Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionMHC class Ib protein binding

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

7.27e-0816524GO:0023029
GeneOntologyMolecularFunctionMHC class Ib receptor activity

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

1.54e-0719524GO:0032394
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

HTR3E CHRNA2 CHRNA4 CHRNB1

4.68e-0643524GO:0005231
GeneOntologyMolecularFunctionmethionine adenosyltransferase activity

MAT1A MAT2A

6.65e-062522GO:0004478
GeneOntologyMolecularFunctionacetylcholine-gated monoatomic cation-selective channel activity

CHRNA2 CHRNA4 CHRNB1

1.10e-0517523GO:0022848
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

HTR3E CHRNA2 CHRNA4 CHRNB1

1.46e-0557524GO:1904315
GeneOntologyMolecularFunctionMHC protein binding

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

1.56e-0558524GO:0042287
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

HTR3E CHRNA2 CHRNA4 CHRNB1

1.79e-0560524GO:0099529
GeneOntologyMolecularFunctiontransmitter-gated channel activity

HTR3E CHRNA2 CHRNA4 CHRNB1

2.46e-0565524GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

HTR3E CHRNA2 CHRNA4 CHRNB1

2.46e-0565524GO:0022824
GeneOntologyMolecularFunctionacetylcholine receptor activity

CHRNA2 CHRNA4 CHRNB1

2.84e-0523523GO:0015464
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

3.14e-05140525GO:0099094
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR51A4 TGFBR3 MET IL12RB2 HTR3E KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1 CHRNA2 CHRNA4 CHRNB1 OR51H1

3.15e-0513535213GO:0004888
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

HTR3E CHRNA2 CHRNA4 CHRNB1

4.33e-0575524GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

HTR3E CHRNA2 CHRNA4 CHRNB1

4.81e-0577524GO:0005230
GeneOntologyMolecularFunctionimmune receptor activity

IL12RB2 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

6.88e-05165525GO:0140375
GeneOntologyMolecularFunctionneurotransmitter receptor activity

HTR3E CHRNA2 CHRNA4 CHRNB1

1.33e-04100524GO:0030594
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

1.44e-04193525GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

1.58e-04197525GO:0022834
GeneOntologyMolecularFunctiongated channel activity

CLCN6 HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

2.23e-04334526GO:0022836
GeneOntologyMolecularFunctionacetylcholine binding

CHRNA4 CHRNB1

5.09e-0413522GO:0042166
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CLCN6 HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

1.19e-03459526GO:0005216
GeneOntologyMolecularFunctionmonoatomic cation channel activity

HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

1.95e-03343525GO:0005261
GeneOntologyMolecularFunctionchannel activity

CLCN6 HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

2.34e-03525526GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CLCN6 HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

2.37e-03526526GO:0022803
GeneOntologyMolecularFunctionGTPase activator activity

AGAP7P BCR AGAP4 AGAP6

5.97e-03279524GO:0005096
GeneOntologyMolecularFunctionquaternary ammonium group binding

CHRNA2 CHRNA4

6.40e-0346522GO:0050997
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

MET SYNE1 HTR3E CHRNA2 CHRNA4 CHRNB1

1.01e-06130536GO:0060079
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

MET SYNE1 HTR3E CHRNA2 CHRNA4 CHRNB1

2.06e-06147536GO:0099565
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

MET SYNE1 HTR3E CHRNA2 CHRNA4 CHRNB1

6.64e-06180536GO:0060078
GeneOntologyBiologicalProcessresponse to nicotine

KCNK1 CHRNA2 CHRNA4 CHRNB1

1.49e-0558534GO:0035094
GeneOntologyBiologicalProcessS-adenosylmethionine biosynthetic process

MAT1A MAT2A

3.87e-054532GO:0006556
GeneOntologyBiologicalProcessnegative regulation of apoptotic process involved in morphogenesis

TGFBR3 BMP7

1.35e-047532GO:1902338
GeneOntologyBiologicalProcessactivation of GTPase activity

AGAP7P BCR AGAP4 AGAP6

1.77e-04109534GO:0090630
GeneOntologyBiologicalProcessnegative regulation of apoptotic process involved in development

TGFBR3 BMP7

1.80e-048532GO:1904746
GeneOntologyBiologicalProcesssynaptic transmission, cholinergic

CHRNA2 CHRNA4 CHRNB1

1.97e-0444533GO:0007271
GeneOntologyBiologicalProcessamino acid metabolic process

ASNSD1 MAT1A ALDH18A1 AASDH AADAT GGT5

2.02e-04332536GO:0006520
GeneOntologyBiologicalProcessregulation of GTPase activity

MET AGAP7P BCR AGAP4 AGAP6 RASGRP2

2.12e-04335536GO:0043087
GeneOntologyBiologicalProcessaspartate family amino acid metabolic process

ASNSD1 MAT1A AADAT

2.55e-0448533GO:0009066
GeneOntologyBiologicalProcessacetylcholine receptor signaling pathway

CHRNA2 CHRNA4 CHRNB1

3.06e-0451533GO:0095500
GeneOntologyBiologicalProcesscellular response to acetylcholine

CHRNA2 CHRNA4 CHRNB1

3.43e-0453533GO:1905145
GeneOntologyBiologicalProcessbehavioral response to nicotine

CHRNA4 CHRNB1

3.51e-0411532GO:0035095
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

AGAP7P BCR AGAP4 AGAP6 RASGRP2

4.02e-04244535GO:0043547
GeneOntologyBiologicalProcessresponse to acetylcholine

CHRNA2 CHRNA4 CHRNB1

4.03e-0456533GO:1905144
GeneOntologyBiologicalProcessnegative regulation of mesenchymal cell apoptotic process

BMP7 SYNE1

4.96e-0413532GO:2001054
GeneOntologyBiologicalProcessregulation of membrane potential

MET SYNE1 HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

5.41e-04559537GO:0042391
GeneOntologyBiologicalProcessregulation of dendrite development

MET BMP7 SYNE1 FAT3

5.97e-04150534GO:0050773
GeneOntologyBiologicalProcessregulation of apoptotic process involved in morphogenesis

TGFBR3 BMP7

6.66e-0415532GO:1902337
GeneOntologyBiologicalProcessaspartate family amino acid catabolic process

MAT1A AADAT

6.66e-0415532GO:0009068
GeneOntologyCellularComponentacetylcholine-gated channel complex

CHRNA2 CHRNA4 CHRNB1

1.22e-0518533GO:0005892
GeneOntologyCellularComponentmethionine adenosyltransferase complex

