Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontoxic substance binding

EPHX2 CHRFAM7A CHRNA7

6.65e-0518893GO:0015643
GeneOntologyMolecularFunctionsulfotransferase activity

TPST1 SULT1A4 SULT1A3 CHST8

1.06e-0455894GO:0008146
GeneOntologyMolecularFunctiontyrosine-ester sulfotransferase activity

SULT1A4 SULT1A3

1.17e-044892GO:0017067
GeneOntologyMolecularFunctionamine sulfotransferase activity

SULT1A4 SULT1A3

1.17e-044892GO:0047685
GeneOntologyMolecularFunctionflavonol 3-sulfotransferase activity

SULT1A4 SULT1A3

1.95e-045892GO:0047894
GeneOntologyMolecularFunctiontransferase activity, transferring sulphur-containing groups

TPST1 SULT1A4 SULT1A3 CHST8

3.34e-0474894GO:0016782
GeneOntologyMolecularFunctionsteroid sulfotransferase activity

SULT1A4 SULT1A3

4.07e-047892GO:0050294
GeneOntologyMolecularFunctionsulfate binding

SULT1A4 SULT1A3

6.93e-049892GO:0043199
GeneOntologyMolecularFunctionaryl sulfotransferase activity

SULT1A4 SULT1A3

8.64e-0410892GO:0004062
GeneOntologyMolecularFunctionneurotransmitter receptor activity

PTK2B GRM1 CHRFAM7A CHRNA7

1.04e-03100894GO:0030594
GeneOntologyMolecularFunctionacetylcholine binding

CHRFAM7A CHRNA7

1.48e-0313892GO:0042166
GeneOntologyMolecularFunction3'-phosphoadenosine 5'-phosphosulfate binding

SULT1A4 SULT1A3

1.48e-0313892GO:0050656
GeneOntologyBiologicalProcesspositive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

CHRFAM7A CHRNA7

1.76e-052872GO:0001988
GeneOntologyBiologicalProcess3'-phosphoadenosine 5'-phosphosulfate metabolic process

TPST1 SULT1A4 SULT1A3

4.72e-0517873GO:0050427
GeneOntologyBiologicalProcesspurine ribonucleoside bisphosphate metabolic process

TPST1 SULT1A4 SULT1A3

4.72e-0517873GO:0034035
GeneOntologyBiologicalProcessbaroreceptor response to decreased systemic arterial blood pressure

CHRFAM7A CHRNA7

5.26e-053872GO:0001982
GeneOntologyBiologicalProcessregulation of nervous system process

PTK2B RNF10 GRM1 CHRFAM7A TNFRSF21 CHRNA7

9.79e-05175876GO:0031644
GeneOntologyBiologicalProcessgeneration of ovulation cycle rhythm

CHRFAM7A CHRNA7

1.05e-044872GO:0060112
GeneOntologyBiologicalProcesssensory processing

CHRFAM7A CHRNA7

1.74e-045872GO:0050893
GeneOntologyBiologicalProcess4-nitrophenol metabolic process

SULT1A4 SULT1A3

1.74e-045872GO:0018960
GeneOntologyBiologicalProcessregulation of norepinephrine secretion

PLCD1 CHRFAM7A CHRNA7

1.76e-0426873GO:0014061
GeneOntologyBiologicalProcesssulfation

TPST1 SULT1A4 SULT1A3

1.97e-0427873GO:0051923
GeneOntologyBiologicalProcesspostsynaptic signal transduction

CAMK4 RNF10 CHRFAM7A CHRNA7

2.07e-0469874GO:0098926
GeneOntologyBiologicalProcessnorepinephrine secretion

PLCD1 CHRFAM7A CHRNA7

2.20e-0428873GO:0048243
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback

CHRFAM7A CHRNA7

2.61e-046872GO:0001978
GeneOntologyBiologicalProcessnucleoside bisphosphate metabolic process

TPST1 ACOT8 SULT1A4 SULT1A3 KYNU

3.38e-04142875GO:0033865
GeneOntologyBiologicalProcessribonucleoside bisphosphate metabolic process

TPST1 ACOT8 SULT1A4 SULT1A3 KYNU

3.38e-04142875GO:0033875
GeneOntologyBiologicalProcesspurine nucleoside bisphosphate metabolic process

TPST1 ACOT8 SULT1A4 SULT1A3 KYNU

3.38e-04142875GO:0034032
GeneOntologyCellularComponentspine apparatus membrane

CHRFAM7A CHRNA7

5.24e-053882GO:0098897
GeneOntologyCellularComponentcholinergic synapse

PLD1 CHRFAM7A CHRNA7

1.05e-0422883GO:0098981
MousePhenoairway basal cell hyperplasia

CHRFAM7A CHRNA7

2.40e-052692MP:0011115
MousePhenoabnormal airway basal cell differentiation

CHRFAM7A CHRNA7

2.40e-052692MP:0011114
MousePhenoabnormal airway basal cell morphology

CHRFAM7A CHRNA7

2.40e-052692MP:0011113
MousePhenoabnormal parietal lobe morphology

ATP7B PLXNA4 CHRFAM7A CHRNA7

3.18e-0537694MP:0000794
MousePhenoabnormal nicotine-mediated receptor currents

CHRFAM7A CHRNA7

1.43e-044692MP:0009475
Domain-

CKS1B CKS2

2.25e-0528923.30.170.10
DomainCyclin-dep_kinase_reg-sub

CKS1B CKS2

2.25e-052892IPR000789
DomainCKS_1

CKS1B CKS2

2.25e-052892PS00944
DomainCKS_2

CKS1B CKS2

2.25e-052892PS00945
DomainCKS

CKS1B CKS2

2.25e-052892SM01084
DomainCKS

CKS1B CKS2

2.25e-052892PF01111
Pubmed

Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.

