Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsnoRNA binding

NOP56 NOP10 PRKDC

8.37e-0534503GO:0030515
HumanPhenoThick eyebrow

FRMD4A ANKRD11 SMARCC2 CHD1 DPF2 MAP3K7 MEF2C

3.29e-06154237HP:0000574
HumanPhenoAbnormal finger morphology

XYLT1 GJA1 ZNF668 FAM13A RASA2 KIF21A PRIM1 SVIL ANKRD11 SMARCC2 CHD1 NOP10 PRKDC DPF2 MAP3K7 MEF2C RPL18

3.93e-0613852317HP:0001167
HumanPhenoRegional abnormality of skin

XYLT1 FLG GJA1 DST RASA2 KIF21A ANKRD11 CHD1 NOP10 MAP3K7 MEF2C

7.19e-065412311HP:0011356
HumanPhenoAbnormal location of ears

XYLT1 GJA1 FRMD4A DST RASA2 KIF21A PRIM1 GLIS3 ANKRD11 PRKDC DPF2 MAP3K7 MEF2C RPL18

8.03e-069452314HP:0000357
HumanPhenoAbnormal eyelid morphology

XYLT1 GJA1 FRMD4A RASA2 KIF21A PRIM1 GLIS3 ANKRD11 SMARCC2 CHD1 NOP10 APOB DPF2 MAP3K7 MEF2C RPL18

3.34e-0514082316HP:0000492
HumanPhenoLow anterior hairline

FRMD4A ANKRD11 SMARCC2 DPF2 MAP3K7 RPL18

3.51e-05147236HP:0000294
HumanPhenoAbnormal skin morphology of the palm

XYLT1 FLG GJA1 DST KIF21A ANKRD11 NOP10 MAP3K7 MEF2C

4.06e-05413239HP:0040211
HumanPhenoAbnormality of the scalp hair

GJA1 FRMD4A RASA2 ANKRD11 SMARCC2 NOP10 DPF2 MAP3K7 RPL18

5.91e-05433239HP:0100037
HumanPhenoAbnormal pinna morphology

XYLT1 GJA1 FRMD4A ZNF668 DST RASA2 KIF21A PRIM1 GLIS3 ANKRD11 PRKDC DPF2 MAP3K7 MEF2C RPL18

6.71e-0512992315HP:0000377
HumanPhenoAbnormal scalp morphology

GJA1 FRMD4A RASA2 ANKRD11 SMARCC2 NOP10 DPF2 MAP3K7 RPL18

8.02e-05450239HP:0001965
HumanPhenoAbnormality of the outer ear

XYLT1 GJA1 FRMD4A ZNF668 DST RASA2 KIF21A PRIM1 GLIS3 ANKRD11 PRKDC DPF2 MAP3K7 MEF2C RPL18

9.64e-0513372315HP:0000356
HumanPhenoDepressed nasal bridge

XYLT1 GJA1 KIF21A PRIM1 GLIS3 SMARCC2 DPF2 MAP3K7 MEF2C RPL18

1.54e-046122310HP:0005280
HumanPhenoFlattened nasal bridge

XYLT1 GJA1 KIF21A PRIM1 GLIS3 SMARCC2 DPF2 MAP3K7 MEF2C RPL18

1.54e-046122310HP:0000425
HumanPhenoThick vermilion border

XYLT1 FRMD4A RASA2 PRIM1 ANKRD11 SMARCC2 DPF2

1.57e-04279237HP:0012471
HumanPhenoAbnormal eyelash morphology

XYLT1 GJA1 FRMD4A SMARCC2 CHD1 NOP10 DPF2

1.76e-04284237HP:0000499
HumanPhenoAbnormality of the hairline

FRMD4A RASA2 ANKRD11 SMARCC2 DPF2 MAP3K7 RPL18

2.18e-04294237HP:0009553
HumanPhenoAbnormal hand morphology

XYLT1 GJA1 DST RASA2 KIF21A PRIM1 ANKRD11 SMARCC2 PRKDC DPF2 MAP3K7 MEF2C RPL18

2.23e-0410822313HP:0005922
HumanPhenoShort chin

DST PRKDC MAP3K7 MEF2C

2.25e-0469234HP:0000331
HumanPhenoAbnormal palm morphology

XYLT1 FLG GJA1 DST KIF21A ANKRD11 NOP10 MAP3K7 MEF2C

2.51e-04521239HP:0100871
HumanPhenoAbnormal cardiac septum morphology

XYLT1 GJA1 ZNF668 DST RASA2 PRIM1 ANKRD11 SMARCC2 DPF2 MAP3K7 RPL18

2.53e-047872311HP:0001671
HumanPhenoAbnormality of the chin

GJA1 DST SVIL ANKRD11 CHD1 PRKDC MAP3K7 MEF2C

2.69e-04409238HP:0000306
HumanPhenoAbnormality of the frontal hairline

FRMD4A ANKRD11 SMARCC2 DPF2 MAP3K7 RPL18

2.91e-04215236HP:0000599
HumanPhenoHirsutism

XYLT1 GJA1 FRMD4A SMARCC2 DPF2 MAP3K7

2.98e-04216236HP:0001007
HumanPhenoAplasia/hypoplasia involving bones of the hand

