Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	insulin-like growth factor I binding	ITGAV IGFBP5 LRP2	6.09e-05	13	122	3	GO:0031994
GeneOntologyMolecularFunction	insulin-like growth factor binding	ITGAV IGFBP5 LRP2	2.01e-04	19	122	3	GO:0005520
GeneOntologyMolecularFunction	mediator complex binding	SMC1A SMC3	2.20e-04	4	122	2	GO:0036033
GeneOntologyBiologicalProcess	regulation of synaptic vesicle fusion to presynaptic active zone membrane	CACNA1B GRIK5 RIMS1 RIMS2	5.42e-06	20	123	4	GO:0031630
GeneOntologyBiologicalProcess	regulation of synaptic vesicle membrane organization	CACNA1B GRIK5 RIMS1 RIMS2	5.42e-06	20	123	4	GO:1901632
GeneOntologyBiologicalProcess	regulation of calcium-dependent activation of synaptic vesicle fusion	CACNA1B RIMS1 RIMS2	7.12e-06	7	123	3	GO:0150037
GeneOntologyBiologicalProcess	synaptic vesicle fusion to presynaptic active zone membrane	CACNA1B GRIK5 RIMS1 RIMS2	3.34e-05	31	123	4	GO:0031629
GeneOntologyBiologicalProcess	vesicle fusion to plasma membrane	CACNA1B GRIK5 RIMS1 RIMS2	3.81e-05	32	123	4	GO:0099500
GeneOntologyBiologicalProcess	regulation of vesicle fusion	CACNA1B GRIK5 RIMS1 RIMS2	5.46e-05	35	123	4	GO:0031338
GeneOntologyBiologicalProcess	positive regulation of synaptic vesicle fusion to presynaptic active zone membrane	CACNA1B RIMS1 RIMS2	5.67e-05	13	123	3	GO:0031632
GeneOntologyBiologicalProcess	positive regulation of synaptic vesicle membrane organization	CACNA1B RIMS1 RIMS2	5.67e-05	13	123	3	GO:1901634
GeneOntologyBiologicalProcess	calcium-dependent activation of synaptic vesicle fusion	CACNA1B RIMS1 RIMS2	5.67e-05	13	123	3	GO:0099502
GeneOntologyBiologicalProcess	synaptic vesicle membrane organization	CACNA1B GRIK5 RIMS1 RIMS2	6.12e-05	36	123	4	GO:0048499
GeneOntologyBiologicalProcess	positive regulation of vascular associated smooth muscle cell migration	DOCK5 IGFBP5 DOCK7 LRP1	6.12e-05	36	123	4	GO:1904754
GeneOntologyBiologicalProcess	synaptic vesicle exocytosis	CACNA1B GRIK5 BRAF RIMS1 CADPS2 RIMS2	1.05e-04	125	123	6	GO:0016079
GeneOntologyBiologicalProcess	signal release from synapse	CACNA1B HTR6 GRIK5 BRAF RIMS1 CADPS2 RIMS2	1.71e-04	195	123	7	GO:0099643
GeneOntologyBiologicalProcess	neurotransmitter secretion	CACNA1B HTR6 GRIK5 BRAF RIMS1 CADPS2 RIMS2	1.71e-04	195	123	7	GO:0007269
GeneOntologyBiologicalProcess	establishment of meiotic sister chromatid cohesion	SMC1A SMC3	2.10e-04	4	123	2	GO:0034089
GeneOntologyBiologicalProcess	positive regulation of vesicle fusion	CACNA1B RIMS1 RIMS2	2.19e-04	20	123	3	GO:0031340
GeneOntologyBiologicalProcess	positive regulation of lysosomal protein catabolic process	LRP1 LRP2	3.49e-04	5	123	2	GO:1905167
GeneOntologyBiologicalProcess	chemoattraction of axon	LRP1 LRP2	3.49e-04	5	123	2	GO:0061642
Domain	SMC	SMC1A SMC3	4.04e-04	5	120	2	IPR024704
Domain	SMC_hinge	SMC1A SMC3	6.04e-04	6	120	2	SM00968
Domain	SMC_hinge	SMC1A SMC3	6.04e-04	6	120	2	PF06470
Domain	SMC_hinge	SMC1A SMC3	6.04e-04	6	120	2	IPR010935
Domain	Transketolase-like_Pyr-bd	TKT DHTKD1	1.12e-03	8	120	2	IPR005475
Domain	Transket_pyr	TKT DHTKD1	1.12e-03	8	120	2	SM00861
Domain	Transket_pyr	TKT DHTKD1	1.12e-03	8	120	2	PF02779
Domain	RecF/RecN/SMC_N	SMC1A SMC3	1.12e-03	8	120	2	IPR003395
Domain	SMC_N	SMC1A SMC3	1.12e-03	8	120	2	PF02463
Domain	C2	CAPN6 PLCL2 RIMS1 CADPS2 RIMS2	1.57e-03	131	120	5	PF00168
Domain	C2	CAPN6 PLCL2 RIMS1 CADPS2 RIMS2	1.92e-03	137	120	5	SM00239
Domain	TYR_PHOSPHATASE_PTP	PTPN21 PTP4A1 PTPRD	2.00e-03	39	120	3	PS50055
Domain	DHR-1_domain	DOCK5 DOCK7	2.17e-03	11	120	2	IPR027007
Domain	DHR_2	DOCK5 DOCK7	2.17e-03	11	120	2	PS51651
Domain	DHR_1	DOCK5 DOCK7	2.17e-03	11	120	2	PS51650
Domain	FYVE_2	RIMS1 RIMS2	2.17e-03	11	120	2	PF02318
Domain	DHR-2	DOCK5 DOCK7	2.17e-03	11	120	2	PF06920
Domain	DOCK	DOCK5 DOCK7	2.17e-03	11	120	2	IPR026791
Domain	DOCK_C	DOCK5 DOCK7	2.17e-03	11	120	2	IPR010703
Domain	DOCK-C2	DOCK5 DOCK7	2.17e-03	11	120	2	PF14429
Domain	DHR-2	DOCK5 DOCK7	2.17e-03	11	120	2	IPR027357
Domain	C2	CAPN6 PLCL2 RIMS1 CADPS2 RIMS2	2.24e-03	142	120	5	PS50004
Domain	PTPase_domain	PTPN21 PTP4A1 PTPRD	2.31e-03	41	120	3	IPR000242
Domain	Y_phosphatase	PTPN21 PTP4A1 PTPRD	2.31e-03	41	120	3	PF00102
Domain	RABBD	RIMS1 RIMS2	2.59e-03	12	120	2	PS50916
Domain	Rab_BD	RIMS1 RIMS2	2.59e-03	12	120	2	IPR010911
Domain	PDZ	SHROOM4 RIMS1 FRMPD3 RIMS2 PREX1	2.68e-03	148	120	5	SM00228
Domain	-	SHROOM4 RIMS1 FRMPD3 RIMS2 PREX1	2.84e-03	150	120	5	2.30.42.10
Domain	PDZ	SHROOM4 RIMS1 FRMPD3 RIMS2 PREX1	2.92e-03	151	120	5	PS50106
Domain	PDZ	SHROOM4 RIMS1 FRMPD3 RIMS2 PREX1	3.01e-03	152	120	5	IPR001478
Domain	Med26	ELOA2 IWS1	3.05e-03	13	120	2	PF08711
Domain	THDP-binding	TKT DHTKD1	3.05e-03	13	120	2	IPR029061
Domain	-	TKT DHTKD1	3.05e-03	13	120	2	3.40.50.970
Domain	-	ELOA2 IWS1	3.05e-03	13	120	2	1.20.930.10
Domain	TFIIS_N	ELOA2 IWS1	3.05e-03	13	120	2	PS51319
Domain	Dynein_heavy_chain_D4_dom	DNAH14 DYNC1H1	3.54e-03	14	120	2	IPR024317
Domain	Dynein_HC_stalk	DNAH14 DYNC1H1	3.54e-03	14	120	2	IPR024743
Domain	TFIIS_N	ELOA2 IWS1	3.54e-03	14	120	2	IPR017923
Domain	MT	DNAH14 DYNC1H1	3.54e-03	14	120	2	PF12777
Domain	AAA_8	DNAH14 DYNC1H1	3.54e-03	14	120	2	PF12780
Domain	Ldl_recept_b	LRP1 LRP2	3.54e-03	14	120	2	PF00058
Domain	LDLRB	LRP1 LRP2	3.54e-03	14	120	2	PS51120
