Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH12 DNAH17 DNAH5 DNAH6 DYNC1H1 DNAH11

1.48e-09181356GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH12 DNAH17 DNAH5 DNAH6 DYNC1H1 DNAH11

2.85e-08281356GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH12 DNAH17 DNAH5 DNAH6 DYNC1H1 DNAH11

1.67e-07371356GO:0045505
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAL4 DNAH12 DNAH17 DNAH5 DNAH6 DYNC1H1 DNAH11

4.64e-07701357GO:0003777
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAL4 DNAH12 DNAH17 DNAH5 DNAH6 DYNC1H1 DNAH11

1.56e-051181357GO:0003774
GeneOntologyMolecularFunctionphosphatidylinositol phospholipase C activity

CCR1 PLCB3 PLCB4 PLCL1

2.66e-05261354GO:0004435
GeneOntologyMolecularFunctionphospholipase C activity

CCR1 PLCB3 PLCB4 PLCL1

4.16e-05291354GO:0004629
GeneOntologyMolecularFunctioncalcium-dependent cysteine-type endopeptidase activity

CAPN12 CAPN8 CAPN15

1.92e-04171353GO:0004198
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA2 FIGNL2 ABCC5 ATP13A5 ABCA9 DNAH12 NAV1 DNAH5 DNAH6 DYNC1H1 DNAH11

2.07e-0444113511GO:0016887
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

IFT27 ABCA2 FIGNL2 ABCC5 ATP13A5 DNAJC27 RAB40A ABCA9 DNAH12 RAB40AL NAV1 DNAH5 DNAH6 DYNC1H1 DNAH11

2.43e-0477513515GO:0017111
GeneOntologyMolecularFunctionATP-dependent activity

ABCA2 FIGNL2 ABCC5 ATP13A5 ABCA9 DNAL4 DNAH12 DNAH17 NAV1 DNAH5 DNAH6 DYNC1H1 DNAH11

2.74e-0461413513GO:0140657
GeneOntologyMolecularFunctionlipase activity

PNLIPRP1 LIPC CCR1 PLCB3 PLCB4 PLCL1

3.54e-041381356GO:0016298
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

PDE6B CCR1 PLCB3 PLCB4 PLCL1

5.14e-04971355GO:0008081
GeneOntologyMolecularFunctionpyrophosphatase activity

IFT27 ABCA2 FIGNL2 ABCC5 ATP13A5 DNAJC27 RAB40A ABCA9 DNAH12 RAB40AL NAV1 DNAH5 DNAH6 DYNC1H1 DNAH11

5.59e-0483913515GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

IFT27 ABCA2 FIGNL2 ABCC5 ATP13A5 DNAJC27 RAB40A ABCA9 DNAH12 RAB40AL NAV1 DNAH5 DNAH6 DYNC1H1 DNAH11

5.65e-0484013515GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

IFT27 ABCA2 FIGNL2 ABCC5 ATP13A5 DNAJC27 RAB40A ABCA9 DNAH12 RAB40AL NAV1 DNAH5 DNAH6 DYNC1H1 DNAH11

5.65e-0484013515GO:0016818
GeneOntologyMolecularFunctionphospholipase activity

LIPC CCR1 PLCB3 PLCB4 PLCL1

1.07e-031141355GO:0004620
GeneOntologyCellularComponentdynein complex

DNAL4 DNAH12 DNAH17 DNAH5 DNAH6 DYNC1H1 DNAH11

5.51e-08541357GO:0030286
GeneOntologyCellularComponentmicrotubule associated complex

ACTR1B ACTR1A DNAL4 DNAH12 DNAH17 DNAH5 DNAH6 DYNC1H1 DNAH11

1.04e-061611359GO:0005875
GeneOntologyCellularComponentaxonemal dynein complex

DNAH12 DNAH17 DNAH5 DNAH6

1.89e-05251354GO:0005858
GeneOntologyCellularComponent9+0 motile cilium

DNAH5 DNAH11

6.11e-0461352GO:0097728
GeneOntologyCellularComponentmicrotubule

MAP9 DPYSL2 DNAL4 NEK2 DNAH12 DNAH17 NAV1 DNAH5 DNAH6 DYNC1H1 DNAH11

6.95e-0453313511GO:0005874
GeneOntologyCellularComponent9+2 motile cilium

IFT27 DNAH12 DNAH17 SLC9B2 DNAH5 DNAH6 DNAH11

9.15e-042381357GO:0097729
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH5 DNAH6 DYNC1H1 DNAH11

2.99e-08141315IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH5 DNAH6 DYNC1H1 DNAH11

2.99e-08141315IPR013602
DomainDHC_N2

DNAH12 DNAH5 DNAH6 DYNC1H1 DNAH11

2.99e-08141315PF08393
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH5 DNAH6 DYNC1H1 DNAH11

