Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	8.75e-28	1459	77	42	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF160 ZNF417 ZNF281 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	5.61e-26	1412	77	40	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF587 ZNF746 INSM1 ZNF316 ZNF816 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF286A ZNF546 ZNF585B KLF2	4.01e-21	1244	77	34	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF587 ZNF746 INSM1 ZNF316 ZNF816 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF286A ZNF546 ZNF585B KLF2	7.91e-21	1271	77	34	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF536 ZBTB33 CTCF ZNF746 INSM1 ZNF202 ZNF281	2.34e-04	320	77	7	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZNF536 ZBTB33 CTCF ZNF746 INSM1 ZNF202 ZNF281	2.62e-04	326	77	7	GO:0001217
GeneOntologyMolecularFunction	chromatin insulator sequence binding	CTCFL CTCF	3.04e-04	7	77	2	GO:0043035
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	CTCFL ZNF600 ZNF473 CTCF OSR2 ZNF808 ZNF227 ZNF585B	1.40e-03	560	77	8	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	CTCFL ZNF600 ZNF473 CTCF OSR2 ZNF808 ZNF227 ZNF585B	1.50e-03	566	77	8	GO:0001216
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	ZNF536 ZBTB33 ZNF473 KDM5A CTCF AASS ZNF746 INSM1 OSR1 TCF25 OSR2 ZNF202 ZNF281 KLF2	2.66e-05	1053	76	14	GO:0000122
GeneOntologyBiologicalProcess	embryonic skeletal limb joint morphogenesis	OSR1 OSR2	4.01e-05	3	76	2	GO:0036023
GeneOntologyBiologicalProcess	positive regulation of embryonic development	RBM19 OSR1 OSR2	1.32e-04	27	76	3	GO:0040019
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	ZNF536 ZBTB33 ZNF473 KDM5A CTCF AASS ZNF746 INSM1 OSR1 TCF25 OSR2 ZNF202 BTAF1 ZNF281 KLF2	1.53e-04	1399	76	15	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	ZNF536 ZBTB33 ZNF473 KDM5A CTCF AASS ZNF746 INSM1 OSR1 TCF25 OSR2 ZNF202 BTAF1 ZNF281 KLF2	1.71e-04	1413	76	15	GO:1902679
Domain	-	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 GTF3A ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	2.40e-43	679	77	44	3.30.160.60
Domain	zf-C2H2	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 GTF3A ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	5.93e-43	693	77	44	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 GTF3A ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	6.32e-43	694	77	44	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 GTF3A ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	8.15e-41	775	77	44	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 GTF3A ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	9.13e-41	777	77	44	PS00028
Domain	Znf_C2H2-like	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 GTF3A ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	2.63e-40	796	77	44	IPR015880
Domain	Znf_C2H2	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 GTF3A ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	4.31e-40	805	77	44	IPR007087
