Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	IPPK CAMK1D POLR2C PBK CAMK1 PFKFB2 SIK3 PARP14 PHKA1 STK11 GUK1 TESK2 MAPK6 PPIP5K2	1.91e-04	938	98	14	GO:0016772
GeneOntologyMolecularFunction	acyltransferase activity, acyl groups converted into alkyl on transfer	ACLY HMGCS2	2.36e-04	5	98	2	GO:0046912
GeneOntologyMolecularFunction	calcium/calmodulin-dependent protein kinase activity	CAMK1D CAMK1 PHKA1	3.08e-04	27	98	3	GO:0004683
GeneOntologyMolecularFunction	kinase activity	IPPK CAMK1D PBK CAMK1 PFKFB2 SIK3 PHKA1 STK11 GUK1 TESK2 MAPK6 PPIP5K2	3.59e-04	764	98	12	GO:0016301
GeneOntologyBiologicalProcess	entrainment of circadian clock	PPP1CA PPP1CB PPP1CC GNAQ	1.19e-05	30	98	4	GO:0009649
GeneOntologyBiologicalProcess	regulation of glycogen catabolic process	PPP1CA PPP1CB PHKA1	3.64e-05	14	98	3	GO:0005981
GeneOntologyBiologicalProcess	carbohydrate metabolic process	LANCL1 PFKFB2 PPP1CA PPP1CB PPP1CC PHKA1 PHKB STK11 CHST12 FUCA2 SLC39A14 EDEM1	5.59e-05	646	98	12	GO:0005975
GeneOntologyBiologicalProcess	response to light stimulus	PBK PPP1CA PPP1CB PPP1CC STK11 NETO1 GNAQ LRRN4 HTT	8.60e-05	382	98	9	GO:0009416
GeneOntologyBiologicalProcess	alcohol biosynthetic process	IPPK ABCA2 ACLY CYP51A1 HMGCS2 PPIP5K2	9.39e-05	154	98	6	GO:0046165
GeneOntologyBiologicalProcess	glycogen metabolic process	PPP1CA PPP1CB PPP1CC PHKA1 PHKB	1.10e-04	99	98	5	GO:0005977
GeneOntologyBiologicalProcess	glucan metabolic process	PPP1CA PPP1CB PPP1CC PHKA1 PHKB	1.21e-04	101	98	5	GO:0044042
GeneOntologyCellularComponent	PTW/PP1 phosphatase complex	PPP1CA PPP1CB PPP1CC	3.56e-06	7	99	3	GO:0072357
GeneOntologyCellularComponent	protein phosphatase type 1 complex	PPP1CA PPP1CB PPP1CC	9.45e-05	19	99	3	GO:0000164
GeneOntologyCellularComponent	phosphorylase kinase complex	PHKA1 PHKB	2.20e-04	5	99	2	GO:0005964
GeneOntologyCellularComponent	ATP-binding cassette (ABC) transporter complex	ABCA2 ABCD4	3.29e-04	6	99	2	GO:0043190
GeneOntologyCellularComponent	glycogen granule	PPP1CA PPP1CB	6.10e-04	8	99	2	GO:0042587
GeneOntologyCellularComponent	perikaryon	TRPM2 RTN4RL1 GRIK3 PGR PPP1CA KNDC1	6.76e-04	223	99	6	GO:0043204
Domain	STPPase_N	PPP1CA PPP1CB PPP1CC	1.32e-07	3	96	3	IPR031675
Domain	STPPase_N	PPP1CA PPP1CB PPP1CC	1.32e-07	3	96	3	PF16891
Domain	6-hairpin_glycosidase-like	LANCL1 PHKA1 PHKB	3.63e-05	13	96	3	IPR008928
Domain	PP2Ac	PPP1CA PPP1CB PPP1CC	3.63e-05	13	96	3	SM00156
Domain	Ser/Thr-sp_prot-phosphatase	PPP1CA PPP1CB PPP1CC	3.63e-05	13	96	3	IPR006186
Domain	SER_THR_PHOSPHATASE	PPP1CA PPP1CB PPP1CC	3.63e-05	13	96	3	PS00125
Domain	Glyco_hydro_15/PHK	PHKA1 PHKB	7.82e-05	3	96	2	IPR011613
Domain	PHK_A/B_su	PHKA1 PHKB	7.82e-05	3	96	2	IPR008734
Domain	Glyco_hydro_15	PHKA1 PHKB	7.82e-05	3	96	2	PF00723
Domain	Metallophos	PPP1CA PPP1CB PPP1CC	3.93e-04	28	96	3	PF00149
Domain	Calcineurin-like_PHP_ApaH	PPP1CA PPP1CB PPP1CC	3.93e-04	28	96	3	IPR004843
Domain	Metallo-depent_PP-like	PPP1CA PPP1CB PPP1CC	4.83e-04	30	96	3	IPR029052
Domain	-	PPP1CA PPP1CB PPP1CC	4.83e-04	30	96	3	3.60.21.10
Domain	6hp_glycosidase	LANCL1 PHKA1	7.17e-04	8	96	2	IPR012341
Domain	-	LANCL1 PHKA1	7.17e-04	8	96	2	1.50.10.10
Domain	P-loop_NTPase	ABCA2 RHOD GAL3ST1 SPEF2 DDX42 MCM3 PFKFB2 EEF2 GUK1 GNA13 ABCD4 GNAQ	1.33e-03	848	96	12	IPR027417