MAT1A MAT2A

1.89e-053532GO:0048269
GeneOntologyCellularComponentpostsynaptic membrane

MET SYNE1 HTR3E CHRNA2 CHRNA4 CHRNB1

5.42e-04405536GO:0045211
GeneOntologyCellularComponentreceptor complex

TGFBR3 MET IL12RB2 HTR3E CHRNA2 CHRNA4 CHRNB1

6.29e-04581537GO:0043235
GeneOntologyCellularComponentsynaptic membrane

MET SYNE1 HTR3E KCNK1 CHRNA2 CHRNA4 CHRNB1

6.41e-04583537GO:0097060
MousePhenofused cornea and lens

AGAP7P AGAP4 AGAP6

4.89e-0524423MP:0001307
MousePhenoabnormal lens development

BMP7 AGAP7P AGAP4 AGAP6

8.55e-0578424MP:0005545
Domain-

HTR3E CHRNA2 CHRNA4 CHRNB1

4.55e-07235241.20.120.370
DomainAcetylcholine_rcpt_TM

HTR3E CHRNA2 CHRNA4 CHRNB1

4.55e-0723524IPR027361
DomainNeurotransmitter_ion_chnl_CS

HTR3E CHRNA2 CHRNA4 CHRNB1

7.31e-0645524IPR018000
DomainS-AdoMet_synt_M

MAT1A MAT2A

7.60e-062522PF02772
DomainS-AdoMet_synt_C

MAT1A MAT2A

7.60e-062522PF02773
DomainADOMET_SYNTHASE_CS

MAT1A MAT2A

7.60e-062522IPR022631
DomainS-AdoMet_synt_C

MAT1A MAT2A

7.60e-062522IPR022630
DomainS-AdoMet_synthetase_sfam

MAT1A MAT2A

7.60e-062522IPR022636
DomainS-AdoMet_synt_N

MAT1A MAT2A

7.60e-062522PF00438
DomainS-AdoMet_synt_central

MAT1A MAT2A

7.60e-062522IPR022629
DomainS-AdoMet_synt_N

MAT1A MAT2A

7.60e-062522IPR022628
DomainS-AdoMet_synthetase

MAT1A MAT2A

7.60e-062522IPR002133
DomainADOMET_SYNTHASE_1

MAT1A MAT2A

7.60e-062522PS00376
DomainADOMET_SYNTHASE_2

MAT1A MAT2A

7.60e-062522PS00377
DomainNeur_chan_memb

HTR3E CHRNA2 CHRNA4 CHRNB1

7.99e-0646524PF02932
DomainNeur_chan_LBD

HTR3E CHRNA2 CHRNA4 CHRNB1

8.72e-0647524PF02931
DomainNEUROTR_ION_CHANNEL

HTR3E CHRNA2 CHRNA4 CHRNB1

8.72e-0647524PS00236
DomainNeurotrans-gated_channel_TM

HTR3E CHRNA2 CHRNA4 CHRNB1

8.72e-0647524IPR006029
Domain-

HTR3E CHRNA2 CHRNA4 CHRNB1

8.72e-06475242.70.170.10
DomainNeur_channel

HTR3E CHRNA2 CHRNA4 CHRNB1

8.72e-0647524IPR006201
DomainNeur_chan_lig-bd

HTR3E CHRNA2 CHRNA4 CHRNB1

8.72e-0647524IPR006202
DomainNicotinic_acetylcholine_rcpt

CHRNA2 CHRNA4 CHRNB1

1.11e-0516523IPR002394
DomainArfGap

AGAP7P AGAP4 AGAP6

7.07e-0529523SM00105
DomainArfGap

AGAP7P AGAP4 AGAP6

7.07e-0529523PF01412
DomainARFGAP

AGAP7P AGAP4 AGAP6

7.07e-0529523PS50115
DomainArfGAP

AGAP7P AGAP4 AGAP6

7.07e-0529523IPR001164
Domainig

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.82e-04190525PF00047
DomainImmunoglobulin

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.82e-04190525IPR013151
DomainIg-like_fold

MET IL12RB2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

3.26e-03706527IPR013783
DomainNtn_hydrolases_N

ASNSD1 GGT5

3.80e-0333522IPR029055
DomainLAM_G_DOMAIN

FAT1 FAT3

5.01e-0338522PS50025
DomainLaminin_G_2

FAT1 FAT3

5.54e-0340522PF02210
DomainIG

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

6.19e-03421525SM00409
DomainIg_sub

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

6.19e-03421525IPR003599
DomainLamG

FAT1 FAT3

6.67e-0344522SM00282
DomainPH

AGAP7P BCR AGAP4 AGAP6

7.43e-03278524SM00233
DomainPH_DOMAIN

AGAP7P BCR AGAP4 AGAP6

7.52e-03279524PS50003
DomainPH_domain

AGAP7P BCR AGAP4 AGAP6

7.61e-03280524IPR001849
Domain-

MET IL12RB2 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

9.95e-036635262.60.40.10
DomainLaminin_G

FAT1 FAT3

1.14e-0258522IPR001791
PathwayKEGG_ANTIGEN_PROCESSING_AND_PRESENTATION

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

7.58e-0688445M16004
PathwayKEGG_GRAFT_VERSUS_HOST_DISEASE

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

7.68e-0641444M13519
PathwayREACTOME_DAP12_INTERACTIONS

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

2.33e-0554444MM14871
PathwayKEGG_SELENOAMINO_ACID_METABOLISM

MAT1A MAT2A GGT5

7.02e-0526443M7151
PathwayWP_METHYLATION_PATHWAYS

MAT1A MAT2A

3.38e-049442M39493
PathwayREACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA2 CHRNA4

3.38e-049442M27597
PathwayREACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA2 CHRNA4

3.38e-049442MM15313
PathwayWP_METHYLATION

MAT1A MAT2A

3.38e-049442MM15836
PathwayKEGG_MEDICUS_REFERENCE_METHIONINE_DEGRADATION

MAT1A MAT2A

4.22e-0410442M47939
PathwayREACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA2 CHRNA4

5.14e-0411442M883
PathwayREACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA2 CHRNA4

6.16e-0412442M48008
PathwayREACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA2 CHRNA4

6.16e-0412442MM15312
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

8.11e-04135444MM14781
PathwayREACTOME_METHYLATION

MAT1A MAT2A

8.46e-0414442MM14596
PathwayREACTOME_METHYLATION

MAT1A MAT2A

8.46e-0414442M26967
PathwayREACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS

CHRNA2 CHRNA4

8.46e-0414442M757
PathwayKEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

8.57e-04137444M5669
PathwayREACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS

CHRNA2 CHRNA4

9.74e-0415442MM14704
Pubmed

A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

3.78e-13853515730517
Pubmed

[Distribution of immunoglobulin like receptor gene in Han population in China and the impact thereof on the HLA-identical sibling hematopoietic stem cell transplantation].

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.80e-12453418269867
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.34e-111453519875891
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.34e-111453515896204
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.34e-111453519489269
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.01e-111553520082646
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.01e-111553519926642
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.01e-111553520356536
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.01e-111553520643584
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.01e-111553517498266
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.01e-111553519326408
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653519897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653519000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653520670355
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653519527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653520652381
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653518668235
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653519279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653517868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653518643961
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653519309280
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653520331834
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653516403292
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.92e-111653520210919
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753519032228
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753520173792
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753520483367
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753519968064
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753519218127
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753519169284
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753520878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753520650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753519450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.13e-111753519761533
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

5.71e-111853519630074
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

5.71e-111853520519398
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

5.71e-111853520200544
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

5.71e-111853519046302
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

5.71e-111853519846535
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

5.71e-111853520580654
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

5.71e-111853520210918
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

7.75e-111953518571006
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

7.75e-111953518778326
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

7.75e-111953520600442
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of ParanĂ¡.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

7.75e-111953518848853
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.03e-102053520193031
Pubmed

Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.35e-102153519861144
Pubmed

Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

1.68e-10753412618911
Pubmed

Expression of a killer cell receptor-like gene in plastic regions of the central nervous system.