Domain	ZnF_C2H2	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 GTF3A ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 INSM1 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	5.07e-40	808	77	44	SM00355
Domain	zf-C2H2_6	ZNF823 ZNF419 ZNF490 ZNF600 ZNF320 ZNF560 ZNF473 ZSCAN22 ZNF607 ZNF587 ZNF746 ZNF316 OSR1 ZNF816 OSR2 ZNF808 ZNF761 ZNF227 ZNF160 ZNF417 ZNF865 ZNF501 ZNF416 ZNF548 ZNF582 ZNF286A ZNF546	8.26e-29	314	77	27	PF13912
Domain	KRAB	ZNF823 ZNF419 ZNF490 ZNF320 ZNF560 ZNF473 ZNF607 ZNF674 ZNF587 ZNF746 ZNF316 ZNF816 ZNF202 ZNF74 ZNF808 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF416 ZNF548 ZNF582 ZNF286A ZNF546 ZNF585B	8.57e-26	358	77	26	PS50805
Domain	KRAB	ZNF823 ZNF419 ZNF490 ZNF320 ZNF560 ZNF473 ZNF607 ZNF674 ZNF587 ZNF746 ZNF316 ZNF816 ZNF202 ZNF74 ZNF808 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF416 ZNF548 ZNF582 ZNF286A ZNF546 ZNF585B	8.57e-26	358	77	26	PF01352
Domain	KRAB	ZNF823 ZNF419 ZNF490 ZNF320 ZNF560 ZNF473 ZNF607 ZNF674 ZNF587 ZNF746 ZNF316 ZNF816 ZNF202 ZNF74 ZNF808 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF416 ZNF548 ZNF582 ZNF286A ZNF546 ZNF585B	1.88e-25	369	77	26	SM00349
Domain	KRAB	ZNF823 ZNF419 ZNF490 ZNF320 ZNF560 ZNF473 ZNF607 ZNF674 ZNF587 ZNF746 ZNF316 ZNF816 ZNF202 ZNF74 ZNF808 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF416 ZNF548 ZNF582 ZNF286A ZNF546 ZNF585B	2.02e-25	370	77	26	IPR001909
Domain	SCAN	ZSCAN22 ZNF165 ZNF202	1.60e-03	56	77	3	SM00431
Domain	SCAN_BOX	ZSCAN22 ZNF165 ZNF202	1.77e-03	58	77	3	PS50804
Domain	SCAN	ZSCAN22 ZNF165 ZNF202	1.77e-03	58	77	3	PF02023
Domain	SCAN_dom	ZSCAN22 ZNF165 ZNF202	1.77e-03	58	77	3	IPR003309
Domain	Retrov_capsid_C	ZSCAN22 ZNF165 ZNF202	1.86e-03	59	77	3	IPR008916
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF419 ZNF490 ZNF600 ZNF320 ZNF560 ZNF473 ZNF607 ZNF587 ZNF746 ZNF70 ZNF202 ZNF74 PIP4K2B ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF416 ZNF548 ZNF582 ZNF286A ZNF546 ZNF585B	1.44e-10	1387	61	25	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZNF823 ZNF419 ZNF490 ZNF473 CTCF ZNF746 ZNF202 ZNF808 PIP4K2B ZNF740 ZNF160 ZNF416 ZNF286A ZNF585B	3.71e-06	768	61	14	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	ZNF823 ZNF419 ZNF490 GTF3A ZNF473 CTCF ZNF746 ZNF202 ZNF808 PIP4K2B ZNF740 ZNF160 ZNF416 ZNF286A ZNF585B	2.16e-05	1022	61	15	MM15436
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF419 ZNF490 ZNF320 ZNF607 ZNF587 ZNF316 ZNF74 ZNF227 ZNF160 ZNF417	9.21e-12	181	77	10	37372979
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF320 DCAF13 ZBTB33 ZNF473 CTCF PHF3 ZNF316 ZNF70 ZNF808 ZNF740 ZNF227 ZNF160 ZNF417 ZNF281 ZNF286A	5.26e-08	1203	77	15	29180619
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF419 ZBTB33 GTF3A ZNF473 KDM5A CTCF OSR1 ZNF202 ZNF740 ZNF160 ZNF286A KLF2	2.10e-07	808	77	12	20412781
Pubmed	The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis.	CTCFL CTCF	4.84e-06	2	77	2	34158481
Pubmed	Discovering a binary CTCF code with a little help from BORIS.	CTCFL CTCF	4.84e-06	2	77	2	29077515
Pubmed	BORIS and CTCF are overexpressed in squamous intraepithelial lesions and cervical cancer.	CTCFL CTCF	4.84e-06	2	77	2	26125810
