Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	TRPM6 SLC12A6 GPR89B SLC8A2 SLC8A3 PIEZO2 CLCN3 SLC37A3 CLCN4 CLCN5 ABCA12 SV2B GLRA1 SCN7A SLC22A15 SCN8A HRH1 GPR89A ATP13A5 CACNA1I LRRC8B MFSD4B SLC1A7 ATP6V0A2 XPR1	1.09e-13	1180	71	25	GO:0022857
GeneOntologyMolecularFunction	transporter activity	TRPM6 SLC12A6 GPR89B SLC8A2 SLC8A3 PIEZO2 CLCN3 SLC37A3 CLCN4 CLCN5 ABCA12 SV2B GLRA1 SCN7A SLC22A15 SCN8A HRH1 GPR89A ATP13A5 CACNA1I LRRC8B MFSD4B SLC1A7 ATP6V0A2 XPR1	7.88e-13	1289	71	25	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	TRPM6 SLC12A6 GPR89B SLC8A2 SLC8A3 PIEZO2 CLCN3 CLCN4 CLCN5 GLRA1 SCN7A SCN8A HRH1 GPR89A ATP13A5 CACNA1I LRRC8B SLC1A7 ATP6V0A2	2.40e-11	793	71	19	GO:0015075
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	GPR89B CLCN3 CLCN4 CLCN5 GPR89A	2.95e-09	17	71	5	GO:0008308
GeneOntologyMolecularFunction	monoatomic anion channel activity	GPR89B CLCN3 CLCN4 CLCN5 GLRA1 GPR89A LRRC8B SLC1A7	3.09e-09	103	71	8	GO:0005253
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC12A6 GPR89B CLCN3 CLCN4 CLCN5 GLRA1 GPR89A LRRC8B SLC1A7	3.18e-09	151	71	9	GO:0008509
GeneOntologyMolecularFunction	channel activity	TRPM6 SLC12A6 GPR89B PIEZO2 CLCN3 CLCN4 CLCN5 GLRA1 SCN7A SCN8A GPR89A CACNA1I LRRC8B SLC1A7	3.87e-09	525	71	14	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TRPM6 SLC12A6 GPR89B PIEZO2 CLCN3 CLCN4 CLCN5 GLRA1 SCN7A SCN8A GPR89A CACNA1I LRRC8B SLC1A7	3.96e-09	526	71	14	GO:0022803
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	TRPM6 SLC12A6 SLC8A2 SLC8A3 CLCN3 SLC37A3 CLCN4 CLCN5 GLRA1 SCN7A SCN8A HRH1 CACNA1I SLC1A7 ATP6V0A2 XPR1	7.23e-09	758	71	16	GO:0015318
GeneOntologyMolecularFunction	monoatomic ion channel activity	TRPM6 GPR89B PIEZO2 CLCN3 CLCN4 CLCN5 GLRA1 SCN7A SCN8A GPR89A CACNA1I LRRC8B SLC1A7	7.30e-09	459	71	13	GO:0005216
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC12A6 SLC8A2 SLC8A3 CLCN3 SLC37A3 CLCN4 CLCN5 ABCA12 ATP13A5 MFSD4B SLC1A7 ATP6V0A2 XPR1	1.15e-08	477	71	13	GO:0022804
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC12A6 SLC8A2 SLC8A3 CLCN3 SLC37A3 CLCN4 CLCN5 MFSD4B SLC1A7 XPR1	9.15e-08	296	71	10	GO:0015291
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC12A6 CLCN3 SLC37A3 CLCN4 CLCN5 GLRA1 SLC1A7 XPR1	1.65e-07	171	71	8	GO:0015103
GeneOntologyMolecularFunction	gated channel activity	GPR89B PIEZO2 CLCN3 CLCN4 CLCN5 GLRA1 SCN7A GPR89A CACNA1I SLC1A7	2.80e-07	334	71	10	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	TRPM6 SLC12A6 SLC8A2 SLC8A3 PIEZO2 SCN7A SCN8A HRH1 ATP13A5 CACNA1I SLC1A7 ATP6V0A2	3.52e-06	664	71	12	GO:0008324
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	SLC12A6 CLCN3 CLCN4 CLCN5 GLRA1 SLC1A7	5.48e-06	125	71	6	GO:0015108
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCN3 CLCN4 CLCN5	6.96e-06	11	71	3	GO:0005247
GeneOntologyMolecularFunction	antiporter activity	SLC8A2 SLC8A3 CLCN3 SLC37A3 CLCN4 CLCN5	9.68e-06	138	71	6	GO:0015297
GeneOntologyMolecularFunction	chloride channel activity	CLCN3 CLCN4 CLCN5 GLRA1 SLC1A7	1.37e-05	86	71	5	GO:0005254
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC8A2 SLC8A3 SCN7A SCN8A CACNA1I SLC1A7	3.26e-05	171	71	6	GO:0015081
GeneOntologyMolecularFunction	calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	SLC8A2 SLC8A3	3.73e-05	3	71	2	GO:1905060
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	TRPM6 SLC12A6 SLC8A2 SLC8A3 SCN7A SCN8A HRH1 CACNA1I SLC1A7	3.86e-05	465	71	9	GO:0046873
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	GPR89B CLCN3 CLCN4 CLCN5 GPR89A CACNA1I	4.63e-05	182	71	6	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	GPR89B CLCN3 CLCN4 CLCN5 GPR89A CACNA1I	4.92e-05	184	71	6	GO:0022832
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	TRPM6 SLC12A6 SLC8A2 SLC8A3 SCN7A SCN8A HRH1 CACNA1I SLC1A7 ATP6V0A2	7.13e-05	627	71	10	GO:0022890
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN7A SCN8A CACNA1I	1.06e-04	26	71	3	GO:0005248
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPM6 SLC8A2 SLC8A3 HRH1 CACNA1I	2.02e-04	151	71	5	GO:0015085
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	ZDHHC2 ZDHHC23 CERS3 ELOVL5 ELOVL3 CERS1	2.02e-04	238	71	6	GO:0016747
GeneOntologyMolecularFunction	fatty acid elongase activity	ELOVL5 ELOVL3	2.59e-04	7	71	2	GO:0009922
GeneOntologyMolecularFunction	sphingosine N-acyltransferase activity	CERS3 CERS1	2.59e-04	7	71	2	GO:0050291
GeneOntologyMolecularFunction	volume-sensitive anion channel activity	CLCN3 LRRC8B	4.42e-04	9	71	2	GO:0005225
GeneOntologyMolecularFunction	calcium:sodium antiporter activity	SLC8A2 SLC8A3	5.51e-04	10	71	2	GO:0005432
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC12A6 SLC8A2 SLC8A3 ATP13A5 SLC1A7 ATP6V0A2	7.03e-04	301	71	6	GO:0022853
GeneOntologyMolecularFunction	sodium channel activity	SCN7A SCN8A CACNA1I	8.40e-04	52	71	3	GO:0005272
GeneOntologyMolecularFunction	calcium:monoatomic cation antiporter activity	SLC8A2 SLC8A3	9.48e-04	13	71	2	GO:0015368
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR6A2 CELSR1 OR4C6 OR6Q1 HRH1 OR1P1 SMO ADGRF4 PTH2R OR4D2	1.10e-03	884	71	10	GO:0004930
GeneOntologyMolecularFunction	acyltransferase activity	ZDHHC2 ZDHHC23 RNF148 CERS3 MARCHF6 ELOVL5 ELOVL3 CERS1 RNF145	1.65e-03	775	71	9	GO:0016746
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR6A2 CELSR1 OR4C6 OR6Q1 GLRA1 SCN7A HRH1 OR1P1 SMO ADGRF4 PTH2R OR4D2	2.75e-03	1353	71	12	GO:0004888
GeneOntologyMolecularFunction	glucosyltransferase activity	UGT8 ALG6	2.75e-03	22	71	2	GO:0046527
GeneOntologyMolecularFunction	phosphate transmembrane transporter activity	SLC37A3 XPR1	3.27e-03	24	71	2	GO:0005315
GeneOntologyMolecularFunction	protein-cysteine S-palmitoyltransferase activity	ZDHHC2 ZDHHC23	3.83e-03	26	71	2	GO:0019706
GeneOntologyMolecularFunction	protein-cysteine S-acyltransferase activity	ZDHHC2 ZDHHC23	3.83e-03	26	71	2	GO:0019707
GeneOntologyMolecularFunction	S-acyltransferase activity	ZDHHC2 ZDHHC23	5.08e-03	30	71	2	GO:0016417
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA12 ATP13A5 ATP6V0A2	6.91e-03	109	71	3	GO:0042626
GeneOntologyMolecularFunction	monoatomic cation channel activity	TRPM6 PIEZO2 SCN7A SCN8A CACNA1I	7.50e-03	343	71	5	GO:0005261
GeneOntologyMolecularFunction	palmitoyltransferase activity	ZDHHC2 ZDHHC23	7.66e-03	37	71	2	GO:0016409
GeneOntologyMolecularFunction	metal cation:monoatomic cation antiporter activity	SLC8A2 SLC8A3	1.02e-02	43	71	2	GO:0140828
GeneOntologyMolecularFunction	excitatory extracellular ligand-gated monoatomic ion channel activity	GLRA1 SLC1A7	1.02e-02	43	71	2	GO:0005231
GeneOntologyBiologicalProcess	monoatomic ion transport	TRPM6 SLC12A6 GPR89B SLC8A2 SLC8A3 PIEZO2 CLCN3 CLCN4 CLCN5 GLRA1 SCN7A SLC22A15 SCN8A HRH1 GPR89A CDH23 ATP13A5 CACNA1I LRRC8B MFSD4B SLC1A7 ATP6V0A2	5.87e-10	1374	71	22	GO:0006811
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	SLC12A6 GPR89B CLCN3 CLCN4 CLCN5 GLRA1 GPR89A LRRC8B SLC1A7	2.70e-09	153	71	9	GO:0098656
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	TRPM6 SLC12A6 GPR89B SLC8A2 SLC8A3 PIEZO2 CLCN3 CLCN4 CLCN5 GLRA1 SCN7A SCN8A HRH1 GPR89A ATP13A5 CACNA1I LRRC8B SLC1A7 ATP6V0A2	4.28e-09	1115	71	19	GO:0034220
GeneOntologyBiologicalProcess	monoatomic anion transport	SLC12A6 GPR89B CLCN3 CLCN4 CLCN5 GLRA1 GPR89A LRRC8B SLC1A7	1.30e-08	183	71	9	GO:0006820
GeneOntologyBiologicalProcess	inorganic anion transmembrane transport	SLC12A6 CLCN3 SLC37A3 CLCN4 CLCN5 GLRA1 SLC1A7 XPR1	1.94e-08	134	71	8	GO:0098661
GeneOntologyBiologicalProcess	sphingolipid metabolic process	ACER1 PLPP3 ABCA12 CERS3 ELOVL5 UGT8 ELOVL3 CERS1	1.61e-07	176	71	8	GO:0006665
GeneOntologyBiologicalProcess	inorganic anion transport	SLC12A6 CLCN3 SLC37A3 CLCN4 CLCN5 GLRA1 SLC1A7 XPR1	1.92e-07	180	71	8	GO:0015698
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	TRPM6 SLC12A6 SLC8A2 SLC8A3 CLCN3 SLC37A3 CLCN4 CLCN5 GLRA1 SCN7A SCN8A HRH1 CACNA1I SLC1A7 ATP6V0A2 XPR1	2.69e-07	1017	71	16	GO:0098660
GeneOntologyBiologicalProcess	membrane lipid metabolic process	ACER1 PLPP3 ABCA12 CERS3 ELOVL5 UGT8 ELOVL3 CERS1	1.19e-06	229	71	8	GO:0006643
GeneOntologyBiologicalProcess	chloride transmembrane transport	SLC12A6 CLCN3 CLCN4 CLCN5 GLRA1 SLC1A7	2.41e-06	112	71	6	GO:1902476
GeneOntologyBiologicalProcess	ceramide metabolic process	ACER1 PLPP3 ABCA12 CERS3 UGT8 CERS1	2.54e-06	113	71	6	GO:0006672
GeneOntologyBiologicalProcess	sphingolipid biosynthetic process	ACER1 CERS3 ELOVL5 UGT8 ELOVL3 CERS1	3.10e-06	117	71	6	GO:0030148