2.99e-08141315IPR011704
DomainAAA_8

DNAH12 DNAH5 DNAH6 DYNC1H1 DNAH11

2.99e-08141315PF12780
DomainAAA_5

DNAH12 DNAH5 DNAH6 DYNC1H1 DNAH11

2.99e-08141315PF07728
DomainDHC_fam

DNAH12 DNAH5 DNAH6 DYNC1H1 DNAH11

4.46e-08151315IPR026983
DomainDynein_heavy

DNAH12 DNAH5 DNAH6 DYNC1H1 DNAH11

4.46e-08151315PF03028
DomainDynein_heavy_dom

DNAH12 DNAH5 DNAH6 DYNC1H1 DNAH11

4.46e-08151315IPR004273
DomainAAA

ABCA2 FIGNL2 ABCC5 ABCA9 DNAH12 NAV1 DNAH5 DNAH6 DYNC1H1 DNAH11

7.06e-0814413110SM00382
DomainAAA+_ATPase

ABCA2 FIGNL2 ABCC5 ABCA9 DNAH12 NAV1 DNAH5 DNAH6 DYNC1H1 DNAH11

7.06e-0814413110IPR003593
DomainDynein_HC_stalk

DNAH5 DNAH6 DYNC1H1 DNAH11

2.19e-06141314IPR024743
DomainMT

DNAH5 DNAH6 DYNC1H1 DNAH11

2.19e-06141314PF12777
Domain-

IFT27 ABCA2 GTPBP6 FIGNL2 ABCC5 DNAJC27 RAB40A TEP1 AAGAB ABCA9 DNAH12 RAB40AL NAV1 SULT4A1 DNAH5 DNAH6 DYNC1H1 DNAH11

4.70e-06746131183.40.50.300
DomainDHC_N1

DNAH5 DYNC1H1 DNAH11

1.84e-0581313PF08385
DomainDynein_heavy_dom-1

DNAH5 DYNC1H1 DNAH11

1.84e-0581313IPR013594
DomainSpectrin

SPTA1 ACTN4 CCDC141 UTRN

1.85e-05231314PF00435
DomainP-loop_NTPase

IFT27 ABCA2 GTPBP6 FIGNL2 ABCC5 DNAJC27 RAB40A TEP1 AAGAB ABCA9 DNAH12 RAB40AL NAV1 SULT4A1 DNAH5 DNAH6 DYNC1H1 DNAH11

2.65e-0584813118IPR027417
DomainSpectrin_repeat

SPTA1 ACTN4 CCDC141 UTRN

4.79e-05291314IPR002017
DomainArp1

ACTR1B ACTR1A

4.88e-0521312IPR029909
Domain-

CAPN12 SPTA1 ACTN4 CAPN8 PLCB3 PLCB4 TESC PLCL1 UTRN

9.50e-0526113191.10.238.10
DomainCalpain_cysteine_protease

CAPN12 CAPN8 CAPN15

1.16e-04141313IPR022684
DomainEF-hand_like

PLCB3 PLCB4 PLCL1

1.44e-04151313PF09279
DomainPeptidase_C2

CAPN12 CAPN8 CAPN15

1.44e-04151313PF00648
DomainPI-PLC-Y

PLCB3 PLCB4 PLCL1

1.44e-04151313PF00387
DomainPLCYc

PLCB3 PLCB4 PLCL1

1.44e-04151313SM00149
DomainCysPc

CAPN12 CAPN8 CAPN15

1.44e-04151313SM00230
DomainPeptidase_C2_calpain_cat

CAPN12 CAPN8 CAPN15

1.44e-04151313IPR001300
DomainPLipase_C_Pinositol-sp_Y

PLCB3 PLCB4 PLCL1

1.44e-04151313IPR001711
DomainPIPLC_Y_DOMAIN

PLCB3 PLCB4 PLCL1

1.44e-04151313PS50008
DomainCALPAIN_CAT

CAPN12 CAPN8 CAPN15

1.44e-04151313PS50203
DomainPI-PLC_fam

PLCB3 PLCB4 PLCL1

1.44e-04151313IPR001192
DomainPLC_EF-hand-like

PLCB3 PLCB4 PLCL1

1.44e-04151313IPR015359
DomainPLC-beta_CS

PLCB3 PLCB4

1.46e-0431312IPR009535
DomainDUF1154

PLCB3 PLCB4

1.46e-0431312PF06631
DomainEF-hand-dom_pair

CAPN12 SPTA1 ACTN4 CAPN8 PLCB3 PLCB4 TESC PLCL1 UTRN

1.94e-042871319IPR011992
DomainPI-PLC-X

PLCB3 PLCB4 PLCL1

2.55e-04181313PF00388
DomainPLCXc

PLCB3 PLCB4 PLCL1

2.55e-04181313SM00148
DomainPLC-beta

PLCB3 PLCB4

2.90e-0441312IPR016280
DomainPIPLC_X_DOMAIN

PLCB3 PLCB4 PLCL1

3.01e-04191313PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCB3 PLCB4 PLCL1

3.01e-04191313IPR000909
DomainSOCS

WSB1 RAB40A RAB40AL

3.52e-04201313SM00253
Domain-

PLCB3 PLCB4 PLCL1

6.93e-042513133.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

PLCB3 PLCB4 PLCL1

6.93e-04251313IPR017946
DomainEFhand_Ca_insen

SPTA1 ACTN4

7.19e-0461312PF08726
DomainEF-hand_Ca_insen

SPTA1 ACTN4

7.19e-0461312IPR014837
DomainTHIOL_PROTEASE_CYS

CAPN12 CAPN8 CAPN15

7.79e-04261313PS00139
DomainTHIOL_PROTEASE_ASN

CAPN12 CAPN8 CAPN15

8.72e-04271313PS00640
DomainTHIOL_PROTEASE_HIS

CAPN12 CAPN8 CAPN15

8.72e-04271313PS00639
DomainPept_cys_AS

CAPN12 CAPN8 CAPN15

9.72e-04281313IPR000169
DomainWD40_repeat_CS

WSB1 WDR7 TEP1 CDC40 STRAP PAK1IP1

1.06e-031641316IPR019775
DomainCH

ACTN4 LMO7 TAGLN3 UTRN

1.12e-03651314SM00033
DomainSPEC

SPTA1 ACTN4 UTRN

1.44e-03321313SM00150
DomainSpectrin/alpha-actinin

SPTA1 ACTN4 UTRN

1.44e-03321313IPR018159
DomainCH

ACTN4 LMO7 TAGLN3 UTRN

1.48e-03701314PF00307
Domain-

ACTN4 LMO7 TAGLN3 UTRN

1.56e-037113141.10.418.10
DomainRAB

IFT27 DNAJC27 RAB40A RAB40AL

1.73e-03731314PS51419
DomainCH

ACTN4 LMO7 TAGLN3 UTRN

1.73e-03731314PS50021
DomainCH-domain

ACTN4 LMO7 TAGLN3 UTRN

1.91e-03751314IPR001715
DomainMBT

MBTD1 PHF20L1

2.12e-03101312PF02820
DomainLipase/vitellogenin

PNLIPRP1 LIPC

2.12e-03101312IPR013818
DomainMbt

MBTD1 PHF20L1

2.12e-03101312IPR004092
DomainTAG_lipase

PNLIPRP1 LIPC

2.12e-03101312IPR000734
DomainLipase

PNLIPRP1 LIPC

2.12e-03101312PF00151
DomainLipase_N

PNLIPRP1 LIPC

2.12e-03101312IPR033906
DomainLipase_LIPH

PNLIPRP1 LIPC

2.12e-03101312IPR016272
DomainSOCS_box

WSB1 RAB40A RAB40AL

2.38e-03381313PF07525
DomainSOCS_box

WSB1 RAB40A RAB40AL

2.56e-03391313SM00969
DomainSOCS_box

WSB1 RAB40A RAB40AL

2.56e-03391313IPR001496
DomainSOCS

WSB1 RAB40A RAB40AL

2.56e-03391313PS50225
DomainPNMA

PNMA8B PNMA8A

2.58e-03111312IPR026523
DomainSM22_calponin

LMO7 TAGLN3

2.58e-03111312IPR003096
DomainPNMA

PNMA8B PNMA8A

2.58e-03111312PF14893
Domaincalpain_III

CAPN12 CAPN8

3.08e-03121312SM00720
DomainC2_III

CAPN12 CAPN8

3.08e-03121312IPR033883
DomainABC_A

ABCA2 ABCA9

3.08e-03121312IPR026082
DomainCalpain_III

CAPN12 CAPN8

3.08e-03121312IPR022683
DomainCalpain_III

CAPN12 CAPN8

3.62e-03131312PF01067
DomainCalpain_domain_III

CAPN12 CAPN8

3.62e-03131312IPR022682
DomainNa_H_Exchanger

SLC9A2 SLC9B2

4.20e-03141312PF00999
DomainCation/H_exchanger

SLC9A2 SLC9B2

4.20e-03141312IPR006153
Domain-

RNASEH2A POLG ESRP2

4.37e-034713133.30.420.10
DomainABC_tran

ABCA2 ABCC5 ABCA9

4.63e-03481313PF00005
DomainABC_TRANSPORTER_2

ABCA2 ABCC5 ABCA9

4.63e-03481313PS50893
DomainABC_TRANSPORTER_1

ABCA2 ABCC5 ABCA9

4.91e-03491313PS00211
DomainABC_transporter-like

ABCA2 ABCC5 ABCA9

5.20e-03501313IPR003439
DomainActin_CS

ACTR1B ACTR1A

5.49e-03161312IPR004001
DomainACTINS_2

ACTR1B ACTR1A

6.20e-03171312PS00432
DomainLH2

PNLIPRP1 LIPC

6.94e-03181312SM00308
DomainActin/actin-like_CS

ACTR1B ACTR1A

6.94e-03181312IPR020902
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

ACTR1B ACTR1A DNAL4 DNAH12 DNAH17 DNAH5 DNAH6 DNAH11

6.86e-1227968M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

ACTR1B ACTR1A DNAL4 DNAH12 DNAH17 DNAH5 DNAH6 DNAH11

4.10e-1043968M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

ACTR1B ACTR1A DNAL4 DNAH12 DNAH17 DNAH5 DNAH6 DNAH11

6.03e-1045968M47670
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH12 DNAH17 DNAH5 DNAH6 DYNC1H1 DNAH11

