKAFAISSNLSG

ZNF266

411

Q14584
CKLVTIGSGKVFAST

GRIN2B

746

Q13224