Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	TBP_eukaryotic	TBPL2 TBP	4.37e-05	2	124	2	IPR033710
Domain	TRPV5/TRPV6	TRPV6 TRPV5	4.37e-05	2	124	2	IPR008344
Domain	TBP_CS	TBPL2 TBP	4.37e-05	2	124	2	IPR030491
Domain	TRP_channel	TRPC1 TRPV6 TRPV5	4.53e-05	11	124	3	IPR004729
Domain	TFIID	TBPL2 TBP	1.31e-04	3	124	2	PS00351
Domain	TBP	TBPL2 TBP	1.31e-04	3	124	2	IPR000814
Domain	TBP	TBPL2 TBP	1.31e-04	3	124	2	PF00352
Domain	AAA	DNAH3 DNAH10 LONP2 VPS4B MCM7 HELZ2	4.01e-04	144	124	6	SM00382
Domain	AAA+_ATPase	DNAH3 DNAH10 LONP2 VPS4B MCM7 HELZ2	4.01e-04	144	124	6	IPR003593
Domain	Beta2_adaptin/TBP_C_dom	TBPL2 TBP	6.45e-04	6	124	2	IPR012295
Domain	-	TBPL2 TBP	6.45e-04	6	124	2	3.30.310.10
Domain	ZF_A20	OTUD7A RABGEF1	8.98e-04	7	124	2	PS51036
Domain	zf-A20	OTUD7A RABGEF1	8.98e-04	7	124	2	PF01754
Domain	Znf_A20	OTUD7A RABGEF1	8.98e-04	7	124	2	IPR002653
Domain	ZnF_A20	OTUD7A RABGEF1	8.98e-04	7	124	2	SM00259
Domain	NHL_repeat	NHLRC2 LRP1B	1.90e-03	10	124	2	IPR001258
Domain	NHL	NHLRC2 LRP1B	1.90e-03	10	124	2	PF01436
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH10	3.78e-03	14	124	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH10	3.78e-03	14	124	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH10	3.78e-03	14	124	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH10	3.78e-03	14	124	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH10	3.78e-03	14	124	2	IPR011704
Domain	MT	DNAH3 DNAH10	3.78e-03	14	124	2	PF12777
Domain	AAA_8	DNAH3 DNAH10	3.78e-03	14	124	2	PF12780
Domain	AAA_5	DNAH3 DNAH10	3.78e-03	14	124	2	PF07728
Domain	P-loop_NTPase	MPP2 WSCD1 DNAH3 DNAH10 LONP2 MYO9B KIF21A VPS4B MCM7 N4BP2 HELZ2 HFM1 MX2	4.18e-03	848	124	13	IPR027417
Domain	DHC_fam	DNAH3 DNAH10	4.34e-03	15	124	2	IPR026983
Domain	Dynein_heavy	DNAH3 DNAH10	4.34e-03	15	124	2	PF03028
Domain	Dynein_heavy_dom	DNAH3 DNAH10	4.34e-03	15	124	2	IPR004273
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	KIF21A MCM7 SCLY NHLRC2 RPS28 CHRAC1 DPP8 WNK1 UBA1 EHBP1L1 PPP3CB LMNA TSR1 FANCI ARHGEF1 RABGEF1 PLEC QARS1 ALDOC AHNAK2 KPNB1	6.30e-08	1455	126	21	22863883
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TCF20 COPG2 HEATR1 NDUFS1 HP1BP3 WDR3 LMNA TSR1 FANCI HELZ2 PLEC SPEN NNT KPNB1	1.18e-07	653	126	14	22586326
Pubmed	Defining the membrane proteome of NK cells.	DIP2B LONP2 MYO9B PIGS MCM7 HEATR1 LTB4R2 SLC4A2 EHBP1L1 INTS2 FANCI IER3IP1 HELZ2 LRRC8A KDSR NNT KPNB1	1.16e-06	1168	126	17	19946888
Pubmed	Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.	CNNM2 TRPV6 TRPV5	2.57e-06	8	126	3	33859252
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	MYO9B MCM7 FAM131A FAT1 LMNA HELZ2 PLEC AHNAK2 KPNB1	3.66e-06	332	126	9	37433992
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	DIP2B WNK1 UBA1 HELZ2 C3 PLEC ALDOC NNT KPNB1	4.87e-06	344	126	9	30333137
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	MYO9B MCM7 HEATR1 FAT1 PELO FANCI	5.23e-06	120	126	6	27320910
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	SNX3 ACACB COPG2 MCM7 HEATR1 RPS28 NDUFS1 HP1BP3 WDR3 PELO LMNA RBM27 TSR1 ARHGEF1 PLEC QARS1 KPNB1	5.80e-06	1318	126	17	30463901
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	DNAH3 COPG2 MCM7 RPS28 NDUFS1 HP1BP3 UBA1 LMNA HELZ2 PLEC QARS1 MX2 KPNB1	7.48e-06	803	126	13	36517590
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	TCF20 MYO9B KIF21A MCM7 HEATR1 NDUFS1 WDR3 UBA1 KANSL1 PELO LMNA FANCI ARHGEF1 PLEC QARS1 AHNAK2 KPNB1	8.17e-06	1353	126	17	29467282
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MPP2 DIP2B TCF20 KIF21A SHANK3 FRY UBA1 PPP3CB GPR158 TMEM259 PTPRS N4BP2 RABGEF1 KPNB1	1.11e-05	963	126	14	28671696
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	MYO9B COPG2 MCM7 NDUFS1 PELO LMNA KPNB1	1.26e-05	211	126	7	17314511
Pubmed	Alteration of calcium homeostasis in primary preeclamptic syncytiotrophoblasts: effect on calcium exchange in placenta.	TRPV6 TRPV5	1.30e-05	2	126	2	20178461
Pubmed	The TRPV5/6 calcium channels contain multiple calmodulin binding sites with differential binding properties.	TRPV6 TRPV5	1.30e-05	2	126	2	22354706
Pubmed	Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane.	TRPV6 TRPV5	1.30e-05	2	126	2	16564089
Pubmed	Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells.	TRPV6 TRPV5	1.30e-05	2	126	2	19295174
Pubmed	Human TRPV5 and TRPV6: key players in cadmium and zinc toxicity.	TRPV6 TRPV5	1.30e-05	2	126	2	23968883
Pubmed	Expression of calcium channels along the differentiation of cultured trophoblast cells from human term placenta.	TRPV6 TRPV5	1.30e-05	2	126	2	12390878
Pubmed	TRPV5 and TRPV6 are expressed in placenta and bone tissues during pregnancy in mice.	TRPV6 TRPV5	1.30e-05	2	126	2	30916584
Pubmed	Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4.	TRPV6 TRPV5	1.30e-05	2	126	2	16565876
Pubmed	Age-dependent alterations in Ca2+ homeostasis: role of TRPV5 and TRPV6.	TRPV6 TRPV5	1.30e-05	2	126	2	16705151
Pubmed	Expression of protein-tyrosine phosphatases in the major insulin target tissues.	PTPRA PTPRS	1.30e-05	2	126	2	9357975
Pubmed	Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium.	TRPV6 TRPV5	1.30e-05	2	126	2	20405023
Pubmed	A single amino acid mutation results in a rapid inactivation of epithelial calcium channels.	TRPV6 TRPV5	1.30e-05	2	126	2	11846401
