Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

7.51e-284317428GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 P2RY4 OR4C11 OR4C16 OR6K2 GPR85 OR4F4 OR4C45 OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 CALCRL OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

6.94e-238847431GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 P2RY4 OR4C11 OR4C16 OR6K2 GPR85 OR4F4 OR4C45 OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 CALCRL OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

1.60e-1713537431GO:0004888
GeneOntologyMolecularFunctionsteroid hormone binding

ATP1A1 ATP1A2 ATP1A3

1.69e-067743GO:1990239
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

NALCN KCNK1 SCNN1D CACNA1H ATP1A1 ATP1A2 ATP1A3

3.32e-06171747GO:0015081
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A1 ATP1A2 ATP1A3

5.75e-0610743GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A1 ATP1A2 ATP1A3

5.75e-0610743GO:0005391
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A1 ATP1A2 ATP1A3

7.89e-0611743GO:0008556
GeneOntologyMolecularFunctionsodium channel activity

NALCN KCNK1 SCNN1D CACNA1H

4.11e-0552744GO:0005272
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

NALCN SLC39A1 KCNK1 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

5.39e-05465749GO:0046873
GeneOntologyMolecularFunctionodorant binding

OR14A2 OR6N2 OR6K2 OR14I1 OR8K3

1.09e-04127745GO:0005549
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP1A1 ATP1A2 ATP1A3

3.19e-0436743GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP1A1 ATP1A2 ATP1A3

3.19e-0436743GO:0015662
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNK1 KCNQ1 ATP1A1 ATP1A2 ATP1A3

3.90e-04167745GO:0015079
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

NALCN SLC39A1 KCNK1 SCNN1D KCNQ1 ANO7 CACNA1H ATP1A1 ATP1A2 ATP1A3

4.68e-047587410GO:0015318
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

NALCN SLC39A1 KCNK1 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

5.02e-04627749GO:0022890
GeneOntologyMolecularFunctionhormone binding

CALCRL ATP1A1 ATP1A2 ATP1A3

5.82e-04103744GO:0042562
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

NALCN SLC39A1 KCNK1 SCNN1D KCNQ1 ANO7 CACNA1H ATP1A1 ATP1A2 ATP1A3

6.64e-047937410GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

NALCN SLC39A1 KCNK1 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

7.57e-04664749GO:0008324
GeneOntologyMolecularFunctionpotassium ion binding

ATP1A1 ATP1A2

1.20e-0314742GO:0030955
GeneOntologyMolecularFunctionphosphatidate phosphatase activity

PLPPR4 PLPPR3

1.20e-0314742GO:0008195
GeneOntologyMolecularFunctionsodium ion binding

ATP1A1 ATP1A2

1.20e-0314742GO:0031402
GeneOntologyMolecularFunctiontransmembrane transporter activity

NALCN SLC39A1 SLC43A1 KCNK1 SCNN1D KCNQ1 ANO7 CACNA1H ATP1A1 ATP1A2 ATP1A3 CYB561A3

1.25e-0311807412GO:0022857
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP1A1 ATP1A2 ATP1A3

1.58e-0362743GO:0019829
GeneOntologyMolecularFunctionlipid phosphatase activity

PLPPR4 PLPPR3

2.22e-0319742GO:0042577
GeneOntologyMolecularFunctionnarrow pore channel activity

NALCN KCNK1

2.22e-0319742GO:0022842
GeneOntologyMolecularFunctionleak channel activity

NALCN KCNK1

2.22e-0319742GO:0022840
GeneOntologyMolecularFunctiontransporter activity

NALCN SLC39A1 SLC43A1 KCNK1 SCNN1D KCNQ1 ANO7 CACNA1H ATP1A1 ATP1A2 ATP1A3 CYB561A3

2.63e-0312897412GO:0005215
GeneOntologyMolecularFunctionprotein-folding chaperone binding

ATP1A1 ATP1A2 ATP1A3 CDC25A

3.02e-03161744GO:0051087
GeneOntologyMolecularFunctionphosphoric ester hydrolase activity

GDPD4 PLPPR4 PLPPR3 ATP1A1 ATP1A2 CDC25A

3.08e-03386746GO:0042578
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

NALCN CACNA1H

4.16e-0326742GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

ATP1A1 ATP1A2

4.16e-0326742GO:0031420
GeneOntologyMolecularFunctionphosphatase activity

PLPPR4 PLPPR3 ATP1A1 ATP1A2 CDC25A

4.25e-03287745GO:0016791
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ATP1A1 ATP1A2 ATP1A3 CYB561A3

4.32e-03178744GO:0015399
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCNK1 KCNQ1

4.48e-0327742GO:0015271
GeneOntologyMolecularFunctionmannosyltransferase activity

DPY19L2 PIGM

4.81e-0328742GO:0000030
GeneOntologyMolecularFunctionmonoatomic ion channel activity

NALCN KCNK1 SCNN1D KCNQ1 ANO7 CACNA1H

7.09e-03459746GO:0005216
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP1A1 ATP1A2 ATP1A3

7.74e-03109743GO:0042626
GeneOntologyMolecularFunctiongated channel activity

KCNK1 SCNN1D KCNQ1 ANO7 CACNA1H

7.99e-03334745GO:0022836
GeneOntologyMolecularFunctionpalmitoyltransferase activity

ZDHHC18 CPT1C

8.30e-0337742GO:0016409
GeneOntologyMolecularFunctionmonoatomic cation channel activity

NALCN KCNK1 SCNN1D KCNQ1 CACNA1H

8.90e-03343745GO:0005261
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

GDPD4 PLPPR4 HIBCH CPT1C PLPPR3 ATP1A1 ATP1A2 CDC25A

9.86e-03807748GO:0016788
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

2.11e-284327328GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

1.65e-274657328GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

5.31e-274857328GO:0050907
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 SCNN1D OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

5.93e-275477329GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 KCNQ1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

3.48e-265827329GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

4.52e-265247328GO:0009593
GeneOntologyBiologicalProcessdetection of stimulus

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 KCNQ1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

