Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	RAD51D ATP6V1B2 ATP6V0C ATP6V0A1 KIF1A KIF26B KIF12 ABCF2 UPF1 CLPX STARD9 CHD5 MACF1 CARNS1 PIF1 MOV10	9.76e-05	614	174	16	GO:0140657
GeneOntologyMolecularFunction	pyrophosphatase activity	CPLANE2 RAD51D KIF1A KIF12 ABCF2 NUDT22 UPF1 CLPX RAB44 RGS3 RHOV CHD5 ENTPD6 MACF1 CARNS1 PIF1 MOV10 MX1	3.97e-04	839	174	18	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	CPLANE2 RAD51D KIF1A KIF12 ABCF2 NUDT22 UPF1 CLPX RAB44 RGS3 RHOV CHD5 ENTPD6 MACF1 CARNS1 PIF1 MOV10 MX1	4.03e-04	840	174	18	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	CPLANE2 RAD51D KIF1A KIF12 ABCF2 NUDT22 UPF1 CLPX RAB44 RGS3 RHOV CHD5 ENTPD6 MACF1 CARNS1 PIF1 MOV10 MX1	4.03e-04	840	174	18	GO:0016818
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	CPLANE2 RAD51D KIF1A KIF12 ABCF2 UPF1 CLPX RAB44 RGS3 RHOV CHD5 ENTPD6 MACF1 CARNS1 PIF1 MOV10 MX1	4.50e-04	775	174	17	GO:0017111
Domain	ACTININ_2	FLNB SYNE1 SPTBN4 MACF1	5.36e-05	23	172	4	PS00020
Domain	ACTININ_1	FLNB SYNE1 SPTBN4 MACF1	5.36e-05	23	172	4	PS00019
Domain	Actinin_actin-bd_CS	FLNB SYNE1 SPTBN4 MACF1	5.36e-05	23	172	4	IPR001589
Domain	-	KDM5B ARID5A ARID3C	3.22e-04	15	172	3	1.10.150.60
Domain	BRIGHT	KDM5B ARID5A ARID3C	3.22e-04	15	172	3	SM00501
Domain	ARID_dom	KDM5B ARID5A ARID3C	3.22e-04	15	172	3	IPR001606
Domain	ARID	KDM5B ARID5A ARID3C	3.22e-04	15	172	3	PS51011
Domain	ARID	KDM5B ARID5A ARID3C	3.22e-04	15	172	3	PF01388
Domain	-	KIF1A KIF26B KIF12 STARD9	7.07e-04	44	172	4	3.40.850.10
Domain	Kinesin	KIF1A KIF26B KIF12 STARD9	7.07e-04	44	172	4	PF00225
Domain	KISc	KIF1A KIF26B KIF12 STARD9	7.07e-04	44	172	4	SM00129
Domain	KINESIN_MOTOR_1	KIF1A KIF26B KIF12 STARD9	7.07e-04	44	172	4	PS00411
Domain	Kinesin_motor_dom	KIF1A KIF26B KIF12 STARD9	7.07e-04	44	172	4	IPR001752
Domain	KINESIN_MOTOR_2	KIF1A KIF26B KIF12 STARD9	7.07e-04	44	172	4	PS50067
Domain	Anaphylatoxin_comp_syst	C4A C4B	8.28e-04	5	172	2	IPR018081
Domain	Laminin_domII	LAMA3 LAMA5	8.28e-04	5	172	2	IPR010307
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	8.28e-04	5	172	2	IPR001840
Domain	Laminin_aI	LAMA3 LAMA5	8.28e-04	5	172	2	IPR009254
Domain	Laminin_I	LAMA3 LAMA5	8.28e-04	5	172	2	PF06008
Domain	Laminin_II	LAMA3 LAMA5	8.28e-04	5	172	2	PF06009
Domain	VWA	COL6A3 VWA1 VWA7 ITGAD HMCN2	1.07e-03	84	172	5	SM00327
Domain	Spectrin	SYNE1 SPTBN4 MACF1	1.19e-03	23	172	3	PF00435
Domain	ANATO	C4A C4B	1.72e-03	7	172	2	SM00104
Domain	ANAPHYLATOXIN_2	C4A C4B	1.72e-03	7	172	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	1.72e-03	7	172	2	PS01177
Domain	ANATO	C4A C4B	1.72e-03	7	172	2	PF01821
Domain	Anaphylatoxin/fibulin	C4A C4B	1.72e-03	7	172	2	IPR000020
Domain	HECT	HECTD3 UBE3C HERC6	1.91e-03	27	172	3	PF00632
Domain	HECTc	HECTD3 UBE3C HERC6	1.91e-03	27	172	3	SM00119
Domain	HECT_dom	HECTD3 UBE3C HERC6	1.91e-03	27	172	3	IPR000569
Domain	HECT	HECTD3 UBE3C HERC6	1.91e-03	27	172	3	PS50237
Domain	Ig_I-set	VSIG2 DSCAM OBSCN IGSF5 ESAM LINGO2 HMCN2	1.93e-03	190	172	7	IPR013098
Domain	I-set	VSIG2 DSCAM OBSCN IGSF5 ESAM LINGO2 HMCN2	1.93e-03	190	172	7	PF07679
Domain	PDZ	WHRN HTRA1 RGS3 AHNAK RIMS1 PDZD2	1.97e-03	141	172	6	PF00595
Domain	FHA	KIF1A STARD9 MDC1	2.12e-03	28	172	3	SM00240
Domain	VWF_A	COL6A3 VWA1 VWA7 ITGAD HMCN2	2.23e-03	99	172	5	IPR002035
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	2.28e-03	8	172	2	IPR019565
Domain	Thiol-ester_cl	C4A C4B	2.28e-03	8	172	2	PF10569
Domain	LAMININ_IVA	LAMA3 LAMA5	2.28e-03	8	172	2	PS51115
Domain	Laminin_B	LAMA3 LAMA5	2.28e-03	8	172	2	PF00052
Domain	MacrogloblnA2_CS	C4A C4B	2.28e-03	8	172	2	IPR019742
Domain	LamB	LAMA3 LAMA5	2.28e-03	8	172	2	SM00281
Domain	Laminin_IV	LAMA3 LAMA5	2.28e-03	8	172	2	IPR000034
Domain	Spectrin_repeat	SYNE1 SPTBN4 MACF1	2.35e-03	29	172	3	IPR002017
Domain	PDZ	WHRN HTRA1 RGS3 AHNAK RIMS1 PDZD2	2.51e-03	148	172	6	SM00228
Domain	-	WHRN HTRA1 RGS3 AHNAK RIMS1 PDZD2	2.68e-03	150	172	6	2.30.42.10
Domain	Ig_E-set	FLNB CAMTA2 TRIM3 ARRDC2 PLXNB1	2.76e-03	104	172	5	IPR014756
Domain	PDZ	WHRN HTRA1 RGS3 AHNAK RIMS1 PDZD2	2.77e-03	151	172	6	PS50106
Domain	FHA	KIF1A STARD9 MDC1	2.85e-03	31	172	3	PF00498
Domain	PDZ	WHRN HTRA1 RGS3 AHNAK RIMS1 PDZD2	2.87e-03	152	172	6	IPR001478
Domain	CH	FLNB SYNE1 SPTBN4 MACF1	3.04e-03	65	172	4	SM00033
Domain	SPEC	SYNE1 SPTBN4 MACF1	3.13e-03	32	172	3	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 SPTBN4 MACF1	3.13e-03	32	172	3	IPR018159
Domain	IG_FLMN	FLNB TRIM3	3.61e-03	10	172	2	SM00557
Domain	A2M	C4A C4B	3.61e-03	10	172	2	PF00207
Domain	A2M_N_2	C4A C4B	3.61e-03	10	172	2	IPR011625
Domain	A2M_comp	C4A C4B	3.61e-03	10	172	2	IPR011626
Domain	A2M_recep	C4A C4B	3.61e-03	10	172	2	PF07677
Domain	A2M_comp	C4A C4B	3.61e-03	10	172	2	PF07678
Domain	A2M_N	C4A C4B	3.61e-03	10	172	2	PF01835
Domain	A2M_N	C4A C4B	3.61e-03	10	172	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	3.61e-03	10	172	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	3.61e-03	10	172	2	PS00477
Domain	A2M_N_2	C4A C4B	3.61e-03	10	172	2	PF07703
Domain	Macroglobln_a2	C4A C4B	3.61e-03	10	172	2	IPR001599
Domain	CH	FLNB SYNE1 SPTBN4 MACF1	3.97e-03	70	172	4	PF00307
Domain	EGF_Lam	SCARF2 LAMA3 LAMA5	4.05e-03	35	172	3	SM00180