XYLT1 GJA1 KIF21A PRIM1 ANKRD11 SMARCC2 DPF2 MAP3K7 RPL18

3.20e-04538239HP:0005927
HumanPhenoAbnormal eyebrow morphology

XYLT1 GJA1 FRMD4A ANKRD11 SMARCC2 CHD1 NOP10 DPF2 MAP3K7 MEF2C

3.47e-046742310HP:0000534
HumanPhenoCongenital abnormal hair pattern

FRMD4A RASA2 ANKRD11 SMARCC2 DPF2 MAP3K7 RPL18

4.21e-04327237HP:0011361
HumanPhenoAplasia/hypoplasia involving bones of the upper limbs

XYLT1 GJA1 KIF21A PRIM1 ANKRD11 SMARCC2 DPF2 MAP3K7 RPL18

5.10e-04572239HP:0006496
HumanPhenoClinodactyly

XYLT1 GJA1 ZNF668 RASA2 ANKRD11 SMARCC2 DPF2 MAP3K7 MEF2C

5.23e-04574239HP:0030084
HumanPhenoAbnormal nasal bridge morphology

XYLT1 GJA1 KIF21A PRIM1 GLIS3 ANKRD11 SMARCC2 PRKDC DPF2 MAP3K7 MEF2C RPL18

6.37e-0410292312HP:0000422
HumanPhenoAbnormality of the philtrum

XYLT1 GJA1 PRIM1 GLIS3 ANKRD11 SMARCC2 PRKDC DPF2 MAP3K7 MEF2C

6.40e-047262310HP:0000288
HumanPhenoPostnatal growth retardation

XYLT1 RASA2 PRIM1 SMARCC2 CHD1 DPF2

7.75e-04258236HP:0008897
DomainCH

DST CLMN ARHGEF6

5.85e-0465473SM00033
DomainCH

DST CLMN ARHGEF6

7.26e-0470473PF00307
Domain-

DST CLMN ARHGEF6

7.57e-04714731.10.418.10
DomainCH

DST CLMN ARHGEF6

8.21e-0473473PS50021
DomainCH-domain

DST CLMN ARHGEF6

8.88e-0475473IPR001715
DomainRho_GTPase_activation_prot

ARHGAP5 FAM13A RASA2

1.41e-0388473IPR008936
DomainActinin_actin-bd_CS

DST CLMN

1.52e-0323472IPR001589
DomainACTININ_2

DST CLMN

1.52e-0323472PS00020
DomainACTININ_1

DST CLMN

1.52e-0323472PS00019
DomainChromo/shadow_dom

SMARCC2 CHD1

3.11e-0333472IPR000953
DomainCHROMO

SMARCC2 CHD1

3.11e-0333472SM00298
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ZNF668 TMA16 DST NOP56 OSBPL3 C16orf87 ANKRD11 NOP10 PRKDC ZCCHC7 NOL8 RPL18

2.19e-071294501230804502
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLG TMA16 DST KHDRBS3 NOP56 CDK12 SMARCC2 PRKDC DPF2 ARHGEF6 RPL18

3.09e-071082501138697112
Pubmed

MAP3K7 Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of CHD1.

CHD1 MAP3K7

2.03e-06250233846123
Pubmed

Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer.

CHD1 MAP3K7

2.03e-06250225770290
Pubmed

Identification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functions.

GLIS3 GLIS1

2.03e-06250212042312
Pubmed

Leydig cell function in mice lacking connexin43.

GJA1 PRKDC

2.03e-06250217008472
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

ARHGAP5 NOP56 OSBPL3 SMARCC2 CHD1 NOP10 PRKDC NOL8 RPL18

2.96e-0684750935850772
Pubmed

The functional interactome landscape of the human histone deacetylase family.

NOP56 C16orf87 SVIL ANKRD11 PRKDC MEF2C

3.65e-0628950623752268
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

FLG ZNF668 CLMN OSBPL3 SVIL DPF2 MEF2C NOL8

5.87e-0668950836543142
Pubmed

Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells.

PRKDC ARHGEF6

6.07e-06350219918261
Pubmed

GLIS3, a novel member of the GLIS subfamily of Krüppel-like zinc finger proteins with repressor and activation functions.

GLIS3 GLIS1

6.07e-06350214500813
Pubmed

Gene of the month: GLIS1-3.

GLIS3 GLIS1

6.07e-06350232699115
Pubmed

Interplay between paracrine signaling and gap junctional communication in ovarian follicles.

GJA1 PRKDC

6.07e-06350215585573
Pubmed

Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1).

GLIS3 GLIS1

6.07e-06350218263616
Pubmed

The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and Angiogenesis.