Domain	DHC_fam	DNAH14 DYNC1H1	4.07e-03	15	120	2	IPR026983
Domain	Dynein_heavy	DNAH14 DYNC1H1	4.07e-03	15	120	2	PF03028
Domain	LY	LRP1 LRP2	4.07e-03	15	120	2	SM00135
Domain	Dynein_heavy_dom	DNAH14 DYNC1H1	4.07e-03	15	120	2	IPR004273
Domain	LDLR_classB_rpt	LRP1 LRP2	4.07e-03	15	120	2	IPR000033
Domain	C2_dom	CAPN6 PLCL2 RIMS1 CADPS2 RIMS2	4.16e-03	164	120	5	IPR000008
Domain	PINT	PSMD3 EIF3A	4.63e-03	16	120	2	SM00088
Domain	PCI_dom	PSMD3 EIF3A	5.23e-03	17	120	2	IPR000717
Domain	PCI	PSMD3 EIF3A	5.23e-03	17	120	2	PF01399
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	NEPRO NPEPPS SMC1A AMBRA1 PSMD3 IWS1 UBR5 SMC3 TBK1 SHPRH DOCK7 LRP1 EIF3A NUDCD1 HECTD1 TBP EIF4E2	1.01e-07	1005	123	17	19615732
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	HSPA4L NPEPPS SMC1A ELOVL1 PSMD3 LRRK1 MYCBPAP PTP4A1 PPP1R7 BRAF UBR5 SMC3 TKT EIF3A RIMS1 CPVL PREX1 DYNC1H1 EIF4E2	1.33e-07	1284	123	19	17353931
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	MPO HSPA4L NPEPPS SMC1A AMBRA1 PSMD3 PTPN21 PTP4A1 PTPRD UBR5 SMC3 TKT LRP1 EIF3A HECTD1 CPVL	3.65e-07	974	123	16	28675297
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	AMER1 SMC1A BRAF UBR5 SMC3 TBK1 DOCK7 PKP2 HECTD1 CPVL EIF4E2	5.80e-07	446	123	11	24255178
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR7D4 OR7A5 OR1J1 OR1I1 OR7D2 OR1A1 OR1P1 OR7A10	1.20e-06	219	123	8	12213199
Pubmed	Rebuilding essential active zone functions within a synapse.	CACNA1B RIMS1 RIMS2	1.50e-06	7	123	3	35176221
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	AMER1 HJURP AMBRA1 UBR5 DOCK7 HECTD1 DYNC1H1 EIF4E2	1.85e-06	232	123	8	25515538
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	HSPA4L NPEPPS SMC1A PSMD3 PNPT1 SMC3 TKT DYNC1H1	2.17e-06	237	123	8	29564676
Pubmed	Network organization of the human autophagy system.	NSUN4 NPEPPS SMC1A AMBRA1 SMC3 TKT TBK1 EIF3A CPVL SEC23B	3.75e-06	437	123	10	20562859
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	ADAP1 HSPA4L NPEPPS PSMD3 TKT EIF3A HECTD1 DYNC1H1 SEC23B	3.99e-06	344	123	9	30333137
Pubmed	CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA.	ZIC1 ZIC3 ZIC5	5.09e-06	10	123	3	18298960
Pubmed	Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives.	ZIC1 ZIC3 ZIC5	5.09e-06	10	123	3	15136147
Pubmed	Spatiotemporal expression of Zic genes during vertebrate inner ear development.	ZIC1 ZIC3 ZIC5	5.09e-06	10	123	3	23606270
Pubmed	Identification of ligands for olfactory receptors by functional expression of a receptor library.	OR1A1 OR1P1 OR7A10	9.28e-06	12	123	3	9875846
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	AMPD1 MYOT NRAP SMC1A PHAX PPP1R7 IGFBP5 TKT TBK1 EIF3A	1.15e-05	497	123	10	23414517
Pubmed	Mutations in cohesin complex members SMC3 and SMC1A cause a mild variant of cornelia de Lange syndrome with predominant mental retardation.	SMC1A SMC3	1.24e-05	2	123	2	17273969
Pubmed	RIM2α is a molecular scaffold for Zona pellucida-induced acrosome reaction.	RIMS1 RIMS2	1.24e-05	2	123	2	25240052
Pubmed	Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.	LRP1 CTSD	1.24e-05	2	123	2	20826454
Pubmed	A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion.	SMC1A SMC3	1.24e-05	2	123	2	21139566
Pubmed	Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA.	SMC1A SMC3	1.24e-05	2	123	2	18996922
Pubmed	Analysis of RIM Expression and Function at Mouse Photoreceptor Ribbon Synapses.	RIMS1 RIMS2	1.24e-05	2	123	2	28701482
Pubmed	RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes.	RIMS1 RIMS2	1.24e-05	2	123	2	29606581
Pubmed	RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors.	RIMS1 RIMS2	1.24e-05	2	123	2	26400943
Pubmed	Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.	LRP1 CTSD	1.24e-05	2	123	2	22081071
Pubmed	Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.	LRP1 LRP2	1.24e-05	2	123	2	34445520
Pubmed	A presynaptic phosphosignaling hub for lasting homeostatic plasticity.	RIMS1 RIMS2	1.24e-05	2	123	2	35443170
Pubmed	NLRP2 negatively regulates antiviral immunity by interacting with TBK1.	NLRP2 TBK1	1.24e-05	2	123	2	30183071
Pubmed	Imbalance of SMC1 and SMC3 cohesins causes specific and distinct effects.	SMC1A SMC3	1.24e-05	2	123	2	23776448
Pubmed	RIM genes differentially contribute to organizing presynaptic release sites.	RIMS1 RIMS2	1.24e-05	2	123	2	22753485
Pubmed	Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity.	SMC1A SMC3	1.24e-05	2	123	2	27307603
Pubmed	The presynaptic active zone protein RIM1α controls epileptogenesis following status epilepticus.	RIMS1 RIMS2	1.24e-05	2	123	2	22956829
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	POP7 NEPRO SMC1A PSMD3 UBR5 SMC3 POP1 DOCK7 DYNC1H1	1.31e-05	399	123	9	37536630
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MPO SMC1A ETFB PSMD3 DOCK5 PNPT1 NCOR2 UBR5 SHPRH RIMS2 CTSD DYNC1H1	1.58e-05	754	123	12	35906200
Pubmed	Essential role of MESP1-RING1A complex in cardiac differentiation.	SMC1A ZIC3 SMC3	1.90e-05	15	123	3	36413948
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	SMC1A AMBRA1 PNPT1 UBR5 TKT DOCK7 EIF3A HECTD1 CPVL DYNC1H1	2.13e-05	534	123	10	35032548
Pubmed	Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.	OR1I1 OR7D2 OR1A1 OR7A10	2.17e-05	46	123	4	32126975