Domain	Laminin_EGF	SCARF2 LAMA3 LAMA5	4.05e-03	35	172	3	PF00053
Domain	-	FLNB SYNE1 SPTBN4 MACF1	4.18e-03	71	172	4	1.10.418.10
Domain	-	KIF1A STARD9 MDC1	4.38e-03	36	172	3	2.60.200.20
Domain	FHA_dom	KIF1A STARD9 MDC1	4.38e-03	36	172	3	IPR000253
Domain	Filamin	FLNB TRIM3	4.39e-03	11	172	2	PF00630
Domain	FILAMIN_REPEAT	FLNB TRIM3	4.39e-03	11	172	2	PS50194
Domain	Filamin/ABP280_rpt	FLNB TRIM3	4.39e-03	11	172	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNB TRIM3	4.39e-03	11	172	2	IPR017868
Domain	CH	FLNB SYNE1 SPTBN4 MACF1	4.61e-03	73	172	4	PS50021
Domain	CH-domain	FLNB SYNE1 SPTBN4 MACF1	5.08e-03	75	172	4	IPR001715
Domain	LAM_G_DOMAIN	LAMA3 LAMA5 NRXN2	5.11e-03	38	172	3	PS50025
Domain	Laminin_EGF	SCARF2 LAMA3 LAMA5	5.11e-03	38	172	3	IPR002049
Domain	Laminin_G_2	LAMA3 LAMA5 NRXN2	5.91e-03	40	172	3	PF02210
Domain	SSD	NPC1L1 DISP2	6.15e-03	13	172	2	IPR000731
Domain	SSD	NPC1L1 DISP2	6.15e-03	13	172	2	PS50156
Domain	Kinesin_motor_CS	KIF1A KIF12 STARD9	6.33e-03	41	172	3	IPR019821
Domain	VWFA	COL6A3 VWA1 ITGAD HMCN2	6.96e-03	82	172	4	PS50234
Domain	Kinesin-like_fam	KIF1A KIF26B KIF12	7.23e-03	43	172	3	IPR027640
Domain	LamG	LAMA3 LAMA5 NRXN2	7.71e-03	44	172	3	SM00282
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WHRN PALD1 ZNF536 SYNE1 CAMTA2 ZHX2 DCAF5 RUSC2 SUGP2 STARD9 MCM3AP MACF1 DISP2 TRAK2 UBE3C PUM1 PDZD2	4.71e-11	407	179	17	12693553
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZXDC PALD1 MRPS12 OBSCN LAMA5 DCTN1 MPRIP CNPPD1 FASN SLC38A10 SUGP2 AHNAK CHD5 MCM3AP ZNF516 SLC7A5 DISP2 UBE3C SNAPC4 ARRDC2 PUM1 C1orf50	6.72e-08	1105	179	22	35748872
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLNB ATP6V1B2 ATP6V0C HTRA1 ATP6V0A1 CARMIL2 PRXL2B SYNE1 GRIA2 UPF1 ARHGAP39 DCTN1 ADAM22 TRIM3 MPRIP SPTBN4 FASN SUGP2 NRXN2 SFXN3 MACF1 C4A C4B RIMS1	3.80e-07	1431	179	24	37142655
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	WHRN SPTBN4 NRXN2 MCM3AP MACF1 CARNS1 TANGO6 PDZD2	4.01e-07	130	179	8	12421765
Pubmed	The complete exon-intron structure of a human complement component C4A gene. DNA sequences, polymorphism, and linkage to the 21-hydroxylase gene.	C4A C4B TNXA	1.33e-06	5	179	3	1988494
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNB IMPDH2 NOC2L ABCF2 UPF1 SRBD1 CLPX DCTN1 AKAP8L MPRIP FASN PLAA SUGP2 AHNAK MCM3AP MDC1 SFXN3 UGDH MACF1 PUM1 NOP2 MOV10	2.01e-06	1353	179	22	29467282
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	SLC25A24 SCARF2 VPS13C SYNE1 LAMA5 C1orf167 UPF1 DCTN1 FASN MDC1 UGDH ZSCAN2 PUM1 NOP2 MOV10 TANGO6	2.05e-06	754	179	16	35906200
Pubmed	Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region. Molecular cloning, exon-intron structure, composite retroposon, and breakpoint of gene duplication.	C4A C4B TNXA	2.65e-06	6	179	3	8132574
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	FLNB SYNE1 LINGO2 FER1L6 MPRIP AHNAK MDC1 MACF1 NOP2	3.81e-06	234	179	9	36243803
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	ATP6V1B2 ABCF2 UPF1 CLPX DCTN1 MPRIP FASN AHNAK SFXN3 SLC7A5	5.54e-06	312	179	10	37120454
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNB ELOA2 NOC2L SYNE1 PCDHGA1 RALYL GRIA2 ABCF2 SRBD1 CLPX DCTN1 AKAP8L FER1L6 SPTBN4 FASN STARD9 AHNAK CHD5 MARF1 MACF1 SLC7A5 RIMS1	5.56e-06	1442	179	22	35575683
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	SYNE1 GRIA2 ARHGAP39 DCTN1 ADAM22 MPRIP SPTBN4 SFXN3 MACF1	6.72e-06	251	179	9	27507650
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	SLC25A24 FLNB IMPDH2 LAMA5 UPF1 DCTN1 MPRIP FASN AHNAK SFXN3 UGDH UBE3C MOV10 MX1	7.32e-06	647	179	14	26618866
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNB IMPDH2 KIF1A NOC2L UPF1 FASN SUGP2 AHNAK MCM3AP MDC1 MACF1 PUM1 NOP2 MOV10	8.12e-06	653	179	14	22586326
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	FAM234A ATP6V0A1 IMPDH2 KIF1A HECTD3 EARS2 SCARF2 NOC2L ABCF2 UPF1 B3GAT3 FASN PLAA TMEM9 TELO2 TIMELESS PUM1	8.33e-06	942	179	17	31073040
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	FLNB NOC2L LAMA5 ABCF2 UPF1 DCTN1 AKAP8L MPRIP FASN SUGP2 MDC1 SLC7A5 C4A PUM1 NOP2 MOV10	8.86e-06	847	179	16	35850772
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	VPS13C ABCF2 LINGO2 MPRIP SLC38A10 TTLL2 MDC1 MX1	9.66e-06	199	179	8	23382691
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	TPSAB1 COL6A3 HTRA1 LAMA3 LAMA5 VWA1 HMCN2	1.13e-05	146	179	7	27068509
Pubmed	Human transcription factor protein interaction networks.	ZNF536 CCDC8 IMPDH2 MRPS12 HIC2 UPF1 CLPX ZHX2 DCAF5 AKAP8L MPRIP ZBTB7A SUGP2 CHD5 MDC1 ZNF516 MARF1 PUM1 NOP2 MOV10 TANGO6	1.61e-05	1429	179	21	35140242
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	FLNB ATP6V1B2 HTRA1 ATP6V0A1 IMPDH2 VPS13C SYNE1 LAMA5 ABCF2 UPF1 DCTN1 FASN AHNAK UGDH MOV10	1.94e-05	803	179	15	36517590
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF536 HTRA1 HECTD3 EARS2 RALYL HIC2 CLPX DCAF5 AKAP8L PASK ZBTB7A HMCN2 SUGP2 TELO2 CHD5 MCM3AP MACF1 C1orf50	2.02e-05	1116	179	18	31753913
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EARS2 VPS13C LAMA5 HIC2 PASK NRXN2 TELO2 CHD5 MDC1 ZNF516 CARNS1 PLXNB1	2.11e-05	529	179	12	14621295
