Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine kinase activity	CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MTOR MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB	8.90e-07	363	177	15	GO:0106310
GeneOntologyMolecularFunction	molecular tag activity	RPS27A UBA52 UBB UBC	5.57e-06	14	177	4	GO:0141047
GeneOntologyMolecularFunction	protein tag activity	RPS27A UBA52 UBB UBC	5.57e-06	14	177	4	GO:0031386
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MTOR MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB	1.09e-05	446	177	15	GO:0004674
GeneOntologyMolecularFunction	protein kinase activity	EPHB3 CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MTOR MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB EPHB1	2.57e-05	600	177	17	GO:0004672
GeneOntologyMolecularFunction	sulfate:bicarbonate antiporter activity	SLC26A1 SLC26A6	7.81e-05	2	177	2	GO:0015383
GeneOntologyMolecularFunction	polyspecific organic cation:proton antiporter activity	SLC47A2 SLC47A1	7.81e-05	2	177	2	GO:0140968
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	EPHB3 CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MTOR MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB EPHB1	1.97e-04	709	177	17	GO:0016773
GeneOntologyMolecularFunction	antiporter activity	SLC26A1 SLC47A2 CLCN4 CLCN7 SLC24A2 SLC47A1 SLC26A6	2.33e-04	138	177	7	GO:0015297
GeneOntologyMolecularFunction	phosphatidylinositol N-acetylglucosaminyltransferase activity	PIGQ PIGA	4.63e-04	4	177	2	GO:0017176
GeneOntologyMolecularFunction	kinase activity	EPHB3 CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MTOR MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB EPHB1	4.67e-04	764	177	17	GO:0016301
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	EPHB3 CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 PARP4 MAPK14 BRAF MTOR MARK4 POLI SIK2 PRKD1 MAP3K15 MAPK1 IKBKB EPHB1	6.83e-04	938	177	19	GO:0016772
GeneOntologyMolecularFunction	osmolarity-sensing monoatomic cation channel activity	TRPA1 SCN7A	7.68e-04	5	177	2	GO:1990760
GeneOntologyMolecularFunction	osmosensor activity	TRPA1 SCN7A	1.14e-03	6	177	2	GO:0005034
GeneOntologyBiologicalProcess	organelle assembly	INTU LRFN1 HDAC6 IFT57 RPS3 CEP162 SYNE1 DNAH2 RNF213 TOGARAM1 ODAD2 DDB1 CFAP54 CLCN4 TBC1D10A MTOR CASKIN1 MARK4 TMF1 GOLGA8B PRKD1 ATXN10 PLEC NOP2 DHX29	8.78e-06	1138	172	25	GO:0070925
GeneOntologyBiologicalProcess	cilium organization	INTU HDAC6 IFT57 CEP162 SYNE1 DNAH2 TOGARAM1 ODAD2 CFAP54 CLCN4 TBC1D10A MARK4 ROPN1B ATXN10 ROPN1	1.14e-05	476	172	15	GO:0044782
GeneOntologyBiologicalProcess	proteolysis involved in protein catabolic process	UBR1 HDAC6 RNF213 PSMD3 RPS27A CUL7 DDB1 ADAMTS12 UBA52 UBB UBC PSME4 PHF20L1 RNF10 TMF1 KIF14 UBR3 RNF133 ANKS1A	5.01e-05	812	172	19	GO:0051603
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	DPP10 TRPA1 ANK2 RIPK1 TRPC4 ABCC5 BPIFA1 SLC26A1 SLC47A2 RYR3 CLCN4 CLCN7 SLC24A2 MTOR KCNJ15 SCN7A UBR3 SLC47A1 PRKD1 IKBKB DMAC2L CNGA1 SLC26A6	5.53e-05	1115	172	23	GO:0034220
GeneOntologyBiologicalProcess	microtubule-based process	INTU HDAC6 IFT57 MARK1 RPS3 DNAH2 TOGARAM1 NUF2 ODAD2 CUL7 DDB1 UBB CFAP54 DST MARK4 TMF1 GOLGA8B KIF14 MACF1 ROPN1B DNAH9 ROPN1	7.24e-05	1058	172	22	GO:0007017
GeneOntologyBiologicalProcess	peptidyl-serine modification	HDAC6 RIPK1 MARK1 MAPK14 BRAF MTOR PRKD1 MAPK1 MAD2L2 IKBKB MGAT5B	7.89e-05	319	172	11	GO:0018209
GeneOntologyBiologicalProcess	ephrin receptor signaling pathway	EPHB3 KALRN ANKS1B ANKS1A EPHB1	8.65e-05	54	172	5	GO:0048013
GeneOntologyBiologicalProcess	cilium assembly	INTU HDAC6 IFT57 CEP162 SYNE1 DNAH2 TOGARAM1 ODAD2 CFAP54 CLCN4 TBC1D10A MARK4 ATXN10	9.39e-05	444	172	13	GO:0060271
GeneOntologyBiologicalProcess	negative regulation of keratinocyte proliferation	INTU EPPK1 IFT57 CASK	9.42e-05	29	172	4	GO:0010839
GeneOntologyBiologicalProcess	regulation of keratinocyte proliferation	INTU EPPK1 IFT57 CASK PRKD1	1.03e-04	56	172	5	GO:0010837
GeneOntologyBiologicalProcess	modification-dependent protein catabolic process	UBR1 HDAC6 RNF213 PSMD3 RPS27A CUL7 DDB1 UBA52 UBB UBC PHF20L1 RNF10 KIF14 UBR3 RNF133 ANKS1A	1.15e-04	651	172	16	GO:0019941
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	DPP10 TRPA1 ANK2 TRPC4 ABCC5 BPIFA1 SLC26A1 SLC47A2 RYR3 CLCN4 CLCN7 SLC24A2 MTOR KCNJ15 SCN7A UBR3 SLC47A1 PRKD1 DMAC2L CNGA1 SLC26A6	1.18e-04	1017	172	21	GO:0098660
GeneOntologyBiologicalProcess	modification-dependent macromolecule catabolic process	UBR1 HDAC6 RNF213 PSMD3 RPS27A CUL7 DDB1 UBA52 UBB UBC PHF20L1 RNF10 KIF14 UBR3 RNF133 ANKS1A	1.26e-04	656	172	16	GO:0043632
GeneOntologyBiologicalProcess	monoatomic anion transport	TRPA1 RIPK1 ABCC5 SLC26A1 CLCN4 CLCN7 MTOR SLC26A6	1.54e-04	183	172	8	GO:0006820
GeneOntologyBiologicalProcess	protein catabolic process	UBR1 HDAC6 RIPK1 RNF213 PSMD3 RPS27A CUL7 DDB1 ADAMTS12 UBA52 UBB UBC PSME4 PHF20L1 MTOR RNF10 TMF1 KIF14 UBR3 MAD2L2 RNF133 ANKS1A	1.54e-04	1115	172	22	GO:0030163
GeneOntologyBiologicalProcess	positive regulation of nervous system development	EPHB3 HDAC6 KALRN RASSF10 CUL7 CASK LRRN3 BRAF MTOR GOLGA8B MACF1 EPHB1	2.10e-04	418	172	12	GO:0051962
GeneOntologyBiologicalProcess	cell division	INTU RPS3 NUF2 CUL7 PIK3R4 CXCR5 MARK4 GOLGA8B KIF14 ROPN1B MICAL3 PADI6 ATXN10 MAD2L2 PLEC IQGAP3	2.50e-04	697	172	16	GO:0051301
GeneOntologyBiologicalProcess	microtubule-based movement	INTU HDAC6 IFT57 DNAH2 ODAD2 UBB CFAP54 DST TMF1 KIF14 ROPN1B DNAH9 ROPN1	2.62e-04	493	172	13	GO:0007018
GeneOntologyBiologicalProcess	peptidyl-serine phosphorylation	HDAC6 RIPK1 MARK1 MAPK14 BRAF MTOR PRKD1 MAPK1 MAD2L2 IKBKB	2.64e-04	307	172	10	GO:0018105
GeneOntologyCellularComponent	basal plasma membrane	EPPK1 ANK2 TRPC4 ABCC5 SLC26A1 CASK DST STXBP3 TJP1 SLC47A1 PLEC SLC26A6 SLC27A5	1.36e-05	354	181	13	GO:0009925
GeneOntologyCellularComponent	basal part of cell	EPPK1 ANK2 TRPC4 ABCC5 SLC26A1 CASK DST STXBP3 TJP1 SLC47A1 PLEC SLC26A6 SLC27A5	2.70e-05	378	181	13	GO:0045178
GeneOntologyCellularComponent	cytosolic small ribosomal subunit	RPS3 RPS27A UBA52 UBB DHX29	4.73e-05	46	181	5	GO:0022627
GeneOntologyCellularComponent	hemidesmosome	EPPK1 DST PLEC	1.00e-04	11	181	3	GO:0030056
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	HDAC6 IFT57 CEP162 DNAH2 TOGARAM1 ODAD2 PIK3R4 CFAP54 DST MAPK1 DNAH9	1.05e-04	317	181	11	GO:0032838
GeneOntologyCellularComponent	cilium	INTU HDAC6 IFT57 CEP162 DNAH2 TOGARAM1 PRAMEF12 ODAD2 CASK PIK3R4 CFAP54 CLCN4 MARK4 ROPN1B ATXN10 DNAH9 ROPN1 CNGA1 SLC26A6	3.04e-04	898	181	19	GO:0005929
GeneOntologyCellularComponent	cytoplasmic region	HDAC6 IFT57 CEP162 DNAH2 TOGARAM1 ODAD2 PIK3R4 CFAP54 DST MAPK1 DNAH9	3.15e-04	360	181	11	GO:0099568
GeneOntologyCellularComponent	axoneme	IFT57 CEP162 DNAH2 TOGARAM1 ODAD2 PIK3R4 CFAP54 DNAH9	4.57e-04	207	181	8	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	IFT57 CEP162 DNAH2 TOGARAM1 ODAD2 PIK3R4 CFAP54 DNAH9	4.72e-04	208	181	8	GO:0097014
GeneOntologyCellularComponent	basolateral plasma membrane	EPPK1 ANK2 TRPC4 ABCC5 SLC26A1 CASK STXBP3 TJP1 SLC47A1 SLC26A6	4.95e-04	320	181	10	GO:0016323
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	CYP1B1 PIGB SYNE1 CYP21A2 ARMC10 RPS27A SSR1 RYR3 FZD6 PIGQ UBA52 UBB UBC DST PIGA CLCN4 MTOR TMEM208 SIK2 DIO1 UGT2B10 PNPLA7 RNF133 SLC27A5	4.95e-04	1327	181	24	GO:0042175
GeneOntologyCellularComponent	small ribosomal subunit	RPS3 RPS27A UBA52 UBB DHX29	6.93e-04	81	181	5	GO:0015935
GeneOntologyCellularComponent	sperm cytoplasmic droplet	ROPN1B ROPN1	7.33e-04	5	181	2	GO:0097598
GeneOntologyCellularComponent	cytosolic ribosome	RPS3 RPS27A UBA52 UBB RNF10 DHX29	7.45e-04	124	181	6	GO:0022626
GeneOntologyCellularComponent	organelle outer membrane	SYNE1 ARMC10 RPS27A UBA52 UBB UBC MTOR UGT2B10 PLEC	7.53e-04	279	181	9	GO:0031968
GeneOntologyCellularComponent	outer membrane	SYNE1 ARMC10 RPS27A UBA52 UBB UBC MTOR UGT2B10 PLEC	7.92e-04	281	181	9	GO:0019867
GeneOntologyCellularComponent	endoplasmic reticulum membrane	CYP1B1 PIGB CYP21A2 ARMC10 RPS27A SSR1 RYR3 FZD6 PIGQ UBA52 UBB UBC DST PIGA CLCN4 MTOR TMEM208 SIK2 DIO1 UGT2B10 PNPLA7 RNF133 SLC27A5	8.19e-04	1293	181	23	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	CYP1B1 PIGB CYP21A2 ARMC10 RPS27A SSR1 RYR3 FZD6 PIGQ UBA52 UBB UBC DST PIGA CLCN4 MTOR TMEM208 SIK2 DIO1 UGT2B10 PNPLA7 RNF133 SLC27A5	8.71e-04	1299	181	23	GO:0098827
GeneOntologyCellularComponent	apical plasma membrane	DPEP1 TRPA1 ANK2 ABCC5 SLC47A2 FZD6 STXBP3 TJP1 SLC47A1 PLEC ABCG5 SLC26A6	1.14e-03	487	181	12	GO:0016324
GeneOntologyCellularComponent	apicolateral plasma membrane	EPPK1 FZD6 TJP1	1.78e-03	28	181	3	GO:0016327
GeneOntologyCellularComponent	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	PIGQ PIGA	2.02e-03	8	181	2	GO:0000506
HumanPheno	Aplasia/Hypoplasia of fingers	PIGB INTU IFT57 CUL7 RYR3 CASK FANCD2 PIGQ PIGA CLCN7 MTOR SMARCB1 MAPK1 MAD2L2 MCTP2	2.65e-05	366	63	15	HP:0006265
HumanPheno	Short finger	PIGB INTU IFT57 CUL7 RYR3 CASK FANCD2 PIGQ PIGA CLCN7 MTOR SMARCB1 MAPK1 MCTP2	3.00e-05	325	63	14	HP:0009381
HumanPheno	Brachydactyly (hand)	PIGB INTU ADAMTS2 IFT57 CUL7 RYR3 CASK FANCD2 PIGQ PIGA CLCN7 MTOR SMARCB1 PRKD1 MAPK1 MCTP2	4.47e-05	430	63	16	HP:0100667
Domain	NPIP	NPIPB15 NPIPB9 NPIPB3 NPIPB5 NPIPB2 NPIPB13	1.88e-09	14	177	6	IPR009443
Domain	-	EPPK1 DST MACF1 PLEC	1.15e-07	6	177	4	3.90.1290.10
Domain	ARM-type_fold	DOCK8 RANBP6 ARMC10 TOGARAM1 ODAD2 CUL7 RYR3 PIK3R4 FOCAD AP4E1 PSME4 MTOR UTP20 ATXN10 TARBP1 TANGO6	1.53e-07	339	177	16	IPR016024
Domain	Plectin	EPPK1 DST MACF1 PLEC	2.67e-07	7	177	4	PF00681
Domain	Plectin_repeat	EPPK1 DST MACF1 PLEC	2.67e-07	7	177	4	IPR001101
Domain	PLEC	EPPK1 DST MACF1 PLEC	2.67e-07	7	177	4	SM00250
Domain	ARM-like	DOCK8 RANBP6 ARMC10 TOGARAM1 ODAD2 CUL7 PIK3R4 AP4E1 PSME4 MTOR UTP20 ATXN10 TARBP1 TANGO6	3.05e-07	270	177	14	IPR011989
Domain	HEAT_REPEAT	RANBP6 TOGARAM1 ODAD2 PIK3R4 PSME4 MTOR UTP20 TANGO6	3.18e-07	70	177	8	PS50077