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

1.68e-10753415748957
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.75e-102253520492596
Pubmed

Genotypes of NK cell KIR receptors, their ligands, and Fcγ receptors in the response of neuroblastoma patients to Hu14.18-IL2 immunotherapy.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

3.35e-10853420935224
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

6.02e-1095347749980
Pubmed

Immunogenetic characteristics of patients with autoimmune gastritis.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

7.82e-102953520082482
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.00e-091053412559621
Pubmed

Natural killer cells and immune surveillance.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.57e-091153418830515
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.57e-091153419664392
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.12e-093553519683555
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.36e-091253420371502
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.36e-091253419181658
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

2.36e-091253417490516
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.36e-091253419936734
Pubmed

Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC.

KIR2DL1 KIR2DL3 KIR3DL1

3.34e-09353330698860
Pubmed

Comparison of killer Ig-like receptor genotyping and phenotyping for selection of allogeneic blood stem cell donors.

KIR2DL1 KIR2DL2 KIR2DL3

3.34e-09353315879158
Pubmed

[Effect of demethylation treatment on the expression of inhibitory receptor KIR gene in NK-92MI cell line].

KIR2DL1 KIR2DL2 KIR2DL3

3.34e-09353319549382
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

3.40e-091353418687225
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

3.40e-091353419934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

3.40e-091353419120281
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.76e-091453419421224
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR3DL3 KIR2DL1 KIR2DL2 KIR3DL1

4.76e-091453418945962
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

6.48e-091553419850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

6.48e-091553420207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

6.48e-091553419493232
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3

1.13e-081753420173784
Pubmed

B-lymphoma cells escape rituximab-triggered elimination by NK cells through increased HLA class I expression.

KIR2DL1 KIR2DL2 KIR2DL3

1.34e-08453320056126
Pubmed

HLA-C and KIR genes in hepatitis C virus infection.

KIR2DL1 KIR2DL2 KIR2DL3

1.34e-08453316571411
Pubmed

Genetic interactions of KIR and G1M immunoglobulin allotypes differ in obese from non-obese individuals with type 2 diabetes.

KIR2DL1 KIR2DL3 KIR3DL1

1.34e-08453318632158
Pubmed

High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR.

KIR2DL2 KIR2DL3 KIR3DL1

1.34e-08453319522772
Pubmed

[Analysis of HLA-Cw, KIR2D genetic variations in 2 Chinese populations].

KIR2DL1 KIR2DL2 KIR2DL3

1.34e-08453318543232
Pubmed

NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts.

KIR2DL1 KIR2DL3 KIR3DL1

1.34e-08453327732638
Pubmed

Oligoclonal band phenotypes in MS differ in their HLA class II association, while specific KIR ligands at HLA class I show association to MS in general.

KIR2DL1 KIR2DL2 KIR2DL3

1.34e-08453325037176
Pubmed

Investigation of activating and inhibitory killer cell immunoglobulin-like receptors and their putative ligands in type 1 diabetes (T1D).

KIR2DL1 KIR2DL2 KIR2DL3

1.34e-08453326542066
Pubmed

Study of the KIR gene profiles and analysis of the phylogenetic relationships of Rajbanshi population of West Bengal, India.

KIR2DL1 KIR2DL3 KIR3DL1

1.34e-08453323354323
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR3DL3 KIR2DL1 KIR2DL2 KIR3DL1

2.29e-082053420426625
Pubmed

Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis.

KIR2DL1 KIR2DL2 KIR2DL3

3.33e-08553316112031
Pubmed

Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

KIR2DL1 KIR2DL3 KIR3DL1

3.33e-0855337716543
Pubmed

Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters.

KIR2DL1 KIR2DL2 KIR2DL3

3.33e-08553312121272
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus.

KIR2DL1 KIR2DL2 KIR2DL3

3.33e-08553318755860
Pubmed

Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3.

KIR2DL1 KIR2DL2 KIR2DL3

3.33e-08553318322206
Pubmed

KIR 2D (L1, L3, L4, S4) and KIR 3DL1 protein expression in non-small cell lung cancer.

KIR2DL1 KIR2DL3 KIR3DL1

3.33e-08553327893413
Pubmed

Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.

KIR2DL1 KIR2DL2 KIR3DL1

1.16e-07753314607943
Pubmed

Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.

KIR2DL1 KIR2DL3 KIR3DL1

1.16e-07753326928464
Pubmed

Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors.

KIR2DL1 KIR2DL2 KIR2DL3

1.16e-07753311169255
Pubmed

Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.

KIR2DL1 KIR2DL3 KIR3DL1

1.16e-0775339430220
Pubmed

KIR haplotype content at the allele level in 77 Northern Irish families.

KIR2DL2 KIR2DL3 KIR3DL1

1.86e-07853317200871
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR2DL1 KIR2DL3 KIR3DL1

1.86e-0785339430221
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DL1 KIR2DL2 KIR2DL3

1.86e-07853318681957
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP7P AGAP4 AGAP6

2.79e-07953312640130
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR2DL2 KIR2DL3 KIR3DL1

2.79e-0795338662091
Pubmed

Distribution of KIR genes in the Czech population.

KIR3DL3 KIR2DL1 KIR3DL1

2.79e-07953318186800
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP7P AGAP4 AGAP6

3.98e-071053320664521
InteractionKIR3DL1 interactions

KIR2DL1 KIR2DL2 KIR3DL1

4.55e-0613523int:KIR3DL1
InteractionKIR2DL2 interactions

KIR2DL1 KIR2DL2 KIR3DL1

4.55e-0613523int:KIR2DL2
InteractionKIR2DL1 interactions

KIR2DL1 KIR2DL2 KIR3DL1

5.07e-0528523int:KIR2DL1
Cytoband19q13.4

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.23e-067953419q13.4
Cytoband10q11.23

AGAP7P AGAP6

6.75e-043353210q11.23
CytobandEnsembl 112 genes in cytogenetic band chr10q11

AGAP7P AGAP4 AGAP6

1.36e-03188533chr10q11
Cytoband22q11.23

BCR GGT5

1.74e-035353222q11.23
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

5.65e-1018445620
GeneFamilyCholinergic receptors nicotinic subunits

CHRNA2 CHRNA4 CHRNB1

7.37e-0616443173
GeneFamilyArfGAPs

AGAP7P AGAP4 AGAP6

6.97e-0533443395
GeneFamilyCadherin related

FAT1 FAT3

7.69e-041744224
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP4 AGAP6

7.69e-04174421291
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AGAP7P BCR AGAP4 AGAP6

