Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	ABCC4 ABCA1 MYO1C MYO6 MYO7B ABCA13 NAIP AK9 ATP8B1 ORC1 MDN1 MYO15A ATP1B3 DNAH6 DYNC1H1	5.30e-05	614	148	15	GO:0140657
GeneOntologyMolecularFunction	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	ALG10B ALG10	5.46e-05	2	148	2	GO:0106073
GeneOntologyMolecularFunction	microfilament motor activity	MYO1C MYO6 MYO7B MYO15A	1.76e-04	38	148	4	GO:0000146
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO1C MYO6 MYO7B MYO15A DNAH6 DYNC1H1	2.50e-04	118	148	6	GO:0003774
GeneOntologyCellularComponent	basal plasma membrane	ABCC4 ABCA1 MYO1C RASGRF1 NAIP CR1L MSN DST STXBP3 EGFR AGTR1 ATP1B3 SLC4A11	1.48e-06	354	148	13	GO:0009925
GeneOntologyCellularComponent	basal part of cell	ABCC4 ABCA1 MYO1C RASGRF1 NAIP CR1L MSN DST STXBP3 EGFR AGTR1 ATP1B3 SLC4A11	3.04e-06	378	148	13	GO:0045178
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	TMEM67 IFT140 TTLL3 GRIK2 OPA1 DST RP1L1 DNAH6 AP3D1 DYNC1H1 FBXW11	1.66e-05	317	148	11	GO:0032838
GeneOntologyCellularComponent	basolateral plasma membrane	ABCC4 ABCA1 RASGRF1 NAIP CR1L MSN STXBP3 EGFR AGTR1 ATP1B3 SLC4A11	1.81e-05	320	148	11	GO:0016323
GeneOntologyCellularComponent	cytoplasmic region	TMEM67 IFT140 TTLL3 GRIK2 OPA1 DST RP1L1 DNAH6 AP3D1 DYNC1H1 FBXW11	5.30e-05	360	148	11	GO:0099568
GeneOntologyCellularComponent	axon cytoplasm	OPA1 DST AP3D1 DYNC1H1 FBXW11	1.21e-04	68	148	5	GO:1904115
GeneOntologyCellularComponent	neuron projection cytoplasm	GRIK2 OPA1 DST AP3D1 DYNC1H1 FBXW11	1.33e-04	110	148	6	GO:0120111
GeneOntologyCellularComponent	actin-based cell projection	MYO1C MYO6 MYO7B ATP8B1 CUBN MSN MTM1 MYO15A DYNC1H1	1.67e-04	278	148	9	GO:0098858
GeneOntologyCellularComponent	myosin complex	MYO1C MYO6 MYO7B MYO15A	8.12e-04	59	148	4	GO:0016459
Domain	AAA	ABCC4 ABCA1 ABCA13 NAIP AK9 ORC1 MDN1 DNAH6 DYNC1H1	1.87e-06	144	145	9	SM00382
Domain	AAA+_ATPase	ABCC4 ABCA1 ABCA13 NAIP AK9 ORC1 MDN1 DNAH6 DYNC1H1	1.87e-06	144	145	9	IPR003593
Domain	MYTH4	MYO7B PLEKHH1 MYO15A	3.72e-05	9	145	3	PS51016
Domain	MyTH4	MYO7B PLEKHH1 MYO15A	3.72e-05	9	145	3	SM00139
Domain	MyTH4_dom	MYO7B PLEKHH1 MYO15A	3.72e-05	9	145	3	IPR000857
Domain	MyTH4	MYO7B PLEKHH1 MYO15A	3.72e-05	9	145	3	PF00784
Domain	Alg10	ALG10B ALG10	5.99e-05	2	145	2	IPR016900
Domain	Beta-TrCP_D	BTRC FBXW11	5.99e-05	2	145	2	IPR021977
Domain	Beta-TrCP_D	BTRC FBXW11	5.99e-05	2	145	2	PF12125
Domain	Beta-TrCP_D	BTRC FBXW11	5.99e-05	2	145	2	SM01028
Domain	DIE2_ALG10	ALG10B ALG10	5.99e-05	2	145	2	PF04922
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH6 DYNC1H1	1.57e-04	14	145	3	IPR011704
Domain	AAA_5	MDN1 DNAH6 DYNC1H1	1.57e-04	14	145	3	PF07728
Domain	Myosin_head_motor_dom	MYO1C MYO6 MYO7B MYO15A	2.10e-04	38	145	4	IPR001609
Domain	MYOSIN_MOTOR	MYO1C MYO6 MYO7B MYO15A	2.10e-04	38	145	4	PS51456
Domain	Myosin_head	MYO1C MYO6 MYO7B MYO15A	2.10e-04	38	145	4	PF00063
Domain	MYSc	MYO1C MYO6 MYO7B MYO15A	2.10e-04	38	145	4	SM00242
Domain	IQ	MYO1C RASGRF1 MYO6 MYO7B MYO15A	2.27e-04	71	145	5	PF00612
Domain	P-loop_NTPase	ABCC4 ABCA1 MYO1C MYO6 MYO7B ABCA13 APAF1 NAIP AK9 GTPBP1 OPA1 ORC1 MDN1 N4BP2 MYO15A DNAH6 DYNC1H1	3.17e-04	848	145	17	IPR027417
Domain	PP2A_PR55_CS	PPP2R2D PPP2R2B	3.56e-04	4	145	2	IPR018067
Domain	PP2A_PR55	PPP2R2D PPP2R2B	3.56e-04	4	145	2	IPR000009
Domain	PR55_2	PPP2R2D PPP2R2B	3.56e-04	4	145	2	PS01025
Domain	PR55_1	PPP2R2D PPP2R2B	3.56e-04	4	145	2	PS01024
Domain	IQ	MYO1C RASGRF1 MYO6 MYO7B MYO15A	4.20e-04	81	145	5	SM00015
Domain	FERM_M	MYO7B MSN PLEKHH1 MYO15A	4.41e-04	46	145	4	PF00373
Domain	FERM_central	MYO7B MSN PLEKHH1 MYO15A	5.63e-04	49	145	4	IPR019748
Domain	FERM_domain	MYO7B MSN PLEKHH1 MYO15A	5.63e-04	49	145	4	IPR000299
Domain	FERM_1	MYO7B MSN PLEKHH1 MYO15A	6.08e-04	50	145	4	PS00660
Domain	FERM_2	MYO7B MSN PLEKHH1 MYO15A	6.08e-04	50	145	4	PS00661
Domain	FERM_3	MYO7B MSN PLEKHH1 MYO15A	6.08e-04	50	145	4	PS50057
Domain	Band_41_domain	MYO7B MSN PLEKHH1 MYO15A	6.08e-04	50	145	4	IPR019749
Domain	B41	MYO7B MSN PLEKHH1 MYO15A	6.08e-04	50	145	4	SM00295
Domain	IQ_motif_EF-hand-BS	MYO1C RASGRF1 MYO6 MYO7B MYO15A	6.81e-04	90	145	5	IPR000048
Domain	-	ABCC4 ABCA1 MYO7B ABCA13 APAF1 NAIP AK9 GTPBP1 OPA1 ORC1 MDN1 N4BP2 MYO15A DNAH6 DYNC1H1	7.03e-04	746	145	15	3.40.50.300
Domain	IQ	MYO1C RASGRF1 MYO6 MYO7B MYO15A	7.91e-04	93	145	5	PS50096
Domain	-	SEMA4D IFT140 PPP2R2D APAF1 PPP2R2B SEMA4A BTRC RIC1 FBXW11	1.19e-03	333	145	9	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEMA4D IFT140 PPP2R2D APAF1 PPP2R2B SEMA4A BTRC RIC1 FBXW11	1.24e-03	335	145	9	IPR015943
Domain	Plexin_repeat	SEMA4D ATRNL1 SEMA4A	1.93e-03	32	145	3	IPR002165
Domain	PSI	SEMA4D ATRNL1 SEMA4A	1.93e-03	32	145	3	PF01437
Domain	RNaseH-like_dom	ZNF618 ESRP1 FAM200A PIWIL3	2.04e-03	69	145	4	IPR012337
Domain	HEAT_REPEAT	SMG1 HEATR1 ECPAS AP3D1	2.15e-03	70	145	4	PS50077
Domain	CENP-B_N	TIGD1 JRKL	2.59e-03	10	145	2	PF04218
Domain	ABC_A	ABCA1 ABCA13	3.75e-03	12	145	2	IPR026082
Domain	HTH_Psq	TIGD1 JRKL	3.75e-03	12	145	2	IPR007889
Domain	HTH_PSQ	TIGD1 JRKL	3.75e-03	12	145	2	PS50960
Domain	CENPB	TIGD1 JRKL	3.75e-03	12	145	2	SM00674
Domain	DDE_1	TIGD1 JRKL	3.75e-03	12	145	2	PF03184
Domain	DDE_SF_endonuclease_dom	TIGD1 JRKL	3.75e-03	12	145	2	IPR004875
Domain	HTH_CENPB	TIGD1 JRKL	4.41e-03	13	145	2	PS51253
Domain	HTH_Tnp_Tc5	TIGD1 JRKL	4.41e-03	13	145	2	PF03221
Domain	TTL	TTLL3 TTLL11	4.41e-03	13	145	2	PS51221
Domain	TTL/TTLL_fam	TTLL3 TTLL11	4.41e-03	13	145	2	IPR004344
Domain	HTH_CenpB_DNA-bd_dom	TIGD1 JRKL	4.41e-03	13	145	2	IPR006600
Domain	TTL	TTLL3 TTLL11	4.41e-03	13	145	2	PF03133
Domain	PSI	SEMA4D ATRNL1 SEMA4A	4.81e-03	44	145	3	IPR016201
Domain	Dynein_heavy_chain_D4_dom	DNAH6 DYNC1H1	5.12e-03	14	145	2	IPR024317
Domain	Dynein_HC_stalk	DNAH6 DYNC1H1	5.12e-03	14	145	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH6 DYNC1H1	5.12e-03	14	145	2	IPR013602
Domain	DHC_N2	DNAH6 DYNC1H1	5.12e-03	14	145	2	PF08393
Domain	MT	DNAH6 DYNC1H1	5.12e-03	14	145	2	PF12777
Domain	AAA_8	DNAH6 DYNC1H1	5.12e-03	14	145	2	PF12780
Domain	PSI	SEMA4D ATRNL1 SEMA4A	5.45e-03	46	145	3	SM00423