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	2.63e-05	2	179	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	2.63e-05	2	179	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	2.63e-05	2	179	2	15998580
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	2.63e-05	2	179	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	2.63e-05	2	179	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	2.63e-05	2	179	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	2.63e-05	2	179	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	2.63e-05	2	179	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	2.63e-05	2	179	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	2.63e-05	2	179	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	2.63e-05	2	179	2	17645767
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	2.63e-05	2	179	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	2.63e-05	2	179	2	12207352
Pubmed	The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.	TPSAB1 TPSB2	2.63e-05	2	179	2	10500112
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	2.63e-05	2	179	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	2.63e-05	2	179	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	2.63e-05	2	179	2	27758680
Pubmed	Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.	TPSAB1 TPSB2	2.63e-05	2	179	2	8434231
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	2.63e-05	2	179	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	2.63e-05	2	179	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	2.63e-05	2	179	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	2.63e-05	2	179	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	2.63e-05	2	179	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	2.63e-05	2	179	2	23749435
Pubmed	CTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebrates.	VSIG2 ESAM	2.63e-05	2	179	2	9862345
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	2.63e-05	2	179	2	23918728
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	2.63e-05	2	179	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	2.63e-05	2	179	2	3037333
Pubmed	In situ-RT-PCR and immunohistochemistry for the localisation of the mRNA of the alpha 3 chain of laminin and laminin-5 during human organogenesis.	LAMA3 LAMA5	2.63e-05	2	179	2	12382139
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	2.63e-05	2	179	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	2.63e-05	2	179	2	4216347
Pubmed	Cloning and characterization of a second complementary DNA for human tryptase.	TPSAB1 TPSB2	2.63e-05	2	179	2	2203827
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	2.63e-05	2	179	2	1699796
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	2.63e-05	2	179	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	2.63e-05	2	179	2	2997024
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	2.63e-05	2	179	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	2.63e-05	2	179	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	2.63e-05	2	179	2	8428773
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	2.63e-05	2	179	2	21857912
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	2.63e-05	2	179	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	2.63e-05	2	179	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	2.63e-05	2	179	2	4514997
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	2.63e-05	2	179	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	2.63e-05	2	179	2	5919331
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	2.63e-05	2	179	2	3167981
Pubmed	Biological function of laminin-5 and pathogenic impact of its deficiency.	LAMA3 LAMA5	2.63e-05	2	179	2	17000025
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	2.63e-05	2	179	2	7545960
Pubmed	Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.	TPSAB1 TPSB2	2.63e-05	2	179	2	10898108
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	2.63e-05	2	179	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	2.63e-05	2	179	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	2.63e-05	2	179	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	2.63e-05	2	179	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	2.63e-05	2	179	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	2.63e-05	2	179	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	2.63e-05	2	179	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	2.63e-05	2	179	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	2.63e-05	2	179	2	29080553
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	2.63e-05	2	179	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	2.63e-05	2	179	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	2.63e-05	2	179	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	2.63e-05	2	179	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	2.63e-05	2	179	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	2.63e-05	2	179	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	2.63e-05	2	179	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	2.63e-05	2	179	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	2.63e-05	2	179	2	2387317