9.36e-121413669373155
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP13 DPYSL2 ABCA2 GTPBP6 STUB1 STAG1 POLG ABCC5 ACTN4 USP9Y LMO7 EIF3C HARS1 CABIN1 SULT4A1 UTRN TOP1 SMYD3 DYNC1H1

6.70e-0712851361935914814
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZHX3 STAG1 DCUN1D5 POLH YY1 MIER1 CASZ1 SETDB2 TRIR PHF20L1 CENPV CABIN1 TOP1

8.53e-076081361336089195
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

ABCA2 ANKFY1 STUB1 BZW2 ACTN4 ACTR1A IGF2BP1 PAPOLA STRAP TBC1D12 TOP1 CAPN15

9.05e-075131361225798074
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH12 DNAH5 DNAH11

2.02e-06713639256245
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH5 DNAH11

2.02e-067136331178125
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MAP9 DPYSL2 ACAT1 WDR7 SPTA1 ACTN4 JMY PNMA8B ACTR1A LMO7 TAGLN3 NAV1 PLCL1 EIF3C DNAH6 UTRN TOP1 DYNC1H1 DNAH11

3.25e-0614311361937142655
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ABCA2 COPG1 ACAT1 SPTA1 ACTN4 ACTR1A STRAP LPGAT1 HARS1 CACYBP UTRN CCDC9 TOP1 DYNC1H1

3.66e-068071361430575818
Pubmed

DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.

YY1 EIF3C DNAH6 TOP1

1.07e-0535136424515614
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ANKFY1 COPG1 ACAT1 ACTN4 GLOD4 SLC38A1 ACTR1A IGF2BP1 CDC40 STRAP CENPV EIF3C HARS1 PAK1IP1 CACYBP DNAH5 TOP1 DYNC1H1

1.19e-0514251361830948266
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

STAG1 COPG1 WEE1 NSMCE3 FABP3 ACTR1B ACTR1A NEK2 IGF2BP1 PHF20L1 CDC40 STRAP EIF3C NEURL4 CCDC9 DYNC1H1

1.23e-0511551361620360068
Pubmed

Loss of gene function as a consequence of human papillomavirus DNA integration.

CASZ1 LIPC

1.52e-052136222262398
Pubmed

YY1 mediated DCUN1D5 transcriptional activation promotes triple-negative breast cancer progression by targeting FN1/PI3K/AKT pathway.

DCUN1D5 YY1

1.52e-052136238831379
Pubmed

PSMB8 and PBK as potential gastric cancer subtype-specific biomarkers associated with prognosis.

PSMB8 PBK

1.52e-052136226894977
Pubmed

Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins.

ACTR1B ACTR1A

1.52e-05213627696711
Pubmed

Phospholipase Cbeta 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons.

PLCB3 PLCB4

1.52e-052136217114052
Pubmed

Structure-Based Design of a Novel SMYD3 Inhibitor that Bridges the SAM-and MEKK2-Binding Pockets.

SMYD3 MAP3K2

1.52e-052136227066749
Pubmed

The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing.

GPD1 FMO5

1.52e-052136226049045
Pubmed

Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.

DNAH5 DNAH11

1.52e-052136232357925
Pubmed

Complementary stripes of phospholipase Cbeta3 and Cbeta4 expression by Purkinje cell subsets in the mouse cerebellum.

PLCB3 PLCB4

1.52e-052136216566000
Pubmed

Ciliary defects and genetics of primary ciliary dyskinesia.

DNAH5 DNAH11

1.52e-052136219410201
Pubmed

Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase.

MAP2K7 MAP3K2

1.52e-05213629372971
Pubmed

A hypomorphic lsd1 allele results in heart development defects in mice.

B4GALT6 LRP6 TESC

3.16e-0516136323637775
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH12 DNAH5 DNAH6 DYNC1H1

3.50e-054713648812413
Pubmed

High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.

NEK2 NAV1 CACYBP UTRN

4.48e-0550136429560723
Pubmed

Disruption of the dynein-dynactin complex unveils motor-specific functions in osteoclast formation and bone resorption.

DYNC1H1 DNAH11

4.54e-053136222887640
Pubmed

Human oncoprotein 5MP suppresses general and repeat-associated non-AUG translation via eIF3 by a common mechanism.

BZW2 EIF3C

4.54e-053136234260931
Pubmed

A Transition-State Perspective on Y-Family DNA Polymerase η Fidelity in Comparison with X-Family DNA Polymerases λ and β.

POLG POLH

4.54e-053136230839203
Pubmed

Lysine methylation in cancer: SMYD3-MAP3K2 teaches us new lessons in the Ras-ERK pathway.

SMYD3 MAP3K2

4.54e-053136225382779
Pubmed

Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.

DNAH12 DYNC1H1

4.54e-05313628666668
Pubmed

CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.

STUB1 MAP3K2

4.54e-053136220588253
Pubmed

Expression profiling of 519 kinase genes in matched malignant peripheral nerve sheath tumor/plexiform neurofibroma samples is discriminatory and identifies mitotic regulators BUB1B, PBK and NEK2 as overexpressed with transformation.

PBK NEK2

4.54e-053136223370767
Pubmed

DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia.

DNAH5 DNAH6

4.54e-053136226918822
Pubmed

NHE10, an osteoclast-specific member of the Na+/H+ exchanger family, regulates osteoclast differentiation and survival [corrected].

SLC9A2 SLC9B2

4.54e-053136218269914
Pubmed

Functional genomics identifies therapeutic targets for MYC-driven cancer.

WEE1 POLH PBK NEK2 MAP2K7

5.47e-05103136522623531
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ZHX3 STUB1 WEE1 NSMCE3 YY1 MIER1 PAPOLA LMO7 PLCB3 EIF3C PAK1IP1 CCDC9

5.56e-057741361215302935
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

DPYSL2 ANKFY1 STUB1 COPG1 RNASEH2A BZW2 PSMB8 ACTN4 ACTR1B ACTR1A PAPOLA STRAP PLCB3 EIF3C HARS1 CACYBP DYNC1H1

5.61e-0514551361722863883
Pubmed

Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.

PDE6B PLCB3 PLCB4

7.39e-0521136330270038
Pubmed

High-throughput mapping of a dynamic signaling network in mammalian cells.

WSB1 STUB1 WEE1 PBK CDC40 STRAP PAK1IP1

7.74e-05260136715761153
Pubmed

Noncanonical function of MEKK2 and MEK5 PB1 domains for coordinated extracellular signal-regulated kinase 5 and c-Jun N-terminal kinase signaling.

MAP2K7 MAP3K2

9.06e-054136217452462
Pubmed

Ift25 is not a cystic kidney disease gene but is required for early steps of kidney development.

IFT27 DNAH5

9.06e-054136229626631
Pubmed

Patterns of expression for the mRNA corresponding to the four isoforms of phospholipase Cbeta in mouse brain.

PLCB3 PLCB4

9.06e-05413629753089
Pubmed

Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.

WSB1 STUB1

9.06e-054136227273569
Pubmed

Phospholipase C-β1 potentiates glucose-stimulated insulin secretion.

PLCB3 PLCB4

9.06e-054136231268747
Pubmed

KDM1A-mediated upregulation of METTL3 ameliorates Alzheimer's disease via enhancing autophagic clearance of p-Tau through m6A-dependent regulation of STUB1.

STUB1 IGF2BP1

9.06e-054136236587923
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAH5 DNAH11

9.06e-054136218492703
Pubmed

PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.

PLCB3 PLCB4

9.06e-054136223006664
Pubmed

Phospholipase C isozymes selectively couple to specific neurotransmitter receptors.

PLCB3 PLCB4

9.06e-05413629305844
Pubmed

Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation.