Domain	-	ABCA2 RHOD SPEF2 DDX42 MCM3 PFKFB2 EEF2 GUK1 GNA13 ABCD4 GNAQ	1.54e-03	746	96	11	3.40.50.300
Domain	GproteinA_insert	GNA13 GNAQ	2.99e-03	16	96	2	IPR011025
Domain	-	GNA13 GNAQ	2.99e-03	16	96	2	1.10.400.10
Domain	G-alpha	GNA13 GNAQ	2.99e-03	16	96	2	PF00503
Domain	G_alpha	GNA13 GNAQ	2.99e-03	16	96	2	SM00275
Domain	Gprotein_alpha_su	GNA13 GNAQ	3.38e-03	17	96	2	IPR001019
Domain	Pkinase	CAMK1D PBK CAMK1 SIK3 STK11 TESK2 MAPK6	3.50e-03	381	96	7	PF00069
Domain	Zn_pept	CPA1 CPM	3.79e-03	18	96	2	SM00631
Domain	CARBOXYPEPT_ZN_2	CPA1 CPM	4.22e-03	19	96	2	PS00133
Domain	-	PFKFB2 PPIP5K2	4.68e-03	20	96	2	3.40.50.1240
Domain	His_PPase_superfam	PFKFB2 PPIP5K2	4.68e-03	20	96	2	IPR029033
Domain	CARBOXYPEPT_ZN_1	CPA1 CPM	4.68e-03	20	96	2	PS00132
Domain	Ca/CaM-dep_Ca-dep_prot_Kinase	CAMK1D CAMK1 STK11	5.40e-03	69	96	3	IPR020636
Domain	Peptidase_M14	CPA1 CPM	6.17e-03	23	96	2	PF00246
Domain	Peptidase_M14	CPA1 CPM	6.17e-03	23	96	2	IPR000834
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_MRAS_SHOC2_PP1_HOLOPHOSPHATASE	PPP1CA PPP1CB PPP1CC	8.95e-06	8	78	3	M47933
Pathway	KEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX	PPP1CA PPP1CB PPP1CC	3.46e-05	12	78	3	M47887
Pathway	KEGG_MEDICUS_REFERENCE_DEPHOSPHORYLATION_OF_KINETOCHORE	PPP1CA PPP1CB PPP1CC	3.46e-05	12	78	3	M47891
Pathway	KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	ARHGEF11 PPP1CA PPP1CB PPP1CC GNA13 GNAQ	4.12e-05	115	78	6	M9387
Pathway	REACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_RSV_GENOME_REPLICATION_TRANSCRIPTION_AND_TRANSLATION	PPP1CA PPP1CB PPP1CC	8.66e-05	16	78	3	M48235
Pathway	KEGG_INSULIN_SIGNALING_PATHWAY	CRKL PPP1CA PPP1CB PPP1CC PHKA1 PHKB	1.09e-04	137	78	6	M18155
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	RPN1 CALU EXPH5 ACLY TRPM2 HLCS LANCL1 PPP1CA PPP1CB PPP1CC PHKB LPP SCO1 LSM14A	9.77e-10	573	99	14	28330616
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	RPN1 CALU ASH2L PPP1CA PPP1CB PPP1CC BPTF EEF2 CNOT1	7.24e-09	203	99	9	22083510
Pubmed	1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription.	PPP1CA PPP1CB PPP1CC	2.24e-08	3	99	3	25073485
Pubmed	Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization.	PPP1CA PPP1CB PPP1CC	2.24e-08	3	99	3	7857673
Pubmed	Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.	PPP1CA PPP1CB PPP1CC	2.24e-08	3	99	3	21712997
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ABCA2 RPN1 LEMD3 CALU ACLY CYP51A1 PBK LANCL1 EEF2 CHST12 FUCA2 SLC39A14 EDEM1 DCBLD2 GPAT4 HTT DNMT1	4.83e-08	1201	99	17	35696571
Pubmed	Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein.	PPP1CA PPP1CB PPP1CC	8.93e-08	4	99	3	16131488
Pubmed	Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations.	PPP1CB PPP1CC NKX2-5	8.93e-08	4	99	3	26334248
Pubmed	Nuclear protein phosphatase-1 regulates HIV-1 transcription.	PPP1CA PPP1CB PPP1CC	8.93e-08	4	99	3	12788939
Pubmed	Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.	PPP1CA PPP1CB PPP1CC	8.93e-08	4	99	3	23277204
Pubmed	Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.	PPP1CA PPP1CB PPP1CC	8.93e-08	4	99	3	10194355
Pubmed	Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1.	PPP1CA PPP1CB PPP1CC	8.93e-08	4	99	3	22768081