Pubmed	Expression and prognostic roles of TRPV5 and TRPV6 in non-small cell lung cancer after curative resection.	TRPV6 TRPV5	1.30e-05	2	126	2	24761864
Pubmed	Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.	TRPV6 TRPV5	1.30e-05	2	126	2	12077127
Pubmed	[The functional characteristics oF TRPV5 and TRPV6 channels in normal and transformed human blood lymphocytes].	TRPV6 TRPV5	1.30e-05	2	126	2	24592736
Pubmed	Hepatic nuclear factor 4α positively regulates complement C3 expression and does not interfere with TNFα-mediated stimulation of C3 expression in HepG2 cells.	HNF4A C3	1.30e-05	2	126	2	23628799
Pubmed	HNF4 alpha and the Ca-channel TRPC1 are novel disease candidate genes in diabetic nephropathy.	TRPC1 HNF4A	1.30e-05	2	126	2	18184923
Pubmed	Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.	TRPV6 TRPV5	1.30e-05	2	126	2	12574114
Pubmed	Structural conservation of the genes encoding CaT1, CaT2, and related cation channels.	TRPV6 TRPV5	1.30e-05	2	126	2	11549322
Pubmed	[TRPV5 and TRPV6 calcium channels in human T cells].	TRPV6 TRPV5	1.30e-05	2	126	2	19140341
Pubmed	Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID.	HNF4A TBP	1.30e-05	2	126	2	19805548
Pubmed	Inhibition of the calcineurin-NFAT signalling cascade in the treatment of heart failure.	PPP3CB KPNB1	1.30e-05	2	126	2	19925438
Pubmed	First evidence of TRPV5 and TRPV6 channels in human parathyroid glands: possible involvement in neoplastic transformation.	TRPV6 TRPV5	1.30e-05	2	126	2	25164318
Pubmed	Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.	TRPV6 TRPV5	1.30e-05	2	126	2	15123711
Pubmed	Single-channel activities of the human epithelial Ca2+ transport proteins CaT1 and CaT2.	TRPV6 TRPV5	1.30e-05	2	126	2	11719848
Pubmed	Concerted action of associated proteins in the regulation of TRPV5 and TRPV6.	TRPV6 TRPV5	1.30e-05	2	126	2	17233615
Pubmed	Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.	TRPC1 TRPV6	1.30e-05	2	126	2	22932896
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MCM7 HEATR1 HP1BP3 WDR3 UBA1 PPP3CB LMNA RBM27 TSR1 HELZ2 LRRC8A C3 PLEC QARS1 SPEN KPNB1	1.32e-05	1257	126	16	36526897
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	TCF20 MCM7 HEATR1 RPS28 WDR3 UBA1 LMNA RBM27 TSR1 FANCI NR0B1 PLEC QARS1 KPNB1	1.49e-05	989	126	14	36424410
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DIP2B SNX3 TCF20 DPP8 WNK1 USP31 SYNJ2 N4BP2 ARHGEF1 OTUD7A RABGEF1 PLEC AHNAK2	1.56e-05	861	126	13	36931259
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	CTU2 PIGS KIF21A RPS28 WNK1 NDUFS1 WDR3 FAT1 UBA1 TSR1 TMEM259 ARHGEF1 C3 QARS1 SDCBP KPNB1	1.93e-05	1297	126	16	33545068
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TCF20 MYO9B MCM7 HEATR1 HP1BP3 WDR3 UBA1 LMNA SLC20A1 PLEC QARS1 SPEN NNT KPNB1	2.18e-05	1024	126	14	24711643
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	COPG2 MCM7 HEATR1 NDUFS1 WDR3 UBA1 LMNA FANCI PLEC QARS1 KPNB1	2.20e-05	638	126	11	33239621
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TCF20 ACACB VPS4B COPG2 MCM7 GREB1L N4BP2 NR0B1 PLEC	2.29e-05	418	126	9	34709266
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	DIP2B TCF20 MYO9B RPS28 PELO TRPV5 SDCBP TBP	2.36e-05	321	126	8	32098917
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	TCF20 PIGS MCM7 HEATR1 HMOX1 HP1BP3 WDR3 LMNA INTS2 RBM27 FANCI PLEC QARS1 NNT KPNB1	3.17e-05	1203	126	15	29180619
Pubmed	Calcium store contents control the expression of TRPC1, TRPC3 and TRPV6 proteins in LNCaP prostate cancer cell line.	TRPC1 TRPV6	3.90e-05	3	126	2	16529812
Pubmed	Molecular cloning and characterization of the human PED/PEA-15 gene promoter reveal antagonistic regulation by hepatocyte nuclear factor 4alpha and chicken ovalbumin upstream promoter transcription factor II.	HNF4A PEA15	3.90e-05	3	126	2	18765665
Pubmed	Kidney injury accelerates cystogenesis via pathways modulated by heme oxygenase and complement.	HMOX1 C3	3.90e-05	3	126	2	22518005
Pubmed	TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells.	TBPL2 TBP	3.90e-05	3	126	2	26880551
Pubmed	Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.	TRPV6 TRPV5	3.90e-05	3	126	2	17200157
Pubmed	The nuclear import of protein kinase D3 requires its catalytic activity.	PRKD3 KPNB1	3.90e-05	3	126	2	16380377
Pubmed	Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner ear.	TRPV6 TRPV5	3.90e-05	3	126	2	19922080
Pubmed	Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.	TRPV6 TRPV5	3.90e-05	3	126	2	16380433
Pubmed	A molecular determinant of phosphoinositide affinity in mammalian TRPV channels.	TRPV6 TRPV5	3.90e-05	3	126	2	27291418
Pubmed	DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression.	HNF4A NR0B1	3.90e-05	3	126	2	19651776
Pubmed	Anchored phosphatases modulate glucose homeostasis.	AKAP5 PPP3CB	3.90e-05	3	126	2	22940692
Pubmed	Prevalence and architecture of de novo mutations in developmental disorders.	TCF20 SPEN	3.90e-05	3	126	2	28135719
Pubmed	Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport.	TRPV6 TRPV5	3.90e-05	3	126	2	16763551
Pubmed	Heme catabolism by tumor-associated macrophages controls metastasis formation.	HMOX1 C3	3.90e-05	3	126	2	33903766
Pubmed	Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane.	TRPV6 TRPV5	3.90e-05	3	126	2	16354700