Domain	Kinase-like_dom	EPHB3 CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 DST BRAF MTOR MARK4 SIK2 MACF1 PRKD1 MAP3K15 MAPK1 IKBKB EPHB1	1.00e-06	542	177	19	IPR011009
Domain	-	RANBP6 ARMC10 TOGARAM1 ODAD2 CUL7 PIK3R4 AP4E1 PSME4 MTOR UTP20 ATXN10 TANGO6	1.42e-06	222	177	12	1.25.10.10
Domain	Ubiquitin_CS	RPS27A UBA52 UBB UBC	1.57e-06	10	177	4	IPR019954
Domain	Ubiquitin	RPS27A UBA52 UBB UBC	2.44e-06	11	177	4	IPR019956
Domain	Spectrin_repeat	KALRN SYNE1 DST MACF1 PLEC	7.13e-06	29	177	5	IPR002017
Domain	Ser/Thr_kinase_AS	CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB	8.13e-06	357	177	14	IPR008271
Domain	S_TKc	CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB	8.66e-06	359	177	14	SM00220
Domain	PROTEIN_KINASE_ST	CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB	9.51e-06	362	177	14	PS00108
Domain	SPEC	KALRN SYNE1 DST MACF1 PLEC	1.18e-05	32	177	5	SM00150
Domain	Spectrin/alpha-actinin	KALRN SYNE1 DST MACF1 PLEC	1.18e-05	32	177	5	IPR018159
Domain	Pkinase	CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB	1.69e-05	381	177	14	PF00069
Domain	Prot_kinase_dom	EPHB3 CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB EPHB1	1.76e-05	489	177	16	IPR000719
Domain	HEAT	RANBP6 TOGARAM1 ODAD2 PIK3R4 MTOR UTP20	1.79e-05	58	177	6	IPR000357
Domain	PROTEIN_KINASE_DOM	EPHB3 CDK9 RIPK1 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB EPHB1	1.94e-05	493	177	16	PS50011
Domain	PROTEIN_KINASE_ATP	EPHB3 CDK9 KALRN MARK1 CASK PIK3R4 MAPK14 BRAF MARK4 SIK2 PRKD1 MAP3K15 MAPK1 IKBKB EPHB1	3.29e-05	459	177	15	PS00107
Domain	CH	SYNE1 DST MACF1 MICAL3 PLEC IQGAP3	3.46e-05	65	177	6	SM00033
Domain	CH	SYNE1 DST MACF1 MICAL3 PLEC IQGAP3	5.28e-05	70	177	6	PF00307
Domain	-	SYNE1 DST MACF1 MICAL3 PLEC IQGAP3	5.72e-05	71	177	6	1.10.418.10
Domain	Spectrin	KALRN SYNE1 DST MACF1	6.00e-05	23	177	4	PF00435
Domain	ACTININ_2	SYNE1 DST MACF1 PLEC	6.00e-05	23	177	4	PS00020
Domain	ACTININ_1	SYNE1 DST MACF1 PLEC	6.00e-05	23	177	4	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 DST MACF1 PLEC	6.00e-05	23	177	4	IPR001589
Domain	CH	SYNE1 DST MACF1 MICAL3 PLEC IQGAP3	6.70e-05	73	177	6	PS50021
Domain	CH-domain	SYNE1 DST MACF1 MICAL3 PLEC IQGAP3	7.80e-05	75	177	6	IPR001715
Domain	ubiquitin	RPS27A UBA52 UBB UBC IKBKB	8.03e-05	47	177	5	PF00240
Domain	MATE_fam	SLC47A2 SLC47A1	8.93e-05	2	177	2	IPR002528
Domain	MatE	SLC47A2 SLC47A1	8.93e-05	2	177	2	PF01554
Domain	ANKS1	ANKS1B ANKS1A	8.93e-05	2	177	2	IPR033635
Domain	Ubiquitin_dom	RPS27A UBA52 UBB UBC IKBKB	2.20e-04	58	177	5	IPR000626
Domain	Protein_kinase_ATP_BS	EPHB3 CDK9 KALRN MARK1 MAPK14 BRAF MARK4 SIK2 PRKD1 MAP3K15 MAPK1 EPHB1	2.75e-04	379	177	12	IPR017441
Domain	UBIQUITIN_1	RPS27A UBA52 UBB UBC	4.03e-04	37	177	4	PS00299
Domain	SAM_1	EPHB3 ANKS1B CASKIN1 ANKS1A EPHB1	4.65e-04	68	177	5	PF00536
Domain	MARK/par1	MARK1 MARK4	5.29e-04	4	177	2	IPR033624
Domain	UBQ	RPS27A UBA52 UBB UBC	7.21e-04	43	177	4	SM00213
Domain	UBA	MARK1 DHX57 MARK4 SIK2	7.87e-04	44	177	4	IPR015940
Domain	SAM/pointed	EPHB3 ANKS1B CASKIN1 MAP3K15 ANKS1A EPHB1	8.73e-04	117	177	6	IPR013761
Domain	KA1	MARK1 MARK4	8.76e-04	5	177	2	PF02149
Domain	KA1_dom	MARK1 MARK4	8.76e-04	5	177	2	IPR001772
Domain	CPSASE_1	CPS1 PCCA	8.76e-04	5	177	2	PS00866
Domain	KA1	MARK1 MARK4	8.76e-04	5	177	2	PS50032
Domain	-	MARK1 MARK4	8.76e-04	5	177	2	3.30.310.80
Domain	UBA	MARK1 DHX57 MARK4 SIK2	1.01e-03	47	177	4	PS50030
Domain	GAR	DST MACF1	1.31e-03	6	177	2	PS51460
Domain	GAS2	DST MACF1	1.31e-03	6	177	2	PF02187
Domain	CPSASE_2	CPS1 PCCA	1.31e-03	6	177	2	PS00867
Domain	-	DST MACF1	1.31e-03	6	177	2	3.30.920.20
Domain	GAS_dom	DST MACF1	1.31e-03	6	177	2	IPR003108
Domain	GAS2	DST MACF1	1.31e-03	6	177	2	SM00243
Domain	SAM	EPHB3 ANKS1B CASKIN1 ANKS1A EPHB1	1.50e-03	88	177	5	SM00454
Domain	Ank	TRPA1 ANK2 TRPC4 ANKS1B CASKIN1 NFKB2 ANKRD36 ANKS1A	1.52e-03	228	177	8	PF00023
Domain	UBIQUITIN_2	RPS27A UBA52 UBB UBC	1.70e-03	54	177	4	PS50053
Domain	S04_transporter_CS	SLC26A1 SLC26A6	1.82e-03	7	177	2	IPR018045
Domain	KA1/Ssp2_C	MARK1 MARK4	1.82e-03	7	177	2	IPR028375
Domain	CbamoylP_synth_lsu-like_ATP-bd	CPS1 PCCA	1.82e-03	7	177	2	IPR005479
Domain	BC-like_N	CPS1 PCCA	1.82e-03	7	177	2	IPR005481
Domain	ZnF_UBR1	UBR1 UBR3	1.82e-03	7	177	2	SM00396
Domain	CPSase_L_D2	CPS1 PCCA	1.82e-03	7	177	2	PF02786
Domain	ZF_UBR	UBR1 UBR3	1.82e-03	7	177	2	PS51157
Domain	zf-UBR	UBR1 UBR3	1.82e-03	7	177	2	PF02207
Domain	Biotin_carb_N	CPS1 PCCA	1.82e-03	7	177	2	PF00289
Domain	Znf_UBR	UBR1 UBR3	1.82e-03	7	177	2	IPR003126
Domain	Ubiquitin-rel_dom	RASSF10 RPS27A UBA52 UBB UBC BRAF IKBKB	1.89e-03	184	177	7	IPR029071
Domain	DEATH	ANK2 RIPK1 NFKB2	2.07e-03	27	177	3	SM00005
Domain	SAM_DOMAIN	EPHB3 ANKS1B CASKIN1 ANKS1A EPHB1	2.10e-03	95	177	5	PS50105
Domain	SAM	EPHB3 ANKS1B CASKIN1 ANKS1A EPHB1	2.31e-03	97	177	5	IPR001660
Domain	DHC_N1	DNAH2 DNAH9	2.41e-03	8	177	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH2 DNAH9	2.41e-03	8	177	2	IPR013594
Domain	AAA	ABCA13 DNAH2 ABCC5 RNF213 DNAH9 ABCG5	2.52e-03	144	177	6	SM00382
Domain	AAA+_ATPase	ABCA13 DNAH2 ABCC5 RNF213 DNAH9 ABCG5	2.52e-03	144	177	6	IPR003593
Domain	-	TRPA1 ANK2 TRPC4 ANKS1B CASKIN1 NFKB2 ANKRD36 ANKS1A	2.57e-03	248	177	8	1.25.40.20
Domain	ANK	TRPA1 ANK2 TRPC4 ANKS1B CASKIN1 NFKB2 ANKRD36 ANKS1A	2.76e-03	251	177	8	SM00248
Domain	ANK_REPEAT	TRPA1 ANK2 TRPC4 ANKS1B CASKIN1 NFKB2 ANKRD36 ANKS1A	2.90e-03	253	177	8	PS50088
Domain	Ankyrin_rpt-contain_dom	TRPA1 ANK2 TRPC4 ANKS1B CASKIN1 NFKB2 ANKRD36 ANKS1A	2.97e-03	254	177	8	IPR020683
Domain	ANK_REP_REGION	TRPA1 ANK2 TRPC4 ANKS1B CASKIN1 NFKB2 ANKRD36 ANKS1A	2.97e-03	254	177	8	PS50297
Domain	Cl-channel_core	CLCN4 CLCN7	3.08e-03	9	177	2	IPR014743
Domain	-	CLCN4 CLCN7	3.08e-03	9	177	2	1.10.3080.10
Domain	Voltage_CLC	CLCN4 CLCN7	3.08e-03	9	177	2	PF00654
Domain	Cl-channel_volt-gated	CLCN4 CLCN7	3.08e-03	9	177	2	IPR001807
Domain	ZU5	ANK2 TJP1	3.08e-03	9	177	2	SM00218
Domain	-	EPHB3 ANKS1B CASKIN1 ANKS1A EPHB1	3.39e-03	106	177	5	1.10.150.50
Domain	Ankyrin_rpt	TRPA1 ANK2 TRPC4 ANKS1B CASKIN1 NFKB2 ANKRD36 ANKS1A	3.59e-03	262	177	8	IPR002110
Domain	Death	ANK2 RIPK1 NFKB2	3.70e-03	33	177	3	PF00531
Domain	SLC26A	SLC26A1 SLC26A6	3.82e-03	10	177	2	PS01130
Domain	ZU5	ANK2 TJP1	3.82e-03	10	177	2	PS51145
Domain	Ank_2	TRPA1 ANK2 ANKS1B CASKIN1 NFKB2 ANKRD36 ANKS1A	4.48e-03	215	177	7	PF12796
Domain	Ion_trans_dom	TRPA1 TRPC4 RYR3 SCN7A CNGA1	4.62e-03	114	177	5	IPR005821
Domain	Ion_trans	TRPA1 TRPC4 RYR3 SCN7A CNGA1	4.62e-03	114	177	5	PF00520
Domain	STAS	SLC26A1 SLC26A6	4.64e-03	11	177	2	PS50801
Domain	STAS	SLC26A1 SLC26A6	4.64e-03	11	177	2	PF01740
Domain	SLC26A/SulP_fam	SLC26A1 SLC26A6	4.64e-03	11	177	2	IPR001902
Domain	STAS_dom	SLC26A1 SLC26A6	4.64e-03	11	177	2	IPR002645
Domain	SLC26A/SulP_dom	SLC26A1 SLC26A6	4.64e-03	11	177	2	IPR011547
Pathway	REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING	RPS27A UBA52 UBB UBC BRAF MAPK1	5.11e-09	16	135	6	M514
Pathway	REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING	RPS27A UBA52 UBB UBC BRAF MAPK1	5.11e-09	16	135	6	MM14541
Pathway	REACTOME_ER_QUALITY_CONTROL_COMPARTMENT_ERQC	RPS27A UBA52 UBB UBC	8.05e-09	4	135	4	MM15591
Pathway	REACTOME_TICAM1_RIP1_MEDIATED_IKK_COMPLEX_RECRUITMENT	RIPK1 RPS27A UBA52 UBB UBC IKBKB	1.69e-08	19	135	6	M27020
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPA1 RIPK1 TRPC4 RPS27A RYR3 UBA52 UBB UBC CLCN4 CLCN7	3.51e-08	99	135	10	MM14910
Pathway	KEGG_MEDICUS_REFERENCE_UCHL1_MEDIATED_HYDROLYSIS	RPS27A UBA52 UBB UBC	3.99e-08	5	135	4	M49036
Pathway	REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1	RIPK1 RPS27A UBA52 UBB UBC IKBKB	6.09e-08	23	135	6	M1003
Pathway	REACTOME_RESPONSE_OF_MTB_TO_PHAGOCYTOSIS	RNF213 RPS27A UBA52 UBB UBC MAPK1	6.09e-08	23	135	6	M29824
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPA1 RIPK1 TRPC4 RPS27A RYR3 UBA52 UBB UBC CLCN4 CLCN7	6.77e-08	106	135	10	M27200
Pathway	REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES	RPS27A UBA52 UBB UBC IKBKB	9.05e-08	13	135	5	MM14827
Pathway	REACTOME_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL	RPS27A UBA52 UBB UBC IKBKB	9.05e-08	13	135	5	MM14828
Pathway	REACTOME_MAP3K8_TPL2_DEPENDENT_MAPK1_3_ACTIVATION	RPS27A UBA52 UBB UBC IKBKB	9.05e-08	13	135	5	MM15280
Pathway	REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES	RPS27A UBA52 UBB UBC IKBKB	9.05e-08	13	135	5	M14582
Pathway	REACTOME_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL	RPS27A UBA52 UBB UBC IKBKB	9.05e-08	13	135	5	M736
Pathway	REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1	RIPK1 RPS27A UBA52 UBB UBC IKBKB	1.05e-07	25	135	6	MM15646
Pathway	REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION	CDK9 RPS27A UBA52 UBB UBC MAPK1	1.36e-07	26	135	6	MM14878
Pathway	REACTOME_IRAK1_RECRUITS_IKK_COMPLEX	RPS27A UBA52 UBB UBC IKBKB	1.40e-07	14	135	5	M935
Pathway	REACTOME_INFECTION_WITH_MYCOBACTERIUM_TUBERCULOSIS	RNF213 RPS27A UBA52 UBB UBC MAPK1	1.73e-07	27	135	6	M29816
Pathway	REACTOME_IRAK1_RECRUITS_IKK_COMPLEX	RPS27A UBA52 UBB UBC IKBKB	2.08e-07	15	135	5	MM15645
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR3_SIGNALING	RPS27A UBA52 UBB UBC BRAF MAPK1	2.73e-07	29	135	6	M27528
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR3_SIGNALING	RPS27A UBA52 UBB UBC BRAF MAPK1	2.73e-07	29	135	6	MM15253
Pathway	REACTOME_FLT3_SIGNALING_BY_CBL_MUTANTS	RPS27A UBA52 UBB UBC	2.75e-07	7	135	4	M41737
Pathway	REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS	RPS27A UBA52 UBB UBC	2.75e-07	7	135	4	MM15593
Pathway	REACTOME_CALNEXIN_CALRETICULIN_CYCLE	RPS27A UBA52 UBB UBC	2.75e-07	7	135	4	MM15592
Pathway	REACTOME_MODULATION_BY_MTB_OF_HOST_IMMUNE_SYSTEM	RPS27A UBA52 UBB UBC	2.75e-07	7	135	4	M29822
Pathway	REACTOME_MAP3K8_TPL2_DEPENDENT_MAPK1_3_ACTIVATION	RPS27A UBA52 UBB UBC IKBKB	3.00e-07	16	135	5	M27567
Pathway	REACTOME_P75NTR_SIGNALS_VIA_NF_KB	RPS27A UBA52 UBB UBC IKBKB	3.00e-07	16	135	5	M18175
Pathway	REACTOME_P75NTR_SIGNALS_VIA_NF_KB	RPS27A UBA52 UBB UBC IKBKB	3.00e-07	16	135	5	MM14742
Pathway	REACTOME_ONCOGENE_INDUCED_SENESCENCE	RPS27A UBA52 UBB UBC MAPK1	3.00e-07	16	135	5	MM14903
Pathway	REACTOME_DNA_DAMAGE_BYPASS	RPS27A DDB1 UBA52 UBB UBC POLI MAD2L2	3.35e-07	48	135	7	M27698