CHRFAM7A CHRNA7

6.77e-06291238070724
Pubmed

Inflammatory cytokines decrease the expression of nicotinic acetylcholine receptor during the cell maturation.

CHRFAM7A CHRNA7

6.77e-06291219626424
Pubmed

Episodic memory performance predicted by the 2bp deletion in exon 6 of the "alpha 7-like" nicotinic receptor subunit gene.

CHRFAM7A CHRNA7

6.77e-06291217012698
Pubmed

Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke.

CHRFAM7A CHRNA7

6.77e-06291226451017
Pubmed

Wide-spread enhancer effect of SNP rs2279590 on regulating epoxide hydrolase-2 and protein tyrosine kinase 2-beta gene expression.

EPHX2 PTK2B

6.77e-06291236470481
Pubmed

Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.

CHRFAM7A CHRNA7

6.77e-06291234453977
Pubmed

Perinatal hypoxia-ischemia reduces α 7 nicotinic receptor expression and selective α 7 nicotinic receptor stimulation suppresses inflammation and promotes microglial Mox phenotype.

CHRFAM7A CHRNA7

6.77e-06291224757672
Pubmed

Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

CHRFAM7A CHRNA7

6.77e-06291226999808
Pubmed

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.

CHRFAM7A CHRNA7

6.77e-06291227129924
Pubmed

Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in alpha7 nicotinic receptor knockout mice.

CHRFAM7A CHRNA7

6.77e-06291217291692
Pubmed

Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.

CHRFAM7A CHRNA7

6.77e-06291223521765
Pubmed

Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.

CHRFAM7A CHRNA7

6.77e-06291228258105
Pubmed

The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.

CHRFAM7A CHRNA7

6.77e-06291219344760
Pubmed

Loss of α7nAChR enhances endothelial-to-mesenchymal transition after myocardial infarction via NF-κB activation.

CHRFAM7A CHRNA7

6.77e-06291235926661
Pubmed

The alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice.

CHRFAM7A CHRNA7

6.77e-06291217640819
Pubmed

Clinical significance and expression of cyclin kinase subunits 1 and 2 in hepatocellular carcinoma.

CKS1B CKS2

6.77e-06291219845855
Pubmed

Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure.

CHRFAM7A CHRNA7

6.77e-06291223431157
Pubmed

Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.

CHRFAM7A CHRNA7

6.77e-06291229114104
Pubmed

Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.

CHRFAM7A CHRNA7

6.77e-06291233995108
Pubmed

E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.

CHRFAM7A CHRNA7

6.77e-06291232552811
Pubmed

Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.

CHRFAM7A CHRNA7

6.77e-06291224836856
Pubmed

Modulation of the MAPKs pathways affects Aβ-induced cognitive deficits in Alzheimer's disease via activation of α7nAChR.

CHRFAM7A CHRNA7

6.77e-06291231904546
Pubmed

Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.

CHRFAM7A CHRNA7

6.77e-06291215948184
Pubmed

Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.

CHRFAM7A CHRNA7

6.77e-06291235678315
Pubmed

Age-Associated Tooth Loss and Oral Microbial Dysbiosis in a Mouse Genetic Model of Chronic Nicotine Exposure.

CHRFAM7A CHRNA7

6.77e-06291233117372
Pubmed

Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.

CHRFAM7A CHRNA7

6.77e-06291212628457
Pubmed

Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.

CHRFAM7A CHRNA7

6.77e-06291225157794
Pubmed

Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes.

CHRFAM7A CHRNA7

6.77e-06291219615981
Pubmed

Splenic nerve denervation attenuates depression-like behaviors in Chrna7 knock-out mice via the spleen-gut-brain axis.

CHRFAM7A CHRNA7

6.77e-06291238944290
Pubmed

Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice.

CHRFAM7A CHRNA7

6.77e-06291228243714
Pubmed

Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.

CHRFAM7A CHRNA7

6.77e-06291231202708
Pubmed

Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.

CHRFAM7A CHRNA7

6.77e-06291222246862
Pubmed

Stimulation of the α7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation.

CHRFAM7A CHRNA7

6.77e-06291224298024
Pubmed

Lung eosinophilia induced by house dust mites or ovalbumin is modulated by nicotinic receptor α7 and inhibited by cigarette smoke.

CHRFAM7A CHRNA7

6.77e-06291229975102
Pubmed

α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile Duct-Ligated Mice.