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DIP2B TCF20 NDUFS1 HP1BP3 EHBP1L1 LMNA RBM27 TSR1 VCAN CFAP45 HELZ2 PLEC SPEN KPNB1	3.97e-05	1082	126	14	38697112
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	COPG2 MCM7 HP1BP3 UBA1 LMNA TSR1 QARS1 NNT KPNB1	4.14e-05	451	126	9	36168627
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	DIP2B SNX3 AKAP5 SLC4A2 FAT1 EHBP1L1 PTPRA PPP3CB GPR158 VPS13B	4.48e-05	569	126	10	30639242
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYO9B CFAP43 WNK1 FAT1 EHBP1L1 KANSL1 TMEM259 PTPRS SLC25A39 FANCI HELZ2 PLEC SPEN AHNAK2	4.98e-05	1105	126	14	35748872
Pubmed	Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions.	ITIH3 SYNJ2 C3 PLEC	5.21e-05	56	126	4	37059927
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	MPP2 KIF21A COPG2 KANSL1 PELO LMNA FANCI ARHGEF1 PLEC KPNB1	5.41e-05	582	126	10	20467437
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	LONP2 KIF21A MCM7 RPS28 WNK1 HP1BP3 UBA1 PELO LMNA TSR1 ARHGEF1 PLEC QARS1 SDCBP AHNAK2 KPNB1	5.47e-05	1415	126	16	28515276
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	SNX3 MCM7 HEATR1 RPS28 NDUFS1 LMNA ARHGEF1 PLEC QARS1 SDCBP KPNB1	5.56e-05	707	126	11	19738201
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DNAH10 TRPC1 MCM7 HEATR1 NDUFS1 WDR3 UBA1 LMNA TSR1 FANCI QARS1 SPEN ALDOC NNT SDCBP KPNB1	5.94e-05	1425	126	16	30948266
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	MYO9B COPG2 MCM7 HEATR1 RPS28 NDUFS1 LMNA PLEC QARS1 ALDOC CPNE7 KPNB1	6.00e-05	844	126	12	25963833
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	RIDA TCF20 VPS4B NHLRC2 HMOX1 WNK1 NDUFS1 SLC4A2 SYNJ2 SLC20A1 N4BP2	7.66e-05	733	126	11	34672954
Pubmed	Co-operation of the transcription factor hepatocyte nuclear factor-4 with Sp1 or Sp3 leads to transcriptional activation of the human haem oxygenase-1 gene promoter in a hepatoma cell line.	HMOX1 HNF4A	7.78e-05	4	126	2	12133007
Pubmed	Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.	DNAH3 DNAH10	7.78e-05	4	126	2	11175280
Pubmed	SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells.	SLC25A40 SLC25A39	7.78e-05	4	126	2	34707288
Pubmed	Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.	TRPV6 TRPV5	7.78e-05	4	126	2	12660155
Pubmed	Lipoxin A4 attenuates hyperoxia‑induced lung epithelial cell injury via the upregulation of heme oxygenase‑1 and inhibition of proinflammatory cytokines.	FPR2 HMOX1	7.78e-05	4	126	2	31746387
Pubmed	Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development.	HNF4A TBP	7.78e-05	4	126	2	16880515
Pubmed	Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.	SNX3 MCM7 HEATR1 RPS28 HP1BP3 LMNA PLEC SDCBP KPNB1	7.93e-05	491	126	9	22623428
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	WNK1 NDUFS1 PRKD3 LMNA XIRP2 RABGEF1 PLEC SDCBP KPNB1	8.69e-05	497	126	9	23414517
Pubmed	SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.	COPG2 MCM7 QARS1 KPNB1	8.82e-05	64	126	4	26511642
Pubmed	Mapping the expression of transient receptor potential channels across murine placental development.	TRPC1 TRPV6 TRPV5	8.89e-05	24	126	3	33884443
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	TCF20 LONP2 ARHGAP10 FAM131A CAMTA2 WNK1 EHBP1L1 LMNA RBM27 TSR1 TMEM259 OTUD7A KPNB1	8.93e-05	1021	126	13	26760575
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	LONP2 ARHGAP10 PIGS MCM7 HEATR1 RPS28 DPP8 WNK1 NDUFS1 UBA1 RABGEF1 C3 PLEC QARS1 KPNB1	9.08e-05	1321	126	15	27173435
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPC1 TRPV6 TRPV5	1.01e-04	25	126	3	16382100
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	LONP2 ARHGAP10 COPG2 HEATR1 RPS28 NDUFS1 GREB1L WDR3 INTS2 SLC25A40 RBM27 TSR1 HELZ2 SPEN SDCBP TBP	1.06e-04	1497	126	16	31527615
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	MCM7 WNK1 LMNA HELZ2 QARS1 AHNAK2 KPNB1	1.12e-04	298	126	7	30737378
Pubmed	A cohesin-RAD21 interactome.	DIP2B MCM7 UBA1 XIRP2 C3 KPNB1	1.16e-04	208	126	6	22145905
Pubmed	Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.	GPR158 TMC5 EPHB1	1.27e-04	27	126	3	18649358
Pubmed	An introduction to TRP channels.	TRPC1 TRPV6 TRPV5	1.27e-04	27	126	3	16460286
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	COPG2 MCM7 NDUFS1 UBA1 LMNA C3 PLEC QARS1 MX2 KPNB1	1.29e-04	647	126	10	26618866
Pubmed	RNA-binding protein SPEN controls hepatocyte maturation via regulating Hnf4α expression during liver development.	HNF4A SPEN	1.29e-04	5	126	2	36577249
Pubmed	Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.	PTPRA PTPRS	1.29e-04	5	126	2	10777529
Pubmed	Role and regulation of TRP channels in neutrophil granulocytes.	TRPV6 TRPV5	1.29e-04	5	126	2	12765698
Pubmed	Calcium transport genes are differently regulated in maternal and fetal placenta in the knockout mice of calbindin-D(9k) and -D(28k).	TRPV6 TRPV5	1.29e-04	5	126	2	22407925
Pubmed	Developmental and cell type-specific regulation of core promoter transcription factors in germ cells of frogs and mice.	TBPL2 TBP	1.29e-04	5	126	2	16412700
Pubmed	Genomic characterization of the lysophosphatidic acid receptor gene, lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA.	MYO9B HMOX1	1.29e-04	5	126	2	10729222