GeneOntologyBiologicalProcess	alpha-linolenic acid metabolic process	FADS1 ELOVL5 ELOVL3	4.61e-06	10	71	3	GO:0036109
GeneOntologyBiologicalProcess	chloride transport	SLC12A6 CLCN3 CLCN4 CLCN5 GLRA1 SLC1A7	5.23e-06	128	71	6	GO:0006821
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	SLC12A6 GPR89B SLC8A2 SLC8A3 CLCN3 ABCA12 SV2B SCN7A GPR89A CDH23 ATP13A5 ATP6V0A2 XPR1	7.00e-06	866	71	13	GO:0055082
GeneOntologyBiologicalProcess	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	VANGL2 CELSR1	1.17e-05	2	71	2	GO:0060488
GeneOntologyBiologicalProcess	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	VANGL2 CELSR1	1.17e-05	2	71	2	GO:0060489
GeneOntologyBiologicalProcess	lateral sprouting involved in lung morphogenesis	VANGL2 CELSR1	1.17e-05	2	71	2	GO:0060490
GeneOntologyBiologicalProcess	membrane lipid biosynthetic process	ACER1 CERS3 ELOVL5 UGT8 ELOVL3 CERS1	1.68e-05	157	71	6	GO:0046467
GeneOntologyBiologicalProcess	cellular homeostasis	SLC12A6 GPR89B SLC8A2 SLC8A3 CLCN3 ABCA12 SV2B SCN7A GPR89A CDH23 ATP13A5 ATP6V0A2 XPR1	2.63e-05	981	71	13	GO:0019725
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	SLC12A6 GPR89B SLC8A2 SLC8A3 CLCN3 SV2B SCN7A GPR89A CDH23 ATP13A5 ATP6V0A2	2.72e-05	705	71	11	GO:0055080
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	SLC12A6 GPR89B SLC8A2 SLC8A3 CLCN3 SV2B SCN7A GPR89A CDH23 ATP13A5 ATP6V0A2	3.18e-05	717	71	11	GO:0050801
GeneOntologyBiologicalProcess	monoatomic cation transport	TRPM6 SLC12A6 SLC8A2 SLC8A3 PIEZO2 CLCN3 SCN7A SCN8A HRH1 CDH23 ATP13A5 CACNA1I MFSD4B ATP6V0A2	3.37e-05	1157	71	14	GO:0006812
GeneOntologyBiologicalProcess	dichotomous subdivision of terminal units involved in lung branching	VANGL2 CELSR1	3.50e-05	3	71	2	GO:0060448
GeneOntologyBiologicalProcess	skin development	VANGL2 GPR89B CELSR1 ACER1 ABCA12 CERS3 GPR89A SMO	4.18e-05	373	71	8	GO:0043588
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	GPR89B SLC8A2 SLC8A3 CLCN3 SV2B SCN7A GPR89A CDH23 ATP13A5 ATP6V0A2	4.39e-05	611	71	10	GO:0030003
GeneOntologyBiologicalProcess	intracellular pH reduction	GPR89B CLCN3 GPR89A ATP6V0A2	4.75e-05	58	71	4	GO:0051452
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	GPR89B SLC8A2 SLC8A3 CLCN3 SV2B SCN7A GPR89A CDH23 ATP13A5 ATP6V0A2	5.10e-05	622	71	10	GO:0006873
GeneOntologyBiologicalProcess	amide metabolic process	ACER1 PLPP3 ABCA12 CERS3 ELOVL5 PCSK7 UGT8 ELOVL3 CERS1	6.24e-05	511	71	9	GO:0043603
GeneOntologyBiologicalProcess	linoleic acid metabolic process	FADS1 ELOVL5 ELOVL3	6.59e-05	23	71	3	GO:0043651
GeneOntologyBiologicalProcess	establishment of body hair planar orientation	VANGL2 CELSR1	6.98e-05	4	71	2	GO:0048105
GeneOntologyBiologicalProcess	establishment of body hair or bristle planar orientation	VANGL2 CELSR1	6.98e-05	4	71	2	GO:0048104
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	TRPM6 SLC12A6 SLC8A2 SLC8A3 PIEZO2 CLCN3 SCN7A SCN8A HRH1 ATP13A5 CACNA1I ATP6V0A2	8.16e-05	942	71	12	GO:0098655
GeneOntologyBiologicalProcess	fatty acid elongation, polyunsaturated fatty acid	ELOVL5 ELOVL3	2.43e-04	7	71	2	GO:0034626
GeneOntologyBiologicalProcess	fatty acid elongation, monounsaturated fatty acid	ELOVL5 ELOVL3	2.43e-04	7	71	2	GO:0034625
GeneOntologyBiologicalProcess	fatty acid elongation, unsaturated fatty acid	ELOVL5 ELOVL3	2.43e-04	7	71	2	GO:0019368
GeneOntologyBiologicalProcess	inorganic ion homeostasis	SLC12A6 SLC8A2 SLC8A3 SV2B SCN7A CDH23 ATP13A5 ATP6V0A2 XPR1	2.74e-04	622	71	9	GO:0098771
GeneOntologyBiologicalProcess	chemical homeostasis	SLC12A6 GPR89B SLC8A2 SLC8A3 CLCN3 ABCA12 SV2B SCN7A GPR89A CDH23 ATP13A5 ATP6V0A2 XPR1	2.99e-04	1249	71	13	GO:0048878
GeneOntologyBiologicalProcess	regulation of intracellular pH	GPR89B CLCN3 GPR89A ATP6V0A2	3.11e-04	94	71	4	GO:0051453
GeneOntologyBiologicalProcess	amide biosynthetic process	CERS3 ELOVL5 UGT8 ELOVL3 CERS1	3.18e-04	172	71	5	GO:0043604
GeneOntologyBiologicalProcess	fatty acid elongation, saturated fatty acid	ELOVL5 ELOVL3	3.23e-04	8	71	2	GO:0019367
GeneOntologyBiologicalProcess	calcium ion import	SLC8A2 SLC8A3 HRH1 CACNA1I	3.65e-04	98	71	4	GO:0070509
GeneOntologyBiologicalProcess	sodium ion transport	SLC8A2 SLC8A3 SCN7A SCN8A CACNA1I MFSD4B	3.69e-04	275	71	6	GO:0006814
GeneOntologyBiologicalProcess	calcium ion transport into cytosol	SLC8A2 SLC8A3 CACNA1I	4.08e-04	42	71	3	GO:0060402
GeneOntologyBiologicalProcess	regulation of cellular pH	GPR89B CLCN3 GPR89A ATP6V0A2	4.09e-04	101	71	4	GO:0030641
GeneOntologyBiologicalProcess	calcium ion import across plasma membrane	SLC8A2 SLC8A3 CACNA1I	6.05e-04	48	71	3	GO:0098703
GeneOntologyBiologicalProcess	calcium ion import into cytosol	SLC8A2 SLC8A3 CACNA1I	6.05e-04	48	71	3	GO:1902656
GeneOntologyBiologicalProcess	dichotomous subdivision of an epithelial terminal unit	VANGL2 CELSR1	6.30e-04	11	71	2	GO:0060600
GeneOntologyBiologicalProcess	action potential	SLC8A2 GLRA1 SCN7A SCN8A CACNA1I	6.46e-04	201	71	5	GO:0001508
GeneOntologyBiologicalProcess	regulation of membrane potential	SLC8A2 SLC8A3 PIEZO2 GLRA1 SCN7A SCN8A CACNA1I SLC1A7	6.57e-04	559	71	8	GO:0042391
GeneOntologyBiologicalProcess	adult locomotory behavior	CLCN3 GLRA1 SCN8A CDH23	6.90e-04	116	71	4	GO:0008344
GeneOntologyBiologicalProcess	calcium ion export across plasma membrane	SLC8A2 SLC8A3	7.54e-04	12	71	2	GO:1990034
GeneOntologyBiologicalProcess	righting reflex	GLRA1 CDH23	7.54e-04	12	71	2	GO:0060013
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SLC8A2 SLC8A3 SCN7A SCN8A CACNA1I	7.54e-04	208	71	5	GO:0035725
GeneOntologyBiologicalProcess	regulation of pH	GPR89B CLCN3 GPR89A ATP6V0A2	7.84e-04	120	71	4	GO:0006885
GeneOntologyBiologicalProcess	very long-chain fatty acid biosynthetic process	ELOVL5 ELOVL3	8.89e-04	13	71	2	GO:0042761
GeneOntologyBiologicalProcess	lateral sprouting from an epithelium	VANGL2 CELSR1	8.89e-04	13	71	2	GO:0060601
GeneOntologyBiologicalProcess	unsaturated fatty acid biosynthetic process	FADS1 ELOVL5 ELOVL3	9.51e-04	56	71	3	GO:0006636
GeneOntologyBiologicalProcess	excitatory postsynaptic potential	SLC8A2 SLC8A3 GLRA1 SLC1A7	1.06e-03	130	71	4	GO:0060079
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	TRPM6 SLC12A6 SLC8A2 SLC8A3 CLCN3 SCN7A SCN8A HRH1 CACNA1I ATP6V0A2	1.18e-03	922	71	10	GO:0098662
GeneOntologyBiologicalProcess	import across plasma membrane	SLC12A6 SLC8A2 SLC8A3 CACNA1I LRRC8B	1.18e-03	230	71	5	GO:0098739
GeneOntologyBiologicalProcess	fatty acid elongation	ELOVL5 ELOVL3	1.19e-03	15	71	2	GO:0030497
GeneOntologyBiologicalProcess	regulation of establishment of planar polarity involved in neural tube closure	VANGL2 CELSR1	1.19e-03	15	71	2	GO:0090178
GeneOntologyBiologicalProcess	phosphate ion transmembrane transport	SLC37A3 XPR1	1.19e-03	15	71	2	GO:0035435
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	ZDHHC2 SLC12A6 SLC8A2 SLC8A3 MCTP1 CLCN3 SV2B GLRA1 HRH1 SLC1A7	1.27e-03	931	71	10	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	ZDHHC2 SLC12A6 SLC8A2 SLC8A3 MCTP1 CLCN3 SV2B GLRA1 HRH1 SLC1A7	1.27e-03	931	71	10	GO:0007268
GeneOntologyBiologicalProcess	neuronal action potential	GLRA1 SCN8A CACNA1I	1.34e-03	63	71	3	GO:0019228
GeneOntologyBiologicalProcess	trans-synaptic signaling	ZDHHC2 SLC12A6 SLC8A2 SLC8A3 MCTP1 CLCN3 SV2B GLRA1 HRH1 SLC1A7	1.35e-03	939	71	10	GO:0099537
GeneOntologyBiologicalProcess	establishment of planar polarity involved in neural tube closure	VANGL2 CELSR1	1.36e-03	16	71	2	GO:0090177
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	SLC12A6 SLC8A2 SLC8A3 CACNA1I	1.46e-03	142	71	4	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	SLC12A6 SLC8A2 SLC8A3 CACNA1I	1.46e-03	142	71	4	GO:0098659
GeneOntologyBiologicalProcess	apical protein localization	VANGL2 CELSR1	1.54e-03	17	71	2	GO:0045176
GeneOntologyBiologicalProcess	chemical synaptic transmission, postsynaptic	SLC8A2 SLC8A3 GLRA1 SLC1A7	1.66e-03	147	71	4	GO:0099565
GeneOntologyBiologicalProcess	establishment of planar polarity of embryonic epithelium	VANGL2 CELSR1	1.72e-03	18	71	2	GO:0042249
GeneOntologyBiologicalProcess	synaptic signaling	ZDHHC2 SLC12A6 SLC8A2 SLC8A3 MCTP1 CLCN3 SV2B GLRA1 HRH1 SLC1A7	1.80e-03	976	71	10	GO:0099536
GeneOntologyBiologicalProcess	regulation of establishment of planar polarity	VANGL2 CELSR1	1.92e-03	19	71	2	GO:0090175
GeneOntologyBiologicalProcess	long-chain fatty-acyl-CoA biosynthetic process	ELOVL5 ELOVL3	1.92e-03	19	71	2	GO:0035338
GeneOntologyBiologicalProcess	ceramide biosynthetic process	CERS3 UGT8 CERS1	2.05e-03	73	71	3	GO:0046513
GeneOntologyBiologicalProcess	metal ion transport	TRPM6 SLC12A6 SLC8A2 SLC8A3 SCN7A SCN8A HRH1 CDH23 CACNA1I MFSD4B	2.15e-03	1000	71	10	GO:0030001