1.54e-237227329GO:0051606
GeneOntologyBiologicalProcesssensory perception

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 DLL4 OR4C16 OR6K2 OR4F4 OR4C45 SCNN1D OR1P1 KCNQ1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 WDR1 TECTA OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

2.21e-2310727333GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 PLPPR4 OR6N2 OR4K13 OR4S2 P2RY4 OR4C11 OR4C16 OR6K2 GPR85 OR4F4 OR4C45 OR1P1 KCNQ1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 CALCRL OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

7.74e-2013957333GO:0007186
GeneOntologyBiologicalProcessresponse to glycoside

ATP1A1 ATP1A2 ATP1A3

4.23e-075733GO:1903416
GeneOntologyBiologicalProcesssodium ion transmembrane transport

NALCN KCNK1 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

7.16e-07208738GO:0035725
GeneOntologyBiologicalProcesscell communication by electrical coupling involved in cardiac conduction

ATP1A1 ATP1A2 ATP1A3 TBX5

2.03e-0626734GO:0086064
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

KCNQ1 ATP1A1 ATP1A2 ATP1A3 TBX5

2.08e-0659735GO:0086065
GeneOntologyBiologicalProcessintracellular sodium ion homeostasis

SCNN1D ATP1A1 ATP1A2 ATP1A3

3.69e-0630734GO:0006883
GeneOntologyBiologicalProcesssodium ion transport

NALCN KCNK1 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

5.73e-06275738GO:0006814
GeneOntologyBiologicalProcessestablishment or maintenance of transmembrane electrochemical gradient

ATP1A1 ATP1A2 ATP1A3

6.88e-0611733GO:0010248
GeneOntologyBiologicalProcessregulation of resting membrane potential

NALCN KCNK1 ATP1A3

6.88e-0611733GO:0060075
GeneOntologyBiologicalProcesscell communication by electrical coupling

ATP1A1 ATP1A2 ATP1A3 TBX5

6.96e-0635734GO:0010644
GeneOntologyBiologicalProcesspotassium ion homeostasis

KCNQ1 ATP1A1 ATP1A2 ATP1A3

8.73e-0637734GO:0055075
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

1.12e-05142736GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

1.12e-05142736GO:0098659
GeneOntologyBiologicalProcessimport across plasma membrane

SLC43A1 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

1.71e-05230737GO:0098739
GeneOntologyBiologicalProcessintracellular potassium ion homeostasis

ATP1A1 ATP1A2 ATP1A3

2.79e-0517733GO:0030007
GeneOntologyBiologicalProcesssodium ion export across plasma membrane

ATP1A1 ATP1A2 ATP1A3

2.79e-0517733GO:0036376
GeneOntologyBiologicalProcesscardiac conduction

KCNQ1 ATP1A1 ATP1A2 ATP1A3 TBX5

2.80e-05100735GO:0061337
GeneOntologyBiologicalProcesspotassium ion import across plasma membrane

KCNQ1 ATP1A1 ATP1A2 ATP1A3

3.18e-0551734GO:1990573
GeneOntologyBiologicalProcesssodium ion homeostasis

SCNN1D ATP1A1 ATP1A2 ATP1A3

3.18e-0551734GO:0055078
GeneOntologyBiologicalProcessmembrane repolarization

KCNQ1 ATP1A1 WDR1 ATP1A2

4.61e-0556734GO:0086009
GeneOntologyBiologicalProcessregulation of membrane potential

NALCN KCNK1 KCNQ1 CACNA1H ATP1A1 WDR1 ATP1A2 ATP1A3 TBX5

1.54e-04559739GO:0042391
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

NALCN KCNK1 KCNQ1 ATP1A1 ATP1A2 ATP1A3

1.72e-04232736GO:0071805
GeneOntologyBiologicalProcessregulation of heart contraction

KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3 TBX5

2.52e-04249736GO:0008016
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction

KCNQ1 CACNA1H ATP1A1 ATP1A2

2.81e-0489734GO:0055117
GeneOntologyBiologicalProcessexport across plasma membrane

KCNQ1 ATP1A1 ATP1A2 ATP1A3

3.06e-0491734GO:0140115
GeneOntologyBiologicalProcesscardiac muscle contraction

KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

3.16e-04167735GO:0060048
GeneOntologyBiologicalProcesscardiac muscle cell contraction

KCNQ1 CACNA1H ATP1A1 ATP1A2

3.32e-0493734GO:0086003
GeneOntologyBiologicalProcesspotassium ion transport

NALCN KCNK1 KCNQ1 ATP1A1 ATP1A2 ATP1A3

4.04e-04272736GO:0006813
GeneOntologyBiologicalProcesscardiac muscle cell membrane repolarization

KCNQ1 ATP1A1 WDR1

4.12e-0441733GO:0099622
GeneOntologyBiologicalProcessblood circulation

OR51E2 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3 OCLN TBX5

4.56e-04648739GO:0008015
GeneOntologyBiologicalProcessregulation of cardiac muscle cell contraction

CACNA1H ATP1A1 ATP1A2

4.74e-0443733GO:0086004
GeneOntologyBiologicalProcessregulation of striated muscle contraction

KCNQ1 CACNA1H ATP1A1 ATP1A2

6.50e-04111734GO:0006942
GeneOntologyBiologicalProcessheart contraction

KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3 TBX5

6.54e-04298736GO:0060047
GeneOntologyBiologicalProcesspositive regulation of heart contraction

KCNQ1 ATP1A1 ATP1A2

6.97e-0449733GO:0045823
GeneOntologyBiologicalProcessregulation of muscle contraction

KCNQ1 CACNA1H CALCRL ATP1A1 ATP1A2

7.51e-04202735GO:0006937
GeneOntologyBiologicalProcessheart process

KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3 TBX5

7.90e-04309736GO:0003015
GeneOntologyBiologicalProcesspositive regulation of blood circulation

KCNQ1 ATP1A1 ATP1A2

8.78e-0453733GO:1903524
GeneOntologyBiologicalProcessregulation of actin filament-based movement

