Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L RASA1 TBC1D3D RALGAPA2 TBC1D3C TBC1D3B PREX2 ARFGAP2 TBC1D3I TBC1D3G RASAL1 TBC1D3K TBC1D3F	1.21e-12	279	104	16	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L RASA1 TBC1D3D ITSN1 RALGAPA2 TBC1D3C TBC1D3B PREX2 ARFGAP2 ARHGEF4 TBC1D3I TBC1D3G RASAL1 TBC1D3K TBC1D3F	1.26e-10	507	104	18	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L RASA1 TBC1D3D ITSN1 RALGAPA2 TBC1D3C TBC1D3B PREX2 ARFGAP2 ARHGEF4 TBC1D3I TBC1D3G RASAL1 TBC1D3K TBC1D3F	1.26e-10	507	104	18	GO:0030695
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L RASA1 TBC1D3D ITSN1 RALGAPA2 TBC1D3C TBC1D3B PREX2 ARFGAP2 TBC1D3I TBC1D3G CTSL RASAL1 TBC1D3K TBC1D3F	7.50e-09	656	104	18	GO:0008047
GeneOntologyMolecularFunction	molecular function activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L RASA1 TBC1D3D ITSN1 RALGAPA2 TBC1D3C TBC1D3B PREX2 ARFGAP2 EPHA2 TBC1D3I TBC1D3G CTSL RASAL1 TBC1D3K TBC1D3F	1.81e-05	1233	104	19	GO:0140677
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	AXL NTRK3 TYRO3 EPHA2 MERTK	2.24e-05	65	104	5	GO:0004714
GeneOntologyMolecularFunction	enzyme regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L RASA1 TBC1D3D ITSN1 CD109 RALGAPA2 TBC1D3C TBC1D3B PREX2 ARFGAP2 ARHGEF4 TBC1D3I TBC1D3G CTSL RASAL1 TBC1D3K TBC1D3F	3.76e-05	1418	104	20	GO:0030234
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	EP400 CHD4 RAD54B SHPRH	4.02e-05	37	104	4	GO:0140658
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	AXL NTRK3 TYRO3 EPHA2 MERTK	8.20e-05	85	104	5	GO:0019199
GeneOntologyMolecularFunction	solute:inorganic anion antiporter activity	SLC4A1 SLC4A5 SLC25A23	6.10e-04	32	104	3	GO:0005452
GeneOntologyMolecularFunction	protein tyrosine kinase activity	AXL NTRK3 TYRO3 EPHA2 MERTK	9.74e-04	145	104	5	GO:0004713
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D NTRK3 RALGAPA2 TBC1D3C TBC1D3B EPHA2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.61e-16	109	103	14	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D NTRK3 RALGAPA2 TBC1D3C TBC1D3B PREX2 EPHA2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.31e-12	244	103	15	GO:0043547
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D NTRK3 RALGAPA2 TBC1D3C TBC1D3B PREX2 EPHA2 TBC1D3I TBC1D3G RASAL1 TBC1D3K TBC1D3F	1.03e-11	335	103	16	GO:0043087
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D NTRK3 RALGAPA2 TBC1D3C TBC1D3B PREX2 EPHA2 TBC1D3I TBC1D3G CTSL TBC1D3K TBC1D3F	3.52e-09	499	103	16	GO:0051345
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D AXL NTRK3 RALGAPA2 TBC1D3C TBC1D3B PREX2 AXIN2 TYRO3 EPHA2 MERTK TBC1D3I TBC1D3G SPDYE4 CTSL TBC1D3K TBC1D3F	3.01e-08	1028	103	21	GO:0043085
GeneOntologyBiologicalProcess	regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D NTRK3 CD109 OAS3 RALGAPA2 TBC1D3C TBC1D3B PREX2 EPHA2 TBC1D3I TBC1D3G CTSL RASAL1 TBC1D3K TBC1D3F	6.19e-08	878	103	19	GO:0051336
GeneOntologyBiologicalProcess	positive regulation of molecular function	AKAP6 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D AXL USP9X NTRK3 RALGAPA2 TBC1D3C TBC1D3B PREX2 AXIN2 TYRO3 STAC2 EPHA2 MERTK TBC1D3I TBC1D3G SPDYE4 CTSL TBC1D3K TBC1D3F	1.09e-07	1430	103	24	GO:0044093
GeneOntologyBiologicalProcess	peroxisomal membrane transport	USP9X PEX5L ABCD3 ABCD2	4.00e-06	22	103	4	GO:0015919
GeneOntologyBiologicalProcess	peroxisomal transport	USP9X PEX5L ABCD3 ABCD2	4.00e-06	22	103	4	GO:0043574
GeneOntologyBiologicalProcess	vagina development	AXL TYRO3 MERTK	1.94e-05	11	103	3	GO:0060068
GeneOntologyBiologicalProcess	dense core granule docking	UNC13B UNC13A	2.47e-05	2	103	2	GO:0061790
GeneOntologyBiologicalProcess	peroxisome organization	USP9X PEX5L ABCD3 ABCD2	4.22e-05	39	103	4	GO:0007031
GeneOntologyBiologicalProcess	synaptic vesicle docking	UNC13B PPFIA3 UNC13A	7.82e-05	17	103	3	GO:0016081
GeneOntologyBiologicalProcess	female genitalia development	AXL TYRO3 MERTK	1.30e-04	20	103	3	GO:0030540
GeneOntologyBiologicalProcess	long-chain fatty acid import into peroxisome	ABCD3 ABCD2	1.47e-04	4	103	2	GO:0015910
GeneOntologyBiologicalProcess	dense core granule priming	UNC13B UNC13A	1.47e-04	4	103	2	GO:0061789
GeneOntologyBiologicalProcess	regulation of short-term neuronal synaptic plasticity	UNC13B PPFIA3 UNC13A	1.74e-04	22	103	3	GO:0048172
GeneOntologyBiologicalProcess	neutrophil clearance	AXL MERTK	3.66e-04	6	103	2	GO:0097350
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	UNC13B PPFIA3 UNC13A	1.97e-04	23	104	3	GO:0098831
GeneOntologyCellularComponent	axonemal dynein complex	DNHD1 DNAI2 DNAH9	2.54e-04	25	104	3	GO:0005858
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.14e-13	49	103	10	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.67e-13	53	103	10	PF00566
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.96e-13	55	103	10	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.96e-13	55	103	10	IPR000195
Domain	SNF2_N	EP400 CHD4 RAD54B SHPRH	2.79e-05	32	103	4	IPR000330
Domain	SNF2_N	EP400 CHD4 RAD54B SHPRH	2.79e-05	32	103	4	PF00176
Domain	Arp1	ACTR1B ACTR1A	3.01e-05	2	103	2	IPR029909
Domain	C2	UNC13B RASA1 ITSN1 SYTL5 UNC13A RASAL1	8.70e-05	131	103	6	PF00168
Domain	Unc-13	UNC13B UNC13A	9.00e-05	3	103	2	IPR027080
Domain	C2	UNC13B RASA1 ITSN1 SYTL5 UNC13A RASAL1	1.11e-04	137	103	6	SM00239
Domain	Actin/actin-like_CS	ACTRT3 ACTR1B ACTR1A	1.25e-04	18	103	3	IPR020902
Domain	TyrKc	AXL NTRK3 TYRO3 EPHA2 MERTK	1.26e-04	88	103	5	SM00219
Domain	Tyr_kinase_cat_dom	AXL NTRK3 TYRO3 EPHA2 MERTK	1.26e-04	88	103	5	IPR020635
Domain	C2	UNC13B RASA1 ITSN1 SYTL5 UNC13A RASAL1	1.36e-04	142	103	6	PS50004
Domain	ACTINS_ACT_LIKE	ACTRT3 ACTR1B ACTR1A	1.48e-04	19	103	3	PS01132
Domain	-	UNC13B RASA1 ITSN1 SYTL5 UNC13A RASAL1	1.70e-04	148	103	6	2.60.40.150
Domain	ABC_membrane_2	ABCD3 ABCD2	1.79e-04	4	103	2	PF06472
Domain	PROTEIN_KINASE_TYR	AXL NTRK3 TYRO3 EPHA2 MERTK	1.99e-04	97	103	5	PS00109