GeneOntologyBiologicalProcess	sphingosine metabolic process	ACER1 PLPP3	2.35e-03	21	71	2	GO:0006670
GeneOntologyBiologicalProcess	skin epidermis development	VANGL2 CELSR1 ABCA12 SMO	2.59e-03	166	71	4	GO:0098773
GeneOntologyBiologicalProcess	sphingoid metabolic process	ACER1 PLPP3	2.82e-03	23	71	2	GO:0046519
GeneOntologyBiologicalProcess	regulation of neuronal synaptic plasticity	ZDHHC2 SLC8A2 MCTP1	2.95e-03	83	71	3	GO:0048168
GeneOntologyBiologicalProcess	locomotory behavior	CELSR1 CLCN3 GLRA1 SCN8A CDH23	2.97e-03	284	71	5	GO:0007626
GeneOntologyBiologicalProcess	regulation of cytosolic calcium ion concentration	SLC8A2 SV2B CDH23	3.05e-03	84	71	3	GO:0051480
GeneOntologyBiologicalProcess	neuron cellular homeostasis	SLC8A2 CLCN3 SV2B	3.05e-03	84	71	3	GO:0070050
GeneOntologyBiologicalProcess	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	ZDHHC2 ZDHHC23	3.07e-03	24	71	2	GO:0018231
GeneOntologyBiologicalProcess	peptidyl-L-cysteine S-palmitoylation	ZDHHC2 ZDHHC23	3.07e-03	24	71	2	GO:0018230
GeneOntologyBiologicalProcess	sulfur compound biosynthetic process	VANGL2 ELOVL5 ELOVL3 HS3ST3B1	3.32e-03	178	71	4	GO:0044272
GeneOntologyBiologicalProcess	regulation of synaptic plasticity	ZDHHC2 SLC8A2 SLC8A3 MCTP1 HRH1	3.39e-03	293	71	5	GO:0048167
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane potential	SLC8A2 SLC8A3 GLRA1 SLC1A7	3.46e-03	180	71	4	GO:0060078
GeneOntologyCellularComponent	endoplasmic reticulum membrane	ZDHHC2 TEX261 SLC8A3 FADS1 ACER1 MCTP1 SLC37A3 CLCN4 PLPP3 BET1 DIPK1A KTN1 CERS3 MARCHF6 ELOVL5 UGT2B10 UGT8 ELOVL3 LRRC8B CERS1 RNF145 ALG6	7.67e-11	1293	69	22	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	ZDHHC2 TEX261 SLC8A3 FADS1 ACER1 MCTP1 SLC37A3 CLCN4 PLPP3 BET1 DIPK1A KTN1 CERS3 MARCHF6 ELOVL5 UGT2B10 UGT8 ELOVL3 LRRC8B CERS1 RNF145 ALG6	8.38e-11	1299	69	22	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	ZDHHC2 TEX261 SLC8A3 FADS1 ACER1 MCTP1 SLC37A3 CLCN4 PLPP3 BET1 DIPK1A KTN1 CERS3 MARCHF6 ELOVL5 UGT2B10 UGT8 ELOVL3 LRRC8B CERS1 RNF145 ALG6	1.26e-10	1327	69	22	GO:0042175
GeneOntologyCellularComponent	Golgi membrane	ZDHHC2 GPR89B TEX261 CLCN3 CLCN5 ZDHHC23 PLPP3 ABCA12 BET1 GPR89A PCSK7 HS3ST3B1 ATP6V0A2	5.71e-07	721	69	13	GO:0000139
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	ZDHHC2 GPR89B MCTP1 CLCN3 CLCN4 CLCN5 ABCA12 SV2B SCAMP1 GPR89A ATP13A5 SMO SLC35G2 TMEM225 ATP6V0A2	1.86e-05	1307	69	15	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	ZDHHC2 GPR89B MCTP1 CLCN3 CLCN4 CLCN5 ABCA12 SV2B SCAMP1 GPR89A ATP13A5 SMO SLC35G2 TMEM225 ATP6V0A2	2.18e-05	1325	69	15	GO:0012506
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN7A SCN8A CACNA1I	2.26e-05	17	69	3	GO:0001518
GeneOntologyCellularComponent	presynapse	SLC8A2 SLC8A3 MCTP1 CLCN3 CLCN4 CLCN5 SV2B SCAMP1 GLRA1 SCN8A SLC35G2 SLC1A7	2.96e-05	886	69	12	GO:0098793
GeneOntologyCellularComponent	transport vesicle	MCTP1 CLCN3 CLCN4 CLCN5 ABCA12 BET1 SV2B SCAMP1 SLC35G2	5.05e-05	519	69	9	GO:0030133
GeneOntologyCellularComponent	synaptic vesicle	MCTP1 CLCN3 CLCN4 CLCN5 SV2B SCAMP1 SLC35G2	5.89e-05	300	69	7	GO:0008021
GeneOntologyCellularComponent	exocytic vesicle	MCTP1 CLCN3 CLCN4 CLCN5 SV2B SCAMP1 SLC35G2	8.83e-05	320	69	7	GO:0070382
GeneOntologyCellularComponent	sodium channel complex	SCN7A SCN8A CACNA1I	1.18e-04	29	69	3	GO:0034706
GeneOntologyCellularComponent	monoatomic ion channel complex	GPR89B GLRA1 SCN7A SCN8A GPR89A CACNA1I LRRC8B	2.46e-04	378	69	7	GO:0034702
GeneOntologyCellularComponent	exocytic vesicle membrane	MCTP1 CLCN3 SV2B SCAMP1 SLC35G2	3.14e-04	179	69	5	GO:0099501
GeneOntologyCellularComponent	synaptic vesicle membrane	MCTP1 CLCN3 SV2B SCAMP1 SLC35G2	3.14e-04	179	69	5	GO:0030672
GeneOntologyCellularComponent	transmembrane transporter complex	GPR89B GLRA1 SCN7A SCN8A GPR89A CACNA1I LRRC8B ATP6V0A2	3.19e-04	523	69	8	GO:1902495
GeneOntologyCellularComponent	postsynaptic membrane	VANGL2 SLC8A2 SLC8A3 CLCN3 GLRA1 SCN8A SLC1A7	3.73e-04	405	69	7	GO:0045211
GeneOntologyCellularComponent	transport vesicle membrane	MCTP1 CLCN3 ABCA12 SV2B SCAMP1 SLC35G2	4.12e-04	293	69	6	GO:0030658
GeneOntologyCellularComponent	transporter complex	GPR89B GLRA1 SCN7A SCN8A GPR89A CACNA1I LRRC8B ATP6V0A2	4.46e-04	550	69	8	GO:1990351
GeneOntologyCellularComponent	recycling endosome membrane	ZDHHC2 CLCN3 CLCN4 SCAMP1	5.16e-04	112	69	4	GO:0055038
GeneOntologyCellularComponent	axon terminus	SLC8A2 SLC8A3 CLCN3 GLRA1 SLC1A7	6.51e-04	210	69	5	GO:0043679
GeneOntologyCellularComponent	recycling endosome	ZDHHC2 MCTP1 CLCN3 CLCN4 SCAMP1	8.36e-04	222	69	5	GO:0055037
GeneOntologyCellularComponent	neuron projection terminus	SLC8A2 SLC8A3 CLCN3 GLRA1 SLC1A7	1.04e-03	233	69	5	GO:0044306
GeneOntologyCellularComponent	synaptic membrane	VANGL2 SLC8A2 SLC8A3 CLCN3 GLRA1 SCN8A SLC1A7	3.06e-03	583	69	7	GO:0097060
GeneOntologyCellularComponent	distal axon	SLC8A2 SLC8A3 CLCN3 GLRA1 SMO SLC1A7	3.11e-03	435	69	6	GO:0150034
GeneOntologyCellularComponent	apical part of cell	VANGL2 TRPM6 SLC12A6 CLCN3 CLCN5 CDH23 MFSD4B	3.33e-03	592	69	7	GO:0045177
GeneOntologyCellularComponent	membrane protein complex	GPR89B BET1 GLRA1 MARCHF6 SCN7A SCN8A GPR89A CDH23 CACNA1I LRRC8B ATP6V0A2 TSPAN33	3.40e-03	1498	69	12	GO:0098796
GeneOntologyCellularComponent	Golgi apparatus subcompartment	GPR89B PLPP3 BET1 SCAMP1 GPR89A PCSK7	3.41e-03	443	69	6	GO:0098791
GeneOntologyCellularComponent	endosome membrane	ZDHHC2 CLCN3 CLCN4 CLCN5 SCAMP1 ATP13A5 ATP6V0A2	3.66e-03	602	69	7	GO:0010008
GeneOntologyCellularComponent	inhibitory synapse	CLCN3 GLRA1	4.69e-03	31	69	2	GO:0060077
GeneOntologyCellularComponent	endosome	ZDHHC2 MCTP1 CLCN3 CLCN4 CLCN5 RNF148 SCAMP1 ATP13A5 SMO ATP6V0A2	4.78e-03	1167	69	10	GO:0005768
GeneOntologyCellularComponent	late endosome	CLCN3 CLCN4 RNF148 ATP13A5 SMO	5.85e-03	348	69	5	GO:0005770
GeneOntologyCellularComponent	postsynaptic specialization	VANGL2 ZDHHC2 SLC8A2 SLC8A3 GLRA1 SCN8A	6.28e-03	503	69	6	GO:0099572
GeneOntologyCellularComponent	dendrite	SLC8A2 SLC8A3 GLRA1 SCN8A ELOVL5 TMEM185A HRH1 SMO	7.14e-03	858	69	8	GO:0030425
GeneOntologyCellularComponent	dendritic tree	SLC8A2 SLC8A3 GLRA1 SCN8A ELOVL5 TMEM185A HRH1 SMO	7.24e-03	860	69	8	GO:0097447
GeneOntologyCellularComponent	secretory vesicle	MCTP1 CLCN3 CLCN4 CLCN5 ABCA12 SV2B SCAMP1 SLC35G2 TMEM225 ATP6V0A2	7.50e-03	1246	69	10	GO:0099503
MousePheno	abnormal stationary movement	VANGL2 CELSR1 GLRA1 SCN8A UGT8 CDH23	1.49e-05	147	51	6	MP:0001388
MousePheno	abnormal head movements	VANGL2 CELSR1 SCN8A UGT8 CDH23	3.54e-05	103	51	5	MP:0000436
MousePheno	abnormal skin development	ACER1 ABCA12 CERS3	4.25e-05	19	51	3	MP:0003941
MousePheno	head shaking	VANGL2 CELSR1 CDH23	6.71e-05	22	51	3	MP:0002730
MousePheno	dilated terminal bronchiole tube	VANGL2 CELSR1	7.79e-05	4	51	2	MP:0006026
MousePheno	impaired skin barrier function	ACER1 ABCA12 CERS3 ELOVL3	8.50e-05	64	51	4	MP:0002796
MousePheno	abnormal orientation of outer hair cell stereociliary bundles	VANGL2 CELSR1 CDH23	8.77e-05	24	51	3	MP:0004491
MousePheno	abnormal neural plate morphology	VANGL2 CELSR1 SMO	1.12e-04	26	51	3	MP:0005657
MousePheno	abnormal epidermis stratum granulosum morphology	ACER1 ABCA12 CERS3 ELOVL3	1.21e-04	70	51	4	MP:0001239
MousePheno	stereotypic behavior	VANGL2 CELSR1 MCTP1 CLCN3 SCN8A CDH23	1.22e-04	214	51	6	MP:0001408
MousePheno	impaired stratum corneum desquamation	ABCA12 CERS3	1.30e-04	5	51	2	MP:0009597
MousePheno	impaired branching involved in terminal bronchiole morphogenesis	VANGL2 CELSR1	1.30e-04	5	51	2	MP:0011032
MousePheno	abnormal eye electrophysiology	CLCN3 SV2B GLRA1 SCN8A CDH23 SLC1A7	1.72e-04	228	51	6	MP:0005551
MousePheno	abnormal outer hair cell kinocilium location or orientation	CELSR1 CDH23	1.94e-04	6	51	2	MP:0030961
MousePheno	abnormal keratinocyte physiology	ACER1 ABCA12 CERS3 MAP3K6	2.13e-04	81	51	4	MP:0003453
MousePheno	small lung lobe	VANGL2 CELSR1	2.71e-04	7	51	2	MP:0010976
MousePheno	abnormal branching involved in terminal bronchiole morphogenesis	VANGL2 CELSR1	2.71e-04	7	51	2	MP:0011031
MousePheno	abnormal cochlear outer hair cell morphology	VANGL2 SLC12A6 CELSR1 MCTP1 CDH23	2.75e-04	159	51	5	MP:0004399
MousePheno	head tossing	CELSR1 SCN8A CDH23	2.76e-04	35	51	3	MP:0005307
MousePheno	abnormal orientation of cochlear hair cell stereociliary bundles	VANGL2 CELSR1 CDH23	2.76e-04	35	51	3	MP:0004522
MousePheno	ataxia	SLC12A6 GLRA1 SCN8A UGT8 CDH23 CERS1	3.94e-04	266	51	6	MP:0001393
MousePheno	muscle hypertonia	SLC12A6 GLRA1	4.62e-04	9	51	2	MP:0004143
