Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin protein ligase activity

RNF217 TRIM9 XIAP TRIM69 PJA1

4.43e-05372225GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RNF217 TRIM9 XIAP TRIM69 PJA1

6.11e-05398225GO:0061659
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

RNF217 TRIM9 XIAP TRIM69 PJA1

1.38e-04473225GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RNF217 TRIM9 XIAP TRIM69 PJA1

1.99e-04512225GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

RNF217 TRIM9 XIAP TRIM69 PJA1

2.38e-04532225GO:0016755
GeneOntologyMolecularFunctionlipid kinase activity

PIKFYVE DGKE

9.26e-0441222GO:0001727
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

DPYD NDUFS8

1.22e-0347222GO:0051539
GeneOntologyMolecularFunctionacyltransferase activity

RNF217 TRIM9 XIAP TRIM69 PJA1

1.32e-03775225GO:0016746
GeneOntologyMolecularFunctioniron-sulfur cluster binding

DPYD NDUFS8

3.31e-0378222GO:0051536
GeneOntologyMolecularFunctionmetal cluster binding

DPYD NDUFS8

3.74e-0383222GO:0051540
DomainFer4

DPYD NDUFS8

3.97e-063222PF00037
Domain4Fe4S_Fe_S_CS

DPYD NDUFS8

7.94e-064222IPR017900
Domain4FE4S_FER_1

DPYD NDUFS8

7.94e-064222PS00198
DomainHelical_ferredxn

DPYD NDUFS8

1.32e-055222IPR009051
Domain4Fe4S_Fe-S-bd

DPYD NDUFS8

1.32e-055222IPR017896
Domain4FE4S_FER_2

DPYD NDUFS8

1.32e-055222PS51379
DomainZF_RING_1

RNF217 TRIM9 XIAP TRIM69 PJA1

1.88e-05291225PS00518
DomainTesmin/TSO1-like_CXC

EZH1 LIN54

1.98e-056222IPR033467
DomainCXC

EZH1 LIN54

1.98e-056222SM01114
DomainZF_RING_2

RNF217 TRIM9 XIAP TRIM69 PJA1

2.11e-05298225PS50089
DomainZnf_RING/FYVE/PHD

PIKFYVE TRIM9 XIAP TRIM69 PJA1

1.63e-04459225IPR013083
DomainRING

TRIM9 XIAP TRIM69 PJA1

4.04e-04305224SM00184
DomainVWC

CCN4 BMPER

4.91e-0428222PF00093
DomainZnf_RING

TRIM9 XIAP TRIM69 PJA1

5.20e-04326224IPR001841
DomainVWFC_1

CCN4 BMPER

8.14e-0436222PS01208
DomainVWC

CCN4 BMPER

9.08e-0438222SM00214
DomainVWFC_2

CCN4 BMPER

9.08e-0438222PS50184
DomainZnf_C3HC4_RING-type

TRIM9 TRIM69 PJA1

1.04e-03172223IPR018957
DomainVWF_dom

CCN4 BMPER

1.11e-0342222IPR001007
Domain-

PIKFYVE TRIM9 TRIM69 PJA1

1.71e-034492243.30.40.10
Domainzf-C3HC4

TRIM9 TRIM69 PJA1

2.19e-03223223PF00097
Domain-

TRIM9 TRIM69

3.13e-03712224.10.45.10
DomainZnf_B-box

TRIM9 TRIM69

4.06e-0381222IPR000315
DomainSPRY

TRIM9 TRIM69

4.66e-0387222SM00449
DomainSPRY

TRIM9 TRIM69

5.42e-0394222PF00622
DomainSPRY_dom

TRIM9 TRIM69

5.42e-0394222IPR003877
DomainB30.2/SPRY

TRIM9 TRIM69

5.53e-0395222IPR001870
DomainB302_SPRY

TRIM9 TRIM69

5.53e-0395222PS50188
Pubmed

Effects of depletion of dihydropyrimidine dehydrogenase on focus formation and RPA phosphorylation.

RPA1 DPYD

3.82e-07222222510597
Pubmed

E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.

XIAP TRIM69

2.51e-051222235794827
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

RPA1 CCN4 DOCK11 TRIM9 LAMB3

8.18e-0573622529676528
Pubmed

MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.

EZH1 RPA1 XIAP

9.30e-0514022320819778
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PIKFYVE BRIX1 RPA1 XIAP DGKE NDUFS8

2.58e-04149622632877691
Pubmed

The tripartite motif family identifies cell compartments.

TRIM9 TRIM69

3.09e-044122211331580
Pubmed

A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation.

BRIX1 FCF1

4.06e-044722232160526
Pubmed

A protein interaction landscape of breast cancer.