Pubmed	Chromosomal location-dependent nonstochastic onset of odor receptor expression.	OR7D4 OR7A5 OR7A10	2.83e-05	17	123	3	20668191
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	AMER1 HSPA4L NPEPPS SMC1A PSMD3 PNPT1 NCOR2 BRAF TULP4 SMC3 TBK1 POP1 PKP2 HECTD1 DYNC1H1	3.59e-05	1247	123	15	27684187
Pubmed	Transcriptional expression of ZICs as an independent indicator of survival in gliomas.	ZIC1 ZIC5	3.71e-05	3	123	2	34475426
Pubmed	Mutations and variants in the cohesion factor genes NIPBL, SMC1A, and SMC3 in a cohort of 30 unrelated patients with Cornelia de Lange syndrome.	SMC1A SMC3	3.71e-05	3	123	2	20358602
Pubmed	RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zone.	RIMS1 RIMS2	3.71e-05	3	123	2	21262468
Pubmed	Clinical and genetic study of 20 patients from China with Cornelia de Lange syndrome.	SMC1A SMC3	3.71e-05	3	123	2	29452578
Pubmed	Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones.	RIMS1 RIMS2	3.71e-05	3	123	2	26034270
Pubmed	The ZIC gene family in development and disease.	ZIC1 ZIC5	3.71e-05	3	123	2	15733262
Pubmed	C-terminal splice variants of P/Q-type Ca2+ channel CaV2.1 α1 subunits are differentially regulated by Rab3-interacting molecule proteins.	RIMS1 RIMS2	3.71e-05	3	123	2	28377503
Pubmed	RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction.	RIMS1 RIMS2	3.71e-05	3	123	2	21241895
Pubmed	The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells.	ZIC1 ZIC3	3.71e-05	3	123	2	22024047
Pubmed	Genetic variants in ZIC1, ZIC2, and ZIC3 are not major risk factors for neural tube defects in humans.	ZIC1 ZIC3	3.71e-05	3	123	2	14679585
Pubmed	Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation.	ZIC1 ZIC3	3.71e-05	3	123	2	15261827
Pubmed	The mouse zic gene family. Homologues of the Drosophila pair-rule gene odd-paired.	ZIC1 ZIC3	3.71e-05	3	123	2	8557628
Pubmed	RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse.	RIMS1 RIMS2	3.71e-05	3	123	2	25343783
Pubmed	Characterization of the components of the putative mammalian sister chromatid cohesion complex.	SMC1A SMC3	3.71e-05	3	123	2	10375619
Pubmed	Proteomic profile identifies dysregulated pathways in Cornelia de Lange syndrome cells with distinct mutations in SMC1A and SMC3 genes.	SMC1A SMC3	3.71e-05	3	123	2	23106691
Pubmed	Novel meiosis-specific isoform of mammalian SMC1.	SMC1A SMC3	3.71e-05	3	123	2	11564881
Pubmed	Loss of Ambra1 promotes melanoma growth and invasion.	AMBRA1 BRAF	3.71e-05	3	123	2	33953176
Pubmed	RIM is essential for stimulated but not spontaneous somatodendritic dopamine release in the midbrain.	RIMS1 RIMS2	3.71e-05	3	123	2	31486769
Pubmed	Congenital heart disease in Cornelia de Lange syndrome: phenotype and genotype analysis.	SMC1A SMC3	3.71e-05	3	123	2	22965847
Pubmed	Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis.	RIMS1 RIMS2	3.71e-05	3	123	2	25730884
Pubmed	Alternative splicing in the first alpha-helical region of the Rab-binding domain of Rim regulates Rab3A binding activity: is Rim a Rab3 effector protein during evolution?	RIMS1 RIMS2	3.71e-05	3	123	2	15330860
Pubmed	Sensory-related neural activity regulates the structure of vascular networks in the cerebral cortex.	RIMS1 RIMS2	3.71e-05	3	123	2	25155955
Pubmed	Expression of ZIC family genes in meningiomas and other brain tumors.	ZIC1 ZIC5	3.71e-05	3	123	2	20199689
Pubmed	Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage.	SMC1A SMC3	3.71e-05	3	123	2	11877376
Pubmed	Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I.	SMC1A SMC3	3.71e-05	3	123	2	11483963
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	NPEPPS SMC1A PSMD3 SMC3 TKT PKP2 EIF3A CTSD DYNC1H1	5.27e-05	477	123	9	31300519
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	NSUN4 AMER1 PPP1R7 NCOR2 UBR5 TBK1 NUDCD1 DNMBP SEC23B EIF4E2	6.00e-05	604	123	10	38803224
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	GRIK5 FMNL2 DNAH14 DOCK5 PPP1R7 TBK1 POP1 LRP2 EIF3A OR7A10 DYNC1H1	6.38e-05	736	123	11	29676528
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMC1A FMNL2 SHROOM4 TULP4 POP1 EIF3A DHTKD1 HECTD1 PREX1	6.78e-05	493	123	9	15368895
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	NPEPPS SMC1A PSMD3 ITGAV SMC3 TKT LRP1 EIF3A CTSD CPVL	6.78e-05	613	123	10	22268729
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	HSPA4L NPEPPS SMC1A PSMD3 LRRK1 SMC3 TKT EIF3A SEC23B	6.89e-05	494	123	9	26831064
Pubmed	The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.	OR7A5 OR1A1 OR7A10	7.26e-05	23	123	3	10706615
Pubmed	Protein composition of axonal dopamine release sites in the striatum.	RIMS1 RIMS2	7.41e-05	4	123	2	36579890
Pubmed	Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics.	SMC1A SMC3	7.41e-05	4	123	2	9789013
Pubmed	Divergent properties and independent regulation of striatal dopamine and GABA co-transmission.	RIMS1 RIMS2	7.41e-05	4	123	2	35584679
Pubmed	Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.	LRP1 LRP2	7.41e-05	4	123	2	12413896
Pubmed	RIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13.	RIMS1 RIMS2	7.41e-05	4	123	2	21262469
Pubmed	Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis.	BRAF LRP1	7.41e-05	4	123	2	37335131
Pubmed	The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells.	SMC1A SMC3	7.41e-05	4	123	2	19629043