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	2.63e-05	2	179	2	8132550
Pubmed	Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.	TPSAB1 TPSB2	2.63e-05	2	179	2	9521329
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	2.63e-05	2	179	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	2.63e-05	2	179	2	26814708
Pubmed	cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).	C4A C4B	2.63e-05	2	179	2	6192448
Pubmed	Complete primary structure of human C4a anaphylatoxin.	C4A C4B	2.63e-05	2	179	2	6167582
Pubmed	Genes identified through genome-wide association studies of osteonecrosis in childhood acute lymphoblastic leukemia patients.	SLC25A24 SH3YL1	2.63e-05	2	179	2	31686588
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	2.63e-05	2	179	2	16908004
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	2.63e-05	2	179	2	1438267
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	2.63e-05	2	179	2	7365238
Pubmed	Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.	TPSAB1 TPSB2	2.63e-05	2	179	2	2187193
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	2.63e-05	2	179	2	19150565
Cytoband	8q24.1	SQLE FER1L6	3.13e-04	7	179	2	8q24.1
Cytoband	16p13.3	TPSAB1 ATP6V0C FAM234A E4F1 TELO2 TPSB2	4.14e-04	244	179	6	16p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr8q24	AARD SQLE ARHGAP39 ZHX2 FER1L6 PARP10 WDR97	5.19e-04	355	179	7	chr8q24
Cytoband	9q32	WHRN KIF12 RGS3	8.33e-04	47	179	3	9q32
Cytoband	Ensembl 112 genes in cytogenetic band chr9q32	WHRN KIF12 RGS3	9.98e-04	50	179	3	chr9q32
GeneFamily	AT-rich interaction domain containing	KDM5B ARID5A ARID3C	9.97e-05	15	112	3	418
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF1A KIF26B KIF12 STARD9	1.86e-04	46	112	4	622
GeneFamily	PDZ domain containing	WHRN HTRA1 RGS3 AHNAK RIMS1 PDZD2	3.68e-04	152	112	6	1220
GeneFamily	V-type ATPases	ATP6V1B2 ATP6V0C ATP6V0A1	3.74e-04	23	112	3	415
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	VSIG2 DSCAM OBSCN IGSF5 LINGO2 HMCN2	4.99e-04	161	112	6	593
GeneFamily	Dynactin	DCTN1 DCTN6	5.61e-04	6	112	2	943
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	1.33e-03	9	112	2	1234
GeneFamily	UPF1 like RNA helicases	UPF1 MOV10	2.02e-03	11	112	2	1169
GeneFamily	Laminin subunits	LAMA3 LAMA5	2.41e-03	12	112	2	626
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP10 TNKS2	4.87e-03	17	112	2	684
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	ATP6V1B2 ATP6V0A1 CARMIL2 RALYL RUSC1 CASTOR2 B3GAT3 PTPRN RHOV CHD5 DISP2 RIMS1	2.28e-11	193	179	12	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	HTRA1 OBSCN C2orf72 SPTBN4 FASN EXD3 AJAP1 NRXN2 CHD5 ANKRD24	9.03e-09	200	179	10	61d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	HTRA1 OBSCN C2orf72 SPTBN4 FASN EXD3 AJAP1 NRXN2 CHD5 ANKRD24	9.03e-09	200	179	10	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	droplet-Tongue-nan-3m-Epithelial-suprabasal_interpapillary\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM5B IKZF2 PRXL2B SQLE CLPX DMKN RHOV AHNAK HSD17B2	8.45e-08	191	179	9	abdd93b2313e635f75a750d051a6a01ddc4e2df9
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB KIF1A SQLE KIF12 SLC38A10 PTPRN ZNF516 DISP2 ECHDC2	9.23e-08	193	179	9	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB KIF1A SQLE KIF12 SLC38A10 PTPRN ZNF516 DISP2 ECHDC2	9.23e-08	193	179	9	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIF1A RALYL GRIA2 LINGO2 C2orf72 SPTBN4 PTPRN RIMS1	4.34e-07	169	179	8	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	PALD1 TPSAB1 HTRA1 SCARF2 RAB44 HMCN2 NKD2 NRXN2	9.71e-07	188	179	8	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WHRN FLNB IKZF2 SYNE1 DMKN STARD9 MACF1 CTSW	1.09e-06	191	179	8	f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WHRN FLNB IKZF2 SYNE1 DMKN STARD9 MACF1 CTSW	1.09e-06	191	179	8	1161e465c50c2071764279e01cf08b1048cce0e3
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	WHRN FLNB IKZF2 SYNE1 DMKN STARD9 MACF1 CTSW	1.09e-06	191	179	8	7a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCell	Control-Lymphoid_T/NK-NK_CD56bright\|Control / Disease group, lineage and cell class	WHRN FLNB IKZF2 SYNE1 DMKN STARD9 MACF1 CTSW	1.09e-06	191	179	8	e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	WHRN FLNB IKZF2 SYNE1 DMKN STARD9 MACF1 CTSW	1.09e-06	191	179	8	c023ca893ceae19b54967096f6e2588dc39fa268
ToppCell	background-Cholangiocytes\|background / Sample and Cell Type and Tumor Cluster (all cells)	VSIG2 GGT6 RALYL KIF12 SH3YL1 AJAP1 DMKN ARRDC2	1.18e-06	193	179	8	9152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM5B IKZF2 GGT6 PRXL2B SQLE DMKN RHOV HSD17B2	1.28e-06	195	179	8	c54b19e31efe2c9ae690062569da7c0f1120a1d8
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF1A VPS13C KIF12 SLC38A10 PTPRN ZNF516 MACF1 TNKS2	1.28e-06	195	179	8	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	BL-critical-LOC-Myeloid-Basophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PALD1 TPSAB1 SP4 IKZF2 ADAM22 WDR97 TRAK2	4.25e-06	162	179	7	25ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RALYL GRIA2 LINGO2 C2orf72 SPTBN4 PTPRN RIMS1	4.61e-06	164	179	7	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	facs-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l26\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPSAB1 C14orf93 KIF12 RAB44 FES DISP2 TPSB2	4.80e-06	165	179	7	23955e3373660f827518e723ac62fba99753f375
