Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin-like ligase-substrate adaptor activity

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

1.28e-108295GO:1990756
GeneOntologyMolecularFunctionenzyme-substrate adaptor activity

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

2.72e-109595GO:0140767
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

6.42e-095594GO:0042974
GeneOntologyMolecularFunctionnuclear receptor binding

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

9.05e-0718794GO:0016922
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

2.17e-0541794GO:0061629
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

6.79e-05116095GO:0030674
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

8.01e-0558294GO:0140297
GeneOntologyMolecularFunctionmolecular adaptor activity

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

1.43e-04135695GO:0060090
GeneOntologyMolecularFunctiontranscription factor binding

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

2.17e-0475394GO:0008134
GeneOntologyBiologicalProcessnegative regulation of cell differentiation

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

1.04e-06875106GO:0045596
GeneOntologyBiologicalProcessnegative regulation of apoptotic process

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

4.70e-061133106GO:0043066
GeneOntologyBiologicalProcessnegative regulation of programmed cell death

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

5.70e-061171106GO:0043069
GeneOntologyBiologicalProcessblastocyst formation

PRAMEF11 PRAMEF4 PRAMEF15

6.12e-0678103GO:0001825
GeneOntologyBiologicalProcesspositive regulation of cell population proliferation

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

6.26e-061190106GO:0008284
GeneOntologyBiologicalProcessnegative regulation of developmental process

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

7.23e-061220106GO:0051093
GeneOntologyBiologicalProcessoocyte development

PRAMEF11 PRAMEF4 PRAMEF15

1.26e-0599103GO:0048599
GeneOntologyBiologicalProcessoocyte differentiation

PRAMEF11 PRAMEF4 PRAMEF15

1.41e-05103103GO:0009994
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

1.60e-051399106GO:0045892
GeneOntologyBiologicalProcesssomatic stem cell population maintenance

PRAMEF11 PRAMEF4 PRAMEF15

1.63e-05108103GO:0035019
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

1.69e-051413106GO:1902679
GeneOntologyBiologicalProcessoogenesis

PRAMEF11 PRAMEF4 PRAMEF15

4.90e-05156103GO:0048477
GeneOntologyBiologicalProcessblastocyst development

PRAMEF11 PRAMEF4 PRAMEF15

7.37e-05179103GO:0001824
GeneOntologyBiologicalProcessfemale gamete generation

PRAMEF11 PRAMEF4 PRAMEF15

1.41e-04223103GO:0007292
GeneOntologyBiologicalProcessstem cell population maintenance

PRAMEF11 PRAMEF4 PRAMEF15

1.69e-04237103GO:0019827
GeneOntologyBiologicalProcessmaintenance of cell number

PRAMEF11 PRAMEF4 PRAMEF15

1.80e-04242103GO:0098727
GeneOntologyBiologicalProcessregulation of ERK1 and ERK2 cascade

PRAMEF11 PRAMEF4 PRAMEF15

7.02e-04385103GO:0070372
GeneOntologyBiologicalProcessERK1 and ERK2 cascade

PRAMEF11 PRAMEF4 PRAMEF15

8.92e-04418103GO:0070371
GeneOntologyBiologicalProcessgerm cell development

PRAMEF11 PRAMEF4 PRAMEF15

1.35e-03482103GO:0007281
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

PRAMEF11 PRAMEF4 PRAMEF15

1.74e-03527103GO:0022412
GeneOntologyBiologicalProcessin utero embryonic development

PRAMEF11 PRAMEF4 PRAMEF15

2.47e-03596103GO:0001701
GeneOntologyBiologicalProcessregulation of MAPK cascade

PRAMEF11 PRAMEF4 PRAMEF15

5.99e-03815103GO:0043408
GeneOntologyBiologicalProcesschordate embryonic development

PRAMEF11 PRAMEF4 PRAMEF15

8.04e-03906103GO:0043009
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

PRAMEF11 PRAMEF4 PRAMEF15

8.61e-03929103GO:0009792
GeneOntologyBiologicalProcessMAPK cascade

PRAMEF11 PRAMEF4 PRAMEF15

8.64e-03930103GO:0000165
GeneOntologyBiologicalProcessgamete generation

PRAMEF11 PRAMEF4 PRAMEF15

1.00e-02982103GO:0007276
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

PRAMEF11 PRAMEF4 PRAMEF15

1.71e-021194103GO:0048609
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

1.15e-1147105GO:0031462
GeneOntologyCellularComponentcullin-RING ubiquitin ligase complex