CACNA1H ATP1A1 ATP1A2

8.78e-0453733GO:1903115
GeneOntologyBiologicalProcessmembrane depolarization

CACNA1H ATP1A2 ATP1A3 TBX5

8.98e-04121734GO:0051899
GeneOntologyBiologicalProcessstriated muscle contraction

KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

1.03e-03217735GO:0006941
GeneOntologyBiologicalProcessregulation of blood circulation

KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3 TBX5

1.04e-03326736GO:1903522
GeneOntologyBiologicalProcessactin-mediated cell contraction

KCNQ1 CACNA1H ATP1A1 ATP1A2

1.07e-03127734GO:0070252
GeneOntologyBiologicalProcesscirculatory system process

OR51E2 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3 OCLN TBX5

1.09e-03733739GO:0003013
GeneOntologyBiologicalProcessthalamus development

PTCHD1 ATP1A3

1.44e-0316732GO:0021794
GeneOntologyBiologicalProcessL-ascorbic acid metabolic process

ATP1A2 ATP1A3

1.44e-0316732GO:0019852
GeneOntologyBiologicalProcessregulation of blood pressure

OR51E2 SCNN1D KCNQ1 ATP1A1 ATP1A2

1.53e-03237735GO:0008217
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

OR51E2 SCNN1D ATP1A1 ATP1A2 ATP1A3

1.59e-03239735GO:0071383
GeneOntologyBiologicalProcesspositive regulation of striated muscle contraction

KCNQ1 ATP1A1

1.62e-0317732GO:0045989
GeneOntologyBiologicalProcessglucocorticoid biosynthetic process

CACNA1H ATP1A1

1.82e-0318732GO:0006704
GeneOntologyCellularComponentsodium:potassium-exchanging ATPase complex

ATP1A1 ATP1A2 ATP1A3

9.16e-0612743GO:0005890
GeneOntologyCellularComponentphotoreceptor inner segment membrane

ATP1A1 ATP1A3

7.38e-054742GO:0060342
GeneOntologyCellularComponenttransmembrane transporter complex

NALCN CPT1C KCNK1 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

9.35e-05523749GO:1902495
GeneOntologyCellularComponenttransporter complex

NALCN CPT1C KCNK1 SCNN1D KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

1.37e-04550749GO:1990351
GeneOntologyCellularComponentsarcolemma

KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3

5.71e-04190745GO:0042383
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP1A1 ATP1A2 ATP1A3

6.98e-0449743GO:0090533
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP1A1 ATP1A2 ATP1A3

9.79e-0455743GO:0098533
HumanPhenoAbnormal T-wave

KCNQ1 ATP1A2 ATP1A3 TBX5

5.24e-0637174HP:0005135
HumanPhenoEpisodic quadriplegia

ATP1A2 ATP1A3

1.05e-052172HP:0200072
HumanPhenoEpisodic hemiplegia

ATP1A2 ATP1A3

6.27e-054172HP:0012194
HumanPhenoSkewfoot

ATP1A2 ATP1A3

1.56e-046172HP:0032649
HumanPhenoOcular flutter

ATP1A2 ATP1A3

1.56e-046172HP:0031931
DomainOlfact_rcpt

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6

1.20e-233936724IPR000725
Domain7tm_1

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR6N2 OR4K13 OR4S2 P2RY4 OR4C11 OR4C16 OR6K2 GPR85 OR4F4 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6

1.45e-206776726PF00001
DomainG_PROTEIN_RECEP_F1_1

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR6N2 OR4K13 OR4S2 P2RY4 OR4C11 OR4C16 OR6K2 GPR85 OR4F4 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6

1.94e-206856726PS00237
DomainG_PROTEIN_RECEP_F1_2

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR6N2 OR4K13 OR4S2 P2RY4 OR4C11 OR4C16 OR6K2 GPR85 OR4F4 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6

2.42e-206916726PS50262
DomainGPCR_Rhodpsn

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR6N2 OR4K13 OR4S2 P2RY4 OR4C11 OR4C16 OR6K2 GPR85 OR4F4 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6

2.50e-206926726IPR000276
DomainGPCR_Rhodpsn_7TM

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR6N2 OR4K13 OR4S2 P2RY4 OR4C11 OR4C16 OR6K2 GPR85 OR4F4 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4F15 OR4F6

1.93e-196706725IPR017452
DomainP-type_ATPase_IIC

ATP1A1 ATP1A2 ATP1A3

8.76e-076673IPR005775
Domain-

ATP1A1 ATP1A2 ATP1A3

2.39e-05166731.20.1110.10
DomainATPase_P-typ_TM_dom

ATP1A1 ATP1A2 ATP1A3

2.39e-0516673IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP1A1 ATP1A2 ATP1A3

2.89e-0517673IPR006068
DomainCation_ATPase_C

ATP1A1 ATP1A2 ATP1A3

2.89e-0517673PF00689
DomainCation_ATPase_N

ATP1A1 ATP1A2 ATP1A3

3.46e-0518673PF00690
DomainCation_ATPase_N

ATP1A1 ATP1A2 ATP1A3

3.46e-0518673SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A1 ATP1A2 ATP1A3