Pubmed	Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.	PPP1CA PPP1CB PPP1CC	8.93e-08	4	99	3	12226088
Pubmed	N-CoR controls differentiation of neural stem cells into astrocytes.	PPP1CA PPP1CB PPP1CC	8.93e-08	4	99	3	12410313
Pubmed	Distinct roles for the α , β and γ1 isoforms of protein phosphatase 1 in the outside-in αIIbβ3 integrin signalling-dependent functions.	PPP1CA PPP1CB PPP1CC	2.23e-07	5	99	3	23197154
Pubmed	Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220.	PPP1CA PPP1CB PPP1CC	2.23e-07	5	99	3	10209101
Pubmed	The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity.	PPP1CA PPP1CB PPP1CC	2.23e-07	5	99	3	12016208
Pubmed	Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle.	PPP1CA PPP1CB PPP1CC	2.23e-07	5	99	3	11551964
Pubmed	The heterotrimeric G protein Gβ1 interacts with the catalytic subunit of protein phosphatase 1 and modulates G protein-coupled receptor signaling in platelets.	PPP1CA PPP1CB PPP1CC	2.23e-07	5	99	3	28615442
Pubmed	A PP1-PP2A phosphatase relay controls mitotic progression.	PPP1CA PPP1CB PPP1CC	2.23e-07	5	99	3	25487150
Pubmed	SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1.	PPP1CA PPP1CB PPP1CC	2.23e-07	5	99	3	20424263
Pubmed	The interaction of PP1 with BRCA1 and analysis of their expression in breast tumors.	PPP1CA PPP1CB PPP1CC	2.23e-07	5	99	3	17511879
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	RPN1 CALU ACLY DDX42 LANCL1 MCM3 ARHGEF11 ASH2L CRKL SH3PXD2A ELMO2 GNA13 LSM14A PPIP5K2	3.34e-07	916	99	14	32203420
Pubmed	SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1.	PPP1CA PPP1CB PPP1CC	4.45e-07	6	99	3	14640981
Pubmed	Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1).	PPP1CA PPP1CB PPP1CC	4.45e-07	6	99	3	25785436
Pubmed	Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif.	PPP1CA PPP1CB PPP1CC	4.45e-07	6	99	3	21998301
Pubmed	Potent activation of RhoA by Galpha q and Gq-coupled receptors.	ARHGEF11 GNA13 GNAQ	4.45e-07	6	99	3	12016230
Pubmed	Protein phosphatase 1 regulates the phosphorylation state of the polarity scaffold Par-3.	PPP1CA PPP1CB PPP1CC	4.45e-07	6	99	3	18641122
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	RPN1 ACLY MCM3 ASH2L CRKL PPP1CA BPTF LPP CNOT1 HTT DNMT1	4.95e-07	549	99	11	38280479
Pubmed	New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC).	POLR2C PPP1CA PPP1CB PPP1CC	5.25e-07	23	99	4	21360054
Pubmed	Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.	PPP1CA PPP1CB PPP1CC GPAT4	6.28e-07	24	99	4	27754788
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	RPN1 LEMD3 CALU POLR2C DDX42 MCM3 PPP1CA PPP1CB PPP1CC EEF2 LSM14A DNMT1	7.65e-07	701	99	12	30196744
Pubmed	A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta.	PPP1CA PPP1CB PPP1CC	7.77e-07	7	99	3	12147701
Pubmed	Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.	PPP1CA PPP1CB PPP1CC	7.77e-07	7	99	3	18689497
Pubmed	SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein.	PPP1CA PPP1CB PPP1CC	7.77e-07	7	99	3	17123353
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	RPN1 CALU ACLY POLR2C CYP51A1 LANCL1 PPP1CA PPP1CB PPP1CC BPTF EEF2 GNA13 SLC39A14 CDC34 CNOT1 DNMT1	7.83e-07	1297	99	16	33545068
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	JCAD CALU EXPH5 PFKFB2 SIK3 PPP1CA SH3PXD2A ELMO2 TESK2 LPP PPIP5K2 CAMSAP1 DNMT1	1.04e-06	861	99	13	36931259