FLG DST

6.07e-06350231425296
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

DST NOP56 CDK12 CLMN SENP6 CHD1 PRKDC NOL8 RPL18

6.52e-0693450933916271
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NOP56 CDK12 ANKRD11 SENP6 SMARCC2 CHD1 PRKDC ZCCHC7 NOL8

7.73e-0695450936373674
Pubmed

Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.

PRKDC MAP3K7

1.21e-05450225189770
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FAM13A CDK12 SVIL SENP6 SMARCC2 PRKDC DPF2 ARHGEF6

1.36e-0577450815302935
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DST NOP56 RASA2 KIF21A LTN1 SMARCC2 CHD1 PRKDC DPF2 RPL18

1.91e-051353501029467282
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

ARHGAP5 TMA16 KHDRBS3 NOP56 CDK12 OSBPL3 SVIL SMARCC2 NOP10 APOB

2.14e-051371501036244648
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

FLG TMA16 NOP56 SMARCC2 CHD1 PRKDC RPL18

2.33e-0560150733658012
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

TMA16 NOP56 SMARCC2 CHD1 PRKDC DPF2

2.69e-0541150635182466
Pubmed

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.

CIR1 MAP3K7

3.03e-0565023031469
Pubmed

Proteomic characterization of the human sperm nucleus.

SEMG2 FLG TMA16 DST MAP3K7 RPL18

3.83e-0543850621630459
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

SEMG2 NOP56 SVIL SMARCC2 APOB PRKDC RPL18

3.91e-0565250731180492
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

ZNF668 TMA16 CDK12 ANKRD11 NOP10

4.25e-0526950529511261
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

TMA16 DST NOP56 OSBPL3 SVIL APOB PRKDC RPL18

5.80e-0594950836574265
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

NOP56 CHD1 NOP10 PRKDC NOL8 RPL18

6.59e-0548350636912080
Pubmed

Coffin-Siris Syndrome

SMARCC2 DPF2

7.25e-05950223556151
Pubmed

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.

FRMD4A SVIL MEF2C

9.03e-056050319075228
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

NOP56 NOP10 MAP3K7 ARHGEF6 RPL18

9.23e-0531750517620599
Pubmed

Increased susceptibility of HIF-1α heterozygous-null mice to cardiovascular malformations associated with maternal diabetes.

GJA1 MEF2C

1.10e-041150223619295
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

SMARCC2 DPF2 MEF2C

1.15e-046550326655900
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

FRMD4A SVIL SMARCC2

1.26e-046750329254152
Pubmed

Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart.

GJA1 MEF2C

1.32e-041250217482496
Pubmed

Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart.

GJA1 MEF2C

1.32e-041250217050624
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ARHGAP5 NOP56 RASA2 CLMN OSBPL3 LTN1 APOB ARHGEF6

1.46e-04108450811544199
Pubmed

Genome-wide association of lipid-lowering response to statins in combined study populations.

CLMN APOB GLIS1

1.55e-047250320339536
Pubmed

Neurogenin3 cooperates with Foxa2 to autoactivate its own expression.

GLIS3 NKX6-1

1.56e-041350223471965
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

CDK12 OSBPL3 SVIL NOP10 RPL18

1.69e-0436150530344098
Pubmed

The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells.

GLIS3 NKX6-1

1.82e-041450227270601
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FLG DST KHDRBS3 NOP56 KIF21A SMARCC2 APOB PRKDC RPL18

1.90e-04144250935575683
Pubmed

Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication.

PRIM1 PRKDC

2.10e-041550212393188
Pubmed

Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.

GJA1 MEF2C

2.10e-041550219782130
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

BCLAF3 NOP56 SVIL SMARCC2 NOP10 PRKDC IDE DPF2

2.25e-04115550820360068
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

SMARCC2 PRKDC IDE DPF2 RPL18

2.66e-0439850535016035
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

NOP56 OSBPL3 SVIL NOP10 PRKDC RPL18

2.69e-0462650633644029
Pubmed

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.

TMA16 NOP56 NOP10 RPL18

2.86e-0422050431822558
Pubmed

A protein interaction landscape of breast cancer.

DST NOP56 SVIL SMARCC2 DPF2 RPL18

2.88e-0463450634591612
Pubmed

A physical interaction network of dengue virus and human proteins.

DST APOB

3.05e-041850221911577
Pubmed

Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain.

NKX6-1 EVX2

3.05e-041850212874134
Pubmed

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis.

FLG NOL8

3.05e-041850232924931
Pubmed

Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium.

GJA1 ARHGEF6

3.05e-041850225139745
Pubmed

Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region.

SMARCC2 DPF2

3.05e-041850216217013
Pubmed

All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3.

NKX6-1 EVX2

3.05e-041850214723851
Pubmed

A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord.