Domain	Tyr_kinase_AS	AXL NTRK3 TYRO3 EPHA2 MERTK	1.99e-04	97	103	5	IPR008266
Domain	C2_dom	UNC13B RASA1 ITSN1 SYTL5 UNC13A RASAL1	2.96e-04	164	103	6	IPR000008
Domain	SH3_1	RASA1 ITSN1 STAC2 DLG2 ARHGEF4 CTTN	2.96e-04	164	103	6	PF00018
Domain	Munc13_dom-2	UNC13B UNC13A	2.98e-04	5	103	2	IPR014772
Domain	Membr_traf_MHD	UNC13B UNC13A	2.98e-04	5	103	2	PF10540
Domain	MHD2	UNC13B UNC13A	2.98e-04	5	103	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13A	2.98e-04	5	103	2	IPR019558
Domain	DUF1041	UNC13B UNC13A	2.98e-04	5	103	2	SM01145
Domain	DUF1041	UNC13B UNC13A	6.21e-04	7	103	2	PF06292
Domain	Munc13_1	UNC13B UNC13A	6.21e-04	7	103	2	IPR014770
Domain	ANION_EXCHANGER_2	SLC4A1 SLC4A5	6.21e-04	7	103	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A1 SLC4A5	6.21e-04	7	103	2	PS00219
Domain	CAPS_dom	UNC13B UNC13A	6.21e-04	7	103	2	IPR010439
Domain	MHD1	UNC13B UNC13A	6.21e-04	7	103	2	PS51258
Domain	Actin	ACTRT3 ACTR1B ACTR1A	6.54e-04	31	103	3	IPR004000
Domain	Actin	ACTRT3 ACTR1B ACTR1A	6.54e-04	31	103	3	PF00022
Domain	ACTIN	ACTRT3 ACTR1B ACTR1A	6.54e-04	31	103	3	SM00268
Domain	Pkinase_Tyr	AXL NTRK3 TYRO3 EPHA2 MERTK	7.41e-04	129	103	5	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	AXL NTRK3 TYRO3 EPHA2 MERTK	1.00e-03	138	103	5	IPR001245
Domain	Band3_cytoplasmic_dom	SLC4A1 SLC4A5	1.06e-03	9	103	2	IPR013769
Domain	Band_3_cyto	SLC4A1 SLC4A5	1.06e-03	9	103	2	PF07565
Domain	-	SLC4A1 SLC4A5	1.06e-03	9	103	2	3.40.1100.10
Domain	SH3	RASA1 ITSN1 STAC2 DLG2 ARHGEF4 CTTN	1.26e-03	216	103	6	SM00326
Domain	SH3	RASA1 ITSN1 STAC2 DLG2 ARHGEF4 CTTN	1.26e-03	216	103	6	PS50002
Domain	GDS_CDC24_CS	ITSN1 PREX2 ARHGEF4	1.29e-03	39	103	3	IPR001331
Domain	Na_channel_asu	SCN11A SCN3A	1.32e-03	10	103	2	IPR001696
Domain	HCO3_cotransp	SLC4A1 SLC4A5	1.32e-03	10	103	2	PF00955
Domain	HCO3_transpt_C	SLC4A1 SLC4A5	1.32e-03	10	103	2	IPR011531
Domain	Na_trans_assoc	SCN11A SCN3A	1.32e-03	10	103	2	IPR010526
Domain	PTrfase/Anion_transptr	SLC4A1 SLC4A5	1.32e-03	10	103	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A1 SLC4A5	1.32e-03	10	103	2	IPR003020
Domain	Na_trans_assoc	SCN11A SCN3A	1.32e-03	10	103	2	PF06512
Domain	SH3_domain	RASA1 ITSN1 STAC2 DLG2 ARHGEF4 CTTN	1.38e-03	220	103	6	IPR001452
Domain	fn3	IL31RA AXL TYRO3 EPHA2 MERTK	2.04e-03	162	103	5	PF00041
Domain	RasGAP	RASA1 RASAL1	2.62e-03	14	103	2	SM00323
Domain	Dynein_HC_stalk	DNHD1 DNAH9	2.62e-03	14	103	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH9	2.62e-03	14	103	2	IPR013602
Domain	DHC_N2	DNHD1 DNAH9	2.62e-03	14	103	2	PF08393
Domain	MT	DNHD1 DNAH9	2.62e-03	14	103	2	PF12777
Domain	RasGAP_CS	RASA1 RASAL1	2.62e-03	14	103	2	IPR023152
Domain	-	DNHD1 EP400 CHD4 TEP1 PAPSS1 RAD54B ABCD3 SHPRH DLG2 ABCD2 DNAH9	2.71e-03	746	103	11	3.40.50.300
Domain	Helicase_C	EP400 CHD4 RAD54B SHPRH	2.91e-03	107	103	4	PF00271
Domain	HELICc	EP400 CHD4 RAD54B SHPRH	2.91e-03	107	103	4	SM00490
Domain	Helicase_C	EP400 CHD4 RAD54B SHPRH	3.01e-03	108	103	4	IPR001650
Domain	DHC_fam	DNHD1 DNAH9	3.02e-03	15	103	2	IPR026983
Domain	RasGAP	RASA1 RASAL1	3.02e-03	15	103	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	RASA1 RASAL1	3.02e-03	15	103	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	RASA1 RASAL1	3.02e-03	15	103	2	PS50018
Domain	Dynein_heavy_dom	DNHD1 DNAH9	3.02e-03	15	103	2	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH9	3.02e-03	15	103	2	PF03028
Domain	HELICASE_CTER	EP400 CHD4 RAD54B SHPRH	3.12e-03	109	103	4	PS51194
Domain	HELICASE_ATP_BIND_1	EP400 CHD4 RAD54B SHPRH	3.12e-03	109	103	4	PS51192
Domain	DEXDc	EP400 CHD4 RAD54B SHPRH	3.12e-03	109	103	4	SM00487
Domain	Glycoside_hydrolase_SF	SPAM1 NAGLU GAA	3.12e-03	53	103	3	IPR017853
Domain	Helicase_ATP-bd	EP400 CHD4 RAD54B SHPRH	3.22e-03	110	103	4	IPR014001
Domain	-	RASA1 RASAL1	3.44e-03	16	103	2	1.10.506.10
Domain	Actin_CS	ACTR1B ACTR1A	3.44e-03	16	103	2	IPR004001
Domain	FN3	IL31RA AXL TYRO3 EPHA2 MERTK	3.62e-03	185	103	5	SM00060
Domain	C1_1	UNC13B STAC2 UNC13A	3.84e-03	57	103	3	PF00130
Domain	ACTINS_2	ACTR1B ACTR1A	3.88e-03	17	103	2	PS00432
Domain	ig	AXL NTRK3 TYRO3 IL1R2 MERTK	4.05e-03	190	103	5	PF00047
Domain	Immunoglobulin	AXL NTRK3 TYRO3 IL1R2 MERTK	4.05e-03	190	103	5	IPR013151
Domain	RasGAP_dom	RASA1 RASAL1	4.35e-03	18	103	2	IPR001936
Domain	FN3	IL31RA AXL TYRO3 EPHA2 MERTK	4.92e-03	199	103	5	PS50853
Domain	DH_1	ITSN1 PREX2 ARHGEF4	5.09e-03	63	103	3	PS00741
Domain	ZF_DAG_PE_1	UNC13B STAC2 UNC13A	5.32e-03	64	103	3	PS00479
Domain	ZF_DAG_PE_2	UNC13B STAC2 UNC13A	5.32e-03	64	103	3	PS50081
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B STAC2 TBC1D3I TBC1D3G TBC1D3K	2.92e-10	99	83	10	M46448
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	ACTR1B ACTR1A DNAI2 DNAH9	1.77e-05	27	83	4	M47755
Pathway	KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT	ACTR1B ACTR1A DNAI2 DNAH9	1.16e-04	43	83	4	M47669
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	ACTR1B ACTR1A DNAI2 DNAH9	1.39e-04	45	83	4	M47670
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.11e-28	11	105	11	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F	2.84e-09	74	105	7	16625196
Pubmed	Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis.	AXL TYRO3 MERTK	2.67e-08	3	105	3	23071254
Pubmed	TAM receptors are dispensable in the phagocytosis and killing of bacteria.	AXL TYRO3 MERTK	2.67e-08	3	105	3	19625016
Pubmed	TAM receptor ligands in lupus: protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus.	AXL TYRO3 MERTK	2.67e-08	3	105	3	20637106
Pubmed	High incidence of distal vaginal atresia in mice lacking Tyro3 RTK subfamily.	AXL TYRO3 MERTK	2.67e-08	3	105	3	18393392
Pubmed	Receptor tyrosine kinases Tyro3, Axl, and Mertk differentially contribute to antibody-induced arthritis.	AXL TYRO3 MERTK	2.67e-08	3	105	3	37537628
Pubmed	The role of Tyro 3 subfamily receptors in the regulation of hemostasis and megakaryocytopoiesis.	AXL TYRO3 MERTK	2.67e-08	3	105	3	17488688