Pubmed	Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins.	ZIC1 ZIC3	7.41e-05	4	123	2	11053430
Pubmed	Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.	LRP1 LRP2	7.41e-05	4	123	2	7775583
Pubmed	An Evolutionarily Conserved Mesodermal Enhancer in Vertebrate Zic3.	ZIC1 ZIC3	7.41e-05	4	123	2	30297839
Pubmed	Epithelial cells as phagocytes: apoptotic epithelial cells are engulfed by mammary alveolar epithelial cells and repress inflammatory mediator release.	ITGAV LRP1	7.41e-05	4	123	2	15647754
Pubmed	Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins.	RIMS1 RIMS2	7.41e-05	4	123	2	12620390
Pubmed	Puromycin-sensitive aminopeptidase gene (Psa) maps to mouse chromosome 11.	NPEPPS PSMD3	7.41e-05	4	123	2	10087210
Pubmed	Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system.	ZIC1 ZIC3	7.41e-05	4	123	2	15895369
Pubmed	SUMOylation Potentiates ZIC Protein Activity to Influence Murine Neural Crest Cell Specification.	ZIC3 ZIC5	7.41e-05	4	123	2	34638777
Pubmed	Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression.	ITGAV LRP1	7.41e-05	4	123	2	20558745
Pubmed	A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells.	ZIC1 ZIC3	7.41e-05	4	123	2	7931345
Pubmed	Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.	LRP1 LRP2	7.41e-05	4	123	2	11421580
Pubmed	Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels.	RIMS1 RIMS2	7.41e-05	4	123	2	20452978
Pubmed	Cohesin subunit SMC1 associates with mitotic microtubules at the spindle pole.	SMC1A SMC3	7.41e-05	4	123	2	18832153
Pubmed	Insulin-like growth factor binding protein-5 (IGFBP-5) interacts with thrombospondin-1 to induce negative regulatory effects on IGF-I actions.	ITGAV IGFBP5	7.41e-05	4	123	2	15700281
Pubmed	Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking.	RIMS1 RIMS2	7.41e-05	4	123	2	27537483
Pubmed	A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules.	SMC1A SMC3	7.41e-05	4	123	2	31807710
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	AMER1 HSPA4L PSMD3 PHAX KIAA1143 UBR5 SMC3 TKT POP1 EIF3A HECTD1 CPVL SEC23B TBP EIF4E2	7.73e-05	1335	123	15	29229926
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	AMER1 MAPKAPK2 ETFB SLU7 PHAX ADD3 IWS1 UBR5 TBK1 CEP41 DOCK7 SEC23B EIF4E2	8.22e-05	1038	123	13	26673895
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	PSMD3 ZIC3 NCOR2 UBR5 SMC3 ZIC5 TKT VRTN	8.68e-05	396	123	8	26687479
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MPO NPEPPS SMC1A SLU7 AMBRA1 PSMD3 NCOR2 UBR5 SMC3 TKT POP1 PKP2 EIF3A CTSD DYNC1H1	8.97e-05	1353	123	15	29467282
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	CACNA1B PSMD3 DOCK7 LRP2 RIMS1 EIF4E2	1.01e-04	208	123	6	33230847
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	POP7 NPEPPS ETFB PHAX ITGAV FMNL2 ADD3 PNPT1 BRAF TKT TBK1 POP1 DOCK7 PKP2 DYNC1H1	1.04e-04	1371	123	15	36244648
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	SMC1A PSMD3 PHAX IWS1 PNPT1 YJU2 SMC3 TYW5 POP1 DOCK7	1.14e-04	653	123	10	33742100
GeneFamily	Olfactory receptors, family 1	OR1J1 OR1I1 OR1A1 OR1P1	3.33e-05	40	83	4	147
GeneFamily	Regulating synaptic membrane exocytosis family\|PDZ domain containing	RIMS1 RIMS2	1.24e-04	4	83	2	833
GeneFamily	Structural maintenance of chromosomes proteins\|Cohesin complex	SMC1A SMC3	4.31e-04	7	83	2	761
GeneFamily	Cohesin complex	SMC1A SMC3	5.73e-04	8	83	2	1060
GeneFamily	PDZ domain containing	SHROOM4 RIMS1 FRMPD3 RIMS2 PREX1	6.74e-04	152	83	5	1220
GeneFamily	Low density lipoprotein receptors	LRP1 LRP2	1.57e-03	13	83	2	634
GeneFamily	Olfactory receptors, family 7	OR7D4 OR7A5 OR7D2 OR7A10	1.82e-03	113	83	4	154
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF10L DNMBP PREX1	3.47e-03	66	83	3	722
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	APCDD1 HSPA4L SMC1A ZIC1 ZIC3 IWS1 UBR5 SMC3 ZIC5 TYW5 LRP2 PKP2 EIF3A RIMS2	4.66e-07	498	114	14	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000	MPO NEPRO HSPA4L PSMD3 ZIC1 ZIC3 IWS1 SMC3 ZIC5 PRELID2 TYW5 TKT GPR153 LRP2 PKP2 EIF3A FLRT1 RIMS2 PREX1	1.31e-06	991	114	19	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	MPO NEPRO APCDD1 SMC1A IWS1 BRAF SMC3 TYW5 CEP41 EIF3A HECTD1 PREX1	8.44e-06	469	114	12	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_100	HSPA4L ZIC1 ZIC3 ZIC5 LRP2 RIMS2	1.66e-05	100	114	6	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_100
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000	HSPA4L NPEPPS SMC1A ABCC9 FMNL2 ZIC1 ZIC3 IWS1 PTPRD SMC3 ZIC5 NPTXR LRP2 KDM7A EIF3A RIMS2 TBP	2.01e-05	986	114	17	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	NSUN4 AMER1 APCDD1 TSHZ2 SMC1A HJURP CAPN6 ABCC9 ADD3 IGFBP5 TULP4 USP40 LRP1 EIF3A FLRT1	2.15e-05	790	114	15	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2	HSPA4L ZIC1 ZIC3 ZIC5 LRP2	4.01e-05	71	114	5	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#2	HSPA4L NPEPPS ZIC3 PPP1R7 NCOR2 UBR5 ZIC5 SHPRH RIMS2 TBP	5.41e-05	395	114	10	Facebase_RNAseq_e8.5_Floor Plate_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#1	HSPA4L ZIC1 ZIC3 ZIC5 LRP2 RIMS2	6.40e-05	127	114	6	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	MPO HSPA4L HJURP CAPN6 FMNL2 ZIC1 ZIC3 IWS1 UBR5 SMC3 TYW5 USP40 LRP2 PKP2 EIF3A