Domain	DHC_fam	DNAH6 DYNC1H1	5.88e-03	15	145	2	IPR026983
Domain	Dynein_heavy	DNAH6 DYNC1H1	5.88e-03	15	145	2	PF03028
Domain	PI3/4_kinase_CS	SMG1 PIK3CG	5.88e-03	15	145	2	IPR018936
Domain	Dynein_heavy_dom	DNAH6 DYNC1H1	5.88e-03	15	145	2	IPR004273
Domain	WD_REPEATS_1	IFT140 PPP2R2D APAF1 PPP2R2B BTRC RIC1 FBXW11	6.07e-03	278	145	7	PS00678
Domain	ABC_tran	ABCC4 ABCA1 ABCA13	6.14e-03	48	145	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCC4 ABCA1 ABCA13	6.14e-03	48	145	3	PS50893
Domain	WD_REPEATS_2	IFT140 PPP2R2D APAF1 PPP2R2B BTRC RIC1 FBXW11	6.19e-03	279	145	7	PS50082
Domain	WD_REPEATS_REGION	IFT140 PPP2R2D APAF1 PPP2R2B BTRC RIC1 FBXW11	6.19e-03	279	145	7	PS50294
Domain	-	MYO7B MSN PLEKHH1	6.50e-03	49	145	3	1.20.80.10
Domain	ABC_TRANSPORTER_1	ABCC4 ABCA1 ABCA13	6.50e-03	49	145	3	PS00211
Domain	-	SMG1 PIK3CG	6.69e-03	16	145	2	1.10.1070.11
Domain	PI3Kc	SMG1 PIK3CG	6.69e-03	16	145	2	SM00146
Domain	FERM/acyl-CoA-bd_prot_3-hlx	MYO7B MSN PLEKHH1	6.88e-03	50	145	3	IPR014352
Domain	ABC_transporter-like	ABCC4 ABCA1 ABCA13	6.88e-03	50	145	3	IPR003439
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	SMG1 MYO1C RSL1D1 APAF1 PRPF6 HEATR1 GTPBP1 ECPAS MYEF2 MSN PPP2R2B DST STXBP3 PPIP5K2	4.20e-08	498	151	14	36634849
Pubmed	Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells.	EGFR TLR3 MUC5AC	8.02e-08	3	151	3	26100173
Pubmed	Rhinovirus-induced major airway mucin production involves a novel TLR3-EGFR-dependent pathway.	EGFR TLR3 MUC5AC	8.02e-08	3	151	3	18978302
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MAPKAP1 SMG1 USP13 SCAF8 SAMD4B UTP14A GTPBP1 ALG10B MSN DST PPIP5K2 HSD17B11 SEC61A1 AP3D1 RIC1	1.75e-07	650	151	15	38777146
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYO1C RSL1D1 UTP14A PRPF6 HEATR1 ECPAS PAICS MYEF2 MSN GTF2I DST MDN1 DYNC1H1 PTCD3	1.10e-06	653	151	14	22586326
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	SETD1B PPP2R2D RSL1D1 SCAF8 ZC3H15 GRIK2 MYEF2 MSN LRRC8B AP3D1 BTRC FBXW11	1.24e-06	475	151	12	31040226
Pubmed	Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis.	IFNAR1 BTRC FBXW11	1.59e-06	6	151	3	18056411
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	MYO6 RSL1D1 AK9 PRPF6 ECPAS PAICS OPA1 MDN1 XIRP2 TAOK1 AP3D1 RIC1	1.98e-06	497	151	12	36774506
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	MYO6 RSL1D1 PRPF6 HEATR1 PARP14 SQOR OPA1 MDN1 AP3D1	2.37e-06	262	151	9	36880596
Pubmed	Tails of unconventional myosins.	MYO6 MYO7B MYO15A	2.77e-06	7	151	3	11212352
Pubmed	Myosins: a diverse superfamily.	MYO1C MYO6 MYO15A	2.77e-06	7	151	3	10722873
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SETD1B MYO1C MYO6 RSL1D1 UTP14A PRPF6 HEATR1 RRM1 PAICS MYEF2 MSN ORC1 GTF2I DST MDN1 AP3D1 BTRC DYNC1H1 PTCD3	6.94e-06	1353	151	19	29467282
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MAPKAP1 MYO6 RSL1D1 ZC3H15 UTP14A APAF1 PRPF6 HEATR1 TNFRSF10B RRM1 MDN1 STXBP3 EGFR ERAP2 N4BP2 TMEM131L ATP1B3 SEC61A1 AP3D1 PTCD3	7.37e-06	1487	151	20	33957083
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MYO1C MYO6 RSL1D1 SAMD4B PRPF6 HEATR1 ECPAS QRICH2 PAICS OPA1 MSN USP8 GTF2I ATP1B3 SEC61A1 DYNC1H1 FBXW11 PTCD3	1.26e-05	1284	151	18	17353931
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SEMA4D USP13 MYO6 RSL1D1 CEP290 ARMCX4 PAICS PLEKHH1 USP8 DST ATRNL1 MTM1 TAOK1 ANKRD36 BTRC MED13 DYNC1H1 FBXW11	1.28e-05	1285	151	18	35914814
Pubmed	Defining the membrane proteome of NK cells.	ABCC4 MYO1C MYO6 CEP290 PRPF6 HEATR1 GTPBP1 ECPAS PARP14 PAICS OPA1 GTF2I MDN1 PIK3CG AP3D1 MED13 DYNC1H1	1.39e-05	1168	151	17	19946888
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MYO1C MYO6 RSL1D1 ZC3H15 UTP14A PRPF6 HEATR1 GTPBP1 ECPAS PAICS OPA1 GTF2I MDN1 STXBP3 TDRD6 ATP1B3 SEC61A1 DYNC1H1 PTCD3	1.44e-05	1425	151	19	30948266
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	FCRL2 SEMA4D MYO7B PRPF6 TNFRSF10B IFNAR1 PPP2R2B BPHL PIK3CG TLR3 SEMA4A SLAMF7 EPHX4 IL17RB	1.56e-05	824	151	14	20237496
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	SMG1 MYO1C RSL1D1 PRPF6 HEATR1 RRM1 ECPAS PAICS AFAP1 GTF2I DST MDN1 ATP1B3 SEC61A1 AP3D1 BTRC DYNC1H1 FBXW11 PTCD3	1.66e-05	1440	151	19	30833792
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	ZNF618 RTTN PARP14 DST ANKRD36 DNAH6 MUC5AC	1.87e-05	187	151	7	26460568
Pubmed	Increased expression of mucin 5AC mRNA and decreased expression of epidermal growth-factor receptor mRNA in gallstone patients.	EGFR MUC5AC	1.87e-05	2	151	2	18285671
Pubmed	Synergy of epidermal growth factor (EGFR) and angiotensin II (AT1R) receptor determines composition and temporal pattern of transcriptome variation.	EGFR AGTR1	1.87e-05	2	151	2	34921637
Pubmed	S1PR1-mediated IFNAR1 degradation modulates plasmacytoid dendritic cell interferon-α autoamplification.	S1PR1 IFNAR1	1.87e-05	2	151	2	26787880
Pubmed	MYLK4 promotes tumor progression through the activation of epidermal growth factor receptor signaling in osteosarcoma.	EGFR MYLK4	1.87e-05	2	151	2	33980265
Pubmed	Moesin controls clathrin-mediated S1PR1 internalization in T cells.	S1PR1 MSN	1.87e-05	2	151	2	24358210
Pubmed	The characteristics and roles of β-TrCP1/2 in carcinogenesis.	BTRC FBXW11	1.87e-05	2	151	2	33021036
Pubmed	The role of EGFR in vascular AT1R signaling: From cellular mechanisms to systemic relevance.	EGFR AGTR1	1.87e-05	2	151	2	37777161
Pubmed	Specificity, location and function of βTrCP isoforms and their splice variants.	BTRC FBXW11	1.87e-05	2	151	2	21138764
Pubmed	MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder.	EGFR MUC5AC	1.87e-05	2	151	2	17148666
Pubmed	Depletion of the 26S proteasome adaptor Ecm29 increases Toll-like receptor 3 signaling.	ECPAS TLR3	1.87e-05	2	151	2	24084648
Pubmed	Semaphorins 4A and 4D in chronic inflammatory diseases.	SEMA4D SEMA4A	1.87e-05	2	151	2	27554682
Pubmed	Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-κB and EGFR pathways.	EGFR MUC5AC	1.87e-05	2	151	2	20525715
Pubmed	Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes.	USP8 EGFR	1.87e-05	2	151	2	16120644