MousePheno	abnormal terminal bronchiole morphology	VANGL2 CELSR1	5.76e-04	10	51	2	MP:0002268
MousePheno	peripheral nervous system degeneration	SLC12A6 SCN8A	5.76e-04	10	51	2	MP:0000958
MousePheno	abnormal outer hair cell kinocilium morphology	CELSR1 CDH23	5.76e-04	10	51	2	MP:0011062
MousePheno	small scala media	VANGL2 MCTP1	5.76e-04	10	51	2	MP:0008308
MousePheno	abnormal skin physiology	ZDHHC2 ACER1 ABCA12 CERS3 ELOVL3 MAP3K6	6.00e-04	288	51	6	MP:0005501
MousePheno	abnormal sebaceous lipid secretion	ACER1 ELOVL3	7.03e-04	11	51	2	MP:0002992
MousePheno	abnormal cochlear hair cell morphology	VANGL2 SLC12A6 CELSR1 MCTP1 CDH23	8.21e-04	202	51	5	MP:0002622
MousePheno	abnormal orientation of inner hair cell stereociliary bundles	VANGL2 CDH23	8.41e-04	12	51	2	MP:0004492
MousePheno	abnormal cochlear sensory epithelium morphology	VANGL2 SLC12A6 CELSR1 MCTP1 CDH23	9.16e-04	207	51	5	MP:0003308
MousePheno	abnormal organ of Corti morphology	VANGL2 SLC12A6 CELSR1 MCTP1 CDH23	9.57e-04	209	51	5	MP:0000042
MousePheno	abnormal epidermal lamellar body morphology	ABCA12 CERS3	9.92e-04	13	51	2	MP:0009608
MousePheno	abnormal hair cell morphology	VANGL2 SLC12A6 CELSR1 MCTP1 CDH23	1.06e-03	214	51	5	MP:0000045
MousePheno	abnormal cochlear inner hair cell morphology	VANGL2 SLC12A6 MCTP1 CDH23	1.07e-03	124	51	4	MP:0004393
MousePheno	abnormal locomotor circadian rhythm	HRH1 PTH2R	1.15e-03	14	51	2	MP:0020477
MousePheno	abnormal nervous system electrophysiology	SLC12A6 GLRA1 SCN8A UGT8 CDH23 CACNA1I	1.20e-03	329	51	6	MP:0002272
MousePheno	abnormal neuron number	VANGL2 CLCN3 GLRA1 SCN8A CDH23 SMO CERS1	1.26e-03	456	51	7	MP:0008946
MousePheno	abnormal nerve conduction	SLC12A6 SCN8A UGT8	1.29e-03	59	51	3	MP:0005403
Domain	Cl-channel_core	CLCN3 CLCN4 CLCN5	3.99e-06	9	69	3	IPR014743
Domain	-	CLCN3 CLCN4 CLCN5	3.99e-06	9	69	3	1.10.3080.10
Domain	Voltage_CLC	CLCN3 CLCN4 CLCN5	3.99e-06	9	69	3	PF00654
Domain	Cl-channel_volt-gated	CLCN3 CLCN4 CLCN5	3.99e-06	9	69	3	IPR001807
Domain	CBS	CLCN3 CLCN4 CLCN5	2.61e-05	16	69	3	SM00116
Domain	Na_Ca_Ex	SLC8A2 SLC8A3	4.03e-05	3	69	2	IPR004836
Domain	Na_Ca_ex_C	SLC8A2 SLC8A3	4.03e-05	3	69	2	PF16494
Domain	Na_Ca_Ex_C-exten	SLC8A2 SLC8A3	4.03e-05	3	69	2	IPR032452
Domain	CBS_dom	CLCN3 CLCN4 CLCN5	5.26e-05	20	69	3	IPR000644
Domain	CBS	CLCN3 CLCN4 CLCN5	5.26e-05	20	69	3	PF00571
Domain	CBS	CLCN3 CLCN4 CLCN5	5.26e-05	20	69	3	PS51371
Domain	GPCR_2-like	CELSR1 SMO ADGRF4 PTH2R	7.12e-05	60	69	4	IPR017981
Domain	GPCR_2_secretin-like	CELSR1 SMO ADGRF4 PTH2R	7.12e-05	60	69	4	IPR000832
Domain	G_PROTEIN_RECEP_F2_4	CELSR1 SMO ADGRF4 PTH2R	7.60e-05	61	69	4	PS50261
Domain	TM_Fragile-X-F-assoc	TMEM185B TMEM185A	8.03e-05	4	69	2	IPR019396
Domain	Tmemb_185A	TMEM185B TMEM185A	8.03e-05	4	69	2	PF10269
Domain	Lag1/Lac1	CERS3 CERS1	2.00e-04	6	69	2	IPR016439
Domain	ELO	ELOVL5 ELOVL3	2.79e-04	7	69	2	PF01151
Domain	ELO	ELOVL5 ELOVL3	2.79e-04	7	69	2	PS01188
Domain	ELO_fam	ELOVL5 ELOVL3	2.79e-04	7	69	2	IPR002076
Domain	Calx_beta	SLC8A2 SLC8A3	3.71e-04	8	69	2	SM00237
Domain	G_PROTEIN_RECEP_F2_1	CELSR1 ADGRF4 PTH2R	4.32e-04	40	69	3	PS00649
Domain	G_PROTEIN_RECEP_F2_3	CELSR1 ADGRF4 PTH2R	4.32e-04	40	69	3	PS50227
Domain	GPCR_2_extracellular_dom	CELSR1 ADGRF4 PTH2R	4.32e-04	40	69	3	IPR001879
Domain	Calx_beta	SLC8A2 SLC8A3	4.76e-04	9	69	2	IPR003644
Domain	NaCa_Exmemb	SLC8A2 SLC8A3	4.76e-04	9	69	2	IPR004837
Domain	Na_Ca_ex	SLC8A2 SLC8A3	4.76e-04	9	69	2	PF01699
Domain	Calx-beta	SLC8A2 SLC8A3	4.76e-04	9	69	2	PF03160
Domain	Na_channel_asu	SCN7A SCN8A	5.94e-04	10	69	2	IPR001696
Domain	Na_trans_assoc	SCN7A SCN8A	5.94e-04	10	69	2	IPR010526
Domain	Na_trans_assoc	SCN7A SCN8A	5.94e-04	10	69	2	PF06512
Domain	G_PROTEIN_RECEP_F2_2	CELSR1 ADGRF4 PTH2R	8.35e-04	50	69	3	PS00650
Domain	7tm_2	CELSR1 ADGRF4 PTH2R	8.35e-04	50	69	3	PF00002
Domain	Ion_trans_dom	TRPM6 SCN7A SCN8A CACNA1I	8.39e-04	114	69	4	IPR005821
Domain	Ion_trans	TRPM6 SCN7A SCN8A CACNA1I	8.39e-04	114	69	4	PF00520
Domain	Channel_four-helix_dom	SCN7A SCN8A CACNA1I	1.22e-03	57	69	3	IPR027359
Domain	-	SCN7A SCN8A CACNA1I	1.22e-03	57	69	3	1.20.120.350
Domain	MFS_dom	SLC37A3 SV2B SLC22A15 MFSD4B	1.53e-03	134	69	4	IPR020846
Domain	TLC	CERS3 CERS1	1.56e-03	16	69	2	PS50922
Domain	TRAM_LAG1_CLN8	CERS3 CERS1	1.56e-03	16	69	2	PF03798
Domain	TLC-dom	CERS3 CERS1	1.56e-03	16	69	2	IPR006634
Domain	TLC	CERS3 CERS1	1.56e-03	16	69	2	SM00724
Domain	Znf_RING-CH	MARCHF6 RNF145	1.76e-03	17	69	2	IPR011016
Domain	RINGv	MARCHF6 RNF145	1.76e-03	17	69	2	SM00744
Domain	UDPGT	UGT2B10 UGT8	2.70e-03	21	69	2	PS00375
Domain	UDPGT	UGT2B10 UGT8	2.70e-03	21	69	2	PF00201
Domain	UDP_glucos_trans	UGT2B10 UGT8	2.70e-03	21	69	2	IPR002213
Domain	MFS	SLC37A3 SV2B MFSD4B	2.90e-03	77	69	3	IPR011701
Domain	MFS_1	SLC37A3 SV2B MFSD4B	2.90e-03	77	69	3	PF07690
Domain	zf-DHHC	ZDHHC2 ZDHHC23	3.24e-03	23	69	2	PF01529
Domain	DHHC	ZDHHC2 ZDHHC23	3.82e-03	25	69	2	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC2 ZDHHC23	3.82e-03	25	69	2	IPR001594
Domain	HormR	CELSR1 PTH2R	3.82e-03	25	69	2	SM00008
Domain	HRM	CELSR1 PTH2R	4.78e-03	28	69	2	PF02793
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	TRPM6 SLC12A6 SLC8A2 SLC8A3 CLCN3 CLCN4 CLCN5 ABCA12 SLC22A15 ATP13A5 LRRC8B MFSD4B SLC1A7 ATP6V0A2	4.57e-07	736	54	14	M27287
Pathway	WP_GPCRS_OTHER	OR6A2 CELSR1 OR1P1 SMO ADGRF4 PTH2R	1.69e-06	96	54	6	MM15939
Pathway	WP_SPHINGOLIPID_METABOLISM_OVERVIEW	PLPP3 CERS3 UGT8 CERS1	2.29e-06	25	54	4	MM15931
Pathway	WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY	PLPP3 CERS3 UGT8 CERS1	2.70e-06	26	54	4	M39784
Pathway	WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY	PLPP3 CERS3 UGT8 CERS1	2.70e-06	26	54	4	MM15892
Pathway	REACTOME_LINOLEIC_ACID_LA_METABOLISM	FADS1 ELOVL5 ELOVL3	2.94e-06	8	54	3	MM14822
Pathway	REACTOME_LINOLEIC_ACID_LA_METABOLISM	FADS1 ELOVL5 ELOVL3	2.94e-06	8	54	3	M27115
Pathway	WP_SPHINGOLIPID_METABOLISM_OVERVIEW	PLPP3 CERS3 UGT8 CERS1	3.16e-06	27	54	4	M39863
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	TRPM6 SLC12A6 SLC8A2 SLC8A3 CLCN4 CLCN5 ABCA12 SLC22A15 ATP13A5 LRRC8B SLC1A7 ATP6V0A2	7.75e-06	681	54	12	MM14985
Pathway	WP_ELONGATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS	FADS1 ELOVL5 ELOVL3	1.14e-05	12	54	3	MM17077
Pathway	REACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM	FADS1 ELOVL5 ELOVL3	1.48e-05	13	54	3	MM14821
Pathway	REACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM	FADS1 ELOVL5 ELOVL3	1.48e-05	13	54	3	M27114
Pathway	WP_OMEGA9_FATTY_ACID_SYNTHESIS	FADS1 ELOVL5 ELOVL3	1.88e-05	14	54	3	M39780
Pathway	WP_OMEGA9_FATTY_ACID_SYNTHESIS	FADS1 ELOVL5 ELOVL3	1.88e-05	14	54	3	MM15840
Pathway	REACTOME_SPHINGOLIPID_METABOLISM	ACER1 PLPP3 CERS3 UGT8 CERS1	2.61e-05	92	54	5	MM15086
Pathway	REACTOME_SPHINGOLIPID_METABOLISM	ACER1 PLPP3 CERS3 UGT8 CERS1	5.40e-05	107	54	5	M14857
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	TRPM6 CLCN3 CLCN4 CLCN5 ATP13A5 ATP6V0A2	6.79e-05	183	54	6	M997
Pathway	WP_SYNTHESIS_OF_CERAMIDES_AND_1DEOXYCERAMIDES	CERS3 UGT8 CERS1	7.77e-05	22	54	3	M45544
Pathway	WP_SPHINGOLIPID_PATHWAY	ACER1 CERS3 UGT8	2.00e-04	30	54	3	M39501
Pathway	WP_LINOLEIC_ACID_METABOLISM_AFFECTED_BY_SARSCOV2	FADS1 ELOVL5	2.14e-04	6	54	2	M42575
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC12A6 SLC8A2 SLC8A3 SLC22A15 MFSD4B SLC1A7	3.63e-04	249	54	6	M5988
Pathway	KEGG_SPHINGOLIPID_METABOLISM	ACER1 PLPP3 UGT8	4.40e-04	39	54	3	M15955
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	TRPM6 CLCN4 CLCN5 ATP13A5 ATP6V0A2	5.53e-04	176	54	5	MM15718
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPM6 CLCN3 CLCN4 CLCN5	7.15e-04	106	54	4	M27200
Pathway	WP_CHOLESTEROL_METABOLISM_WITH_BLOCH_AND_KANDUTSCHRUSSELL_PATHWAYS	FADS1 ELOVL5 ELOVL3	7.65e-04	47	54	3	M39853
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC12A6 SLC8A2 SLC8A3 SLC1A7	7.67e-04	108	54	4	M823
Pathway	REACTOME_SODIUM_CALCIUM_EXCHANGERS	SLC8A2 SLC8A3	7.75e-04	11	54	2	M27336
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC12A6 SLC8A2 SLC8A3 SLC1A7	7.94e-04	109	54	4	MM15074
Pathway	REACTOME_SPHINGOLIPID_CATABOLISM	ACER1 PLPP3	9.27e-04	12	54	2	M48264
Pathway	REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS	SLC8A2 SLC8A3	9.27e-04	12	54	2	M27326
Pathway	REACTOME_SPHINGOLIPID_CATABOLISM	ACER1 PLPP3	9.27e-04	12	54	2	MM17238
Pathway	WP_CHOLESTEROL_METABOLISM_WITH_BLOCH_AND_KANDUTSCHRUSSELL_PATHWAYS	FADS1 ELOVL5 ELOVL3	1.03e-03	52	54	3	MM15920
Pathway	REACTOME_MUSCLE_CONTRACTION	SLC8A2 SLC8A3 SCN7A SCN8A CACNA1I	1.05e-03	203	54	5	M5485