CHRFAM7A CHRNA7

6.77e-06291229580318
Pubmed

Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis.

CHRFAM7A CHRNA7

6.77e-06291235479080
Pubmed

[Activation of α7 nAChR improves white fat homeostasis and promotes beige adipogenesis and thermogenesis in obese mice].

CHRFAM7A CHRNA7

6.77e-06291238597441
Pubmed

Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.

CHRFAM7A CHRNA7

6.77e-06291227471776
Pubmed

Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.

CHRFAM7A CHRNA7

6.77e-06291222688057
Pubmed

α7 Nicotinic acetylcholine receptor agonist attenuates neuropathological changes associated with intracerebral hemorrhage in mice.

CHRFAM7A CHRNA7

6.77e-06291222820264
Pubmed

Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis.

CHRFAM7A CHRNA7

6.77e-06291233953172
Pubmed

Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.

CHRFAM7A CHRNA7

6.77e-06291232028688
Pubmed

Genetic variation in CHRNA7 and CHRFAM7A is associated with nicotine dependence and response to varenicline treatment.

CHRFAM7A CHRNA7

6.77e-06291230089821
Pubmed

Nicotinic acetylcholine receptor activation reduces skeletal muscle inflammation of mdx mice.

CHRFAM7A CHRNA7

6.77e-06291220615555
Pubmed

Nicotine physical dependence in the mouse: involvement of the alpha7 nicotinic receptor subtype.

CHRFAM7A CHRNA7

6.77e-06291215896732
Pubmed

Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.

CHRFAM7A CHRNA7

6.77e-06291230429582
Pubmed

A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.

CHRFAM7A CHRNA7

6.77e-06291221501254
Pubmed

α7-cholinergic receptor mediates vagal induction of splenic norepinephrine.

CHRFAM7A CHRNA7

6.77e-06291221339364
Pubmed

Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.

CHRFAM7A CHRNA7

6.77e-06291221368056
Pubmed

Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice.

CHRFAM7A CHRNA7

6.77e-06291224289814
Pubmed

Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury.

CHRFAM7A CHRNA7

6.77e-06291219949071
Pubmed

Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.

CHRFAM7A CHRNA7

6.77e-0629121400473
Pubmed

Reversible inhibition of GABAA receptors by alpha7-containing nicotinic receptors on the vertebrate postsynaptic neurons.

CHRFAM7A CHRNA7

6.77e-06291217204496
Pubmed

Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.

CHRFAM7A CHRNA7

6.77e-06291226937017
Pubmed

α7 nicotinic receptors play a role in regulation of cardiac hemodynamics.

CHRFAM7A CHRNA7

6.77e-06291237017608
Pubmed

Impaired hippocampal theta oscillations in the mice null alpha7 nicotinic acetylcholine receptors.

CHRFAM7A CHRNA7

6.77e-06291223795917
Pubmed

Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.

CHRFAM7A CHRNA7

6.77e-06291236603528
Pubmed

Endogenous signaling through alpha7-containing nicotinic receptors promotes maturation and integration of adult-born neurons in the hippocampus.

CHRFAM7A CHRNA7

6.77e-06291220592195
Pubmed

Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.

CHRFAM7A CHRNA7

6.77e-06291226650489
Pubmed

Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation.

CHRFAM7A CHRNA7

6.77e-06291211854451
Pubmed

Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.

CHRFAM7A CHRNA7

6.77e-06291222848433
Pubmed

Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation.

CHRFAM7A CHRNA7

6.77e-06291223842742
Pubmed

Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors.

CHRFAM7A CHRNA7

6.77e-06291217292512
Pubmed

Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.

CHRFAM7A CHRNA7

6.77e-06291216650968
Pubmed

Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.

CHRFAM7A CHRNA7

6.77e-06291235413868
Pubmed

Circulating brain microvascular endothelial cells (cBMECs) as potential biomarkers of the blood-brain barrier disorders caused by microbial and non-microbial factors.

CHRFAM7A CHRNA7

6.77e-06291223637989
Pubmed

Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7).

CHRFAM7A CHRNA7

6.77e-0629129782083
Pubmed

Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.

CHRFAM7A CHRNA7

6.77e-06291224462939
Pubmed

Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.

CHRFAM7A CHRNA7

6.77e-06291229261717
Pubmed

Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.

CHRFAM7A CHRNA7

6.77e-06291218199426
Pubmed

Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.

CHRFAM7A CHRNA7

6.77e-06291222490926
Pubmed

Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.

CHRFAM7A CHRNA7

6.77e-06291236997969
Pubmed

A phenotype for the alpha 7 nicotinic acetylcholine receptor null mutant.

CHRFAM7A CHRNA7

6.77e-06291215364017
Pubmed

Choline, an alpha7 nicotinic acetylcholine receptor agonist, alleviates hyperalgesia in a rat osteoarthritis model.

CHRFAM7A CHRNA7

6.77e-06291223769729
Pubmed

Mice deficient in CHRNA7, a subunit of the nicotinic acetylcholine receptor, produce sperm with impaired motility.