PLCB3 PLCB4

9.06e-054136215174099
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

COPG1 ACTN4 LMO7 UTRN DYNC1H1

1.04e-04118136527377895
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

DPYSL2 ACAT1 ACTN4 LMO7 UTRN DYNC1H1

1.10e-04191136633762435
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

DPYSL2 COPG1 ACAT1 PRXL2A ACTR1A IGF2BP1 LMO7 CENPV EIF3C UTRN DYNC1H1

1.17e-047111361133022573
Pubmed

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

IFT27 DNAH5 DNAH11

1.26e-0425136327340223
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

DPYSL2 PBK ACTN4 ACTR1A IGF2BP1 STRAP EIF3C HARS1 DNAH6 UTRN TOP1 DYNC1H1

1.30e-048471361235235311
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CAPN12 CAPN8 NEK2 MTMR6 DNAH17 PLCB3 PLCL1 EIF3C HARS1 DNAH5 DNAH11

1.47e-047301361134857952
Pubmed

SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.

SMYD3 MAP3K2

1.51e-045136224847881
Pubmed

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.

DNAH5 DNAH11

1.51e-045136222499950
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH5 DNAH11

1.51e-045136226909801
Pubmed

Rab40b and Tks5 interact at invadopodia during metastasis.

RAB40A RAB40AL

1.51e-045136227909076
Pubmed

Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation.

MAP2K7 MAP3K2

1.51e-045136210713157
Pubmed

LC3 and STRAP regulate actin filament assembly by JMY during autophagosome formation.

JMY STRAP

1.51e-045136230420355
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

ZHX3 ACTN4 ACTR1B ACTR1A IGF2BP1 PAPOLA LMO7 UTRN DYNC1H1

1.78e-04506136930890647
Pubmed

Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.

ABCA2 ACAT1 LIPC

1.98e-0429136320167577
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

ANKFY1 COPG1 ACTN4 ACTR1A IGF2BP1 STRAP EIF3C CACYBP MAP2K7 DYNC1H1

2.16e-046381361033239621
Pubmed

Expression and immunohistochemical localization of eight phospholipase C isoforms in adult male mouse cerebellar cortex.

PLCB3 PLCB4

2.25e-04613628739298
Pubmed

Gene structure, chromosomal localization, and expression pattern of Capn12, a new member of the calpain large subunit gene family.

CAPN12 ACTN4

2.25e-046136210964513
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH5 DNAH11

2.25e-046136233347437
Pubmed

Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets.

PLCB3 PLCB4

2.25e-04613622841328
Pubmed

Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders.

SLC38A1 PLCL1

2.25e-046136220308991
Pubmed

Proline-rich motifs of the Na+/H+ exchanger 2 isoform. Binding of Src homology domain 3 and role in apical targeting in epithelia.

SPTA1 SLC9A2

2.25e-046136210187839
Pubmed

Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes.

ACTR1A DYNC1H1

2.25e-046136211483508
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

PSMB8 ACTN4 CAPN8 ACTR1B STRAP EIF3C UTRN TOP1 DYNC1H1

2.80e-04538136928524877
Pubmed

Reevaluating human gene annotation: a second-generation analysis of chromosome 22.

IFT27 DNAL4 SULT4A1

2.93e-0433136312529303
Pubmed

Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.

ACAT1 ACTR1B DYNC1H1

2.93e-0433136326025364
Pubmed

CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.

STUB1 CACYBP

3.15e-047136231754404
Pubmed

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.

DNAH17 DNAH11

3.15e-047136233139725
Pubmed

Loss of β-carotene 15,15'-oxygenase in developing mouse tissues alters esterification of retinol, cholesterol and diacylglycerols.

ACAT1 BCO1

3.15e-047136223988655
Pubmed

Genetic dissection of gustatory sensitivity to bitterness (sucrose octaacetate) in mice.

PLCB3 PLCB4

3.15e-047136210609087
Pubmed

Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1.

ACTR1B ACTR1A

3.15e-047136212857853
Pubmed

Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.

ABCA2 PNLIPRP1 SPTA1 PRRG3

3.39e-0484136415203218
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

USP13 COPG1 USP9Y TOP1

3.87e-0487136417148452
Pubmed

Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity.

MAP2K7 MAP3K2

4.19e-048136212659851
Pubmed

Binding of phosphatase inhibitor-2 to prolyl isomerase Pin1 modifies specificity for mitotic phosphoproteins.

WEE1 NEK2

4.19e-048136218062707
Pubmed

Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis.

USP13 STUB1

4.19e-048136226280536
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

STUB1 COPG1 PBK ACTN4 GLOD4 YY1 IGF2BP1 TRIR STRAP NAV1 PLCB3 EIF3C CACYBP TOP1 DYNC1H1

4.43e-0414151361528515276
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

COPG1 BZW2 ACTN4 ACTR1A IGF2BP1 STRAP LMO7 TOP1 DYNC1H1

4.82e-04580136935676659
Pubmed

O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma.

COPG1 ACAT1 ACTN4 IGF2BP1 PAK1IP1 DYNC1H1

5.09e-04254136636604567
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

PLEKHS1 ACTN4 YY1 ACTR1B ACTR1A STRAP LMO7 CENPV EIF3C PAK1IP1 TOP1

5.17e-048471361135850772
Pubmed

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.

ACTR1A LRP6

5.37e-049136211357136
Pubmed

Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase C nuclear pathway in the Jurkat T cell line.

PLCB3 PLCB4

5.37e-04913627589147
Pubmed

A genome-wide association study identifies novel loci associated with susceptibility to chronic myeloid leukemia.

WSB1 RMND1

5.37e-049136221540461
Pubmed

Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.

PLCB3 PLCB4

5.37e-049136210501179
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

DPYSL2 STUB1 ACAT1 CASZ1 IGF2BP1 STRAP DYNC1H1

5.42e-04358136732460013
Pubmed

Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.

ACAT1 ACTN4 IGF2BP1 STRAP EIF3C TOP1

5.53e-04258136621081666
Pubmed

The SOCS box: a tale of destruction and degradation.

WSB1 RAB40A RAB40AL

5.59e-0441136312076535
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

STUB1 COPG1 BZW2 KLHL38 DNAH17 CACYBP SMYD3

5.88e-04363136725036637
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

STUB1 USP9Y GGCX IGF2BP1 STRAP ALDH1L2 LPGAT1 HARS1 TOP1 DYNC1H1

5.88e-047251361027025967
Pubmed

Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.

DPYSL2 IGF2BP1 DYNC1H1

6.44e-0443136336950384
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

ZHX3 USP13 DPYSL2 STUB1 ACAT1 NSMCE3 YY1 TRIR PAPOLA PAK1IP1 CACYBP TOP1

6.56e-0410141361232416067
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

ACAT1 ACTN4 SLC38A1 IGF2BP1 EIF3C CACYBP TOP1 DYNC1H1

6.62e-04484136831995728
GeneFamilyDyneins, axonemal

DNAL4 DNAH12 DNAH17 DNAH5 DNAH6 DNAH11

1.33e-1017886536
GeneFamilyC2 domain containing|Calpains

CAPN12 CAPN8 CAPN15

4.86e-0515883975
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCB3 PLCB4 PLCL1

1.02e-0419883832
GeneFamilyParaneoplastic Ma antigens

PNMA8B PNMA8A

1.25e-0311882671
GeneFamilyWD repeat domain containing

WSB1 WDR7 TEP1 CDC40 STRAP PAK1IP1

1.76e-03262886362
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA9

2.05e-0314882805
CoexpressionCHICAS_RB1_TARGETS_SENESCENT

DONSON RNASEH2A WEE1 PSMB8 PRXL2A YY1 TAGLN3 SEL1L3 NAV1 CENPV CACYBP TOP1 DYNC1H1

7.52e-0656513513M2125
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C10orf67 PLEKHS1 NEK2 DNAH12 DNAH5 FBXO15 DNAH11