NKX6-1 EVX2

3.05e-041850212435628
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

ARHGAP5 FAM13A NOP56 SMARCC2 CHD1 MAP3K7 ARHGEF6

3.20e-0491650732203420
Pubmed

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

ARHGAP5 TMA16 CDK12 ZCCHC7 RPL18

3.29e-0441750536537216
Pubmed

Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.

SMARCC2 DPF2

3.41e-041950225066234
Pubmed

BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.

SMARCC2 DPF2

3.41e-041950218809673
Pubmed

Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification.

NKX6-1 EVX2

3.41e-041950211567614
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

ZNF668 NOP56 CIR1 CHD1 PRKDC RPL18

3.43e-0465550635819319
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

TMA16 DST NOP56 PRIM1 SVIL PRKDC NOL8 RPL18

3.96e-04125750836526897
Pubmed

The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinoma.

FLG APOB IDE

4.10e-0410050321800051
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

ZNF668 TMA16 NOP56 CDK12 NOP10 RPL18

4.11e-0467850630209976
Pubmed

Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.

SMARCC2 DPF2

4.18e-042150220460684
Pubmed

The deubiquitinase USP36 promotes snoRNP group SUMOylation and is essential for ribosome biogenesis.

NOP56 NOP10

4.18e-042150233852194
Pubmed

Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart.

GJA1 MEF2C

4.18e-042150229444209
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DST LTN1 SENP6

4.22e-041015039872452
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NYAP2 DST NOP56 OSBPL3 KIF21A SVIL SMARCC2

4.32e-0496350728671696
Pubmed

The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.

CDK12 NOP10 PRKDC

4.60e-0410450331365120
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

NOP56 LTN1 SMARCC2 CHD1

4.63e-0425050433536335
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

TMA16 NOP56 CDK12 PRKDC

4.70e-0425150431076518
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

OSBPL3 SVIL PRKDC ARHGEF6

4.99e-0425550415324660
Pubmed

Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression.

GLIS3 NKX6-1

5.03e-042350219805515
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

SMARCC2 DPF2

5.03e-042350230962207
Pubmed

Diversity and specialization of mammalian SWI/SNF complexes.

SMARCC2 DPF2

5.03e-04235028804307
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

TMA16 NOP56 SMARCC2 CHD1 PRKDC NOL8 RPL18

5.06e-0498950736424410
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

TMA16 NOP56 CDK12 LTN1 NOP10 RPL18

5.36e-0471350629802200
Pubmed

Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.

GJA1 GLIS3 MEF2C

5.41e-0411050337219487
Pubmed

Regulation of mesenchymal-to-epithelial transition by PARAXIS during somitogenesis.

FRMD4A ARHGEF6

5.48e-042450224038871
Pubmed

SWI/SNF chromatin remodeling and cancer.

SMARCC2 DPF2

5.48e-042450211790558
Pubmed

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.

SMARCC2 DPF2

5.48e-042450210078207
Pubmed

The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.

SMARCC2 DPF2

5.48e-042450212215535
Pubmed

CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.

SVIL ANKRD11 PRKDC MAP3K7 RPL18

5.56e-0446850536042349
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

DST KHDRBS3 NOP56 SMARCC2 NOL8 RPL18

5.77e-0472350634133714
Pubmed

Chromatin regulation by Brg1 underlies heart muscle development and disease.

GJA1 MEF2C

5.95e-042550220596014
Pubmed

The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.

GLIS3 NKX6-1

5.95e-042550221786021
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

SEMG2 GJA1 FRMD4A NOP56 IDE MEF2C

6.16e-0473250634732716
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

DST NOP56 SVIL SMARCC2 CHD1 PRKDC RPL18

6.22e-04102450724711643
Pubmed

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.

SMARCC2 DPF2

6.44e-042650210778858
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

SVIL CHD1 PRKDC

6.64e-0411850327377895
Pubmed

Shwachman-Bodian Diamond syndrome is a multi-functional protein implicated in cellular stress responses.

PRKDC RPL18

6.95e-042750219602484
Pubmed

Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.

SMARCC2 DPF2

6.95e-042750229374058
Pubmed

Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression.

NKX6-1 EVX2

6.95e-042750220081190
Pubmed

Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease.

PRKDC RPL18

6.95e-042750236266428
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

TMA16 KHDRBS3 NOP56 CHD1 APOB

7.22e-0449650531343991
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

DST NOP56 CDK12 KIF21A SVIL

7.35e-0449850536634849
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

ZNF668 NOP56 CDK12 PRKDC NOL8 RPL18

7.44e-0475950635915203
InteractionARRB2 interactions

NOP56 RASA2 ANKRD11 SMARCC2 NOP10 MAP3K7 ARHGEF6 RPL18

1.25e-05454498int:ARRB2
InteractionNOL8 interactions

DST NOP56 KIF21A NOL8 RPL18

1.46e-05128495int:NOL8
Cytoband2q36.3

NYAP2 FBXO36

2.54e-04224922q36.3
Cytoband2q31.1

CIR1 EVX2

3.68e-03844922q31.1
CytobandEnsembl 112 genes in cytogenetic band chr2q36

NYAP2 FBXO36

3.77e-0385492chr2q36
CytobandEnsembl 112 genes in cytogenetic band chr6q14

MEI4 SENP6

4.87e-0397492chr6q14
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP5 FAM13A