4.10e-0519673IPR004014
Domain-

ATP1A1 ATP1A2 ATP1A3

2.03e-04326732.70.150.10
Domain-

ATP1A1 ATP1A2 ATP1A3

2.03e-04326733.40.1110.10
DomainATPase_P-typ_cyto_domN

ATP1A1 ATP1A2 ATP1A3

2.66e-0435673IPR023299
DomainATPase_P-typ_P_site

ATP1A1 ATP1A2 ATP1A3

2.89e-0436673IPR018303
DomainP_typ_ATPase

ATP1A1 ATP1A2 ATP1A3

2.89e-0436673IPR001757
DomainATPASE_E1_E2

ATP1A1 ATP1A2 ATP1A3

2.89e-0436673PS00154
DomainATPase_P-typ_transduc_dom_A

ATP1A1 ATP1A2 ATP1A3

3.14e-0437673IPR008250
DomainE1-E2_ATPase

ATP1A1 ATP1A2 ATP1A3

3.14e-0437673PF00122
Domain-

PLPPR4 PLPPR3

1.87e-03186721.20.144.10
DomainacidPPc

PLPPR4 PLPPR3

1.87e-0318672SM00014
DomainP_Acid_Pase_2/haloperoxidase

PLPPR4 PLPPR3

2.31e-0320672IPR000326
DomainPAP2

PLPPR4 PLPPR3

2.31e-0320672PF01569
DomainHAD-like_dom

ATP1A1 ATP1A2 ATP1A3

2.87e-0379673IPR023214
DomainIon_trans_dom

NALCN KCNQ1 CACNA1H

7.99e-03114673IPR005821
DomainIon_trans

NALCN KCNQ1 CACNA1H

7.99e-03114673PF00520
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

1.53e-264176328M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 SCNN1D OR1P1 OR4F17 OR14I1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

9.08e-236366329M41834
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR3A1 OR51E2 OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR4F17 OR14I1 OR8K3 OR4K5 OR4K15 OR10X1 OR4F15 OR4F6 OR51F1

1.10e-213896324M14091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR51E2 OR14A2 OR4F4 OR8K3 OR10X1

1.47e-0570635MM14984
PathwayREACTOME_CARDIAC_CONDUCTION

KCNK1 KCNQ1 ATP1A1 ATP1A2 ATP1A3 TBX5

2.42e-05130636M27454
PathwayREACTOME_MUSCLE_CONTRACTION

KCNK1 KCNQ1 CACNA1H ATP1A1 ATP1A2 ATP1A3 TBX5

3.24e-05203637M5485
PathwayREACTOME_CARDIAC_CONDUCTION

KCNK1 KCNQ1 ATP1A1 ATP1A2 ATP1A3

9.48e-05103635MM15196
PathwayKEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION

ATP1A1 ATP1A2 ATP1A3

1.41e-0423633M4361
PathwayREACTOME_ION_CHANNEL_TRANSPORT

NALCN SCNN1D ANO7 ATP1A1 ATP1A2 ATP1A3

1.62e-04183636M997
PathwayREACTOME_MUSCLE_CONTRACTION

KCNK1 KCNQ1 ATP1A1 ATP1A2 ATP1A3

8.40e-04165635MM15026
PathwayKEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION

ATP1A1 ATP1A2 ATP1A3

8.62e-0442633M16473
PathwayREACTOME_ION_CHANNEL_TRANSPORT

NALCN ANO7 ATP1A1 ATP1A2 ATP1A3

1.12e-03176635MM15718
PathwayREACTOME_SENSORY_PERCEPTION

OR51E2 OR14A2 OR4F4 OR8K3 OR10X1

1.58e-03190635MM15687
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

PLPPR4 PLPPR3

1.73e-0314632M27331
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

PLPPR4 PLPPR3

1.73e-0314632MM15062
PathwayREACTOME_ION_HOMEOSTASIS

ATP1A1 ATP1A2 ATP1A3

1.79e-0354633MM15202
PathwayREACTOME_ION_HOMEOSTASIS

ATP1A1 ATP1A2 ATP1A3

1.79e-0354633M27460
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP1A1 ATP1A2 ATP1A3

1.89e-0355633M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP1A1 ATP1A2 ATP1A3

2.10e-0357633MM15643
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR3A1 OR51E2 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

2.88e-30340742411875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR3A1 OR51E2 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

2.88e-30340742411802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR3A1 OR51E2 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

3.57e-30343742432295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR3A1 OR51E2 OR4C3 OR4P4 OR4K2 OR4C15 OR14A2 OR6N2 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR4C45 OR1P1 OR8K3 OR4K5 OR4F21 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

4.41e-30346742414611657
Pubmed

The human olfactory receptor gene family.

OR3A1 OR51E2 OR4C3 OR4K2 OR4C15 OR6N2 OR4K13 OR4S2 OR4C11 OR4C16 OR6K2 OR4F4 OR1P1 OR8K3 OR4K5 OR4K15 OR10X1 OR4C5 OR4F15 OR4F6 OR51F1

5.14e-21541742114983052
Pubmed

Personal receptor repertoires: olfaction as a model.

OR4C16 OR1P1 OR8K3 OR10X1 OR4C5 OR51F1

1.97e-103874622908908
Pubmed

Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.

ATP1A1 ATP1A2 ATP1A3

9.25e-0937438203495
Pubmed

Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.

ATP1A1 ATP1A2 ATP1A3

9.25e-0937432822726
Pubmed

Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.

ATP1A1 ATP1A2 ATP1A3

9.25e-09374330819023
Pubmed

Na,K-ATPase and the role of alpha isoforms in behavior.

ATP1A1 ATP1A2 ATP1A3

9.25e-09374318044013
Pubmed

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.

ATP1A1 ATP1A2 ATP1A3

9.25e-09374326911348
Pubmed

Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.

ATP1A1 ATP1A2 ATP1A3

9.25e-09374317947306
Pubmed

Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.

ATP1A1 ATP1A2 ATP1A3

9.25e-09374325994790
Pubmed

Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.

ATP1A1 ATP1A2 ATP1A3

9.25e-09374319058785
Pubmed

Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.

ATP1A1 ATP1A2 ATP1A3

9.25e-09374328465228
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR4C15 OR4C11 OR4C16 OR8K3 OR4F21 OR4K15

1.25e-087474615081110
Pubmed

Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.

ATP1A1 ATP1A2 ATP1A3

3.69e-08474321731499
Pubmed

The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.

ATP1A1 ATP1A2 ATP1A3

3.69e-08474312458206
Pubmed

Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.

ATP1A1 ATP1A2 ATP1A3

3.69e-08474319751721
Pubmed

Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.

ATP1A1 ATP1A2 ATP1A3

3.69e-08474319376779
Pubmed

Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.

ATP1A1 ATP1A2 ATP1A3

3.69e-08474321849490
Pubmed

Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.