Pubmed	The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso.	ZBTB33 CTCF	4.84e-06	2	77	2	16230345
Pubmed	Comparative expression pattern of Odd-skipped related genes Osr1 and Osr2 in chick embryonic development.	OSR1 OSR2	4.84e-06	2	77	2	16554187
Pubmed	Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells.	CTCFL CTCF	4.84e-06	2	77	2	28145452
Pubmed	CTCF and CTCFL in cancer.	CTCFL CTCF	4.84e-06	2	77	2	32334335
Pubmed	Zinc-finger transcription factor odd-skipped related 2 is one of the regulators in osteoblast proliferation and bone formation.	OSR1 OSR2	4.84e-06	2	77	2	17547533
Pubmed	The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells.	CTCFL CTCF	4.84e-06	2	77	2	23553099
Pubmed	Osr2, a new mouse gene related to Drosophila odd-skipped, exhibits dynamic expression patterns during craniofacial, limb, and kidney development.	OSR1 OSR2	4.84e-06	2	77	2	11520675
Pubmed	The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer.	CTCFL CTCF	4.84e-06	2	77	2	12191639
Pubmed	BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.	CTCFL CTCF	4.84e-06	2	77	2	12011441
Pubmed	Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation.	CTCFL CTCF	4.84e-06	2	77	2	32393311
Pubmed	The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner.	CTCFL CTCF	4.84e-06	2	77	2	22709888
Pubmed	Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress.	CTCFL CTCF	1.45e-05	3	77	2	33411704
Pubmed	Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage.	CTCFL CTCF	1.45e-05	3	77	2	21296871
Pubmed	Integrating role of T antigen, Rb2/p130, CTCF and BORIS in mediating non-canonical endoplasmic reticulum-dependent death pathways triggered by chronic ER stress in mouse medulloblastoma.	CTCFL CTCF	1.45e-05	3	77	2	22544282
Pubmed	BORIS Expression in Ovarian Cancer Precursor Cells Alters the CTCF Cistrome and Enhances Invasiveness through GALNT14.	CTCFL CTCF	1.45e-05	3	77	2	31292201
Pubmed	Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells.	CTCFL CTCF	1.45e-05	3	77	2	16140944
Pubmed	Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer.	CTCFL CTCF	1.45e-05	3	77	2	25499215
Pubmed	CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer.	CTCFL CTCF	1.45e-05	3	77	2	21325284
Pubmed	Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.	ZSCAN22 ZNF501 ZNF546	1.56e-05	22	77	3	1505991
Pubmed	Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development.	OSR1 OSR2	2.89e-05	4	77	2	19389375
Pubmed	The nephrogenic potential of the transcription factors osr1, osr2, hnf1b, lhx1 and pax8 assessed in Xenopus animal caps.	OSR1 OSR2	2.89e-05	4	77	2	21281489
Pubmed	DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation.	CTCFL CTCF	4.82e-05	5	77	2	18413740
Pubmed	Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2).	ZNF70 ZNF74	7.22e-05	6	77	2	1639391
Pubmed	Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis.	OSR1 OSR2	1.01e-04	7	77	2	15175245
Pubmed	Odd-skipped related-1 controls neural crest chondrogenesis during tongue development.	OSR1 OSR2	1.34e-04	8	77	2	24167250