RIMS2	7.16e-05	983	114	16	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_1000	NSUN4 APCDD1 TSHZ2 SMC1A HJURP ADD3 CLRN3 LRP1	7.32e-05	256	114	8	gudmap_developingGonad_e14.5_ epididymis_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	APCDD1 HSPA4L SMC1A ZIC1 ZIC3 IWS1 UBR5 SMC3 ZIC5 TYW5 LRP2 PKP2 EIF3A FLRT1 RIMS2 HECTD1	7.69e-05	989	114	16	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3	HSPA4L NPEPPS SMC1A FMNL2 ZIC1 ZIC3 IWS1 PTPRD TULP4 SMC3 NPTXR KDM7A EIF3A RIMS2 TBP	8.67e-05	893	114	15	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5	HSPA4L NPEPPS ZIC1 ZIC3 ZIC5 LRP2 RIMS2	1.21e-04	205	114	7	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	MPO NEPRO APCDD1 IWS1 PPP1R7 UBR5 SMC3 TYW5 KDM7A EIF3A FLRT1	1.38e-04	532	114	11	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_100	HSPA4L ZIC1 ZIC3 LRP2 RIMS2	2.05e-04	100	114	5	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_100
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	HSPA4L SMC1A FMNL2 IWS1 PTPRD SMC3 EIF3A RIMS2	2.08e-04	298	114	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500	MPO HSPA4L ZIC1 ZIC3 IWS1 SMC3 TYW5 PKP2 EIF3A RIMS2	3.28e-04	493	114	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500	HSPA4L ZIC1 ZIC3 ZIC5 PRELID2 TYW5 LRP2 PKP2 FLRT1 RIMS2	3.44e-04	496	114	10	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	NSUN4 AMER1 APCDD1 TSHZ2 SMC1A HJURP ADD3 TULP4 CLRN3 USP40 LRP1 EIF3A FLRT1	3.68e-04	801	114	13	gudmap_developingGonad_e14.5_ epididymis_1000
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAP1 TTYH2 ADD3 DOCK5 SHROOM4 PTPRD PLPP2 LRP2	6.97e-08	194	123	8	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PLPP2 LRP2 PREX1	8.43e-07	185	123	7	b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PLPP2 LRP2 PREX1	9.06e-07	187	123	7	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PLPP2 LRP2 PREX1	9.72e-07	189	123	7	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PLPP2 LRP2 PREX1	1.01e-06	190	123	7	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PLPP2 LRP2 PREX1	1.04e-06	191	123	7	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTYH2 FMNL2 ADD3 DOCK5 PTPRD PLPP2 LRP2	1.37e-06	199	123	7	214a6a267e77e5508867b9eb48c4fbc7855ed0a0
ToppCell	Cerebellum\|World / BrainAtlas - Mouse McCarroll V32	ETFB ZIC1 ZIC3 ZIC5 IL22 CPVL	3.41e-06	147	123	6	dd730224e39571ca2c35042e242a908a02ee377d
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAPKAPK2 ARHGEF10L TKT LRP1 KDM7A FGR	8.12e-06	171	123	6	ed5886d6aa87b2d73469d39dc217227bd4d4c918
ToppCell	Mild/Remission-B_memory-6\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ADAP1 PLPP2 TKT UCKL1 FGR PREX1	9.89e-06	177	123	6	8f2ce5ffc94ca90412cb6899629f322dc778215c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL36B ZIC1 IL22 RIMS1 CADPS2 RIMS2	1.09e-05	180	123	6	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2 PREX1	1.19e-05	183	123	6	5472cdce6d99314d229418412acf1fff6340db7d
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2 PREX1	1.23e-05	184	123	6	5939527d24d299e562e707469c9123890edd76be
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2 PREX1	1.23e-05	184	123	6	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 ELOVL1 DOCK5 SHROOM4 PLPP2 LRP2	1.39e-05	188	123	6	14072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 ELOVL1 DOCK5 SHROOM4 PLPP2 LRP2	1.43e-05	189	123	6	70eea8c94fa56bb15bee8065de47acea156794e9
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 ELOVL1 DOCK5 SHROOM4 PLPP2 LRP2	1.43e-05	189	123	6	b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.48e-05	190	123	6	07f21386ea6eb23416a537d2250e3042efe93fb0
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 ELOVL1 DOCK5 SHROOM4 PLPP2 LRP2	1.48e-05	190	123	6	396b7225c2430db3dc55a3d0db70239b71987229
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DNAH14 PTP4A1 SHROOM4 PTPRD CADPS2 ACSS3	1.52e-05	191	123	6	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOT SMC1A PTPRD IGFBP5 ZBED6 LRP1	1.71e-05	195	123	6	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTYH2 FMNL2 DOCK5 PTPRD PLPP2 LRP2	1.81e-05	197	123	6	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGEF10L ADD3 PLPP2 NXF3 PKP2 CDH17	1.87e-05	198	123	6	a4543d636501a1b5b46c14a661ce9d169947c82c
ToppCell	distal-mesenchymal-Myofibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MYOT ZIC1 CFHR3 IGFBP5 ZIC5 CDH17	1.87e-05	198	123	6	beef5075ba6dcd4d0a447bc4e57efcaf2e93c546
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTYH2 ADD3 DOCK5 PTPRD PLPP2 LRP2	1.97e-05	200	123	6	acdef0b9096c774040948fc75621ff2b08ea2ee8
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	OR7A5 TTYH2 DOCK5 PTPRD PLPP2 LRP2	1.97e-05	200	123	6	3ce8a2db8c25e1169a0a544f644a63104749c5ee
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTYH2 FMNL2 DOCK5 PTPRD PLPP2 LRP2	1.97e-05	200	123	6	091a18d6efed81cab99955c3047f172170f70476
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTYH2 FMNL2 DOCK5 PTPRD PLPP2 LRP2	1.97e-05	200	123	6	3b8513defe25262ab4b492345b2628570eaefd17
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGEF10L VRTN NUDCD1 CPVL ACSS3	5.88e-05	149	123	5	c773c2b9685ec44a35246180a93456c8765353f5