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

2.47e-08212105GO:0031461
GeneOntologyCellularComponentubiquitin ligase complex

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

3.09e-07352105GO:0000151
GeneOntologyCellularComponentacrosomal vesicle

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15

1.84e-06206104GO:0001669
GeneOntologyCellularComponentmotile cilium

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15

1.58e-05355104GO:0031514
GeneOntologyCellularComponenttransferase complex

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

4.26e-05963105GO:1990234
GeneOntologyCellularComponentintracellular protein-containing complex

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

4.46e-05972105GO:0140535
GeneOntologyCellularComponentcilium

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15

5.77e-04898104GO:0005929
GeneOntologyCellularComponentsecretory granule

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15

9.13e-041014104GO:0030141
GeneOntologyCellularComponentsecretory vesicle

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15

1.97e-031246104GO:0099503
GeneOntologyCellularComponentchromatin

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

3.72e-031480104GO:0000785
MousePhenoabnormal spermatogonia proliferation

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.67e-094764MP:0002685
MousePhenodecreased testis weight

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

7.43e-0837065MP:0004852
MousePhenoabnormal testis weight

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

9.79e-0839165MP:0004850
MousePhenoabnormal jejunum morphology

PRAMEF11 PRAMEF4 PRAMEF15

4.66e-074163MP:0004002
MousePhenoincreased male germ cell apoptosis

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

4.75e-0718964MP:0014052
MousePhenoabnormal sperm number

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.01e-0662465MP:0002673
MousePhenodecreased male germ cell number

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.14e-0664065MP:0004901
MousePhenoabnormal male germ cell apoptosis

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.16e-0623664MP:0008280
MousePhenoabnormal male germ cell physiology

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.32e-0624464MP:0020362
MousePhenoazoospermia

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.32e-0624464MP:0005159
MousePhenoabsent gametes

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.60e-0625664MP:0001117
MousePhenodecreased germ cell number

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.63e-0668765MP:0002209
MousePhenoabnormal duodenum morphology

PRAMEF11 PRAMEF4 PRAMEF15

1.81e-066463MP:0003271
MousePhenoabnormal germ cell physiology

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.89e-0626764MP:0020363
MousePhenoabnormal gametes

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

3.16e-0678565MP:0001124
MousePhenosmall testis

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

3.99e-0682365MP:0001147
MousePhenoabnormal male germ cell morphology

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

4.93e-0685965MP:0006362
MousePhenosmall gonad

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

5.72e-0688565MP:0001116
MousePhenoabnormal primary sex determination

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

6.25e-0690165MP:0002211
MousePhenoabnormal spermatogenesis

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

6.57e-0691065MP:0001156
MousePhenoabnormal testis size

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

6.75e-0691565MP:0004849
MousePhenoabnormal cecum morphology

PRAMEF11 PRAMEF4 PRAMEF15

6.79e-069963MP:0000494
MousePhenomale infertility

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

7.88e-0694465MP:0001925
MousePhenoabnormal sex determination

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

7.92e-0694565MP:0002210
MousePhenoabnormal germ cell morphology

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

7.96e-0694665MP:0002208
MousePhenoabnormal foam cell morphology

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

8.30e-0695465MP:0009840
MousePhenoenlarged urinary bladder

PRAMEF11 PRAMEF4 PRAMEF15

1.09e-0511663MP:0011874
MousePhenoincreased circulating amylase level

PRAMEF11 PRAMEF4 PRAMEF15

1.18e-0511963MP:0008806
MousePhenoabnormal vitreous body morphology

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.25e-0542964MP:0002699
MousePhenoabnormal gametogenesis

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.46e-05107065MP:0001929
MousePhenoabnormal testis morphology

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.54e-05108165MP:0001146
MousePhenoincreased kidney weight