Pubmed	CTCF regulates the local epigenetic state of ribosomal DNA repeats.	CTCFL CTCF	1.34e-04	8	77	2	21059229
Pubmed	The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation.	OSR1 OSR2	1.34e-04	8	77	2	21262216
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF536 ZBTB33 KDM5A CTCF ZNF316 TCF25 PIP4K2B ZNF740 ZNF281 PGAM5	1.74e-04	1116	77	10	31753913
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZNF536 ZBTB33 GTF3A ZNF746 OSR1 OSR2 ZNF585B KLF2	1.75e-04	709	77	8	22988430
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ZBTB33 OSR1 OSR2 ZNF740 ZNF281 ZNF501 KLF2	2.06e-04	544	77	7	28473536
Pubmed	Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.	CXCR5 CCR3	2.15e-04	10	77	2	10479460
Pubmed	The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation.	CTCFL CTCF	2.15e-04	10	77	2	17048991
Pubmed	Analysis of transcription factors expressed at the anterior mouse limb bud.	OSR1 OSR2	3.71e-04	13	77	2	28467430
Pubmed	Cleft palate defect of Dlx1/2-/- mutant mice is caused by lack of vertical outgrowth in the posterior palate.	OSR1 OSR2	4.33e-04	14	77	2	22972697
Pubmed	Scleraxis-lineage cells are required for correct muscle patterning.	OSR1 OSR2	4.99e-04	15	77	2	37246520
Pubmed	Genome-wide association of lipid-lowering response to statins in combined study populations.	CTCFL CNTNAP5 CLMN	5.58e-04	72	77	3	20339536
Pubmed	MOZ directs the distal-less homeobox gene expression program during craniofacial development.	OSR1 OSR2	6.44e-04	17	77	2	31340933
Pubmed	HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism.	CXCR5 CCR3	6.44e-04	17	77	2	24489825
Pubmed	Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2.	CTCF POLE2 BTAF1	6.78e-04	77	77	3	19505873
Pubmed	DNA replication in eukaryotic cells.	POLE2 MCM6	7.23e-04	18	77	2	12045100
Pubmed	The contribution of de novo coding mutations to autism spectrum disorder.	CTCF PHF3	7.23e-04	18	77	2	25363768
Pubmed	Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.	OSR1 KLF2	7.23e-04	18	77	2	30352852
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF473 MON1B ZNF160 SEPTIN6 ANO8 ZNF286A	7.98e-04	493	77	6	15368895
Pubmed	Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.	OSR1 OSR2	8.07e-04	19	77	2	30385546
Pubmed	Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice.	OSR1 OSR2	8.07e-04	19	77	2	34732852
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF227 ZNF285	8.96e-04	20	77	2	12743021
Pubmed	A census of human transcription factors: function, expression and evolution.	CTCFL ZBTB33 CTCF INSM1 ZNF202 ZNF160 ZNF281 KLF2	8.99e-04	908	77	8	19274049
Pubmed	Next-generation sequencing to generate interactome datasets.	ZNF490 ZNF165 ZNF607 TCF25 MOB3A ZNF417 LILRB5 EDRF1 SEPTIN6	9.66e-04	1147	77	9	21516116
Pubmed	Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.	ZNF227 ZNF160	9.89e-04	21	77	2	7865130
Pubmed	Loss of Tbx3 in murine neural crest reduces enteric glia and causes cleft palate, but does not influence heart development or bowel transit.	OSR1 OSR2	9.89e-04	21	77	2	30292786