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 SCARF2 CPED1 UGDH C4B HAS1 PIF1	8.80e-06	181	179	7	c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	KIF1A RALYL GRIA2 LINGO2 SPTBN4 PTPRN RIMS1	9.12e-06	182	179	7	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	KIF26B RALYL ZBTB7A RHOV CHD5 DISP2 RIMS1	1.05e-05	186	179	7	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 CCDC8 PDK4 CPED1 DMKN C4A HSD17B2	1.05e-05	186	179	7	d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCell	Healthy_donor-NK_CD56bright\|World / disease group, cell group and cell class (v2)	WHRN FLNB SYNE1 ITGAD DMKN STARD9 CTSW	1.13e-05	188	179	7	8ee359199c61c3b5b498ac35148390db5cc1a836
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 HTRA1 SCARF2 VWA1 C4B HAS1 ECHDC2	1.34e-05	193	179	7	fe9720185929ef849edd1b8eb4854306b392e5a2
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CARMIL2 RALYL SPTBN4 PTPRN RHOV CHD5 DISP2	1.34e-05	193	179	7	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	Control-NK_CD56bright\|Control / Disease condition and Cell class	WHRN FLNB KIF26B DMKN STARD9 FES CTSW	1.34e-05	193	179	7	8b1e7a226a6057e1097c1525984127b54e823876
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF1A VPS13C KIF12 SLC38A10 PTPRN ZNF516 MACF1	1.43e-05	195	179	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_late\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	VSIG2 KIF12 LAMA3 VWA1 SH3YL1 ARSL DMKN	1.48e-05	196	179	7	75e9e430a4f55ef10f2e3132afa690fc8bfaff83
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GRIA2 LINGO2 ADAM22 SPTBN4 CHD5 RIMS1	1.48e-05	196	179	7	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	wk_20-22-Epithelial-Distal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	VSIG2 GGT6 KIF12 LAMA3 LAMA5 ARSL DMKN	1.48e-05	196	179	7	cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HTRA1 DSCAM RALYL GRIA2 EXTL1 NRXN2 PDZD2	1.48e-05	196	179	7	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HTRA1 DSCAM RALYL GRIA2 EXTL1 NRXN2 PDZD2	1.48e-05	196	179	7	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	VSIG2 KIF12 LAMA3 VWA1 SH3YL1 ARSL DMKN	1.48e-05	196	179	7	00bef0e47739932fd1da109cd607de0789d14ca5
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	COL6A3 SYNE1 ZHX2 NRXN2 AHNAK MACF1 MX1	1.58e-05	198	179	7	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 RALYL GRIA2 ADAM22 SPTBN4 CHD5 RIMS1	1.58e-05	198	179	7	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HTRA1 DSCAM RALYL GRIA2 EXTL1 NRXN2 PDZD2	1.58e-05	198	179	7	02d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCell	wk_15-18-Epithelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	VSIG2 KIF12 LAMA3 LAMA5 SH3YL1 ARSL DMKN	1.58e-05	198	179	7	12bbe77c3d68bf1e545949dbb1eb49ed3641de3d
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	COL6A3 CCDC8 HTRA1 SCARF2 NKD2 NRXN2 HAS1	1.58e-05	198	179	7	74f2c7ef702b25a5b99e56121229e678ed992524
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	IKZF2 SYNE1 RGS3 AHNAK MACF1 HERC6 MX1	1.68e-05	200	179	7	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EXTL1 AJAP1 RHOV FES SLC7A5 HSD17B2	2.11e-05	139	179	6	505bf5a483fc2ba69377db9850c3b26ab2f416d1
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL6A3 ZNF536 HTRA1 LAMA3 LAMA5 NRXN2	2.79e-05	146	179	6	47368f981180ca6a8c81a50f7f9430f12456f609
ToppCell	mild_COVID-19_(asymptomatic)-MAIT\|World / disease group, cell group and cell class (v2)	WHRN POMT1 ADAM22 SPTBN4 SLC7A5 HERC6	3.63e-05	153	179	6	2b4c69f6db17927d6506a645ac058133e60b0103
ToppCell	mild_COVID-19_(asymptomatic)-MAIT\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	WHRN POMT1 ADAM22 SPTBN4 SLC7A5 CTSW	3.63e-05	153	179	6	26852f3d8f80e102e24bcb90e24aac26fdc9a32c
ToppCell	Adult-Immune-mast_cell-D231\|Adult / Lineage, Cell type, age group and donor	TPSAB1 IGSF5 RAB44 PASK AJAP1 TPSB2	4.19e-05	157	179	6	4c63bb91f8708644e6ce2500072a4eeb8e1079dd
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 LRRC45 SYNE1 LAMA3 LAMA5 CASTOR2	4.34e-05	158	179	6	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 LRRC45 SYNE1 LAMA3 LAMA5 CASTOR2	4.34e-05	158	179	6	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KIF1A RALYL GRIA2 LINGO2 PTPRN RIMS1	4.50e-05	159	179	6	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	10x5'-bone_marrow-Mast\|bone_marrow / Manually curated celltypes from each tissue	TPSAB1 QRICH2 RAB44 EXD3 HAS1 TPSB2	4.50e-05	159	179	6	c3d3570e83c5d25cc92fa3a7a8f0dc2f89a72913
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B RALYL PCDH17 FER1L6 CNGB1 PLXNB1	4.66e-05	160	179	6	af84da18c85037f49f55e8958f00f12140226982
ToppCell	ICU-SEP-Lymphocyte-T_NK-gdT\|ICU-SEP / Disease, Lineage and Cell Type	IKZF2 AARD KIF26B STARD9 ANKRD24 CTSW	4.66e-05	160	179	6	0a14b1fed54a09c0caf263662b5bd426466c7189