1.56e-03206444682
GeneFamilyADAM metallopeptidase domain containing|CD molecules

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

2.59e-03394445471
GeneFamilyOlfactory receptors, family 51

OR51A4 OR51H1

5.13e-0344442164
CoexpressionKAZMIN_PBMC_P_FALCIPARUM_RTSS_AS01_AGE_UNKNOWN_CORRELATED_WITH_PROTECTION_56DY_NEGATIVE

TGFBR3 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

6.68e-1049536M40909
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

NKD2 AGAP7P AGAP4 AGAP6

9.36e-0737534MM1121
CoexpressionHOFT_PBMC_TICE_BCG_RBCG_AG85A_AG85B_AGE_18_40YO_CORRELATED_WITH_WHOLE_BLOOD_BACTERICIDAL_ACTIVITY_NEGATIVE

TGFBR3 IL12RB2 SYNE1 KIR3DL1

1.29e-0640534M41034
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CD16_POS_NK_CELL

KIR2DL1 KIR2DL3 KIR3DL1

6.23e-0618533M45763
CoexpressionGSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN

KIR3DL3 KIR2DL2 KIR2DL3 KIR3DL1 CHRNB1

4.11e-05190535M4662
CoexpressionGSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN

TGFBR3 CLCN6 KIR2DL1 KIR2DL2 KIR2DL3

5.12e-05199535M9885
CoexpressionKARLSSON_TGFB1_TARGETS_DN

MET AGAP7P AGAP4 TLCD3A AGAP6

6.46e-05209535MM1058
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN

AGAP7P AGAP4 AGAP6

9.75e-0544533MM485
ToppCellCOVID-19-T_cells-NK_cells|COVID-19 / group, cell type (main and fine annotations)

TGFBR3 IL12RB2 KLF12 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

2.70e-09189537b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCell10x5'-blood-Lymphocytic_NK|blood / Manually curated celltypes from each tissue

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1 BCR

3.36e-09195537c1db871e8e8e8b8d6a5798bc43eaf54e102b75eb
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TGFBR3 SYNE1 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

5.46e-08171536adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1 BCR

5.66e-08172536701de463f85aaad3a4b36a0d5fbc416406620089
ToppCellwk_15-18-Hematologic_Lymphocytic-NK-Activated_NK|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TGFBR3 IL12RB2 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

6.48e-081765366802ed40eb0f91674d4f0120a3d4888c8a2e9612
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-mature_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

6.71e-081775360f2616a81f8fbede77c860b2126e3fa826672da3
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

7.41e-081805361c8398342d3fa4d5ca9a8a63626cc497c5291446
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

7.41e-08180536ddbab26b05f057bd78b78773381cd447bd2e2726
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK-T_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

7.41e-081805360a98d21fec67a890e75ebf0e2d23adddd77da214
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

8.99e-08186536165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCellCOPD-Lymphoid-NK|World / Disease state, Lineage and Cell class

TGFBR3 IL12RB2 KLF12 SYNE1 KIR3DL1 BCR

9.89e-08189536c0ac160fa7e68b92414fb1600abcac8ad1a42232
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-mature_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

1.09e-07192536e48bbcb97c113f323ad4db96bd10d593b9206923
ToppCellImmune-natural_killer_cell|World / Lineage, Cell type, age group and donor

TGFBR3 IL12RB2 KLF12 KIR2DL1 KIR2DL3 KIR3DL1

1.09e-0719253668121a6ef4115a93d87aad8802ef9b27d793d8c0
ToppCellLeuk-UTI-Lymphocyte-T_NK-NK|Leuk-UTI / Disease, Lineage and Cell Type

TGFBR3 SYNE1 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

1.15e-0719453636afc4e48d267be3b8aa1e33fad043bcd54c6bc5
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD16|blood / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1 BCR

1.15e-07194536c34a32f1cfe3e597cb0f91ba5bdd3e114e9f3d2e
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.15e-07194536ae5357e2a276473cde1fc8c43acaf9f69da35fd7
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.15e-071945363a0b8b5d0354c43da57bb951cd8ba878363c3de5
ToppCell10x5'-Lung-Lymphocytic_NK|Lung / Manually curated celltypes from each tissue

TGFBR3 KLF12 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.19e-07195536a5a10ef9254c266316e5591bec19e159cc3caead
ToppCellInfluenza_Severe-NK|Influenza_Severe / Disease group and Cell class

TGFBR3 KLF12 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.26e-07197536d0f58ee4c02573d214deb210bb7efd3d6118f267
ToppCellSevere_COVID-19-T/NK-NK|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.26e-07197536cc20162892b59e48653981f91fc9a0c27064444d
ToppCellSevere-Lymphoid-NK-NK|Severe / Condition, Lineage, Cell class and cell subclass

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.26e-07197536d5b94f9f73e9d050245841b19b046242a32c6258
ToppCellSevere-Lymphoid-NK|Severe / Condition, Lineage, Cell class and cell subclass

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.30e-0719853626b6d20527d22ce68067cdaea6b4330cb779f91b
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TGFBR3 IL12RB2 SYNE1 KIR2DL2 KIR2DL3 KIR3DL1

1.34e-07199536df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL2 KIR3DL1

1.34e-07199536e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellCOVID-19_Moderate-NK|World / disease group, cell group and cell class

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.34e-07199536c41b67b760831c7d5e19fabcc932a056dc560f93
ToppCellCOVID-19_Moderate-NK|COVID-19_Moderate / disease group, cell group and cell class

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.34e-07199536e0e83ba511957be9ad3413460dcb6b7d7b65dd18
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL2 KIR3DL1

1.34e-071995365f914962e2572b0c6372465b81b7496fa663d93c
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1 RASGRP2

1.34e-0719953600ef3cc5c02639bfb839075ecf5f20026ff81f84
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TGFBR3 IL12RB2 SYNE1 KIR2DL2 KIR2DL3 KIR3DL1

1.34e-07199536ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-NK|Influenza_Severe / Disease, condition lineage and cell class

TGFBR3 KLF12 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.38e-0720053604ac14414d550b14dc46d682e7af9dd43982211a
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TGFBR3 IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

1.38e-072005360a6fc7eff94e2f71af9f31a01779aafd2f4a6699
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMAA IL12RB2 CTC1 ALDH18A1 ACOX3

5.36e-071335352ec3490cbf60152c3cece95eb566d749c9666517
ToppCell368C-Lymphocytic-NK_cells|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZGRF1 KCNK1 KIR2DL1 KIR2DL3 KIR3DL1

9.72e-0715053517b3ac5ddc47b9cba0a27b268d63a6e491b2b111
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|GI_small-bowel / Manually curated celltypes from each tissue

MET KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

1.14e-061555351c67f58ed79331addbc012dab0cb09a7f350aedb
ToppCellCOVID-19-kidney-NK|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL12RB2 KLF12 KIR2DL1 KIR2DL3 KIR3DL1

2.45e-061815358906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-mature_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

2.58e-061835358746e6ecc6bf9e194cc9cdf9b07da63f0fcf8b5f
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MET BMP7 FAT1 KCNK1 ALDH18A1

2.58e-06183535bbf27d2f4369031fadacacd6c432c06b1ec5abdb
ToppCellControl-T_cells-NK_cells|Control / group, cell type (main and fine annotations)

TGFBR3 KLF12 KIR2DL1 KIR2DL3 KIR3DL1

2.72e-06185535755c0998c729f462399f1d5e88adf4bfae31be30
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