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMBRA1 ITGAV DOCK5 LRP1 CADPS2	6.46e-05	152	123	5	82a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	OR7D4 OR7A5 FMNL2 ARHGEF10L NPTXR	6.66e-05	153	123	5	ee6f4770c6e35d59bdeec5b0ecb10119fa8c3ca5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	OR7D4 OR7A5 FMNL2 ARHGEF10L NPTXR	6.66e-05	153	123	5	a35149a0c8b4ec9ad27cc4b3d34fba3b8714a6a2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	OR7D4 OR7A5 FMNL2 ARHGEF10L NPTXR	6.66e-05	153	123	5	90cd6efda83c0b4b80eae2c90e7ff45dfd936dc2
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 ARHGEF10L DOCK5 LRP1 FGR	8.23e-05	160	123	5	2020b6defbaf5b5db12af37f0103ac028a8ca76e
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 ARHGEF10L DOCK5 LRP1 FGR	8.23e-05	160	123	5	af7cf0dc5fe7c02f7d6c436f6dde766c79ff0eae
ToppCell	Mild/Remission-B_memory-6\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ADAP1 PLPP2 TKT UCKL1 PREX1	9.79e-05	166	123	5	03e1a369d8a83b814def07e29cabb023226b4828
ToppCell	droplet-Lung-LUNG-1m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 ARHGEF10L TKT LRP1 FGR	9.79e-05	166	123	5	dd5944101ef58a9a29aa3eb5c17690119572b8f1
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 ARHGEF10L TKT LRP1 FGR	9.79e-05	166	123	5	8e5e8de51b4dacdadaa5a08279df30b5c7ed3628
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1B CAPN6 GRIK5 RIMS1 RIMS2	1.01e-04	167	123	5	c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell	droplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAP1 MAPKAPK2 ARHGEF10L LRP1 FGR	1.04e-04	168	123	5	00cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAPKAPK2 ARHGEF10L DOCK5 LRP1 FGR	1.04e-04	168	123	5	c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAPKAPK2 ARHGEF10L DOCK5 LRP1 FGR	1.04e-04	168	123	5	c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCell	Smart-seq2-blood_(Smart-seq2)\|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADAP1 ADD3 LRP1 FGR CTSD	1.06e-04	169	123	5	0ee74cc97a2db9cc16dc73424f74747afe13af90
ToppCell	droplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAP1 MAPKAPK2 ARHGEF10L LRP1 FGR	1.06e-04	169	123	5	90c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1B CAPN6 GRIK5 RIMS1 RIMS2	1.06e-04	169	123	5	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLOD5 ETFB TTYH2 PRELID2 LRP1	1.09e-04	170	123	5	75b0486620cab838d3feb1c3aa965b487a906618
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Deuterosomal\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HSPA4L MYCBPAP ZMYND10 CEP41 SPAG17	1.13e-04	171	123	5	52aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL36B ZIC1 RIMS1 CADPS2 RIMS2	1.25e-04	175	123	5	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Macrophage\|GI_small-bowel / Manually curated celltypes from each tissue	FMNL2 ARHGEF10L CFHR3 LRP1 CPVL	1.29e-04	176	123	5	4be270f6bb7da4070f972aca403109751646d155
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAP1 LRP1 EIF3A FGR CTSD	1.32e-04	177	123	5	67cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MED29 PRELID2 USP40 RIMS1 DHTKD1	1.36e-04	178	123	5	89f0537459a321ded956bf70ad56fefc0854f8b0
ToppCell	LPS_only-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAP1 ARHGEF10L LRP1 FGR CPVL	1.39e-04	179	123	5	dc03b9045510eb1bb934329646bb92dd06890ce9
ToppCell	LPS_only-Myeloid-Monocytes,_Macrophages\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAP1 ARHGEF10L LRP1 FGR CPVL	1.39e-04	179	123	5	330c1326ba93bb8f32559ee1cc40e357cc44ad8d
ToppCell	10x5'v1-week_17-19-Hematopoietic-MK-early_MK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GP6 GLOD5 SHROOM4 PKP2 FRMPD3	1.39e-04	179	123	5	d5b9c610c1519804b1753fed1b505293ea590867
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Dendritic_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MED29 PRELID2 USP40 RIMS1 DHTKD1	1.43e-04	180	123	5	710526abedc8e0f9ba19ad69220df4c9468ada8f
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	ABCC9 PTPRD LRP2 CADPS2 ACSS3	1.43e-04	180	123	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.47e-04	181	123	5	a8e9ea73c24109a5d4d28bc0577cc869ad932a4d
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.51e-04	182	123	5	d524ad5cf00f05ee27c9db2ffa2d4e30a1e2e21a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN6 MYCBPAP ZMYND10 LRP2 ACSS3	1.51e-04	182	123	5	587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN6 MYCBPAP ZMYND10 LRP2 ACSS3	1.51e-04	182	123	5	adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TSHZ2 FMNL2 DOCK5 LRP1 RIMS1	1.54e-04	183	123	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.54e-04	183	123	5	93213124e55d1b673dd345188caf8b5bd31d99fe
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.58e-04	184	123	5	f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TKT LRP1 EIF3A FGR CTSD	1.58e-04	184	123	5	fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.63e-04	185	123	5	1d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.63e-04	185	123	5	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.67e-04	186	123	5	d57c40b3fe5cfc87e771df76533d9a3e94678b04
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.67e-04	186	123	5	90eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.67e-04	186	123	5	bd8a9753df219084e19e7f94447856e86608325c