Pubmed	14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking.	ACLY MCM3 PFKFB2 CRKL PPP1CA EEF2 DNMT1	1.10e-06	186	99	7	14744259
Pubmed	Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation.	PPP1CA PPP1CB PPP1CC	1.24e-06	8	99	3	16262633
Pubmed	The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.	PPP1CA PPP1CB PPP1CC	1.24e-06	8	99	3	21930935
Pubmed	A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat.	PPP1CA PPP1CB PPP1CC	1.24e-06	8	99	3	12036313
Pubmed	Identification and characterization of a novel human PP1 phosphatase complex.	ASH2L PPP1CA PPP1CB PPP1CC	1.83e-06	31	99	4	20516061
Pubmed	RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits.	PPP1CA PPP1CB PPP1CC	1.86e-06	9	99	3	20926688
Pubmed	Consensus PP1 binding motifs regulate transcriptional corepression and alternative RNA splicing activities of the steroid receptor coregulators, p54nrb and PSF.	PPP1CA PPP1CB PPP1CC	1.86e-06	9	99	3	21566083
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RPN1 POLR2C CYP51A1 DDX42 LANCL1 MCM3 SIK3 PPP1CA PPP1CB PPP1CC BPTF EEF2 PPIP5K2 CNOT1	2.38e-06	1082	99	14	38697112
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ADAP1 RPN1 SPEF2 DDX42 PPP1CA PPP1CB PPP1CC BPTF STK11 EEF2 SH3PXD2A GNA13 LMLN LSM14A MAPK6 PPIP5K2	3.09e-06	1442	99	16	35575683
Pubmed	ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.	PPP1CA PPP1CB PPP1CC LSM14A	4.23e-06	38	99	4	30629181
Pubmed	PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.	PPP1CA PPP1CB PPP1CC	4.83e-06	12	99	3	10830164
Pubmed	Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.	BHLHE41 PPP1CA PPP1CB PPP1CC	5.22e-06	40	99	4	23555304
Pubmed	Defining the membrane proteome of NK cells.	HGF ABCA2 RPN1 CALU ACLY CYP51A1 DDX42 MCM3 PARP14 EEF2 GNA13 CHST12 CNOT1 GPAT4	5.72e-06	1168	99	14	19946888
Pubmed	Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.	PPP1CA PPP1CB PPP1CC	7.96e-06	14	99	3	16048649
Pubmed	The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases.	PPP1CB PPP1CC	8.02e-06	2	99	2	2544298
Pubmed	Isoform diversity of phosphorylase kinase alpha and beta subunits generated by alternative RNA splicing.	PHKA1 PHKB	8.02e-06	2	99	2	1874721
Pubmed	Tyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL.	CRKL DCBLD2	8.02e-06	2	99	2	23770091
Pubmed	Protein phosphatase 1 abrogates IRF7-mediated type I IFN response in antiviral immunity.	PPP1CA PPP1CB	8.02e-06	2	99	2	27469204
Pubmed	Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene.	PPP1CA PPP1CC	8.02e-06	2	99	2	9882500
Pubmed	Protein phosphatase 1-dependent transcriptional programs for long-term memory and plasticity.	PPP1CB PPP1CC	8.02e-06	2	99	2	20592054
Pubmed	Decline in corepressor CNOT1 in the pregnant myometrium near term impairs progesterone receptor function and increases contractile gene expression.	PGR CNOT1	8.02e-06	2	99	2	38897566
Pubmed	PP-1α and PP-1γ display antagonism and differential roles in tumorigenicity of lung cancer cells.	PPP1CA PPP1CC	8.02e-06	2	99	2	23176181
Pubmed	Unresponsiveness of platelets lacking both Galpha(q) and Galpha(13). Implications for collagen-induced platelet activation.	GNA13 GNAQ	8.02e-06	2	99	2	15326177