2.80e-06186535facc1bd8920003ad03d1893c32fc606d82b4d50a
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD8+_T_activated|COVID-19_Severe / Disease group, lineage and cell class

TGFBR3 SYNE1 KIR2DL1 KIR3DL1 DDX24

2.87e-061875354c4c4406e16a15dedcd50bbcc2059d722a2e3d2c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 TGFBR3 KLF12 SYNE1 FAT3

2.95e-061885353177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellCOPD-Lymphoid-NK|COPD / Disease state, Lineage and Cell class

TGFBR3 KLF12 SYNE1 KIR3DL1 BCR

2.95e-06188535c9a227c8e71b69929d43e9afb8306a95c8163778
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-CD56_bright_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

2.95e-061885350a2be6eac6fde669fbc58fd1b2e93e4acf17ddde
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

3.02e-06189535723c57f278919e8251d56b3d19411f9088319450
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

3.02e-06189535960374f5fb278659500a7c948c3068a95dd62eb0
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TGFBR3 SYNE1 KIR2DL1 KIR3DL1 DDX24

3.10e-06190535b9182c84e44aa31684b5388cf3ef4fd1b9e51de4
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.10e-061905351f890be1ac8613a098b271945f25a58c3c2530ab
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TGFBR3 SYNE1 KIR2DL1 KIR3DL1 DDX24

3.10e-0619053588c092a5e78ccaddf406f8fff74376bb761b9790
ToppCellwk_08-11-Hematologic_Lymphocytic-NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1 RASGRP2

3.10e-0619053586b0d142b7d1a3b35580edd104f947106be2c9c6
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TGFBR3 SYNE1 KIR2DL1 KIR3DL1 DDX24

3.10e-061905354b42a16902d7d1494f953cc88af1e761e76bdf2c
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.10e-06190535d7cecf88451f736f8f3f6f4644504cf22846cd6e
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TGFBR3 SYNE1 KIR2DL1 KIR3DL1 DDX24

3.10e-061905359501f0995f3d52be90c02b1aa0c7d184bd788c16
ToppCellControl-Lymphoid-NK|Control / Disease state, Lineage and Cell class

TGFBR3 IL12RB2 KLF12 SYNE1 KIR3DL1

3.10e-06190535f7bd8521a40ac30a64dc439f17e2f6c7d021ef65
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|lymph-node_spleen / Manually curated celltypes from each tissue

IL12RB2 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

3.18e-06191535f802a4686ecf00e8302047bfe23356f24b266cf8
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TGFBR3 KLF12 KIR2DL1 KIR2DL3 KIR3DL1

3.18e-061915359b8b64a36e27a2523b8730c7922fd7ad865a021e
ToppCell10x5'v1-week_17-19-Lymphocytic_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1

3.26e-0619253563e815664b228575886396387d2738cd73855759
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo|lymph-node_spleen / Manually curated celltypes from each tissue

IL12RB2 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

3.26e-061925354d72b9264ed62e0c08cde4078061b348253f6989
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1

3.26e-06192535095151a4f878944835945f698aa0e3b540ffc8c3
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK|lymph-node_spleen / Manually curated celltypes from each tissue

IL12RB2 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.35e-06193535e325cf49e159c6be205ed93adaa09efdd0c122b4
ToppCell3'_v3-Lung-Lymphocytic_NK|Lung / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.35e-06193535a98ee519e0da93ae4a2dcdda1ee8b4138dec131b
ToppCellCOVID-19_Severe-CD8+_T_activated|World / disease group, cell group and cell class

TGFBR3 SYNE1 KIR2DL1 KIR3DL1 DDX24

3.35e-06193535ddc1db516568e03be8e82b2ca770c67756418185
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-CD56_bright_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1

3.35e-0619353546f94a1062b098205e8ce3ed380c0202a4d97678
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TGFBR3 IL12RB2 KLF12 KIR2DL1 KIR3DL1

3.35e-061935351cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell10x5'v1-week_14-16-Lymphocytic_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1

3.43e-061945355a859885c0f9b8554b0d203e371c70928ad4418f
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1

3.43e-061945357d35ac70ba966eb1fee4197f7de6d6116326a442
ToppCellICU-NoSEP-Lymphocyte-T_NK-NK|ICU-NoSEP / Disease, Lineage and Cell Type

TGFBR3 SYNE1 KIR3DL3 KIR2DL1 KIR2DL3

3.43e-06194535090edfc884655e5ab38b027c6e1a5aa809ebb19d
ToppCell10x5'v1-week_12-13-Lymphocytic_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1

3.43e-061945355afe7f48d3383f3dac18765f97999c8b6936dc1b
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFBR3 IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1

3.43e-06194535ec7e0ca6c9a2f63938e06ee771da09eff14fc3b5
ToppCellT_cells-CD56_dim_CD16+_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TGFBR3 SYNE1 KIR2DL2 KIR2DL3 KIR3DL1

3.43e-06194535335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCell3'_v3-Lung-Lymphocytic_NK-NK_CD16|Lung / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.43e-061945353337042eef91a49f621058785723228cf4dfdad4
ToppCellIIF-Lymphocyte-T_NK-NK|IIF / Disease, Lineage and Cell Type

TGFBR3 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

3.52e-06195535464ce05cb52f78aee22d3baa6641b37bd53aae16
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.52e-0619553598b02beafe1d418442e41f85cbf0c7b194fe5957
ToppCellCOVID-19-lung-NK/NKT|lung / Disease (COVID-19 only), tissue and cell type

TGFBR3 IL12RB2 KLF12 KIR2DL3 KIR3DL1

3.52e-061955353ab941a369e3815f338890b116dc77aefa054098
ToppCell10x5'-Lung-Lymphocytic_NK-NK_CD16|Lung / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.52e-06195535e91e7f89163c615b706f3297b641b1e4c966f5e6
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD16|lymph-node_spleen / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.52e-06195535e756733cf48768bf40058d6cf9039e52f7563133
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.52e-061955359ecae6c26a0d0607d101ccf1c38f0b23c5a256a8
ToppCellCOVID-19-Lymphoid-CD8_T_cells|Lymphoid / Condition, Lineage and Cell class

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.52e-06195535d4c70a462b98963e78f4e2659574bc350f8ffe1a
ToppCellT/NK_cells-CD56dim_NK_cell|World / Lineage and Cell class

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.52e-061955356124e87cb9061bf8918377fb4a79084079ddfc16
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.52e-061955350b50b5c71a4949f3f8fb9f5c30f9d50f53ca050d
ToppCell10x5'-Liver-Lymphocytic_NK-NK_CD16|Liver / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-06196535e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-0619653578b28b263deaa43590b38597186222c6447ad25f
ToppCellwk_20-22-Hematologic_Lymphocytic-NK-Intermediate_NK|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TGFBR3 IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-06196535a2f938022a080202bce5bb157d13b86b69054468
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK|lymph-node_spleen / Manually curated celltypes from each tissue