Pathway	REACTOME_DNA_DAMAGE_BYPASS	RPS27A DDB1 UBA52 UBB UBC POLI MAD2L2	3.35e-07	48	135	7	MM15432
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR4_SIGNALING	RPS27A UBA52 UBB UBC BRAF MAPK1	4.17e-07	31	135	6	M27529
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR4_SIGNALING	RPS27A UBA52 UBB UBC BRAF MAPK1	4.17e-07	31	135	6	MM15254
Pathway	REACTOME_TRANSLESION_SYNTHESIS_BY_POLK	RPS27A UBA52 UBB UBC MAD2L2	4.22e-07	17	135	5	M27537
Pathway	REACTOME_TRANSLESION_SYNTHESIS_BY_POLK	RPS27A UBA52 UBB UBC MAD2L2	4.22e-07	17	135	5	MM15259
Pathway	REACTOME_REGULATION_OF_NF_KAPPA_B_SIGNALING	RPS27A UBA52 UBB UBC IKBKB	4.22e-07	17	135	5	MM15702
Pathway	REACTOME_TOLL_LIKE_RECEPTOR_9_TLR9_CASCADE	RPS27A PIK3R4 UBA52 UBB UBC MAPK14 NFKB2 MAPK1 IKBKB	4.33e-07	99	135	9	MM14660
Pathway	REACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA	RPS27A UBA52 UBB UBC NFKB2 IKBKB	5.10e-07	32	135	6	MM14707
Pathway	REACTOME_REGULATION_OF_NF_KAPPA_B_SIGNALING	RPS27A UBA52 UBB UBC IKBKB	5.80e-07	18	135	5	M45023
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR1_SIGNALING	RPS27A UBA52 UBB UBC BRAF MAPK1	6.18e-07	33	135	6	M27526
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR2_SIGNALING	RPS27A UBA52 UBB UBC BRAF MAPK1	6.18e-07	33	135	6	MM15252
Pathway	REACTOME_TNFR1_INDUCED_NF_KAPPA_B_SIGNALING_PATHWAY	RIPK1 RPS27A UBA52 UBB UBC IKBKB	6.18e-07	33	135	6	M27438
Pathway	REACTOME_TNFR1_INDUCED_NF_KAPPA_B_SIGNALING_PATHWAY	RIPK1 RPS27A UBA52 UBB UBC IKBKB	6.18e-07	33	135	6	MM15180
Pathway	REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA	RPS27A UBA52 UBB UBC NFKB2 IKBKB	6.18e-07	33	135	6	MM14666
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR2_SIGNALING	RPS27A UBA52 UBB UBC BRAF MAPK1	7.44e-07	34	135	6	M27527
Pathway	REACTOME_PTK6_REGULATES_RTKS_AND_THEIR_EFFECTORS_AKT1_AND_DOK1	RPS27A UBA52 UBB UBC	9.77e-07	9	135	4	M27732
Pathway	REACTOME_INLA_MEDIATED_ENTRY_OF_LISTERIA_MONOCYTOGENES_INTO_HOST_CELLS	RPS27A UBA52 UBB UBC	9.77e-07	9	135	4	M27781
Pathway	REACTOME_DOWNREGULATION_OF_ERBB4_SIGNALING	RPS27A UBA52 UBB UBC	9.77e-07	9	135	4	M26930
Pathway	REACTOME_REGULATION_OF_PTEN_LOCALIZATION	RPS27A UBA52 UBB UBC	9.77e-07	9	135	4	M27814
Pathway	REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1	RPS27A UBA52 UBB UBC	9.77e-07	9	135	4	MM14676
Pathway	REACTOME_PREVENTION_OF_PHAGOSOMAL_LYSOSOMAL_FUSION	RPS27A UBA52 UBB UBC	9.77e-07	9	135	4	M29819
Pathway	REACTOME_MYOCLONIC_EPILEPSY_OF_LAFORA	RPS27A UBA52 UBB UBC	9.77e-07	9	135	4	M27276
Pathway	REACTOME_PTK6_REGULATES_RTKS_AND_THEIR_EFFECTORS_AKT1_AND_DOK1	RPS27A UBA52 UBB UBC	9.77e-07	9	135	4	MM15482
Pathway	REACTOME_DOWNREGULATION_OF_ERBB4_SIGNALING	RPS27A UBA52 UBB UBC	9.77e-07	9	135	4	MM14535
Pathway	REACTOME_TOLL_LIKE_RECEPTOR_9_TLR9_CASCADE	RPS27A PIK3R4 UBA52 UBB UBC MAPK14 NFKB2 MAPK1 IKBKB	9.84e-07	109	135	9	M27012
Pathway	REACTOME_MYD88_INDEPENDENT_TLR4_CASCADE	RIPK1 RPS27A UBA52 UBB UBC MAPK14 NFKB2 MAPK1 IKBKB	9.84e-07	109	135	9	M29565
Pathway	REACTOME_DECTIN_1_MEDIATED_NONCANONICAL_NF_KB_SIGNALING	PSMD3 RPS27A UBA52 UBB UBC PSME4 NFKB2	9.91e-07	56	135	7	MM15203
Pathway	REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS	RPS27A UBA52 UBB UBC MAPK14 NFKB2 IKBKB	9.91e-07	56	135	7	M1074
Pathway	REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION	RPS27A FZD6 UBA52 UBB UBC	1.03e-06	20	135	5	MM15155
Pathway	REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION	CDK9 RPS27A UBA52 UBB UBC MAPK1	1.06e-06	36	135	6	M633
Pathway	REACTOME_NOD1_2_SIGNALING_PATHWAY	RPS27A UBA52 UBB UBC MAPK14 IKBKB	1.06e-06	36	135	6	M1059
Pathway	REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE	RPS27A UBA52 UBB UBC MAPK14 MAPK1	1.26e-06	37	135	6	MM14899
Pathway	REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION	RPS27A FZD6 UBA52 UBB UBC	1.35e-06	21	135	5	M27401
Pathway	REACTOME_INTERLEUKIN_17_SIGNALING	RPS27A UBA52 UBB UBC MAPK14 MAPK1 IKBKB	1.42e-06	59	135	7	MM15128
Pathway	REACTOME_MYD88_MAL_TIRAP_CASCADE_INITIATED_ON_PLASMA_MEMBRANE	RPS27A UBA52 UBB UBC MAPK14 NFKB2 MAPK1 IKBKB	1.49e-06	85	135	8	MM14645
Pathway	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	RPS27A UBA52 UBB UBC	1.62e-06	10	135	4	MM14849
Pathway	REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX	RPS27A UBA52 UBB UBC	1.62e-06	10	135	4	MM15647
Pathway	REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX	RPS27A UBA52 UBB UBC	1.62e-06	10	135	4	M27925
Pathway	REACTOME_REGULATION_OF_PTEN_LOCALIZATION	RPS27A UBA52 UBB UBC	1.62e-06	10	135	4	MM15539
Pathway	REACTOME_CHAPERONE_MEDIATED_AUTOPHAGY	HDAC6 RPS27A UBA52 UBB UBC	1.73e-06	22	135	5	M27937
Pathway	REACTOME_SIGNALING_BY_FGFR3	RPS27A UBA52 UBB UBC BRAF MAPK1	1.74e-06	39	135	6	MM15257
Pathway	REACTOME_TRANSLESION_SYNTHESIS_BY_Y_FAMILY_DNA_POLYMERASES_BYPASSES_LESIONS_ON_DNA_TEMPLATE	RPS27A UBA52 UBB UBC POLI MAD2L2	1.74e-06	39	135	6	MM14475
Pathway	REACTOME_TRANSLESION_SYNTHESIS_BY_Y_FAMILY_DNA_POLYMERASES_BYPASSES_LESIONS_ON_DNA_TEMPLATE	RPS27A UBA52 UBB UBC POLI MAD2L2	1.74e-06	39	135	6	M26897
Pathway	REACTOME_TAK1_DEPENDENT_IKK_AND_NF_KAPPA_B_ACTIVATION	RPS27A UBA52 UBB UBC NFKB2 IKBKB	1.74e-06	39	135	6	MM15116
Pathway	REACTOME_DECTIN_1_MEDIATED_NONCANONICAL_NF_KB_SIGNALING	PSMD3 RPS27A UBA52 UBB UBC PSME4 NFKB2	2.00e-06	62	135	7	M27465
Pathway	REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS	PSMD3 RPS27A UBA52 UBB UBC PSME4 IKBKB	2.00e-06	62	135	7	MM14514
Pathway	REACTOME_SIGNALING_BY_FGFR3	RPS27A UBA52 UBB UBC BRAF MAPK1	2.03e-06	40	135	6	M27532
Pathway	REACTOME_SIGNALING_BY_FGFR4	RPS27A UBA52 UBB UBC BRAF MAPK1	2.03e-06	40	135	6	MM15258
Pathway	REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION	RPS27A UBA52 UBB UBC MAPK14	2.19e-06	23	135	5	M17243
Pathway	REACTOME_TOLL_LIKE_RECEPTOR_CASCADES	RIPK1 RPS27A PIK3R4 UBA52 UBB UBC MAPK14 NFKB2 MAPK1 IKBKB	2.35e-06	155	135	10	MM14665
Pathway	REACTOME_SIGNALING_BY_FGFR4	RPS27A UBA52 UBB UBC BRAF MAPK1	2.36e-06	41	135	6	M27533
Pathway	REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER	CDK9 RPS27A UBA52 UBB UBC MAPK1	2.36e-06	41	135	6	MM14876
Pathway	REACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA	RIPK1 RPS27A UBA52 UBB UBC NFKB2 IKBKB	2.49e-06	64	135	7	M27046
Pathway	REACTOME_REGULATION_OF_BACH1_ACTIVITY	RPS27A UBA52 UBB UBC	2.52e-06	11	135	4	M41833
Pathway	REACTOME_TICAM1_TRAF6_DEPENDENT_INDUCTION_OF_TAK1_COMPLEX	RPS27A UBA52 UBB UBC	2.52e-06	11	135	4	M27885
Pathway	REACTOME_ALPHA_PROTEIN_KINASE_1_SIGNALING_PATHWAY	RPS27A UBA52 UBB UBC	2.52e-06	11	135	4	MM15668
Pathway	REACTOME_PEXOPHAGY	RPS27A UBA52 UBB UBC	2.52e-06	11	135	4	MM15673
Pathway	REACTOME_REGULATION_OF_BACH1_ACTIVITY	RPS27A UBA52 UBB UBC	2.52e-06	11	135	4	MM15686
Pathway	REACTOME_REGULATION_OF_TBK1_IKK_MEDIATED_ACTIVATION_OF_IRF3_IRF7_UPON_TLR3_LIGATION	RPS27A UBA52 UBB UBC	2.52e-06	11	135	4	M48241
Pathway	REACTOME_ALPHA_PROTEIN_KINASE_1_SIGNALING_PATHWAY	RPS27A UBA52 UBB UBC	2.52e-06	11	135	4	M29827
Pathway	REACTOME_PEXOPHAGY	RPS27A UBA52 UBB UBC	2.52e-06	11	135	4	M29846
Pathway	REACTOME_TOLL_LIKE_RECEPTOR_4_TLR4_CASCADE	RIPK1 RPS27A UBA52 UBB UBC MAPK14 NFKB2 MAPK1 IKBKB	2.53e-06	122	135	9	MM14640
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	RPS27A UBA52 UBB UBC BRAF MAPK1	2.73e-06	42	135	6	MM15274
Pathway	REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY	RPS27A UBA52 UBB UBC MAPK1	2.75e-06	24	135	5	MM14877
Pathway	REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION	RPS27A UBA52 UBB UBC MAPK14	2.75e-06	24	135	5	MM15133
Pathway	REACTOME_CLEC7A_DECTIN_1_SIGNALING	PSMD3 RPS27A UBA52 UBB UBC PSME4 NFKB2 IKBKB	2.95e-06	93	135	8	MM15204
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	RPS27A UBA52 UBB UBC BRAF MAPK1	3.14e-06	43	135	6	M27560
Pathway	REACTOME_TAK1_DEPENDENT_IKK_AND_NF_KAPPA_B_ACTIVATION	RPS27A UBA52 UBB UBC NFKB2 IKBKB	3.61e-06	44	135	6	M852
Pathway	REACTOME_JOSEPHIN_DOMAIN_DUBS	RPS27A UBA52 UBB UBC	3.75e-06	12	135	4	M27577
Pathway	REACTOME_JOSEPHIN_DOMAIN_DUBS	RPS27A UBA52 UBB UBC	3.75e-06	12	135	4	MM15288
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	KMT2B RIPK1 CEP162 SYNE1 RNF213 CUL7 ECE1 CLCN7 NFKB2 PLEC IKBKB EPHB1	2.24e-09	214	187	12	22199357
Pubmed	MD-2: the Toll 'gatekeeper' in endotoxin signalling.	RIPK1 RPS27A UBA52 UBB UBC MAPK14 MAPK1 IKBKB	6.69e-09	74	187	8	15276183
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	LRFN1 ANK2 KALRN SYNE1 TRPC4 ANKS1B UPF1 RPS27A DDB1 CASK DST TJP1 MTOR CASKIN1 DZIP3 GOLGA8B MACF1 PRKD1 MAPK1 NOP2 FERMT3 ANKS1A	1.33e-08	963	187	22	28671696
Pubmed	NF-kappaB functions in the nervous system: from development to disease.	RPS27A UBA52 UBB UBC IKBKB	1.77e-08	16	187	5	16997282
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	CDK9 RIPK1 MARK1 PSMD3 RPS27A ANKRD36C CUL7 PIK3R4 PIGQ UBA52 UBB UBC MAPK14 DST BRAF SIK2 PRKD1 ANKRD36 MAPK1 PLEC IKBKB	2.46e-08	910	187	21	36736316
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ZFAT ANK2 MLX KALRN SYNE1 PARP4 UBB UBC DST RNF10 MACF1 ATXN10 MAD2L2 PLEC DNAJB5	9.33e-08	497	187	15	23414517
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	RPS3 RNF213 DHX57 PSMD3 RPS27A CPS1 TJP1 NFKB2 NOP2	9.43e-08	144	187	9	35681168
Pubmed	Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin.	UBA52 UBB UBC POLI	9.99e-08	9	187	4	16763556
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	HDAC6 ANK2 KALRN SYNE1 ANKS1B ABCC5 RPS27A RYR3 CASK PIK3R4 FOCAD UBC DST TJP1 RNF10 PKNOX1 MACF1 PCMTD2 ANKRD36 ATXN10 PLEC ST18 MGAT5B TARBP1	1.24e-07	1285	187	24	35914814
Pubmed	The Ubiquitin Gene Expression Pattern and Sensitivity to UBB and UBC Knockdown Differentiate Primary 23132/87 and Metastatic MKN45 Gastric Cancer Cells.	RPS27A UBB UBC	1.53e-07	3	187	3	32751694
Pubmed	Structure of tetraubiquitin shows how multiubiquitin chains can be formed.	UBA52 UBB UBC	1.53e-07	3	187	3	8107144
Pubmed	Overexpression of three ubiquitin genes in mouse epidermal tumors is associated with enhanced cellular proliferation and stress.	UBA52 UBB UBC	1.53e-07	3	187	3	1321656