Pubmed	Anti-glycoprotein VI treatment severely compromises hemostasis in mice with reduced alpha2beta1 levels or concomitant aspirin therapy.	GNA13 GNAQ	8.02e-06	2	99	2	15505105
Pubmed	High-throughput mapping of a dynamic signaling network in mammalian cells.	RHOD PBK ARHGEF11 ASH2L PPP1CA PPP1CB GNA13	9.98e-06	260	99	7	15761153
Pubmed	A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis.	PPP1CA PPP1CB PPP1CC CDC34	1.09e-05	48	99	4	17274640
Pubmed	SIK2 orchestrates actin-dependent host response upon Salmonella infection.	CPM PPP1CA PPP1CB PPP1CC	1.29e-05	50	99	4	33947818
Pubmed	Regulation of HIV-1 transcription by protein phosphatase 1.	PPP1CA PPP1CB PPP1CC	1.48e-05	17	99	3	17266553
Pubmed	[Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].	PPP1CA PPP1CB PPP1CC	1.48e-05	17	99	3	21351466
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MCM3 GRIK3 SIK3 ARHGEF11 PPP1CA PPP1CB PPP1CC EEF2 NETO1 CAMSAP1 CNOT1 DNMT1	1.92e-05	963	99	12	28671696
Pubmed	A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.	RPN1 CALU MCM3 PPP1CB PPP1CC	2.29e-05	118	99	5	27377895
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	ASH2L PPP1CA PPP1CB PPP1CC BPTF	2.38e-05	119	99	5	23508102
Pubmed	LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia.	SIK3 STK11	2.40e-05	3	99	2	29526696
Pubmed	Expression of GTP-binding protein alpha subunits in human thymocytes.	GNA13 GNAQ	2.40e-05	3	99	2	7791744
Pubmed	Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network.	PPP1CA PPP1CC	2.40e-05	3	99	2	19074462
Pubmed	PAI1: a novel PP1-interacting protein that mediates human plasma's anti-apoptotic effect in endothelial cells.	PPP1CA PPP1CB	2.40e-05	3	99	2	28296156
Pubmed	The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation.	PPP1CA PPP1CC	2.40e-05	3	99	2	12138106
Pubmed	Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.	PPP1CA PPP1CC	2.40e-05	3	99	2	11739654
Pubmed	Identification of Galpha13 as one of the G-proteins that couple to human platelet thromboxane A2 receptors.	GNA13 GNAQ	2.40e-05	3	99	2	10318854
Pubmed	Assignment of human genes for phosphorylase kinase subunits alpha (PHKA) to Xq12-q13 and beta (PHKB) to 16q12-q13.	PHKA1 PHKB	2.40e-05	3	99	2	2757032
Pubmed	Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure.	PHKA1 PHKB	2.40e-05	3	99	2	10487978
Pubmed	Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity.	HTT DNMT1	2.40e-05	3	99	2	27516062
Pubmed	Uterine Gαq/11 signaling, in a progesterone-dependent manner, critically regulates the acquisition of uterine receptivity in the female mouse.	PGR GNAQ	2.40e-05	3	99	2	31091422
Pubmed	A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho.	ARHGEF11 GNA13	2.40e-05	3	99	2	10026210
Pubmed	Characterization of protein phosphatases in mouse oocytes.	PPP1CA PPP1CC	2.40e-05	3	99	2	9882488
Pubmed	Gαs directly drives PDZ-RhoGEF signaling to Cdc42.	ARHGEF11 GNA13	2.40e-05	3	99	2	33023908
Pubmed	The PP1 binding code: a molecular-lego strategy that governs specificity.	PPP1CA PPP1CB	2.40e-05	3	99	2	22360570
Pubmed	Holocarboxylase synthetase synergizes with methyl CpG binding protein 2 and DNA methyltransferase 1 in the transcriptional repression of long-terminal repeats.	HLCS DNMT1	2.40e-05	3	99	2	23624957