PRAMEF11 PRAMEF4 PRAMEF15

2.14e-0514563MP:0003917
MousePhenocataract

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

2.24e-0549764MP:0001304
MousePhenoinfertility

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

2.45e-05118865MP:0001924
MousePhenoabnormal circulating amylase level

PRAMEF11 PRAMEF4 PRAMEF15

2.66e-0515663MP:0008804
MousePhenoabnormal male reproductive gland morphology

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

3.68e-05129065MP:0013325
MousePhenoabnormal cell proliferation

INCA1 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

3.74e-05129465MP:0000350
MousePhenoabnormal male reproductive system physiology

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

4.26e-05132965MP:0003698
MousePhenoabnormal small intestine morphology

PRAMEF11 PRAMEF4 PRAMEF15

4.57e-0518763MP:0000496
MousePhenoabnormal internal male genitalia morphology

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

5.35e-05139265MP:0009205
MousePhenoabnormal male reproductive system morphology

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

5.80e-05141565MP:0001145
MousePhenoabnormal male genitalia morphology

CFAP119 PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

5.80e-05141565MP:0009198
MousePhenoabnormal kidney weight

PRAMEF11 PRAMEF4 PRAMEF15

6.28e-0520863MP:0002707
MousePhenoabnormal lens morphology

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

8.58e-0569964MP:0001303
MousePhenoabnormal urinary bladder morphology

PRAMEF11 PRAMEF4 PRAMEF15

1.05e-0424763MP:0000538
MousePhenoabnormal stomach morphology

PRAMEF11 PRAMEF4 PRAMEF15

1.06e-0424863MP:0000470
MousePhenoabnormal large intestine morphology

PRAMEF11 PRAMEF4 PRAMEF15

1.46e-0427663MP:0000489
MousePhenoabnormal seminal vesicle morphology

PRAMEF11 PRAMEF4 PRAMEF15

2.24e-0431963MP:0002059
MousePhenoenlarged kidney

PRAMEF11 PRAMEF4 PRAMEF15

3.04e-0435463MP:0003068
MousePhenoabnormal male accessory sex gland morphology

PRAMEF11 PRAMEF4 PRAMEF15

3.15e-0435863MP:0013330
MousePhenoabnormal pancreas morphology

PRAMEF11 PRAMEF4 PRAMEF15

3.38e-0436763MP:0001944
MousePhenoincreased apoptosis

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

3.58e-04100864MP:0006042
MousePhenoincreased cell death

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

3.74e-04101964MP:0012556
MousePhenoabnormal tail morphology

PRAMEF11 PRAMEF4 PRAMEF15

4.46e-0440363MP:0002111
MousePhenoincreased circulating alanine transaminase level

PRAMEF11 PRAMEF4 PRAMEF15

4.76e-0441263MP:0002941
MousePhenosmall kidney

PRAMEF11 PRAMEF4 PRAMEF15

5.21e-0442563MP:0002989
MousePhenoabnormal anterior eye segment morphology

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

5.34e-04111764MP:0005193
MousePhenoabnormal circulating alanine transaminase level

PRAMEF11 PRAMEF4 PRAMEF15

8.29e-0449863MP:0001573
MousePhenoenlarged lymph nodes

PRAMEF11 PRAMEF4 PRAMEF15

8.74e-0450763MP:0000702
MousePhenodecreased exploration in new environment

PRAMEF11 PRAMEF4 PRAMEF15

8.89e-0451063MP:0001417
MousePhenoabnormal intestine morphology

PRAMEF11 PRAMEF4 PRAMEF15

1.09e-0354663MP:0000477
MousePhenoabnormal apoptosis

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.12e-03135364MP:0001648
MousePhenoabnormal programmed cell death

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.14e-03136064MP:0014355
MousePhenoabnormal lymph node size

PRAMEF11 PRAMEF4 PRAMEF15

1.17e-0356163MP:0000701
MousePhenoabnormal auditory brainstem response

PRAMEF11 PRAMEF4 PRAMEF15

1.27e-0357663MP:0004738
MousePhenoabnormal hearing electrophysiology

PRAMEF11 PRAMEF4 PRAMEF15

1.39e-0359463MP:0006335
MousePhenoabnormal skin morphology

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.48e-03145564MP:0002060
MousePhenoabnormal hearing physiology