Pubmed	Ubiquitin-specific protease 8 is a novel prognostic marker in early-stage lung adenocarcinoma.	USP8 EGFR	1.87e-05	2	151	2	28544031
Pubmed	Phosphorylation of tyrosine 319 of the angiotensin II type 1 receptor mediates angiotensin II-induced trans-activation of the epidermal growth factor receptor.	EGFR AGTR1	1.87e-05	2	151	2	12522132
Pubmed	Integrity of ATP binding site is essential for effective inhibition of the intrinsic apoptosis pathway by NAIP.	APAF1 NAIP	1.87e-05	2	151	2	21371431
Pubmed	Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1.	RASGRF1 USP8	1.87e-05	2	151	2	11500497
Pubmed	Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Growth of Gefitinib-resistant Non-small Cell Lung Cancer Cells by Inducing Apoptosis.	USP8 EGFR	1.87e-05	2	151	2	25853104
Pubmed	UBPY-mediated epidermal growth factor receptor (EGFR) de-ubiquitination promotes EGFR degradation.	USP8 EGFR	1.87e-05	2	151	2	17121848
Pubmed	EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.	USP8 EGFR	1.87e-05	2	151	2	29472535
Pubmed	[Roles of epidermal growth factor receptor signaling pathway on cultured human nasal epithelial cells RPMI-2650].	EGFR MUC5AC	1.87e-05	2	151	2	19558858
Pubmed	Differential dysregulation of β-TrCP1 and -2 by HIV-1 Vpu leads to inhibition of canonical and non-canonical NF-κB pathways in infected cells.	BTRC FBXW11	1.87e-05	2	151	2	37341489
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	MYO1C MYO6 PAICS GTF2I DST EGFR DYNC1H1	2.14e-05	191	151	7	33762435
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 IFT140 PPP2R2D ECPAS MYEF2 AFAP1 DST TMEM131L DEPDC5 PPIP5K2 MED13	2.15e-05	529	151	11	14621295
Pubmed	MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.	USP8 RNF139 BTRC FBXW11	2.76e-05	40	151	4	30759391
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MYO1C MYO6 RSL1D1 ZC3H15 UTP14A PRPF6 HEATR1 GTPBP1 SQOR PAICS MSN AFAP1 GTF2I DST EGFR DYNC1H1 PTCD3	3.51e-05	1257	151	17	36526897
Pubmed	PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis.	RSL1D1 UTP14A HEATR1 MSN GTF2I	4.71e-05	90	151	5	30699358
Pubmed	The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth.	BTRC FBXW11	5.60e-05	3	151	2	31406304
Pubmed	Recurrent gain-of-function USP8 mutations in Cushing's disease.	USP8 EGFR	5.60e-05	3	151	2	25675982
Pubmed	A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).	ALG10B ALG10	5.60e-05	3	151	2	24303013
Pubmed	MUC5AC expression through bidirectional communication of Notch and epidermal growth factor receptor pathways.	EGFR MUC5AC	5.60e-05	3	151	2	21622856
Pubmed	Epidermal growth factor receptor-PI3K signaling controls cofilin activity to facilitate herpes simplex virus 1 entry into neuronal cells.	EGFR PIK3CG	5.60e-05	3	151	2	24425731
Pubmed	Transcription factor AP-1 promotes growth and radioresistance in prostate cancer cells.	EGFR PIK3CG	5.60e-05	3	151	2	19787273
Pubmed	SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.	BTRC FBXW11	5.60e-05	3	151	2	18354483
Pubmed	CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs.	S1PR1 IFNAR1	5.60e-05	3	151	2	16525420
Pubmed	The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2.	BTRC FBXW11	5.60e-05	3	151	2	18782782
Pubmed	Immunoadjuvant effects of polyadenylic:polyuridylic acids through TLR3 and TLR7.	IFNAR1 TLR3	5.60e-05	3	151	2	17981792
Pubmed	Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor.	EGFR AGTR1	5.60e-05	3	151	2	15545271
Pubmed	Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8.	USP8 EGFR	5.60e-05	3	151	2	20064931
Pubmed	The ubiquitin ligase subunit β-TrCP in Sertoli cells is essential for spermatogenesis in mice.	BTRC FBXW11	5.60e-05	3	151	2	30391586
Pubmed	Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.	EGFR PIK3CG	5.60e-05	3	151	2	19229860
Pubmed	Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2.	SEMA4D SEMA4A	5.60e-05	3	151	2	12374982
Pubmed	Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2.	IFNAR1 BTRC	5.60e-05	3	151	2	21173164
Pubmed	Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP.	ABCA1 OSBP	5.60e-05	3	151	2	29540530
Pubmed	Persistent stimulation with interleukin-17 desensitizes cells through SCFβ-TrCP-mediated degradation of Act1.	BTRC FBXW11	5.60e-05	3	151	2	22045853
Pubmed	Dendritic cell maturation, but not CD8+ T cell induction, is dependent on type I IFN signaling during vaccination with adenovirus vectors.	IFNAR1 TLR3	5.60e-05	3	151	2	16237098
Pubmed	ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP.	IFNAR1 BTRC	5.60e-05	3	151	2	30988430
Pubmed	Phosphorylation and specific ubiquitin acceptor sites are required for ubiquitination and degradation of the IFNAR1 subunit of type I interferon receptor.	IFNAR1 FBXW11	5.60e-05	3	151	2	15337770
Pubmed	Semaphorin 4A, 4C, and 4D: Function comparison in the autoimmunity, allergy, and cancer.	SEMA4D SEMA4A	5.60e-05	3	151	2	32244055
Pubmed	Activation of the RIG-I pathway during influenza vaccination enhances the germinal center reaction, promotes T follicular helper cell induction, and provides a dose-sparing effect and protective immunity.	IFNAR1 TLR3	5.60e-05	3	151	2	25253340
Pubmed	The sex distribution of waved-2, shaker-2 and Rex in the house mouse.	EGFR MYO15A	5.60e-05	3	151	2	13170359
Pubmed	Stability of Wake-Sleep Cycles Requires Robust Degradation of the PERIOD Protein.	BTRC FBXW11	5.60e-05	3	151	2	29103939
Pubmed	Toll-Like Receptor 3 Mediates Aortic Stenosis Through a Conserved Mechanism of Calcification.	IFNAR1 TLR3	5.60e-05	3	151	2	37013819
Pubmed	Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase.	BTRC FBXW11	5.60e-05	3	151	2	23640883
Pubmed	Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners.	EGFR AGTR1	5.60e-05	3	151	2	33741329
Pubmed	Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus.	IFNAR1 TLR3	5.60e-05	3	151	2	17502662
Pubmed	Linkage of open eyelids with linkage group VII of the mouse.	EGFR MYO15A	5.60e-05	3	151	2	5690495
Pubmed	Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway.	PIK3CG AGTR1	5.60e-05	3	151	2	20458733