Pubmed	Dynamic multi-site phosphorylation by Fyn and Abl drives the interaction between CRKL and the novel scaffolding receptors DCBLD1 and DCBLD2.	CRKL DCBLD2	2.40e-05	3	99	2	29025973
Pubmed	NOM1 targets protein phosphatase I to the nucleolus.	PPP1CA PPP1CC	2.40e-05	3	99	2	17965019
Pubmed	Glucoamylase-like domains in the alpha- and beta-subunits of phosphorylase kinase.	PHKA1 PHKB	2.40e-05	3	99	2	12876330
Pubmed	DNMT1 is regulated by ATP-citrate lyase and maintains methylation patterns during adipocyte differentiation.	ACLY DNMT1	2.40e-05	3	99	2	23897429
Pubmed	An LKB1-SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation.	SIK3 STK11	2.40e-05	3	99	2	31350327
Pubmed	The AMPK-Related Kinases SIK1 and SIK3 Mediate Key Tumor-Suppressive Effects of LKB1 in NSCLC.	SIK3 STK11	2.40e-05	3	99	2	31350328
Pubmed	Gβγ signaling to the chemotactic effector P-REX1 and mammalian cell migration is directly regulated by Gαq and Gα13 proteins.	GNA13 GNAQ	2.40e-05	3	99	2	30446620
Pubmed	Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1.	PPP1CA PPP1CC	2.40e-05	3	99	2	11588169
Pubmed	Smyd1 Orchestrates Early Heart Development Through Positive and Negative Gene Regulation.	ASH2L NKX2-5	2.40e-05	3	99	2	33869215
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	ABCA2 RPN1 ACLY POLR2C PBK LANCL1 MCM3 ASH2L CRKL PPP1CA PPP1CC EEF2 LSM14A CDC34	2.54e-05	1335	99	14	29229926
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	ACLY DDX42 MCM3 PFKFB2 PPP1CC PHKB EEF2 LSM14A MAPK6	2.88e-05	551	99	9	34728620
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	JCAD HLCS MCM3 SIK3 ARHGEF11 CRKL PHKB ELMO2 PPIP5K2 CAMSAP1 CNOT1	3.21e-05	853	99	11	28718761
Pubmed	TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis.	RPN1 PPP1CA PPP1CB EEF2	4.13e-05	67	99	4	35670107
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	JCAD LEMD3 CALU POLR2C PPP1CA PPP1CB PPP1CC PHKA1 PHKB LPP CNOT1 DNMT1	4.42e-05	1049	99	12	27880917
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	BHLHE41 RPN1 MCM3 PPP1CA PPP1CC EEF2 NFATC2 NKX2-5 LSM14A	4.46e-05	583	99	9	29844126
Interaction	PPP1R2C interactions	PPP1CA PPP1CB PPP1CC	4.58e-07	4	99	3	int:PPP1R2C
Interaction	PHACTR3 interactions	PPP1CA PPP1CB PPP1CC LSM14A MAPK6	9.94e-07	37	99	5	int:PHACTR3
Interaction	CSRNP2 interactions	PPP1CA PPP1CB PPP1CC	1.14e-06	5	99	3	int:CSRNP2
Interaction	SFRP5 interactions	PPP1CA PPP1CB PPP1CC	2.28e-06	6	99	3	int:SFRP5
Interaction	SFRP1 interactions	PPP1CA PPP1CB PPP1CC DNMT1	6.40e-06	25	99	4	int:SFRP1
Interaction	LBR interactions	RHOD RPN1 PPP1CA PPP1CB PPP1CC EEF2 NKX2-5 LSM14A CDC34	1.90e-05	304	99	9	int:LBR
Interaction	PPP1R3C interactions	PPP1CA PPP1CB PPP1CC PHKB	2.01e-05	33	99	4	int:PPP1R3C
Interaction	GSK3B interactions	BHLHE41 ADAP1 ACLY MCM3 ARHGEF11 PPP1CA PPP1CB PPP1CC STK11 EEF2 NFATC2 LPP EDEM1 CAMSAP1 DNMT1	2.12e-05	868	99	15	int:GSK3B
Interaction	DELEC1 interactions	BHLHE41 PPP1CA PPP1CB PPP1CC	2.27e-05	34	99	4	int:DELEC1
Interaction	PPP1R2B interactions	PPP1CA PPP1CB PPP1CC	4.02e-05	14	99	3	int:PPP1R2B
Interaction	CDKN2A interactions	HGF RHOD ACLY GALNT12 PPP1CB PPP1CC STK11 EEF2 MAPK6	4.05e-05	335	99	9	int:CDKN2A
Interaction	RORC interactions	BHLHE41 PPP1CA PPP1CB PPP1CC	6.99e-05	45	99	4	int:RORC