Pubmed	ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer.	MAPK14 BRAF MAPK1	1.53e-07	3	187	3	29988110
Pubmed	The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27.	RPS27A UBA52 UBB UBC	1.66e-07	10	187	4	11231585
Pubmed	TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway.	RPS27A UBA52 UBB UBC	1.66e-07	10	187	4	10882101
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ASRGL1 ANK2 KALRN DOCK8 MARK1 RPS3 SYNE1 ANKS1B DHX57 PSMD3 UPF1 DDB1 CASK PIK3R4 DST SLC24A2 TJP1 CASKIN1 OSBPL10 MACF1 MICAL3 MAPK1 PLEC SIPA1L2 DHX29	2.32e-07	1431	187	25	37142655
Pubmed	A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.	HDAC6 RIPK1 PSMD3 FANCD2 UBB MTOR NFKB2 SMARCB1 IKBKB	2.58e-07	162	187	9	14743216
Pubmed	Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase.	PSMD3 RPS27A UBA52 UBB UBC PSME4	5.19e-07	55	187	6	12791267
Pubmed	Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes.	HDAC6 UBB UBC	6.09e-07	4	187	3	12354939
Pubmed	Regulation of follitropin receptor cell surface residency by the ubiquitin-proteasome pathway.	RPS27A UBA52 UBB	6.09e-07	4	187	3	12960054
Pubmed	Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies.	MAPK14 MTOR MAPK1	6.09e-07	4	187	3	10942774
Pubmed	Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes.	MAPK14 MTOR MAPK1	6.09e-07	4	187	3	8083223
Pubmed	The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus.	MAPK14 MTOR MAPK1	6.09e-07	4	187	3	9405468
Pubmed	Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes.	MAPK14 MTOR MAPK1	6.09e-07	4	187	3	9092573
Pubmed	Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades.	MAPK14 BRAF MAPK1	6.09e-07	4	187	3	15632082
Pubmed	Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression.	MAPK14 MTOR MAPK1	6.09e-07	4	187	3	10779345
Pubmed	HDAC6 mediates HIV-1 tat-induced proinflammatory responses by regulating MAPK-NF-kappaB/AP-1 pathways in astrocytes.	HDAC6 MAPK14 MAPK1 IKBKB	1.05e-06	15	187	4	26031809
Pubmed	p75NTR--live or let die.	RPS27A UBA52 UBB UBC	1.40e-06	16	187	4	15721744
Pubmed	Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor.	MAPK14 MTOR MAPK1	1.52e-06	5	187	3	12665511
Pubmed	Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1.	RPS27A UBA52 UBB	1.52e-06	5	187	3	10995389
Pubmed	Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction.	RIPK1 UBC IKBKB	1.52e-06	5	187	3	26740240
Pubmed	Ubiquilin interacts with ubiquitylated proteins and proteasome through its ubiquitin-associated and ubiquitin-like domains.	PSMD3 UBA52 UBC	1.52e-06	5	187	3	15147878
Pubmed	Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint.	PSMD3 RPS27A UBA52 UBB UBC PSME4	1.69e-06	67	187	6	11285280
Pubmed	Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR .	RPS27A UBA52 UBB UBC	1.82e-06	17	187	4	12609980
Pubmed	Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.	UBB MAPK14 MAPK1	3.02e-06	6	187	3	16027724
Pubmed	p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins.	UBA52 UBB UBC	3.02e-06	6	187	3	8702753
Pubmed	The SAM domains of Anks family proteins are critically involved in modulating the degradation of EphA receptors.	ANKS1B UBC ANKS1A	3.02e-06	6	187	3	20100865
Pubmed	Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.	CDK9 MARK1 MAPK14 BRAF MARK4 MAPK1	4.15e-06	78	187	6	17192257
Pubmed	Functional proteomics mapping of a human signaling pathway.	KMT2B DOCK8 RANBP6 RPS27A DDB1 CASK PIGQ UBA52 UBB UBC DST POLI MACF1 PLEC	4.35e-06	591	187	14	15231748
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK9 CEP162 PIK3R4 DST BRAF TJP1 MTOR MARK4 RNF10 SIK2 OSBPL10 KIF14 MACF1 PLEC SIPA1L2 EDRF1 ANKS1A	4.63e-06	861	187	17	36931259
Pubmed	Salvianolic acid B protects human endothelial progenitor cells against oxidative stress-mediated dysfunction by modulating Akt/mTOR/4EBP1, p38 MAPK/ATF2, and ERK1/2 signaling pathways.	MAPK14 MTOR MAPK1	5.27e-06	7	187	3	24780446
Pubmed	Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity.	NFKB2 MAPK1 IKBKB	5.27e-06	7	187	3	28689659
Pubmed	In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of mitogen-activated protein kinases, IkappaB kinases, and interferon regulatory factor 3 and to the release of beta interferon.	MAPK14 MAPK1 IKBKB	5.27e-06	7	187	3	17182689
Pubmed	Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.	PSMD3 RPS27A UBA52 UBB PSME4	8.19e-06	51	187	5	28292943
Pubmed	Direct, noncatalytic mechanism of IKK inhibition by A20.	RIPK1 UBC IKBKB	8.40e-06	8	187	3	22099304
Pubmed	Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected].	MAPK14 NFKB2 IKBKB	8.40e-06	8	187	3	20231695
Pubmed	Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells.	MAPK14 MTOR MAPK1	8.40e-06	8	187	3	12105188
Pubmed	An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein.	RPS27A UBB UBC	8.40e-06	8	187	3	14755250
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	RPS3 SYNE1 RNF213 RPS27A DST PRKD1 ANKRD36 PLEC	8.44e-06	187	187	8	26460568
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CDK9 LRFN1 EPPK1 KMT2B KALRN ECE1 FOCAD DST PSME4 CLCN7 MTOR CASKIN1 NFKB2 MARK4 PPA2 MICAL3 PLEC SIPA1L2 IQGAP3	9.03e-06	1105	187	19	35748872
Pubmed	SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.	LRFN1 CASK MAPK14 MAPK1	9.37e-06	25	187	4	27480238
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	MARK1 TMEM115 ABCC5 RPS27A SSR1 ECE1 CEMIP2 STXBP3 BRAF CLCN7 TBC1D10A MACF1	9.57e-06	467	187	12	30194290
Pubmed	Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication.	RPS27A UBA52 UBB UBC	1.10e-05	26	187	4	11931757
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	INTU ANK2 SYNE1 DNAH2 ANKS1B ABCC5 DHX57 PSMD3 RPS27A ECE1 ADAMTS12 UBA52 UBB UBC DST CLCN4 PHF20L1 TJP1 MACF1 PADI6 PLEC SIPA1L2	1.13e-05	1442	187	22	35575683
Pubmed	HIV Tat induces expression of ICAM-1 in HUVECs: implications for miR-221/-222 in HIV-associated cardiomyopathy.	MAPK14 MAPK1 IKBKB	1.25e-05	9	187	3	23555914
Pubmed	Rac/ROS-related protein kinase C and phosphatidylinositol-3-kinase signaling are involved in a negative regulating cascade in B cell activation by antibody-mediated cross-linking of MHC class II molecules.	MAPK14 NFKB2 MAPK1	1.25e-05	9	187	3	19939451
Pubmed	Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO.	RIPK1 UBC IKBKB	1.25e-05	9	187	3	16603398
Pubmed	Molecular chaperone Hsp90 regulates REV1-mediated mutagenesis.	HDAC6 UBC MAD2L2	1.25e-05	9	187	3	21690293
Pubmed	Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation.	MAPK14 MTOR MAPK1	1.25e-05	9	187	3	11279232
Pubmed	A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage.	RIPK1 MAPK14 IKBKB	1.25e-05	9	187	3	21606198
Pubmed	Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.	UBR1 DDB1 UBR3	1.25e-05	9	187	3	17855541
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	EPPK1 RPS3 PSMD3 PRAMEF12 RPS27A SSR1 DDB1 UBB PSME4 PCMTD2 ATXN10 PLEC IQGAP3	1.29e-05	564	187	13	21565611
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ANK2 ABCC5 CEMIP2 CASK FZD6 STXBP3 BRAF CLCN7 TBC1D10A MTOR OSBPL10 MICAL3 SLC26A6	1.41e-05	569	187	13	30639242
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	EPPK1 HDAC6 RPS3 SYNE1 RNF213 PSMD3 RPS27A UBA52 UBB UBC DST KIF14 MACF1 MAPK1 PLEC NOP2	1.47e-05	844	187	16	25963833
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TMEM115 DNAH2 RANBP6 UPF1 SSR1 CMSS1 FANCD2 FZD6 UBC STXBP3 MTOR UTP20 SLC47A1 ATXN10 MAPK1 TARBP1 IQGAP3	1.48e-05	942	187	17	31073040
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	IFT57 CEP162 RNF213 PSMD3 CUL7 CEMIP2 CASK FANCD2 MAPK14 STXBP3 CLCN7 TJP1 TMF1 KIF14 UBR3 MICAL3 ATXN10 MAPK1	1.62e-05	1049	187	18	27880917
Pubmed	Mammalian Cdh1/Fzr mediates its own degradation.	PSMD3 RPS27A UBA52 UBB UBC	1.69e-05	59	187	5	15029244
Pubmed	RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.	UPF1 UBC SMARCB1 PLEC	1.73e-05	29	187	4	36800290
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	ECM2 DHX57 PSMD3 CUL7 CMSS1 CASK SIK2 KIF14 MACF1 PLEC SIPA1L2 DHX29	1.74e-05	496	187	12	31343991
Pubmed	The trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sites.	RPS27A UBB UBC	1.79e-05	10	187	3	15143060
Pubmed	HSJ1 is a neuronal shuttling factor for the sorting of chaperone clients to the proteasome.	RPS27A UBA52 UBC	1.79e-05	10	187	3	15936278
Pubmed	Adult mice expressing a Braf Q241R mutation on an ICR/CD-1 background exhibit a cardio-facio-cutaneous syndrome phenotype.	MAPK14 BRAF MAPK1	1.79e-05	10	187	3	26472072
Pubmed	Mechanism underlying IκB kinase activation mediated by the linear ubiquitin chain assembly complex.	RIPK1 UBC IKBKB	1.79e-05	10	187	3	24469399
Pubmed	CFAP61 is required for sperm flagellum formation and male fertility in human and mouse.	ODAD2 ROPN1B ROPN1	1.79e-05	10	187	3	34792097
Pubmed	A cohesin-RAD21 interactome.	CDK9 RPS3 RPS27A CPS1 DDB1 FOCAD UBA52 UBC	1.83e-05	208	187	8	22145905
Pubmed	Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).	KALRN RPS27A UBA52 UBB UBC	1.83e-05	60	187	5	12787561
Pubmed	Defining the membrane proteome of NK cells.	CDK9 DOCK8 RPS3 CYP20A1 RNF213 PSMD3 NUF2 RPS27A ECE1 PIK3R4 PARP4 PIGA CLCN7 MTOR KIF14 ATXN10 MCTP2 FERMT3 NCKAP1L	1.95e-05	1168	187	19	19946888
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	RPS3 CEP162 TMEM115 ABCC5 RNF213 RPS27A CEMIP2 CASK AP4E1 DST TJP1 OSBPL10 TMF1 PCCA NOP2	2.23e-05	777	187	15	35844135
Pubmed	STK11 is required for the normal program of ciliated cell differentiation in airways.	MARK1 MARK4 SIK2 MAPK1	2.27e-05	31	187	4	31636950
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CDK9 HDAC6 KALRN MARK1 RPS3 SYNE1 DHX57 UPF1 RPS27A SSR1 DDB1 CASK DST TJP1 SMARCB1 MACF1 PLEC SIPA1L2	2.43e-05	1082	187	18	38697112
Pubmed	USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis.	EPPK1 DDB1 PLEC	2.45e-05	11	187	3	31073027
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	ABCA13 RPS27A RYR3 UBA52 UBB UBC DST PCMTD2 PLEC	2.54e-05	284	187	9	29459677
Pubmed	Fasting-induced activation of mitogen-activated protein kinases (ERK/p38) in the mouse hypothalamus.	MAPK14 MAPK1	2.88e-05	2	187	2	14763996