Pubmed	Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.	MYO6 EGFR	5.60e-05	3	151	2	20604900
Pubmed	Silencing of both beta-TrCP1 and HOS (beta-TrCP2) is required to suppress human immunodeficiency virus type 1 Vpu-mediated CD4 down-modulation.	BTRC FBXW11	5.60e-05	3	151	2	17121803
Pubmed	ABC transporters as differentiation markers in glioblastoma cells.	ABCC4 ABCA1	5.60e-05	3	151	2	25028266
Pubmed	Degradation of human Lipin-1 by BTRC E3 ubiquitin ligase.	BTRC FBXW11	5.60e-05	3	151	2	28483528
Pubmed	Critical role for IL-1β in DNA damage-induced mucositis.	BTRC FBXW11	5.60e-05	3	151	2	24469832
Pubmed	Prospective Evaluation of Kidney Disease in Joubert Syndrome.	TMEM67 CEP290	5.60e-05	3	151	2	29146704
Pubmed	A novel function of angiotensin II in skin wound healing. Induction of fibroblast and keratinocyte migration by angiotensin II via heparin-binding epidermal growth factor (EGF)-like growth factor-mediated EGF receptor transactivation.	EGFR AGTR1	5.60e-05	3	151	2	16543233
Pubmed	MicroRNA-145 down-regulates mucin 5AC to alleviate airway remodeling and targets EGFR to inhibit cytokine expression.	EGFR MUC5AC	5.60e-05	3	151	2	28564633
Pubmed	Impaired endocytosis in proximal tubule from subchronic exposure to cadmium involves angiotensin II type 1 and cubilin receptors.	CUBN AGTR1	5.60e-05	3	151	2	24093454
Pubmed	Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome.	TMEM67 CEP290	5.60e-05	3	151	2	18327255
Pubmed	OSBP negatively regulates ABCA1 protein stability.	ABCA1 OSBP	5.60e-05	3	151	2	18450749
Pubmed	Novel myosin mutations for hereditary hearing loss revealed by targeted genomic capture and massively parallel sequencing.	MYO6 MYO15A	5.60e-05	3	151	2	24105371
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MYO6 ZC3H15 RRM1 ECPAS PAICS OPA1 MSN DST EGFR ATP1B3 AP3D1 DYNC1H1	6.59e-05	708	151	12	39231216
Pubmed	The sequence of the human genome.	SEMA4D MYO7B AK9 ARMCX4 RFX8 SCNN1B TDRD6 CCDC180 DNAH6 MUC5AC TMEM191A	7.01e-05	603	151	11	11181995
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	IFT140 UTP14A GTF2I ARIH1 BTRC DYNC1H1 FBXW11	7.34e-05	232	151	7	25515538
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TTLL3 RSL1D1 UTP14A ESRP1 HEATR1 CUBN PAICS RESF1 ATRNL1 HPS1 TMEM131L SLC35F2 TAOK1 IPMK TGS1	8.05e-05	1084	151	15	11544199
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	SMG1 RSL1D1 UTP14A TIGD1 PARP14 OPA1 DST JRKL PTCD3	8.15e-05	410	151	9	26949251
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SEMA4D ABCC4 TTLL3 MYO6 SCAF8 SAMD4B NAIP GRIK2 ATP8B1 ECPAS PLEKHH1 GTF2I EGFR TTLL11 SLC35F2 ARIH1 RIC1 FBXW11	8.65e-05	1489	151	18	28611215
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	MYO6 CEP290 ECPAS MDN1 DYNC1H1	9.39e-05	104	151	5	9205841
Pubmed	Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo.	USP8 EGFR	1.12e-04	4	151	2	17452457
Pubmed	A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity.	IFNAR1 TLR3	1.12e-04	4	151	2	19074283
Pubmed	S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.	BTRC FBXW11	1.12e-04	4	151	2	26240281
GeneFamily	Alpha-1,2-glucosyltransferases	ALG10B ALG10	3.03e-05	2	100	2	448
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	MYO7B MSN PLEKHH1 MYO15A	1.67e-04	50	100	4	1293
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	BTRC FBXW11	1.61e-03	11	100	2	559
GeneFamily	Helix-turn-helix CENPB type domain containing	TIGD1 JRKL	2.27e-03	13	100	2	533
GeneFamily	Tubulin tyrosine ligase family	TTLL3 TTLL11	2.64e-03	14	100	2	779
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA13	2.64e-03	14	100	2	805
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R2D PPP2R2B	3.03e-03	15	100	2	696
GeneFamily	WD repeat domain containing	IFT140 PPP2R2D APAF1 PPP2R2B BTRC FBXW11	3.35e-03	262	100	6	362
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	SMG1 TNFRSF10B PIK3CG TAOK1 VWA3B DEPDC5 MED13 IL17RB RIC1	1.01e-06	180	150	9	M8239
Coexpression	SENESE_HDAC3_TARGETS_UP	MAPKAP1 SMG1 ABCC4 MYO6 PRPF6 HEATR1 TNFRSF10B GTF2I DST PTX3 TAOK1 SEC61A1 FBXW11	5.80e-06	495	150	13	M8451
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	USP13 SCAF8 ATP8B1 OPA1 TGFBR3 AFAP1 DST MDN1 STXBP3 EGFR PTX3 TMEM131L ARIH1 PPIP5K2 BTRC MED13 FBXW11	8.68e-06	856	150	17	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN	ATP8B1 TGFBR3 DST PTX3 TMEM131L BTRC	9.58e-06	85	150	6	M10575
Coexpression	SENESE_HDAC1_TARGETS_UP	ABCC4 MYO6 PRPF6 TNFRSF10B GTF2I RESF1 PTX3 TAOK1 CARNMT1 SLAMF7 SEC61A1 FBXW11	1.18e-05	451	150	12	M14973
Coexpression	GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN	IFT140 PPP2R2D TGFBR3 GTF2I MDN1 SEMA4A HSD17B11 RIC1	2.01e-05	199	150	8	M4331
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000	SMG1 APAF1 HEATR1 RRM1 ECPAS MYEF2 RESF1 TAOK1 SEC61A1 MED13 FBXW11 TGS1	1.87e-05	397	145	12	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	MAPKAP1 ABCC4 EGFR VWA3B TDRD6 MYO15A ADGRF1 DNAH6 SLC4A11	2.40e-08	197	150	9	6b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	C14orf93 ARMCX4 ALG10B OSBP ALG10 TLR3 TMEM131L BTRC	2.15e-07	184	150	8	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMG1 PARP14 TMEM131L TAOK1 ANKRD36 ARIH1 MED13 DYNC1H1	2.54e-07	188	150	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 ORC1 MALRD1 EGFR TTLL11 TAOK1 IL17RB	8.59e-07	152	150	7	7a1072315cce71eefe2d32149a107d5648999968
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Npnt_(Layer_5a)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	STRA8 RFX8 ORC1 ADGRF1 DNAH6	1.28e-06	56	150	5	112a412816287423089c0333a42432a6ab4500dc
ToppCell	RSV-Healthy-5\|Healthy / Virus stimulation, Condition and Cluster	PRPF6 CCDC141 S1PR1 LRRN3 ANKRD18A DNAH6 SLC4A11	3.07e-06	184	150	7	1e282d619ef8035437fabe0fd2aefda1c142f7f6