CHRFAM7A CHRNA7

6.77e-06291215944242
Pubmed

Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.

CHRFAM7A CHRNA7

6.77e-06291223270857
Pubmed

Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.

CHRFAM7A CHRNA7

6.77e-06291218077004
Pubmed

Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.

CHRFAM7A CHRNA7

6.77e-06291219462340
Pubmed

Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.

CHRFAM7A CHRNA7

6.77e-06291216923147
Pubmed

NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.

CHRFAM7A CHRNA7

6.77e-06291211790782
Pubmed

A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression-like phenotypes.

CHRFAM7A CHRNA7

6.77e-06291233422641
Pubmed

Nicotinic ACh receptor α7 inhibits PDGF-induced migration of vascular smooth muscle cells by activating mitochondrial deacetylase sirtuin 3.

CHRFAM7A CHRNA7

6.77e-06291230270436
Pubmed

Activation of α-7 Nicotinic Acetylcholine Receptor Attenuates Cardiac Inflammation Through NLRP3/Caspase-1/IL-18 Pathway.

CHRFAM7A CHRNA7

6.77e-06291234988776
Pubmed

Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.

CHRFAM7A CHRNA7

6.77e-06291237746145
Pubmed

A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.

CHRFAM7A CHRNA7

6.77e-06291219631623
Pubmed

Crystal structure of human catecholamine sulfotransferase.

SULT1A4 SULT1A3

6.77e-06291210543947
Pubmed

Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.

CHRFAM7A CHRNA7

6.77e-06291215770102
Pubmed

Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.

CHRFAM7A CHRNA7

6.77e-06291224326163
Pubmed

Loss of α7 nicotinic acetylcholine receptors in GABAergic neurons causes sex-dependent decreases in radial glia-like cell quantity and impairments in cognitive and social behavior.

CHRFAM7A CHRNA7

6.77e-06291233398432
Pubmed

Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.

CHRFAM7A CHRNA7

6.77e-06291223811428
Pubmed

beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts.

CHRFAM7A CHRNA7

6.77e-06291220374280
Pubmed

Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice.

CHRFAM7A CHRNA7

6.77e-06291238185761
Pubmed

Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.

CHRFAM7A CHRNA7

6.77e-06291220720594
Pubmed

α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation.

CHRFAM7A CHRNA7

6.77e-06291222624500
Pubmed

Involvement of acetylcholine-α7nAChR in the protective effects of arterial baroreflex against ischemic stroke.

CHRFAM7A CHRNA7

6.77e-06291223106973
Pubmed

Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107.

CHRFAM7A CHRNA7

6.77e-06291233902624
Pubmed

Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task.

CHRFAM7A CHRNA7

6.77e-06291217019565
Pubmed

Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting alpha7 nicotinic ACh receptors.

CHRFAM7A CHRNA7

6.77e-06291219100751
Pubmed

Identification of an alternatively processed nicotinic receptor alpha7 subunit RNA in mouse brain.

CHRFAM7A CHRNA7

6.77e-06291214499477
Pubmed

Multiple calcium channels and kinases mediate alpha7 nicotinic receptor neuroprotection in PC12 cells.

CHRFAM7A CHRNA7

6.77e-06291215969741
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

PTK2B MYO7A FARP1

4.98e-04505631293
GeneFamilySulfotransferases, cytosolic

SULT1A4 SULT1A3

8.37e-0414562762
GeneFamilySulfotransferases, membrane bound

TPST1 CHST8

5.85e-0337562763
GeneFamilyAnkyrin repeat domain containing

ANKRD20A4P ASB9 ESPNL ANKRD20A1

6.67e-03242564403
GeneFamilyPhospholipases

PLCD1 PLD1

7.49e-0342562467
CoexpressionLE_EGR2_TARGETS_UP

CKS1B CKS2 TENM3 TNC POU3F1 TNFRSF21

2.11e-06109906MM1148
CoexpressionLE_EGR2_TARGETS_UP

CKS1B CKS2 TENM3 TNC POU3F1 TNFRSF21

2.23e-06110906M12804
CoexpressionKANG_IMMORTALIZED_BY_TERT_UP

CKS1B NRCAM HPD TNC ITGA3

1.34e-0588905M5360
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A TCAIM NRCAM CFAP221 PLXNA4 GRM1

9.56e-0716091603b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZFHX4 TENM3 WFS1 MPDZ LRRC70 PKHD1L1

2.02e-0618291653c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CKS2 PDE3A CILP2 ENTPD3 CHRFAM7A CHRNA7

2.22e-0618591679cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.52e-06189916a153b83314cf52808f685296cff8c95af3f4983d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ST8SIA1 ABCA9

2.59e-061909162306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.59e-0619091645df8fee00f8949937863159d7aa042e72748d9b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ST8SIA1 ABCA9

2.59e-061909161f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHX2 SDSL FRZB PLXNA4 PKHD1L1 S100PBP

2.59e-061909163cf464664d6aa22b212e60b70885953887e92483
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ST8SIA1 ABCA9