Pubmed	Cloning of human polyubiquitin cDNAs and a ubiquitin-binding assay involving its in vitro translation product.	UBB UBC	2.88e-05	2	187	2	9644242
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	2.88e-05	2	187	2	11002341
Pubmed	Resequencing and association analysis of the KALRN and EPHB1 genes and their contribution to schizophrenia susceptibility.	KALRN EPHB1	2.88e-05	2	187	2	21041834
Pubmed	Oncogenic B-Raf signaling in melanoma cells controls a network of microRNAs with combinatorial functions.	BRAF MAPK1	2.88e-05	2	187	2	22751131
Pubmed	Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture.	TRPC4 TJP1	2.88e-05	2	187	2	15540229
Pubmed	Hybrid troponin reconstituted from vertebrate and arthropod subunits.	UBB UBC	2.88e-05	2	187	2	124018
Pubmed	Simultaneous Disruption of Both Polyubiquitin Genes Affects Proteasome Function and Decreases Cellular Proliferation.	UBB UBC	2.88e-05	2	187	2	32705536
Pubmed	Lack of effect of the SLC47A1 and SLC47A2 gene polymorphisms on the glycemic response to metformin in type 2 diabetes mellitus patients.	SLC47A2 SLC47A1	2.88e-05	2	187	2	30433870
Pubmed	Virus-induced inhibition of CD1d1-mediated antigen presentation: reciprocal regulation by p38 and ERK.	MAPK14 MAPK1	2.88e-05	2	187	2	16177070
Pubmed	Structure of a new crystal form of tetraubiquitin.	UBB UBC	2.88e-05	2	187	2	11173499
Pubmed	Exogenous ATP modulates PGE2 release in macrophages through sustained phosphorylation of CDK9 and p38 MAPK.	CDK9 MAPK14	2.88e-05	2	187	2	33438260
Pubmed	Murine polyubiquitin mRNA sequence.	RPS27A UBB	2.88e-05	2	187	2	2159627
Pubmed	Inherent low Erk and p38 activity reduce Fas Ligand expression and degranulation in T helper 17 cells leading to activation induced cell death resistance.	MAPK14 MAPK1	2.88e-05	2	187	2	27486885
Pubmed	Nucleotide sequence analysis of a cDNA encoding human ubiquitin reveals that ubiquitin is synthesized as a precursor.	RPS27A UBB	2.88e-05	2	187	2	2581967
Pubmed	Kalirin: a novel genetic risk factor for ischemic stroke.	KALRN ROPN1	2.88e-05	2	187	2	20107840
Pubmed	Impact of Experimental Conditions on the Evaluation of Interactions between Multidrug and Toxin Extrusion Proteins and Candidate Drugs.	SLC47A2 SLC47A1	2.88e-05	2	187	2	27271370
Pubmed	Involvement of p38 MAPK in Leydig cell aging and age-related decline in testosterone.	MAPK14 MAPK1	2.88e-05	2	187	2	36950685
Interaction	RHOF interactions	EPPK1 HDAC6 DOCK8 MARK1 ABCC5 SSR1 CEMIP2 CASK UBB STXBP3 CLCN7 TJP1 MTOR KIF14 MACF1 UTP20 ATXN10 MAD2L2 IQGAP3 SLC26A6	1.42e-06	673	173	20	int:RHOF
Interaction	RAC1 interactions	CYP1B1 HDAC6 KALRN DOCK8 ABCC5 RPS27A SSR1 CEMIP2 CASK FANCD2 FZD6 UBB UBC DST STXBP3 CLCN7 MTOR OSBPL10 KIF14 MACF1 UTP20 MICAL3 IQGAP3 SLC26A6 ANKS1A	4.46e-06	1063	173	25	int:RAC1
Interaction	MMEL1 interactions	RPS27A UBA52 UBB	6.14e-06	5	173	3	int:MMEL1
Interaction	PCNT interactions	KALRN CEP162 SYNE1 UBC DST OSBPL10 KIF14 MACF1 PLEC ST18 ROPN1	7.82e-06	241	173	11	int:PCNT
Interaction	MAP3K3 interactions	RIPK1 RPS27A CUL7 UBA52 UBB MTOR IKBKB	7.90e-06	84	173	7	int:MAP3K3
Interaction	GJA1 interactions	EPHB3 DPEP1 KALRN MARK1 RPS3 TMEM115 CEMIP2 CASK PIK3R4 AP4E1 UBA52 DST TJP1 TMF1 MACF1 MAPK1 SIPA1L2	1.18e-05	583	173	17	int:GJA1
Interaction	ATP1A1 interactions	CDK9 PDSS2 HDAC6 RPS3 RNF213 DHX57 PSMD3 RPS27A CUL7 CPS1 FANCD2 TJP1 NFKB2 KIF14 MAPK1 NOP2	3.78e-05	575	173	16	int:ATP1A1
Interaction	CEP250 interactions	EPPK1 RPS3 RPS27A CUL7 DDB1 UBA52 UBB DST SIK2 SIPA1L2 NOP2	3.95e-05	287	173	11	int:CEP250
Interaction	DSCR9 interactions	HDAC6 KALRN SYNE1 PIK3R4 DST RNF10 MACF1 ATXN10	4.06e-05	147	173	8	int:DSCR9
Interaction	CHEK1 interactions	CDK9 LRFN1 HDAC6 RPS27A DDB1 FANCD2 UBB MTOR DZIP3 MAPK1	5.28e-05	245	173	10	int:CHEK1
Interaction	SYNGAP1 interactions	ASRGL1 ANK2 KALRN ANKS1B MTOR PPA2 MAPK1 SIPA1L2 DHX29 MGAT5B ANKS1A	7.25e-05	307	173	11	int:SYNGAP1
Interaction	GNB1 interactions	HDAC6 KALRN RNF213 PSMD3 FANCD2 UBC MTOR KIF14 PRKD1 ATXN10 MAD2L2	7.25e-05	307	173	11	int:GNB1
Interaction	RAC2 interactions	CYP1B1 ABCC5 SSR1 CEMIP2 CASK FANCD2 FZD6 DST STXBP3 CLCN7 MTOR OSBPL10 TMF1 KIF14 MACF1 UTP20 MCTP2	7.28e-05	674	173	17	int:RAC2
Interaction	TNFSF13B interactions	RANBP6 FANCD2 PIGQ MTOR NFKB2 KIF14 MAP3K15	7.60e-05	119	173	7	int:TNFSF13B
Interaction	H2BC13 interactions	CDK9 HDAC6 RPS27A FANCD2 UBA52 UBB DST PHF20L1 KIF14	8.66e-05	210	173	9	int:H2BC13
Interaction	TNFRSF1A interactions	RIPK1 TRPC4 FANCD2 UBB UBC KIF14 UTP20 MAPK1 IKBKB	8.98e-05	211	173	9	int:TNFRSF1A
Interaction	USP5 interactions	UBR1 RPS27A CUL7 FANCD2 UBA52 UBB UBC SMARCB1 IKBKB	9.65e-05	213	173	9	int:USP5
Interaction	GNB3 interactions	DDB1 CXCR5 MTOR KIF14 MAPK1	9.90e-05	54	173	5	int:GNB3
Interaction	ELK1 interactions	CDK9 SSR1 DDB1 FANCD2 MAPK14 MAPK1 MAD2L2	1.04e-04	125	173	7	int:ELK1
Interaction	POLI interactions	UBA52 UBB UBC POLI	1.05e-04	29	173	4	int:POLI
Interaction	RNF11 interactions	RIPK1 PSMD3 RPS27A UBA52 UBB POLI DZIP3 IKBKB	1.08e-04	169	173	8	int:RNF11
Interaction	H2BC12 interactions	HDAC6 RPS27A FANCD2 ADAMTS12 PARP4 UBA52 UBB DST KIF14 ANKRD36 NOP2	1.11e-04	322	173	11	int:H2BC12
Interaction	KRT8 interactions	CDK9 EPPK1 HDAC6 IFT57 CEP162 NUF2 FANCD2 MAPK14 TJP1 KIF14 MAPK1 PLEC SIPA1L2	1.17e-04	441	173	13	int:KRT8
Interaction	CEP104 interactions	CEP162 TOGARAM1 UPF1 AP4E1 TJP1 KIF14	1.18e-04	89	173	6	int:CEP104
Interaction	UBXN6 interactions	RIPK1 RPS3 ODAD2 CUL7 UBC DST OSBPL10 IQGAP3 EDRF1 TANGO6 ANKS1A	1.20e-04	325	173	11	int:UBXN6
Interaction	MTDH interactions	KMT2B RIPK1 CEP162 SYNE1 RNF213 SSR1 CUL7 ECE1 CLCN7 NFKB2 PLEC IKBKB NOP2 EPHB1	1.22e-04	505	173	14	int:MTDH
Interaction	PFN1 interactions	CDK9 HDAC6 ANK2 DOCK8 UPF1 CUL7 FANCD2 UBB TJP1 TMF1 KIF14 MACF1 MICAL3 SIPA1L2	1.32e-04	509	173	14	int:PFN1
Interaction	C6orf141 interactions	NUF2 RPS27A PLEC SIPA1L2 EDRF1 TANGO6	1.42e-04	92	173	6	int:C6orf141
Interaction	CDC5L interactions	CDK9 EPPK1 KALRN DOCK8 RPS3 SYNE1 PSMD3 NUF2 UPF1 CUL7 DDB1 FANCD2 PARP4 DST DZIP3 KIF14 MACF1 PLEC NOP2	1.44e-04	855	173	19	int:CDC5L
Interaction	GPHN interactions	TCF4 ASRGL1 RPS27A UBC TJP1 MTOR PLEC	1.60e-04	134	173	7	int:GPHN
Interaction	LOC102724334 interactions	RPS27A ADAMTS12 UBA52 UBB KIF14 TARBP1 FERMT3	1.60e-04	134	173	7	int:LOC102724334
Interaction	NTAN1 interactions	UBR1 RIPK1 MGAT5B	1.67e-04	13	173	3	int:NTAN1
Interaction	YWHAE interactions	HDAC6 MLX DOCK8 MARK1 RPS3 PSMD3 CUL7 DDB1 CASK FANCD2 PIK3R4 MAPK14 DST STXBP3 BRAF MTOR MARK4 SIK2 KIF14 MACF1 PRKD1 MAP3K15 SIPA1L2 ANKS1A	1.91e-04	1256	173	24	int:YWHAE
Interaction	YME1L1 interactions	INTU NAAA RANBP6 FANCD2 AP4E1 SMARCB1 KIF14 MAD2L2	1.95e-04	184	173	8	int:YME1L1
Interaction	YWHAH interactions	CDK9 EPPK1 MARK1 CEP162 FANCD2 PIK3R4 DST BRAF TJP1 MTOR MARK4 RNF10 SIK2 OSBPL10 KIF14 MACF1 PRKD1 MAP3K15 PLEC SIPA1L2 EDRF1 ANKS1A	1.97e-04	1102	173	22	int:YWHAH
GeneFamily	EF-hand domain containing\|Plakins	EPPK1 DST MACF1 PLEC	1.86e-07	8	132	4	939
GeneFamily	Ankyrin repeat domain containing	TRPA1 ANK2 TRPC4 ANKS1B ANKRD36C CASKIN1 NFKB2 ANKRD36 ANKS1A	7.23e-05	242	132	9	403
GeneFamily	Glycosyl transferases group 1 domain containing\|Phosphatidylinositol glycan anchor biosynthesis	PIGB PIGQ PIGA	4.59e-04	21	132	3	680
GeneFamily	Sterile alpha motif domain containing	EPHB3 ANKS1B CASKIN1 ANKS1A EPHB1	4.64e-04	88	132	5	760
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR1 UBR3	1.08e-03	7	132	2	785
GeneFamily	Chloride voltage-gated channels	CLCN4 CLCN7	2.29e-03	10	132	2	302
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	TRPC4 ADAMTS12 LRRN3 GALNT17 DST SCN7A MACF1 PRKD1 MCTP2	1.22e-07	193	185	9	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 RNF213 ANKRD36C NPIPB5 BRAF GOLGA8B MACF1 ANKRD36 MCTP2	1.59e-07	199	185	9	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RIPK1 RANBP6 CMSS1 ECE1 CEMIP2 FZD6 POLI MAD2L2	6.65e-07	173	185	8	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 ZFAT ANKS1B SLC47A2 KCNJ15 PAH DIO1 SLC47A1	6.65e-07	173	185	8	8888434641ea554a9b62c436e87920378eef29cd
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	PIGB KALRN RNF213 NPIPB3 NPIPB5 CEMIP2 DST SIK2	7.58e-07	176	185	8	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	PIGB KALRN RNF213 NPIPB3 NPIPB5 CEMIP2 DST SIK2	7.91e-07	177	185	8	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 HDAC6 ANK2 SLC47A2 KCNJ15 PAH SLC47A1 SLC26A6	1.02e-06	183	185	8	facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN ABCA13 ODAD2 CPS1 RYR3 SLC24A2 ST18 DNAH9	1.06e-06	184	185	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN ABCA13 ODAD2 CPS1 RYR3 SLC24A2 ST18 DNAH9	1.06e-06	184	185	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN ABCA13 ODAD2 CPS1 RYR3 SLC24A2 ST18 DNAH9	1.06e-06	184	185	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 DOCK8 SLC47A2 KCNJ15 PAH OSBPL10 SLC47A1 MICAL3	1.20e-06	187	185	8	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	TCF4 ADAMTS2 MARK1 ECM2 ADAMTS12 GALNT17 DST SCN7A	1.20e-06	187	185	8	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	ADAMTS2 TRPC4 ADAMTS12 GALNT17 DST SCN7A MACF1 PRKD1	1.20e-06	187	185	8	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANK2 ADAMTS2 ADAMTS12 GALNT17 DST SCN7A MACF1 PRKD1	1.40e-06	191	185	8	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	UBR1 RNF213 ANKRD36C NPIPB5 CEMIP2 MACF1 MCTP2 EDRF1	1.40e-06	191	185	8	9454f642c3621370fa23640b631301346b300950