PRAMEF11 PRAMEF4 PRAMEF15

1.75e-0364363MP:0001963
MousePhenoabnormal exploration in a new environment

PRAMEF11 PRAMEF4 PRAMEF15

1.78e-0364763MP:0013189
MousePhenoabnormal lymph node morphology

PRAMEF11 PRAMEF4 PRAMEF15

2.08e-0368363MP:0002339
MousePhenoabnormal ear physiology

PRAMEF11 PRAMEF4 PRAMEF15

2.09e-0368463MP:0003878
MousePhenoabnormal response to new environment

PRAMEF11 PRAMEF4 PRAMEF15

2.11e-0368763MP:0001413
MousePhenoabnormal kidney size

PRAMEF11 PRAMEF4 PRAMEF15

2.36e-0371463MP:0002706
MousePhenoabnormal response to novelty

PRAMEF11 PRAMEF4 PRAMEF15

3.13e-0378763MP:0003107
MousePhenoabnormal exocrine gland morphology

PRAMEF11 PRAMEF4 PRAMEF15

3.94e-0385363MP:0013558
MousePhenoenlarged spleen

PRAMEF11 PRAMEF4 PRAMEF15

4.06e-0386263MP:0000691
MousePhenohearing/vestibular/ear phenotype

PRAMEF11 PRAMEF4 PRAMEF15

4.66e-0390563MP:0005377
MousePhenoenlarged heart

PRAMEF11 PRAMEF4 PRAMEF15

4.83e-0391663MP:0000274
MousePhenovisceromegaly

PRAMEF11 PRAMEF4 PRAMEF15

6.74e-03103063MP:0013328
MousePhenoincreased circulating enzyme level

PRAMEF11 PRAMEF4 PRAMEF15

8.97e-03114063MP:0014450
MousePhenoincreased enzyme/coenzyme level

PRAMEF11 PRAMEF4 PRAMEF15

9.14e-03114863MP:0014448
MousePhenoabnormal heart size

PRAMEF11 PRAMEF4 PRAMEF15

9.88e-03118063MP:0005406
MousePhenoabnormal spleen size

PRAMEF11 PRAMEF4 PRAMEF15

1.04e-02120363MP:0002224
MousePhenoabnormal digestive system morphology

PRAMEF11 PRAMEF4 PRAMEF15

1.12e-02123363MP:0000462
MousePhenoabnormal learning/memory/conditioning

PRAMEF11 PRAMEF4 PRAMEF15

1.13e-02123963MP:0002063
MousePhenoabnormal cognition

PRAMEF11 PRAMEF4 PRAMEF15

1.15e-02124663MP:0014114
MousePhenolimbs/digits/tail phenotype

PRAMEF11 PRAMEF4 PRAMEF15

1.18e-02125863MP:0005371
MousePhenoabnormal kidney morphology

PRAMEF11 PRAMEF4 PRAMEF15

1.48e-02136363MP:0002135
MousePhenoabnormal circulating enzyme level

PRAMEF11 PRAMEF4 PRAMEF15

1.50e-02137263MP:0001570
MousePhenoincreased circulating protein level

PRAMEF11 PRAMEF4 PRAMEF15

1.69e-02143363MP:0014501
MousePhenoabnormal enzyme/coenzyme level

PRAMEF11 PRAMEF4 PRAMEF15

1.75e-02145163MP:0005319
MousePhenodigestive/alimentary phenotype

PRAMEF11 PRAMEF4 PRAMEF15

1.92e-02150063MP:0005381
DomainPRAME_family

PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF27

5.34e-111984IPR026271
Domain-

PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF27

5.68e-06321843.80.10.10
DomainL_dom-like

PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF27

6.18e-0632884IPR032675
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.67e-112010426694250
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

2.51e-112210431729367
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

4.35e-112510437451217
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

7.03e-112810425089626
Pubmed

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.80e-103510419389355
Pubmed

Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.

PRAMEF11 PRAMEF4 PRAMEF15

1.16e-081710323565261
Pubmed

Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.

PRAMEF11 PRAMEF4 PRAMEF15

1.16e-081710337781892
Pubmed

Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.

PRAMEF11 PRAMEF4 PRAMEF15

1.39e-081810339181896
Pubmed

Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.

PRAMEF11 PRAMEF4 PRAMEF15

1.39e-081810312890732
Pubmed

Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.

PRAMEF11 PRAMEF4 PRAMEF15

1.39e-081810314675769
Pubmed

Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.

PRAMEF11 PRAMEF4 PRAMEF15

1.39e-081810329731491
Pubmed

The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.