2.67e-06191916a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.67e-06191916b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.75e-061929166f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.75e-06192916dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.75e-06192916162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.75e-061929163d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.75e-061929164e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPST1 NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.75e-06192916ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.75e-06192916deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.84e-06193916fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellcritical-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TGFB1I1 NRCAM FARP1 FRZB MPDZ ABCA9

2.84e-061939166be11fef87af04ee7a3cc223882ccd4077caded9
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.92e-0619491660622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A NRCAM TENM3 TNC PLXNA4 ST8SIA1

2.92e-0619491689b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ST8SIA1 ABCA9

3.01e-06195916d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ZFHX4 TENM3 TNC CAMK4 ABCA9

3.01e-06195916cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ZFHX4 TENM3 TNC CAMK4 ABCA9

3.01e-06195916783bfa8110161cbd6def50ce849cae676c39c458
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A ZFHX4 TENM3 TNC RXFP1 ABCA9

3.01e-061959163d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ST8SIA1 ABCA9

3.10e-06196916a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ST8SIA1 ABCA9

3.10e-061969163e6803587d8566fd08cb8b290be3b6461743d79c
ToppCelldistal-Endothelial-Lymphatic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZFHX4 MYO7A WFS1 LRRC70 PKHD1L1 CHST8

3.10e-06196916b0f23dc802a2c2a56a08d398a464ea78b58ade4c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ST8SIA1 ABCA9

3.19e-061979166d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ST8SIA1 ABCA9

3.19e-06197916b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellMS-CD4-naive_CD4|MS / Condition, Cell_class and T cell subcluster

EPHX2 LINS1 TMEM45B CAMK4 ST8SIA1 SARDH

3.19e-06197916eb0d4849de4ca374bd9c1e138d4f2b9c19227b15
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ST8SIA1 ABCA9

3.19e-06197916c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCelldistal-1-Endothelial-Lymphatic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZFHX4 MYO7A WFS1 LRRC70 PKHD1L1 CHST8

3.29e-06198916b6fea363463c8dd7e6780c085ece4900266a6286
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3A CILP2 ZFHX4 TENM3 TNC ABCA9

3.48e-06200916a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCelldroplet-Skin-nan-21m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPST1 NRCAM CAMK4 FARP1 FAM171B SARDH

3.48e-0620091669295705fc614c2687f2b6c8e6aa0c6717841008
ToppCellAT2_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

SULT1A4 ANKRD20A4P NRCAM TNC LRRC70

7.37e-06131915ff4e618bd944f852bbd34438f740187aca82460f
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTK2B ZFHX4 WFS1 FRZB POU3F1

1.33e-05148915d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPHX2 TENM3 ENTPD3 VASH2 ANKRD20A1

1.88e-0515991522427ad4ad2e797e4664e7a7b0514094f22a18b2
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTK2B ZFHX4 CAMK4 FRZB POU3F1

1.88e-05159915a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDE3A TCAIM FRZB RXFP1 S100PBP

2.00e-051619159703b7e67d9fadb6129cad166bd01be915042e44
ToppCellBL-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TGFB1I1 PDE3A TEX30 UNC13D CHRFAM7A

2.06e-0516291525ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 PLXNA4 RXFP1 ABCA9

2.52e-05169915a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

EPHX2 VASH2 ST8SIA1 ITGA3 CHRNA7

2.60e-05170915513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CILP2 TENM3 TNC FRZB WRAP73

2.67e-05171915d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPHX2 PDE3A TCAIM PLD1 STAT5A

2.75e-051729158a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO7A WFS1 ASGR1 MPDZ PKHD1L1

2.82e-051739157dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CKS2 PDE3A ENTPD3 CHRFAM7A CHRNA7

3.24e-05178915e86ed30652c2de70f16430f04b78789b87df4af2
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTK2B TENM3 PLXNA4 GRM1 CHST8

3.32e-05179915747a32460b257fffca30527b56a74720eb9c12e4
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PDE3A ANKRD20A4P ZFHX4 FRZB TNFRSF21

3.50e-051819157e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCellwk_15-18-Epithelial-PNS-intermediate_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ANKRD20A4P TENM3 TNC POU3F1 ANKRD20A1

3.69e-05183915d874aa9a856f79626c8a8371f6196a77b7d662ee
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTK2B PLXNA4 RXFP1 GRM1 CHST8

3.79e-051849159a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHX2 SDSL ASGR1 ITGA3 CDH16

3.79e-0518491561caaa31975e05c9a6512079c791fed5a9e2d39f
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TGFB1I1 TBXAS1 PDE3A PLXNA4 PKHD1L1

3.79e-05184915ba65e3972b2b8d825a2c1a9d03d092cc1afad073
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHX2 SDSL ASGR1 ITGA3 CDH16

3.79e-0518491503da0f0f89f1ca5a3ccca1e22972f3129464e68e
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHX2 SDSL ASGR1 ITGA3 CDH16

3.79e-051849159ed2a65a4ca0ebbbb89ace61027522f93369843d
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TENM3 WFS1 LRRC70 GRM1 PKHD1L1

3.79e-05184915e5756afa3181186f9b65552b8df5359ef4024bee
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A ENTPD3 METAP1D CHRFAM7A CHRNA7