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	PIGS COPG2 HEATR1 RPS28 NDUFS1 INTS2 TMEM259 FANCI QARS1 KPNB1	1.46e-04	657	126	10	36180527
Cytoband	22q13.3	TCF20 SHANK3	1.11e-04	6	126	2	22q13.3
Cytoband	17p13.2	WSCD1 PIGS CAMTA2	4.77e-04	55	126	3	17p13.2
GeneFamily	Transient receptor potential cation channels	TRPC1 TRPV6 TRPV5	2.81e-04	28	83	3	249
GeneFamily	Leukotriene receptors	FPR2 LTB4R2	3.09e-04	6	83	2	204
GeneFamily	CD molecules\|Type II classical cadherins	CDH19 CDH9	1.57e-03	13	83	2	1186
ToppCell	Neuronal_cells-Schwann_cells\|World / Lineage and Cell class	WSCD1 KIF21A LRP1B ITIH3 ALDOC SERPIND1 EPHB1	1.14e-06	189	126	7	371cdc92549269e45c23c5a5b3cae9c5d35ee217
ToppCell	Neuronal_cells\|World / Lineage and Cell class	WSCD1 KIF21A LRP1B ITIH3 ALDOC SERPIND1 EPHB1	1.14e-06	189	126	7	3948775a0ebd4b32c1623d5487f5581e6e2934d7
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.36e-06	194	126	7	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	wk_15-18-Epithelial-Proximal_epithelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.36e-06	194	126	7	b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.41e-06	195	126	7	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.51e-06	197	126	7	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.51e-06	197	126	7	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.51e-06	197	126	7	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.51e-06	197	126	7	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	wk_20-22-Epithelial-Proximal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.56e-06	198	126	7	16c54b884500066ade05a406915f9569ca8abdfc
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.61e-06	199	126	7	b974b495cabbcc3934936cec846c0e2442a70ac3
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CNNM2 ARHGAP10 ITIH3 FAT1 PELO LMNA ALDOC	1.67e-06	200	126	7	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CNNM2 ARHGAP10 CDH19 ITIH3 FAT1 LMNA ALDOC	1.67e-06	200	126	7	c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	TCF20 LRP1B XIRP2 SYNJ2 TMEM259 PEA15 MX2	1.67e-06	200	126	7	a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	CNNM2 ARHGAP10 CDH19 ITIH3 FAT1 PELO LMNA	1.67e-06	200	126	7	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3\|Control_saline / Treatment groups by lineage, cell group, cell type	CNNM2 ARHGAP10 ITIH3 FAT1 PELO LMNA ALDOC	1.67e-06	200	126	7	b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CTU2 WNK1 LRP1B GRHL1 TRPV6 TRPV5	4.93e-06	153	126	6	79c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	5.12e-06	154	126	6	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	5.12e-06	154	126	6	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	5.31e-06	155	126	6	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	5.31e-06	155	126	6	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	LPS-antiTNF-Endothelial-Mes-Like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AKAP5 ACACB NHLRC2 CDH19 ITIH3 EPHB1	5.93e-06	158	126	6	50df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO9B HMOX1 VCAN RABGEF1 PEA15 SERPIND1	6.61e-06	161	126	6	4362fe0c151f49eae7372b9673bac64d980a8389
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	9.96e-06	173	126	6	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO5 KIF21A HNF4A ITIH3 NNT SERPIND1	1.06e-05	175	126	6	5c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGAP10 SCLY GRHL1 OTUD7A ALDOC CPNE7	1.17e-05	178	126	6	0b59e3d75b143bd7bf91a7800a49699c51e68c5a
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 KIF21A CFAP45 TMC5 MAP3K19	1.25e-05	180	126	6	adf5db5bfa9a38b1227ab0beccd8d6f3eea67ac0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNNM2 WNK1 ACOT11 TRPV6 NNT TRPV5	1.37e-05	183	126	6	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 DNAH10 LRP1B FAT1 XIRP2 OTOGL	1.41e-05	184	126	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 DNAH10 LRP1B FAT1 XIRP2 OTOGL	1.41e-05	184	126	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 DNAH10 LRP1B FAT1 XIRP2 OTOGL	1.41e-05	184	126	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	15-Airway-Epithelial-Multiciliated_cell\|Airway / Age, Tissue, Lineage and Cell class	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.46e-05	185	126	6	0998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCell	RA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	CDH19 FAT1 LMNA PTPRS VCAN MX2	1.65e-05	189	126	6	b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.75e-05	191	126	6	2a8e6d560907e71e9f6e190ca0667da804e25641
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.75e-05	191	126	6	46c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	DNAH3 DNAH10 CFAP43 TMC5 MAP3K19 AHNAK2	1.75e-05	191	126	6	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	Mild_COVID-19-Epithelial-Ciliated\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.75e-05	191	126	6	995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.75e-05	191	126	6	a37f20172b85566b9039254a89680e37fd503fd5
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.75e-05	191	126	6	2d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.75e-05	191	126	6	e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	DNAH3 DNAH10 CFAP43 TMC5 MAP3K19 AHNAK2	1.75e-05	191	126	6	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	ACACB KIF21A GREB1L FRY ACOT11 NNT	1.80e-05	192	126	6	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CHRAC1 UBA1 EHBP1L1 SPEN ALDOC	1.83e-05	114	126	5	670c9802a59b39241abf6f2c12a3d1844c7db5e5