1.19e-061761367dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAG1 PSMB8 YY1 MIER1 LMO7 PLCB4 UTRN

1.28e-06178136701dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BZW2 CASZ1 SLC38A1 DNAH17 SLC9B2 LPGAT1 PRRG3

1.33e-06179136742f3c040f504a91cc69292d39d22b5715c12526f
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BZW2 CASZ1 SLC38A1 DNAH17 SLC9B2 LPGAT1 PRRG3

1.33e-061791367063c05753ef1b4a18bc1ebbcae62c8cd25d11070
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC5 PLEKHS1 CAPN8 LMO7 SEL1L3 PLCL1 DNAH5

1.48e-061821367215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell(12)_SLC16A7+|World / shred by cell type by condition

ABCA9 LINC00696 IGF2BP1 DNAH12 DNAH5 DNAH6 DNAH11

2.05e-061911367e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

ABCC5 PLEKHS1 CAPN8 LMO7 SEL1L3 PLCL1 DNAH5

2.19e-0619313672bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

PLEKHS1 DNAH12 LMO7 PLCB4 DNAH5 DNAH6 DNAH11

2.35e-061951367fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

PLEKHS1 DNAH12 LMO7 PLCB4 DNAH5 DNAH6 DNAH11

2.35e-061951367eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT27 WEE1 DNAH12 DNAH5 DNAH6 FBXO15 DNAH11

2.51e-061971367d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC5 PLEKHS1 CAPN8 LMO7 SEL1L3 PLCL1 DNAH5

2.60e-061981367af399569c718f5fd971d73a7926768c9311002a3
ToppCellLPS_only-Hematopoietic_Erythro-Megakary|LPS_only / Treatment groups by lineage, cell group, cell type

SPTA1 PRXL2A NEK2 TESC SULT4A1 TOP1 SLC16A10

2.78e-062001367ce8281c9556a1f64f8ca8a029110077d4ef5b35e
ToppCellBiopsy_IPF-Epithelial|Biopsy_IPF / Sample group, Lineage and Cell type

MAP9 PLEKHS1 DNAH12 LMO7 DNAH5 DNAH6 DNAH11

2.78e-06200136776f1ac00b34d07057d8da03d276438b719b46b1d
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|LPS_only / Treatment groups by lineage, cell group, cell type

SPTA1 PRXL2A NEK2 TESC SULT4A1 TOP1 SLC16A10

2.78e-06200136783c4181c083b364f0d3a89ae7a0504781fa9fa9f
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_only / Treatment groups by lineage, cell group, cell type

SPTA1 PRXL2A NEK2 TESC SULT4A1 TOP1 SLC16A10

2.78e-062001367f15baf287ec467664c23faa53fdea45257f7b9d0
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

PLEKHS1 DNAH12 LMO7 DNAH5 DNAH6 DNAH11

7.10e-0615113668216462e723fec2797387929dde095370947e10a
ToppCellsevere-CD4+_T_naive|severe / disease stage, cell group and cell class

HYKK POLH LMO7 LRP6 PLCL1 SLC16A10

1.26e-05167136602a8215fca59c357c1cdaa5738849eacf98c0bcc
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 SPTA1 TEP1 ABCA9 JMY NAV1

1.35e-0516913665f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTA1 ATP13A5 NGF DNAH5 DNAH6 DNAH11

1.35e-05169136612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

CAPN12 FMO5 USP9Y LMO7 PLCL1 DNAH5

1.70e-0517613663fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

WSB1 CASZ1 CAPN8 SLC9A2 SEL1L3 DNAH5

1.70e-0517613663bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHS1 DNAH12 PNMA8A DNAH5 DNAH6 FBXO15

1.75e-051771366aef050784abbba45c4ab4e8328339c8739c5c453
ToppCellHealthy_Control-Lymphoid-NK-NK|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CAPN12 CCDC141 SLC38A1 MLC1 SPON2 TESC

1.81e-05178136671e99f143009b2d29cb47b96393b58b514c8cfc6
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

NEK2 DNAH12 DNAH17 DNAH5 DNAH6 DNAH11

1.81e-051781366d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

ABCC5 PLEKHS1 ATP13A5 CAPN8 PALM3 PLCL1

1.81e-05178136635a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

C10orf67 DNAH12 DNAH5 DNAH6 FBXO15 DNAH11

2.25e-0518513665e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

C10orf67 DNAH12 DNAH5 DNAH6 FBXO15 DNAH11

2.25e-0518513663e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 USP13 CCDC141 FABP3 ALPK3 TESC

2.46e-0518813664db566f3f708e66730aa9e16f4d73d91dc534177
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

ABCC5 ABCA9 CASZ1 ALPK3 PLCB4 TESC

2.46e-051881366df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 USP13 CCDC141 FABP3 ALPK3 TESC

2.46e-0518813666704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHS1 DNAH12 DNAH5 DNAH6 FBXO15 DNAH11

2.54e-051891366a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellAdult|World / Lineage, Cell type, age group and donor

CAPN12 MRC1 CASZ1 CAPN8 DNAH5 SLC16A10

2.54e-0518913665cd285bfad973125d46d704fec18b21266a63379
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

PLEKHS1 DNAH12 DNAH5 DNAH6 FBXO15 DNAH11

2.54e-05189136627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 ESRP2 NEK2 LMO7 SEL1L3 PLCB4

2.54e-051891366c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellCiliated|World / shred by cell class for parenchyma

PLEKHS1 DNAH12 DNAH5 DNAH6 FBXO15 DNAH11

2.54e-051891366711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

ABCC5 PLEKHS1 CAPN8 SEL1L3 PLCL1 DNAH5

2.61e-051901366756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC5 CAPN8 LMO7 SEL1L3 PLCL1 DNAH5

2.69e-05191136623776c7302cead3881b39127398f3b3e0d27885e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFT27 MAP9 PLEKHS1 DNAH12 DNAH5 DNAH6

2.77e-05192136603acd4a26b986e34eee608747347791122f1aa52
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFT27 MAP9 PLEKHS1 DNAH12 DNAH5 DNAH6

2.77e-05192136631c6046589e2fbb0486fd044c5b128099d37872f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA2 ACTN4 B4GALT6 MLC1 SPON2 TESC

2.85e-051931366b53ffef20f918b7d1e9d3924562691d13245e2dd
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

IFT27 PLEKHS1 DNAH12 DNAH5 DNAH6 DNAH11

2.85e-051931366a0baa8be6f590b2031fede22be588715ae458e93
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC38A1 DNAH12 TAGLN3 RAB40AL LRP6 CACYBP

2.85e-051931366088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PLEKHS1 DNAH12 DNAH5 DNAH6 FBXO15 DNAH11

2.94e-051941366756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WSB1 CAPN8 LMO7 SEL1L3 PALM3 PLCL1

2.94e-0519413665b29c843186c2394f5bec3b1d5ae284a0d931d85
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WEE1 MIER1 LMO7 PLCB4 UTRN TOP1

2.94e-051941366e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WSB1 CAPN8 LMO7 SEL1L3 PALM3 PLCL1

2.94e-051941366ebcf6c6d0eb20a5d422becf5a730089230c8ba9a
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WSB1 CAPN8 LMO7 SEL1L3 PALM3 PLCL1