3.89e-05185915cefd81adb480c027545a5c78dcd05669783717f4
ToppCellfacs-Trachea-nan-24m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX2 SDSL ASGR1 ITGA3 CDH16

3.89e-05185915e502ec54971f518d0cf1b619b745607a8ab5ddf3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TBXAS1 TENM3 TNC CAMK4 ST8SIA1

3.99e-051869154d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A ENTPD3 METAP1D CHRFAM7A CHRNA7

4.09e-05187915ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A ZFHX4 TENM3 RXFP1 ABCA9

4.09e-0518791576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM3 TNC FRZB ITGA3 CHST8

4.09e-05187915806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A CILP2 ENTPD3 CHRFAM7A CHRNA7

4.09e-05187915d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Slc17a6-Inhibitory_Neuron.Slc17a6-Gad1Gad2.Asb4_(Periventricular_Fiber_System_(Pv))|Thalamus / BrainAtlas - Mouse McCarroll V32

DPYS AIPL1 RSPH6A KYNU

4.15e-059491482e9178c848468497295c4cc59c662b9279208a1
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Slc17a6-Inhibitory_Neuron.Slc17a6-Gad1Gad2.Asb4_(Periventricular_Fiber_System_(Pv))-|Thalamus / BrainAtlas - Mouse McCarroll V32

DPYS AIPL1 RSPH6A KYNU

4.15e-0594914be1dcfe287f58d608ccdb47cf9c1d12b5e3aa60d
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Slc17a6|Thalamus / BrainAtlas - Mouse McCarroll V32

DPYS AIPL1 RSPH6A KYNU

4.15e-0594914576c37fa53fab679f5e8786f5c798e18998186e9
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

EPHX2 LINS1 FAM184A CAMK4 ASH1L

4.20e-05188915b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A TCAIM TMEM45B CFAP221 GRM1

4.20e-051889152ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 FRZB RXFP1 ABCA9

4.31e-0518991571397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 FRZB RXFP1 ABCA9

4.31e-051899154eea4759520c312bd17a681034d8074e47093d2b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRCAM TENM3 TNC PLXNA4 ST8SIA1

4.31e-05189915e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

DPYS ZFHX4 PLXNA4 PKHD1L1 TNFRSF21

4.31e-0518991587189275234b5d59484c58acbb14a09903f2b578
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 PLD1 ST8SIA1 PKHD1L1 CHST8

4.41e-05190915876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TENM3 MYO7A WFS1 ST8SIA1 PKHD1L1

4.41e-051909159ce301841ce9486701fa28eb2a9929e35d476878
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 PLD1 ST8SIA1 PKHD1L1 CHST8

4.41e-05190915be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 PLD1 ST8SIA1 PKHD1L1 CHST8

4.41e-0519091509a8855901c3c9332dbaab3e40166485b696d0f1
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A ENTPD3 METAP1D CHRFAM7A CHRNA7

4.53e-05191915764c3a8829ae1253a0790744138266e81fc075ec
ToppCellwk_08-11-Epithelial-PNS-SST+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DPYS NRCAM ENTPD3 CHRFAM7A CHST8

4.53e-05191915df2bef74a54f4c23c99bd3b93225fd36bcd90723
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ABCA9

4.64e-051929159093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A ENTPD3 METAP1D CHRFAM7A CHRNA7

4.64e-051929153abee376c37c3646da33ac381aa63d50a01607a6
ToppCellNasal_Brush-Immune-Neutrophils|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

TBXAS1 MYO7A GIMAP2 ASGR1 UNC13D

4.64e-0519291520a7f7beb01df1c4f915ec2f9b5a9dbcab157187
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ABCA9

4.64e-051929159ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRCAM TENM3 TNC PLXNA4 ST8SIA1

4.64e-05192915f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPST1 TENM3 TNC PLXNA4 ST8SIA1

4.64e-05192915df1545670370fb1010c567cd059c2783eab315f7
ToppCelldroplet-Kidney-nan-3m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM3 TNC FRZB ENTPD3 CHST8

4.64e-051929158b625c22dda23c99654c82c529a1233e99e71b54
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE3A ZFHX4 TENM3 TNC TNFRSF21

4.76e-051939157cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 TNC CAMK4 ABCA9

4.76e-05193915f1199518c3626fd29bfce65070dd21a660671213
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 PLXNA4 RXFP1 ABCA9

4.87e-05194915cf0244a29934e515446ac917d3c30672b460fb04
ToppCellIPF-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

DPYS ZFHX4 TENM3 PLXNA4 PKHD1L1

4.87e-05194915d8a26da856a85e3d001d406e992cb18fdd58baef
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A TENM3 TNC PLXNA4 ST8SIA1

4.87e-051949156e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TENM3 PLXNA4 RXFP1 ABCA9

4.87e-05194915ba7f971fb9a19423602da60770f23d9fead4a451
ToppCelldistal-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZFHX4 WFS1 LRRC70 PKHD1L1 CHST8