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.71e-04	187	123	5	f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.71e-04	187	123	5	b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.75e-04	188	123	5	60242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMNL2 SHROOM4 UBR5 SHPRH KDM7A	1.75e-04	188	123	5	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMNL2 SHROOM4 UBR5 SHPRH KDM7A	1.75e-04	188	123	5	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMNL2 SHROOM4 UBR5 SHPRH KDM7A	1.75e-04	188	123	5	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.75e-04	188	123	5	b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PREX1	1.75e-04	188	123	5	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSPA4L MYCBPAP IGFBP5 ZMYND10 SPAG17	1.80e-04	189	123	5	fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PREX1	1.80e-04	189	123	5	784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSPA4L MYCBPAP IGFBP5 ZMYND10 SPAG17	1.80e-04	189	123	5	565063f9e3dd79164321f8a394bd12c176baf202
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PREX1	1.80e-04	189	123	5	37ecbd73408d462b47d7e5611f203143e08a2689
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSPA4L MYCBPAP IGFBP5 ZMYND10 SPAG17	1.80e-04	189	123	5	497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCell	COPD-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	ADD3 DOCK5 PKP2 FGR DNMBP	1.84e-04	190	123	5	aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PREX1	1.84e-04	190	123	5	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	COVID-19-Heart-CM_4\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP MAPKAPK2 PLCL2 PKP2 ACSS3	1.84e-04	190	123	5	3729648a17093b438398b82e32bbccc3af7b8c5d
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.84e-04	190	123	5	6b101359f397020a21e2bfd15851cb48e71f4502
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_2\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	APCDD1 ABCC9 ZIC1 ZIC3 LRP2	1.88e-04	191	123	5	06107849463a1ccb78a5ccd3ae31619ef6bedda3
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTYH2 DOCK5 SHROOM4 PLPP2 LRP2	1.88e-04	191	123	5	2110a1dd10730ad7ee7a265fb1716ab3ddafcf4a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PREX1	1.88e-04	191	123	5	f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 TTYH2 DOCK5 SHROOM4 PREX1	1.88e-04	191	123	5	a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSPA4L MYCBPAP IGFBP5 ZMYND10 SPAG17	1.93e-04	192	123	5	b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	ABCC9 DNAH14 LRP2 CADPS2 ACSS3	1.93e-04	192	123	5	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DNAH14 SHROOM4 PTPRD CADPS2 ACSS3	1.93e-04	192	123	5	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	APCDD1 TSHZ2 ABCC9 PTPRD IGFBP5	1.93e-04	192	123	5	20ede290e01ad574afd122d72b59dbc52c595fad
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCC9 PTPRD LRP2 CADPS2 ACSS3	1.98e-04	193	123	5	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	Children_(3_yrs)-Immune-monocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LRRK1 PLCL2 KDM7A CPVL PREX1	1.98e-04	193	123	5	58e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TKT LRP1 FGR CTSD CPVL	1.98e-04	193	123	5	1db487e5f81849740d57cc3e2b5739e8f7581efb
ToppCell	Control-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	TTYH2 SLC25A25 DOCK5 PKP2 DNMBP	1.98e-04	193	123	5	3479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCC9 PTPRD LRP2 CADPS2 ACSS3	1.98e-04	193	123	5	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TKT LRP1 FGR CTSD CPVL	1.98e-04	193	123	5	4fb020f11fd7aff06952bfeaabc79b2c7b8873f6
Disease	Colorectal Carcinoma	MPO AMPD1 ELOA2 MYOT CAPN6 ARHGEF10L PTPRD BRAF LRP1 LRP2 VRTN SPAG17	3.30e-05	702	121	12	C0009402
Disease	response to interferon	ABCC9 PRELID2 RIMS1	1.45e-04	25	121	3	EFO_0007859
Disease	Congenital muscular hypertrophy-cerebral syndrome	SMC1A SMC3	1.65e-04	5	121	2	C1802395
Disease	Cornelia de Lange Syndrome 3	SMC1A SMC3	1.65e-04	5	121	2	C1853099
Disease	Cornelia de Lange Syndrome 1	SMC1A SMC3	1.65e-04	5	121	2	C4551851
Disease	De Lange syndrome	SMC1A SMC3	2.47e-04	6	121	2	cv:C0270972
Disease	Cornelia de Lange syndrome (implicated_via_orthology)	SMC1A SMC3	2.47e-04	6	121	2	DOID:11725 (implicated_via_orthology)
Disease	Schizophrenia	CACNA1B HTR6 AMBRA1 GRIK5 PTPN21 GPR153 PLCL2 LRP1 LRP2 CADPS2 RIMS2 TBP	2.83e-04	883	121	12	C0036341
Disease	erythronate measurement	TKT CDH17	3.46e-04	7	121	2	EFO_0021025
Disease	autism spectrum disorder (implicated_via_orthology)	PKP2 RIMS1 CADPS2 RIMS2 PREX1	4.18e-04	152	121	5	DOID:0060041 (implicated_via_orthology)
Disease	Cornelia De Lange Syndrome	SMC1A SMC3	4.59e-04	8	121	2	C0270972
Disease	Muscle Weakness	AMPD1 MYOT	7.35e-04	10	121	2	C0151786
Disease	monoclonal gammopathy	PTPRD RIMS2 PREX1	1.36e-03	53	121	3	EFO_0000203
Disease	pulse pressure measurement, social deprivation	PLCL2 ACSS3	1.47e-03	14	121	2	EFO_0005763, EFO_0009696
Disease	lymphocyte percentage of leukocytes	MPO ADAP1 PSMD3 LRRK1 DOCK5 UBR5 PLCL2 SETD3 PREX1	1.71e-03	665	121	9	EFO_0007993
Disease	cocaine dependence	NCOR2 POP1 RIMS2	1.76e-03	58	121	3	EFO_0002610
Disease	cholesteryl esters to total lipids in large HDL percentage	ETFB NCOR2 DOCK7	1.85e-03	59	121	3	EFO_0022248