ToppCell	RSV-Healthy-5\|RSV / Virus stimulation, Condition and Cluster	PRPF6 CCDC141 S1PR1 LRRN3 ANKRD18A DNAH6 SLC4A11	3.07e-06	184	150	7	ba958f731de6c9eff60103d483e020e2c0c7af7c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 PLEKHH1 SCNN1B ANKRD18A ANKRD36 MUC5AC SLC4A11	3.07e-06	184	150	7	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	C14orf93 ARMCX4 ALG10B OSBP ALG10 TLR3 TMEM131L	3.18e-06	185	150	7	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	TCEA3 TTLL3 CEP290 AK9 BPHL CCDC180 DNAH6	3.54e-06	188	150	7	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCEA3 TTLL3 CEP290 AK9 BPHL CCDC180 DNAH6	4.06e-06	192	150	7	b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCell	PND03-Epithelial-Epithelial_Airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCEA3 TTLL3 CEP290 AK9 BPHL CCDC180 DNAH6	4.06e-06	192	150	7	2d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ALG10B USP8 N4BP2 TAOK1 LRRC8B MED13 DYNC1H1	4.20e-06	193	150	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCC4 ABCA13 GRIK2 PLEKHH1 SCNN1B MUC5AC SLC4A11	4.50e-06	195	150	7	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 CEP290 AK9 MYEF2 VWA3B CCDC180 DNAH6	4.81e-06	197	150	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Mild/Remission-Developping_Plasmablast\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RRM1 ORC1 CKAP2L SEMA4A SLAMF7 SEC61A1 MYBL2	5.14e-06	199	150	7	58c772ec763109a4009f52424fbb214fc23d0c09
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TNFRSF10B AFAP1 ADGRF1 MUC5AC JRKL SLC4A11 PDE11A	5.31e-06	200	150	7	1b527bebbca1ef8c52449e40beb9358e37494e04
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ORC1 MALRD1 DST EGFR TTLL11 IL17RB	1.39e-05	154	150	6	6c1e7682c43c40b58b371c58deb10b839700ebcc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RRM1 ORC1 FANCB CKAP2L IL17RB MYBL2	1.50e-05	156	150	6	955547dfeb1b1ad4957b4338701055726b22619f
ToppCell	mild_COVID-19_(asymptomatic)-Plasmablast\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	QRICH2 ORC1 SCNN1B CKAP2L SLC35F2 MYBL2	2.12e-05	166	150	6	0cc3b9681bc000a1b00d3b60f79f16eea1c2e2e1
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FCRL2 RASGRF1 ADAM32 QRICH2 ANKRD36 SEMA4A	2.68e-05	173	150	6	77e2b2e66c89984769f2800bdeeab42f9cf9fc46
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	SMG1 SCAF8 HEATR1 PARP14 DST ALG10	2.95e-05	176	150	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RRM1 ALG10B AFAP1 SLC35F2 SEMA4A MYBL2	3.05e-05	177	150	6	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMG1 ABCA13 PLEKHH1 ADGRF1 MUC5AC SLC4A11	3.25e-05	179	150	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Basal\|World / shred by cell class for mouse tongue	ABCA1 RAPSN PAICS MSN AFAP1 DST	3.67e-05	183	150	6	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	RASGRF1 MYO6 ESRP1 CCDC141 EGFR ADGRF1	3.79e-05	184	150	6	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	TCEA3 TLCD4 RRM1 MALRD1 CKAP2L MYBL2	4.02e-05	186	150	6	189b75aa98903f1cb65b624524ba6c30df7e42ff
ToppCell	356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|356C / Donor, Lineage, Cell class and subclass (all cells)	TCEA3 TLCD4 RRM1 MALRD1 CKAP2L MYBL2	4.02e-05	186	150	6	261891d0b148e285339ae0b9e36136ceabd9b6f5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCC4 MYO6 ABCA13 TNFRSF10B ADGRF1 AP3D1	4.02e-05	186	150	6	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SCNN1B SLC35F2 SEMA4A SLAMF7 SEC61A1 MYBL2	4.14e-05	187	150	6	88d20f150df61ef0e3ee0c3e9895b094920c4b09
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RFX8 PARP14 ORC1 C12orf54 SLC35F2 SLAMF7	4.14e-05	187	150	6	a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCEA3 CEP290 AK9 BPHL CCDC180 DNAH6	4.40e-05	189	150	6	fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D ABCC4 ABCA13 EGFR DNAH6 SLC4A11	4.40e-05	189	150	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	Severe_COVID-19-Epithelial-undefined_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MYO6 MYEF2 ADGRF1 MUC5AC SLC4A11 MYBL2	4.40e-05	189	150	6	8cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCEA3 CEP290 AK9 BPHL CCDC180 DNAH6	4.40e-05	189	150	6	565063f9e3dd79164321f8a394bd12c176baf202
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCEA3 CEP290 AK9 BPHL CCDC180 DNAH6	4.40e-05	189	150	6	497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	NAIP S1PR1 MYEF2 N4BP2 ALG10 TLR3	4.53e-05	190	150	6	2434b8ad2976eab7d9147012c28454ab29670709
ToppCell	368C-Epithelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 RASGRF1 ESRP1 CCDC141 SCNN1B ADGRF1	4.53e-05	190	150	6	459811e88d3001816c2d89034e0921c24918c17f
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCEA3 TTLL3 CEP290 AK9 CCDC180 DNAH6	4.66e-05	191	150	6	bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCEA3 TTLL3 CEP290 AK9 CCDC180 DNAH6	4.66e-05	191	150	6	6880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NAIP S1PR1 MYEF2 N4BP2 ALG10 TLR3	4.66e-05	191	150	6	39ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic-lymphocyte-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RFX8 RRM1 ORC1 SCNN1B CKAP2L MYBL2	4.66e-05	191	150	6	56b45259dfc38bd5ea43b0e3adf47e7e2c043a5d
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAPOR2 ABCA1 RASGRF1 ATP8B1 DST SCNN1B	4.80e-05	192	150	6	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ELAPOR2 ABCC4 RASGRF1 MYO6 ESRP1 CCDC141	4.80e-05	192	150	6	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	Monocytes-Tissue-resident_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	ABCC4 INAFM2 ZNF618 DST TLR3 ANKRD36	4.94e-05	193	150	6	198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FCRL2 TMEM67 MYO1C PARP14 CCDC141 TMEM131L	5.08e-05	194	150	6	d852aebf7a763b9a776c4570711f0c759f591910
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 ABCA13 AK9 ANKRD18A CCDC180 DNAH6	5.08e-05	194	150	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 ABCA13 AK9 VWA3B CCDC180 DNAH6	5.23e-05	195	150	6	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	CV-Severe-6\|CV / Virus stimulation, Condition and Cluster	RASGEF1A SQOR TGFBR3 RESF1 SLAMF7 ATP1B3	5.23e-05	195	150	6	69095c6ce2a7e763afa543c10d5710e0c3dda769
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FCRL2 ERAP2 PIK3CG DEPDC5 SLAMF7 MYBL2	5.23e-05	195	150	6	c6e31038be2463f1601d52c82efa4e9facb8228f