Pathway	REACTOME_SODIUM_CALCIUM_EXCHANGERS	SLC8A2 SLC8A3	1.09e-03	13	54	2	MM15078
Pathway	REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS	SLC8A2 SLC8A3	1.27e-03	14	54	2	MM15052
Pathway	WP_OMEGA3_OMEGA6_FATTY_ACID_SYNTHESIS	FADS1 ELOVL5	1.46e-03	15	54	2	M39789
Pathway	REACTOME_CARDIAC_CONDUCTION	SLC8A2 SLC8A3 SCN7A SCN8A	1.53e-03	130	54	4	M27454
Pathway	WP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM	VANGL2 CELSR1 SMO	1.56e-03	60	54	3	M40048
Pathway	WP_OMEGA3_OMEGA6_FATTY_ACID_SYNTHESIS	FADS1 ELOVL5	1.67e-03	16	54	2	MM15813
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC12A6 SLC8A2 SLC8A3 SLC22A15 SLC1A7	2.12e-03	238	54	5	MM15076
Pathway	REACTOME_METABOLISM_OF_LIPIDS	FADS1 ACER1 PLPP3 CERS3 ELOVL5 UGT8 ELOVL3 CERS1	2.33e-03	620	54	8	MM15193
Pathway	WP_GPCRS_ORPHAN	GPR89B GPR89A	2.36e-03	19	54	2	MM15991
Pathway	WP_METABOLISM_OF_SPHINGOLIPIDS_IN_ER_AND_GOLGI_APPARATUS	CERS3 UGT8	2.89e-03	21	54	2	M39459
Pathway	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	ELOVL5 ELOVL3	3.17e-03	22	54	2	MM15451
Pathway	KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS	FADS1 ELOVL5	3.17e-03	22	54	2	M11673
Pathway	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	ELOVL5 ELOVL3	3.77e-03	24	54	2	M1016
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	SLC8A2 SLC8A3 HRH1 CACNA1I	4.75e-03	178	54	4	M2890
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	SLC8A2 SLC8A3	4.75e-03	27	54	2	MM15053
Pathway	REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS	CERS3 CERS1	4.75e-03	27	54	2	MM14646
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	SLC8A2 SLC8A3	5.11e-03	28	54	2	M924
Pathway	WP_GPCRS_OTHER	CELSR1 SMO ALG6	5.41e-03	93	54	3	M39629
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN7A SCN8A	6.24e-03	31	54	2	M877
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPM6 CLCN4 CLCN5	6.43e-03	99	54	3	MM14910
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN7A SCN8A	6.64e-03	32	54	2	M27455
Pathway	REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	ELOVL5 ELOVL3	6.64e-03	32	54	2	MM15446
Pubmed	Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.	CERS3 ELOVL5 UGT8 ELOVL3 CERS1	2.39e-09	27	71	5	25269881
Pubmed	Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation.	CLCN3 CLCN4 CLCN5	3.26e-08	4	71	3	20351103
Pubmed	An essential role for ClC-4 in transferrin receptor function revealed in studies of fibroblasts derived from Clcn4-null mice.	CLCN3 CLCN4 CLCN5	8.13e-08	5	71	3	19339555
Pubmed	Expression of CLCN voltage-gated chloride channel genes in human blood vessels.	CLCN3 CLCN4 CLCN5	1.62e-07	6	71	3	10198195
Pubmed	Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.	FADS1 CERS3 ELOVL5 CERS1	3.64e-07	29	71	4	38485951
Pubmed	Changing expression of chloride channels during preimplantation mouse development.	CLCN3 CLCN4 CLCN5	6.79e-07	9	71	3	23115349
Pubmed	Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production.	CERS3 ELOVL5 ELOVL3	1.33e-06	11	71	3	23689133
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	VANGL2 SLC12A6 GPR89B BET1 SCAMP1 KTN1 ELOVL5 GPR89A UGT8 MFSD4B ALG6	3.49e-06	952	71	11	38569033
Pubmed	Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.	CLCN3 CLCN4	4.11e-06	2	71	2	32118314
Pubmed	Preferential involvement of Na⁺/Ca²⁺ exchanger type-1 in the brain damage caused by transient focal cerebral ischemia in mice.	SLC8A2 SLC8A3	4.11e-06	2	71	2	23137542
Pubmed	Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition.	FADS1 ELOVL5	4.11e-06	2	71	2	21383846
Pubmed	Na+/Ca2+ exchanger mediates cold Ca2+ signaling conserved for temperature-compensated circadian rhythms.	SLC8A2 SLC8A3	4.11e-06	2	71	2	33931447
Pubmed	A novel gene, FAM11A, associated with the FRAXF CpG island is transcriptionally silent in FRAXF full mutation.	TMEM185B TMEM185A	4.11e-06	2	71	2	12404111
Pubmed	Identification and functional characterization of a voltage-gated chloride channel and its novel splice variant in taste bud cells.	CLCN4 CLCN5	4.11e-06	2	71	2	16129671
Pubmed	Celsr1 is required for the generation of polarity at multiple levels of the mouse oviduct.	VANGL2 CELSR1	4.11e-06	2	71	2	25406397
Pubmed	Preferential association with ClC-3 permits sorting of ClC-4 into endosomal compartments.	CLCN3 CLCN4	4.11e-06	2	71	2	28972156
Pubmed	GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.	GPR89B GPR89A	4.11e-06	2	71	2	18794847
Pubmed	The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease.	SLC8A2 SLC8A3	4.11e-06	2	71	2	23224884
Pubmed	Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.	SLC8A2 SLC8A3	4.11e-06	2	71	2	19667209
Pubmed	Chloride/proton antiporters ClC3 and ClC5 support bone formation in mice.	CLCN3 CLCN5	4.11e-06	2	71	2	38666049
Pubmed	GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier.	GPR89B GPR89A	4.11e-06	2	71	2	22572823
Pubmed	Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.	CLCN4 CLCN5	4.11e-06	2	71	2	16034421
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CLCN3 CLCN4 CLCN5 SCN7A SCN8A	9.99e-06	139	71	5	16985003
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	SLC8A2 MARCHF6 ELOVL5 HRH1 UGT8 SMO CERS1 ATP6V0A2 TSPAN33	1.22e-05	697	71	9	28298427
Pubmed	Evidence of evolutionary up-regulation of the single active X chromosome in mammals based on Clc4 expression levels in Mus spretus and Mus musculus.	CLCN4 CLCN5	1.23e-05	3	71	2	9256467
Pubmed	Structure-Dynamic Coupling Through Ca2+-Binding Regulatory Domains of Mammalian NCX Isoform/Splice Variants.	SLC8A2 SLC8A3	1.23e-05	3	71	2	29594857
Pubmed	Identification of genes and pathways involved in the synthesis of Mead acid (20:3n-9), an indicator of essential fatty acid deficiency.	FADS1 ELOVL5	1.23e-05	3	71	2	24184513
Pubmed	Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.	GPR89B GPR89A	1.23e-05	3	71	2	32220963
Pubmed	Aberrant Amygdala-Dependent Cued Fear Memory in Na+/Ca2+ Exchanger 1 Heterozygous Mice.	SLC8A2 SLC8A3	1.23e-05	3	71	2	30324228
Pubmed	The downregulation of NCXs is positively correlated with the prognosis of stage II-IV colon cancer.	SLC8A2 SLC8A3	1.23e-05	3	71	2	34127021
Pubmed	Sodium-calcium exchange in intracellular calcium handling of human airway smooth muscle.	SLC8A2 SLC8A3	1.23e-05	3	71	2	21858195
Pubmed	Immunosuppressive drugs, immunophilins, and functional expression of NCX isoforms.	SLC8A2 SLC8A3	1.23e-05	3	71	2	23224887
Pubmed	New roles of NCX in glial cells: activation of microglia in ischemia and differentiation of oligodendrocytes.	SLC8A2 SLC8A3	1.23e-05	3	71	2	23224890
Pubmed	Genetically modified mice as a strategy to unravel the role played by the Na(+)/Ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits.	SLC8A2 SLC8A3	1.23e-05	3	71	2	23224882
Pubmed	Gene expression of desaturase (FADS1 and FADS2) and Elongase (ELOVL5) enzymes in peripheral blood: association with polyunsaturated fatty acid levels and atopic eczema in 4-year-old children.	FADS1 ELOVL5	1.23e-05	3	71	2	24167612
Pubmed	High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease.	SLC8A2 SLC8A3	1.23e-05	3	71	2	21382638
Pubmed	Three Na+/Ca2+ exchanger (NCX) variants are expressed in mouse osteoclasts and mediate calcium transport during bone resorption.	SLC8A2 SLC8A3	1.23e-05	3	71	2	17317768
Pubmed	Support of bone mineral deposition by regulation of pH.	CLCN3 CLCN5	1.23e-05	3	71	2	30044661
Pubmed	Primary cilia in murine palatal rugae development.	VANGL2 CELSR1 SMO	1.40e-05	23	71	3	31226309
Pubmed	Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.	VANGL2 CELSR1 SCN8A ELOVL3	1.48e-05	72	71	4	25917818
Pubmed	Large-scale concatenation cDNA sequencing.	FADS1 CLCN4 ZDHHC23 PLPP3 SV2B SCAMP1 ELOVL5 XPR1	2.08e-05	568	71	8	9110174
Pubmed	A "double adaptor" method for improved shotgun library construction.	FADS1 CLCN4 ZDHHC23 PLPP3 SV2B SCAMP1 ELOVL5 XPR1	2.24e-05	574	71	8	8619474
Pubmed	Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.	ACER1 CERS3 CERS1	2.30e-05	27	71	3	23096701
Pubmed	Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes.	VANGL2 CELSR1	2.46e-05	4	71	2	33529151
Pubmed	Calcineurin inhibits Na+/Ca2+ exchange in phenylephrine-treated hypertrophic cardiomyocytes.	SLC8A2 SLC8A3	2.46e-05	4	71	2	15557343
Pubmed	A contravention of Ohno's law in mice.	CLCN4 CLCN5	2.46e-05	4	71	2	7670497
Pubmed	Different chromosomal localization of the Clcn4 gene in Mus spretus and C57BL/6J mice.	CLCN4 CLCN5	2.46e-05	4	71	2	7670496
Pubmed	Mutational analysis of CLC-5, cofilin and CLC-4 in patients with Dent's disease.	CLCN4 CLCN5	2.46e-05	4	71	2	19546591