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANK2 ADAMTS2 ADAMTS12 GALNT17 DST SCN7A MACF1 PRKD1	1.46e-06	192	185	8	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 GPR82 RNF213 ANKRD36C NPIPB5 GOLGA8B MACF1 ANKRD36	1.51e-06	193	185	8	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KALRN SYNE1 ANKS1B FOCAD GALNT17 GOLGA8B ANKRD36 TARBP1	1.70e-06	196	185	8	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TCF4 ADAMTS2 KALRN ADAMTS12 GALNT17 DST SCN7A MACF1	1.70e-06	196	185	8	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KALRN SYNE1 ANKS1B FOCAD GALNT17 GOLGA8B ANKRD36 TARBP1	1.83e-06	198	185	8	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CYP1B1 ANK2 SYNE1 NRIP3 ADAMTS12 DST MACF1 PRKD1	1.98e-06	200	185	8	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CYP1B1 ANK2 SYNE1 NRIP3 ADAMTS12 DST MACF1 PRKD1	1.98e-06	200	185	8	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP10 ABCA13 ANKS1B CPS1 ST18 DNAH9 CNGA1	5.28e-06	162	185	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF4 ECM2 ECE1 FZD6 DST PLEC EPHB1	6.45e-06	167	185	7	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF4 ECM2 ECE1 FZD6 DST PLEC EPHB1	6.45e-06	167	185	7	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF4 ECM2 ECE1 FZD6 DST PLEC EPHB1	6.45e-06	167	185	7	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF4 ECM2 ECE1 FZD6 DST PLEC EPHB1	6.45e-06	167	185	7	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	INTU ABCA13 DNAH2 ODAD2 CFAP54 DZIP3 DNAH9	6.97e-06	169	185	7	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 RNF213 ANKRD36C CEMIP2 BRAF MACF1 ANKRD36	7.53e-06	171	185	7	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPP10 DOCK8 UST GALNT17 KBTBD12 GRIP2 SIPA1L2	9.09e-06	176	185	7	c2c4306476989bc2fb30dab00250ef7915842f13
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 ANK2 SLC47A2 KCNJ15 PAH DIO1 SLC47A1	1.05e-05	180	185	7	f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 ANKS1B SLC47A2 KCNJ15 PAH DIO1 SLC47A1	1.05e-05	180	185	7	1363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	SYNE1 RNF213 ANKRD36C CEMIP2 MACF1 ANKRD36	1.16e-05	121	185	6	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	ICU-NoSEP-Lymphocyte-B-B_memory\|ICU-NoSEP / Disease, Lineage and Cell Type	TCF4 IFT57 RPS3 RPS27A CXCR5 OSBPL10 SMARCB1	1.17e-05	183	185	7	c6d1d0779c46e08d2235b6dd342a7ec25911864c
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	ZFAT ANKS1B SLC47A2 KCNJ15 PAH DIO1 SLC47A1	1.21e-05	184	185	7	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 ANKS1B SLC47A2 KCNJ15 PAH DIO1 SLC47A1	1.30e-05	186	185	7	8287146f0ba415ea04475588117d4668ae00f75c
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DOCK8 RNF213 ANKRD36C NPIPB5 KIF14 MACF1 MCTP2	1.30e-05	186	185	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 ANKS1B SLC47A2 KCNJ15 PAH DIO1 SLC47A1	1.35e-05	187	185	7	1b82920588f9e26ef1db244d452736d75fcfd342
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 ANKS1B SLC47A2 KCNJ15 PAH DIO1 SLC47A1	1.35e-05	187	185	7	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 ANKS1B SLC47A2 KCNJ15 PAH DIO1 SLC47A1	1.35e-05	187	185	7	c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.39e-05	188	185	7	229108e7e3db49e1cfd747d69e338394139d95b3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF781 RNF213 CEMIP2 MACF1 MAPK1 MCTP2 SLC27A5	1.39e-05	188	185	7	f7dc29dfec68236883469e848be5db34f5526d6b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF781 RNF213 CEMIP2 MACF1 MAPK1 MCTP2 SLC27A5	1.39e-05	188	185	7	9abd78970bbe4ed03b59a83da63bbd334712f605
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.39e-05	188	185	7	cd833a125a5279ac32a9a9cb9ecd05ae24bea3a9
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF781 RNF213 CEMIP2 MACF1 MAPK1 MCTP2 SLC27A5	1.39e-05	188	185	7	5ae8ccdd328cf117da1d01ced2c3b7f763a5f1f1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 ANKS1B SLC47A2 KCNJ15 PAH DIO1 SLC47A1	1.39e-05	188	185	7	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.49e-05	190	185	7	95b9334573eefb132daaa9371377ad60232006ae
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Ptgfr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTS2 TRPC4 RYR3 KIF14 DNAH9 ROPN1	1.53e-05	127	185	6	fb58f4b4d3722f4b9a2e4946c0244c5b70dd883b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 SLC47A2 KCNJ15 PAH OSBPL10 SLC47A1 MICAL3	1.55e-05	191	185	7	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.55e-05	191	185	7	b7d17d3ba488378b30f3732f8109f4a7c1673e61
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPEP1 SLC47A2 KCNJ15 PAH OSBPL10 SLC47A1 MICAL3	1.55e-05	191	185	7	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.55e-05	191	185	7	22134a2c1a92208bc1629a620ce73a56502613c2
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	DOCK8 DST PSME4 SIK2 OSBPL10 SLC47A1 ANKS1A	1.55e-05	191	185	7	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_memory\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.60e-05	192	185	7	72f936f03bb9b58c1ccaaf8270c07f5bbf2ac355
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1\|World / Primary Cells by Cluster	TCF4 RPS27A NRIP3 CEMIP2 UBA52 UBB GRIP2	1.60e-05	192	185	7	bcc499f4c7ba2898ecd9c47bf68c92ed359b81ba
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.60e-05	192	185	7	debd471f61cf3606b8e9c246add0be5df601af7f
ToppCell	Healthy-B_naive\|Healthy / disease group, cell group and cell class	TCF4 IFT57 CXCR5 CLEC20A CLCN4 OSBPL10 MICAL3	1.60e-05	192	185	7	5fddf679dcc9c0077d6bfe04c1e602863fb959eb
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_memory\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.60e-05	192	185	7	149ea3f0181f194ccf141583b08af033ef9fc7c1
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.60e-05	192	185	7	314f74dd3c6d94839eed05b9a1a398217ef78029
ToppCell	ILEUM-inflamed-(2)_Memory_B_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TCF4 IFT57 RPS3 RPS27A CXCR5 OSBPL10 SMARCB1	1.60e-05	192	185	7	4f82913e9ae8ab6dd3e8885a0a7f4dca92e318e1
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-B_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TCF4 IFT57 RPS27A CXCR5 OSBPL10 SMARCB1 MICAL3	1.60e-05	192	185	7	0bda96d8f223e8fa9caf935079ab202fc5c812ee
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_memory-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.60e-05	192	185	7	dac61f0b374f6f9476eedce97f341f26c1bc037c
ToppCell	COVID-19_Mild-Lymphoid_B-B_memory\|COVID-19_Mild / Disease group, lineage and cell class	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.60e-05	192	185	7	d27db7669de95bddbea8ccb83e6f10ae7240b1ab
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ADAMTS12 LRRN3 GALNT17 DST SCN7A MACF1 MCTP2	1.60e-05	192	185	7	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	mild_COVID-19-B_memory\|World / disease group, cell group and cell class (v2)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.65e-05	193	185	7	69b70c838328fdc7dbb6b5449fe2811a5389a839
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	ABCA13 DNAH2 ODAD2 CFAP54 AADACL2 DZIP3 DNAH9	1.65e-05	193	185	7	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DOCK8 UBC DST TJP1 TMF1 MACF1	1.65e-05	193	185	7	9c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4\|World / Primary Cells by Cluster	TCF4 RPS27A NRIP3 CEMIP2 DST SMARCB1 GRIP2	1.65e-05	193	185	7	2eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCell	facs-Brain_Myeloid-Hippocampus-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DOCK8 UBC DST TJP1 TMF1 MACF1	1.65e-05	193	185	7	a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DOCK8 UBC DST TJP1 TMF1 MACF1	1.65e-05	193	185	7	b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DOCK8 UBC DST TJP1 TMF1 MACF1	1.65e-05	193	185	7	06b65110db974f4ef90d3511ff34428976a52c9c
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IFT57 CXCR5 CLEC20A CLCN4 OSBPL10 MICAL3	1.65e-05	193	185	7	cf4ba50aa4a00d1ba22fc7626d49a4104377d5d9
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-B_lymphocytic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TCF4 IFT57 RPS27A CXCR5 OSBPL10 SMARCB1 MICAL3	1.65e-05	193	185	7	ddc06227f2580774d9f34729dff912d6a9155f9c
ToppCell	mild_COVID-19-B_memory\|mild_COVID-19 / disease group, cell group and cell class (v2)	TCF4 IFT57 CXCR5 NFKB2 OSBPL10 SMARCB1 MICAL3	1.65e-05	193	185	7	7e6fe70928a50b0a8f12220e572c07c5670d092e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS2 ADAMTS12 GALNT17 DST SCN7A MACF1 PRKD1	1.65e-05	193	185	7	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS2 ADAMTS12 GALNT17 DST SCN7A MACF1 PRKD1	1.65e-05	193	185	7	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	INTU ABCA13 SYNE1 DNAH2 CFAP54 DZIP3 DNAH9	1.71e-05	194	185	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TCF4 KALRN ANKS1B ADAMTS12 DST MACF1 PCCA	1.71e-05	194	185	7	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	RPS3 RPS27A ANKRD36C LRRN3 GOLGA8B MACF1 ANKRD36	1.77e-05	195	185	7	4bdedd924564a260841a9153604026b57487c83d
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	ADAMTS2 ECM2 ADAMTS12 GALNT17 DST SCN7A PRKD1	1.77e-05	195	185	7	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IFT57 ABCA13 DNAH2 ODAD2 CFAP54 DZIP3 DNAH9	1.77e-05	195	185	7	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TCF4 KALRN ANKS1B ADAMTS12 DST MACF1 PCCA	1.77e-05	195	185	7	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IFT57 ABCA13 DNAH2 ODAD2 CFAP54 DZIP3 DNAH9	1.77e-05	195	185	7	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IFT57 ABCA13 DNAH2 ODAD2 CFAP54 DZIP3 DNAH9	1.77e-05	195	185	7	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCF4 IFT57 ANKRD36C CEMIP2 TMF1 GOLGA8B ANKRD36	1.77e-05	195	185	7	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	ABCA13 SYNE1 ODAD2 CFAP54 MACF1 MCTP2 DNAH9	1.83e-05	196	185	7	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	ABCA13 SYNE1 ODAD2 CFAP54 MACF1 MCTP2 DNAH9	1.83e-05	196	185	7	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS2 ECM2 ADAMTS12 LRRN3 DST SCN7A MACF1	1.83e-05	196	185	7	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ECM2 ADAMTS12 LRRN3 GALNT17 DST SCN7A MACF1	1.83e-05	196	185	7	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS2 ECM2 ADAMTS12 LRRN3 DST SCN7A MACF1	1.83e-05	196	185	7	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANK2 ADAMTS2 ADAMTS12 GALNT17 DST SCN7A MACF1	1.83e-05	196	185	7	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CYP1B1 INTU ANK2 SYNE1 NRIP3 DST MACF1	1.89e-05	197	185	7	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 RNF213 ANKRD36C NPIPB5 GOLGA8B MACF1 ANKRD36	1.89e-05	197	185	7	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 RNF213 ANKRD36C NPIPB5 GOLGA8B ANKRD36 MCTP2	1.89e-05	197	185	7	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 ADAMTS2 ADAMTS12 LRRN3 DST SCN7A MACF1	1.89e-05	197	185	7	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	TCF4 ADAMTS12 GALNT17 SCN7A MACF1 PRKD1 MCTP2	1.89e-05	197	185	7	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	ANK2 ADAMTS2 ADAMTS12 GALNT17 DST SCN7A PRKD1	1.95e-05	198	185	7	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TCF4 ADAMTS2 KALRN ADAMTS12 GALNT17 DST SCN7A	1.95e-05	198	185	7	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS2 ECM2 ADAMTS12 LRRN3 DST SCN7A MACF1	1.95e-05	198	185	7	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TCF4 KALRN ADAMTS12 GALNT17 DST SCN7A MACF1	1.95e-05	198	185	7	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 RNF213 ANKRD36C DST MACF1	1.15e-04	50	104	5	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Drug	Velcade (bortezomib	HDAC6 ADAMTS2 PSMD3 RPS27A UBA52 UBB UBC MAPK14 PSME4 BRAF MTOR NFKB2 MAPK1 IKBKB	1.90e-06	374	181	14	CID000093860