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 ABCA13 AK9 VWA3B CCDC180 DNAH6	5.23e-05	195	150	6	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 ABCA13 AK9 VWA3B CCDC180 DNAH6	5.23e-05	195	150	6	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	RTTN RRM1 PAICS ORC1 FANCB MYBL2	5.23e-05	195	150	6	56d8734d020b3da08a5aa9e67999706a9e023a99
ToppCell	AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	RASGRF1 MYO6 ATP8B1 SCNN1B HABP2 ADGRF1	5.53e-05	197	150	6	5e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ELAPOR2 CEP290 CCDC141 EGFR ECEL1 SLC4A11	5.53e-05	197	150	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ELAPOR2 USP13 RASGRF1 CCDC141 SEMA4A ARIH1	5.53e-05	197	150	6	bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 PAICS MSN AFAP1 DST TAOK1	5.69e-05	198	150	6	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PAICS ORC1 CKAP2L SLAMF7 SEC61A1 MYBL2	5.69e-05	198	150	6	2d8d4eb21b4fe3cc178b3518b3ea39c2d9650f24
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ELAPOR2 RASGRF1 MYO6 ESRP1 CCDC141 EGFR	5.85e-05	199	150	6	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 PAICS MSN DST TAOK1 SEC61A1	5.85e-05	199	150	6	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	(2)_B_cell-(24)_B_cell_cycling\|(2)_B_cell / shred on Cell_type and subtype	RRM1 CR1L ORC1 EGFR CKAP2L MYBL2	5.85e-05	199	150	6	d5a9a8a71c4de8cbcef947943f60838731bc640b
ToppCell	Caecum-T_cell-Activated_CD4_T\|T_cell / Region, Cell class and subclass	TCEA3 NAIP S1PR1 RESF1 ANKRD18A SEMA4A	5.85e-05	199	150	6	13173cc4dcc8e856680372b0a4ad4f36afa892c1
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYO6 PARP14 S1PR1 DST RESF1 DYNC1H1	6.02e-05	200	150	6	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 MYO6 TGFBR3 PPP2R2B RESF1 SLAMF7	6.02e-05	200	150	6	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4D MYO6 PLEKHH1 ATP1B3 SEC61A1 FBXW11	6.02e-05	200	150	6	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Club\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	TCEA3 ABCA13 SCNN1B ANKRD36 MUC5AC SLC4A11	6.02e-05	200	150	6	292c63693eb7f435335a8cfba07aa35b72139393
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYO6 PARP14 S1PR1 DST RESF1 DYNC1H1	6.02e-05	200	150	6	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Severe-Developping_Plasmablast\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RRM1 PAICS CKAP2L SLAMF7 SEC61A1 MYBL2	6.02e-05	200	150	6	6d0cd00e52568d23597cc2a4059bd967d7d2dab5
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AFAP1 ADGRF1 MUC5AC JRKL SLC4A11 PDE11A	6.02e-05	200	150	6	68b0f987c4fb8078675475f4f1e71302f832ef69
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYO6 PARP14 S1PR1 DST RESF1 DYNC1H1	6.02e-05	200	150	6	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 MYO6 TGFBR3 PPP2R2B RESF1 SLAMF7	6.02e-05	200	150	6	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	erythropoietic-Polychromatic_Erythroblast\|erythropoietic / Lineage and Cell class	TLCD4 RRM1 CR1L SQOR ATP1B3 MYBL2	6.02e-05	200	150	6	27056f28328df2a51d5634a7927b7084241e3ca2
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4D MYO6 PLEKHH1 ATP1B3 SEC61A1 FBXW11	6.02e-05	200	150	6	f0c338877e39226a90c4effe12f6501d33542a73
ToppCell	Severe-Developping_Plasmablast\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RRM1 PAICS CKAP2L SLAMF7 SEC61A1 MYBL2	6.02e-05	200	150	6	80639e0d2ddaae36ac7634a4f03e8809af7316e3
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE\|Thalamus / BrainAtlas - Mouse McCarroll V32	ESRP1 PLEKHH1 TDRD6 ATP1B3 IL17RB	7.60e-05	129	150	5	b3cb0c10659d1216b8f7de3aa1f9aac101cb65dd
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE-O2\|Striatum / BrainAtlas - Mouse McCarroll V32	ESRP1 PLEKHH1 TDRD6 IL17RB	1.20e-04	75	150	4	a34bb5997d056727abce1095f762f94b7818c105
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)\|Striatum / BrainAtlas - Mouse McCarroll V32	ESRP1 PLEKHH1 TDRD6 IL17RB	1.20e-04	75	150	4	dfc7007f3ecf2b340dbbca519db013c72b3cbbf4
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE-O2-Trf\|Striatum / BrainAtlas - Mouse McCarroll V32	ESRP1 PLEKHH1 TDRD6 IL17RB	1.20e-04	75	150	4	9501cfd3c5ec820f363e9a52181de34bac725036
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-\|Striatum / BrainAtlas - Mouse McCarroll V32	ESRP1 PLEKHH1 TDRD6 IL17RB	1.20e-04	75	150	4	0e25dcbb4194c2f96c9591020f5bddd41542c2b5
ToppCell	LPS-antiTNF-Endothelial-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ESRP1 RASGEF1A ORC1 DNAH6 SLC4A11	1.28e-04	144	150	5	75b16adfbe84f69376e6566d531ba7919d5c5192
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 MYLK4 MYO15A ADGRF1 PDE11A	1.32e-04	145	150	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	droplet-Lung-nan-3m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAPOR2 STRA8 ORC1 TMEM131L SLAMF7	1.64e-04	152	150	5	77b319f594d5e4df29034bbf69c7490076f89dd3
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Efhd2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RASSF10 ORC1 PTX3 MYBL2	1.70e-04	82	150	4	93b75f8822ffe8870195cd1fe0a7286478f61e79
ToppCell	Myeloid-F\|World / shred on cell class and cell subclass (v4)	SEMA4D PARP14 RESF1 SEMA4A SLAMF7	1.75e-04	154	150	5	6d53eec4aefe54836bbfd314f28f5e9a24c2d833
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCC4 INAFM2 ZNF618 DST TLR3	1.91e-04	157	150	5	d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCell	Influenza_Severe-CD4+_T_naive\|Influenza_Severe / Disease group and Cell class	TCEA3 CCDC141 ANKRD18A MYO15A DNAH6	1.91e-04	157	150	5	287bdc4e455cd0160261a93d13538e0def49fcd4
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 XIRP2 ADGRF1 MUC5AC SLC4A11	2.03e-04	159	150	5	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCEA3 STRA8 TLR3 SEMA4A SLAMF7	2.03e-04	159	150	5	7bb76324d2026d4bd348126cb169c8411f0d7145
ToppCell	356C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SMG1 COL6A5 S1PR1 DST AGTR1	2.09e-04	160	150	5	0293b244c063a62819690bf22bbc2681f8d15252