2.94e-0519413668c6e5ba27a988e0cd6b8c25cb9a30a0da2b1f7f9
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WSB1 CAPN8 LMO7 SEL1L3 PALM3 PLCL1

2.94e-0519413666e78e3046c5b172af92a84e25f982377a0aaac58
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA2 ACTN4 SLC38A1 MLC1 SPON2 UTRN

2.94e-051941366ae5357e2a276473cde1fc8c43acaf9f69da35fd7
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA2 ACTN4 SLC38A1 MLC1 SPON2 UTRN

2.94e-0519413663a0b8b5d0354c43da57bb951cd8ba878363c3de5
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

USP13 CCDC141 CASZ1 LMO7 ALPK3 PLCL1

3.02e-051951366f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

PLEKHS1 DNAH12 PLCB4 DNAH5 DNAH6 DNAH11

3.02e-05195136621dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

USP13 CCDC141 CASZ1 LMO7 ALPK3 PLCL1

3.02e-05195136675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellnormal_Lymph_Node-T/NK_cells-NK|normal_Lymph_Node / Location, Cell class and cell subclass

CAPN12 ABCA2 ACTN4 B4GALT6 MLC1 SPON2

3.11e-05196136600ab4a1547752d419aa720b39b94a4ab2ede963a
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

CAPN12 WSB1 FMO5 CAPN8 LMO7 LRP6

3.11e-051961366754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH12 LMO7 PLCB4 DNAH5 DNAH6 DNAH11

3.11e-051961366af4cdc61830685a888a1209826c23bcf54a43084
ToppCell(08)_PNEC|World / shred by cell type and Timepoint

DPYSL2 B4GALT6 PNMA8B NGF SULT4A1 PGBD5

3.11e-0519613662ee37155c03cd5009427a4bffe6c80ed2ac6939e
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH12 LMO7 PLCB4 DNAH5 DNAH6 DNAH11

3.11e-0519613666d02d494196e3f857d53eea46d9419690d43beca
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

PLEKHS1 DNAH12 LMO7 DNAH5 DNAH6 DNAH11

3.11e-05196136687d9881cfec461a5d89b688a83749b618c519485
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WSB1 MRC1 USP13 DPYSL2 GLDN CCDC141

3.11e-051961366006d783a530aa6e1e6545dcc2e6b00bb300fe070
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

IFT27 PLEKHS1 DNAH12 LMO7 DNAH5 DNAH11

3.20e-051971366272c7f4e582ef57564450540242b0db766b78328
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

PLEKHS1 DNAH12 LMO7 DNAH5 DNAH6 DNAH11

3.20e-05197136618fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ZMYND15 MRC1 ABCC5 FABP3 ADAMDEC1 PGBD5

3.20e-051971366075044c17f1c52008cd3c292c15cbf485b50411e
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC5 CAPN8 LMO7 SEL1L3 PLCL1 DNAH5

3.29e-0519813661408e02e053ad3406229bfe8189da03be6366e81
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLEKHS1 CAPN8 LMO7 SEL1L3 PLCL1 DNAH5

3.29e-0519813666ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WSB1 USP13 FMO5 CCDC141 CAPN8 LRP6

3.39e-0519913662dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPD1 MRC1 GLDN GPR19 RNASEH2A SPTA1

3.39e-051991366e1190b1c2d21fed313bb58e24d0e6365de6e6599
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-Neurons|GW19 / Sample Type, Dataset, Time_group, and Cell type.

WSB1 DPYSL2 BZW2 SLC38A1 MTMR6 TAGLN3

3.48e-052001366b9538eb33ac86384e7e289a5a82fac4d56a7b9c2
ToppCellwk_08-11-Epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 ESRP2 LMO7 SEL1L3 TESC UTRN

3.48e-052001366445fc7995ffc440c6256a6aab0bbf33fb0fea028
ToppCellTracheal-10x3prime_v2-Epithelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRXL2A PLEKHS1 DNAH12 LMO7 DNAH5 DNAH11

3.48e-052001366e1da1b15d2ca06796ee1ab7cef586ae0b4dc0a0a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal|6m / Sample Type, Dataset, Time_group, and Cell type.

CCDC141 FABP3 DNAH12 LMO7 DNAH11 SLC16A10

3.48e-05200136613ec8afea86e4a10599c924871ba4e325b0a8013
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

GLDN CYP21A2 PRXL2A USP9Y LMO7 SMYD3

3.48e-0520013662d167b6e3f4b47e537b2e5b9b2f104f80573970b
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Nefm_(Deep_layer_pyramidal_cells--layer_5)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

C10orf67 LIPC PALM3 FBXO15

6.27e-057013643fe560cd34a8f264f33dca1479950a60d10a16d9
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l32|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPD1 PNLIPRP1 POLH PRXL2A

1.01e-0479136411e92ae55dae24b6f73dd5a52e1c3c4e579ddf7b
ToppCell368C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AAGAB RAB40AL PALM3 TESC NEURL4

1.10e-041541365f29316d4b4dcdb23bd427d78068e65a9802f7f07
ToppCell368C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AAGAB RAB40AL PALM3 TESC NEURL4

1.10e-04154136566065c0763c83d98084ca6969694c3af37e43274
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MRC1 DPYSL2 PNMA8B NAV1 PLCB3

1.21e-041571365e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ZHX3 USP13 DNAH12 DNAH6 DNAH11

1.21e-041571365410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTA1 PRXL2A ADAMDEC1 PRRG3 SLC16A10

1.25e-0415813659fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MRC1 DPYSL2 PNMA8B NAV1 PLCB3

1.25e-041581365e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTA1 PRXL2A ADAMDEC1 PRRG3 SLC16A10

1.25e-0415813650edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Lypd1_(CA1_Principal_cells_(Anterior))|Hippocampus / BrainAtlas - Mouse McCarroll V32

CYP21A2 SLC9A2 LIPC CDC40

1.28e-0484136452d167614afa9b056f2934142d3250fe5e70e806
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSMB8 CCR1 DNAH5 DNAH6 CAPN15

1.28e-041591365f7803f7b4e0379ae8256ec53110833bedee7db98
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSMB8 CCR1 DNAH5 DNAH6 CAPN15

1.28e-0415913656e2d38e78d2ef7803e8bb154b5c788bf62a41045
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 GPD1 MRC1 FIGNL2 ABCA9

1.32e-0416013650544bc465af208da448858d6e174ff56f2e08a46
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

MRC1 IFT27 ABCC5 ALPK3 PGBD5

1.40e-0416213652f19539c455d1e5d514725845234c7547020e6ad
ToppCellfacs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 MRC1 SPTA1 PRXL2A SLC16A10

1.53e-0416513654f95c2fe5ab4416c736fe0d1936695a2b26777eb
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 TEP1 ABCA9 B4GALT6 CCR1

1.53e-0416513652477b0f1a0ea26184cf3cc4a9ffcdfa825cbc615
ToppCellfacs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 MRC1 SPTA1 PRXL2A SLC16A10

1.53e-0416513653e913b49a868fdd5589200ae3e9be77c0938ba14
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 DNAJC27 B4GALT6 SLC38A1 PLCL1

1.57e-041661365de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN12 LIPC ALDH1L2 PALM3 CCDC9

1.66e-04168136541da200bbff5c663c39f67c38d6d5f43b0ad9494
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN12 LIPC ALDH1L2 PALM3 CCDC9

1.66e-041681365a77259c13508f19186d7b0f80b34dc6d89497ab5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

USP13 WEE1 POLH PBK NEK2

1.71e-041691365b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZMYND15 MRC1 ABCA9 B4GALT6 CCR1

1.85e-041721365f0e767a20d93e546ce278db67dbd779cc68af533
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLHL38 DNAH12 DNAH5 DNAH6 DNAH11