3.75e-0350332721
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASA2 OSBPL3 ARHGEF6

6.18e-03206333682
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

BCLAF3 XYLT1 ARHGAP5 FRMD4A TMA16 KHDRBS3 NOP56 KIF21A PRIM1 CHD1 PWWP3B MAP3K7 NOL8

2.84e-0612574813facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

BCLAF3 XYLT1 ARHGAP5 FRMD4A TMA16 KHDRBS3 NOP56 KIF21A PRIM1 CHD1 PWWP3B MAP3K7 NOL8

1.44e-0514594813facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

BCLAF3 ARHGAP5 FRMD4A ZNF668 TMA16 NOP56 KIF21A PRIM1 SMARCC2 CHD1 PWWP3B MAP3K7

1.61e-0512524812facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasfacebase_RNAseq_e8.5_FloorPlate_2500_K3

GJA1 ARHGAP5 ZNF668 TMA16 NOP56 KIF21A PRIM1 GLIS3 SENP6 CHD1 IDE NOL8

3.96e-0513714812facebase_RNAseq_e8.5_FloorPlate_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

DST CDK12 ANKRD11 CIR1 CHD1 PRKDC NOL8

8.25e-05469487Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

CDK12 C16orf87 KIF21A ANKRD11 CHD1 PRKDC NOL8

1.80e-04532487Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_OlfacPit_2500_K0

BCLAF3 ZNF668 TMA16 ZBTB7C KHDRBS3 NOP56 KIF21A GLIS3 IDE

1.99e-04926489facebase_RNAseq_e10.5_OlfacPit_2500_K0
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1

DST CDK12 KIF21A ANKRD11 PRKDC

2.90e-04259485Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500

BCLAF3 NOP56 GLIS3 PRKDC IDE NOL8

2.93e-04406486gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000

BCLAF3 TMA16 NOP56 PRIM1 GLIS3 PRKDC IDE NOL8

3.31e-04781488gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 CDK12 KIF21A ANKRD11 SENP6 CHD1

5.21e-08188486d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GJA1 DST KHDRBS3 SVIL GLIS3

1.83e-061894858c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GJA1 DST KHDRBS3 SVIL GLIS3

1.83e-061894855d902a4660a27548764bf04c6de152b565da835c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 RASA2 ANKRD11 SENP6 APOB

1.93e-0619148560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 RASA2 ANKRD11 SENP6 APOB

1.93e-0619148509db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 RASA2 ANKRD11 SENP6 APOB

1.93e-06191485973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 CDK12 ANKRD11 SENP6 CHD1

2.09e-06194485e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST KIF21A ANKRD11 NKX6-1 ZCCHC7

2.14e-061954853e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST KIF21A ANKRD11 NKX6-1 ZCCHC7

2.14e-061954857796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NYAP2 ZBTB7C KHDRBS3 CLMN

3.68e-05174484b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NYAP2 ZBTB7C CLMN GLIS3

3.85e-0517648440993c41c1017b53039a337174fc56632b278609
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 CDK12 ANKRD11 CHD1

4.02e-0517848401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD11 CHD1 ZCCHC7 MEF2C

4.58e-051844841154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMD4A ZBTB7C MEF2C GLIS1

4.77e-05186484a95744b8649096bd7cfc3591a02841fa411085b3
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 CDK12 ANKRD11 CHD1

4.87e-05187484663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellControl-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

XYLT1 ANKRD11 CHD1 MEF2C

4.98e-0518848447126c371a242c937499fd278a74a882df8f759c
ToppCellIPF-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

FRMD4A DST ZBTB7C SVIL

5.18e-051904842592765016f291565697265800a232b2edef3792
ToppCellCOPD-Myeloid-Macrophage_Alveolar|COPD / Disease state, Lineage and Cell class

FRMD4A DST SVIL NOP10

5.18e-05190484006e31606d637033bc81333816ee332773d36b08
ToppCellCOPD-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

FRMD4A DST SVIL NOP10

5.18e-051904849fc763d65470ba8858b973689c4d4358faab7dd3
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

FRMD4A DST ZBTB7C SVIL

5.29e-05191484a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellControl-Myeloid-cMonocyte|Control / Disease state, Lineage and Cell class

XYLT1 ANKRD11 CHD1 MEF2C

5.40e-05192484ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLMN OSBPL3 SVIL GLIS3

5.51e-0519348480e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLMN OSBPL3 SVIL GLIS3

5.51e-05193484b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellLA|World / Chamber and Cluster_Paper

XYLT1 FRMD4A ZBTB7C GLIS3

5.51e-05193484d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLMN OSBPL3 SVIL GLIS3