TGFBR3 IL12RB2 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-0619653593ff94fc2b2ca8bd6a6492cbc0b402daf5d63ea2
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-0619653577da6b1bcab45d376eb0368f540e0ed24ce98b42
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK|COVID-19_Severe / Disease group, lineage and cell class

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-06196535cc1daf12de5765ba4f7002396352404b41df2012
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD16|lymph-node_spleen / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-06196535f7e5a7fad4547e8ab9ab8b140239281832fb4260
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TGFBR3 KIR2DL1 KIR2DL3 KIR3DL1 RASGRP2

3.61e-06196535f424c45be7f34cbef76e1696dea10c1e3a9af2e0
ToppCellBL-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TGFBR3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

3.61e-06196535cfbeaabbeeb197f0cf8240a752d1f2995d59d7b7
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-061965353e78e307c9c991c1aadc85c61d401431cf75eaec
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-06196535f0566f2ef96584ed6d9247b149218376fb509915
ToppCellControl-Lymphocyte-T_NK-NK|Control / Disease, Lineage and Cell Type

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-0619653565838fddc920cdcecefe823f3ce1c95a7e50e82b
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-06196535d3bd8fab010e76024d7e06aba0ea5df3394f411f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-061965359b3848dd4256cd6d9a21ef6bfdbd0cb7c0030005
ToppCell10x5'-bone_marrow-Lymphocytic_NK-NK_CD16|bone_marrow / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-06196535a3b077e82b1550eb328c84b567b60179001f9a77
ToppCellCOVID-19_Severe-NK|World / disease group, cell group and cell class

TGFBR3 SYNE1 KIR3DL3 KIR2DL1 KIR2DL3

3.61e-06196535f46ca7cc2d8407d0dcaa77c4b16a2c1f2a23734d
ToppCell10x5'-bone_marrow-Lymphocytic_NK|bone_marrow / Manually curated celltypes from each tissue

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.61e-061965351868ad537b7f04cdad0a0c8282aadbc4f257a722
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell-NK|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.70e-0619753548311c7d85ffabf59fd1685c31c18b3e84a145b5
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.70e-061975359993fdea353abeafc009ac87439ad25cedf8f1f6
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.70e-06197535300849a922722adcbc068593fc5cc0bef936d9cb
ToppCellInfluenza_Severe-NK|World / Disease group and Cell class

TGFBR3 SYNE1 KIR2DL1 KIR2DL3 KIR3DL1

3.70e-06197535565d578f7a28a19175d56663bf30c60e0d5e1b22
ComputationalPorins / transporters.

TGFBR3 IL12RB2 KCNK1 KIR2DL3 KIR3DL1 CHRNA2 CHRNA4 CHRNB1

1.76e-07211338MODULE_63
ComputationalIon channels.

CLCN6 KCNK1 CHRNA2 CHRNA4 CHRNB1

2.09e-0670335MODULE_316
ComputationalAcetylCholine receptors.

CHRNA2 CHRNA4 CHRNB1

9.38e-0614333MODULE_328
ComputationalGenes in the cancer module 267.

CHRNA2 CHRNA4 CHRNB1

1.17e-0515333MODULE_267
ComputationalIon channels.

CHRNA2 CHRNA4 CHRNB1

7.33e-0527333MODULE_214
ComputationalNeighborhood of IL2RB

KIR3DL3 KIR2DL1 KIR3DL1

3.66e-0446333GNF2_IL2RB
ComputationalGenes in the cancer module 27.

TGFBR3 KIR2DL3 KIR3DL1 CHRNA2 CHRNA4 CHRNB1

6.47e-04355336MODULE_27
ComputationalGenes in the cancer module 138.

BMP7 MAT1A CHRNA2

2.34e-0387333MODULE_138
DrugAa1

SYNE1 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

3.48e-0883526CID009549188
Drugglycoluril

ALDH18A1 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.35e-0753525CID000062347
DrugD-Au

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

8.90e-0777525CID000277822
DrugEPTC

AASDH CHRNA2 CHRNA4 CHRNB1

1.20e-0635524CID000012968
DrugDns-C6-Cho

CHRNA2 CHRNA4 CHRNB1

1.83e-0611523CID000124728
DrugAC1L9NC9

CHRNA2 CHRNA4 CHRNB1

1.83e-0611523CID000449642
Drugdihydronereistoxin

CHRNA2 CHRNA4 CHRNB1

1.83e-0611523CID000121232
Drugbipinnatin-B

CHRNA2 CHRNA4 CHRNB1

1.83e-0611523CID000127363
DrugLJP 1082

CHRNA2 CHRNA4 CHRNB1

1.83e-0611523CID003037609
Drug2-methylmethionine

MET MAT1A MAT2A

2.44e-0612523CID000002111
DrugAC1L9P8C

CHRNA2 CHRNA4 CHRNB1

2.44e-0612523CID000450864
DrugSureCN373116

CHRNA2 CHRNA4 CHRNB1

2.44e-0612523CID010085732
Drugnereistoxin

CHRNA2 CHRNA4 CHRNB1

3.16e-0613523CID000015401
Drug1-acetyl-4-methylpiperazine methiodide

CHRNA2 CHRNA4 CHRNB1

3.16e-0613523CID004392675
DrugC-toxiferine-I

CHRNA2 CHRNA4 CHRNB1

3.16e-0613523CID005089093
Drugbipinnatin-C

CHRNA2 CHRNA4 CHRNB1

3.16e-0613523CID000129977
Drugbipinnatin-A

CHRNA2 CHRNA4 CHRNB1

3.16e-0613523CID000196603
Drug2,3-dichlorooctafluorobutane

CHRNA2 CHRNA4 CHRNB1

4.02e-0614523CID000078982
DrugLNF 209

CHRNA2 CHRNA4 CHRNB1

4.02e-0614523CID000132666
Drugoxotremorine

CLCN6 SYNE1 CHRNA2 CHRNA4 CHRNB1

4.76e-06108525CID000004630
Drugaa373

CHRNA2 CHRNA4 CHRNB1

5.01e-0615523CID000191672
Druganatoxin-a hydrochloride

CHRNA2 CHRNA4 CHRNB1

5.01e-0615523CID000135265
Drug(-)-pictamine

CHRNA2 CHRNA4 CHRNB1

5.01e-0615523CID006918623
Drug(-)-lepadin B

CHRNA2 CHRNA4 CHRNB1

5.01e-0615523CID006918624
DrugSAD-128

CHRNA2 CHRNA4 CHRNB1

5.01e-0615523CID000162008
DrugUB-165

CHRNA2 CHRNA4 CHRNB1

5.01e-0615523CID004694339
DrugN-methylcytisine

CHRNA2 CHRNA4 CHRNB1

5.01e-0615523CID000234566
Drug2-amino-4-methylthio-3-butenoic acid

MAT1A MAT2A

5.12e-062522ctd:C083253
DrugNabumetone [42924-53-8]; Up 200; 17.6uM; HL60; HT_HG-U133A