ATP1A1 ATP1A2 ATP1A3

3.69e-08474317446412
Pubmed

Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.

ATP1A1 ATP1A2 ATP1A3

3.69e-08474317234593
Pubmed

ZBTB20 is essential for cochlear maturation and hearing in mice.

KCNQ1 ATP1A1 ATP1A2 ATP1A3 TECTA

5.44e-084774537279265
Pubmed

Multiple genes encode the human Na+,K+-ATPase catalytic subunit.

ATP1A1 ATP1A2 ATP1A3

9.22e-0857433035563
Pubmed

The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.

ATP1A1 ATP1A2 ATP1A3

1.84e-0767433036582
Pubmed

Transport and pharmacological properties of nine different human Na, K-ATPase isozymes.

ATP1A1 ATP1A2 ATP1A3

1.84e-07674310636900
Pubmed

Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.

ATP1A1 ATP1A2 ATP1A3

3.22e-07774310837135
Pubmed

Expression and distribution of Na, K-ATPase isoforms in the human uterus.

ATP1A1 ATP1A2 ATP1A3

3.22e-07774320065300
Pubmed

Molecular genetics of Na,K-ATPase.

ATP1A1 ATP1A2 ATP1A3

3.22e-0777432158121
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR4P4 OR14A2 OR4S2 OR4F4 OR1P1 OR10X1 OR4F15

4.49e-0721974712213199
Pubmed

Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.

ATP1A1 ATP1A2 ATP1A3

5.14e-07874319683723
Pubmed

Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.

ATP1A1 ATP1A2 ATP1A3

5.14e-0787432885848
Pubmed

Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice.

ATP1A1 ATP1A2 ATP1A3

5.14e-07874323652595
Pubmed

The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.

ATP1A1 ATP1A2 ATP1A3

7.70e-07974315253893
Pubmed

A probabilistic classifier for olfactory receptor pseudogenes.

OR4C16 OR8K3 OR10X1 OR51F1

9.40e-073574416939646
Pubmed

Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.

ATP1A1 ATP1A2 ATP1A3

2.01e-061274327097562
Pubmed

Chromosomal assignments of 17 structural genes and 11 related DNA fragments in rats (Rattus norvegicus) by Southern blot analysis of rat x mouse somatic cell hybrid clones.

ATP1A1 ATP1A2 ATP1A3

3.31e-06147431572638
Pubmed

Decreased expression of both the alpha1- and alpha2-subunits of the Na-K-ATPase reduces maximal alveolar epithelial fluid clearance.

ATP1A1 ATP1A2

4.47e-06274215781423
Pubmed

DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase.

ATP1A1 ATP1A2

4.47e-06274222258333
Pubmed

Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes.

ATP1A1 ATP1A2

4.47e-06274222739122
Pubmed

Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.

ATP1A1 ATP1A3

4.47e-06274221498719
Pubmed

Identification of a specific role for the Na,K-ATPase alpha 2 isoform as a regulator of calcium in the heart.

ATP1A1 ATP1A2

4.47e-06274210360172
Pubmed

Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.

ATP1A1 ATP1A3

4.47e-06274223761886
Pubmed

Molecular cloning of the mouse ouabain-resistance gene.

ATP1A1 ATP1A2

4.47e-0627426324196
Pubmed

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.

ATP1A1 ATP1A2

4.47e-06274219376809
Pubmed

A real-time PCR method to genotype mutant mouse models with altered affinity for cardiotonic steroids on the Na,K-ATPase.

ATP1A1 ATP1A2

4.47e-06274235446892
Pubmed

New molecular determinants controlling the accessibility of ouabain to its binding site in human Na,K-ATPase alpha isoforms.

ATP1A1 ATP1A2

4.47e-06274214742675
Pubmed

Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases.

ATP1A1 ATP1A2

4.47e-06274211404365
Pubmed

Mice expressing ouabain-sensitive α1-Na,K-ATPase have increased susceptibility to pressure overload-induced cardiac hypertrophy.

ATP1A1 ATP1A2

4.47e-06274220952666
Pubmed

The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.

ATP1A1 ATP1A3

4.47e-0627423030810
Pubmed

ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.

ATP1A2 ATP1A3

4.47e-06274233880529
Pubmed

Ouabain-Sensitive alpha1 Na,K-ATPase enhances natriuretic response to saline load.

ATP1A1 ATP1A2

4.47e-06274218667729
Pubmed

Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the α1 or α2 Na-K-ATPase ouabain-binding site.

ATP1A1 ATP1A2

4.47e-06274221632957
Pubmed

Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease.

ATP1A2 ATP1A3

4.47e-06274224356962
Pubmed

Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location.

OR4F4 OR4F17

4.47e-06274211689484
Pubmed

Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes.

OR4F4 OR4F17

4.47e-06274211689483
Pubmed

The alpha(1)- and alpha(2)-isoforms of Na-K-ATPase play different roles in skeletal muscle contractility.

ATP1A1 ATP1A2

4.47e-06274211507009
Pubmed

The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations.

ATP1A2 ATP1A3

4.47e-06274218957371
Pubmed

Expression of alpha isoforms of the Na,K-ATPase in human heart.

ATP1A1 ATP1A2

4.47e-0627428391840
Pubmed

All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.

ATP1A1 ATP1A3

4.47e-06274211546672
Pubmed

Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.

ATP1A1 ATP1A3

4.47e-06274224391932
Pubmed

PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes.

ATP1A1 ATP1A2 ATP1A3

6.15e-061774336230906
Pubmed

RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks.

ATP1A1 ATP1A2 ATP1A3

8.74e-061974320861386
Pubmed

Decreased content of ascorbic acid (vitamin C) in the brain of knockout mouse models of Na+,K+-ATPase-related neurologic disorders.

ATP1A2 ATP1A3

1.34e-05374233544780
Pubmed

Translationally controlled tumor protein interacts with the third cytoplasmic domain of Na,K-ATPase alpha subunit and inhibits the pump activity in HeLa cells.