Pubmed	Behavioural profiles of neurological mutant mice.	VANGL2 CDH23	2.46e-05	4	71	2	5955164
Pubmed	Reduced expression of Na+/Ca2+ exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice.	SLC8A2 SLC8A3	2.46e-05	4	71	2	29274751
Pubmed	Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.	VANGL2 CELSR1	2.46e-05	4	71	2	29463853
Pubmed	Cerebellar Neurodegeneration and Neuronal Circuit Remodeling in Golgi pH Regulator-Deficient Mice.	GPR89B GPR89A	2.46e-05	4	71	2	31118204
Pubmed	Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters.	CLCN3 CLCN5	2.46e-05	4	71	2	17110406
Pubmed	Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids.	ELOVL5 ELOVL3	2.46e-05	4	71	2	10970790
Pubmed	Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.	VANGL2 CELSR1	2.46e-05	4	71	2	16687519
Pubmed	Hypoxia up-regulates glyceraldehyde-3-phosphate dehydrogenase in mouse brain capillary endothelial cells: involvement of Na+/Ca2+ exchanger.	SLC8A2 SLC8A3	2.46e-05	4	71	2	12581871
Pubmed	Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice.	VANGL2 CELSR1	4.09e-05	5	71	2	25128525
Pubmed	New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo.	VANGL2 CELSR1	4.09e-05	5	71	2	34463728
Pubmed	Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice.	VANGL2 CELSR1	4.09e-05	5	71	2	23996638
Pubmed	Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor.	TMEM185B TMEM185A	4.09e-05	5	71	2	15525354
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	VANGL2 BET1 KTN1 GPR89A UGT8 CERS1 ATP6V0A2	4.84e-05	468	71	7	31056421
Pubmed	Ion channel expression in the developing enteric nervous system.	CLCN3 CLCN4 CLCN5	6.03e-05	37	71	3	25798587
Pubmed	Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns.	VANGL2 CELSR1	6.13e-05	6	71	2	28599846
Pubmed	Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity.	VANGL2 CELSR1	6.13e-05	6	71	2	36712970
Pubmed	Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine.	CERS3 CERS1	6.13e-05	6	71	2	17977534
Pubmed	Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases.	CERS3 CERS1	6.13e-05	6	71	2	23936132
Pubmed	Sodium/calcium exchanger expression in the mouse and rat olfactory systems.	SLC8A2 SLC8A3	6.13e-05	6	71	2	17311327
Pubmed	Epidermal wound repair is regulated by the planar cell polarity signaling pathway.	VANGL2 CELSR1	6.13e-05	6	71	2	20643356
Pubmed	Celsr1 coordinates the planar polarity of vestibular hair cells during inner ear development.	VANGL2 CELSR1	6.13e-05	6	71	2	28159525
Pubmed	Patterning of papillae on the mouse tongue: A system for the quantitative assessment of planar cell polarity signaling.	VANGL2 CELSR1	6.13e-05	6	71	2	27612405
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	SLC8A2 SLC8A3 CACNA1I	6.53e-05	38	71	3	30786075
Pubmed	Mitotic internalization of planar cell polarity proteins preserves tissue polarity.	VANGL2 CELSR1	8.57e-05	7	71	2	21743464
Pubmed	Gene expression profiling of arthritis using a QTL chip reveals a complex gene regulation of the Cia5 region in mice.	GPR89B GPR89A	8.57e-05	7	71	2	16015370
Pubmed	Inhibitory interaction of the plasma membrane Na+/Ca2+ exchangers with the 14-3-3 proteins.	SLC8A2 SLC8A3	8.57e-05	7	71	2	16679322
Pubmed	Na+/Ca2+ exchanger-deficient mice have disorganized myofibrils and swollen mitochondria in cardiomyocytes.	SLC8A2 SLC8A3	8.57e-05	7	71	2	12781968
Pubmed	PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice.	PIEZO2 CDH23	8.57e-05	7	71	2	34244441
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	ZDHHC2 CLCN3 CLCN5 BET1 SCAMP1 MARCHF6 CERS1 MFSD4B	1.08e-04	719	71	8	35337019
Pubmed	Frizzled3 and Frizzled6 Cooperate with Vangl2 to Direct Cochlear Innervation by Type II Spiral Ganglion Neurons.	VANGL2 CELSR1	1.47e-04	9	71	2	31462532
Pubmed	The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.	VANGL2 CELSR1	1.47e-04	9	71	2	20704721
Pubmed	A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth.	VANGL2 CDH23	1.47e-04	9	71	2	18339676
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	GPR89B CELSR1 DIPK1A KTN1 MARCHF6 ELOVL5 UGT8 CERS1 ALG6 ATP6V0A2	1.58e-04	1201	71	10	35696571
Pubmed	ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.	ELOVL5 ELOVL3	1.83e-04	10	71	2	20937905
Pubmed	Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis.	VANGL2 CELSR1	1.83e-04	10	71	2	30283008
Pubmed	Domineering non-autonomy in Vangl1;Vangl2 double mutants demonstrates intercellular PCP signaling in the vertebrate inner ear.	VANGL2 CELSR1	1.83e-04	10	71	2	29510119
Pubmed	Protein Binder Toolbox for Studies of Solute Carrier Transporters.	SLC12A6 SCAMP1 ATP6V0A2	2.09e-04	56	71	3	38878854
Pubmed	Loss of Zic3 impairs planar cell polarity leading to abnormal left-right signaling, heart defects and neural tube defects.	VANGL2 CELSR1	2.23e-04	11	71	2	34274973
Pubmed	A dual role for planar cell polarity genes in ciliated cells.	VANGL2 CELSR1	2.23e-04	11	71	2	25024228
Pubmed	Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo.	VANGL2 CELSR1	2.68e-04	12	71	2	23406901
Pubmed	Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production.	ABCA12 CERS3	2.68e-04	12	71	2	31356814
Pubmed	Microtubules enable the planar cell polarity of airway cilia.	VANGL2 CELSR1	2.68e-04	12	71	2	23122850
Pubmed	Identification of ligands for olfactory receptors by functional expression of a receptor library.	OR6A2 OR1P1	2.68e-04	12	71	2	9875846
Pubmed	Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.	VANGL2 CELSR1	3.16e-04	13	71	2	27789626
Pubmed	The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations.	CERS3 UGT2B10	3.16e-04	13	71	2	25293881
Pubmed	Autosomal Recessive Congenital Ichthyosis	ABCA12 CERS3	3.16e-04	13	71	2	20301593
Pubmed	Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles.	VANGL2 CELSR1	3.16e-04	13	71	2	18849982
Pubmed	Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure.	VANGL2 CELSR1	3.16e-04	13	71	2	17229766
Pubmed	A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.	VANGL2 CELSR1	3.16e-04	13	71	2	26989192
Pubmed	The ciliary GTPase Arl3 maintains tissue architecture by directing planar spindle orientation during epidermal morphogenesis.	VANGL2 CELSR1	3.16e-04	13	71	2	30952667
Pubmed	Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.	VANGL2 CELSR1	3.16e-04	13	71	2	27597235
Pubmed	Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation.	VANGL2 CELSR1	3.68e-04	14	71	2	38569553
Interaction	TTYH1 interactions	VANGL2 SLC12A6 FADS1 BET1 GPR89A UGT8 SMO LRRC8B XPR1	6.39e-07	300	67	9	int:TTYH1
Interaction	SCN4A interactions	DIPK1A SCN8A GPR89A UGT8 SMO	1.87e-05	98	67	5	int:SCN4A
Interaction	OR10H2 interactions	SLC12A6 CLCN3 SMO XPR1	9.68e-05	72	67	4	int:OR10H2
Interaction	TMEM9 interactions	SLC12A6 CLCN3 CLCN4 CLCN5 ELOVL5 XPR1	1.05e-04	226	67	6	int:TMEM9
Interaction	GPR21 interactions	SLC12A6 FADS1 MARCHF6 GPR89A	1.53e-04	81	67	4	int:GPR21
Interaction	RAB5C interactions	VANGL2 SLC12A6 PLPP3 BET1 SCAMP1 KTN1 GPR89A CERS1 XPR1	1.59e-04	600	67	9	int:RAB5C
Interaction	TMEM185B interactions	TMEM185B TMEM185A	1.62e-04	6	67	2	int:TMEM185B
Interaction	TMEM216 interactions	VANGL2 BET1 SCAMP1 KTN1 GPR89A UGT8	1.67e-04	246	67	6	int:TMEM216
Interaction	LAMP3 interactions	VANGL2 ZDHHC2 PLPP3 BET1 SCAMP1 KTN1 GPR89A XPR1	2.02e-04	486	67	8	int:LAMP3
Interaction	CRELD1 interactions	BET1 ELOVL5 GPR89A UGT8 ALG6	2.10e-04	163	67	5	int:CRELD1
Interaction	ERICH5 interactions	ZDHHC23 TMEM185A ATP6V0A2	2.13e-04	35	67	3	int:ERICH5
Interaction	RNF148 interactions	RNF148 ATP6V0A2	2.26e-04	7	67	2	int:RNF148
GeneFamily	Chloride voltage-gated channels	CLCN3 CLCN4 CLCN5	2.81e-06	10	53	3	302
GeneFamily	CERS class homeoboxes	CERS3 CERS1	1.26e-04	6	53	2	530
GeneFamily	Solute carriers	SLC12A6 SLC8A2 SLC8A3 SLC37A3 SLC22A15 SLC35G2 SLC1A7	1.46e-04	395	53	7	752
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC2 ZDHHC23	2.23e-03	24	53	2	76
GeneFamily	UDP glucuronosyltransferases	UGT2B10 UGT8	3.95e-03	32	53	2	363
GeneFamily	Olfactory receptors, family 6	OR6A2 OR6Q1	9.81e-03	51	53	2	153
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CELSR1 PIEZO2 CLCN5 SCN8A TSPAN33	6.30e-06	163	71	5	f4fcac0af9967ec34a43c9674aa17b0aa5344cf6
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACER1 SLC22A15 UGT8 CDH23 ALG6	7.95e-06	171	71	5	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACER1 SLC22A15 UGT8 CDH23 ALG6	7.95e-06	171	71	5	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	MCTP1 PLPP3 HRH1 CDH23 C1S	1.32e-05	190	71	5	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS1 PLPP3 ELOVL5 UGT8 LRRC8B	1.61e-05	198	71	5	a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Rorb-Excitatory_Neuron.Sc17a7.Rorb-Gpr83_(Layer_5a)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SCN7A ADGRF4 TMEM225 PTH2R	2.70e-05	108	71	4	5af010a1ee6535b144ccd16999c225508a4b3433