5.51e-05193484263d185af6ed80e639f864e4966268e0862c61dc
ToppCellIPF-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

FRMD4A DST SVIL NOP10

5.51e-0519348403a43b6d235fd47488a6a61efc311a34b232c0f4
ToppCellControl-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

XYLT1 ANKRD11 CHD1 MEF2C

5.62e-05194484f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DST CLMN SVIL GLIS3

5.73e-05195484938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMD4A DST KIF21A MEF2C

5.73e-051954849fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DST CLMN SVIL GLIS3

5.73e-05195484d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellFibroblasts-Pericytes|Fibroblasts / lung cells shred on cell class, cell subclass, sample id

FRMD4A CLMN SVIL MEF2C

5.73e-05195484c2ebc0b33bda9b35b9ef26d69e5d2c6acfdb6ff1
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 DST KHDRBS3 MEF2C

5.73e-05195484a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMD4A DST KIF21A MEF2C

5.85e-051964849afd0a7135028a446f06bb68f334e79b8f171b45
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

CLMN OSBPL3 FBXO36 MEF2C

5.97e-0519748498f0184a09563a544f0c2d4df22c9db2fbc95019
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMD4A DST KIF21A MEF2C

6.08e-05198484c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

NYAP2 DST MEF2C RPL18

6.20e-051994841b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

NYAP2 DST MEF2C RPL18

6.20e-051994844bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMD4A DST KIF21A MEF2C

6.20e-051994848d13a9ea87f685b5a34b84c4571db6be753cf2d9
ToppCellMyeloid-Myeloid-A_(Macrophage-Dendritic)|Myeloid / shred on cell class and cell subclass (v4)

NOP10 MEF2C RPL18

3.79e-0413148397450a8dad22161acb2b41d66ecaec37d530632d
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FRMD4A DST ANKRD11

4.14e-04135483b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellmetastatic_Brain-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

LTN1 FBXO36 GLIS1

5.31e-041474834f7a0c287721befeffabf95b8c5f9ff64149c7c1
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEI4 NOP56 PRIM1

5.63e-04150483d6b977dd47aa017f6ba762f0c505cd896caa523f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MEI4 NYAP2 ARHGEF6

5.85e-04152483fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CIR1 SMARCC2 DPF2

5.96e-0415348388ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CIR1 SMARCC2 DPF2

5.96e-04153483553dff9688a1996d8f4ba16e60c683593d781389
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

XYLT1 DST CCDC183

6.19e-04155483d76a0f99ec35560d18820f9c92b69364ef2250e3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 FRMD4A ZBTB7C

6.31e-04156483abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 FRMD4A ZBTB7C

6.31e-04156483dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellMyeloid-Myeloid-F|Myeloid / shred on cell class and cell subclass (v4)

ZNF668 TMA16 OSBPL3

6.31e-04156483d6317843ae5c5749452889e768c187a9d9e8c7fe
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CIR1 SENP6 APOB

6.31e-04156483f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GJA1 SVIL PWWP3B

6.79e-041604838624f101828efd32cdd38a65df8d94d690720a63
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GJA1 SVIL PWWP3B

6.79e-041604839de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MEI4 NYAP2 ARHGEF6

7.16e-041634838d17f44faf0549fe71a9a45f811f50d767275414
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ZBTB7C CLMN MEF2C

7.42e-04165483f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellCOPD-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

XYLT1 DST SVIL

7.55e-04166483e2cad1db536d5ad5a34c337c19b5e7d1a2851552
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEI4 OSBPL3 PRIM1

7.68e-0416748353e32d6687a07f486141df9f4ab998af4c03a507
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GJA1 DST ZBTB7C

7.82e-04168483f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRMD4A DST KHDRBS3

7.82e-0416848388c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellControl-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

XYLT1 DST SVIL

7.82e-04168483d7118d39253ed9790908b850088ebfc5a86f4065
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

GJA1 ARHGAP5 KHDRBS3

7.95e-04169483815474855a70498a74e52f6583113c63b7267a0c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB7C FAM13A GLIS3

7.95e-04169483319cba07263bf41fcbcbfecd117f91b729394241
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLMN OSBPL3 GLIS3

8.09e-041704833174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP5 OSBPL3 PRIM1

8.09e-04170483badbe200e9d5003d23d115955b10b4ea767f6c26
ToppCelldroplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 FRMD4A DST

8.23e-041714834e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NYAP2 ZBTB7C OSBPL3

8.51e-041734838335b77f730ed43fc348a005566e73a103c6774b
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 MEI4 OSBPL3

8.51e-041734836e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 MEI4 OSBPL3

8.51e-041734834c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

XYLT1 ZNF668 KIF21A

8.51e-0417348323e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NYAP2 ZBTB7C CLMN

8.65e-04174483ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DST KHDRBS3 KIF21A