ATP1A1 ATP1A2

1.34e-05374215383549
Pubmed

Targeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearance.

ATP1A1 ATP1A2

1.34e-05374211557593
Pubmed

Purification of the human alpha2 Isoform of Na,K-ATPase expressed in Pichia pastoris. Stabilization by lipids and FXYD1.

ATP1A1 ATP1A2

1.34e-05374218052210
Pubmed

Isoform specificity of the Na/K-ATPase association and regulation by phospholemman.

ATP1A1 ATP1A2

1.34e-05374219638348
Pubmed

High glucose levels induce inhibition of Na,K-ATPase via stimulation of aldose reductase, formation of microtubules and formation of an acetylated tubulin/Na,K-ATPase complex.

ATP1A1 ATP1A2

1.34e-05374222565168
Pubmed

Simultaneously reduced NKCC1 and Na,K-ATPase expression in murine cochlear lateral wall contribute to conservation of endocochlear potential following a sensorineural hearing loss.

ATP1A1 ATP1A2

1.34e-05374221094218
Pubmed

Effect of resistance training on Na,K pump and Na+/H+ exchange protein densities in muscle from control and patients with type 2 diabetes.

ATP1A1 ATP1A2

1.34e-05374214685860
Pubmed

Na(+) pump alpha 2-isoform specifically couples to contractility in vascular smooth muscle: evidence from gene-targeted neonatal mice.

ATP1A1 ATP1A2

1.34e-05374214627611
Pubmed

Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.

ATP1A1 ATP1A3

1.34e-05374226988030
Pubmed

In situ localization of sodium-potassium ATPase mRNA in developing mouse lung epithelium.

ATP1A1 ATP1A2

1.34e-0537427573462
Pubmed

Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.

ATP1A1 ATP1A3

1.34e-05374227836549
Pubmed

Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.

ATP1A1 ATP1A3

1.34e-05374226373354
Pubmed

The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart.

ATP1A1 ATP1A2

1.34e-05374215485817
Pubmed

The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation.

ATP1A1 ATP1A2

1.34e-05374216243970
Pubmed

Na,K-ATPase subunit isoforms in human reticulocytes: evidence from reverse transcription-PCR for the presence of alpha1, alpha3, beta2, beta3, and gamma.

ATP1A1 ATP1A2

1.34e-0537429159180
Pubmed

Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes.

OR4F4 OR4F17

2.67e-0547429384599
Pubmed

Subunit isoform selectivity in assembly of Na,K-ATPase α-β heterodimers.

ATP1A1 ATP1A2

2.67e-05474222696220
Pubmed

Na,K-ATPase expression in the mouse cochlea is not dependent on the mineralocorticoid receptor.

ATP1A1 ATP1A3

2.67e-05474211591489
Pubmed

Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman.

ATP1A1 ATP1A2

2.67e-05474219570895
Pubmed

Coordinated regulation of cardiac Na(+)/Ca (2+) exchanger and Na (+)-K (+)-ATPase by phospholemman (FXYD1).

ATP1A1 ATP1A2

2.67e-05474223224879
Pubmed

Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.

ATP1A1 ATP1A3

2.67e-0547422887455
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP1A1 ATP1A2 ATP1A3

3.25e-052974315071553
Pubmed

Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes.

ATP1A1 ATP1A2 ATP1A3

3.60e-05307432842249
Pubmed

Thyrotoxic periodic paralysis and polymorphisms of sodium-potassium ATPase genes.

ATP1A1 ATP1A2

4.45e-05574216430714
Pubmed

Retinoschisin (RS1), the protein encoded by the X-linked retinoschisis gene, is anchored to the surface of retinal photoreceptor and bipolar cells through its interactions with a Na/K ATPase-SARM1 complex.

ATP1A2 ATP1A3

4.45e-05574217804407
Pubmed

Isoform-specific Na,K-ATPase and membrane cholesterol remodeling in motor endplates in distinct mouse models of myodystrophy.

ATP1A1 ATP1A2

4.45e-05574232293933
Pubmed

Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.

ATP1A1 ATP1A2

4.45e-05574216870707
Pubmed

Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.

ATP1A1 ATP1A2

4.45e-05574216292983
Pubmed

Systematic expression analysis of plasticity-related genes in mouse brain development brings PRG4 into play.

PLPPR4 PLPPR3

6.66e-05674234622503
Pubmed

Na,K-ATPase alpha- and beta-isoform expression in developing skeletal muscles: alpha(2) correlates with t-tubule formation.

ATP1A1 ATP1A2

6.66e-05674212397396
Pubmed

A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting.

PLPPR4 PLPPR3

6.66e-05674212730698
Pubmed

Endolymphatic Na⁺ and K⁺ concentrations during cochlear growth and enlargement in mice lacking Slc26a4/pendrin.

KCNQ1 ATP1A1

9.31e-05774223741519
Pubmed

TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis.

PLPPR4 PLPPR3

9.31e-05774222337885
Pubmed

Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.

OR4F5 OR4K2 OR14I1

1.31e-044674332126975
Pubmed

Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.