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.85e-05	193	126	6	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	RA\|World / Chamber and Cluster_Paper	CDH19 FAT1 LMNA OTOGL PTPRS VCAN	1.91e-05	194	126	6	08f0afbb68a63150fbe107a5337299081c3f69e4
ToppCell	ASK452-Epithelial-Ciliated\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH3 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	1.91e-05	194	126	6	5aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.91e-05	194	126	6	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.96e-05	195	126	6	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.96e-05	195	126	6	0e763f36786515698b593e5c93f6a56619c1242d
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Ciliated\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.96e-05	195	126	6	cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.96e-05	195	126	6	581b04220587e1d5198b1abd6965965ace7803e7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.96e-05	195	126	6	93b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.96e-05	195	126	6	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.96e-05	195	126	6	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	THEMIS2 MYO9B ARHGAP10 HMOX1 VCAN SDCBP	1.96e-05	195	126	6	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	BL-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	1.96e-05	195	126	6	07a6bcef6af93ed87df455dee624037cb75e011a
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 MAP3K19	2.02e-05	196	126	6	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.02e-05	196	126	6	686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.02e-05	196	126	6	67aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.02e-05	196	126	6	ca56311edc6788e032e7635fa69b1e07035202b5
ToppCell	Severe_COVID-19-Epithelial-Ciliated\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.02e-05	196	126	6	1cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.02e-05	196	126	6	69f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 KIF21A C3 PLEC MAP3K19 AHNAK2	2.08e-05	197	126	6	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	wk_20-22-Epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 TMC5	2.08e-05	197	126	6	468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.08e-05	197	126	6	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 KIF21A CFAP43 CFAP45 TMC5 MAP3K19	2.08e-05	197	126	6	d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THEMIS2 MYO9B HMOX1 EHBP1L1 VCAN MX2	2.14e-05	198	126	6	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 DNAH10 CFAP45 C3 TMC5 MAP3K19	2.14e-05	198	126	6	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 DNAH10 CFAP45 C3 TMC5 MAP3K19	2.14e-05	198	126	6	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CNNM2 CDH19 ITIH3 FAT1 PELO LMNA	2.26e-05	200	126	6	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CNNM2 ARHGAP10 ITIH3 FAT1 LMNA CFAP45	2.26e-05	200	126	6	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Ciliated\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.26e-05	200	126	6	6a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CNNM2 CDH19 FAT1 PELO LMNA SYNJ2	2.26e-05	200	126	6	4e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCell	Biopsy_IPF-Epithelial-Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	DNAH3 DNAH10 KIF21A CFAP43 CFAP45 MAP3K19	2.26e-05	200	126	6	bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.26e-05	200	126	6	f1a49bc818054fb0734d3b84725ee6487b034567
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Ciliated\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.26e-05	200	126	6	d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	CNNM2 CDH19 ITIH3 FAT1 PELO ALDOC	2.26e-05	200	126	6	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 DNAH10 CFAP43 CFAP45 TMC5 MAP3K19	2.26e-05	200	126	6	cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	CNNM2 ARHGAP10 ITIH3 FAT1 PELO LMNA	2.26e-05	200	126	6	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	DIP2B SSTR5 WDR3 VCAN SPEN	4.12e-05	135	126	5	b128596653a5e3b64ed7f657bbfeda35438e2e48
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 CFAP43 CFAP45 TMC5	6.38e-05	148	126	5	d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 CFAP43 CFAP45 TMC5	6.38e-05	148	126	5	c8e93b87212f55774223caa385859c566fa1981f
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	SSTR5 WDR3 VCAN HFM1 SPEN	6.59e-05	149	126	5	768877bade04ca0321593b8470b5011ad8270431
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 CFAP43 TMC5 MAP3K19	7.02e-05	151	126	5	81cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 CFAP43 TMC5 MAP3K19	7.02e-05	151	126	5	9cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL FANCI ALDOC AGBL1 MAP3K19	7.70e-05	154	126	5	5ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM7 PRKD3 HELZ2 HFM1 B3GAT2	8.19e-05	156	126	5	895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNNM2 WNK1 LRP1B TRPV6 TRPV5	8.69e-05	158	126	5	7960337d87afecf2692ab65e5991f052ceddfacc