8.65e-04174483412ccc099028a372b9d953363984c2da54b2187f
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLMN KIF21A APOB

8.80e-041754835c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A ZBTB7C CLMN

8.80e-04175483316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A ZBTB7C CLMN

8.80e-04175483a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellileum-Absorptive_Enterocytes|ileum / shred on tissue and cell subclass

DST APOB

8.90e-0441482650cec538c6acd92f45d804b3c94248c6231aa21
ToppCellCOVID-19-Myeloid-MoAM4|COVID-19 / Condition, Lineage and Cell class

DST FAM13A MEF2C

9.09e-04177483ca5d0c3d5c700bbe4c2da068eb02be6229afb9a0
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GJA1 SVIL GLIS3

9.09e-0417748376f5df101c693e5fa61554244d877fc8169ee66f
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21A GLIS3 APOB

9.09e-041774832bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21A GLIS3 APOB

9.09e-041774839c7c6824b9011363851f084a500d665f025b026e
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

XYLT1 KIF21A MEF2C

9.24e-04178483c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCellmild-Lymphocytic-B_cells_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ZCCHC7 MEF2C RPL18

9.24e-04178483c6fb21401ad802a57e4e4f5a1723c42779fdb33e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ARHGAP5 FBXO36 DPF2

9.39e-041794835be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

FRMD4A ZBTB7C CLMN

9.39e-04179483a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellCOVID-19-kidney-Stressed_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

GJA1 KHDRBS3 MEF2C

9.39e-04179483754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

FRMD4A DST ZBTB7C

9.39e-04179483e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB7C FAM13A GLIS3

9.54e-04180483fd8c2059fcb382ffbfe19e598e37a49e1d5637b5
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP5 TMA16 SVIL

9.54e-04180483a682a5d55c612709c9ee9fa4289d6f8bef7fe1af
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GJA1 FRMD4A MEF2C

9.54e-04180483efc4c5a4dea456527526bbfd88cf70d803893671
ToppCell5'-Adult-LymphNode-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOP56 FBXO36 RPL18

9.54e-04180483cc974ac352ef2adc953fb5f325880e5857595889
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

XYLT1 NYAP2 KIF21A

9.70e-041814837f99002a6411117cc2361334c7c9228e20c574b4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 FRMD4A ZBTB7C

9.70e-041814835f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DST SVIL EVX2

9.70e-04181483beb2771820956be8b190c0088ae3c4efdb53c897
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB7C FAM13A GLIS3

9.70e-0418148357994ff4ecffb15653aee00644d9f887f5e3461d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 FRMD4A ZBTB7C

9.70e-04181483c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

FAM13A SVIL GLIS3

9.70e-04181483c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellfacs-GAT-Fat-3m-Lymphocytic-T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEI4 NYAP2 OSBPL3

9.85e-04182483751bd3e3b49de961523e98197688a05c998c121a
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD1 ZCCHC7 MEF2C

9.85e-04182483eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCellwk_15-18-Epithelial-PNS-SST+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MEI4 NYAP2 KIF21A

9.85e-04182483a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

ZBTB7C GLIS3 PWWP3B

1.00e-0318348300a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCell3'-Adult-SmallIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GJA1 FRMD4A MEF2C

1.00e-03183483f8212bf8a8b8312434ae030261c558c147f61747
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

FRMD4A DST ZBTB7C

1.00e-031834830bcbd60e10b9d6898915dab1987fd46dc7238b19
DiseaseProstatic Neoplasms

GJA1 CDK12 SENP6 CHD1 PRKDC MAP3K7 NOL8

5.85e-05616487C0033578
DiseaseMalignant neoplasm of prostate

GJA1 CDK12 SENP6 CHD1 PRKDC MAP3K7 NOL8

5.85e-05616487C0376358
Diseasecholesterol to total lipids in large HDL percentage

NYAP2 FAM13A APOB

9.99e-0555483EFO_0022234
Diseaseresponse to statin

CLMN APOB GLIS1

1.05e-0456483GO_0036273
DiseaseCoffin-Siris syndrome

SMARCC2 DPF2

2.00e-0413482C0265338
Diseaseleptin measurement, type 2 diabetes mellitus

NYAP2 GLIS3

3.06e-0416482EFO_0005000, MONDO_0005148
Diseasetheta wave measurement

FRMD4A ZBTB7C

3.47e-0417482EFO_0006873
Diseasesunburn

FLG FAM13A ANKRD11

5.19e-0496483EFO_0003958
Diseasetriglyceride measurement, body fat percentage

NYAP2 FAM13A

5.34e-0421482EFO_0004530, EFO_0007800
Diseaseceramide measurement

ZBTB7C CDK12 APOB MAP3K7

5.80e-04235484EFO_0010222
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

GLIS3 IDE GLIS1

6.74e-04105483DOID:9352 (implicated_via_orthology)
Diseasebody fat percentage, high density lipoprotein cholesterol measurement