Drug	Shikoccin	UBA52 UBB UBC	1.97e-06	4	181	3	CID000327536
Drug	Ula 1	UBA52 UBB UBC	1.97e-06	4	181	3	CID003047135
Drug	uranium-bromide	UBA52 UBB UBC	1.97e-06	4	181	3	CID000083507
Drug	2c5o	CDK9 HDAC6 RPS27A UBA52 UBB UBC MAPK14 CASKIN1 NFKB2 PRKD1 PCMTD2 IKBKB	3.08e-06	284	181	12	CID000447956
Drug	Prednicarbate [73771-04-7]; Down 200; 8.2uM; PC3; HT_HG-U133A	EPHB3 CYP1B1 CUL7 CEMIP2 MAPK14 CLCN4 NFKB2 SMARCB1 IKBKB SLC26A6	3.50e-06	193	181	10	5119_DN
Drug	Papet	UBA52 UBB UBC	4.88e-06	5	181	3	CID005310950
Drug	4-(oxyacetyl)phenoxyacetic acid	UBA52 UBB UBC	4.88e-06	5	181	3	CID000170173
Drug	L2-G	UBA52 UBB UBC	1.69e-05	7	181	3	CID009549184
Drug	Cu L	CUL7 DDB1 UBA52 UBB UBC	1.79e-05	41	181	5	CID000444966
Drug	AC1L1HZ7	RPS27A UBA52 UBB UBC MAPK1	2.01e-05	42	181	5	CID000004355
Drug	18-crown-6	MLX SYNE1 POLI PCCA	2.53e-05	22	181	4	CID000028557
Drug	STOCK1N-35874; Up 200; 14uM; PC3; HT_HG-U133A	CYP1B1 KMT2B MLX CYP20A1 CASK BRAF PKNOX1 MAPK1 IKBKB	2.73e-05	195	181	9	6583_UP
Drug	morphine hydrochloride	ASRGL1 TRPA1 PIK3R4 CXCR5 UBA52 UBB UBC MAPK14 NFKB2 PAH UGT2B10 CCR8 GRIP2 MAPK1	3.26e-05	481	181	14	CID000004253
Drug	Zlllal	CDK9 CYP1B1 PSMD3 RPS27A UBA52 UBB UBC MAPK14 PSME4 MTOR NFKB2 PKNOX1 SMARCB1 PRKD1 MAPK1 IKBKB	3.32e-05	613	181	16	CID000107707
Drug	M6 - t	UBA52 UBB UBC	4.01e-05	9	181	3	CID004477692
Drug	NSC106399	HDAC6 UBA52 UBB UBC PRKD1	5.25e-05	51	181	5	CID000002887
Drug	AC1L9LT0	ANK2 RIPK1 CASK UBA52 UBB UBC TJP1	5.84e-05	123	181	7	CID000448294
Drug	cinchonidine	SLC47A2 SLC47A1	6.29e-05	2	181	2	ctd:C041622
Drug	ethohexadiol	SLC47A2 SLC47A1	6.29e-05	2	181	2	ctd:C004917
Drug	Sulfamerazine	SLC47A2 SLC47A1	6.29e-05	2	181	2	ctd:D013416
Drug	triethylmethylammonium	SLC47A2 SLC47A1	6.29e-05	2	181	2	ctd:C043900
Drug	UCH-L3 inhibitor	UBB UBC	6.29e-05	2	181	2	CID002729042
Drug	4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE	MAPK14 MAPK1	6.29e-05	2	181	2	DB08521
Drug	Midodrine	SLC47A2 SLC47A1	6.29e-05	2	181	2	ctd:D008879
Drug	SB220025	MAPK14 MAPK1	6.29e-05	2	181	2	DB04338
Drug	Nialamide	SLC47A2 SLC47A1	6.29e-05	2	181	2	ctd:D009526
Drug	cyclopentenone	UBA52 UBB UBC MAPK14 NFKB2 TMF1 IKBKB	6.81e-05	126	181	7	CID000013588
Drug	AC-759	UBR1 ASRGL1 ABCC5 UBA52 UBB UBC	7.34e-05	88	181	6	CID000005396
Disease	neurodegenerative disease (implicated_via_orthology)	UBR1 MARK1 TRPC4 NFKB2 MARK4 UBR3 PNPLA7	2.56e-05	145	174	7	DOID:1289 (implicated_via_orthology)
Disease	serum metabolite measurement, glycine measurement	CYP21A2 CPS1	3.46e-05	2	174	2	EFO_0005653, EFO_0009767
Disease	5-hydroxymethyl-2-furoylcarnitine measurement	CYP21A2 CPS1	3.46e-05	2	174	2	EFO_0801053
Disease	X-24757 measurement	CYP21A2 CPS1	3.46e-05	2	174	2	EFO_0800905
Disease	cinnamoylglycine measurement	CYP21A2 CPS1	3.46e-05	2	174	2	EFO_0800962
Disease	isovalerylglycine measurement	CYP21A2 CPS1	3.46e-05	2	174	2	EFO_0800025
Disease	N-acetylaspartic acid measurement	CYP21A2 CPS1	3.46e-05	2	174	2	EFO_0801183
Disease	serum metabolite measurement, creatine measurement	CYP21A2 CPS1	3.46e-05	2	174	2	EFO_0005653, EFO_0010472
Disease	NMMA measurement	CYP21A2 CPS1	3.46e-05	2	174	2	EFO_0801206
Disease	X-17367 measurement	CYP21A2 CPS1	3.46e-05	2	174	2	EFO_0800779
Disease	Osteopetrosis Autosomal Dominant Type 2	CLCN7 FERMT3	1.03e-04	3	174	2	C3179239
Disease	butyrylglycine measurement	CYP21A2 CPS1	1.03e-04	3	174	2	EFO_0800208
Disease	monocyte chemotactic protein 3 measurement	CYP21A2 CPS1	1.03e-04	3	174	2	EFO_0008235
Disease	Congenital Osteopetrosis	CLCN7 FERMT3	1.03e-04	3	174	2	C3645711
Disease	X-08988 measurement	CYP21A2 CPS1	1.03e-04	3	174	2	EFO_0021207
Disease	X-25420 measurement	CYP21A2 CPS1	1.03e-04	3	174	2	EFO_0800926
Disease	indolepropionylglycine measurement	CYP21A2 CPS1	1.03e-04	3	174	2	EFO_0800089
Disease	2-methylserine measurement	CYP21A2 CPS1	1.03e-04	3	174	2	EFO_0800087
Disease	tigloylglycine measurement	CYP21A2 CPS1	1.03e-04	3	174	2	EFO_0800121
Disease	glycine measurement, amino acid measurement	CYP21A2 CPS1	2.06e-04	4	174	2	EFO_0005134, EFO_0009767
Disease	gamma-glutamylcitrulline measurement	CYP21A2 CPS1	2.06e-04	4	174	2	EFO_0800690
Disease	Multiple congenital anomalies-hypotonia-seizures syndrome	PIGQ PIGA	2.06e-04	4	174	2	cv:C5191419
Disease	amino acid measurement, citrulline measurement	CYP21A2 CPS1	2.06e-04	4	174	2	EFO_0005134, EFO_0009777
Disease	urinary sodium to creatinine ratio	CYP21A2 CPS1	2.06e-04	4	174	2	EFO_0009883
Disease	isobutyrylglycine measurement	CYP21A2 CPS1	2.06e-04	4	174	2	EFO_0800029
Disease	visual impairment and progressive phthisis bulbi (implicated_via_orthology)	MARK1 MARK4	2.06e-04	4	174	2	DOID:0070356 (implicated_via_orthology)
Disease	X-17325 measurement	CYP21A2 CPS1	2.06e-04	4	174	2	EFO_0800771
Disease	prostate adenocarcinoma (is_implicated_in)	BRAF MAPK1 IKBKB	2.13e-04	20	174	3	DOID:2526 (is_implicated_in)
Disease	propionylglycine measurement	CYP21A2 CPS1	3.42e-04	5	174	2	EFO_0800207
Disease	Osteopetrosis	CLCN7 FERMT3	3.42e-04	5	174	2	C0029454
Disease	2-butenoylglycine measurement	CYP21A2 CPS1	3.42e-04	5	174	2	EFO_0800556
Disease	3-hydroxybutyroylglycine measurement	CYP21A2 CPS1	3.42e-04	5	174	2	EFO_0800568
Disease	lysine measurement, amino acid measurement	CYP21A2 CPS1	3.42e-04	5	174	2	EFO_0005002, EFO_0005134
Disease	L-arginine measurement, amino acid measurement	CYP21A2 CPS1	3.42e-04	5	174	2	EFO_0005134, EFO_0006524
Disease	3-methylglutaconate measurement	CYP21A2 CPS1	5.11e-04	6	174	2	EFO_0800047
Disease	5-methylthioadenosine (MTA) measurement	CYP21A2 CPS1	5.11e-04	6	174	2	EFO_0800130
Disease	2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA) measurement	CYP21A2 CPS1	5.11e-04	6	174	2	EFO_0800111
Disease	urinary potassium to creatinine ratio	CYP21A2 CPS1	5.11e-04	6	174	2	EFO_0009882
Disease	X-16570 measurement	CYP21A2 CPS1	5.11e-04	6	174	2	EFO_0800759
Disease	lifestyle measurement, alcohol consumption measurement	INTU RANBP6 CEMIP2 CFAP54 PRKD1	6.12e-04	115	174	5	EFO_0007878, EFO_0010724
Disease	hexanoylglycine measurement	CYP21A2 CPS1	7.12e-04	7	174	2	EFO_0800233
Disease	gamma-glutamylglycine measurement	CYP21A2 CPS1	7.12e-04	7	174	2	EFO_0800670
Disease	amino acid measurement, threonine measurement	CYP21A2 CPS1	7.12e-04	7	174	2	EFO_0005134, EFO_0009775
Disease	epidermolysis bullosa simplex (is_implicated_in)	DST PLEC	7.12e-04	7	174	2	DOID:4644 (is_implicated_in)
Disease	osteopetrosis (implicated_via_orthology)	CLCN4 CLCN7	7.12e-04	7	174	2	DOID:13533 (implicated_via_orthology)
Disease	peripheral neuropathy	GALNT17 SCN7A	7.12e-04	7	174	2	EFO_0003100
Disease	N-palmitoylglycine measurement	CYP21A2 CPS1	7.12e-04	7	174	2	EFO_0800342
Disease	muscular atrophy (implicated_via_orthology)	MTOR IKBKB	7.12e-04	7	174	2	DOID:767 (implicated_via_orthology)
Disease	glycosyl-N-(2-hydroxynervonoyl)-sphingosine (d18:1/24:1(2OH)) measurement	CYP21A2 CPS1	9.46e-04	8	174	2	EFO_0800533
Disease	carnitine measurement	CYP21A2 CPS1 SLC47A1 PCCA	1.08e-03	76	174	4	EFO_0010469
Disease	cancer (implicated_via_orthology)	RANBP6 DST BRAF MTOR MACF1 MAPK1 NOP2	1.10e-03	268	174	7	DOID:162 (implicated_via_orthology)
Disease	colorectal adenocarcinoma (is_implicated_in)	KMT2B BRAF MAPK1	1.15e-03	35	174	3	DOID:0050861 (is_implicated_in)
Disease	1-ribosyl-imidazoleacetate measurement	CYP21A2 CPS1	1.21e-03	9	174	2	EFO_0800034
Disease	2R,3R-dihydroxybutyrate measurement	CYP21A2 CPS1	1.21e-03	9	174	2	EFO_0800314
Disease	X-21467 measurement	CYP21A2 CPS1	1.21e-03	9	174	2	EFO_0020007
Disease	ovarian neoplasm	CYP1B1 HDAC6 BRAF MTOR MAPK1	1.22e-03	134	174	5	C0919267
Disease	Malignant neoplasm of ovary	CYP1B1 HDAC6 BRAF MTOR MAPK1	1.34e-03	137	174	5	C1140680
Disease	Autism Spectrum Disorders	DPP10 LRRN3 PAH IQGAP3	1.63e-03	85	174	4	C1510586
Disease	glutamine measurement, amino acid measurement	CYP21A2 CPS1	1.84e-03	11	174	2	EFO_0005134, EFO_0009768
Disease	3-methylglutarylcarnitine (2) measurement	CYP21A2 CPS1	1.84e-03	11	174	2	EFO_0800074
Disease	stromal cell-derived factor 1 alpha measurement	CYP21A2 ANKS1B CPS1	2.09e-03	43	174	3	EFO_0008293
Disease	renal fibrosis (biomarker_via_orthology)	ECE1 MAPK1	2.19e-03	12	174	2	DOID:0050855 (biomarker_via_orthology)
Disease	red blood cell density measurement	ZFAT KALRN CYP21A2 DNAH2 SSR1 CPS1 FOCAD DST PHF20L1 MARK4 POLI MAPK1 PLEC	2.25e-03	880	174	13	EFO_0007978
Disease	Neurodevelopmental Disorders	TCF4 ANK2 DOCK8 CASK	2.27e-03	93	174	4	C1535926
Disease	social interaction measurement	TCF4 IFT57 RASSF10 PPA2	2.36e-03	94	174	4	EFO_0009592
Disease	fibrinogen measurement, tissue plasminogen activator measurement	CYP21A2 CPS1 PLEC	2.38e-03	45	174	3	EFO_0004623, EFO_0004791
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	CYP21A2 CPS1 PLEC	2.38e-03	45	174	3	EFO_0004623, EFO_0004792
Disease	Gastric Adenocarcinoma	MARK1 MAPK14 EPHB1	2.38e-03	45	174	3	C0278701