PRAMEF11 PRAMEF4 PRAMEF15

1.39e-081810323894331
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF11 PRAMEF4 PRAMEF15

1.65e-081910328604677
Pubmed

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.

PRAMEF11 PRAMEF4 PRAMEF15

1.95e-082010321425410
Pubmed

Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.

PRAMEF11 PRAMEF4 PRAMEF15

1.95e-082010316580637
Pubmed

Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.

PRAMEF11 PRAMEF4 PRAMEF15

3.02e-082310319480014
Pubmed

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.

PRAMEF11 PRAMEF4 PRAMEF15

3.92e-082510312620990
Pubmed

Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.

PRAMEF11 PRAMEF4 PRAMEF15

4.43e-082610318500982
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

PRAMEF11 PRAMEF4 PRAMEF15

6.92e-083010338786026
Pubmed

LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.

PRAMEF11 PRAMEF4 PRAMEF15

8.45e-083210337889087
Pubmed

Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.

PRAMEF11 PRAMEF4 PRAMEF15

2.58e-074610317287250
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

PRAMEF11 PRAMEF4 PRAMEF15

3.33e-075010331806660
Pubmed

ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.

PRAMEF11 PRAMEF4 PRAMEF15

5.24e-075810331598710
Pubmed

An abundance of X-linked genes expressed in spermatogonia.

PRAMEF11 PRAMEF4 PRAMEF15

5.52e-075910311279525
Pubmed

Maternal microRNAs are essential for mouse zygotic development.

PRAMEF11 PRAMEF4 PRAMEF15

5.51e-0527310317369397
Pubmed

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.

PRAMEF11 PRAMEF4 PRAMEF15

9.33e-0532610317015433
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

PRAMEF11 PRAMEF4 PRAMEF15

1.12e-0434710316033648
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

PRAMEF11 PRAMEF4 PRAMEF15

1.28e-0436310314691545
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF9

1.40e-04103110416710414
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

PRAMEF11 PRAMEF4 PRAMEF15

2.03e-0442410321731673
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

PRAMEF11 PRAMEF4 PRAMEF15

4.68e-0456410321565611
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

PRAMEF11 PRAMEF4 PRAMEF15

7.85e-0467410337196079
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PRAMEF11 PRAMEF4 PRAMEF15

3.07e-03108410311544199
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

PRAMEF11 PRAMEF4 PRAMEF15

4.52e-03124210330973865
InteractionPRAMEF4 interactions

PRAMEF4 PRAMEF9

4.14e-07382int:PRAMEF4
InteractionPRAMEF5 interactions

PRAMEF4 PRAMEF15

3.86e-06882int:PRAMEF5
InteractionPRAMEF9 interactions

PRAMEF4 PRAMEF9

1.07e-051382int:PRAMEF9
Cytoband1p36.21

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9

1.04e-12631051p36.21
CytobandEnsembl 112 genes in cytogenetic band chr1p36

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

2.08e-09681106chr1p36
GeneFamilyPRAME family

PRAMEF11 PRAMEF25 PRAMEF4 PRAMEF15 PRAMEF9 PRAMEF27

7.76e-172486686
CoexpressionKOHOUTEK_CCNT2_TARGETS

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.05e-088194MM938
CoexpressionINGRAM_SHH_TARGETS_UP