Interaction	CALM2 interactions	RHOD CAMK1 PHKA1 PHKB STK11 SCO1 NKX2-5	7.08e-05	206	99	7	int:CALM2
Interaction	LINC02915 interactions	CRKL GUK1	7.14e-05	3	99	2	int:LINC02915
Interaction	ADISSP interactions	PPP1CA PPP1CB PPP1CC PHKB	7.63e-05	46	99	4	int:ADISSP
Interaction	RDX interactions	CALU PPP1CB PHKA1 EEF2 GNA13 LPP SCO1 SLC39A14	7.96e-05	284	99	8	int:RDX
Interaction	WDR82 interactions	JCAD DDX42 ASH2L PPP1CA PPP1CB PPP1CC HTT	8.73e-05	213	99	7	int:WDR82
Interaction	HSPA4 interactions	EXPH5 CYP51A1 ASH2L PGR PPP1CA PPP1CB PPP1CC SCO1 MAPK6 CDC34 HTT DNMT1	1.04e-04	667	99	12	int:HSPA4
Interaction	PPP1R3B interactions	PPP1CA PPP1CB PPP1CC	1.05e-04	19	99	3	int:PPP1R3B
Interaction	PLCL2 interactions	PPP1CA PPP1CB PPP1CC	1.05e-04	19	99	3	int:PLCL2
Interaction	YWHAQ interactions	JCAD CALU EXPH5 MCM3 HMGCS2 PFKFB2 SIK3 PPP1CA EEF2 NFATC2 SH3PXD2A TESK2 PPIP5K2 CAMSAP1 HTT DNMT1	1.05e-04	1118	99	16	int:YWHAQ
Interaction	NUAK1 interactions	MCM3 PPP1CB PPP1CC ELMO2 LSM14A	1.11e-04	96	99	5	int:NUAK1
Interaction	CANX interactions	ABCA2 RHOD RPN1 LEMD3 GAL3ST1 CALU CYP51A1 LANCL1 CAMK1 EEF2 TAS1R2 CHST12 FUCA2 EDEM1 CAMSAP1 CDC34 GPAT4	1.29e-04	1261	99	17	int:CANX
Interaction	CSRNP1 interactions	PPP1CA PPP1CB PPP1CC	1.43e-04	21	99	3	int:CSRNP1
Interaction	PDRG1 interactions	POLR2C PPP1CA PPP1CB PPP1CC CNOT1	2.02e-04	109	99	5	int:PDRG1
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP1CA PPP1CB PPP1CC	1.02e-05	13	61	3	693
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 GAL3ST1 CYP51A1 CPM KNDC1 CNTN2	2.84e-07	196	99	7	f068ce40bf35021baf1468ae9ce30a92162eb14d
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PBK TOGARAM1 PHKB FAM228B ZSCAN22 ATP4A	3.01e-06	179	99	6	4166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	JCAD CALU BPTF SH3PXD2A LPP CMAHP	4.24e-06	190	99	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	15\|World / Age, Tissue, Lineage and Cell class	CFAP276 CAMK1D NBEAL1 EXPH5 GALNT12 EEF2	4.64e-06	193	99	6	a8ad0de955494d6f5929dc44ba46627d06d95453
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABCA2 ADAP1 GAL3ST1 LANCL1 SIK3 CNTN2	4.78e-06	194	99	6	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	Control-Myeloid-MoAM4\|Myeloid / Condition, Lineage and Cell class	HGF CAMK1D TRPM2 CAMK1 NFATC2 DNMT1	4.78e-06	194	99	6	7ab808dd1876b0eec2831caa16d04fd859b1dc50
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 CYP51A1 CPM KNDC1 CNTN2	5.22e-06	197	99	6	7b12f9d4ad1e84df58e86591a491c84d4f36eac5
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 GAL3ST1 CPM KNDC1 CNTN2	5.37e-06	198	99	6	a183afe4c2034323f77abfa080f359d67da35e8f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 CYP51A1 CPM KNDC1 CNTN2	5.37e-06	198	99	6	97ae237f955fd5fbd01d06aafe89ef9e6f777a9a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 GAL3ST1 CPM KNDC1 CNTN2	5.53e-06	199	99	6	67d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 GAL3ST1 CPM KNDC1 CNTN2	5.69e-06	200	99	6	0e85c90719d9ec51a566e230c9dd2909d8df1f52
ToppCell	Severe-Developping_Plasmablast\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RNASEH2A RPN1 CALU PBK MCM3 DNMT1	5.69e-06	200	99	6	6d0cd00e52568d23597cc2a4059bd967d7d2dab5