ToppCell	356C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SMG1 COL6A5 S1PR1 DST AGTR1	2.09e-04	160	150	5	3eaae86fa08f7651021316f8e5811bf48055591e
ToppCell	Severe-Lymphoid-NK-\|Severe / Condition, Lineage, Cell class and cell subclass	IFT140 NACA2 CUBN TGFBR3 PPP2R2B	2.09e-04	160	150	5	d276c6cb8317d5fb19e7b4fe5238abaf0272d4c6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC4 CR1L SCNN1B ATP1B3 ADGRF1	2.15e-04	161	150	5	176a4a72bb4892932da3c834d1fea5e211847f92
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FCRL2 ERAP2 PIK3CG SLAMF7 RIC1	2.21e-04	162	150	5	8ed9149ff53b285591354057055d072b203a47c8
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ELAPOR2 ABCA13 PPP2R2B MYLK4 PDE11A	2.21e-04	162	150	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FCRL2 ERAP2 PIK3CG SLAMF7 RIC1	2.21e-04	162	150	5	7a05b05a33e1309fb5c0a8171db105ae68491815
ToppCell	Healthy_Control-Lymphoid-B-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	FCRL2 ELAPOR2 QRICH2 MYEF2 PLEKHH1	2.27e-04	163	150	5	d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCell	Healthy_Control-Lymphoid-B\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	FCRL2 ELAPOR2 QRICH2 MYEF2 PLEKHH1	2.27e-04	163	150	5	0f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE\|Striatum / BrainAtlas - Mouse McCarroll V32	ESRP1 PLEKHH1 TDRD6 IL17RB	2.33e-04	89	150	4	ee1dd3571f5914a8274b71f9ca8b36132ae87fe1
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C8orf89 TTLL3 AK9 CCDC180 DNAH6	2.34e-04	164	150	5	d9531848105d606adedde65426177cf851140e31
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	GRIK2 LRRN3 XIRP2 TDRD6 SLAMF7	2.34e-04	164	150	5	362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
Disease	nonsyndromic deafness (implicated_via_orthology)	ALG10B ALG10 PPIP5K2	2.30e-06	6	145	3	DOID:0050563 (implicated_via_orthology)
Disease	Human papillomavirus infectious disease (is_marker_for)	CCNG1 EGFR TLR3	1.36e-05	10	145	3	DOID:11166 (is_marker_for)
Disease	Bardet-Biedl syndrome 14	TMEM67 CEP290	2.40e-05	2	145	2	cv:C2673874
Disease	BARDET-BIEDL SYNDROME 14 (disorder)	TMEM67 CEP290	2.40e-05	2	145	2	C2673874
Disease	BARDET-BIEDL SYNDROME 14	TMEM67 CEP290	2.40e-05	2	145	2	615991
Disease	Bardet-Biedl syndrome 14 (is_implicated_in)	TMEM67 CEP290	2.40e-05	2	145	2	DOID:0110136 (is_implicated_in)
Disease	Long Qt Syndrome 2	ALG10B ALG10	7.17e-05	3	145	2	C3150943
Disease	Hermansky-Pudlak syndrome 1 (implicated_via_orthology)	HPS1 AP3D1	7.17e-05	3	145	2	DOID:0060539 (implicated_via_orthology)
Disease	phosphatidylcholine measurement	ABCA1 RAPSN TLCD4 GRIK2 PLEKHH1 OSBP MALRD1 DYNC1H1	8.52e-05	284	145	8	EFO_0010226
Disease	Muscular Atrophy, Spinal, Type II	NAIP DYNC1H1	1.43e-04	4	145	2	C0393538
Disease	Muscular atrophy, spinal, infantile chronic form	NAIP DYNC1H1	1.43e-04	4	145	2	C2931358
Disease	Juvenile Spinal Muscular Atrophy	NAIP DYNC1H1	1.43e-04	4	145	2	C0152109
Disease	HMN (Hereditary Motor Neuropathy) Proximal Type I	NAIP DYNC1H1	1.43e-04	4	145	2	C0043116
Disease	Menkes disease (implicated_via_orthology)	BTRC FBXW11	2.38e-04	5	145	2	DOID:1838 (implicated_via_orthology)
Disease	neutropenia, response to metamizole, Drug-induced agranulocytosis	TGFBR3 EPHX4	3.55e-04	6	145	2	EFO_0010971, HP_0012235, MONDO_0001475
Disease	proteinuria (implicated_via_orthology)	TMEM67 HPS1 AGTR1	4.28e-04	30	145	3	DOID:576 (implicated_via_orthology)
Disease	Abnormality of the eye	MED13 FBXW11	4.96e-04	7	145	2	C4316870
Disease	cerebrospinal fluid clusterin measurement	ABCA13 DST IPMK	6.78e-04	35	145	3	EFO_0007657
Disease	response to methylphenidate	SQOR PTCD3	8.44e-04	9	145	2	GO_0036271
Disease	Meckel-Gruber syndrome	TMEM67 CEP290	1.05e-03	10	145	2	cv:C0265215
Disease	Hermanski-Pudlak Syndrome	HPS1 AP3D1	1.05e-03	10	145	2	C0079504
Disease	cystic kidney disease (implicated_via_orthology)	TMEM67 CEP290	1.05e-03	10	145	2	DOID:2975 (implicated_via_orthology)
Disease	Hermansky-Pudlak syndrome	HPS1 AP3D1	1.05e-03	10	145	2	cv:C0079504
Disease	primary immunodeficiency disease (is_implicated_in)	IFNAR1 PIK3CG TLR3	1.16e-03	42	145	3	DOID:612 (is_implicated_in)
Disease	Cystic Kidney Diseases	TMEM67 SEC61A1	1.28e-03	11	145	2	C1691228
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	PPP2R2D PPP2R2B	1.53e-03	12	145	2	DOID:1441 (implicated_via_orthology)
Disease	level of Sphingomyelin (d34:2) in blood serum	RAPSN RIC1	1.81e-03	13	145	2	OBA_2045174
Disease	Bardet-Biedl Syndrome	TMEM67 CEP290	1.81e-03	13	145	2	C0752166
Disease	rhinitis (biomarker_via_orthology)	OPA1 MUC5AC	1.81e-03	13	145	2	DOID:4483 (biomarker_via_orthology)
Disease	pulmonary fibrosis (biomarker_via_orthology)	EGFR HABP2 MUC5AC	1.92e-03	50	145	3	DOID:3770 (biomarker_via_orthology)
Disease	Meckel-Gruber syndrome	TMEM67 CEP290	2.41e-03	15	145	2	C0265215
Disease	platelet storage pool deficiency (implicated_via_orthology)	HPS1 AP3D1	2.41e-03	15	145	2	DOID:2223 (implicated_via_orthology)
Disease	head and neck squamous cell carcinoma (is_implicated_in)	TNFRSF10B FANCB	2.41e-03	15	145	2	DOID:5520 (is_implicated_in)
Disease	employment status	ADAM32 SQOR	2.41e-03	15	145	2	EFO_0005241
Disease	HOMA-B	ABCA1 RAPSN TGFBR3	2.53e-03	55	145	3	EFO_0004469
Disease	Polydactyly	TMEM67 IFT140 CEP290 CKAP2L	2.70e-03	117	145	4	C0152427
Disease	phosphatidylcholine 38:6 measurement	RAPSN DEPDC5	2.75e-03	16	145	2	EFO_0010388
Disease	level of Phosphatidylcholine (18:0_20:3) in blood serum	RAPSN TLCD4	2.75e-03	16	145	2	OBA_2045093
Disease	extrahepatic cholestasis (biomarker_via_orthology)	ABCC4 ABCA1	3.11e-03	17	145	2	DOID:13619 (biomarker_via_orthology)
Disease	eicosapentaenoate EPA; 20:5n3 measurement	RAPSN GRIK2	3.11e-03	17	145	2	EFO_0021049
Disease	Meckel syndrome type 1	TMEM67 CEP290	3.48e-03	18	145	2	C3714506
Disease	Adrenocortical carcinoma	RRM1 EGFR	3.48e-03	18	145	2	C0206686
Disease	Bardet-Biedl syndrome	TMEM67 CEP290	3.48e-03	18	145	2	cv:C0752166
Disease	Disorder of eye	TMEM67 CEP290 PRPF6 OPA1 SEMA4A	4.04e-03	212	145	5	C0015397
Disease	renal system measurement	SCAF8 GRIK2	4.30e-03	20	145	2	EFO_0004742