Pubmed	Systemic autoimmunity in TAM triple knockout mice causes inflammatory brain damage and cell death.	AXL TYRO3 MERTK	2.67e-08	3	105	3	23840307
Pubmed	Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis.	AXL TYRO3 MERTK	2.67e-08	3	105	3	30335822
Pubmed	Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.	AXL TYRO3 MERTK	2.67e-08	3	105	3	25074926
Pubmed	Functions of TAM RTKs in regulating spermatogenesis and male fertility in mice.	AXL TYRO3 MERTK	2.67e-08	3	105	3	19602523
Pubmed	Tyro-3 family receptors are essential regulators of mammalian spermatogenesis.	AXL TYRO3 MERTK	2.67e-08	3	105	3	10227296
Pubmed	Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells.	AXL TYRO3 MERTK	2.67e-08	3	105	3	17442946
Pubmed	TAM receptors and their ligand-mediated activation: Role in atherosclerosis.	AXL TYRO3 MERTK	2.67e-08	3	105	3	33234243
Pubmed	Post-translational modifications of the ligands: Requirement for TAM receptor activation.	AXL TYRO3 MERTK	2.67e-08	3	105	3	33234244
Pubmed	Recent advancements in role of TAM receptors on efferocytosis, viral infection, autoimmunity, and tissue repair.	AXL TYRO3 MERTK	2.67e-08	3	105	3	33234241
Pubmed	Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases.	AXL TYRO3 MERTK	2.67e-08	3	105	3	16751775
Pubmed	Immunological role of TAM receptors in the cancer microenvironment.	AXL TYRO3 MERTK	2.67e-08	3	105	3	33234245
Pubmed	TAM Receptors Are Not Required for Zika Virus Infection in Mice.	AXL TYRO3 MERTK	2.67e-08	3	105	3	28423319
Pubmed	TAM receptors in apoptotic cell clearance, autoimmunity, and cancer.	AXL TYRO3 MERTK	2.67e-08	3	105	3	23662598
Pubmed	The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity.	AXL TYRO3 MERTK	2.67e-08	3	105	3	26523970
Pubmed	TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.	AXL TYRO3 MERTK	2.67e-08	3	105	3	18620092
Pubmed	TAM receptors support neural stem cell survival, proliferation and neuronal differentiation.	AXL TYRO3 MERTK	2.67e-08	3	105	3	25514676
Pubmed	New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis.	AXL TYRO3 MERTK	2.67e-08	3	105	3	32051695
Pubmed	TAM receptor knockout mice are susceptible to retinal autoimmune induction.	AXL TYRO3 MERTK	2.67e-08	3	105	3	21467176
Pubmed	Development of a spontaneous liver disease resembling autoimmune hepatitis in mice lacking tyro3, axl and mer receptor tyrosine kinases.	AXL TYRO3 MERTK	2.67e-08	3	105	3	23799121
Pubmed	The association of Tyro3/Axl/Mer signaling with inflammatory response, disease activity in patients with primary Sjögren's syndrome.	AXL TYRO3 MERTK	2.67e-08	3	105	3	25881761
Pubmed	Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.	AXL TYRO3 MERTK	2.67e-08	3	105	3	15733062
Pubmed	Transcriptome analysis of neural progenitor cells by a genetic dual reporter strategy.	AXL TYRO3 MERTK	2.67e-08	3	105	3	21805534
Pubmed	Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation.	AXL TYRO3 MERTK	2.67e-08	3	105	3	30541554
Pubmed	TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer.	AXL TYRO3 MERTK	2.67e-08	3	105	3	30765874
Pubmed	Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation.	AXL TYRO3 MERTK	2.67e-08	3	105	3	21192804
Pubmed	TAM Family Receptor Kinase Inhibition Reverses MDSC-Mediated Suppression and Augments Anti-PD-1 Therapy in Melanoma.	AXL TYRO3 MERTK	2.67e-08	3	105	3	31451482
Pubmed	Increased soluble phagocytic receptors sMer, sTyro3 and sAxl and reduced phagocytosis in juvenile-onset systemic lupus erythematosus.	AXL TYRO3 MERTK	2.67e-08	3	105	3	25878564
Pubmed	Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family.	AXL TYRO3 MERTK	2.67e-08	3	105	3	11452127
Pubmed	Increased hematopoietic cells in the mertk-/- mouse peritoneal cavity: a result of augmented migration.	AXL TYRO3 MERTK	2.67e-08	3	105	3	20483720
Pubmed	Tyro3 family-mediated cell entry of Ebola and Marburg viruses.	AXL TYRO3 MERTK	2.67e-08	3	105	3	17005688
Pubmed	Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl.	AXL TYRO3 MERTK	1.07e-07	4	105	3	8621659
Pubmed	Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.	AXL TYRO3 MERTK	1.07e-07	4	105	3	15650770
Pubmed	Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target.	AXL TYRO3 MERTK	1.07e-07	4	105	3	33532004
Pubmed	The Gas6/TAM System and Multiple Sclerosis.	AXL TYRO3 MERTK	1.07e-07	4	105	3	27801848
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	1.07e-07	4	105	3	12359748
Pubmed	Increased sMer, but not sAxl, sTyro3, and Gas6 relate with active disease in juvenile systemic lupus erythematosus.	AXL TYRO3 MERTK	1.07e-07	4	105	3	31655933
Pubmed	Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinases.	AXL TYRO3 MERTK	1.07e-07	4	105	3	16365397
Pubmed	Diversification of TAM receptor tyrosine kinase function.	AXL TYRO3 MERTK	1.07e-07	4	105	3	25194421
Pubmed	Gas6 and the Tyro 3 receptor tyrosine kinase subfamily regulate the phagocytic function of Sertoli cells.	AXL TYRO3 MERTK	1.07e-07	4	105	3	18159085
Pubmed	Sertoli cell-initiated testicular innate immune response through toll-like receptor-3 activation is negatively regulated by Tyro3, Axl, and mer receptors.	AXL TYRO3 MERTK	1.07e-07	4	105	3	20363878
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	1.07e-07	4	105	3	8406013
Pubmed	Expression of growth arrest-specific gene 6 and its receptors in dysfunctional human renal allografts.	AXL TYRO3 MERTK	1.07e-07	4	105	3	12768229
Pubmed	TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL.	AXL TYRO3 MERTK	1.07e-07	4	105	3	31230815
Pubmed	Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.	AXL TYRO3 MERTK	1.07e-07	4	105	3	28184013
Pubmed	Expression of the vitamin K-dependent proteins GAS6 and protein S and the TAM receptor tyrosine kinases in human atherosclerotic carotid plaques.	AXL TYRO3 MERTK	1.07e-07	4	105	3	21384080