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD4+_Th\|normal_Pleural_Fluid / Location, Cell class and cell subclass	MPP2 AKAP5 FRY LMNA KDSR	8.96e-05	159	126	5	ebd840ac2b07e62086ee7b5bb01c21804a0fdc7b
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DNAH3 GREB1L XIRP2 GPR158 AGBL1	8.96e-05	159	126	5	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MPP2 WNK1 LRP1B TRPV6 TRPV5	8.96e-05	159	126	5	50d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF20 ZNF831 SLC25A40 GPR158 EPHB1	9.22e-05	160	126	5	5c68d6a76c59e3a7e668ae5471396478a55756ac
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF20 ZNF831 SLC25A40 GPR158 EPHB1	9.22e-05	160	126	5	0fee84844733d36805e1df90ca09478169746708
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ATP13A4 GREB1L GRHL1 TMC5 AGBL1	9.78e-05	162	126	5	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO5 MCM7 LRP1B C3 PEA15	1.01e-04	163	126	5	360cd65decda24853124f33a174f5224d7f3ce23
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO5 MCM7 LRP1B C3 PEA15	1.01e-04	163	126	5	b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCell	Ciliated_cells-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	KIF21A CFAP43 NR0B1 CFAP45 MAP3K19	1.04e-04	164	126	5	fd30c55d0d75ef8b9396435d836187168095152b
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	MPP2 AKAP5 FRY LMNA C3	1.04e-04	164	126	5	334f376350c9cf92611d0f75b2e18a102f4c116a
ToppCell	LPS-antiTNF-Endothelial-Mes-Like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AKAP5 NHLRC2 ITIH3 KCNQ4 EPHB1	1.10e-04	166	126	5	3b750d4023a0a09d86113aae5a97d84391f7b482
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-MAIT\|ICU-NoSEP / Disease, Lineage and Cell Type	ARHGAP10 KIF21A ZNF831 SYNJ2 CPNE7	1.10e-04	166	126	5	d3fa2e42497201f1ca57f4f977fbaa0def950033
Drug	Flutamide [13311-84-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	WSCD1 SCLY HMOX1 GREB1L PRKD3 ZFYVE9 VCAN CPNE7	1.21e-05	194	125	8	3885_UP
Drug	Methacholine chloride [62-51-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	MPP2 CNNM2 LONP2 FAM131A PRKD3 ZFYVE9 TMEM259 ALDOC	1.30e-05	196	125	8	3452_DN
Drug	Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A	RPS28 WNK1 LMNA SYNJ2 TMEM259 C3 TRPV6 PLEC	1.30e-05	196	125	8	3435_UP
Drug	Ethotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A	TRPC1 SCLY RPS28 HMOX1 EHBP1L1 LMNA C3 TRPV6	1.30e-05	196	125	8	3892_DN
Drug	Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; MCF7; HT_HG-U133A	SSTR5 HNF4A GREB1L EHBP1L1 SYNJ2 ARHGEF1 VPS13B AHNAK2	1.35e-05	197	125	8	3581_UP
Drug	Bromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A	FAM131A RPS28 HMOX1 WNK1 PTPRA SYNJ2 TMEM259 PLEC	1.35e-05	197	125	8	1507_DN
Drug	Demecarium bromide [56-94-0]; Down 200; 5.6uM; MCF7; HT_HG-U133A	MPP2 CNNM2 LONP2 RPS28 WNK1 EHBP1L1 TMEM259 ALDOC	1.35e-05	197	125	8	2773_DN
Drug	Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; MCF7; HT_HG-U133A	MPP2 CNNM2 MYO9B FAM131A SCLY CAMTA2 HMOX1 LMNA	1.40e-05	198	125	8	3440_DN
Drug	1,1,3-tribromopropane	TBPL2 TBP	2.99e-05	2	125	2	CID000134838
Drug	retinoic acid; Down 200; 1uM; HL60; HT_HG-U133A	FAM131A WNK1 LMNA VCAN PLEC QTRT1 CPNE7	8.49e-05	189	125	7	6170_DN
Drug	Progesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A	ACACB ARHGAP10 RPS28 EHBP1L1 VCAN QTRT1 NNT	9.68e-05	193	125	7	6646_DN
Drug	Dapsone [80-08-0]; Up 200; 16.2uM; PC3; HT_HG-U133A	CNNM2 ACACB ARHGAP10 TRPC1 HMOX1 HP1BP3 ZFYVE9	1.00e-04	194	125	7	1827_UP
Drug	Acetohexamide [968-81-0]; Down 200; 12.4uM; MCF7; HT_HG-U133A	FAM131A SLC4A2 EHBP1L1 LMNA SYNJ2 PLEC QTRT1	1.00e-04	194	125	7	1707_DN
Drug	Griseofulvin [126-07-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A	RPS28 HP1BP3 SYNJ2 TMEM259 PLEC NNT KPNB1	1.00e-04	194	125	7	2293_DN
Drug	Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; HL60; HG-U133A	WNK1 HP1BP3 FRY PTPRA SLC25A40 ACOT11 VCAN	1.00e-04	194	125	7	1413_UP
Drug	Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; MCF7; HT_HG-U133A	SCLY HP1BP3 SYNJ2 TMEM259 ARHGEF1 TRPV6 QTRT1	1.00e-04	194	125	7	2864_DN
Drug	Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; HL60; HT_HG-U133A	CNNM2 SCLY SYNJ2 ARHGEF1 C3 TMC5 CPNE7	1.03e-04	195	125	7	2333_UP
Drug	Etomidate [33125-97-2]; Down 200; 16.4uM; MCF7; HT_HG-U133A	MPP2 CNNM2 RPS28 HMOX1 ZFYVE9 SLC25A40 ARHGEF1	1.03e-04	195	125	7	7460_DN
Drug	Sotalol hydrochloride [959-24-0]; Up 200; 13uM; MCF7; HT_HG-U133A	TRPC1 NHLRC2 WNK1 EHBP1L1 SLC25A40 ACOT11 NNT	1.07e-04	196	125	7	7338_UP
Drug	Demecarium bromide [56-94-0]; Down 200; 5.6uM; PC3; HT_HG-U133A	WSCD1 TRPC1 SCLY CAMTA2 HMOX1 VCAN CFAP45	1.07e-04	196	125	7	5795_DN
Drug	Nortriptyline hydrochloride [894-71-3]; Down 200; 13.4uM; PC3; HT_HG-U133A	FMO5 ACACB MYO9B NHLRC2 WNK1 NNT SERPIND1	1.10e-04	197	125	7	7300_DN
Drug	Lymecycline [992-21-2]; Up 200; 6.6uM; MCF7; HT_HG-U133A	MPP2 WSCD1 MYO9B FRY ZFYVE9 PLEC MX2	1.10e-04	197	125	7	3514_UP
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	LONP2 TRPC1 HP1BP3 PTPRA ZFYVE9 TMEM259 AHNAK2	1.10e-04	197	125	7	1641_UP
Drug	Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; PC3; HT_HG-U133A	WSCD1 CNNM2 ARHGAP10 TRPC1 SCLY TMEM259 TRPV6	1.10e-04	197	125	7	4573_DN
Drug	Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; HL60; HT_HG-U133A	ACACB ZFYVE9 LMNA VCAN TRPV6 PLEC QTRT1	1.10e-04	197	125	7	2205_DN