TGFBR3 KLF12 BMP7 CTC1 FAM135A CHRNB1

5.52e-061965263108_UP
Drug3-(trifluoromethyl)-3-(m-iodophenyl)diazirine

CHRNA2 CHRNA4 CHRNB1

6.16e-0616523CID000123866
DrugAC1L2SVN

CHRNA2 CHRNA4 CHRNB1

6.16e-0616523CID000127922
Drugbenzoquinonium

CHRNA2 CHRNA4 CHRNB1

6.16e-0616523CID000009393
DrugPNU-282,987

CHRNA2 CHRNA4 CHRNB1

6.16e-0616523CID004655349
DrugNsc36388

CHRNA2 CHRNA4 CHRNB1

7.47e-0617523CID000014954
DrugAC1O8PVM

CHRNA2 CHRNA4 CHRNB1

8.95e-0618523CID000004989
Drugbenzetimide

CHRNA2 CHRNA4 CHRNB1

8.95e-0618523CID000021846
DrugABT-594

CHRNA2 CHRNA4 CHRNB1

8.95e-0618523CID003075702
DrugAC1LCVGE

CHRNA2 CHRNA4 CHRNB1

8.95e-0618523CID000656712
DrugAC1L9P88

CHRNA2 CHRNA4 CHRNB1

1.06e-0519523CID000450860
Drugisoarecolone

CHRNA2 CHRNA4 CHRNB1

1.06e-0519523CID000146970
Drugbeta-erythroidine

CHRNA2 CHRNA4 CHRNB1

1.06e-0519523CID000010074
Drugperhydrohistrionicotoxin

CHRNA2 CHRNA4 CHRNB1

1.06e-0519523CID000107881
DrugPNU-120596

CHRNA2 CHRNA4 CHRNB1

1.06e-0519523CID000311434
Drug4-(N-maleimido)benzyltrimethylammonium

CHRNA2 CHRNA4 CHRNB1

1.06e-0519523CID000162425
DrugAC1Q5X7V

CHRNA2 CHRNA4 CHRNB1

1.25e-0520523CID000050190
Drug3-(2-azetidinylmethoxy)pyridine

CHRNA2 CHRNA4 CHRNB1

1.25e-0520523CID000001962
DrugDichloride, Alcuronium

CHRNA2 CHRNA4 CHRNB1

1.25e-0520523CID003032788
Drugpotassium

COL4A5 CLCN6 MAT2A SYNE1 KCNK1 AADAT CHRNA2 CHRNA4 SLC2A2 CHRNB1 GGT5

1.38e-0510085211CID000000813
DrugUltracet

HTR3E CHRNA2 CHRNA4 CHRNB1

1.39e-0564524CID000005523
Drugdinotefuran

CHRNA2 CHRNA4 CHRNB1

1.45e-0521523CID000197701
Drugmeproadifen

CHRNA2 CHRNA4 CHRNB1

1.45e-0521523CID000189752
DrugAb-9

KIR2DL2 KIR2DL3 KIR3DL1

1.45e-0521523CID006540280
DrugL-2-amino-4-methylthio-cis-but-3-enoic acid

MAT1A MAT2A

1.53e-053522CID006439623
Drugsazetidine-A

CHRNA2 CHRNA4

1.53e-053522ctd:C514816
Drugbenzylphosphate

MAT1A MAT2A

1.53e-053522CID000074359
Drugtetranitrofluorenone

MAT1A SYNE1

1.53e-053522CID000069780
Drugcarbaryl

G6PC2 CHRNA2 CHRNA4 CHRNB1

1.57e-0566524CID000006129
Drugsuberyldicholine

CHRNA2 CHRNA4 CHRNB1

1.68e-0522523CID000123989
DrugAR-R17779

CHRNA2 CHRNA4 CHRNB1

1.68e-0522523CID005310971
Drughistrionicotoxin

CHRNA2 CHRNA4 CHRNB1

1.68e-0522523CID005282247
Drugclothianidin

CHRNA2 CHRNA4 CHRNB1

1.68e-0522523CID000213027
DrugAC1L3BL8

CHRNA2 CHRNA4 CHRNB1

1.93e-0523523CID000086457
Drugalpha-conotoxin ImI

CHRNA2 CHRNA4 CHRNB1

1.93e-0523523CID000133011
DrugCID6325740

CHRNA2 CHRNA4 CHRNB1

1.93e-0523523CID006325740
DrugABT-418

CHRNA2 CHRNA4 CHRNB1

1.93e-0523523CID000119380
Drugalpha-conotoxin SI

CHRNA2 CHRNA4 CHRNB1

1.93e-0523523CID000163979
DrugSkpymrfamide

CHRNA2 CHRNA4 CHRNB1

1.93e-0523523CID000132661
Drugprocyclidine

CHRNA2 CHRNA4 CHRNB1

2.20e-0524523CID000004919
DrugAC1L2IZE

CHRNA2 CHRNA4 CHRNB1

2.20e-0524523CID000072928
Drugintruder

CHRNA2 CHRNA4 CHRNB1

2.20e-0524523CID000213021
Druganabaseine

CHRNA2 CHRNA4 CHRNB1

2.20e-0524523CID000018985
Drugarecoline

AASDH CHRNA2 CHRNA4 CHRNB1

2.22e-0572524CID000002230
Druganabasine

CHRNA2 CHRNA4 CHRNB1

2.49e-0525523CID000002181
Drugvarenicline

CHRNA2 CHRNA4 CHRNB1

2.49e-0525523CID000170361
DrugPrBCM

CHRNA2 CHRNA4 CHRNB1

2.49e-0525523CID000037396
Drugpempidine

CHRNA2 CHRNA4 CHRNB1

2.49e-0525523CID000006603
Drugbenzquinamide

CHRNA2 CHRNA4 CHRNB1

2.81e-0526523CID000002342
Drugbeta-eudesmol

CHRNA2 CHRNA4 CHRNB1

2.81e-0526523CID000091457
Drugcurarine

CHRNA2 CHRNA4 CHRNB1

2.81e-0526523CID000198004
Drugimidazolidine

CHRNA2 CHRNA4 CHRNB1

2.81e-0526523CID000449488
Drugbeta-erythroidine

CHRNA2 CHRNA4

3.06e-054522ctd:C004873
DrugNSC-187732

MAT1A MAT2A

3.06e-054522CID000302526
Drugvinthionine

MAT1A MAT2A

3.06e-054522CID000055145
Drugseleno-DL-ethionine

MAT1A MAT2A

3.06e-054522CID000145924
Drugmethylcarbamylcholine

CHRNA2 CHRNA4 CHRNB1

3.16e-0527523CID000004136
Drugnornicotine

CHRNA2 CHRNA4 CHRNB1

3.16e-0527523CID000000412
Drugoxotremorine-M

SYNE1 CHRNA2 CHRNA4 CHRNB1

3.53e-0581524CID000004629
Drugechothiophate

CHRNA2 CHRNA4 CHRNB1

3.54e-0528523CID000010547
Drugpentolinium

CHRNA2 CHRNA4 CHRNB1

3.54e-0528523CID000005849
DrugIno-Hcy

CHRNA2 CHRNA4 SLC2A2 CHRNB1

3.89e-0583524CID000193585