Pubmed	Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization.	AXL TYRO3 MERTK	1.07e-07	4	105	3	20546121
Pubmed	Differential Interaction of Platelet-Derived Extracellular Vesicles With Circulating Immune Cells: Roles of TAM Receptors, CD11b, and Phosphatidylserine.	AXL TYRO3 MERTK	1.07e-07	4	105	3	30619243
Pubmed	Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases.	AXL TYRO3 MERTK	1.07e-07	4	105	3	8939948
Pubmed	Association study between polymorphims in GAS6-TAM genes and carotid atherosclerosis.	AXL TYRO3 MERTK	1.07e-07	4	105	3	20664904
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	2.66e-07	5	105	3	12604796
Pubmed	Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis.	AXL TYRO3 MERTK	2.66e-07	5	105	3	23259948
Pubmed	Role of Gas6 in erythropoiesis and anemia in mice.	AXL TYRO3 MERTK	2.66e-07	5	105	3	18188450
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	2.66e-07	5	105	3	8471161
Pubmed	Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.	AXL TYRO3 MERTK	2.66e-07	5	105	3	25265470
Pubmed	Loss of Growth arrest specific gene 6 (Gas6) results in altered GnRH neuron migration, delayed vaginal opening and sexual maturation in mice.	AXL TYRO3 MERTK	2.66e-07	5	105	3	24978606
Pubmed	Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.	AXL TYRO3 MERTK	2.66e-07	5	105	3	22043818
Pubmed	Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor.	AXL TYRO3 MERTK	2.66e-07	5	105	3	20348395
Pubmed	Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration.	AXL TYRO3 MERTK	5.31e-07	6	105	3	18787040
Pubmed	The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity.	AXL TYRO3 MERTK	5.31e-07	6	105	3	27034374
Pubmed	TAM receptors affect adult brain neurogenesis by negative regulation of microglial cell activation.	AXL TYRO3 MERTK	5.31e-07	6	105	3	24244024
Pubmed	An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.	AXL TYRO3 MERTK	5.31e-07	6	105	3	24509082
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	USP9X ITSN1 GPRIN3 CRNKL1 ARFGAP2 EPHA2 TNRC6A	8.62e-07	169	105	7	31462741
Pubmed	Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis.	AXL TYRO3 MERTK	1.48e-06	8	105	3	19729839
Pubmed	Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like region.	AXL TYRO3 MERTK	3.16e-06	10	105	3	21084607
Pubmed	Molecular and functional architecture of striatal dopamine release sites.	UNC13B PPFIA3 UNC13A	4.33e-06	11	105	3	34767769
Pubmed	The protein tyrosine kinase family of the human genome.	AXL NTRK3 TYRO3 EPHA2 MERTK	5.49e-06	83	105	5	11114734
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	NTRK3 TYRO3 EPHA2 MERTK	6.59e-06	40	105	4	30898150
Pubmed	TAM receptors are pleiotropic inhibitors of the innate immune response.	AXL TYRO3 MERTK	7.48e-06	13	105	3	18083102
Pubmed	TAM receptors and the regulation of erythropoiesis in mice.	AXL MERTK	9.03e-06	2	105	2	19211638
Pubmed	Increased Circulating and Urinary Levels of Soluble TAM Receptors in Diabetic Nephropathy.	TYRO3 MERTK	9.03e-06	2	105	2	28668213
Pubmed	Regulation of microglial phagocytosis and inflammatory gene expression by Gas6 acting on the Axl/Mer family of tyrosine kinases.	AXL MERTK	9.03e-06	2	105	2	18247125
Pubmed	Increased Mer and Axl receptor tyrosine kinase expression on glomeruli in lupus nephritis.	AXL MERTK	9.03e-06	2	105	2	28127639
Pubmed	MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL.	AXL MERTK	9.03e-06	2	105	2	23617806
Pubmed	Chromosomal localization of the adrenoleukodystrophy-related gene in man and mice.	ABCD3 ABCD2	9.03e-06	2	105	2	9195160
Pubmed	Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.	UNC13B UNC13A	9.03e-06	2	105	2	12070347
Pubmed	Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor.	AXL MERTK	9.03e-06	2	105	2	30723115
Pubmed	The TAM receptor tyrosine kinases Axl and Mer drive the maintenance of highly phagocytic macrophages.	AXL MERTK	9.03e-06	2	105	2	35967387
Pubmed	TYRO3 and EPHA2 Expression Are Dysregulated in Breast Cancer.	TYRO3 EPHA2	9.03e-06	2	105	2	39327735
Pubmed	Regulation of insulin exocytosis by Munc13-1.	UNC13B UNC13A	9.03e-06	2	105	2	12871971
Pubmed	Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.	UNC13B UNC13A	9.03e-06	2	105	2	17561838
Pubmed	Hypothalamic but not pituitary or ovarian defects underlie the reproductive abnormalities in Axl/Tyro3 null mice.	AXL TYRO3	9.03e-06	2	105	2	21539887
Pubmed	Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer.	AXL MERTK	9.03e-06	2	105	2	32571802
Pubmed	Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis.	TYRO3 MERTK	9.03e-06	2	105	2	21496228
Pubmed	Molecular cloning of a novel receptor tyrosine kinase, tif, highly expressed in human ovary and testis.	TYRO3 EPHA2	9.03e-06	2	105	2	8108143
Pubmed	Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.	UNC13B UNC13A	9.03e-06	2	105	2	23070049
Pubmed	Axl and Mertk Receptors Cooperate to Promote Breast Cancer Progression by Combined Oncogenic Signaling and Evasion of Host Antitumor Immunity.	AXL MERTK	9.03e-06	2	105	2	33239426
Pubmed	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.	UNC13B UNC13A	9.03e-06	2	105	2	28489077
Pubmed	Cloning and developmental expression analysis of the murine c-mer tyrosine kinase.	AXL MERTK	9.03e-06	2	105	2	7784083
Pubmed	Opposing Roles of Tyrosine Kinase Receptors Mer and Axl Determine Clinical Outcomes in Experimental Immune-Mediated Nephritis.	AXL MERTK	9.03e-06	2	105	2	27527599
Pubmed	Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.	UNC13B UNC13A	9.03e-06	2	105	2	10440375
Pubmed	Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.	UNC13B UNC13A	9.03e-06	2	105	2	22066784
Pubmed	Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.	UNC13B UNC13A	9.03e-06	2	105	2	32187536
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B STAC2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.31e-15	149	105	12	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B STAC2 TBC1D3F	1.17e-07	99	105	6	17q12