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A	FAM131A RPS28 HMOX1 ZFYVE9 LMNA ARHGEF1 TRPV6	1.10e-04	197	125	7	3769_DN
Drug	Meropenem [96036-03-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A	MYO9B HMOX1 SSTR5 HP1BP3 PTPRA SLC25A40 QTRT1	1.10e-04	197	125	7	7180_UP
Drug	Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A	WSCD1 FMO5 MYO9B TRPC1 PTPRS C3 AHNAK2	1.10e-04	197	125	7	4135_UP
Drug	Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; PC3; HT_HG-U133A	FMO5 WNK1 SLC25A40 ACOT11 C3 TRPV6 KPNB1	1.10e-04	197	125	7	4506_DN
Drug	Trichlormethiazide [133-67-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A	MPP2 WSCD1 FAM131A LMNA SYNJ2 ACOT11 EPHB1	1.14e-04	198	125	7	4783_UP
Drug	Alfaxalone [23930-19-0]; Down 200; 12uM; MCF7; HT_HG-U133A	MYO9B TRPC1 WNK1 EHBP1L1 TRPV6 TMC5 KPNB1	1.14e-04	198	125	7	5451_DN
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A	MPP2 LONP2 HMOX1 SYNJ2 ARHGEF1 VCAN TMC5	1.14e-04	198	125	7	6983_UP
Drug	Bupropion hydrochloride [31677-93-7]; Down 200; 14.4uM; HL60; HG-U133A	SNX3 ZFYVE9 SLC25A40 TSR1 PEA15 NNT KPNB1	1.14e-04	198	125	7	1564_DN
Drug	Cefixime [79350-37-1]; Down 200; 8.8uM; PC3; HT_HG-U133A	MPP2 GREB1L SYNJ2 ARHGEF1 TMC5 NNT TBP	1.14e-04	198	125	7	4567_DN
Drug	Riluzole hydrochloride; Down 200; 14.8uM; HL60; HT_HG-U133A	MYO9B TMEM259 ACOT11 ARHGEF1 VCAN C3 ALDOC	1.14e-04	198	125	7	2334_DN
Drug	Baclofen (R,S) [1134-47-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A	RPS28 HMOX1 WNK1 ZFYVE9 LMNA C3 TMC5	1.17e-04	199	125	7	1536_DN
Drug	sulindac sulfone; Down 200; 50uM; MCF7; HG-U133A	THEMIS2 ACACB LONP2 PPP3CB SLC25A40 SYNJ2 PLEC	1.17e-04	199	125	7	309_DN
Drug	Gly-His-Lys acetate salt; Down 200; 1uM; PC3; HT_HG-U133A	WSCD1 DNAH3 FMO5 ACACB ARHGAP10 SSTR5 ACOT11	1.17e-04	199	125	7	6560_DN
Drug	Ifosfamide [3778-73-2]; Down 200; 15.4uM; MCF7; HT_HG-U133A	MYO9B TRPC1 FAM131A CAMTA2 ZFYVE9 LMNA ALDOC	1.17e-04	199	125	7	3485_DN
Drug	Roxithromycin [80214-83-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A	MPP2 WSCD1 TNFSF10 TRPC1 FPR2 PTPRA AHNAK2	1.17e-04	199	125	7	4778_UP
Drug	menthol	HMOX1 SPEN TRPV5 B3GAT2 KPNB1	1.19e-04	87	125	5	CID000001254
Drug	Dibucaine [85-79-0]; Up 200; 11.6uM; HL60; HG-U133A	MYO9B FPR2 PTPRA ZFYVE9 LMNA QTRT1 NNT	1.21e-04	200	125	7	1969_UP
Drug	1,1-dimethylbiguanide hydrochloride; Up 200; 0.1uM; MCF7; HG-U133A	DNAH3 ACACB MYO9B FAM131A LMNA TMEM259 NNT	1.21e-04	200	125	7	3_UP
Disease	Phelan-McDermid syndrome (implicated_via_orthology)	TCF20 SHANK3	1.70e-05	2	122	2	DOID:0080354 (implicated_via_orthology)
Disease	Ischemic stroke, fibrinogen measurement	DIP2B HNF4A SHANK3 PLEC	8.06e-05	55	122	4	EFO_0004623, HP_0002140
Disease	fibrinogen measurement, factor VII measurement	DIP2B HNF4A SHANK3 PLEC	9.93e-05	58	122	4	EFO_0004619, EFO_0004623
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	MPP2 DNAH10 TNFSF10 NHLRC2 PELO HELZ2 KPNB1	1.18e-04	264	122	7	EFO_0008317, EFO_0020944
Disease	obsolete_red blood cell distribution width	THEMIS2 DIP2B MYO9B MCM7 WNK1 HP1BP3 EHBP1L1 PTPRA KANSL1 RBM27 GPR158 TMEM259 FANCI HELZ2 HFM1 KPNB1	1.40e-04	1347	122	16	EFO_0005192
Disease	neurodegenerative disease (implicated_via_orthology)	TBPL2 TRPC1 SLC25A40 SLC25A39 TBP	3.49e-04	145	122	5	DOID:1289 (implicated_via_orthology)
Disease	pack-years measurement, systolic blood pressure	CDH19 LRP1B FRY	3.76e-04	34	122	3	EFO_0006335, EFO_0006526
Disease	serum iron measurement	ATP13A4 CDH19 LRP1B TMC5	4.55e-04	86	122	4	EFO_0006332
Disease	X-linked Adrenal Hypoplasia	NR0B1 NNT	4.67e-04	8	122	2	C0342482
Disease	SPINOCEREBELLAR ATAXIA 17	HMOX1 TBP	5.99e-04	9	122	2	C1846707
Disease	fibrinogen measurement, tissue plasminogen activator measurement	DIP2B HNF4A PLEC	8.62e-04	45	122	3	EFO_0004623, EFO_0004791
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	DIP2B HNF4A PLEC	8.62e-04	45	122	3	EFO_0004623, EFO_0004792
Disease	Salivary Gland Neoplasms	FAT1 VCAN SPEN	9.79e-04	47	122	3	C0036095
Disease	anxiety measurement	CNNM2 TRPV6 AGBL1 TRPV5	1.07e-03	108	122	4	EFO_0009863
Disease	hepatocellular carcinoma (biomarker_via_orthology)	MCM7 HNF4A C3 ALDOC	1.07e-03	108	122	4	DOID:684 (biomarker_via_orthology)
Disease	fibrinogen measurement	DIP2B HNF4A SHANK3 PLEC	1.11e-03	109	122	4	EFO_0004623
Disease	monocyte count	THEMIS2 TNFSF10 DPP8 WNK1 PTPRA LMNA VCAN CFAP45 C3 HFM1 KDSR SERPIND1 SDCBP MAP3K19	1.13e-03	1320	122	14	EFO_0005091
Disease	pneumonia, COVID-19	CHRAC1 LRP1B FAT1 VPS13B	1.27e-03	113	122	4	EFO_0003106, MONDO_0100096
Disease	developmental and epileptic encephalopathy (implicated_via_orthology)	KCNQ4 MX2	1.28e-03	13	122	2	DOID:0112202 (implicated_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	ACACB DNAH10 NHLRC2 HNF4A HELZ2 KPNB1	1.36e-03	291	122	6	EFO_0008317, EFO_0020946
Disease	sickle cell anemia (is_marker_for)	HMOX1 C3	1.49e-03	14	122	2	DOID:10923 (is_marker_for)
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	DIP2B HNF4A PLEC	1.63e-03	56	122	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	Malignant neoplasm of breast	THEMIS2 CTU2 TNFSF10 PIGS FAM131A HMOX1 WNK1 SYNJ2 OTOGL N4BP2 SPEN VPS13B	1.68e-03	1074	122	12	C0006142
Disease	triiodothyronine measurement	MPP2 AGBL1	1.96e-03	16	122	2	EFO_0008392