Disease	triglycerides to total lipids in large HDL percentage	ETFB NCOR2 DOCK7	1.94e-03	60	121	3	EFO_0022330
Disease	Cardiomyopathies	MYOT ABCC9 BRAF PKP2	2.05e-03	130	121	4	C0878544
Disease	Benign neoplasm of stomach	BRAF UBR5	2.18e-03	17	121	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	BRAF UBR5	2.18e-03	17	121	2	C0496905
Disease	Carcinoma in situ of stomach	BRAF UBR5	2.18e-03	17	121	2	C0154060
Disease	Myeloid Leukemia	SMC1A SMC3	2.44e-03	18	121	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SMC1A SMC3	2.44e-03	18	121	2	C0023466
Disease	susceptibility to hepatitis A infection measurement	TULP4 FLRT1 SPAG17	2.78e-03	68	121	3	EFO_0008415
Disease	smoking status measurement	NRAP TSHZ2 GRIK5 ADD3 PTPRD OR1I1 TULP4 PRELID2 PLCL2 RIMS1 SETD3 CADPS2	2.95e-03	1160	121	12	EFO_0006527
Disease	Stomach Carcinoma	BRAF UBR5	3.33e-03	21	121	2	C0699791

Protein segments in the cluster

Peptide	Gene	Start	Entry
APEVIRMQDKNPYSF	BRAF	621	P15056
NPIIYPLFMRDFKRA	HTR6	316	P50406
LYGLMVKPIQRFPQF	ARHGEF10L	451	Q9HCE6
PLSPLKYMAQRQQRE	ADD3	421	Q9UEY8
EYLMKRIPQNPRYQH	CEP41	11	Q9BYV8
RQEKPVLEYQMRPLG	AMER1	646	Q5JTC6
GSFLIKPVQRVMRYP	DNMBP	916	Q6XZF7
RRYVFFMNPQKVKPP	ABCC9	191	O60706
FQKAVDRPMLPQEYA	ADAP1	351	O75689
MIQVPRIYDVFRSKN	AMPD1	456	P23109
MRRVFNVLYPMPADQ	AMBRA1	991	Q9C0C7
PFYTNPIMYKIIRAR	DHTKD1	441	Q96HY7
QRARTMALYNPIPVK	CACNA1B	51	Q00975
AKPLTRYMPQNRQSF	CACNA1B	1446	Q00975
RRMQRLIEKYNQPFE	HJURP	31	Q8NCD3
RARVPMPSNKDYVVR	IWS1	751	Q96ST2
RQPAPMSTVLYNRKE	NUDCD1	521	Q96RS6
VTPMLNPFIYSLRNK	OR7A5	281	Q15622
LDIQRLPFYPDMVNR	NXF3	221	Q9H4D5
PPMLYDADQQRIKFI	NCOR2	396	Q9Y618
AAFPGRRVNAKMPVY	ELOA2	501	Q8IYF1
VKYFMNPNRPKVLNV	KDM7A	211	Q6ZMT4
KTRIRMGQYEFPNPE	MAPKAPK2	276	P49137
RIPYPGMNKREVLEQ	FGR	456	P09769
FPAMITPAYQIAKRA	NRAP	241	Q86VF7
ARQNPYPVKAMEVVN	LRRK1	1686	Q38SD2
KGPIMSIYFRDPDRN	GLOD5	136	A6NK44
MSKRNQVSYVRPAEP	KIAA1143	1	Q96AT1
RPPIFEIRMYDAQQQ	LRP1	786	Q07954
FKPRNYQLELALPAM	DDX58	241	O95786
PYDQPLRAFDMINRF	CPVL	451	Q9H3G5
RYQDQAVLFIPAMKR	GP6	66	Q9HCN6
QPFMFRLDNRYQPME	MPO	506	P05164
MPVPELYNRIFRNSF	KIR3DL3	66	Q8N743
EDKMQYLQVPPTRRF	GPR153	381	Q6NV75
QELKASPRMVPRAVY	IGFBP5	201	P24593
AERYKMLIPFSNPRV	NLRP2	186	Q9NX02
KQPIIFENPMYSARD	LRP2	4516	P98164
QQDFDPVQRYKMLIP	MED29	51	Q9NX70
FIPMLNPFIYSIRNK	OR1I1	281	O60431
VTPMLNPFIYSLRNK	OR1J1	281	Q8NGS3
VALSNMNVIDRKPYP	NPEPPSL1	211	A6NEC2
AKYMIGRLRPNFLAV	PLPP2	116	O43688
PDAFKISIPIRNNYM	NPTXR	291	O95502
PKFPAVRLALQNFDM	NSUN4	36	Q96CB9
RPTPDYETVMKQLNR	PTPN21	446	Q16825
ARVDGRPRNPYVKMY	RIMS1	771	Q86UR5
VTPMLNPFIYSLRNK	OR7D4	281	Q8NG98
ARYPVKPQPYEEQMR	RIMS2	371	Q9UQ26
RVNKYPREMLGPVTF	POP1	296	Q99575
PRRPNDIYVNMKTDF	POP7	31	O75817
ENMRRPYFPVAVGKY	CFHR3	36	Q02985
MAPIYLKRLLPVFAQ	HECTD1	516	Q9ULT8
MNPQREAAPKSYAIR	IL36B	1	Q9NZH7
ASFYENIIKAMRPQP	DOCK5	1346	Q9H7D0
NIIKAMRPQPEYFAV	DOCK5	1351	Q9H7D0
DPRYSDPQIKARVAM	DOCK7	1226	Q96N67
MPAYFQRPENALKRA	EIF3A	1	Q14152
PRQMAVFSLPEEVYR	FRMPD3	1496	Q5JV73
MAYPRISVNNVLPVF	CTSD	201	P07339
YRMGFFKRVRPPQEE	ITGAV	1016	P06756
RPEKRATSYQMPLVQ	APCDD1	451	Q8J025
AYPFNAKQPTDMARR	CADPS2	96	Q86UW7
ANRKPFQLRGFMIVY	ELOVL1	51	Q9BW60
MPRPKVLAQYESIQF	DSCR8	81	Q96T75
AMNLPPDKARLLRQY	FMNL2	41	Q96PY5
RNRQKFQPYPMEDIT	DNAH14	1681	Q0VDD8
PPNVRIMFEVQDLKY	DYNC1H1	2336	Q14204
LQMLPINPYRAKEEY	FLRT1	591	Q9NZU1
TILENPYVMRRPNFQ	GRIK5	421	Q16478
RRVLNLPPNTIMEYK	EIF4E2	201	O60573
FLNYRIVEQTPKLPM	CDH17	376	Q12864
VFSAEKVYMVRLRNP	CAPN6	271	Q9Y6Q1
DPQYRRKVMLALPSV	PPP1R7	336	Q15435
VALSNMNVIDRKPYP	NPEPPS	211	P55786
RPVKDRLGNRPEMNY	PHAX	201	Q9H814
FKNRLVNIMPYESTR	PTPRD	1671	P23468
PMLNPFIYSLRNRDM	OR1A1	281	Q9P1Q5
VTPLLNPFIYSMRNK	OR1P1	296	Q8NH06
AIPMISKLRYNPRFD	SMC3	606	Q9UQE7
VTPMLNPFIYSLRNK	OR7A10	281	O76100
RLNEPRYATLPNIMK	ETFB	186	P38117
QEVARIQPMPYFKDF	NEPRO	206	Q6NW34
NYNKRFLARVFPSPM	PLCL2	666	Q9UPR0
VKDQMPQGAPRLYRL	PREX1	1636	Q8TCU6
REYYRQQMEEKAPLP	SETD3	486	Q86TU7
RNQKRYMAIPSPLVA	SHPRH	796	Q149N8
REKLVFGMVSRYLPQ	SHROOM4	1431	Q9ULL8
VTPMLNPFIYSLRNK	OR7D2	281	Q96RA2
FQPYMQEVVPFLARL	IL22	111	Q9GZX6
RVKRIFYQNVPSPAM	IL9R	296	Q01113
METPQKEAYLAPVRR	IQANK1	96	A8MXQ7
SPSQFMPLVVDYRQK	PNPT1	91	Q8TCS8
EILQARFPMPRYINT	SEC23B	696	Q15437
TQNYLMDIKNRIIPP	SPAG17	1896	Q6Q759
KILIYNRPNMEAVPL	ACSS3	251	Q9H6R3
YQRKQEQRKPMEYAP	CLRN3	206	Q8NCR9
YRGLAPNFMKVIPAV	SLC25A25	436	Q6KCM7
RKISMDYINLPVFNP	TULP4	646	Q9NRJ4
PGAFFRYMRQPIKQE	ZIC3	236	O60481
KYLPSLEMFRQRFRQ	ZSCAN21	36	Q9Y5A6
LQFRQPSLKRSLMPY	PSMD3	346	O43242
MRYKSQDPRNPHNDR	TKT	56	P29401
QTERIRLPYELQKMP	HSPA4L	81	O95757
EYNPKRFAAVIMRIR	TBP	191	P20226
MLFGRNPRYENVPLI	TTYH2	486	Q9BSA4
IRTPVVEKQMYFPLQ	TERB2	151	Q8NHR7
RQYMTLPAKAEEARP	MYCBPAP	616	Q8TBZ2
EQVVASFLRKYPNPM	PRELID2	16	Q8N945
INYNCVAPGKRFRPM	SMC1A	1111	Q14683
DPKTRAMRENPYANA	SLU7	286	O95391
MAQSDFLYPENPKRR	SMCO3	1	A2RU48
PKDRQYVVRLMAPFN	YJU2	26	Q9BW85
MPRRKQQAPKRAAGY	TSHZ2	1	Q9NRE2
GAFFRYMRQPIKQEL	ZIC1	211	Q15915
PAFQRFMQIVAPDYR	ZBED6	431	P86452
KPSFDQYIQPTMRLA	UCKL1	261	Q9NWZ5
RVEDFKPQNTFPIYM	ZMYND10	91	O75800
NIYSIYPMRNLKIRP	VRTN	186	Q9H8Y1
YPMRNLKIRPYFNRV	VRTN	191	Q9H8Y1
MLFYRKSQLQRPPEA	USP40	476	Q9NVE5
RSRKVKEQYQDVPMP	PKP2	651	Q99959
RPAPVEVTYKNMRFL	PTP4A1	6	Q93096
FRPFEGPRRNKEVMY	TBK1	221	Q9UHD2
REQFMQHLYPQRKPL	TYW5	16	A2RUC4
LYPRVQAMQPAFASK	UBR5	2401	O95071
AGAFLRYMRQPIKQE	ZIC5	381	Q96T25
KFYPPRFIQVPENMS	MYOT	246	Q9UBF9