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	AXL NTRK3 TYRO3 MERTK	9.16e-06	40	60	4	321
GeneFamily	ATP binding cassette subfamily D	ABCD3 ABCD2	6.47e-05	4	60	2	808
GeneFamily	UNC13 homologs	UNC13B UNC13A	6.47e-05	4	60	2	836
GeneFamily	Fibronectin type III domain containing	IL31RA AXL TYRO3 EPHA2 MERTK	1.88e-04	160	60	5	555
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN11A SCN3A	3.84e-04	9	60	2	1203
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA1 RASAL1	4.79e-04	10	60	2	830
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ITSN1 PREX2 ARHGEF4	1.37e-03	66	60	3	722
GeneFamily	Dyneins, axonemal	DNAI2 DNAH9	1.43e-03	17	60	2	536
GeneFamily	Claudins	CLDN25 CLDN16	2.62e-03	23	60	2	488
GeneFamily	Ataxins\|Trinucleotide repeat containing	EP400 TNRC6A	3.09e-03	25	60	2	775
GeneFamily	Sterile alpha motif domain containing	PPFIA3 EPHA2 KAZN	3.12e-03	88	60	3	760
GeneFamily	PHD finger proteins	CHD4 SHPRH KDM2A	3.33e-03	90	60	3	88
GeneFamily	Immunoglobulin like domain containing	AXL TYRO3 IL1R2 MERTK	3.85e-03	193	60	4	594
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASA1 ITSN1 ARHGEF4 RASAL1	4.85e-03	206	60	4	682
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL31RA IL1R2	8.56e-03	42	60	2	602
GeneFamily	WD repeat domain containing	TEP1 WDR19 DNAI2 PWP2	1.11e-02	262	60	4	362
GeneFamily	PDZ domain containing	PREX2 SNX27 DLG2	1.41e-02	152	60	3	1220
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NTRK3 TYRO3 MERTK	1.64e-02	161	60	3	593
Coexpression	GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_UP	SCN11A FMO1 AXL MARCHF6 CHD4 NLN SNX27 ABCD2	1.28e-06	200	103	8	M6635
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B MERTK TBC1D3G TBC1D3K TBC1D3F	1.91e-11	90	103	10	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B ARHGEF4 TBC1D3G TBC1D3K TBC1D3F	8.75e-08	213	103	10	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B ARHGEF4 TBC1D3G TBC1D3K TBC1D3F	8.75e-08	213	103	10	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B ARHGEF4 TBC1D3G TBC1D3K TBC1D3F	2.87e-07	242	103	10	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D AXL TEP1 TBC1D3C TBC1D3B AXIN2 WDR19 ACTR1B GDPD5 EPHA2 ZER1 NIPA1 ARHGEF4 MERTK TBC1D3G GAA TBC1D3K TBC1D3F	6.19e-06	1466	103	21	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	9.28e-06	281	103	9	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	9.28e-06	281	103	9	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	2.60e-05	320	103	9	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	Myeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3	GALNT3 AXL ITSN1 GSAP TEP1 ITGAX DLG2 MERTK ABCD2 CTSL	2.66e-05	403	103	10	GSM605853_500
CoexpressionAtlas	Mesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D PIEZO1 RNPEPL1 TBC1D3C TBC1D3B TYRO3 EPHA2 NIPA1 ARHGEF4 MERTK TBC1D3G CTSL TBC1D3K TBC1D3F	3.78e-05	1153	103	17	PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D AXL TBC1D3C TBC1D3B WDR19 ACTR1B GDPD5 ARHGEF4 TBC1D3G GAA TBC1D3K TBC1D3F	2.08e-04	1075	103	15	PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlas	Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3	GALNT3 AXL GSAP ITGAX NLN MERTK ABCD2 CTSL ADIPOR2	2.26e-04	425	103	9	GSM538282_500
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DRC7 GPRIN3 RALGAPA2 PEX5L LIPC DNAH9	1.20e-06	144	105	6	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL GSAP ITGAX MERTK ABCD2 ADIPOR2	3.37e-06	172	105	6	584af6537685cb459bf0fc298e6f46872016c116
ToppCell	facs-Kidney-nan-24m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT NTRK3 SLC4A1 SSC5D STAC2 AOC3	4.37e-06	180	105	6	f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AXL NAGLU GPRIN3 MERTK CTSL GAA	4.37e-06	180	105	6	6f8fa9fa91cd25b92584972bb34d90c483222f52
ToppCell	droplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 AXL GSAP ITGAX ABCD2 ADIPOR2	4.51e-06	181	105	6	8fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 AXL GSAP ITGAX ABCD2 ADIPOR2	4.66e-06	182	105	6	be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL GSAP ITGAX MERTK ABCD2 ADIPOR2	4.96e-06	184	105	6	8e5fc2bdd3071e782aa8c56b8a39f8ea8f03f623
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GALNT3 AXL GSAP ITGAX ABCD2 ADIPOR2	4.96e-06	184	105	6	8fa30789c9d583188667cf375d2218e392dd40bc
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GALNT3 AXL GSAP ITGAX ABCD2 ADIPOR2	5.12e-06	185	105	6	4bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCell	Myeloid-B_(Activated_Macrophage)\|World / shred on cell class and cell subclass (v4)	AXL GSAP ITGAX MERTK ABCD2 ADIPOR2	5.28e-06	186	105	6	33d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell	droplet-Lung-nan-18m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 AXL GSAP ITGAX ABCD2 ADIPOR2	5.44e-06	187	105	6	f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCell	droplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 AXL GSAP ITGAX ABCD2 ADIPOR2	5.44e-06	187	105	6	f20e7a1751694390f535ffb27b97e887220f8695
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AXL ITSN1 GPRIN3 ITGAX MERTK CTSL	5.61e-06	188	105	6	3be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GALNT3 AXL GSAP ITGAX ABCD2 ADIPOR2	5.78e-06	189	105	6	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	Myeloid-Myeloid-B_(Activated_Macrophage)\|Myeloid / shred on cell class and cell subclass (v4)	AXL GSAP ITGAX ABCD2 CTSL ADIPOR2	6.14e-06	191	105	6	7bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPT AXL NTRK3 CD109 AXIN2 SSC5D	6.14e-06	191	105	6	fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Mucinous_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	GPRIN3 PEX5L TBC1D3B TBC1D3I UNC13A	1.97e-05	139	105	5	898322c0af83038a82fe01da99209d619c5a6156