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

1.49e-0715694MM550
CoexpressionKINNEY_DNMT1_METHYLATION_TARGETS

PRAMEF11 PRAMEF4 PRAMEF15

1.67e-073493MM955
CoexpressionYAMAZAKI_TCEB3_TARGETS_DN

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF27

7.28e-0723294MM1019
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED

PRAMEF11 PRAMEF4 PRAMEF15

8.11e-075793MM1262
CoexpressionMIKKELSEN_ES_ICP_WITH_H3K4ME3

PRAMEF11 PRAMEF4 PRAMEF15 DNAJC4 PRAMEF27

3.11e-0680795MM855
CoexpressionMORI_SMALL_PRE_BII_LYMPHOCYTE_UP

PRAMEF11 PRAMEF4 PRAMEF15

4.19e-069893MM592
CoexpressionDESCARTES_ORGANOGENESIS_SCHWANN_CELL_PRECURSOR

PRAMEF11 PRAMEF4 PRAMEF15

4.19e-069893MM3656
CoexpressionHUANG_GATA2_TARGETS_DN

PRAMEF11 PRAMEF4 PRAMEF15

4.19e-069893MM942
CoexpressionMIKKELSEN_NPC_ICP_WITH_H3K4ME3

PRAMEF11 PRAMEF4 PRAMEF15 DNAJC4

1.49e-0549794MM863
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS

PRAMEF11 PRAMEF4 PRAMEF15

2.60e-0518093MM612
CoexpressionSANSOM_APC_TARGETS

PRAMEF11 PRAMEF4 PRAMEF15

6.50e-0524593MM735
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

PRAMEF11 PRAMEF4 PRAMEF15

7.84e-0526193MM1277
CoexpressionYAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN

PRAMEF11 PRAMEF4 PRAMEF15

1.29e-0430993MM1244
CoexpressionFOSTER_KDM1A_TARGETS_UP

PRAMEF11 PRAMEF4 PRAMEF15

1.39e-0431793MM956
CoexpressionKUMAR_TARGETS_OF_MLL_AF9_FUSION

PRAMEF11 PRAMEF4 PRAMEF15

4.25e-0446393MM1011
CoexpressionMARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN

PRAMEF11 PRAMEF4 PRAMEF15

6.77e-0454393MM997
CoexpressionMEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED

PRAMEF11 PRAMEF4 PRAMEF15

7.95e-0457493MM820
CoexpressionHAY_BONE_MARROW_DENDRITIC_CELL

CFAP119 DNAJC4

1.95e-0319792M39194
CoexpressionGSE27786_LSK_VS_MONO_MAC_DN

CFAP119 DNAJC4

2.01e-0320092M4765
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS

PRAMEF11 PRAMEF4 PRAMEF15

2.64e-0387193MM1005
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

PRAMEF11 PRAMEF4 PRAMEF15

5.44e-03112493MM1070
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Monophasic_Synovial_Sarcoma-5|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

PRAMEF11 PRAMEF4 PRAMEF15 PRAMEF9

3.56e-09931043e05ea0f8f4a7cdb78a596f47d563dc3c94d4d8e
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-2|TCGA-Cervix / Sample_Type by Project: Shred V9

PRAMEF11 PRAMEF4

2.18e-04100102309e1600d21f3be97b48d183306b9115eb75e6a3
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-7|TCGA-Cervix / Sample_Type by Project: Shred V9

PRAMEF9 PRAMEF27

2.31e-0410310292924a8a7cbfc15f7ff74286d9abd54fc9c1b1bc
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-5|TCGA-Stomach / Sample_Type by Project: Shred V9

PRAMEF11 PRAMEF27

2.44e-041061024bee154c8b984338c06f73bd6e3fb26abce0bd72
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Embryonal_Carcinoma|TCGA-Testes / Sample_Type by Project: Shred V9

PRAMEF15 PRAMEF27

4.20e-041391026b58d01ce9d9ac23434333f9faf1bb0eef14ba90
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PRAMEF4 PRAMEF9

5.48e-04159102916d070d099726f22deb71966efccff00f8ea071
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRAMEF4 PRAMEF9

5.48e-041591026599707107083af6da092fe8984afc8fd89d2bb8
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-7|TCGA-Kidney / Sample_Type by Project: Shred V9

INCA1 CFAP119

5.97e-04166102b545de32578047c9ca422354b8992f2d9c9e1cc7

Protein segments in the cluster

PeptideGeneStartEntry
LLQKLPPRLQWKRPP

CAPN14

61

A8MX76
WPFRRLPLRPLIKMP

PRAMEF15

61

P0DUQ1
LFPPPLPRPRICMWK

CFAP119

66

A1A4V9
MPPLLPLRLCRLWPR

DNAJC4

1

Q9NNZ3
QLPPPEMLWRRKKRR

INCA1

81

Q0VD86
WPFRRLPLRPLIKMP

PRAMEF25

61

A6NGN4
WPFRRLPLRPLIKMP

PRAMEF27

61

A3QJZ7
WPFRRLPLRPLIKMP

PRAMEF4

61

O60810
WPFRRLPLRPLIKMP

PRAMEF9

61

P0DUQ2
WPFRRLPLRPLIKMP

PRAMEF11

61

O60813