4.99e-051959158e0f67a67af3bc0b16f48a621f74540f136383b7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TNC CAMK4 ST8SIA1 ABCA9

4.99e-0519591544d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

EPHX2 TPST1 LINS1 CAMK4 ASH1L

4.99e-05195915d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellASK428-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

DPYS ZFHX4 PLXNA4 PKHD1L1 TNFRSF21

4.99e-05195915c750602c765a51075ba6ede78e3ba80b62374481
ToppCelldistal-Endothelial-Lymphatic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZFHX4 WFS1 LRRC70 PKHD1L1 CHST8

5.12e-051969153e8a20e1d163dcbd3bbd99fe179d54af02298af0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TNC CAMK4 ST8SIA1 ABCA9

5.12e-05196915ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A TNC CAMK4 ST8SIA1 ABCA9

5.12e-0519691530ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCelldistal-3-Endothelial-Lymphatic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZFHX4 WFS1 LRRC70 PKHD1L1 CHST8

5.24e-051979159ea0e2ed9c3f97591a06e70570640996580417d5
ToppCellT_cells-Treg_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

EPHX2 FAM184A CAMK4 ST8SIA1 ITGA3

5.24e-05197915de5448fcdf4e433fc167496413abe5d0c8a5c6d8
DrugEucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; HL60; HT_HG-U133A

PTK2B ZFHX4 NRCAM CAMK4 ENTPD3 POU3F1 PLCD1 KYNU

1.15e-061979082556_UP
Diseaseshort-term memory

EPHX2 FAM184A FRZB CHST8

1.04e-0483864EFO_0004335
DiseaseLeber congenital amaurosis (is_implicated_in)

MYO7A AIPL1

1.25e-046862DOID:14791 (is_implicated_in)
Diseasecognitive disorder (implicated_via_orthology)

CHRFAM7A CHRNA7

1.25e-046862DOID:1561 (implicated_via_orthology)
Diseaserheumatoid arthritis (biomarker_via_orthology)

CHRFAM7A CHRNA7

1.25e-046862DOID:7148 (biomarker_via_orthology)
Diseasenicotine dependence (implicated_via_orthology)

CHRFAM7A CHRNA7

5.44e-0412862DOID:0050742 (implicated_via_orthology)
Diseasehypertension (implicated_via_orthology)

TBXAS1 EPHX2 PLCD1 KYNU

5.45e-04128864DOID:10763 (implicated_via_orthology)
Diseaseasthma, body mass index

UNC13D RERE

7.47e-0414862EFO_0004340, MONDO_0004979
Disease5alpha-androstan-3beta,17beta-diol disulfate measurement