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL GSAP ITGAX SLC4A1 TYRO3	3.43e-05	156	105	5	5caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL GSAP ITGAX SLC4A1 TYRO3	3.43e-05	156	105	5	758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	GALNT3 AXL GSAP ITGAX ADIPOR2	3.87e-05	160	105	5	694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TRRAP ITGAX DLG2 ARHGEF4 GAA	4.23e-05	163	105	5	63b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT3 AXL GSAP MERTK ADIPOR2	5.31e-05	171	105	5	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	DRC7 GALNT3 CD109 MMEL1 DNAH9	5.31e-05	171	105	5	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC1\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AKAP6 GPRIN3 ITGAX GDPD5 DNAI2	5.61e-05	173	105	5	d13ae4046a25ee0fb492ddedf44583a879a432e9
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTRT3 AXL ITGAX IL1R2 ABCD2	5.61e-05	173	105	5	7456a417c5c1d4ba25f9489065aae322421308a6
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTRT3 AXL ITGAX IL1R2 ABCD2	5.61e-05	173	105	5	35586a9e5f15b41609b6224e33eb3aa3cb7e03b7
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Hematologic\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTRT3 AXL ITGAX IL1R2 ABCD2	5.61e-05	173	105	5	cd635751f999e12b14c0accfa1c4c1fd3c1d4540
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRC7 IL31RA WDR19 EPHA2 KAZN	5.77e-05	174	105	5	a9f34d1237f335d27c5560ff514368f4709f9144
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 GPRIN3 TEP1 ITGAX ABCD2	5.93e-05	175	105	5	3bca1aac2a2a1f46753b5f9462888f144ed8327b
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITSN1 ITGAX EPHA2 SCN3A CTSL	6.09e-05	176	105	5	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITSN1 ITGAX EPHA2 SCN3A CTSL	6.09e-05	176	105	5	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	AXL ITSN1 ITGAX MERTK CTSL	6.77e-05	180	105	5	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 AXL NMUR1 ITGAX ADIPOR2	7.14e-05	182	105	5	3dec003bad0f3716cf8163861a9d4302a7d6df8c
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL ITGAX MERTK ABCD2 ADIPOR2	7.51e-05	184	105	5	fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GALNT3 AXL ITGAX ABCD2 ADIPOR2	7.51e-05	184	105	5	15ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GALNT3 AXL ITGAX ABCD2 ADIPOR2	7.51e-05	184	105	5	bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 AXL ITGAX ABCD2 ADIPOR2	7.71e-05	185	105	5	afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 AXL ITGAX ABCD2 ADIPOR2	7.71e-05	185	105	5	775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AKAP6 ITSN1 DLG2 MERTK CTSL	7.91e-05	186	105	5	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT FMO1 AXL ABCD2 CTSL	7.91e-05	186	105	5	cc94e0c5d1665d2ea2bb871ad79d8e1ec2249fb5
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL ITGAX MERTK ABCD2 ADIPOR2	7.91e-05	186	105	5	7950e03ea080238c168b9d807e217f459acdfb28
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AKAP6 ITSN1 DLG2 MERTK CTSL	7.91e-05	186	105	5	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AKAP6 NTRK3 CD109 SYTL5 AOC3	8.11e-05	187	105	5	218c9b4f28499389c43005d9626af2ac01066027
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AKAP6 NTRK3 CD109 SYTL5 AOC3	8.11e-05	187	105	5	c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 NTRK3 CD109 SYTL5 AOC3	8.32e-05	188	105	5	61f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCell	droplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 NTRK3 CD109 SYTL5 AOC3	8.32e-05	188	105	5	7553ef7de3575af4cf34704b405b551c1af8eb83
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GALNT3 AXL ITGAX ABCD2 ADIPOR2	8.53e-05	189	105	5	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL GSAP ITGAX ABCD2 ADIPOR2	8.53e-05	189	105	5	287e59104687fe1665232c52993889f0f2c97f17
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AXL GSAP ITGAX ABCD2 ADIPOR2	8.53e-05	189	105	5	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	AKAP6 NPTX2 PEX5L SCN3A UNC13A	8.53e-05	189	105	5	de06ef69f3f97b3f21dc269eb6965da9b2f6e3f8
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	AXL GPRIN3 AOC3 CTSL GAA	8.53e-05	189	105	5	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL NMUR1 PREX2 AOC3 KAZN	8.74e-05	190	105	5	7e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPRIN3 PWP2 MERTK CTSL GAA	8.74e-05	190	105	5	0a944da2aaaef9289b2a4ffe360b0338724fd59b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AKAP6 AXL NTRK3 STAC2 ACAN	8.74e-05	190	105	5	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL NMUR1 PREX2 AOC3 KAZN	8.74e-05	190	105	5	7fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	AXL GPRIN3 AOC3 KAZN ADIPOR2	8.96e-05	191	105	5	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AKAP6 AXL NTRK3 ACAN SCN3A	9.18e-05	192	105	5	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	IPF-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	AKAP6 NTRK3 STAC2 ACAN AOC3	9.18e-05	192	105	5	9b06c7336624ef21f8e5393725b56038a8028e57
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AKAP6 AXL NTRK3 ACAN SCN3A	9.18e-05	192	105	5	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AXL NTRK3 STAC2 ACAN AOC3	9.41e-05	193	105	5	7631bf3362b4fa061ffeab4879ab12c4708dc4c0
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT AXL SSC5D CTSL GAA	9.41e-05	193	105	5	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT FMO1 AXL CTSL GAA	9.41e-05	193	105	5	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AXL NTRK3 STAC2 ACAN AOC3	9.41e-05	193	105	5	8d15c63f2ae48d0a00d7ef5fdafa917ab8ad0571
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT FMO1 AXL CTSL GAA	9.41e-05	193	105	5	85faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCell	facs-MAT-Fat-3m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT FMO1 AXL CTSL GAA	9.41e-05	193	105	5	110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCell	P28-Mesenchymal-myocytic_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPT AXL NTRK3 CD109 AOC3	9.64e-05	194	105	5	83e45441c74b7f50b6725876b583229280179dc2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AXL NTRK3 ACAN SCN3A AOC3	9.64e-05	194	105	5	5099e6ad7c19e5f8b73449d904aaefd97f1b1959