NYAP2 FAM13A

7.59e-0425482EFO_0004612, EFO_0007800
Diseasealcohol consumption measurement

MEI4 FRMD4A NYAP2 RASA2 CDK12 ANKRD11 SENP6 MAP3K7

8.11e-041242488EFO_0007878
Diseasehematocrit

BCLAF3 FRMD4A NYAP2 FAM13A GLIS3 APOB MEF2C

1.17e-031011487EFO_0004348
Diseaseasphyxia neonatorum

KHDRBS3 ZCCHC7

1.25e-0332482EFO_1000824
Diseasepeak expiratory flow

DST FAM13A SVIL GLIS3 NKX6-1

1.26e-03498485EFO_0009718
Diseasemetastasis measurement, disease progression measurement

CIR1 MAP3K7

1.41e-0334482EFO_0007675, EFO_0008336

Protein segments in the cluster

PeptideGeneStartEntry
DRSKSHRKRETPKSY

CDK12

196

Q9NYV4
HRKRETPKSYKTVDS

CDK12

201

Q9NYV4
HKRKTERKPSEEEYV

ARHGEF6

631

Q15052
PGYLSEKDKKRRESA

ANKRD11

931

Q6UB99
EISSAAESRKKPGHY

EVX2

91

Q03828
RHESSSEKKERKGYS

FLG

151

P20930
SEKKERKGYSPTHRE

FLG

156

P20930
HQGDSYKKSDSRKRP

CHD1

1561

O14646
LDEPHEKYRKKRSSS

RASA2

821

Q15283
SPDDKYSRHRITIKK

NOP10

36

Q9NPE3
ISSDEVKPHYKRKES

LTN1

1101

O94822
DPEEAGHRSGSKKKR

NOP56

546

O00567
DKVTKTYKRRAADPS

DST

7091

Q03001
YRSTKPGEAKETHED

FBXO36

46

Q8NEA4
ATTAYSKPKRGHRKT

MAP3K7

401

O43318
SVGHSPESEDKYRKI

MEF2C

106

Q06413
KQDHATYERKRDDKP

NOL8

951

Q76FK4
SAKPRPHSDEYSKKI

NYAP2

176

Q9P242
SFDETYIKKHGPRRT

NYAP2

206

Q9P242
FEEEKKYRPSHSDKA

FAM13A

686

O94988
VKHRTRDYKKTSLAP

PRIM1

376

P49642
LDEPYEKVKKRSSHS

FRMD4A

616

Q9P2Q2
DKYKAEKSHDELPRT

APOB

3231

P04114
FRKYGHTSKRPKDVE

BCLAF3

211

A2AJT9
HTSKRPKDVERYESR

BCLAF3

216

A2AJT9
GRPKSASAKKHEEER

C16orf87

101

Q6PH81
KRYTDPSSLRKHVKA

GLIS3

481

Q8NEA6
VKDRVKGKSDPYHAT

GJA1

236

P17302
DKIHTKETSEKYRRG

CCDC183

251

Q5T5S1
HKAPSARTAKGVYRD

KHDRBS3

326

O75525
GNHITKSPEDKREYR

IDE

51

P14735
KRYTDPSSLRKHVKA

GLIS1

331

Q8NBF1
GSFESPKKEKRSHRR

OSBPL3

261

Q9H4L5
RSKPADKSSREYTEH

MEI4

21

A8MW99
YTKSRKEPDAVEKRG

SVIL

136

O95425
DSHKESKYAVPRRGS

SVIL

986

O95425
DKDGKRKHTRPTFSG

NKX6-1

231

P78426
SDSPPHKKYRKDEGD

PWWP3B

126

Q5H9M0
RKAHKISYPSSRTEE

SEMG2

281

Q02383
TSKSHGERRPSKYKY

ARHGAP5

1141

Q13017
STPYTKSKRGHREEE

SMARCC2

321

Q8TAQ2
AKRKSTRPHYEEEGE

CLMN

661

Q96JQ2
THKHSPEKRGSERKE

CIR1

361

Q86X95
YKISREHKGDTNPRE

ERVK-25

916

P63136
GYFSHRPKEKVRTDS

XYLT1

136

Q86Y38
KAYKTAPELRSHGRS

ZNF668

91

Q96K58
SHTKPYVRSKGRKFE

RPL18

161

Q07020
LGDKSKRATHVPYRD

KIF21A

311

Q7Z4S6
DYEEDTPKRRGKGKS

DPF2

171

Q92785
KRKHKDTYSTEAPLG

SENP6

1086

Q9GZR1
YSRLPKDDVHAKESK

PRKDC

1881

P78527
KTDHLTEKAYSDTPR

ZBTB7C

191

A1YPR0
YHTSREDKSPKEGKR

ZCCHC7

501

Q8N3Z6
YKISREHKGDTNPRE

ERVK-19

921

Q9WJR5
GREKKVIHPYSRKAA

TMA16

11

Q96EY4