1.90e-041731365c3762655caa79ac4879876f470d32578a3c93b01
ToppCelldroplet-Marrow-nan-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 WDR7 TEP1 DNAH17 NAV1

1.90e-0417313656d2ceba4f89a228600e2b40aba81bb0eb81578c0
ToppCelldroplet-Lung-nan-21m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 MRC1 ABCA9 B4GALT6 DNAH17

1.90e-04173136531ea04e65876c42b90245d280f0b6439bfffbace
ToppCelldroplet-Lung-nan-21m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 MRC1 ABCA9 B4GALT6 DNAH17

1.90e-0417313651cff815536f620e32b9805666e1aa711462c2d25
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP13 RNASEH2A NEK2 DNAH12 PNMA8A

1.95e-0417413650227fea1678baa9168bd47c3b4aacb2592bb5867
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP13 RNASEH2A NEK2 DNAH12 PNMA8A

1.95e-041741365c2f8c59fca5f1ff6ffa6dc8cfce62da4b19fe9b3
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CAPN12 STUB1 CAPN8 UTRN

1.96e-05361314DOID:11723 (implicated_via_orthology)
Diseaselevel of spondin-2 in blood serum

PDE6B SPON2

5.85e-0531312OBA_2043641
DiseaseSeizures, Focal

ACAT1 POLG MLC1 NGF DYNC1H1

1.03e-041041315C0751495
Diseasegalectin-4 measurement

CAPN12 ACTN4

1.17e-0441312EFO_0020398
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAH11

1.17e-0441312DOID:0050144 (is_implicated_in)
DiseaseHMG CoA reductase inhibitor use measurement

ZHX3 STAG1 SLC38A1 LIPC TOP1 DNAH11

2.05e-041891316EFO_0009932
Diseaselung carcinoma (is_implicated_in)

STRAP MAP2K7

4.05e-0471312DOID:3905 (is_implicated_in)
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

ZHX3 SLC38A1 LIPC PLCB3 TOP1 DNAH11

4.09e-042151316EFO_0008317, EFO_0008591
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

ZMYND15 ZHX3 SLC38A1 LIPC PLCB3

8.92e-041661315EFO_0004530, EFO_0004611
Diseasehereditary spastic paraplegia (implicated_via_orthology)

CAPN12 ATP13A5 CAPN8

9.27e-04431313DOID:2476 (implicated_via_orthology)
Diseasevery low density lipoprotein cholesterol measurement

ZHX3 SLC38A1 LIPC PLCB3 TOP1 DNAH11

1.10e-032601316EFO_0008317
DiseaseTonic - clonic seizures

ACAT1 POLG MLC1 NGF

1.21e-031041314C0494475
DiseaseKartagener syndrome (implicated_via_orthology)

DNAH5 DNAH11

1.72e-03141312DOID:0050144 (implicated_via_orthology)
Diseasetriglycerides in medium HDL measurement

STAG1 SLC38A1 LIPC

1.80e-03541313EFO_0022321
Diseasered blood cell density measurement

SPTA1 CYP21A2 CASZ1 LIPC PHF20L1 TBC1D12 NGF PALM3 PLCB3 TOP1 SLC16A10

1.93e-0388013111EFO_0007978
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

STAG1 JMY SLC38A1 LIPC PLCB3

2.31e-032061315EFO_0004612, EFO_0020947
Diseasetriglycerides to total lipids in small LDL percentage

SLC38A1 LIPC PLCB3

2.32e-03591313EFO_0022337
Diseasecholesteryl esters to total lipids in large HDL percentage

SLC38A1 LIPC PLCB3

2.32e-03591313EFO_0022248
Diseasepolyunsaturated fatty acid measurement

SLC38A1 LIPC TOP1 DNAH11

2.81e-031311314EFO_0010733
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

ZHX3 SLC38A1 LIPC PLCB3 DNAH11

3.06e-032201315EFO_0004529, EFO_0008317
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

STAG1 SLC38A1 LIPC PLCB3 TOP1

3.37e-032251315EFO_0008317, EFO_0020947
DiseaseBenign Neoplasm

PLEKHS1 YY1 TOP1

3.47e-03681313C0086692
DiseaseNeoplasms

PLEKHS1 YY1 TOP1

3.47e-03681313C0027651
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

ZHX3 SLC38A1 LIPC PLCB3 DNAH11

3.63e-032291315EFO_0004639, EFO_0008317
Diseasebilirubin measurement

ZHX3 STAG1 SPTA1 CYP21A2 BCO1 TOP1 DNAH11

3.67e-034421317EFO_0004570
DiseaseBronchiectasis

DNAH5 DNAH11

4.26e-03221312C0006267
DiseaseDown syndrome (is_marker_for)

FABP3 ACTR1A

4.26e-03221312DOID:14250 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
WTQVFASVMKDIKEG