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AXL NTRK3 ACAN SCN3A AOC3	9.64e-05	194	105	5	71734ef7b34ab33b349595368176fa0e1175d4d0
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPT NTRK3 CD109 SSC5D LIPC	9.64e-05	194	105	5	7bf6edefd13047e04665dbe34051ef3f481f85a4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITSN1 GSAP ITGAX MERTK CTSL	9.64e-05	194	105	5	45708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPT NTRK3 CD109 SSC5D LIPC	9.64e-05	194	105	5	19e5beae2c1f8bf42cbe618e89810ce7b01a396c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AXL NTRK3 ACAN SCN3A AOC3	9.87e-05	195	105	5	e10b21e4dba4483efc4c82d6e395524246ca14a8
ToppCell	PND01-Mesenchymal-Mesenchymal_structural\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPT PREX2 AXIN2 MERTK CTSL	9.87e-05	195	105	5	6bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCell	Monocytes-M2-like_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	AXL ITSN1 MERTK CTSL GAA	9.87e-05	195	105	5	10fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CFuPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	NTRK3 GPRIN3 PEX5L GDPD5 KAZN	9.87e-05	195	105	5	574354ef4bcefeb9856b65d19bb92e2cffe5dc7a
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPT NTRK3 CD109 AXIN2 SSC5D	9.87e-05	195	105	5	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITSN1 GSAP ITGAX MERTK CTSL	9.87e-05	195	105	5	247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AXL NTRK3 ACAN SCN3A AOC3	9.87e-05	195	105	5	9ab3c5b0fb12d406408122a535b717bfe184bbcf
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AXL NTRK3 ACAN SCN3A AOC3	9.87e-05	195	105	5	21263d138c81f6a0219f2cd93126cfafd35732b2
ToppCell	Macrophages-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	AXL NTRK3 GPRIN3 AOC3 GAA	9.87e-05	195	105	5	2af46e87947c16a7c2c367637e606cfbb8a78528
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPT NTRK3 CD109 AXIN2 SSC5D	9.87e-05	195	105	5	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPT PREX2 AXIN2 MERTK CTSL	9.87e-05	195	105	5	a3b468125e48f072255cede7645f6692298ecf54
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UNC13B GALNT3 PIEZO1 IL1R2 SYTL5	1.01e-04	196	105	5	847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCell	Control-Myeloid-Macrophage\|Control / Disease state, Lineage and Cell class	CD109 ITGAX IL1R2 MERTK CTSL	1.01e-04	196	105	5	e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCell	ILEUM-non-inflamed-(3)_moDC\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	AXL ITSN1 ITGAX IL1R2 MERTK	1.01e-04	196	105	5	e10f01172fd076d6892906853f9375d4c3058951
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AXL NTRK3 PREX2 ACAN AOC3	1.01e-04	196	105	5	754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPT PREX2 AXIN2 MERTK CTSL	1.04e-04	197	105	5	06a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area\|World / Primary Cells by Cluster	NTRK3 ITSN1 GPRIN3 PEX5L KAZN	1.04e-04	197	105	5	79b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33\|World / Primary Cells by Cluster	NTRK3 ITSN1 GPRIN3 PEX5L KAZN	1.04e-04	197	105	5	d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Dendritic_cell / Region, Cell class and subclass	DNHD1 SCN11A TBC1D3L ITSN1 RALGAPA2	1.04e-04	197	105	5	8545baf923ddf84c5ce9414a36d810603be52401
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UNC13B GALNT3 PIEZO1 IL1R2 SYTL5	1.04e-04	197	105	5	d624f3a105b19f19a0dd253ce8de3ed13adc1f01
ToppCell	nucseq-Immune-Immune_Myeloid-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITSN1 CD109 ITGAX MERTK CTSL	1.04e-04	197	105	5	6f41c8f815851968849428ec92c16745bd01a3fb
ToppCell	Transverse-(5)_Dendritic_cell-(53)_Lymphoid_DC\|Transverse / shred on region, Cell_type, and subtype	DNHD1 SCN11A TBC1D3L ITSN1 MERTK	1.04e-04	197	105	5	15b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	AXL GPRIN3 IL1R2 MERTK CTSL	1.04e-04	197	105	5	075044c17f1c52008cd3c292c15cbf485b50411e
ToppCell	nucseq-Immune-Immune_Myeloid-IM-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITSN1 CD109 ITGAX MERTK CTSL	1.04e-04	197	105	5	304044ace926943b8eb588f686ecbe5d1689a809
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPT PREX2 AXIN2 MERTK CTSL	1.04e-04	197	105	5	d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Transverse / Region, Cell class and subclass	DNHD1 SCN11A TBC1D3L ITSN1 MERTK	1.04e-04	197	105	5	a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AXL ITGAX MERTK CTSL GAA	1.06e-04	198	105	5	e1a0c809302a3b304775bd708201ad412a98d711
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AKAP6 AXL NTRK3 SCN3A AOC3	1.06e-04	198	105	5	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ITSN1 ITGAX MERTK CTSL GAA	1.06e-04	198	105	5	76db943db8b5483754f38e4c6af7f5955cec420c
Drug	(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A	SPAM1 RNPEPL1 NAGLU OAS3 GSAP PPFIA3 PREX2 ARHGEF4 MERTK SLC25A23	1.23e-08	195	98	10	4980_DN
Drug	Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A	SPAM1 GSAP PPFIA3 GDPD5 EPHA2 RAD54B KDM2A MERTK	2.20e-06	197	98	8	7350_DN
Disease	Gastric Adenocarcinoma	AXL NTRK3 TRRAP EPHA2	1.36e-05	45	95	4	C0278701
Disease	Xerocytosis	PIEZO1 SLC4A1	3.07e-05	3	95	2	C0272051
Disease	Colorectal Carcinoma	AKAP6 UNC13B RNPEPL1 CD109 PEX5L PREX2 AXIN2 ABCD3 KDM2A ABCD2	8.94e-05	702	95	10	C0009402
Disease	wellbeing measurement, alcohol consumption measurement	AKAP6 PREX2 STAC2 UNC13A	9.76e-05	74	95	4	EFO_0007869, EFO_0007878
Disease	adrenoleukodystrophy (implicated_via_orthology)	ABCD3 ABCD2	2.13e-04	7	95	2	DOID:10588 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN11A SCN3A	4.54e-04	10	95	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN11A SCN3A	4.54e-04	10	95	2	DOID:0080422 (implicated_via_orthology)