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Efna5_(Deep_layer_pyramidal_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ELOVL3 TMEM225 SLC1A7	8.82e-05	54	71	3	13431c23a110070a11de41773233a8d6583d902c
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Efna5_(Deep_layer_pyramidal_cells)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ELOVL3 TMEM225 SLC1A7	8.82e-05	54	71	3	cd64ee5c47df5dba0cea954cb115a8de0efb55d1
ToppCell	Children_(3_yrs)-Immune-mast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC8A3 ACER1 CACNA1I PTH2R	1.05e-04	153	71	4	d3fb83ca984c7583b1e51c364be6c7c17f67b048
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ACER1 PLPP3 MAP3K6 XPR1	1.13e-04	156	71	4	0b3630fd4479291599e1674e87eba6f93877ac3a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CELSR1 ZDHHC23 UGT8 TSPAN33	1.13e-04	156	71	4	4e4b94580969a9736ca28df79715535a4bd1f9b2
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC8A2 SV2B SCN7A CACNA1I	1.16e-04	157	71	4	5aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	VANGL2 ABCA12 SMO TSPAN33	1.16e-04	157	71	4	19c0599a669803c4db1f174de1ce755e562a50a3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM185B CLCN5 UGT8 PTH2R	1.21e-04	159	71	4	c186bf05c61fac348cf41973827cced83fafd58a
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA12 ADGRF4 PTH2R SECTM1	1.30e-04	162	71	4	075f73ff10e1a7f5695e014e47acc4db513e9cfb
ToppCell	10x5'-lymph-node_spleen-Mast-Mast_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	VANGL2 TRPM6 SLC8A3 SCN7A	1.50e-04	168	71	4	650ad3ea52577887885d82457dbc04202ce3eb34
ToppCell	367C-Fibroblasts-Fibroblast-G\|367C / Donor, Lineage, Cell class and subclass (all cells)	SLC8A2 PLPP3 SCN7A C1S	1.50e-04	168	71	4	8c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell	10x5'-lymph-node_spleen-Mast\|lymph-node_spleen / Manually curated celltypes from each tissue	VANGL2 TRPM6 SLC8A3 SCN7A	1.50e-04	168	71	4	e58ffbb57c81967766755c3f6f347b158a39cb0d
ToppCell	367C-Fibroblasts-Fibroblast-G-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SLC8A2 PLPP3 SCN7A C1S	1.50e-04	168	71	4	b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	FADS1 CLCN5 CDH23 HS3ST3B1	1.79e-04	176	71	4	d6e660df92a3d7dd5732171ee623763faf108476
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VANGL2 CLCN5 SCN7A MFSD4B	1.79e-04	176	71	4	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VANGL2 CLCN5 SCN7A MFSD4B	1.79e-04	176	71	4	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SSMEM1 C1S ATP13A5	1.83e-04	69	71	3	a157b1582401cebd222343d94086dbea876140c2
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SSMEM1 C1S ATP13A5	1.83e-04	69	71	3	cdd42abdd072aa438830d837ee857529269a81e0
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 PLPP3 SCN7A C1S	1.83e-04	177	71	4	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	GPR89B CLCN5 ZDHHC23 UGT8	1.83e-04	177	71	4	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 PLPP3 SCN7A C1S	1.83e-04	177	71	4	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	PBMC-Severe-cDC_11\|Severe / Compartment, Disease Groups and Clusters	CLCN4 PLPP3 SMO TSPAN33	1.87e-04	178	71	4	0667abc05eb2254710b9c648c65b7cfdfe7831b7
ToppCell	facs-Skin-Anagen-3m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACER1 ABCA12 CERS3 ADGRF4	1.91e-04	179	71	4	4a072526c3a524a7aed99bdb32a07a1ce1f48972
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-5\|TCGA-Colorectal / Sample_Type by Project: Shred V9	CLCN3 ABCA12 UGT8 RNF145	1.99e-04	181	71	4	8fcc9e77fee7c248df26b6c59b10e672242e2084
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A C1S SLC35G2 CFAP46	1.99e-04	181	71	4	c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 SCN7A SLC22A15 TMEM225	2.04e-04	182	71	4	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZDHHC23 SV2B DNAH7 CFAP46	2.04e-04	182	71	4	14a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCell	3'_v3-GI_small-bowel-Myeloid_Dendritic-DC1\|GI_small-bowel / Manually curated celltypes from each tissue	CLCN4 PLPP3 SMO TSPAN33	2.12e-04	184	71	4	8e393eea7240584a3cef718bee094e2705ec1891
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCTP1 ZDHHC23 HRH1 PTH2R	2.12e-04	184	71	4	ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLCN5 SCN7A UGT8 PTH2R	2.12e-04	184	71	4	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	10x5'-Liver-Myeloid_Dendritic-DC1\|Liver / Manually curated celltypes from each tissue	CLCN4 ABCA12 SMO TSPAN33	2.21e-04	186	71	4	e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCell	CF-Lymphoid-pDC\|Lymphoid / Disease state, Lineage and Cell class	FADS1 MCTP1 CLCN5 HS3ST3B1	2.26e-04	187	71	4	adc79e5804ab98006dbdf1d76ef0d8f85cc5cb0f
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	PIEZO2 PLPP3 SCN7A CDH23	2.26e-04	187	71	4	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	ACER1 ABCA12 CERS3 ADGRF4	2.26e-04	187	71	4	2ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLCN4 ZDHHC23 UGT8 TSPAN33	2.26e-04	187	71	4	d01926be1c8846a25fb6706e26b56b808b69f8f0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CLCN5 SLC22A15 UGT8	2.35e-04	189	71	4	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIEZO2 SCN7A LRRC8B MAP3K6	2.35e-04	189	71	4	09dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIEZO2 FADS1 PLPP3 C1S	2.35e-04	189	71	4	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	SupraBC-Differ-KC\|World / shred by cell class for mouse tongue	ACER1 ABCA12 CERS3 ADGRF4	2.35e-04	189	71	4	6412741b88e241304033b41effca0c77a374d907
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLCN4 ZDHHC23 UGT8 TSPAN33	2.40e-04	190	71	4	112706d64ee73b55dcf76f33ca064ab1fc6ce87f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CLCN5 SLC22A15 UGT8	2.40e-04	190	71	4	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIEZO2 FADS1 PLPP3 C1S	2.40e-04	190	71	4	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	facs-Tongue-nan-3m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACER1 ABCA12 CERS3 ADGRF4	2.40e-04	190	71	4	719a5cecc3e8001ca9c38165258b5ff9c800713a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLCN5 SCN7A UGT8 PTH2R	2.45e-04	191	71	4	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	Endothelial-B\|World / shred on cell class and cell subclass (v4)	PIEZO2 PLPP3 SCN7A MAP3K6	2.45e-04	191	71	4	8b7857dee69d0ba3e59e230c9fd372e14695299e
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIEZO2 FADS1 PLPP3 C1S	2.50e-04	192	71	4	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIEZO2 FADS1 PLPP3 C1S	2.50e-04	192	71	4	df1545670370fb1010c567cd059c2783eab315f7
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIEZO2 FADS1 PLPP3 C1S	2.50e-04	192	71	4	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIEZO2 PLPP3 SCN7A C1S	2.50e-04	192	71	4	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CELSR1 CLCN5 DNAH7 PTH2R	2.55e-04	193	71	4	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLCN4 ZDHHC23 UGT8 TSPAN33	2.55e-04	193	71	4	6e6c5ae39ea880ba809019a7d39f50e4e02007ed
ToppCell	facs-Tongue-nan-3m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACER1 ABCA12 CERS3 ADGRF4	2.55e-04	193	71	4	33437fdb417d78463caee14a9f0e094da1733829
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLCN4 ZDHHC23 UGT8 TSPAN33	2.55e-04	193	71	4	c04ac5884be4245b75d211046f04d76ae0cfb998
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CELSR1 ZDHHC23 UGT8 TSPAN33	2.55e-04	193	71	4	749faa5c592ee354733f5a7363a4277ef3462b93
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PIEZO2 PLPP3 SCN7A CDH23	2.60e-04	194	71	4	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIEZO2 SCN7A ELOVL5 LRRC8B	2.60e-04	194	71	4	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLCN5 UGT8 DNAH7 PTH2R	2.60e-04	194	71	4	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	(5)_Fibroblast-C_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	PIEZO2 PLPP3 SCN7A C1S	2.60e-04	194	71	4	29a72e565c19407bbd198cfbc2a78106fe830d05
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIEZO2 PLPP3 SCN7A C1S	2.65e-04	195	71	4	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CLCN5 UGT8 DNAH7 PTH2R	2.65e-04	195	71	4	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIEZO2 PLPP3 SCN7A C1S	2.65e-04	195	71	4	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	15-Distal-Mesenchymal\|Distal / Age, Tissue, Lineage and Cell class	PIEZO2 PLPP3 SCN7A C1S	2.70e-04	196	71	4	b8d95b5f4780e73d16dcc528e70a5496f0314373