Disease	Adenocarcinoma of large intestine	RIPK1 BRAF MARK4 MAP3K15	2.55e-03	96	174	4	C1319315
Disease	glutaroyl carnitine measurement	CYP21A2 CPS1	2.58e-03	13	174	2	EFO_0021005
Disease	cortical surface area measurement	TCF4 INTU CEP162 CYP21A2 CPS1 SLC26A1 FOCAD PIGQ TJP1 MACF1 PRKD1 ATXN10 PCCA MCTP2 TANGO6 ANKS1A EPHB1	2.60e-03	1345	174	17	EFO_0010736
Disease	lymphocyte count	TCF4 ZFAT EPPK1 KALRN CYP21A2 ABCC5 PSMD3 CPS1 FOCAD PSME4 NFKB2 MARK4 PPA2 DZIP3 SLC47A1 MICAL3 PLEC FERMT3	2.63e-03	1464	174	18	EFO_0004587
Disease	upper face morphology measurement	TRPC4 SLC24A2 MACF1 PCCA	2.64e-03	97	174	4	EFO_0010949
Disease	platelet measurement	EPPK1 KALRN DOCK8 CYP21A2 CPS1 MARK4 PLEC	2.75e-03	315	174	7	EFO_0005036
Disease	mean reticulocyte volume	DPEP1 INTU ZFAT SMCO1 DNAH2 PIGQ PHF20L1 MTOR MARK4 PPA2 POLI SLC27A5	2.89e-03	799	174	12	EFO_0010701
Disease	N-acetylglycine measurement	CYP21A2 CPS1	3.00e-03	14	174	2	EFO_0021002
Disease	revision of total hip arthroplasty	ADAMTS12 OSBPL10	3.00e-03	14	174	2	EFO_0020973
Disease	diabetic neuropathy (implicated_via_orthology)	TRPA1 MAPK14	3.00e-03	14	174	2	DOID:9743 (implicated_via_orthology)
Disease	Colorectal Carcinoma	DPEP1 CYP1B1 ANK2 KALRN ABCA13 SYNE1 ABCC5 BRAF PKNOX1 PRKD1 EDRF1	3.12e-03	702	174	11	C0009402
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	CYP21A2 CPS1 MACF1 EPHB1	3.28e-03	103	174	4	EFO_0008595, EFO_0020944
Disease	nose morphology measurement	EPHB3 TCF4 NPIPB11 CMSS1 SLC24A2 UGT2B10 PCCA	3.50e-03	329	174	7	EFO_0007843
Disease	retinal vasculature measurement	TPO LRIT2 TCF4 CYP21A2 CPS1 FZD6 SCN7A SLC47A1 DNAH9	3.72e-03	517	174	9	EFO_0010554
Disease	ureidopropionic acid measurement	CYP21A2 CPS1	3.93e-03	16	174	2	EFO_0010542
Disease	Blood Platelet Disorders	ABCG5 FERMT3	3.93e-03	16	174	2	C0005818
Disease	Early infantile epileptic encephalopathy with suppression bursts	CASK PIGQ	3.93e-03	16	174	2	C0393706
Disease	Metastatic melanoma	MTOR PRKD1 MAP3K15	4.01e-03	54	174	3	C0278883
Disease	hip circumference	ZFAT DPP10 DOCK8 ANKS1B BRAF PRKD1 ATXN10	4.05e-03	338	174	7	EFO_0005093
Disease	Ischemic stroke, fibrinogen measurement	CYP21A2 CPS1 PLEC	4.22e-03	55	174	3	EFO_0004623, HP_0002140
Disease	phenylalanine measurement	CYP21A2 CPS1 PAH	4.22e-03	55	174	3	EFO_0005001
Disease	calcium measurement	DPEP1 CYP21A2 DNAH2 CPS1 ECE1 MARK4 PPA2 KIF14 MACF1 PLEC	4.26e-03	628	174	10	EFO_0004838
Disease	immature granulocyte count	PSMD3 MARK4	4.44e-03	17	174	2	EFO_0803542
Disease	glutarylcarnitine (C5-DC) measurement	CYP21A2 CPS1	4.44e-03	17	174	2	EFO_0800030
Disease	serine measurement, amino acid measurement	CYP21A2 CPS1	4.44e-03	17	174	2	EFO_0005134, EFO_0009774
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	CYP21A2 CPS1 PLEC	4.44e-03	56	174	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	immature platelet fraction	KALRN DOCK8 MARK4 PLEC	4.71e-03	114	174	4	EFO_0009187
Disease	Malignant neoplasm of breast	CYP1B1 ANK2 KALRN SYNE1 TRPC4 PIK3R4 CXCR5 BRAF MTOR KCNJ15 MACF1 UTP20 IKBKB DNAH9	4.72e-03	1074	174	14	C0006142
Disease	urate measurement, spine bone mineral density	PRR35 MARK4 SLC27A5	4.90e-03	58	174	3	EFO_0004531, EFO_0007701
Disease	fibrinogen measurement, factor VII measurement	CYP21A2 CPS1 PLEC	4.90e-03	58	174	3	EFO_0004619, EFO_0004623
Disease	nevus count	CYP1B1 DOCK8	4.97e-03	18	174	2	EFO_0004632
Disease	total blood protein measurement	CYP21A2 CPS1 NPIPB2 CEMIP2 MARK4 PPA2 MACF1 MICAL3	5.35e-03	449	174	8	EFO_0004536

Protein segments in the cluster

Peptide	Gene	Start	Entry
EVGVLRKTRHVNILL	BRAF	501	P15056
EHGIVLTRDVAIKLV	AADACL2	236	Q6P093
QHRIAVVLLDKLQVL	CFAP54	791	Q96N23
GRTVRTEDKILHIVI	DNAJB5	201	O75953
VIGNVLVLVILERHR	CXCR5	66	P32302
HGESILKVNLARLTL	ASRGL1	221	Q7L266
ERVIDLLRVIHVAGK	ATXN10	331	Q9UBB4
LLRVIHVAGKETTNI	ATXN10	336	Q9UBB4
AQVKLLEKRVVHLGV	CMSS1	196	Q9BQ75
IRHLILSAIQGVTLA	ABCA13	2966	Q86UQ4
LIHAVTLGEKDIVIL	ANKRD36	201	A6QL64
VQLLGHRKRIIASLA	ANKS1A	816	Q92625
GRLLGIITKKDVLRH	CLCN4	731	P51793
IVETLKRHRVVVVAG	DHX29	581	Q7Z478
ITELIHIALLVHRGI	PDSS2	151	Q86YH6
ITDKGIIALRHLRNL	DMAC2L	166	Q99766
ILQEIHRRLGSVEVK	DPP10	611	Q8N608
HVAKEILLRVLTLFQ	ARMC10	271	Q8N2F6
SIGNAIHIVVVRLIL	ADAMTS12	286	P58397
SLGAHINVVLVRIIL	ADAMTS2	306	O95450
TLQQKLRLHIIEIIG	AP4E1	1071	Q9UPM8
KIGLKDVITLRRHVE	NPIPB3	136	Q92617
KRELQGLLQTLHTLE	RASSF10	426	A6NK89
KIGLKDVITLRRHVE	NPIPB12	136	F8W0I5
TLREIVIGVLHQLKN	MLX	281	Q9UH92
LHIASRLGKTEIVQL	ANK2	501	Q01484
LIHAVTLGEKDIVIL	ANKRD36C	201	Q5JPF3
EVELINVLKINLIGH	ANKS1B	921	Q7Z6G8
LLRIGITLAGHQKKI	EPHB1	951	P54762
EIKILLRFRHENIIG	MAPK1	71	P28482
IHLNRDILKTELGLV	PADI6	566	Q6TGC4
HIDIIRLLLQAGIDI	CASKIN1	201	Q8WXD9
ETIRKIHEQGLIAIL	CASK	821	O14936
ILEITVLRHGDRVIL	KIF14	876	Q15058
HITKFLITQILVALR	PRKD1	681	Q15139
LLKVALILGIEIHVN	MICAL3	166	Q7RTP6
SVKRHLLVIQILLIV	GPR82	246	Q96P67
LTIHLKEGRNLVVRD	MCTP2	196	Q6DN12
LSHVEQLLRAFILKI	MAD2L2	116	Q9UI95
IVLQQGEQRLIHKII	IKBKB	151	O14920
IDLRVVKQTVHGILL	LRIT2	366	A6NDA9
VHVLIGKVVLELERF	NAAA	76	Q02083
TLLERINVIVHLLGQ	EDRF1	1211	Q3B7T1
TDHIDQLKLILRLVG	MAPK14	226	Q16539
LRQHVIDVQILIDGK	DST	441	Q03001
IAEGTFVQLHKLVRL	LRFN1	201	Q9P244
VIGKLLHKRVVLASA	ASMTL	6	O95671
QTKLLILHQAVAVIL	TCF4	601	P15884
QGLILRSQLIVLLKH	CLCN7	676	P51798
LHLGLQDVVVLNSKR	CYP21A2	61	P08686
VRELIDGKLILTLTH	FABP3	106	P05413
IAVKVDQILRHSLLL	MGAT5B	131	Q3V5L5
LARIAIRGTIKKIIH	PCMTD2	246	Q9NV79
GIILHVIRTDIALHQ	OR51J1	46	Q9H342
VRTKQIRLGILHKFV	OR51L1	296	Q8NGJ5
VAEIVIHIRNKILTG	NUF2	11	Q9BZD4
EARKVVGALHQIITL	TPO	436	P07202
TLHLTVLRILKQLVD	CUL7	681	Q14999
LLQTHVTKEGERILL	KCNJ15	216	Q99712
REVIQERIIHLKGAL	KALRN	1576	O60229
LEGIRSLVRRHIKVI	NCKAP1L	411	P55160
LRIGVTLAGHQKKIL	EPHB3	966	P54753
KIGLKDVITLRRHVE	NPIPB5	136	A8MRT5
VEGQKHIVIFALRRI	KMT2B	2666	Q9UMN6
KIGLKDVITLRRHVE	NPIPB7	136	O75200
SNVVKIILIHIDSRL	OR2T27	41	Q8NH04
VHIKGRIIDTVAQVI	PARP4	626	Q9UKK3
RGVTHNIALLREVII	PCCA	476	P05165
IQKESTLHLVLRLRG	UBA52	61	P62987
KIGLKDVITLRRHVE	NPIPB15	136	A6NHN6
LLHIIIISGTDIVRQ	DZIP3	396	Q86Y13
ITVGELVNTHRLLLE	IQGAP3	1281	Q86VI3
VTRLIHLLGEKILGS	PNPLA7	686	Q6ZV29
LTNIIKILRHDIGAT	PAH	91	P00439
RIISETVGLKILEAH	MACF1	1646	Q9UPN3
GKIRLELLTIHQALE	PRR35	441	P0CG20
KEQLKLLEVLVGIIH	INTU	176	Q9ULD6
KIGLKDVITLRRHVE	NPIPB11	136	E5RHQ5
LLEVAVHVVVGKVLL	DIO1	16	P49895
SVLHIVSRVLIRELK	ABCC5	1026	O15440
KELQIFGIAIHRIIE	PRAMEF12	181	O95522
LTEKIHQTGLKVVRL	UPF1	541	Q92900
LLAGIISLNHVRQVI	FZD6	386	O60353
VIRLLVKRGAEVHLV	CPS1	231	P31327
DIRIGIVEHTLLQSK	IFT57	391	Q9NWB7
LVNEVLRGLDITLVH	BPIFA1	226	Q9NP55
KEHLGNRILVKLLTL	DOCK8	261	Q8NF50
HNKTKAIRLVLIVVI	CCR8	231	P51685
ETILNLLRKHQVVVI	DHX57	551	Q6P158
RVKVLLVLNLIAVAG	GALNT17	6	Q6IS24
ILGIVVFKIRDHLIS	ABCG5	636	Q9H222
TRGEIKQLNISHLLV	CEMIP2	1291	Q9UHN6
ILDVLRELHRQGVVV	CEP162	1376	Q5TB80
IKKILGLLSLQVLHE	EDDM13	76	A0A1B0GTR0
KSLLHLVLLGNQIER	ECM2	556	O94769
LARHVLTGREVAVKI	MARK1	76	Q9P0L2
ARHILTGREVAIKII	MARK4	76	Q96L34
LLSVLATVHVGQRLL	CYP1B1	26	Q16678
VLKVVQLEELLAVRH	DNAH9	2131	Q9NYC9
EKRLVVLVVLLAAGL	ECE1	66	P42892
RLVVSLGTVDVLKQH	CYP20A1	76	Q6UW02
LVKRLHLLSVEGQVI	CYP20A1	426	Q6UW02
RLHAIKEQLIQEGLL	HDAC6	111	Q9UBN7
IREQILLKGHVTQLK	GOLGA8B	206	A8MQT2
RLRHDEIITLLKNVG	GRIP2	106	Q9C0E4
ITALREIKILQLLKH	CDK9	61	P50750
RLKIVALVTIEIHAR	DNAH2	1706	Q9P225
KELNRLGVLIDLAHV	DPEP1	201	P16444
LDVLHIRLLVGSQIA	POLI	191	Q9UNA4
IGTIDEIQKLHIRTV	DDB1	701	Q16531
HTKIRELILDGSLQL	METTL4	151	Q8N3J2
KIGLKDVITLRRHVE	NPIPB9	151	F8W1W9
LGVHKVCIGQILRII	FOCAD	516	Q5VW36
KVLTRLKHIVELQII	FANCD2	811	Q9BXW9
KIGLKDVITLRRHVE	NPIPB13	136	A6NJU9
GNLLVIVLIRLDSHL	OR1E3	41	Q8WZA6
VHLVELLKQVRLELV	KBTBD12	211	Q3ZCT8
VTEVLHGLQLKIGIL	PHF20L1	781	A8MW92
IHGALLILNELVRIS	MTOR	261	P42345
GHIKQIIGILRDFIR	MAP3K15	1046	Q6ZN16
HLKVVGQIEHLVITL	NRIP3	161	Q9NQ35
KILHLLGKDSVQLLI	PIGB	126	Q92521
GVSKIRLLTIRILNH	UTP20	641	O75691
VLITAVVEVGRKHII	RNF133	171	Q8WVZ7
LLKILHSQVAGRLII	ROPN1B	71	Q9BZX4
VIVGLHQLLESRKRK	SSR1	221	P43307
KHVGVILQRGALVLL	SLC47A2	106	Q86VL8
HVIGNRLKLLLKEVS	SYNE1	8636	Q8NF91
LRIHVLLGLAITTLV	LRRN3	6	Q9H3W5
SLEERRKGAIILHVI	SLC24A2	126	Q9UI40
AIQVLRIHLLELEKV	PKNOX1	121	P55347
ILLIIVKLGELFHDL	SLC26A6	426	Q9BXS9
VVRQHGGITKLVALL	ODAD2	571	Q5T2S8
LRHLHILIGTSVVKI	KIR3DS1	336	Q14943
TLLRLLVVAVQGLIH	PIGQ	471	Q9BRB3
LIVREHGIRLLEAQI	EPPK1	1671	P58107
LIVREHGIRLLEAQI	EPPK1	3396	P58107
LLRKRHIGNDIVTIV	SIPA1L2	696	Q9P2F8
LGRHRITKTEVAIKI	SIK2	36	Q9H0K1
RVIIKLNIHVGNISL	SMARCB1	261	Q12824
AVRHVLLRQGVLGIK	RPS3	171	P23396
IRLHIREVGAQLVKK	SCP2D1	51	Q9UJQ7
GEVIHVKILGILALI	PPA2	181	Q9H2U2
LQRVHKRIQDIVGIL	NOP2	236	P46087
RHSRVVKLLGVIIEE	RIPK1	71	Q13546
LIKGKTHSQLLIIDR	STXBP3	226	O00186
NLGLILVVIRDSQLH	OR5T2	81	Q8NGG2
NLHSVLVIKLQELIR	RANBP6	496	O60518
QRSIILHLISQLKLG	OSBPL10	396	Q9BXB5
HVGVILQRSALVLLL	SLC47A1	111	Q96FL8
LLEHLAGERRQTKVI	ST18	331	O60284
FLRQIQEVLKLTLGH	CLEC20A	371	Q6ZU45
IAINVHLDTLKKVRI	CNGA1	461	P29973
LSQCLIERGHKVIIV	PIGA	56	P37287
IIVVVNGIDLIKHRK	TAS2R1	26	Q9NYW7
ERILVIRKDLGNIIH	PIK3R4	341	Q99570
DETIGVVHLVLRRLL	RNF213	4636	Q63HN8
RTVVLLLRILSEKHG	UST	116	Q9Y2C2
SQLKLREGEITHLQL	TMF1	991	P82094
LRKHICIIVLNLGEE	ZFAT	131	Q9P243
LALHNKRKEVVLTII	TRPA1	586	O75762
QTVHKLLIVVELLLG	PSMD3	326	O43242
VTILTSQLKHLLGVR	SLC26A1	221	Q9H2B4
VIFLAKILHLGLKIR	SLC27A5	91	Q9Y2P5
SEHLSLILGNILKII	RYR3	3166	Q15413
LLKILHSQVAGRLII	ROPN1	71	Q9HAT0
KLLLASKEQVLHRVV	RNF10	331	Q8N5U6
VGLLANLVHSLLVKV	TMEM115	236	Q12893
QVLIQKHLVRLLSVV	UBR1	1371	Q8IWV7
HVVVLLLRGLSQKAT	TANGO6	1021	Q9C0B7
HIGGVLLKIVEQINR	FERMT3	41	Q86UX7
IEVLICLHTRVLEKL	SMCO1	81	Q147U7
ILKDHGIRLLEAQIA	PLEC	4171	Q15149
EVIATVIRKLLNHIL	PSME4	866	Q14997
IQKESTLHLVLRLRG	UBB	61	P0CG47
NKIGLKDVITLRRHV	NPIPB2	116	A6NJ64
HLKDVILLTAIVQVL	TMEM208	101	Q9BTX3
QKSLLIIHLRVHTGE	ZNF630	526	Q2M218
SGIIRLHTIKQIIDQ	TJP1	686	Q07157
LLINASVIIIIRGHR	UBR3	1816	Q6ZT12
ILKELVQRGHEVTVL	UGT2B10	41	P36537
LVGVLIHCLKQLIGV	SCN7A	226	Q01118
IHCLKQLIGVIILTL	SCN7A	231	Q01118
IIRSLNVHVSGALLI	TARBP1	1591	Q13395
VHGTLEVLHLLVIRL	TOGARAM1	411	Q9Y4F4
EVLHLLVIRLGEQVQ	TOGARAM1	416	Q9Y4F4
IQKESTLHLVLRLRG	UBC	61	P0CG48
IQKESTLHLVLRLRG	UBC	441	P0CG48
KIIFRVGLVLLKHAL	TBC1D10A	301	Q9BXI6
IQKESTLHLVLRLRG	RPS27A	61	P62979
GKVHILLNIKEFILV	ZNF781	211	Q8N8C0
LHAIRKEVVGAVELL	TRPC4	101	Q9UBN4
ELGLVTHLVTKLRAN	NFKB2	646	Q00653