Disease	trans/cis-18:2 fatty acid measurement, trans fatty acid measurement	GPRIN3 NLN	5.54e-04	11	95	2	EFO_0006821, EFO_0006825
Disease	Parkinson disease	UNC13B PTGES2 NAGLU GPRIN3 IL1R2 DLG2	6.11e-04	321	95	6	MONDO_0005180
Disease	colorectal cancer (is_implicated_in)	NTRK3 CHD4 AXIN2 RAD54B	6.42e-04	121	95	4	DOID:9256 (is_implicated_in)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN11A SCN3A	6.63e-04	12	95	2	DOID:0060170 (implicated_via_orthology)
Disease	basal cell carcinoma (is_implicated_in)	RASA1 CRNKL1	6.63e-04	12	95	2	DOID:2513 (is_implicated_in)
Disease	body weight	AKAP6 UNC13B PPFIA3 AXIN2 LIPC ACAN TNRC6A DLG2 KDM2A KAZN PRMT7 NUTM2F	7.29e-04	1261	95	12	EFO_0004338
Disease	macrophage inflammatory protein 1b measurement	TBC1D3 TOPAZ1 TBC1D3B TBC1D3F	9.94e-04	136	95	4	EFO_0008219
Disease	anemia (implicated_via_orthology)	SLC4A1 SLC4A5	1.05e-03	15	95	2	DOID:2355 (implicated_via_orthology)
Disease	sensorineural hearing loss (implicated_via_orthology)	DNAI2 DNAH9	1.69e-03	19	95	2	DOID:10003 (implicated_via_orthology)
Disease	lung cancer (is_implicated_in)	CHD4 AXIN2 IL1R2	1.78e-03	74	95	3	DOID:1324 (is_implicated_in)
Disease	CCL4 measurement	TBC1D3 TBC1D3F	1.88e-03	20	95	2	EFO_0004751
Disease	epilepsy (implicated_via_orthology)	UNC13B SCN11A SCN3A UNC13A	1.93e-03	163	95	4	DOID:1826 (implicated_via_orthology)
Disease	Colorectal Neoplasms	CD109 AXIN2 ABCD3 KDM2A ABCD2	2.05e-03	277	95	5	C0009404
Disease	LEOPARD Syndrome	RASA1 EPHA2	2.27e-03	22	95	2	C0175704
Disease	Noonan Syndrome	RASA1 EPHA2	2.70e-03	24	95	2	C0028326

Protein segments in the cluster

Peptide	Gene	Start	Entry
TVEVWNKGLIWDTMV	UNC13A	61	Q9UPW8
EDAVMTAVRAWEFWN	EP400	2186	Q96L91
HIVQREGGWDAVMDW	ABCD2	591	Q9UBJ2
QELRWMEAARWVQLE	SLC4A1	71	P02730
ERGLITSWEDMEIMW	ACTRT3	71	Q9BYD9
SCVAAWWDMVDRNLR	ABHD12B	21	Q7Z5M8
EHGVVRDWNDMERIW	ACTR1B	76	P42025
IEVMDATNREWWWGR	ARHGEF4	221	Q9NR80
NEMETWIMGIWEVCV	CLDN25	41	C9JDP6
WIMGIWEVCVDREEV	CLDN25	46	C9JDP6
IVATWTDCWMVNADD	CLDN16	21	Q9Y5I7
EEGDRSQDVWQWMLE	AXIN2	611	Q9Y2T1
SRWDTDAAWGMDRVE	ARFGAP2	371	Q8N6H7
EPTECWWEEINRAGM	DPT	86	Q07507
EVVWRAEMEEALLEW	DNHD1	1516	Q96M86
FSASTDGQVMWWDIR	DNAI2	281	Q9GZS0
DWARWEREIDWMALN	NAGLU	146	P54802
DVAGLENWVWAEDMV	AOC3	531	Q16853
WWQMQEESAAPERGK	CCDC27	316	Q2M243
DWNPATDIQAMSRVW	RAD54B	741	Q9Y620
LRVELWDWDMVGKND	RASAL1	196	O95294
MEEFVCKVWEGRWRV	ADIPOR2	91	Q86V24
NELEDGWMWVTNLRT	RASA1	311	P20936
FWVPVELNQEAVWMD	ITGAX	971	P20702
WKAGTVQAWLEVVMA	KAZN	446	Q674X7
DRVMWSVVSQWTDGL	NMUR1	316	Q9HB89
CDIRWMQLWQEQGEA	NTRK3	166	Q16288
SDVWAFGVTMWEIAT	MERTK	781	Q12866
DVNTWMIEWFPDVDS	IL31RA	351	Q8NI17
RDVMVWSNERVMGWV	PPFIA3	1036	O75145
MEWEVDEVLNWTNTL	MFI	226	Q8NCR3
ANQRWDVPEAVEWMS	ENOSF1	251	Q7L5Y1
EWEEMARRNWISENQ	PEX5L	286	Q8IYB4
SVDGVLENWIWQMVA	LIPC	91	P11150
DDMNWNALEWDRAAE	MARCHF6	256	O60337
VVAMSAVAQLWEDEW	GDPD5	136	Q8WTR4
VAMDRWNETVGLEWE	MMEL1	201	Q495T6
TEWEELINEWANIMD	RALGAPA2	631	Q2PPJ7
ERSAAVFIQAWWRGM	IQCF5	11	A8MTL0
CVVMIWHEKGEWNDV	ACAN	2416	P16112
KVDMQWVQVLAEGWA	PAPSS1	261	O43252
AEDFVWAQWDMSEQR	GSAP	206	A4D1B5
LTWRAEQEGGMQFWV	CD109	1111	Q6YHK3
VAGARQVFERWMEWQ	CRNKL1	326	Q9BZJ0
QVFERWMEWQPEEQA	CRNKL1	331	Q9BZJ0
STVDFIDWVDNMWPR	KDM2A	161	Q9Y2K7
RGSWAQDGDESWMQR	KDM2A	881	Q9Y2K7
QDGDESWMQREVWMS	KDM2A	886	Q9Y2K7
QVVLSWWDIEMDPEG	PRMT7	276	Q9NVM4
IWGGENIEMSFRVWQ	GALNT3	386	Q14435
SASDVWSFGIVMWEV	EPHA2	796	P29317
WEGARNAIMTQWDRT	FMO1	481	Q01740
TVLEQQDMWWFGEVQ	ITSN1	941	Q15811
EHGIVKDWNDMERIW	ACTR1A	76	P61163
REEAAEWAEWARMEK	DRC7	16	Q8IY82
TNPTALAWWEDMVAE	GAA	491	P10253
INASDDEWWQARRVM	DLG2	571	Q15700
DEWWQARRVMLEGDS	DLG2	576	Q15700
PVDNLGMAVIDWEEW	SPAM1	136	P38567
WWTTEVGMAFARLEE	DNAH9	1726	Q9NYC9
EWRANIDTVMAWFTE	ENPP7	171	Q6UWV6
VRDVVWDEQGMTWEV	GPRIN3	681	Q6ZVF9
TIINWEREFEMWAPD	CHD4	786	Q14839
DIVWWAGTIAMAVGQ	NIPA1	66	Q7RTP0
ILDEMRAQLESWWQD	OAS3	496	Q9Y6K5
WLRDWMEGSGRVTDV	NYX	346	Q9GZU5
MTLEEGLWQAMREWQ	NUTM2F	251	A1L443
VDWMDSQGEEQRLWQ	SYTL5	691	Q8TDW5
EEEEWLTAERMAEWI	USP9X	376	Q93008
NATWEEMWLSEGLAT	RNPEPL1	366	Q9HAU8
VEWWRICLDEAQMVE	SHPRH	811	Q149N8
EARTEEMKWRQWADD	PTGES2	226	Q9H7Z7
WEMCRILNDEAAWNE	WDR19	666	Q8NEZ3
VFRVLCGEWIETMWD	SCN3A	936	Q9NY46
QRWGTVCDDSWDMRD	SSC5D	486	A1L4H1
MDVVEVAGSWWAQER	TBC1D3L	1	B9A6J9
VAGSWWAQEREDIIM	TBC1D3L	6	B9A6J9
WTTRDGMWEAFQDGE	NPTX2	316	P47972
EEETRMWAQDGALWL	IL1R2	81	P27930
EREGGWDSVQDWMDV	ABCD3	556	P28288
ERRWEAIVMQAVQWQ	AKAP6	1171	Q13023
GMNEEGWRRAVWEKN	CTSL	41	P07711
EVPSQMLENWVWDVD	NLN	526	Q9BYT8
MDVVEVAGSWWAQER	TBC1D3B	1	A6NDS4
VAGSWWAQEREDIIM	TBC1D3B	6	A6NDS4
MDVVEVAGSWWAQER	TBC1D3H	1	P0C7X1
VAGSWWAQEREDIIM	TBC1D3H	6	P0C7X1
REEVEERMWAAIQSW	ZER1	656	Q7Z7L7
ETAMEGEWPWQASLQ	TMPRSS11F	211	Q6ZWK6
RLDSMVELWAWREGA	TEP1	1861	Q99973
MDVVEVAGSWWAQER	TBC1D3F	1	A6NER0
VAGSWWAQEREDIIM	TBC1D3F	6	A6NER0
DDIITNIEMIDDGWW	CTTN	516	Q14247
MSTWVFGAERWDNLI	PWP2	166	Q15269
RWRTWVSPEEMEEIQ	SPDYE4	206	A6NLX3
GDRIMLVDDSNEDWW	STAC2	316	Q6ZMT1
DVWSFGVTMWEIATR	AXL	731	P30530
QHDGDQMEWKESARW	SLC4A5	121	Q9BY07
VIAFEWDEMQRWDTD	SNX27	466	Q96L92
NEMETWEASRRWLDQ	PREX2	1296	Q70Z35
SVEVWNKGLIWDTMV	UNC13B	61	O14795
MDVVEVAGSWWAQER	TBC1D3E	1	A0A087X179
VAGSWWAQEREDIIM	TBC1D3E	6	A0A087X179
SLDGAIWVMRESEWI	TOPAZ1	1426	Q8N9V7
DRDGTMTIDWQEWRD	SLC25A23	126	Q9BV35
VFRILCGEWIENMWE	SCN11A	761	Q9UI33
MDVVEVAGSWWAQER	TBC1D3D	1	A0A087WVF3
VAGSWWAQEREDIIM	TBC1D3D	6	A0A087WVF3
VELRAVMDWVWTDTT	PIEZO1	2116	Q92508
MDVVEVAGSWWAQER	TBC1D3G	1	Q6DHY5
VAGSWWAQEREDIIM	TBC1D3G	6	Q6DHY5
MDVVEVAGSWWAQER	TBC1D3	1	Q8IZP1
VAGSWWAQEREDIIM	TBC1D3	6	Q8IZP1
IVDQMVWFRENWHEE	TRRAP	3321	Q9Y4A5
MDVVEVAGSWWAQER	TBC1D3K	1	A0A087X1G2
VAGSWWAQEREDIIM	TBC1D3K	6	A0A087X1G2
WEEEEDVEIGMWNSN	TNRC6A	1141	Q8NDV7
VQSDVWAFGVTMWEI	TYRO3	711	Q06418
MDVVEVAGSWWAQER	TBC1D3I	1	A0A087WXS9
VAGSWWAQEREDIIM	TBC1D3I	6	A0A087WXS9
MDVVEVAGSWWAQER	TBC1D3C	1	Q6IPX1
VAGSWWAQEREDIIM	TBC1D3C	6	Q6IPX1