EZH1 BRIX1 RPA1 LAMB3

6.16e-0463422434591612
GeneFamilyRing finger proteins

RNF217 TRIM9 TRIM69 PJA1

8.25e-0527516458
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM9 TRIM69

3.12e-039516259
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN4 ADAM28 PJA1

5.23e-05149223aedbae2dffa1e880e5c6a146b6d5a135e7f54308
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

PIKFYVE ADAM28 ZNF560

6.71e-0516222391ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRIM9 ADAM28 BMPER

8.29e-05174223f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellcellseq-Epithelial-Epithelial_Glandular-MEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TRIM9 LAMB3 WFDC8

9.94e-051852230595e7ab37eed690f6e3d16a9a4e9a4bce2b89db
ToppCellcellseq-Epithelial-Epithelial_Glandular-MEC-MEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TRIM9 LAMB3 WFDC8

9.94e-0518522376304829fcfb5934188933ca20d33bc8c8b0dc91
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN4 DGKE BMPER

1.01e-0418622337860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN4 DGKE BMPER

1.01e-04186223baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN4 DGKE BMPER

1.01e-0418622360830822d3de3147816693404fd03392e04c2b8e
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

CCN4 TRIM9 BMPER

1.03e-04187223e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

PIKFYVE RUBCN ADAM28

1.08e-041902231e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellLV-08._Macrophage|World / Chamber and Cluster_Paper

DOCK11 DPYD ADAM28

1.09e-04191223e7a0bc46ba9ba772636a583f3387748418e18832
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

DOCK11 DPYD ADAM28

1.11e-04192223a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

DOCK11 DPYD ADAM28

1.11e-041922237be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

DOCK11 DPYD ADAM28

1.13e-0419322312bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIKFYVE RUBCN ADAM28

1.14e-041942235cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

DOCK11 DPYD ADAM28

1.14e-04194223c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

DOCK11 DPYD ADAM28

1.14e-04194223ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WFDC8 BMPER PJA1

1.16e-041952234a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WFDC8 BMPER PJA1

1.16e-041952237a32a8535c29b819dacba901d0658280a2631c94
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN4 ADAM28 BMPER

1.18e-041962232ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM28 BMPER PJA1

1.18e-04196223a7adc0e0baef261d0937e4e8351321d41beca82f
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM28 BMPER PJA1

1.20e-04197223236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN4 ADAM28 PJA1

1.20e-04197223ad6c200a193a15360d17463e18a465ce1b90b8da
ToppCellBronchus_Control_(B.)-Stromal-TX-Mesothelial-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CCN4 TRIM9 BMPER

1.23e-0419922360a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN4 ADAM28 PJA1

1.25e-042002233dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Npnt_(Retrosplenial_areas,_layer_5,_Npnt+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ADAM28 WFDC8

1.85e-0441222b1e70962de91a747ec718a3fad4247fd0cb7d9a8
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Npnt_(Retrosplenial_areas,_layer_5,_Npnt+)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ADAM28 WFDC8

1.85e-044122216dbb13baa47c4db80ddd83ac36aad6c43b5461a
Diseaseanxiety measurement

FCF1 DPYD

2.66e-03108212EFO_0009863

Protein segments in the cluster

PeptideGeneStartEntry
ECCEKCQFKKAGMVC

ADAM28

451

Q9UKQ2
VCEMKNCNKCIYFEA

BRIX1

106

Q8TDN6
EMCINCGKCYMTCND

DPYD

951

Q12882
YQPKYCGVCMDNRCC

CCN4

296

O95388
CLKNYCECYEAKIMC

LIN54

606

Q6MZP7
CECYEAKIMCSSICK

LIN54

611

Q6MZP7
DMTKCIYCGFCQEAC

NDUFS8

146

O00217
CMYQACPTQDCNKKV

RPA1

476

P27694
MPDSQCKECYDCSEK

PIKFYVE

156

Q9Y2I7
TDMCECPVHKNCYCE

BMPER

586

Q8N8U9
VNMCAAFCYEVLKCC

DOCK11

1476

Q5JSL3
MDCLYAKCIPCITDC

FCF1

91

Q9Y324
CTQYGEWQMKCCKCD

LAMB3

56

Q13751
NVPLCSYCMVCKQQC

DGKE

131

P52429
SYCMVCKQQCGCQPK

DGKE

136

P52429
CMLCQAKGFICEFCQ

RUBCN

881

Q92622
PCCKKAVCEECLKVY

RNF217

276

Q8TC41
TFCPECKMLCQYNNC

TRIM69

76

Q86WT6
QKCCFFACQKKCMDP

WFDC8

76

Q8IUA0
CKQCAEAVDKCPMCY

XIAP

471

P98170
PCIMTQNFCEKFCQC

EZH1

536

Q92800
CVQCKMPVCYQCLEE

TRIM9

241

Q9C026
QEMCCPICCSEYVKG

PJA1

591

Q8NG27
CKQCEDVFCKHPCLK

ZNF560

216

Q96MR9