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIEZO2 PLPP3 SCN7A C1S	2.70e-04	196	71	4	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIEZO2 PLPP3 SCN7A C1S	2.70e-04	196	71	4	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLCN5 UGT8 DNAH7 PTH2R	2.70e-04	196	71	4	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLCN5 UGT8 DNAH7 PTH2R	2.70e-04	196	71	4	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIEZO2 PLPP3 SCN7A C1S	2.70e-04	196	71	4	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VANGL2 TEX261 CLCN3 PLPP3	2.70e-04	196	71	4	45d1c0a962c4221c17393ee5566961d1deebf442
ToppCell	368C-Fibroblasts-Fibroblast-G\|368C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 PLPP3 SCN7A C1S	2.75e-04	197	71	4	156155c2f0c1a2461e45803da578af18ee221660
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIEZO2 PLPP3 SCN7A C1S	2.75e-04	197	71	4	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ACER1 SCN7A C1S HS3ST3B1	2.75e-04	197	71	4	d7cef7881abd807a679432766ced609a6efd1067
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	PIEZO2 PLPP3 SCN7A C1S	2.75e-04	197	71	4	6c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell	368C-Fibroblasts-Fibroblast-G-\|368C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 PLPP3 SCN7A C1S	2.75e-04	197	71	4	d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ACER1 SCN7A C1S HS3ST3B1	2.75e-04	197	71	4	20a5958512bdb99daeb8f4d244df53e4f048f879
ToppCell	tumor_Lung-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	PIEZO2 PLPP3 SCN7A C1S	2.75e-04	197	71	4	44f37a98f07c3e46a7e8fd3b64c2b2b44d5bbe40
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIEZO2 PLPP3 SCN7A C1S	2.75e-04	197	71	4	13896ec65ccda0b928c91d41112dc01b480036b7
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS1 PLPP3 ELOVL5 UGT8	2.81e-04	198	71	4	731a90f7e68b19e387499d63e3979af78b503b0c
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PIEZO2 SCN7A CDH23 C1S	2.81e-04	198	71	4	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	tumor_Lung-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	PIEZO2 PLPP3 SCN7A C1S	2.81e-04	198	71	4	2d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCell	15-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	PIEZO2 PLPP3 SCN7A C1S	2.81e-04	198	71	4	3d76393e72eed59b4dd16130ef5dd1d331ba5711
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 PLPP3 SCN7A C1S	2.81e-04	198	71	4	a9afedbc0556faf4a46f7bf28f4a9adb3bc859d8
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	TRPM6 MCTP1 PLPP3 LRRC8B	2.81e-04	198	71	4	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLPP3 HRH1 C1S XPR1	2.81e-04	198	71	4	399760b6b6fef8639ded53b14f251b9fce600e81
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 PLPP3 SCN7A C1S	2.81e-04	198	71	4	7b5350768f306ec528e271d2ac4470bf668ec6f0
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PIEZO2 PLPP3 SCN7A C1S	2.81e-04	198	71	4	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PIEZO2 PLPP3 SCN7A C1S	2.86e-04	199	71	4	7f4840ae6a888380feca722543e5e52783f3e35d
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PIEZO2 PLPP3 SCN7A C1S	2.86e-04	199	71	4	28c1722deef3b8347371c7359be7c64b95780de3
ToppCell	proximal-3-mesenchymal-Alveolar_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PIEZO2 PLPP3 SCN7A C1S	2.86e-04	199	71	4	301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCell	wk_08-11-Mesenchymal-Fibroblast-intermediate_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PIEZO2 PLPP3 SCN7A C1S	2.86e-04	199	71	4	f9e3fb974ba8fe1b6d99892577549ef143df9e08
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PIEZO2 PLPP3 SCN7A C1S	2.86e-04	199	71	4	9a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell	(5)_Fibroblast-G\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	PIEZO2 PLPP3 SCN7A C1S	2.86e-04	199	71	4	b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PIEZO2 PLPP3 SCN7A C1S	2.86e-04	199	71	4	fb23ecce41e31e2cc01814e3c0add756f489561f
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PIEZO2 PLPP3 HRH1 C1S	2.86e-04	199	71	4	95d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCell	18-Distal-Mesenchymal\|Distal / Age, Tissue, Lineage and Cell class	PIEZO2 PLPP3 SCN7A C1S	2.86e-04	199	71	4	d65150d2e24c40aa82712e7f034f6772102bd293
Drug	niflumic acid	SLC12A6 CLCN3 CLCN4 CLCN5 GLRA1 UGT8	2.39e-06	125	70	6	CID000004488
Disease	Dent disease (implicated_via_orthology)	CLCN3 CLCN4 CLCN5	1.17e-08	3	68	3	DOID:0050699 (implicated_via_orthology)
Disease	osteopetrosis (implicated_via_orthology)	CLCN3 CLCN4 CLCN5	4.07e-07	7	68	3	DOID:13533 (implicated_via_orthology)
Disease	NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO	VANGL2 CELSR1	1.45e-04	8	68	2	C3891448
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN7A SCN8A	2.33e-04	10	68	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN7A SCN8A	2.33e-04	10	68	2	DOID:0080422 (implicated_via_orthology)
Disease	Congenital ichthyosis of skin	ABCA12 CERS3	2.84e-04	11	68	2	cv:C0020758
Disease	Congenital Nonbullous Ichthyosiform Erythroderma	ABCA12 CERS3	2.84e-04	11	68	2	C0079154
Disease	phenylacetylglutamine measurement	SV2B LRRC8B	3.40e-04	12	68	2	EFO_0021013
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN7A SCN8A	3.40e-04	12	68	2	DOID:0060170 (implicated_via_orthology)
Disease	epilepsy (implicated_via_orthology)	SLC12A6 SCN7A SCN8A SLC1A7	5.55e-04	163	68	4	DOID:1826 (implicated_via_orthology)
Disease	pro-hydroxy-pro measurement	TRPM6 MCTP1	6.15e-04	16	68	2	EFO_0021132
Disease	cotinine glucuronidation measurement	CERS3 UGT2B10	8.72e-04	19	68	2	EFO_0006508
Disease	necrotizing enterocolitis	MCTP1 SLC37A3	1.77e-03	27	68	2	EFO_0003928
Disease	lysophosphatidylethanolamine 20:4 measurement	FADS1 CACNA1I	2.04e-03	29	68	2	EFO_0010370
Disease	suicidal ideation	CDH23 CFAP46	2.04e-03	29	68	2	EFO_0004320

Protein segments in the cluster

Peptide	Gene	Start	Entry
MVLVFLLVVSYWLFY	VANGL2	186	Q9ULK5
MLFSLFVFFIIYWII	BET1	101	O15155
MYGIIQFISALLLYW	ATP13A5	911	Q4VNC0
SRYIYVVWVLFMIIG	ACER1	56	Q8TDN7
NFLFFLVYFNIIIMW	ALG6	481	Q9Y672
LILADSFIYFLIAWY	ABCA12	1256	Q86UK0
SLFFWMLFKALLIIY	ADGRF4	486	Q8IZF3
YFLVYNASVLYWQMV	CFAP46	126	Q8IYW2
LNYLMYILWALLFAF	CLCN4	151	P51793
ILLHYIYMSTFAWTL	CELSR1	2536	Q9NYQ6
LFLAAMLFVLMNWYY	CDH23	3076	Q9H251
LDVVWFFLLLMSYLF	OR4D2	206	P58180
LFAMLCVWLYMFLYS	HS3ST3B1	36	Q9Y662
FVLFLFVVWNFELYM	MCTP1	811	Q6DN14
WLYFQIGYMISLIAL	ELOVL5	231	Q9NYP7
IWYLVSVMETFLLYQ	MAP3K6	471	O95382
VFWTVYYMLEVYLSQ	PCSK7	676	Q16549
MFLHWLVGMVYVFYF	MARCHF6	421	O60337
IFLFFWLFMKETLYD	KTN1	21	Q86UP2
MYFFLTHLSCLEIWY	OR6Q1	61	Q8NGQ2
YVDIWALGVLLYFMV	NIM1K	251	Q8IY84
VFWYYITLIMLLVAV	LRRC8B	26	Q6P9F7
NLLWAYAVIGTYMFL	MFSD4B	181	Q5TF39
YYILEMSFYWSLLFR	CERS3	181	Q8IU89
LTVAYYLWTTFMAVI	SLC1A7	91	O00341
YFFSIYCVWKIFMAT	GPR89A	291	B7ZAQ6
YFFSIYCVWKIFMAT	GPR89B	291	P0CG08
LFWSFILYMTYFILF	ELOVL3	236	Q9HB03
WMLLYFISFLLIVSF	CACNA1I	1406	Q9P0X4
ALLYFLLSWVTKFIY	UGT8	486	Q16880
FMYVLWALLFAFLAV	CLCN5	211	P51795
MYQYSLTWFINLFIL	DNAH7	3226	Q8WXX0
LFSLLAWVYAEPTMY	C1S	6	P09871
LTLMNLYWFLYIVAF	CERS1	291	P27544
LYWFLYIVAFAAKVL	CERS1	296	P27544
LAWMITFYVRFFLTY	FADS1	296	O60427
IINFYLPTLLMLWFY	HRH1	196	P35367
FSYVRMKYLFFSWLV	DIPK1A	21	Q5T7M9
LMFIWFVCSLVYYGL	SLC22A15	311	Q8IZD6
CLALMFISSWYYAIV	SLC12A6	691	Q9UHW9
YFFLANMSFLEIWYV	OR6A2	61	O95222
FFLLFLWMYVVTVAG	OR1P1	41	Q8NH06
LWKIFSAVFLVMYVA	OR4C6	21	Q8NH72
LILAVVWFAMAFSYY	SV2B	391	Q7L1I2
WILMSFLCLVVLYYI	TMEM185A	176	Q8NFB2
VLYYIVWSVLFLRSM	TMEM185A	186	Q8NFB2
WILMSFLCLVVLYYI	TMEM185B	176	Q9H7F4
TMLYLVLYLQARFTW	PLPP3	206	O14495
FLLWYFVIVFVLMFF	SSMEM1	41	Q8WWF3
IMISVFVLAGYKLYW	SLC35G2	381	Q8TBE7
LIFNMFYWIIYKIVR	GLRA1	436	P23415
LMYYLWMFHAVTLFL	SCAMP1	151	O15126
YIMYIFWALSFAFLA	CLCN3	211	P51790
DTMVFFYLWIVFYII	XPR1	506	Q9UBH6
LVKYLLFFFNMLFWV	TSPAN33	21	Q86UF1
KFWFYTMAYLAFLML	TRPM6	841	Q9BX84
VFILLVALVMFAWYR	SECTM1	156	Q8WVN6
WVFYFFILMTSCTIV	SLC37A3	456	Q8NCC5
WVSHYIMYLFTFLAA	RNF148	186	Q8N7C7
LDMSKVIIFSYLFWF	PIEZO2	1286	Q9H5I5
YIFILEMLLKWTAYG	SCN8A	1241	Q9UQD0
KYMIWFSTAVLIGLY	TEX261	46	Q6UWH6
VYYALMAGVVWFVVL	SMO	321	Q99835
VMFIYFLATNYYWIL	PTH2R	241	P49190
WYSVIITAGMAYIFL	ZDHHC23	356	Q8IYP9
RITWIMYTAYLNVFF	TMEM225	136	Q6GV28
KNMLYVLYFDFWFQI	UGT2B10	211	P36537
IALYWINSIFVMLYT	SCN7A	1281	Q01118
LMAYHLLFAMFVWSY	ZDHHC2	56	Q9UIJ5
FMVFWLVLFALQIYS	RNF145	231	Q96MT1
CIFGYLIFMIFYKWL	ATP6V0A2	596	Q9Y487
LIFMIFYKWLVFSAE	ATP6V0A2	601	Q9Y487
IFAYVWLYLILAVFS	SLC8A2	206	Q9UPR5
IFAYIWLYMILAVFS	SLC8A3	211	P57103