TBC1D12

751

O60347
GIAASFAVKLFKAWM

BZW2

181

Q9Y6E2
KMFEGTAWKMEDCIV

ATP13A5

551

Q4VNC0
MEVEKAFGSTNVLWK

LINC00696

81

Q6ZRV3
ASGAKKRFWIIEDMS

CASZ1

1396

Q86V15
MKCEGSEFWEKGFVA

ABCA9

166

Q8IUA7
IMGDKKAGFSVFWAD

ALDH1L2

146

Q3SY69
KKMIAASWVFDAGFV

GPR19

181

Q15760
MWVSKKEYEEDGSRA

ACTR1B

356

P42025
KASIHEAWTDGKEAM

ACTN4

421

O43707
AGVDWKMTDVQIATK

ALPK3

1776

Q96L96
RSWKAAKVFMGKVDD

DNAH11

3236

Q96DT5
WVTEHFSGIMVKEFK

GLDN

336

Q6ZMI3
DKKVEDGEFWMSLSD

CAPN8

316

A6NHC0
WKLEAESMGFFTKEE

DCUN1D5

91

Q9BTE7
SFEGMDRWIKKIEEH

RAB40A

101

Q8WXH6
SFEGMDRWIKKIEEH

RAB40AL

101

P0C0E4
MKEDGWVKVESTDVS

PSMB8

251

P28062
WEAEKRKAEESMGIG

PALM3

391

A6NDB9
DLIWAKMLSSKEAGF

CAPN15

676

O75808
VSHKADVDMVDKSGW

ANKFY1

276

Q9P2R3
EFEEMAAWALAAGRK

PNMA8A

181

Q86V59
EFKAVKDWEILLAFM

DPY19L2P1

226

Q6NXN4
KNDEFISFVGTWMKL

nan

1236

O00370
MEWGEDIKAVSKDEA

LPGAT1

81

Q92604
REEALASFEAWKAMK

MAP9

466

Q49MG5
GKASWAAAAERMEKL

JMY

466

Q8N9B5
TFVKALTMDGKQAAW

NGF

206

P01138
WKELDYGSMTEAEKQ

NEK2

36

P51955
EVDQSGEWFKEGMKL

MBTD1

376

Q05BQ5
MAAPTKKELEAAWGV

GTPBP6

181

O43824
IKGFMVLIEKDWISF

MTMR6

361

Q9Y217
KDSFDALDAWLAEMK

DNAJC27

101

Q9NZQ0
WDKAVVTGKMDENQF

DPYSL2

366

Q16555
DDAMAADKSDEWFAK

GLOD4

291

Q9HC38
DEHWAMKAIETFSGK

IGF2BP1

46

Q9NZI8
TIEEAMVKKWADFAG

CYP21A2

76

P08686
MDKKFGSSWHVVIGE

DNAL4

61

O96015
MVDAFLGTWKLVDSK

FABP3

1

P05413
FIDKGDESWVTDMCK

PNLIPRP1

96

P54315
LEVDVASWFKDVMAK

MAP2K7

386

O14733
GLLDMTKEKEFFDVW

PDE6B

276

P35913
TKEKEFFDVWSVLMG

PDE6B

281

P35913
DGDDDMKRTINKAWV

CACYBP

201

Q9HB71
WAEFEAMAAIFKIAT

MAP3K2

561

Q9Y2U5
IAAKMIKAAIEEGTW

DNAH12

2536

Q6ZR08
ERAWKGGTESEMFNK

POLG

1046

P54098
GELIMIKFKWENSAV

LIPC

411

P11150
SKEWEEAMAKAQETG

LMO7

1101

Q8WWI1
WGDAKTDKIEVMNTD

LRP6

506

O75581
MWVIGLVFKKTENSE

PAPOLA

436

P51003
DGAWVEVTLTEMKAF

PGBD5

156

Q8N414
DTAKVWSEELFKLAM

PLCB3

126

Q01970
VAHKKGELSMEDVWS

ABCC5

121

O15440
MNGKVWDLFPEADKV

EIF3C

761

Q99613
ALLVKKEDGEFWMEL

CAPN12

311

Q6ZSI9
AEAKMFLQVDKSWKE

DNAH6

1126

Q9C0G6
NVEEWLGKVEEAMFT

DNAH6

1276

Q9C0G6
AGKELFSEMLDKLWE

IFT27

66

Q9BW83
MGQKAVEEIWFETAK

HYKK

351

A2RU49
MVNSGEAAAKEEWVA

CABIN1

771

Q9Y6J0
MWEEEFTFELNAKSK

C2CD2

311

Q9Y426
EEDSMKWRAKAEEYG

CCDC141

876

Q6ZP82
GFKEAMKDSVWDCVI

B4GALT6

211

Q9UBX8
RSLDKEMKTWDAFVG

DNAH17

1321

Q9UFH2
IDYKLKDDWVFGDAM

CCR1

91

P32246
GVWKKEEELAFVMAN

FBXO15

301

Q8NCQ5
REWDAEKTDGMFKDG

CCDC9

291

Q9Y3X0
MKEVIDAFISENGWV

STUB1

286

Q9UNE7
WEVVTESEGKKEMNV

FMO5

126

P49326
TEEFNGSDWEKAMKE

CENPV

251

Q7Z7K6
GWIQFMSKVSVDIFK

ABCA2

566

Q9BZC7
MWVSKKEYEEDGARS

ACTR1A

356

P61163
VTMWVFEEDIGGKKL

GPD1

36

P21695
SFSWLEEMGVQDKIK

DONSON

361

Q9NYP3
MEAVKAEAWEGAAVA

FAM98C

1

Q17RN3
LDVSKEGTEAWEAAM

DYNC1H1

536

Q14204
KVMKLNFEAAWDEVG

COPG1

766

Q9Y678
AKELDSFVEWDKMYG

FIGNL2

636

A6NMB9
DMEAWKDVTSGNAKI

OLAH

216

Q9NV23
LDKVSWEEVKNEMVG

HARS1

241

P12081
FQVRIDKMVDKWAGS

NEURL4

566

Q96JN8
DKMVDKWAGSIEIGV

NEURL4

571

Q96JN8
DLKFALTAETKAWMV

DNAH5

1201

Q8TE73
EDWKKEIMVGSMFQA

MIER1

176

Q8N108
FKDLNVGIIDAWDMT

NXPE1

506

Q8N323
MGSEDWIALVKAAAA

PHF20L1

166

A8MW92
ISLDKKFAWMDGSKV

MRC1

866

P22897
GKVDWKMLDEAVFQV

NAV1

1451

Q8NEY1
FEADSTVIEKWMDGV

UTRN

1021

P46939
LKVQTKEDGDVFMWL

SEL1L3

666

Q68CR1
KEDGDVFMWLKHEAT

SEL1L3

671

Q68CR1
DFAERGEAWALMKEI

SPON2

96

Q9BUD6
KKGLVTVEDEQAWMA

PLCB4

536

Q15147
AKMEDTDFVGWALDV

RNASEH2A

81

O75792
DKDMKGFSWAIVPAL

TMEM225B

6

P0DP42
FQTVDLWEGKDMAAV

TAGLN3

111

Q9UI15
AEVMKEEKENAWEGG

PNMA8B

461

Q9ULN7
FVAGMSDKKIVQWDI

CDC40

391

O60508
MGWTSEKAEVEKIIA

SLC9B2

376

Q86UD5
EGAAVFWNVKDKTMK

RMND1

231

Q9NWS8
GLKKEDIAMWEVNEA

ACAT1

341

P24752
AFGVTRSMWADDAKK

POLH

56

Q9Y253
DDFGVWEVKTMVAVI

ESRP2

196

Q9H6T0
AKELWEKNGAVIMAV

PRXL2A

66

Q9BRX8
KDADMLTGDEQVWKE

SMYD3

271

Q9H7B4
FTAKVWDAVSGDELM

STRAP

81

Q9Y3F4
VHAEKVAKAFWMAIG

AAGAB

286

Q6PD74
VGMEIWSDGDKIKVV

ADAMDEC1

266

O15204
LFITDMDWDTKKQAA

BCO1

516

Q9HAY6
DFLKIWQGIDIETKM

TESC

186

Q96BS2
TFGTRWEAMKAKATE

C10orf67

31

Q8IYJ2
GHDREKIKDWVSFMS

PLEKHS1

111

Q5SXH7
FMWLKTVFEAADVDG

PLCL1

241

Q15111
GDAKTFWMELEDDGK

SETDB2

6

Q96T68
EGDEDDWASNKVMFK

WEE1

446

P30291
VKKLDADWVEGYSME

GGCX

216

P38435
RWFDSEEKKGAETQM

TEP1

191

Q99973
GLWKDIFTVSMNEKF

SULT4A1

251

Q9BR01
SYKMEWKNEVDVDSG

SLC9A2

726

Q9UBY0
EGEFSVTMWSSDEKK

YY1

216

P25490
VKLGKSAMQSVVDDW

STAG1

91

Q8WVM7
DADDLGKWIMEKVNI

SPTA1

61

P02549
DKADIFAFGLTLWEM

PBK

226

Q96KB5
KILMDEAVSGWKFEI

USP9Y

131

O00507
VIVSASSDGFIKMWK

PAK1IP1

261

Q9NWT1
IFMKGNTIKETEAWD

NSMCE3

186

Q96MG7
SVGASKAVFLWNMDK

WSB1

231

Q9Y6I7
QWFAEKMGEETRAVA

ZHX3

881

Q9H4I2
DFSVIIWDIFSGEMK

WDR7

491

Q9Y4E6
EAGKEFDLVMVFWEL

ZMYND15

516

Q9H091
KTQREKFAWAIDMAD

TOP1

746

P11387
VKEVFENKEKTMEFW

PRRG3

46

Q9BZD7
TKWSLLMEDIFGKET

ZNF317

136

Q96PQ6
AIKFLMGKEETFSAW

SLC38A1

176

Q9H2H9
GLDWVPKKFDVSIDM

USP13

591

Q92995
EVLTSKGDAWAKYMA

TRIR

141

Q9BQ61
DFSLGEWKTQMEETK

THPO

66

P40225
GEEEKVFEALMVWIK

KLHL38

191

Q2WGJ6
DDDKMVFKTAWVGSL

SLC16A10

106

Q8TF71
EFDKEKAWRAVVVQM

MLC1

361

Q15049