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B RALYL PCDH17 FER1L6 CNGB1 PLXNB1	4.66e-05	160	179	6	f7ca98beaa24f9674d503588eb15d341c4135d77
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B RALYL PCDH17 FER1L6 CNGB1 PLXNB1	4.66e-05	160	179	6	a76ad44b5f25f59d6b9333fb45f8bb96196a3090
ToppCell	10x5'-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	TPSAB1 QRICH2 RAB44 EXD3 HAS1 TPSB2	4.82e-05	161	179	6	15ba7e69699558353cfeecdcf1dbc2e147379ed6
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	VSIG2 SYNE1 LAMA5 VWA1 DMKN HAS1	4.99e-05	162	179	6	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 CCDC8 HTRA1 KIF26B UGDH HAS1	4.99e-05	162	179	6	56f1789e69a6cb29956e46aba92b290847327c1f
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	COL6A3 SCARF2 KIF26B SQLE HMCN2 PTPRN	5.34e-05	164	179	6	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 DSCAM IGSF5 RGS3 AHNAK CTSW	5.52e-05	165	179	6	e24621c8d4dbafb407033d832fe9337f13feae34
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CARMIL2 ASAP3 LYSMD1 VWA1 ENTPD6 PDZD2	5.71e-05	166	179	6	f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	ZXDC OBSCN VWA7 PUM1 SLFNL1 PLXNB1	5.71e-05	166	179	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 DSCAM RGS3 C2orf72 AHNAK CTSW	5.91e-05	167	179	6	92ddabbe55315856d8ea6f8db1560b6d97636bac
ToppCell	PND03-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PALD1 NUDT22 SLC20A1 TIMELESS UBE3C MX1	6.11e-05	168	179	6	cc0dd43d5cda01e643d8e8d74ec7617d61890760
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 SCARF2 OBSCN CPED1 C4A C4B	6.11e-05	168	179	6	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	COVID-19_Severe-CD4+_CTL\|World / disease group, cell group and cell class	SP4 SYNE1 EXTL1 RHOV CARNS1 CTSW	6.31e-05	169	179	6	8c8168ac93a808d7b4756e4491db2b2979df1c1f
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIF1A C2orf72 SPTBN4 PTPRN CHD5 NPC1L1	6.31e-05	169	179	6	96a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	VSIG2 KIF1A LAMA3 LAMA5 DMKN PDZD2	6.52e-05	170	179	6	4cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCell	severe-Myeloid-Eosinophils\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	FLNB IKZF2 PDK4 SYNE1 RAB44 TPSB2	6.52e-05	170	179	6	863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	VSIG2 KIF1A LAMA3 LAMA5 DMKN PDZD2	6.52e-05	170	179	6	36c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCell	RV-03._Atrial_Cardiomyocyte\|RV / Chamber and Cluster_Paper	PDK4 EID2 OBSCN VWA7 ARID5A	6.60e-05	105	179	5	49e16b11f16e83a7d17d162c14bce991201bcc2a
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	TPSAB1 AARD ADAM22 SLC7A5 CTSW TPSB2	6.95e-05	172	179	6	c477008444d2d71071177807870d7455e90c2fad
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VSIG2 ESAM PCDH17 KPNA7 HERC6 CNGB1	6.95e-05	172	179	6	c84cab89c97d647b8a256fd08e33d9102810febd
ToppCell	mild_COVID-19_(asymptomatic)-gd_T\|World / disease group, cell group and cell class (v2)	IKZF2 SYNE1 ITGAD SPTBN4 CTSW PDZD2	7.18e-05	173	179	6	b6615ff02f5017d7150b1e33b53f8c7a26081a0d
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VSIG2 ESAM PCDH17 SPTBN4 ANKRD24 PDZD2	7.90e-05	176	179	6	27e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DSCAM PRXL2B ESAM YRDC PCDH17 HMCN2	7.90e-05	176	179	6	64e426f5e84884ce2c29acf6f4b958962a63927f
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IKZF2 SYNE1 AHNAK MARF1 MACF1 MX1	8.15e-05	177	179	6	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IKZF2 SYNE1 AHNAK MARF1 MACF1 MX1	8.15e-05	177	179	6	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	IKZF2 SYNE1 AHNAK MARF1 MACF1 MX1	8.15e-05	177	179	6	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IKZF2 SYNE1 AHNAK MARF1 MACF1 MX1	8.15e-05	177	179	6	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IKZF2 SYNE1 AHNAK MARF1 MACF1 MX1	8.15e-05	177	179	6	d5aeda113afaa2425874394610344570c9078478
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IKZF2 SYNE1 CASTOR2 AHNAK SLC7A5 CTSW	8.15e-05	177	179	6	84930899eb2978598bc8a351cbcd9e714e46799d
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	ZXDC COL6A3 PDK4 VWA7 DCTN1 ASL	8.40e-05	178	179	6	9a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ZNF536 KIF1A RALYL LINGO2 PCDH17 HSD17B2	8.67e-05	179	179	6	df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IKZF2 UPF1 FER1L6 SLC20A1 MACF1 RIMS1	8.67e-05	179	179	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 HTRA1 SCARF2 KIF26B EXTL1 PTPRN	8.94e-05	180	179	6	935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell	5'-Airway_Nasal-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 HTRA1 SCARF2 KIF26B EXTL1 PTPRN	8.94e-05	180	179	6	3dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM EID2 RAB44 TRIM3 PLXNB1 MX1	8.94e-05	180	179	6	be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM EID2 RAB44 TRIM3 PLXNB1 MX1	8.94e-05	180	179	6	3b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCell	facs-Heart-RA-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VSIG2 HIC2 DMKN RHOV HSD17B2 PLXNB1	9.21e-05	181	179	6	c68d272eb41f81bd8ea4d0360733a2396bc87037