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	DCAF13 ZBTB33 CTCF RBM19 ZNF740	1.08e-03	349	77	5	25665578
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	ZSCAN22 ZNF501	1.09e-03	22	77	2	1946370
Pubmed	Osr1 functions downstream of Hedgehog pathway to regulate foregut development.	OSR1 OSR2	1.19e-03	23	77	2	28501478
Pubmed	Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles.	OSR1 OSR2	1.52e-03	26	77	2	29712641
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ZBTB33 CTCF PHF3 ZNF740 ZNF865 PGAM5	1.87e-03	583	77	6	29844126
Pubmed	A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.	CXCR5 OSR1	1.89e-03	29	77	2	37160119
Pubmed	Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.	CXCR5 ZNF536	2.16e-03	31	77	2	27798109
Interaction	TRIM28 interactions	ZNF823 ZNF419 ZNF490 ZNF600 ZNF320 DCAF13 ZBTB33 ZNF607 ZNF674 ZNF587 ZNF746 ZNF316 ZNF816 ZNF74 ZNF808 MCM6 ZNF761 ZNF227 ZNF160 ZNF417 ZNF416 ZNF585B	1.37e-08	1474	76	22	int:TRIM28
Interaction	LTBP2 interactions	ZNF490 ZNF320 ZNF607 ZNF316 ZNF74 ZNF417 ZNF865	3.19e-08	85	76	7	int:LTBP2
Interaction	ZFP37 interactions	CTCFL ZNF473 CTCF ZNF746 ZNF281	1.12e-06	49	76	5	int:ZFP37
Interaction	PRDM4 interactions	CTCFL ZNF536 ZNF473 CTCF ZNF281	1.51e-06	52	76	5	int:PRDM4
Interaction	ZNF667 interactions	CTCFL ZNF473 CTCF ZNF746 ZNF281	1.66e-06	53	76	5	int:ZNF667
Interaction	ZNF287 interactions	CTCFL ZNF473 CTCF ZNF746 ZNF281	3.10e-06	60	76	5	int:ZNF287
Interaction	NOTCH2 interactions	ZNF823 ZNF419 ZNF490 ZNF320 ZBTB33 ZNF746 ZNF316 ZNF761 ZNF417 ZNF865	4.14e-06	423	76	10	int:NOTCH2
Interaction	CEP70 interactions	ZNF490 ZNF165 ZNF607 ZNF587 ZNF202 ZNF227 ZNF417 ZNF491	6.44e-06	262	76	8	int:CEP70
Interaction	ZNF652 interactions	CTCFL ZNF473 CTCF ZNF281	8.95e-06	35	76	4	int:ZNF652
Interaction	ZNF837 interactions	ZNF473 ZNF165 ZNF587 ZNF202 ZNF417	1.21e-05	79	76	5	int:ZNF837
Interaction	TRIM41 interactions	ZNF490 ZNF473 ZNF165 ZNF587 ZNF74 ZNF417 ZNF286A	2.11e-05	223	76	7	int:TRIM41
Interaction	KRTAP10-9 interactions	ZNF490 ZNF473 ZNF165 ZNF587 ZNF417 ZNF491 ZNF286A	3.47e-05	241	76	7	int:KRTAP10-9
Interaction	TEX19 interactions	ZNF490 ZNF746 ZNF316 ZNF865	5.12e-05	54	76	4	int:TEX19
Interaction	ZNF473 interactions	CTCFL ZNF473 CTCF ZNF202	5.91e-05	56	76	4	int:ZNF473
Interaction	RNF4 interactions	ZNF320 DCAF13 ZBTB33 ZNF473 CTCF PHF3 ZNF746 ZNF316 ZNF70 ZNF808 ZNF740 ZNF227 ZNF160 ZNF417 ZNF281 ZNF286A	6.06e-05	1412	76	16	int:RNF4
Interaction	KRTAP10-7 interactions	ZNF419 ZNF490 ZNF320 ZNF165 ZNF587 ZNF417 ZNF491	1.19e-04	293	76	7	int:KRTAP10-7
Interaction	CARD10 interactions	ZNF165 ZNF587 ZNF202 ZNF285 ZNF286A	1.19e-04	127	76	5	int:CARD10
Interaction	ZNF677 interactions	ZNF320 DCAF13 PHF3	1.41e-04	27	76	3	int:ZNF677
Interaction	ZFAT interactions	CTCFL ZNF473 CTCF	1.58e-04	28	76	3	int:ZFAT
Interaction	ZNF423 interactions	CTCFL ZNF473 CTCF ZNF281	1.67e-04	73	76	4	int:ZNF423
Interaction	ZNF710 interactions	CTCFL ZNF473 CTCF	1.94e-04	30	76	3	int:ZNF710
Interaction	ZFP3 interactions	CTCFL ZNF473 CTCF	1.94e-04	30	76	3	int:ZFP3