ATP1A1 ATP1A2 ATP1A3

1.69e-045074324769233
CytobandEnsembl 112 genes in cytogenetic band chr11q11

OR4P4 OR4C15 OR4S2 OR4C11 OR4C16

5.97e-0940745chr11q11
Cytoband11q11

OR4C15 OR4S2 OR4C11 OR4C16

1.05e-064774411q11
CytobandEnsembl 112 genes in cytogenetic band chr1q23

OR6N2 OR6K2 ATP1A2 OR10X1 PIGM

3.38e-05226745chr1q23
Cytoband15q26.3

OR4F4 OR4F15 OR4F6

4.10e-054174315q26.3
Cytoband1q23.1

OR6N2 OR6K2 OR10X1

5.81e-05467431q23.1
Cytoband14q11.2

OR4K2 OR4K13 OR4K5 OR4K15

2.12e-0418074414q11.2
Cytoband1q23.2

ATP1A2 PIGM

1.47e-03357421q23.2
Cytoband11q12.2

MS4A18 CYB561A3

1.83e-033974211q12.2
CytobandEnsembl 112 genes in cytogenetic band chr11p11

OR4C3 OR4C45 OR4C5

1.98e-03153743chr11p11
CytobandEnsembl 112 genes in cytogenetic band chr14q11

OR4K2 OR4K13 OR4K5 OR4K15

2.08e-03332744chr14q11
Cytoband11q12.1

OR4P4 SLC43A1 OR8K3

2.29e-0316174311q12.1
CytobandEnsembl 112 genes in cytogenetic band chr11q12

MS4A18 SLC43A1 OR8K3 CYB561A3

2.38e-03345744chr11q12
CytobandEnsembl 112 genes in cytogenetic band chr15q26

OR4F4 OR4F15 OR4F6

4.57e-03206743chr15q26
Cytoband11p11.2

OR4C3 OR4C5

8.02e-038374211p11.2
Cytoband17p13.3

OR3A1 OR1P1

8.97e-038874217p13.3
Cytoband1q21

ARNT SLC39A1

9.57e-03917421q21
GeneFamilyOlfactory receptors, family 4

OR4F5 OR4C3 OR4P4 OR4K2 OR4C15 OR4K13 OR4S2 OR4C11 OR4C16 OR4F4 OR4C45 OR4F17 OR4K5 OR4F21 OR4K15 OR4C5 OR4F15 OR4F6

1.33e-241296318151
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A1 ATP1A2 ATP1A3

1.40e-0676331208
GeneFamilyPhospholipid phosphatase related

PLPPR4 PLPPR3

1.19e-0456321127
GeneFamilyOlfactory receptors, family 14

OR14A2 OR14I1

2.48e-047632163
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_A

OR4C15 OR4F4 PCDH11Y OR8K3 OR4K5 OR4K15 OR4F15

1.11e-06210677MM958
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_A

OR4C15 OR4F4 OR8K3 OR4K5 OR4K15 OR4F15

1.04e-05194676M2517
CoexpressionACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN

OR4K2 OR4K13 OR4C16 PCDH11Y OR4K5 OR4K15

2.24e-05222676M16955
Drug22,23-dihydrobufalin

ATP1A1 ATP1A2 ATP1A3

2.65e-075693CID000195392
Drug3-acetylstrophanthin

ATP1A1 ATP1A2 ATP1A3

2.65e-075693CID003082282
Drugthevetin A

ATP1A1 ATP1A2 ATP1A3

2.65e-075693CID000441873
DrugETH157

ATP1A1 ATP1A2 ATP1A3

5.29e-076693CID000563154
Drugdihydrodigitoxigenin

ATP1A1 ATP1A2 ATP1A3

9.24e-077693CID000107549
DrugBepridil

KCNQ1 CACNA1H ATP1A1

1.48e-068693DB01244
Drugouabagenin

ATP1A1 ATP1A2 ATP1A3

4.32e-0611693CID000010497
DrugCID6432277

KCNQ1 ATP1A1 ATP1A2 ATP1A3

7.19e-0641694CID006432277
DrugA-32686

ATP1A1 ATP1A2 ATP1A3

7.45e-0613693CID000004951
DrugHDMA

ATP1A1 ATP1A2 ATP1A3

1.76e-0517693CID000131092
Drugamyl nitrite

SCNN1D ATP1A1 ATP1A2 ATP1A3

2.02e-0553694CID000008053
Drugacetylstrophanthidin

ATP1A1 ATP1A2 ATP1A3

2.10e-0518693CID000006062
DrugAC1L1F3Q

ATP1A1 ATP1A2 ATP1A3

2.10e-0518693CID000003068
DrugNSC 234205

ATP1A1 ATP1A2 ATP1A3

2.10e-0518693CID000010104
DrugCymarigenen

ATP1A1 ATP1A2 ATP1A3

2.93e-0520693CID000005303
DrugAC1NST54

ATP1A1 ATP1A2 ATP1A3

3.41e-0521693CID005315525
Drugcardenolide

ATP1A1 ATP1A2 ATP1A3

4.52e-0523693CID000016142
DrugAS701

ATP1A2 ATP1A3

5.41e-054692CID000133528
DrugNSC294864

ATP1A1 ATP1A2 ATP1A3 CYB561A3

7.98e-0575694CID000325714
Drugtrimethaphan

SCNN1D ATP1A1 ATP1A2 ATP1A3

1.08e-0481694CID000023576
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A1 ATP1A2 ATP1A3

2.78e-077603DOID:0060178 (implicated_via_orthology)
Diseasenervous system disease (implicated_via_orthology)

ATP1A1 ATP1A2 ATP1A3

1.74e-0612603DOID:863 (implicated_via_orthology)
Diseasesusceptibility to bacterial meningitis measurement

DPY19L2 PLPPR4 KCNQ1 SYS1

3.89e-0652604EFO_0008411
Diseasealternating hemiplegia of childhood (is_implicated_in)

ATP1A2 ATP1A3

4.07e-062602DOID:0050635 (is_implicated_in)
DiseaseALTERNATING HEMIPLEGIA OF CHILDHOOD 1

ATP1A2 ATP1A3

4.07e-062602C3549447
DiseaseAlternating hemiplegia of childhood

ATP1A2 ATP1A3

2.43e-054602C0338488
Diseasehyperhomocysteinemia (biomarker_via_orthology)