ToppCell	facs-Heart-RA-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VSIG2 HIC2 DMKN RHOV HSD17B2 PLXNB1	9.21e-05	181	179	6	5e5eb89f224ee48065a328ade030cbc4dcdcac12
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PALD1 SYNE1 LAMA5 ESAM PCDH17 AJAP1	9.21e-05	181	179	6	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FLNB AARD ESAM PCDH17 TIMELESS TANGO6	9.21e-05	181	179	6	9cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB IGSF5 FER1L6 RHOV RIMS1 HSD17B2	9.49e-05	182	179	6	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	COVID-19_Mild-gd_T\|COVID-19_Mild / Disease condition and Cell class	IKZF2 SYNE1 AHNAK MACF1 SLC7A5 CTSW	9.78e-05	183	179	6	f593a89b0aa8fffdfa403769916facfd30358521
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 HTRA1 SCARF2 KIF26B EXTL1 PTPRN	9.78e-05	183	179	6	803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 HTRA1 SCARF2 KIF26B EXTL1 PTPRN	9.78e-05	183	179	6	6d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	IKZF2 SYNE1 AHNAK MARF1 MACF1 MX1	9.78e-05	183	179	6	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 HTRA1 SCARF2 KIF26B EXTL1 PTPRN	9.78e-05	183	179	6	cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF536 HTRA1 AARD PRXL2B ARID5A ZSCAN2	1.01e-04	184	179	6	a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	WHRN ZHX2 HERC6 CARNS1 MX1 TANGO6	1.01e-04	184	179	6	9cbfb9f09476b4d09eb8f92c6f21e449dabcfa98
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TPSAB1 IKZF2 RAB44 EXD3 ECHDC2 TPSB2	1.01e-04	184	179	6	ce31684772e47a294155f368e50b49753f7c8e87
Disease	malignant mesothelioma (is_marker_for)	HTRA1 ADA	3.34e-05	2	171	2	DOID:1790 (is_marker_for)
Disease	esophageal carcinoma (is_marker_for)	HTRA1 SLC7A5	9.98e-05	3	171	2	DOID:1107 (is_marker_for)
Disease	muscular dystrophy (is_implicated_in)	COL6A3 SYNE1 POMT1	1.22e-04	17	171	3	DOID:9884 (is_implicated_in)
Disease	synucleinopathy (biomarker_via_orthology)	KIF1A DCTN1	1.99e-04	4	171	2	DOID:0050890 (biomarker_via_orthology)
Disease	endothelial cell-selective adhesion molecule measurement	VSIG2 ESAM	4.93e-04	6	171	2	EFO_0008120
Disease	Autistic Disorder	KDM5B KIF1A ADA PASK NRXN2 C4B RIMS1	8.56e-04	261	171	7	C0004352
Disease	renal tubular acidosis (implicated_via_orthology)	ATP6V1B2 ATP6V0A1	9.14e-04	8	171	2	DOID:14219 (implicated_via_orthology)
Disease	tryptase beta-2 measurement	TPSAB1 TPSB2	1.17e-03	9	171	2	EFO_0008306
Disease	colon cancer (is_implicated_in)	HTRA1 ADA SLC7A5	1.19e-03	36	171	3	DOID:219 (is_implicated_in)
Disease	bipolar I disorder	SP4 SYNE1 PARP10 STARD9 ZSCAN2	1.41e-03	141	171	5	EFO_0009963
Disease	serum alanine aminotransferase measurement	WHRN LAMA5 LINGO2 ARHGAP39 RAB44 DCAF5 MPRIP USP21 NRXN2 NYNRIN AHNAK MARF1 MX1	1.73e-03	869	171	13	EFO_0004735
Disease	descending aortic diameter	FLNB COL6A3 SPTBN4 DISP2	1.74e-03	88	171	4	EFO_0021788
Disease	autism spectrum disorder (implicated_via_orthology)	KDM5B DSCAM NRXN2 SLC7A5 RIMS1	1.97e-03	152	171	5	DOID:0060041 (implicated_via_orthology)
Disease	motor neuron disease (implicated_via_orthology)	VWA1 DCTN1	2.12e-03	12	171	2	DOID:231 (implicated_via_orthology)
Disease	colorectal cancer (is_marker_for)	HTRA1 ASAP3 ADA FASN SLC7A5	2.26e-03	157	171	5	DOID:9256 (is_marker_for)
Disease	aspartate aminotransferase to alanine aminotransferase ratio	WHRN ARHGAP39 ADAM22 USP21 NYNRIN AHNAK	2.78e-03	239	171	6	EFO_0010934
Disease	Ischemic stroke	COL6A3 MC4R LINGO2 SYCE1L AJAP1 NYNRIN ZNF516	2.92e-03	324	171	7	HP_0002140
Disease	serum IgG glycosylation measurement	DSCAM VPS13C ABCF2 LINGO2 MPRIP SLC38A10 TTLL2 MDC1 MX1	3.58e-03	523	171	9	EFO_0005193
Disease	basophil measurement	TPSAB1 RAB44 TPSB2	5.14e-03	60	171	3	EFO_0803539
Disease	chronic lymphocytic leukemia	MC4R ZBTB7A KPNA7 FASN	5.16e-03	119	171	4	EFO_0000095
Disease	SARS-CoV-2 antibody measurement, response to COVID-19 vaccine	DSCAM LINGO2 ARRDC2	5.63e-03	62	171	3	EFO_0803360, EFO_0803362

Protein segments in the cluster

Peptide	Gene	Start	Entry
GPDQQGAGVDNVTLR	MAMDC4	626	Q6UXC1
VRLGEGGPDSDQAIR	FAM234A	526	Q9H0X4
DLDTRVALVGPNGAG	ABCF2	421	Q9UG63
VGGLRFEGPQVQDGR	B3GAT3	221	O94766
ERISQGLQGLPGRAE	AARD	11	Q4LEZ3
PDEVVALVGQGLQEG	ADA	126	P00813
AGGIPDVRGLQEAAL	C1orf167	31	Q5SNV9
EGLQAPGGSLREEAQ	ARID5A	316	Q03989
DRARVTGGIPGEVAQ	ASAP3	166	Q8TDY4
PGNGRVTQEDLVIGG	CYP27C1	416	Q4G0S4
LAGGEVPQDRVIDGQ	ARSL	421	P51690
RALQAAGAGQPVEGA	C2orf72	201	A6NCS6
SGIAGEEQQRGAIPG	DCTN1	1061	Q14203
GGLRQEAIDRFNAPG	CHD5	1076	Q8TDI0
VPGIHQLRDVGGEGV	CLPX	366	O76031
GGLAQQVLVPAGSAR	C4B	881	P0C0L5
VVIAEERLNAGLGPG	CPED1	126	A4D0V7
RTLQAPEGALGNVGA	ARID3C	36	A6NKF2
CGAGPQGEAAVRQAE	CARMIL2	746	Q6F5E8
PQEGNGLSARVDEGV	CARMIL2	1046	Q6F5E8
GQPLGFDECGIVAQI	CASTOR2	271	A6NHX0
VAGGAPEQQALLRRG	AJAP1	141	Q9UKB5
TNIGNIPRLGELDGE	ADAM22	606	Q9P0K1
VQDEGQGPGFEARVV	CAMTA2	671	O94983
GAGAVGVRLVEDAPQ	CARNS1	556	A5YM72
DLGGRGGVQVPAVDI	AHNAK	266	Q09666
QGLIRPALGNAGGVE	ARMC5	311	Q96C12
EVLLQGGAQPGITDA	ANKRD24	231	Q8TF21
DDTGQPVLERGQLNG	DISP2	1321	A7MBM2
EPVFSGGQAVAGRVL	ARRDC2	21	Q8TBH0
EEEGAVPLLGGALQR	AKAP8L	611	Q9ULX6
VVSPLLGGQQREGLA	RAD51D	211	O75771
AVAGENARVIAGQPL	RALYL	71	Q86SE5
PEEQGAGTVIGNIGR	PCDH17	26	O14917
RLEQGQAGPAVQEGL	RAB44	631	Q7Z6P3