Drugbifemelane

CHRNA2 CHRNA4 CHRNB1

3.94e-0529523CID000002377
Drugbromoacetylcholine bromide

CHRNA2 CHRNA4 CHRNB1

3.94e-0529523CID000204966
Drugmetoclopramide

HTR3E CHRNA2 CHRNA4 CHRNB1

4.08e-0584524CID000004168
Drugvecuronium

CHRNA2 CHRNA4 CHRNB1

4.37e-0530523CID000039764
Drugmethylenedioxydimethylamphetamine

CHRNA2 CHRNA4 CHRNB1

4.37e-0530523CID000551630
Drug6-carboxyfluorescein diacetate

KIR2DL1 KIR2DL2 KIR2DL3

4.37e-0530523CID000151095
DrugDL-ethionine

FAT1 MAT1A MAT2A GGT5

4.68e-0587524CID000006205
Drugtetrahydrodeoxycortisol

CHRNA2 CHRNA4 CHRNB1

4.83e-0531523CID000010593
DrugAC1L1JK6

CHRNA2 CHRNA4 CHRNB1

4.83e-0531523CID000005077
Drugquinuclidine

CHRNA2 CHRNA4 CHRNB1

4.83e-0531523CID000007527
Diseaselevel of killer cell immunoglobulin-like receptor 2DS2 in blood serum

KIR3DL3 KIR2DL1 KIR2DL3

4.30e-093493OBA_2042107
Diseasecerebral palsy (implicated_via_orthology)

AGAP7P AGAP4 AGAP6

5.12e-0710493DOID:1969 (implicated_via_orthology)
Diseasekiller cell immunoglobulin-like receptor 2DS2 measurement

KIR3DL3 KIR2DL1 KIR2DL3

1.93e-0615493EFO_0801746
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

CHRNA2 CHRNA4 CHRNB1

2.37e-0616493DOID:3635 (implicated_via_orthology)
Diseasegastrinoma (is_marker_for)

MET SLC2A2

8.10e-063492DOID:5577 (is_marker_for)
DiseaseAutosomal dominant nocturnal frontal lobe epilepsy

CHRNA2 CHRNA4

1.62e-054492cv:C3696898
DiseaseAutosomal Dominant Nocturnal Frontal Lobe Epilepsy

CHRNA2 CHRNA4

5.64e-057492C3696898
DiseaseHOMA-B

TGFBR3 G6PC2 SLC2A2

1.06e-0455493EFO_0004469
Diseasefasting blood glucose measurement

BMP7 FAT3 GALNT9 G6PC2 SLC2A2

1.13e-04287495EFO_0004465
Diseaselipid metabolism disorder (implicated_via_orthology)

MAT1A MAT2A

2.80e-0415492DOID:3146 (implicated_via_orthology)
DiseaseBMI-adjusted fasting blood glucose measurement

G6PC2 SLC2A2

6.68e-0423492EFO_0008036
DiseaseBrain Diseases

CTC1 MAT1A

7.91e-0425492C0006111
DiseaseEncephalopathies

CTC1 MAT1A

9.23e-0427492C0085584
DiseaseHyperplasia

MAT1A KCNK1

9.93e-0428492C0020507
Diseasecoenzyme Q10 measurement

KLF12 BCR

1.64e-0336492EFO_0007836

Protein segments in the cluster

PeptideGeneStartEntry
IISVTLEIPHHITQR

AGAP4

141

Q96P64
IVITVFVLNVHHRSP

CHRNA4

321

P43681
IERVILHIQVSTLHP

AADAT

281

Q8N5Z0
RSHPAVTHVSIIVQV

CTC1

251

Q2NKJ3
TVVQRFHEHVHQPSV

ACOX3

566

O15254
TIFITHLLHVATTQP

HTR3E

326

A5X5Y0
RHRHCPVVVSEATIV

BCR

391

P11274
LSIVITVFVLNVHHR

CHRNA2

341

Q15822
FSVILSVVVLNLHHR

CHRNB1

321

P11230
VLFSHHRVTVLQATP

AASDH

276

Q4L235
RLTHVQFNLIHPIII

DNAI1

631

Q9UI46
STNPVHAVDVVLRHL

AGO3

156

Q9H9G7
HAIVQTLVHFINPET

BMP7

376

P18075
KIVHQVRAAIHTPRF

ARRDC1

106

Q8N5I2
IISVTLEIPHHITQR

AGAP6

141

Q5VW22
IAESIQVHSPVVHVQ

FAT1

2191

Q14517
PRHLHILIGTSVVII

KIR2DL2

241

P43627
TAPQRALVITHFVHV

RASGRP2

216

Q7LDG7
PRHLHVLIGTSVVII

KIR2DL3

241

P43628
VHVVHQIPAVSVTSV

FOXK2

471

Q01167
VILRSVHSVVNHTPS

GALNT9

166

Q9HCQ5
LPIRVHTIVISVQHD

MAT2A

196

P31153
ITVHVTRRPVLYFHI

KCNK1

156

O00180
VISEVLHQVTPVFRH

IL12RB2

706

Q99665
PRHLHILIGTSVVII

KIR3DL1

336

P43629
VTVHASLVALHQPLI

FAM135A

166

Q9P2D6
VAIRNPLHYVSILTH

OR51H1

126

Q8NH63
HLHVLIGTSVVIIPF

KIR3DL3

321

Q8N743
QVIISHYRHVLGVPL

SLC2A2

36

P11168
IPVRIHTIVISVQHN

MAT1A

196

Q00266
IQESVLEHFRTHPTV

MMAA

371

Q8IVH4
VVHRFARHVSPLINV

OR51A4

261

Q8NGJ6
HRRSQVLVEHVVPAS

NKD2

296

Q969F2
VFRSHCIQPSVIRHV

ALDH18A1

26

P54886
LVSILRTTVHHAFPV

CLCN6

621

P51797
RTTVHHAFPVVTENR

CLCN6

626

P51797
AVVIAVHSQTIQIPH

COL4A5

1571

P29400
IERINEHAPTIHVVT

FAT3

256

Q8TDW7
AVIVLAVVLSRHQAP

GGT5

21

P36269
IISVTLEIPHHITQR

AGAP7P

141

Q5VUJ5
ISRVFIATHFPHQVI

G6PC2

166

Q9NQR9
AHVLHLRGVLTTQPV

ASNSD1

51

Q9NWL6
VQHVIHYQVPRTSEI

DDX24

656

Q9GZR7
QSNKLSHVHRIPVVV

KLF12

176

Q9Y4X4
SHVHRIPVVVQSVPV

KLF12

181

Q9Y4X4
PRHLHILIGTSVVII

KIR2DL1

241

P43626
VQHVVIGPSSLIVHF

MET

1066

P08581
TEAVVITQVCHPHRI

TDRD6

251

O60522
VAFHSVIHAIRPELV

SYNE1

211

Q8NF91
FEALQVHREVIPTHT

TADA1

281

Q96BN2
HHVVRVPHTQAVVLN

PI4KB

376

Q9UBF8
ITHHAVILFVLVPVA

TLCD3A

121

Q8TBR7
ELQTHTFPITIIHGV

ZGRF1

1641

Q86YA3
REVTLHLNPISSVHI

TGFBR3

81

Q03167
SVRNIFHLFHDVVPT

ZW10

511

O43264