Interaction	RPL26L1 interactions	ZNF490 AMPD2 ZNF320 CTCF RBM19 ZNF746 ZNF501 ZNF286A	2.17e-04	431	76	8	int:RPL26L1
Interaction	RBAK interactions	CTCFL ZNF473 CTCF ZNF74	2.49e-04	81	76	4	int:RBAK
Interaction	ZNF382 interactions	CTCFL ZNF473 CTCF	2.59e-04	33	76	3	int:ZNF382
Interaction	ZNF513 interactions	CTCFL ZNF473 CTCF	2.84e-04	34	76	3	int:ZNF513
Interaction	FBLN5 interactions	ZNF320 ZBTB33 ZNF746 ZNF74 ZNF865	3.38e-04	159	76	5	int:FBLN5
Interaction	ZFP28 interactions	CTCFL ZNF473 ZNF281	3.65e-04	37	76	3	int:ZFP28
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF419 ZNF600 ZNF320 ZNF473 ZSCAN22 ZNF607 ZNF587 ZNF816 KCNN4 ZNF808 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF416 ZNF548 ZNF582 LILRB5 ZNF546 ZNF585B	2.83e-17	1192	77	22	chr19q13
Cytoband	19q13.43	ZNF419 ZSCAN22 ZNF587 ZNF417 ZNF548 ZNF582	8.27e-09	87	77	6	19q13.43
Cytoband	19q13.41	ZNF600 ZNF320 ZNF816 ZNF808	9.49e-06	78	77	4	19q13.41
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	ZNF823 ZNF490 ZNF560 ZSWIM4 MOB3A ZNF491 ANO8 KLF2	5.84e-05	797	77	8	chr19p13
Cytoband	19p13.2	ZNF823 ZNF490 ZNF560 ZNF491	6.14e-04	229	77	4	19p13.2
Cytoband	19q13.42	ZNF761 ZNF160 ZNF865	1.24e-03	125	77	3	19q13.42
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF823 ZNF419 ZNF490 CTCFL ZNF536 ZNF600 ZNF320 ZBTB33 GTF3A ZNF560 ZNF473 ZSCAN22 ZNF165 ZNF607 CTCF ZNF674 ZNF587 ZNF746 ZNF316 OSR1 ZNF816 ZNF70 OSR2 ZNF202 ZNF74 ZNF808 ZNF740 ZNF761 ZNF227 ZNF285 ZNF160 ZNF417 ZNF865 ZNF281 ZNF501 ZNF416 ZNF548 ZNF582 ZNF491 ZNF286A ZNF546 ZNF585B KLF2	1.72e-43	718	68	43	28
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF607 POLE2 ZNF70 ZNF74 MCM6 CCR3	3.41e-07	159	77	6	c960df9e4fa980401941866b5081facac4590b4d
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|368C / Donor, Lineage, Cell class and subclass (all cells)	ZNF419 ZNF165 ZNF740 ZSWIM4 ORAI2 ZNF582	4.89e-07	169	77	6	0d96c0b4fd26fbc0bf44ff7bed2936eebcc55b74
ToppCell	COVID-CD4-CD4_Treg\|COVID / Condition, Cell_class and T cell subcluster	AMPD2 RBM19 ZNF202 ZNF74 ZNF582	8.33e-06	159	77	5	037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Lymphocytic-B_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCR5 ZNF473 INSM1 KCNN4 SEPTIN6	1.25e-05	173	77	5	a693772987f1baee533dd0bd285a3c7b5619a73b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD2 CTCFL HECW2 OSR2 CCR3	1.32e-05	175	77	5	1b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD2 CTCFL HECW2 OSR2 CCR3	1.32e-05	175	77	5	a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CXCR5 ZNF165 ORAI2 SEPTIN6 KLF2	1.60e-05	182	77	5	5f1f10c845b73d1f69794277925ef847ff23ac2d
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CXCR5 ZNF165 ORAI2 SEPTIN6 KLF2	1.78e-05	186	77	5	1a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CXCR5 ZNF165 ORAI2 SEPTIN6 KLF2	1.78e-05	186	77	5	f1366638edaecad5cad6367440f4c693513bed7e
ToppCell	Bronchus_Control_(B.)-Immune-TX-B_cells\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CXCR5 ZNF165 ORAI2 SEPTIN6 KLF2	2.40e-05	198	77	5	6231c44a909dd06f85c8210814e976a5f29148d0
Disease	COVID-19, mortality	ZNF823 CNTNAP5 ZNF316 CCR3	7.25e-04	170	70	4	EFO_0004352, MONDO_0100096