TBXAS1 ZNF394

1.87e-0322862EFO_0021115
Diseaseorofacial cleft, sex interaction measurement

NRCAM CHRFAM7A CHRNA7

2.05e-0386863EFO_0008343, MONDO_0000358
Diseasevisuospatial function measurement

FARP1 WRAP73

2.61e-0326862EFO_0803533
Diseaseenergy expenditure

TBXAS1 CFAP77

2.81e-0327862EFO_0005109

Protein segments in the cluster

PeptideGeneStartEntry
WNHSVLHHEEMIGKA

TPST1

261

O60507
TPNWDFHNHEEMKGL

ANKRD20A1

496

Q5TYW2
LPHQWQHKVHFMVSL

ACOT8

241

O14734
VQHHIGPVNTWMGLH

ASGR1

201

P07306
PEMAYGWMVEHKHRH

ASH1L

1471

Q9NR48
QMAQGKDPTEWHVHT

AIPL1

106

Q9NZN9
DWSPMHEAAIHGHQL

ASB9

36

Q96DX5
TLWHMPHFQKVGRHL

CFAP77

271

Q6ZQR2
EDKWPHDMRNHLAGE

CTSL3P

201

Q5NE16
PNAHHLDHKMEIKQW

ATP7B

636

P35670
SWGHRIPMMKEHRDH

ABCA9

141

Q8IUA7
TPNWDFHNHEEMKGL

ANKRD20A4P

496

Q4UJ75
PVTWHHMEDGFHGVL

AADACL3

366

Q5VUY0
LAWKHHMAIEAVHSN

FAM184A

486

Q8NB25
QYHHHDPDGGKMPKW

CHRNA7

316

P36544
QAPKSPWHTHLEMHC

C9orf152

111

Q5JTZ5
NLWHMWVHPHGVETT

ENTPD3

201

O75355
HEWIRNMNVHSLPHG

FBXO21

531

O94952
HLLGNWKAIMAHVPA

ESPNL

806

Q6ZVH7
ESLTQGKEMWDHHTH

LINS1

471

Q8NG48
HPEIWHHANDSDLPM

METAP1D

261

Q6UB28
DWEMHVHFKVHGTGK

LMAN2

111

Q12907
DAMHKPGLWHHQTEV

NRCAM

686

Q92823
QHPWVTGKAANFVHM

CAMK4

296

Q16566
NKEWHHAAHHVMGPP

DPYS

286

Q14117
ESGVKMWHLVKNHEH

PLXNA4

1646

Q9HCM2
MWHLVKNHEHGDQKE

PLXNA4

1651

Q9HCM2
KNDPGHHIIEDMWLG

ITGA3

111

P26006
IPREQLMGHSEWDHK

PDE3A

316

Q14432
KLMHHEWLGAGAGHP

POU3F1

51

Q03052
QYHHHDPDGGKMPKW

CHRFAM7A

226

Q494W8
PHIHHKTTALMMAWH

LRRC70

421

Q7Z2Q7
WVLGLHKIIHHSGSM

PLCD1

121

P51178
HMEDWIPHLKRGHIE

EPHX2

506

P34913
MDQNEHSHWGPHAKG

GIMAP2

1

Q9UG22
IQGMKHLAAHLWKHS

FARP1

631

Q9Y4F1
MVFVPSGWHHQVHNL

JMJD4

306

Q9H9V9
EHHHWIAQMELLPDT

FAM186A

151

A6NE01
HMKSDEIHWLHPQMT

PTK2B

96

Q14289
GQHMWHRLSVHVKTN

GRM1

906

Q13255
MDQVHHMQHSKWQHP

S100PBP

351

Q96BU1
WVNHGRGMVKEHNNH

FAM171B

301

Q6P995
KVLYPHHMAQVHWSG

CDH16

251

O75309
QFLHHTDIIPGIMHW

CFAP221

706

Q4G0U5
NPWNKEMGDHLVKHG

HPD

76

P32754
DSMANWVHHTQHILP

RSPH6A

536

Q9H0K4
LLEWTHHSMKPHEIP

SENP2

526

Q9HC62
WEHVLHLMNHMNLLP

UTP25

491

Q68CQ4
HVMLGTMDVHHHWTK

TCAIM

281

Q8N3R3
HKHFDINEHLPWMIV

TNFRSF21

341

O75509
MPWHDIASAVHGKAA

PLD1

676

Q13393
WPFSVNMHEQPISHH

ST8SIA1

296

Q92185
WSGAPMIDNSHHTHL

NOM1

616

Q5C9Z4
NHVTWKMITEFGHPA

WRAP73

251

Q9P2S5
AMEQQWLHGHPHMHG

RERE

1531

Q9P2R6
HFHRMEKAHPEPGTW

SULT1A4

141

P0DMN0
HFHRMEKAHPEPGTW

SULT1A3

141

P0DMM9
WQHVPIIAMETHGAH

SDSL

191

Q96GA7
HWIIHGRPEKDMHGY

SARDH

426

Q9UL12
GVMEVLKKHHKPHWN

STAT5A

576

P42229
HMPGHVEALKLWSLN

CILP2

671

Q8IUL8
LDVHRPVGMDIHWDH

CHST8

316

Q9H2A9
SQGWVHYMIHEPEPH

CKS1B

51

P61024
SLGWVHYMIHEPEPH

CKS2

51

P33552
PHLHLYHENHWIKLM

TMEM45B

71

Q96B21
LEMAVGALHHDPEHW

TBXAS1

431

P24557
AFPTLELWQEHQHMH

ZFHX4

2456

Q86UP3
FHMVTWHVLKPHKSD

ZNF394

321

Q53GI3
HSNPVHWQHMETIEL

MPDZ

246

O75970
HGDWVHIFPEGKVNM

TAFAZZIN

141

Q16635
PQDKHWLAEQHHMRA

DNTTIP1

246

Q9H147
LPWNMTKMPNHLHHS

FRZB

46

Q92765
KWMNVDHPIHLGDEQ

RNF10

311

Q8N5U6
HWKGHEHSIQFAEMK

TNC

2171

P24821
HQRIHMEEKPHQWSA

ZNF322

311

Q6U7Q0
MPRLHWLDLEGNHIH

RXFP1

246

Q9HBX9
MGGWTLDKHHVLDVQ

TENM3

1111

Q9P273
HTWERMWMHVAKVHP

VASH2

61

Q86V25
PHKIHWIEKANHSMA

TEX30

181

Q5JUR7
HTPNKAGFRWEHEMV

PKHD1L1

2781

Q86WI1
SPNDLQKHFQMWHHG

ZNF518A

131

Q6AHZ1
QKHFQMWHHGELPSY

ZNF518A

136

Q6AHZ1
KEMVANWRHHPAVVE

RALGAPB

221

Q86X10
VPHDWRKMAEAVQNH

TXNRD2

121

Q9NNW7
WIPSFGKNHRVHMAE

ZNF548

136

Q8NEK5
HKMVTALGTHWHPEH

TGFB1I1

296

O43294
HFDMHRVGKWHQDFP

ZNF75A

116

Q96N20
SHGGHLQHIMKWLEG

WDR24

761

Q96S15
TTEWFHLKQQHHQPM

UNC13D

466

Q70J99
AQHMSPWDEKHVLRG

ULK3

161

Q6PHR2
GMHWLSTIIPTHHIN

WFS1

311

O76024
HEKHAHTIKPALVGW

KYNU

291

Q16719
HWISPQNATHIKPMH

MYO7A

46

Q13402