DQRGLVQPGVDQRGL	QRICH2	691	Q9H0J4
DQRGLVQPGVDQRGL	QRICH2	701	Q9H0J4
ALNGDQTEGIFRVPG	ARHGAP39	921	Q9C0H5
VQAVDSGGPAERAGL	RGS3	321	P49796
NLQGLGPGVRVESLE	PALD1	191	Q9ULE6
AGSLNGAGLVPREVE	PDK4	11	Q16654
GQAGSGQRVPALEEA	ELOA2	286	Q8IYF1
AGRNPGGVVNVGADI	PTPRN	371	Q16849
AEGGQDPRINVVLAG	PASK	431	Q96RG2
GNIAGDGPEFRDNVI	KPNA7	181	A9QM74
IQQALAQERVGGVGP	MPRIP	551	Q6WCQ1
RGAGNGVVPAGVILE	MDC1	276	Q14676
QETGAGRANGEVLPT	LYSMD1	126	Q96S90
NGEVVVSLINGRPGA	LAMA3	226	Q16787
RQVAEAPGLVDVPGG	NUDT22	141	Q9BRQ3
ERDGQPVGAELGLQL	HMCN2	2301	Q8NDA2
GGAGVPNLAQRLEAL	KIF12	601	Q96FN5
SGAIAGNPLGVDREL	ASL	201	P04424
RFGVPVIADGGIQNV	IMPDH2	356	P12268
AGARGLQLRAGPEAE	KIF26B	1816	Q2KJY2
LQLRAGPEAEARGGA	KIF26B	1821	Q2KJY2
GGSEIQVRALAGPDQ	ECHDC2	26	Q86YB7
RLGGLASQEPGAIIE	MCM3AP	1596	O60318
SIQIGGLFPRGADQE	GRIA2	26	P42262
PLAREGAGGGEQLVD	FBXW8	86	Q8N3Y1
GPRGLVEPVNVVDNG	FLNB	1461	O75369
LNALLAVGPGAGEAQ	PLXNB1	1751	O43157
APAGEGEGVTLQRNI	SLC7A5P1	36	Q8MH63
GGDGPEQRLCQAAIQ	PDZD2	26	O15018
RSLEGIPLAQVAAGG	HERC6	176	Q8IVU3
RGLAEAQGAVGVAPF	NRXN2	671	Q9P2S2
ADPEAGGIGRVVNGA	DCAF5	311	Q96JK2
APAGEGEGVTLQRNI	SLC7A5	36	Q01650
EGNFEAVVQALRPAG	LRRC14B	166	A6NHZ5
DLAGNNIPGDVLRAV	LRRC45	206	Q96CN5
NNGAVVEGEVAGPRR	LINGO2	586	Q7L985
LQDVEGLQAGGRVPV	KDM5B	1021	Q9UGL1
ENGEIVVSLVNGRPG	LAMA5	226	O15230
VQELQGEGGIRLPNG	IKZF2	96	Q9UKS7
EAGLAPGELQQLAQG	NOC2L	721	Q9Y3T9
GPGGQRLNIDALQCD	NKD2	101	Q969F2
QLNEAAQGILTGPGD	MACF1	4636	Q9UPN3
VVNAGARNGLGAPVR	PUM1	566	Q14671
DGLGPAQLVGRQTLA	RIMS1	1521	Q86UR5
IDVAIGAPGEQENRG	ITGAD	536	Q13349
ERIQPGGRFEVVSQG	OBSCN	4661	Q5VST9
EQAPGALVGNVARAL	PCDHAC2	51	Q9Y5I4
RVAQLGAGQLPAVVA	NPC1L1	141	Q9UHC9
LEGGLARITQGQPLE	POMT1	306	Q9Y6A1
AGQLDAQVGPEGILQ	UPF1	71	Q92900
AQVGPEGILQNGAVD	UPF1	76	Q92900
GQLARIAGEAPGVVR	CPLANE2	156	Q9BU20
AGGVAVPTLNALERG	CNPPD1	151	Q9BV87
GSGNEVIEGPQNARV	IGSF5	36	Q9NSI5
PVIVLQRGACGQGQE	HTRA1	146	Q92743
NLEGGAGEVVRGRDP	DOCK8-AS1	26	Q5T8R8
TGVRQVPGFGVADAL	DMKN	81	Q6E0U4
ISPAGRELLVAGGNV	GGT6	111	Q6P531
IEELRQLGAASVGPG	C14orf93	156	Q9H972
RAGGSRVEEGVPQVL	COL6A3	336	P12111
QNDPEVIIVGAGVLG	SQLE	121	Q14534
GAGEGPGQQEALLLQ	C20orf141	106	Q9NUB4
AGLAQGIRGPLRAQD	CTSW	16	P56202
ANGDRDVPQAEVGRG	EID2	16	Q8N6I1
PANRLQAVEGGEVVL	ESAM	36	Q96AP7
GAVGGDVRILNPLDS	HAS1	261	Q92839
GDLEVVQENQGGVPL	MARF1	1036	Q9Y4F3
IAVLPGTGAIRQGAN	MC4R	226	P32245
VIAGNLGDLARIVGP	KIAA1210	106	Q9ULL0
PRQQGLGLAGEGEQA	E4F1	166	Q66K89
AVLGGERGGPEVQQV	FASN	471	P49327
GARGLIAEAAQLGPV	FASN	1951	P49327
IAEAAQLGPVGGVFN	FASN	1956	P49327
GDRLGNAGDVCVPQA	CCDC8	246	Q9H0W5
GPIVIGEGNLIEEQA	DCTN6	46	O00399
AGVLNENGPGAEELR	HSD17B2	111	P37059
GGNDVSNAIGPLVAL	SLC20A1	531	Q8WUM9
EGQLAPRDGVIIGLN	SLC38A10	1061	Q9HBR0
EGVLERQGAPPAAGQ	C1orf50	11	Q9BV19
GGLAQQVLVPAGSAR	C4A	881	P0C0L4
LRIVEGQGQGADVGP	KIF1A	941	Q12756
GVFAGVREQALGLEP	LIPE	336	Q05469
EPGNQGLRRVVIDGS	NYNRIN	786	Q9P2P1
GLVSLRPVGLQEQEG	PARP10	361	Q53GL7
DLGLQPQELADGGVR	PCDHGA1	51	Q9Y5H4
PQELADGGVRIVSRG	PCDHGA1	56	Q9Y5H4
LVLGEQIGRGNFGEV	FES	561	P07332
GAVATLPQREGAELG	DSCAM	1966	O60469
SVDRPQALIECGGQG	FER1L6	1011	Q2WGJ9
GEGVGDRVPNGILAS	HIC2	366	Q96JB3
VRLVGVGPEALGLQE	PRXL2B	66	Q8TBF2
GLQPIAEGQSEEGRA	RUSC1	416	Q9BVN2
LQLARARGQEGPGDV	RUSC2	1206	Q8N2Y8
VVGFEAEGRGLPQVR	PIF1	501	Q9H611
TGGPAVGAREQALAV	ATP6V1B2	21	P21281
LALPVINNVAAGGGT	SP4	266	Q02446
LQRVGIVGGQEAPRS	TPSAB1	26	Q15661
LQRVGIVGGQEAPRS	TPSB2	26	P20231
QVGIPVADEAGQRLG	SFXN3	201	Q9BWM7
AINVEGPVQGAQALG	SUPT20HL1	546	Q3ZLR7
IAQAQQGEGGLPDRG	SYNE1	1296	Q8NF91
SARLAILGGVEGQPA	ENTPD6	301	O75354
LPQEREGEGGLSLQV	MOV10	981	Q9HCE1
LTVAVGPLGRNLEGN	SH3YL1	126	Q96HL8
EIVDGGVPQAQLAGS	TELO2	471	Q9Y4R8
LGIAIEGGANTRQPL	WHRN	826	Q9P202
EAEPQGANVILEGLG	STARD9	3751	Q9P2P6
IFGEQVRSAPEVGAG	SYCE1L	201	A8MT33
NVRLVPTGLDFGQEG	NOP2	536	P46087
QPGVALLALEEERGG	EXTL1	221	Q92935
GLGPGERVEVQVLNI	SRBD1	966	Q8N5C6
PVGRREANLGTDAGV	EARS2	21	Q5JPH6
QIVLVEGGRTQDLPG	MRPS12	106	O15235
QGEVFLRRDGSIQGP	SLFNL1	341	Q499Z3
IIQAGQVQVLGGPDG	CNGB1	1001	Q14028
VQFGPLRGGEAQRVE	VWA1	366	Q6PCB0
PEQLAGVGQGRLAQE	TIMELESS	231	Q9UNS1
GAQENGRCQEAEIGP	TRAK2	851	O60296
GGDETPEGQRAVQAL	UGDH	181	O60701
GGPRANTVLERVEGA	TMEM9	146	Q9P0T7
RGDAALQAQPGVAGA	ZNF516	1021	Q92618
RQEVPGGGRAQELTE	USP21	246	Q9UK80
QEEVTRGPQGALGRL	ZSCAN2	66	Q7Z7L9
GVQVQLVQDDPSGEG	ZXDC	791	Q2QGD7
GIVGDAGVRGTAQQP	ATP6V0C	111	P27449
VNVLIQLDQGGREGP	RHOV	151	Q96L33
VAAGLRSVAQDPVGG	WDR97	106	A6NE52
LGRAEVALGAQGPRE	SCARF2	786	Q96GP6
PGEADSVLRGGSQVQ	SUGP2	196	Q8IX01
TGDLGDINAEQLPGR	PLAA	326	Q9Y263
PNGVQAVVRGILEGA	TANGO6	316	Q9C0B7
GASGAGPLVVALQVR	SPTBN4	841	Q9H254
QGAVQGPEEFAEGLV	VPS13C	3446	Q709C8
AGLGARLQEAGVSIP	TTLL2	41	Q9BWV7
ADGGEPQSVQVDGRA	TNXA	281	Q16473
GANVQARDDGGLIPL	TNKS2	81	Q9H2K2
GEEAGRSAGVQQPAL	ZNF536	726	O15090
LNFGGIRVGNGPTEE	ATP6V0A1	671	Q93050
GQDVGAPNGALSRLD	ZHX2	601	Q9Y6X8
LVVGGEAERPAGALQ	SNAPC4	1331	Q5SXM2
IDQVASLAGPGGQVE	TGS1	811	Q96RS0
EPSQGRVAGALIGVL	VSIG2	236	Q96IQ7
VILRGVPEGAELGQV	VWA7	656	Q9Y334
AGRETAVNGQGELIP	UHRF1BP1	996	Q6BDS2
EGLRNLGIPLGQDAE	SLC25A24	46	Q6NUK1
DVASPDGLGRLNVAG	ZBTB7A	546	O95365
QEVQGDGPFLDGINV	UBE3C	711	Q15386
VATGEGLRQALVGQP	TRIM3	326	O75382
IDGGQIGDGQSPECR	YRDC	221	Q86U90
DQQVVELIPGGAGIV	HECTD3	676	Q5T447
ELAENGGVLQLVGPE	KIAA1522	1006	Q9P206
GITRVAVGNQPADIG	MX1	181	P20591
ADGTRLQLAGVPVGV	EXD3	806	Q8N9H8