ATP1A1 ATP1A2

2.65e-0412602DOID:9279 (biomarker_via_orthology)
Diseasecardiac arrhythmia

PTCHD1 TBX5

1.71e-0330602EFO_0004269

Protein segments in the cluster

PeptideGeneStartEntry
GIFTFVDHRCVATVG

ARNT

371

P27540
GKTVQIIAFFAHLAC

EP400

1121

Q96L91
AGLIFVLHSCFRFIT

CMTR2

656

Q8IYT2
VLHSCFRFITFVCPT

CMTR2

661

Q8IYT2
TFFRVCLKHFQAVVS

DLL4

56

Q9NR61
FGERQCVFISKVVVH

PAAT

151

Q9H8K7
TCVSHFIVFSLFFGS

OR6K2

241

Q8NGY2
VGKSSIVCRFVQDHF

RAB31

16

Q13636
AFCFIAALVIFVTSV

OCLN

146

Q16625
SVHGQFRVATEKCLF

HIBCH

151

Q6NVY1
LAFVIVFEHVVFSVG

ANO7

851

Q6IWH7
TCASHLTVVIIHFGF

OR10X1

256

Q8NGY0
VISFGGCIAQIFFIH

OR4F21

91

O95013
SHIAVVILFFVPCIF

OR4C15

241

Q8NGM1
HFAVFLIVLVCLIFS

KCNQ1

126

P51787
RKIVEFTCHTAFFVS

ATP1A1

911

P05023
FTCHTAFFVSIVVVQ

ATP1A1

916

P05023
IVHAVLLGFVTVSCF

KCNK1

181

O00180
FVTFVLHTIVRGFFH

SLC43A1

446

O75387
ASHIFTVILFFVPCS

OR4C45

236

A6NMZ5
AFGTCVSHIGVVLAF

OR51E2

236

Q9H255
VFSTCVSHVGAVAFF

OR51F1

246

A6NGY5
LTQLFFFHLFVGVDC

OR3A1

101

P47881
FFHLFVGVDCFLLTA

OR3A1

106

P47881
HITVVLLFFGPCVFI

OR4F5

236

Q8NH21
TISFGGCVVQIFFIH

OR4F6

91

Q8NGB9
ALSTCTAHFIVVFLF

OR4K2

236

Q8NGD2
TAHFIVVFLFFGPCI

OR4K2

241

Q8NGD2
TISFSGCIAQIFFIH

OR4K5

91

Q8NGD3
SAHITVVTLFFAPCV

OR4K13

241

Q8NH42
TISFDACLAQIFFVH

OR4K15

91

Q8NH41
ACLAQIFFVHLFTGS

OR4K15

96

Q8NH41
ATCSSHVIVVVLFFA

OR4P4

236

Q8NGL7
GVHFFGCTEIFILTV

OR4S2

101

Q8NH73
DIISVLFIVAIFCFH

GDPD4

476

Q6W3E5
AISFRGCITQIFFSH

OR4F15

91

Q8NGB8
HITVVLLFFGPCVFI

OR4F17

236

Q8NGA8
SACTSHIIVVILFFG

OR4C11

236

Q6IEV9
ITVLCFFFNHGEATR

DPY19L2

276

Q6NUT2
VSAVTFSGIHLLRCF

GTPBP8

261

Q8N3Z3
LTVFAVCFVPFHITR

P2RY4

251

P51582
CASHLAVVLIFFGSI

OR6N2

241

Q8NGY6
VDCHVVPFSLFGKSF

CPT1C

541

Q8TCG5
EQRKVVEFTCHTAFF

ATP1A2

906

P50993
VEFTCHTAFFASIVV

ATP1A2

911

P50993
IIFVFLAETRFCHVV

EEF1AKMT2

246

Q5JPI9
FLSIVIVIFHCFAIQ

CNTN6

1011

Q9UQ52
FALLEFILTCVVSHF

MS4A18

261

Q3C1V0
RKVVEFTCHTAFFVS

ATP1A3

901

P13637
FTCHTAFFVSIVVVQ

ATP1A3

906

P13637
VIAFLGVLSCFHTAF

GPR85

96

P60893
FVLTVVGLVAVFTFH

CYB561A3

91

Q8NBI2
FDHVVLVFIFLNCVT

CACNA1H

1296

O95180
FFCTNATIHGAIRLV

SCNN1D

226

P51172
FFSFVCNSVVTIIHL

CALCRL

181

Q16602
DGKRVIVVFHCEFSS

CDC25A

421

P30304
STCVSHIIVVILFFG

OR4C16

236

Q8NGL9
IFAVLLVCVVFHSGA

PCDH11Y

41

Q9BZA8
FSTCDSHLVVVALFF

OR1P1

251

Q8NH06
FSTCFPHLTVFTVFI

OR14A2

236

Q96R54
HVLALVSCEVFFVEF

OR14I1

181

A6ND48
STCGAHFIVVALFFV

OR4C3

236

Q8NH37
HFIVVALFFVPCIFT

OR4C3

241

Q8NH37
STCAFHITVVVLFFV

OR4C5

251

Q8NGB2
VISFGGCIAQIFFIH

OR4F3;

91

Q6IEY1
HITVVLLFFGPCVFI

OR4F4

236

Q96R69
CLDFTVTVHFFHLLG

SYS1

91

Q8N2H4
FCTHVFPETAFIAVT

TBX5

201

Q99593
AFVTFFHCFAILPVI

PTCHD1

831

Q96NR3
FKFTIGDHSRFVNCV

WDR1

181

O75083
AFSTCGAHLTVVIVF

OR8K3

236

Q8NH51
VSLTCRFHVTVFKFI

TECTA

2016

O75443
VRFVGVHVFGLCSTA

PLPPR4

176

Q7Z2D5
VLTAAHCFFVTREKV

TMPRSS13

361

Q9BYE2
VRFVGVHVFGLCATA

PLPPR3

131

Q6T4P5
HFEAFGTLTDCVVVV

HNRNPA0

26

Q13151
KRHFVLVFVVFFICF

TMEM181

151

Q9P2C4
CVLVFSLALHSVFEG

SLC39A1

181

Q9NY26
TVRHCFFTVIFAIFS

RHBDD2

96

Q6NTF9
RDLVFCCFLHTSIFV

PIGM

311

Q9H3S5
FLTAFIFACVVTHLT

ZDHHC18

246

Q9NUE0
VFARGIAASGHFICV

WDR54

121

Q9H977
IFQTHKCVIVFGKFS

ZNF722

156

A0A1W2PQL4
VIVFRFFSICGKHVT

NALCN

1306

Q8IZF0