Disease	Tourette syndrome, schizophrenia	ZNF536 PHF3	8.28e-04	18	70	2	EFO_0004895, MONDO_0005090

Protein segments in the cluster

Peptide	Gene	Start	Entry
LFTYHSVLIRHQRVH	ZNF286A	251	Q9HBT8
IVHAVHAYRHRRLLS	CXCR5	151	P32302
GELVRHRRYKHTHEK	CTCFL	326	Q8NI51
FVTSGELVRHRRYKH	CTCF	331	P49711
YGTVLSRHHHLVRKT	AASS	261	Q9UDR5
SRHHHLVRKTDAVYD	AASS	266	Q9UDR5
DYHLHKVGIVFHSRR	APCDD1L	126	Q8NCL9
RERYTILHQRTHRHE	POLE2	131	P56282
HRDFYNIRKVDTHIH	AMPD2	406	Q01433
RKHRKHIRAYLSFHA	CPA6	311	Q8N4T0
FQHYPHIKRIARHRH	DCAF13	381	Q9NV06
VQVRHHRHTRAYAFF	ANO8	96	Q9HCE9
RKAFRHLAYSKFHHV	RBM19	636	Q9Y4C8
RSHVHHRYIELFLNS	GRSF1	461	Q12849
IHFYRSLVRHKTERH	ORAI2	216	Q96SN7
QRLSDLYHRLHARLH	MON1B	446	Q7L1V2
KVRRDTHHFERYQHN	HECW2	956	Q9P2P5
RIIEKVIHRLTHYDH	MCM6	771	Q14566
YKHTRRKESHAARRH	KCNN4	326	O15554
FFDHVTHRVRLYHIQ	MAN2A1	841	Q16706
YRTKHEIHHTGERRY	ZBTB33	536	Q86T24
HLRKQHRVLADLHYS	EDRF1	1046	Q3B7T1
LSRLFRVFVHVYIHH	MOB3A	156	Q96BX8
RVFVHVYIHHFDRIA	MOB3A	161	Q96BX8
ATRHIFLIRHSQYHV	PGAM5	96	Q96HS1
HRHQSKHRTSAHFYR	LILRB5	481	O75023
HKAFRRQDHLRDHRY	OSR2	206	Q8N2R0
HYRRLRRHCVFSHEE	KDM5A	601	P29375
AFRRQDHLRDHRYIH	OSR1	211	Q8TAX0
DKHHLRHRFYRITTP	MIB1	116	Q86YT6
HHTVTKHRGIITLYR	BTAF1	961	O14981
ERFRKYLRHFFHRHL	CCR3	306	P51677
HKLLHSVRARFVRFV	CNTNAP5	141	Q8WYK1
FRRQAYLRKHLLAHH	INSM1	376	Q01101
RVHEFIFHTRKFITR	PLCZ1	391	Q86YW0
TRNVFSHRLTVHRKY	PIP4K2B	201	P78356
IRRVLHTYHDSRIHV	SEPTIN6	136	Q14141
IYLRRHTHRSSESDH	CLMN	911	Q96JQ2
KTFYHHTSFRRHMIR	ZNF823	311	P16415
AFHFKSILERHRIIH	ZNF761	306	Q86XN6
YNHVSSLIRHRRCHK	ZNF865	261	P0CJ78
VFRHNSYLATHRRIH	ZNF160	321	Q9HCG1
VYIRKSHLERHRRIH	ZNF320	421	A2RRD8
IYFSHLRRHERSHTG	ZNF490	456	Q9ULM2
SFRYRSHLTEHQRLH	ZNF587	416	Q96SQ5
SFRYRSHLTEHQRLH	ZNF417	416	Q8TAU3
FRTSRQLTVHHRFHY	ZNF607	206	Q96SK3
FSYSHKLTIHRRVHT	ZNF607	486	Q96SK3
SFSFHAELARHRRIH	ZNF546	421	Q86UE3
LFRHHRIHTGEKLYE	ZNF585B	201	Q52M93
RHRASLVYHRRLHTL	ZNF808	521	Q8N4W9
RSSYHLRRHVLIHTG	ZNF281	271	Q9Y2X9
QRFYSDSHHLKRERH	PHF3	1921	Q92576
AFNRISHLKVHYRIH	ZNF582	291	Q96NG8
GRAFKRVSHLTVHYR	ZNF582	401	Q96NG8
RTYHQVVVHSRVHKR	ZNF536	641	O15090
SASLKYHLERHHRER	ZNF536	791	O15090
HIAHSEAARLRFRHF	ZSCAN22	41	P10073
RHRSALIEHYKTHTR	ZNF70	401	Q9UC06
HRSRLAKHQRYHAAV	ZNF316	356	A6NFI3
VYKSHLVTHRRIHTG	ZNF316	411	A6NFI3
RRESSHKHTFFHPRV	ZNF416	221	Q9BWM5
TFRVSSHLIRHFRIH	ZNF165	436	P49910
FRYISTLIRHQRIHT	ZNF548	346	Q8NEK5
SFRYHCRLIRHQRVH	ZNF548	401	Q8NEK5
FRHRSRLTYHQKVHT	ZNF227	781	Q86WZ6
FRSAKYIRIHGRTHT	ZNF491	336	Q8N8L2
FSSHAYLIVHRRIHT	ZNF74	481	Q16587
FIRDYHLSRHILTHT	GTF3A	81	Q92664
RFTERSKLIDHYRTH	ZNF746	546	Q6NUN9
YHLIRHEKTHIRQAF	ZNF674	321	Q2M3X9
TIDRRHRAHHPKHVY	PLEKHA5	576	Q9HAU0
RSSYHLKRHILIHTG	ZNF740	111	Q8NDX6
FFRHNSSLFKHRRIH	ZNF419	491	Q96HQ0
TFRLRSYLASHRRVH	ZNF600	506	Q6ZNG1
FSEHRRYLAHRKTHA	ZNF202	546	O95125
LSSRKHVLYVEHRHL	TCF25	171	Q9BQ70
SSYFHLHQRDHIREK	ZNF285	496	Q96NJ3
TFRKQAHLSEHYRIH	ZNF501	226	Q96CX3
RHHITHSREREYKCD	ZNF816	246	Q0VGE8
YIRRSHLERHRKIHT	ZNF816	406	Q0VGE8
FTERSYLTKHLRRHS	ZNF560	581	Q96MR9
LIHHQRIHSRVRLYK	ZNF473	606	Q8WTR7
AHVVALSLYRIRHAH	ZSWIM4	166	Q9H7M6
SDELTRHYRKHTGHR	KLF2	316	Q9Y5W3