Disease	urinary microalbumin measurement	RASSF10 CUBN	4.30e-03	20	145	2	EFO_0010967
Disease	Familial aplasia of the vermis	TMEM67 CEP290	4.30e-03	20	145	2	cv:C0431399
Disease	Parkinson's disease (is_marker_for)	APAF1 EGFR AGTR1	4.42e-03	67	145	3	DOID:14330 (is_marker_for)
Disease	Infiltrating duct carcinoma of female breast	SMG1 MYLK4	4.74e-03	21	145	2	C3165106
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	ABCA1 RAPSN	4.74e-03	21	145	2	OBA_2045104
Disease	platelet measurement	ABCC4 RAPSN RTTN CKAP2L TMEM131L TAOK1	4.76e-03	315	145	6	EFO_0005036
Disease	gestational age	TGFBR3 MALRD1 CKAP2L VWA3B	4.87e-03	138	145	4	EFO_0005112

Protein segments in the cluster

Peptide	Gene	Start	Entry
KTVLLKKIAFLWASG	NAIP	476	Q13075
FIATCSVDKKVKIWN	APAF1	671	O14727
FLLSTNDKTVKLWKV	PPP2R2B	106	Q00005
WTSKKKLFQVEIQPE	ANKRD18A	656	Q8IVF6
DKLKSTLKQFVRDWS	CARNMT1	156	Q8N4J0
IEALFWKQIKKSQTS	ADGRF1	606	Q5T601
ILTSYTLIWKALKKA	AGTR1	211	P30556
FGQWTKLLCVIKDTK	AFAP1	166	Q8N556
EWTKICEKSTKVITF	GTPBP1	236	O00178
KIWDKNTLECKRILT	BTRC	326	Q9Y297
IIAKSLKNKIWVNEF	ABCA1	1516	O95477
FESSWKKAVLETQKI	C8orf89	26	P0DMQ9
ISLVKTVQKFWHKIL	ABCA13	1911	Q86UQ4
FLLSTNDKTIKLWKI	PPP2R2D	116	Q66LE6
VTTAIVLARKQLKKW	ADAM32	696	Q8TC27
IAQKLTEAWKTELQK	ALG10B	201	Q5I7T1
KIKTFLSLVWKHGIL	ALG10B	311	Q5I7T1
WKVIFKKKVSLLNIA	ANKRD36	621	A6QL64
WKALKKEALLQSFSE	CCDC180	351	Q9P1Z9
FAKLKSKLVLWDINK	HSD17B11	56	Q8NBQ5
KILSLSAFWIKIKDD	FAM200A	491	Q8TCP9
KEAVTQTKAKAWALV	ARMCX4	161	Q5H9R4
ETISKLAKADIKIWV	ATP8B1	716	O43520
SSTNNWVLIKIIKLF	AP3D1	231	O14617
ILLFWKVVDLANKKV	ESRP1	31	Q6NXG1
KKISVWICQEEKLVS	RASSF10	6	A6NK89
QTEKALQVWTKVLEK	RAPSN	21	Q13702
QEQLKTVKTLAKEVW	QRICH2	1081	Q9H0J4
LLTKKWKLFGNITQE	RIC1	521	Q4ADV7
AFILLLVVAFSKKWL	ODF4	91	Q2M2E3
SWIEVQFLKKAVDVL	ARIH1	451	Q9Y4X5
VLEKVCWKVKATTAF	CCNG1	141	P51959
EWTSLLVTIKKLFIQ	DEPDC5	266	O75140
KKKTWDKVAVLQALA	PTCD3	61	Q96EY7
ELKEFVKISKWNDVS	MDN1	3941	Q9NU22
VKTILSKKINWIVQY	EURL	86	Q9NYK6
STAINWLTKKFLLKK	MYO15A	131	Q9UKN7
VNKLIWTFLKEETRK	EPHX4	346	Q8IUS5
AKELQKWVSNISKTL	DST	1446	Q03001
AFQVLVKSLKSWIKE	DST	4376	Q03001
WLATQKKAADKVVFL	IL17RB	381	Q9NRM6
KLATKFVDKTEWIKS	ECPAS	686	Q5VYK3
KVKAALLTSWKIGVY	IFNAR1	201	P17181
QVKKSWAKQSVALDV	PDE11A	566	Q9HCR9
SIKIWDKTSLECLKV	FBXW11	261	Q9UKB1
EFISKLLIKEKSWRI	MYLK4	336	Q86YV6
FKKSAETLWNIQKDL	LDHC	316	P07864
STWLKLNKKVTAQDV	MSN	56	P26038
NDLKSFWKKLTLLDA	JRKL	351	Q9Y4A0
VLLWDKKTSIFINLS	MUC5AC	1011	P98088
RWVTALELAKAKAVK	OSBP	171	P22059
VKKIRQEVDKSTWLL	ECEL1	551	O95672
KKLATCETVDFWLKV	ELAPOR2	916	A8MWY0
VAASIQKIEKILQWF	IPMK	226	Q8NFU5
LNNEWTVEKLKSKLV	LRRC8B	401	Q6P9F7
FQVAAKWEKLSLVLI	FANCB	316	Q8NB91
WEKSFSNLITNLRKK	ABCC4	291	O15439
TTVDIKLKQWTDKQL	OPA1	651	O60313
KTEVLKAVDIVKQVW	PARP14	721	Q460N5
TNLKNEKTLFVKLSW	ORC1	146	Q13415
FILKKSSSLWQVAKL	MALRD1	706	Q5VYJ5
LQVLIKKDNVTSKLW	MALRD1	1191	Q5VYJ5
ASLKLTETQVKIWFQ	NKX3-2	241	P78367
SNKLWLKFKSDQIDT	CUBN	1136	O60494
TQVTKFLNWIKATIK	HABP2	541	Q14520
KTVKEITGFLLIQAW	EGFR	396	P00533
KKVEDSWKTTEFVIL	DNAH6	1026	Q9C0G6
NKLFWKEIQDVTIIS	DNAH6	2196	Q9C0G6
AEKQWQLFLKKSFIT	CCDC141	606	Q6ZP82
VNAKVEEWKLILSSK	CEP290	306	O15078
FVENTWKIKFINLKI	C3orf38	261	Q5JPI3
SWNISVVKFLLEKLK	C14orf93	331	Q9H972
STKFLKKLQNEIWSQ	COL6A5	406	A8TX70
IICLKNSVWTSAKDK	CR1L	76	Q2VPA4
KARTAQLAKIKWVIS	GET1	91	O00258
FLSLLLVAAVVWKIK	ATRNL1	1241	Q5VV63
FQTVLETITKNIKWL	ERAP2	931	Q6P179
IKSKIDNAKSFEWLS	DYNC1H1	1826	Q14204
ISWKKTIVTRFLKLV	HEATR1	1631	Q9H583
WDKTSNIVKIKVQEL	FCRL2	91	Q96LA5
LDLVQFFKWKTVTVV	GRIK2	161	Q13002
KWILENKAGISFIIK	GTF2I	171	P78347
AFVKTKVWSLIQLAR	HPS1	576	Q92902
LKNLNKKLFTVVAWD	BPHL	81	Q86WA6
RVEWLSTTKDKNIVK	PIWIL3	191	Q7Z3Z3
SYKIGSKVIKIAWAL	SCAF8	536	Q9UPN6
LENIFVLLTIWKTKK	S1PR1	61	P21453
DFVWITIIKLVALAK	SCNN1B	546	P51168
AFKSIKLIKSEAVWE	IFT140	791	Q96RY7
IWVKATDVLNKTILF	PTX3	211	P26022
AAKTNKKWVRLATVF	INAFM2	26	P0DMQ5
WLIFFKAQKSVSVLL	TMEM67	586	Q5HYA8
LTLNTVFVLAVKLKW	RNF139	186	Q8WU17
IKEIISICSKIWKSA	RTTN	591	Q86VV8
LGNKKLKQIFLSVFW	TAS2R36	281	P0DTE0
FKEKIGSFIILWKQL	AK9	831	Q5TCS8
FVLDAVKGTVKIFWK	SLC4A11	486	Q8NBS3
SVKTVEKTWKALQDF	SQOR	171	Q9Y6N5
VVVWFQETILDKSLK	TDRD6	1111	O60522
WNIFSLKLAVKDIAI	TMEM131L	451	A2VDJ0
WIFASKFIIVTGQIK	TMEM191A	36	Q9H0A3
WKKLKEVFSIAGTVK	MYEF2	246	Q9P2K5
KILKSSVKWTAFVKT	LRRN3	546	Q9H3W5
AVAKLFWSQRKITKA	PRPF6	846	O94906
IKSTKEDWLKFVATK	RESF1	1671	Q9HCM1
ELVKKYGTKQWTLIA	MYBL2	96	P10244
VAKSILTLAKWIQAE	SMG1	1521	Q96Q15
EKLLQKKWTTFLKAQ	SEMA4A	276	Q9H3S1
KKWTTFLKAQLLCTQ	SEMA4A	281	Q9H3S1
TKFWIKQKPISIDSD	MAPKAP1	421	Q9BPZ7
STEKWQDIIKEVKFL	TAOK1	66	Q7L7X3
IWTKNKELELSVPKF	SETD1B	76	Q9UPS6
TLQKKWTSFLKARLI	SEMA4D	266	Q92854
TASKKLSEKLVAEWF	MED13	1421	Q9UHV7
KGKLFTWNILKTIAL	SLC35F2	31	Q8IXU6
KSVVWQKIKATVFDD	STXBP3	11	O00186
KTWLKVSKQTKALID	RASGRF1	1146	Q13972
DLIASKWQVLNKAKS	STRA8	81	Q7Z7C7
IAQKLTEAWKTELQK	ALG10	201	Q5BKT4
KKSLNQSLAEWKLFI	ATP1B3	6	P54709
KVIKEMNISFWKSIE	CKAP2L	491	Q8IYA6
TLWDQVLTVFKDIQK	C12orf54	41	Q6X4T0
NVWLEFSIKIKDLPK	PIK3CG	411	P48736
SKAKWLFETQPLEKI	XIRP2	631	A4UGR9
ILNTWISLKQADKKI	PAICS	406	P22234
DIKKVWSDIISVVIK	TTLL11	471	Q8NHH1
KNKISKIESDAFSWL	TLR3	416	O15455
VTQKHTKLAKLAFWL	ZNF618	896	Q5T7W0
KSFSAKIVQLLKEWT	RASGEF1A	111	Q8N9B8
VSLWSLINSNKEKFK	MTM1	496	Q13496
PIWVSVLLKKTEKAF	RP1L1	1516	Q8IWN7
WLEKKVNQTVAALKT	RNASEH2B	166	Q5TBB1
AFTETQKKRLLSWKQ	SAMD4B	511	Q5PRF9
LKTFWKGFTILDAIK	TIGD1	371	Q96MW7
LKQLYKTVWEISQKT	RRM1	676	P23921
LPEKWESVKLLFVKT	RSL1D1	241	O76021
IQFKEKVLWTAITLF	SEC61A1	26	P61619
SVQLFSKKFKLWLLN	RFX8	251	Q6ZV50
LSFKKKIEWNSRVVS	TLCD4	41	Q96MV1
DKEVVSLAKVLIKNW	TCEA3	61	O75764
KTAQVLSKWDPVVLK	UTP14A	136	Q9BVJ6
IVAVFVCKSLLWKKV	TNFRSF10B	226	O14763
LKSKVKQVDSIVWTF	SLAMF7	41	Q9NQ25
ARNVLKLVVKSEWKS	TTLL3	151	Q9Y4R7
EKAAKIKEWVTLKLA	PLEKHH1	126	Q9ULM0
ENWLKTYGLVAKKLT	VWA3B	846	Q502W6
KLIAWKVCLAFKQTV	PPIP5K2	291	O43314
NVTKITLESFLAWKK	ZC3H15	246	Q8WU90
ILSKVEKFLTWVNKP	TGS1	511	Q96RS0
SLKDALFKWESKTVL	USP8	276	P40818
LVVQIKKFTFGLDWV	USP13	581	Q92995
LILKCKKSVNWVIKS	TGFBR3	271	Q03167
WVIKSFDVKGSLKII	TGFBR3	281	Q03167
KSDWKVVRKALTVID	MYO1C	281	O00159
IWKSKNILFVITKLD	NACA2	96	Q9H009
VQWCSLSVIKLKNKI	MYO6	796	Q9UM54
DFALLWKIEKNKISI	N4BP2	1021	Q86UW6
LFLWIVKKINAAIFT	MYO7B	406	Q6PIF6