Disease	Monogenic diabetes	HNF4A LMNA	1.96e-03	16	122	2	C3888631
Disease	Insulin Resistance	ACACB HMOX1 C3	1.99e-03	60	122	3	C0021655
Disease	Insulin Sensitivity	ACACB HMOX1 C3	1.99e-03	60	122	3	C0920563
Disease	response to radiation, Urinary retention	LRP1B PTPRS	2.21e-03	17	122	2	GO_0009314, HP_0000016
Disease	phosphatidylcholine 40:6 measurement	PTPRA TMC5	2.21e-03	17	122	2	EFO_0010389
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	ACACB DNAH10 NHLRC2 ITIH3 KPNB1	2.48e-03	225	122	5	EFO_0008317, EFO_0010351
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	TNFSF10 NHLRC2 HNF4A HELZ2 KPNB1	2.48e-03	225	122	5	EFO_0008317, EFO_0020947
Disease	Tourette syndrome, schizophrenia	TCF20 DNAH10	2.48e-03	18	122	2	EFO_0004895, MONDO_0005090
Disease	venous thromboembolism, fibrinogen measurement	DIP2B HNF4A SHANK3	2.72e-03	67	122	3	EFO_0004286, EFO_0004623

Protein segments in the cluster

Peptide	Gene	Start	Entry
MPKTLRTRLADTVVL	ACTL10	151	Q5JWF8
TVPLRMVVLTRIFTD	SLC4A2	1196	P04920
PVLRLTSAMTREVAT	ARHGEF1	706	Q92888
ILQTEVERLRMKTFP	CFAP43	1646	Q8NDM7
TETPLVTARMILESK	VCAN	516	P13611
PEEIAMATVTALRRT	ALDOC	246	P09972
PVLEELISARIRTVM	ATP13A4	701	Q4VNC1
EARVVVLVESMIPRS	CAMTA2	681	O94983
IRMNKTVAVRTLDPE	C3	936	P01024
RMVPAEKTRVESVEL	ACOT11	211	Q8WXI4
MAPGEVTITVRLIRS	C2orf76	1	Q3KRA6
TRVMVETKTKPLAER	ARMCX5	86	Q6P1M9
KSMEPVISVVLQILR	AGBL1	251	Q96MI9
GEKVEDSTMPIRRTV	HP1BP3	31	Q5SSJ5
ITRVVLEPDSRKRAM	RBM27	551	Q9P2N5
AITDIIEMDSKRVPR	RABGEF1	271	Q9UJ41
IRSVRTVMRVPLIIV	IER3IP1	56	Q9Y5U9
MKTLEAQLTPRVVER	SERPIND1	366	P05546
EATVPMLQRTKSRIE	LRRC8A	206	Q8IWT6
RAIRFVVMVTPEDLK	ACACB	291	O00763
REIMALSVTETLIKP	ARHGAP10	101	A1A4S6
IRLEGVVTKSRPVMI	EPHB1	681	P54762
RETPAEKVISVRLMA	FAT1	2556	Q14517
VATAMARVLRETKPI	FANCI	1236	Q9NVI1
AVARSVLVMTVRPED	NPHS1	296	O60500
MLVDLVSPRKIISFV	OR10A7	81	Q8NGE5
EEVAMRKLVRSVTVV	LMNA	536	P02545
SLEERFKMTIPLLVR	LONP2	206	Q86WA8
SVVIETKISRPMALT	LRP1B	3166	Q9NZR2
AMIKELLDTRIRPTV	NFU1	171	Q9UMS0
GRSIMRRITEIPETV	GPR158	751	Q5T848
TPEERLKVAITMLTA	FPR2	186	P25090
LTVDDIMPAVKTVIR	KCNQ4	521	P56696
IMPAVKTVIRSIRIL	KCNQ4	526	P56696
LITRDMVRELIVPTE	CFAP45	81	Q9UL16
MSRVSIRILDELVLP	HNF4A	261	P41235
IFEISRRPDLLTMVV	PEA15	66	Q15121
ELMGILPTVRSTRIV	INTS2	346	Q9H0H0
ATLPTVRMIVDVSKA	DIP2B	1086	Q9P265
ARVLMTRKTEIIVPE	EHBP1L1	861	Q8N3D4
RMLTPETTKEIKLVE	HERVK_113	306	P63132
VIPMSVAATTRVEKL	KANSL1	866	Q7Z3B3
LPERITKFMVTQILV	PRKD3	671	O94806
ESPIVRSLAKVIMVL	MPP2	41	Q14168
RRPIVVVADTMLRDS	OTUD7A	316	Q8TE49
SMVRELIDKVRTVFV	MMEL1	466	Q495T6
KVEEPRKRETVSIML	GREB1L	1416	Q9C091
LETKMVSVLPIFRSE	NHLRC2	561	Q8NBF2
IVTRVSEVKPKMVVA	MCM7	166	P33993
PQLKVVERTRTATML	PTPRS	141	Q13332
RGPTLEVVVSRMKTV	HFM1	421	A2PYH4
VSEPSMLQKILTTRR	NR0B1	311	P51843
PISKVRSVIMVVFAE	GRHL1	296	Q9NZI5
AKVSELIIPTMETAR	DNAH3	2041	Q8TD57
TDDRIRKPLMTRVVE	FMO5	491	P49326
ILIVIIMLDVDTRRP	B3GAT2	16	Q9NPZ5
AIVRASRLPMSIIIV	CPNE7	531	Q9UBL6
VEIIHVTSPMLETRR	DPP8	311	Q6V1X1
TTVSRTKPALVLMEL	TMEM132E-DT	151	A2RUQ5
MLPKSRRALTIQEIA	FAM131A	86	Q6UXB0
ESKRMEPIAIIITDT	AKAP5	331	P24588
MQVTVRSKERTPVDV	COPG2	851	Q9UBF2
MELITILEKTVSPDR	KPNB1	1	Q14974
TRQRLSIPVMVVTLD	TMEM259	226	Q4ZIN3
MTPAVRQRVIEEAKT	HMOX1	191	P09601
VAMVVKLSEVTFRPL	HEATR1	1901	Q9H583
LVPLMRLESIEITES	FRY	971	Q5TBA9
MASLEVIRRPETKVL	HELZ2	556	Q9BYK8
ELVTRITMPLSKNDR	DNAH10	1721	Q8IVF4
LRREKTMIEVEAPIT	PPP3CB	81	P16298
ITMTIRDRPFERTIT	SDCBP	186	O00560
RRVIQTMGKDLTPIT	SLC20A1	581	Q8WUM9
SKLRRDVMPETIFQI	CDH9	686	Q9ULB4
VITTMKERRVGRIVF	KDSR	156	Q06136
PTTGVIRISSKMDRE	CDH19	201	Q9H159
VVVVRPMRDHTLKEV	CTU2	301	Q2VPK5
LTMRPLVLQKEESSR	MAP3K19	136	Q56UN5
EIEKSFEVTMRRPVR	OTOGL	1716	Q3ZCN5
RRDETPIIAVMVALS	PTPRA	146	P18433
ASVLPVRVEVDMVRV	PIGS	371	Q96S52
KTTVLAMDQVPRVTI	NNT	171	Q13423
PRAMAVLESLRVIIT	QARS1	566	P47897
LMSAVRTSIVEKRFP	QTRT1	356	Q9BXR0
ALLVTPRILKAMTER	SYNJ2	506	O15056
VTVISPLELIRTKMQ	SLC25A40	156	Q8TBP6
REGTMELRTTPQLKV	LTB4R2	321	Q9NPC1
IVVSTRTGEVMRILP	NDUFS1	261	P28331
RIPERSTSIVIMLTD	ITIH3	381	Q06033
LAMTRVVPDKLRSLA	SLCO6A1	601	Q86UG4
LVTPSMTLTRAKVEV	PELO	151	Q9BRX2
RSERKVTRMVLVVVL	SSTR5	241	P35346
RVMVTSAARTELILP	AHNAK2	5761	Q8IVF2
LSRIRVIMKSSPEVS	CHRAC1	21	Q9NRG0
LRTKTVEDVMTPLRD	CNNM2	441	Q9H8M5
MSSLIRRVISTAKAP	RIDA	1	P52758
RSSRPTIVKLMERIQ	TRPC1	136	P48995
MSPATLRRQIKIETR	XIRP2	3041	A4UGR9
ISIIVRDALMQPVRK	VPS4B	341	O75351
LAAVRPTTRLVTIML	SCLY	181	Q96I15
SVDPDRMVIKRVVLS	TSR1	686	Q2NL82
RLELMPCVVLTRVKE	SPEN	871	Q96T58
SEEPKVKEMVRILRT	MRPL10	156	Q7Z7H8
VTVISPLELMRTKLQ	SLC25A39	176	Q9BZJ4
RLVMKVVSVTRKPEE	SHANK3	656	Q9BYB0
KTEEVTALRRQVRPM	KIF21A	826	Q7Z4S6
IMRIREPRTTALIFS	TBP	201	P20226
MRRTIVKIPSTLEVD	THEMIS2	216	Q5TEJ8
QIVATTVMLERKLPR	TRPV6	636	Q9H1D0
MAETVADTRRLITKP	SNX3	1	O60493
RRVVIVDPETGKEMS	PLEC	4276	Q15149
VIVSREAMTGRVEKP	TCF20	606	Q9UGU0
LDQPMTEIVSRVSKR	UBA1	1011	P22314
TSVIRIFIPKTEEMQ	VPS13B	1551	Q7Z7G8
SLIPMTSRDRIKAIR	TMC5	356	Q6UXY8
VARLREAVSMETKIP	USP31	346	Q70CQ4
EELRRSLVPTLREMV	WSCD1	491	Q658N2
RRTLSPEMITVTSAV	WNK1	1801	Q9H4A3
QMLVPVIEKLRETTI	WDR3	871	Q9UNX4
IVREMDKRTVKDISP	ZNF831	1386	Q5JPB2
QLVRKMILRTSEETI	TNFSF10	86	P50591
MDTSRVQPIKLARVT	RPS28	1	P62857
LVVDMEVRKTSIKIP	ZFYVE9	1126	O95405
AVIMRIREPRTTALI	TBPL2	236	Q6SJ96
QVVATTVMLERKLPR	TRPV5	596	Q9NQA5
SLVILSKRIPETMAT	VN1R2	136	Q8NFZ6
TVPRLAERLTTELIM	MX2	366	P20592
IIMSSSVPEKIERIE	N4BP2	581	Q86UW6
FVTVRVKTPRRTPIM	MYO9B	2051	Q13459