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 GAL3ST1 CPM KNDC1 CNTN2	5.69e-06	200	99	6	e5b4821fff40566c4a7dc3f74a14e27eb06b165d
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHKA1 DNAH17 ABCD4 C3AR1 MAPK6	3.48e-05	166	99	5	13027ae342994db4540e64eb910df1f42b160931
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHKA1 DNAH17 ABCD4 C3AR1 MAPK6	3.48e-05	166	99	5	b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A5 HMGCS2 CAMK1 ARHGEF11 C3AR1	4.01e-05	171	99	5	a474aaed3ca4cacb0ab565c35f25d92a10f531b7
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF9 RTN4RL1 GALNT12 HMGCS2 CMAHP	4.60e-05	176	99	5	d4075796c38b775fe721abb47426e662a0d415e3
ToppCell	droplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A EXPH5 YY2 CRKL PGR	4.60e-05	176	99	5	533d544852038c0612aacf87f4b1c88ff7aace82
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SEMA7A CYP51A1 CRKL GNA13 DNAH17	4.98e-05	179	99	5	42f3c040f504a91cc69292d39d22b5715c12526f
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA7A CYP51A1 CRKL GNA13 DNAH17	4.98e-05	179	99	5	063c05753ef1b4a18bc1ebbcae62c8cd25d11070
ToppCell	COPD-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	SEMA7A TRPM2 MMP23B PFKFB2 COL24A1	4.98e-05	179	99	5	29b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF9 RTN4RL1 HMGCS2 SLC39A14 CMAHP	5.12e-05	180	99	5	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF9 RTN4RL1 HMGCS2 SLC39A14 CMAHP	5.12e-05	180	99	5	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	RNASEH2A NBEAL1 FAM228B ABCD4 HTT	5.68e-05	184	99	5	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RTN4RL1 HMGCS2 NFATC2 SLC39A14 ATP4A	5.82e-05	185	99	5	1d874608aa2062024323512f68889219471b2f00
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD CALU GNA13 LPP SLC39A14	5.82e-05	185	99	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 CFAP276 SPEF2 PGR KNDC1	5.98e-05	186	99	5	02fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell	PBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BHLHE41 RPN1 CALU COL24A1 EDEM1	6.77e-05	191	99	5	dd1d38a531a272a746c16807688013d29cab823a
ToppCell	NS-critical-d_0-4-Lymphoid-NK\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HGF CYP51A1 HLCS CAMK1 SLC39A14	7.11e-05	193	99	5	1b29525c5936d1b779253b8c20f059fa091c6127
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF9 PBK MCM3 MAPK6 DNMT1	7.29e-05	194	99	5	effd38e51062b225ecabc7e1c50154e65495d559
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	BHLHE41 CYP4B1 PARP14 ARHGAP27 PPIP5K2	7.29e-05	194	99	5	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	BHLHE41 CYP4B1 PARP14 ARHGAP27 PPIP5K2	7.29e-05	194	99	5	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	Control-Myeloid-MoAM4\|Control / Condition, Lineage and Cell class	HGF CAMK1D TRPM2 CAMK1 DNMT1	7.47e-05	195	99	5	211a736acbe875bd3c1942c62aaacc9b170ece6d
ToppCell	343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HGF TRPM2 CAMK1 NFATC2 C3AR1	7.47e-05	195	99	5	67b05a0cd2ca9924eca81a92cc6330eecb9d963c
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALU PPP1CB EEF2 LPP SLC39A14	7.65e-05	196	99	5	66d76249bd2770cdddff2c1fe59a016e95da2124
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRPM2 SIK3 GNA13 DNAH17 EDEM1	7.65e-05	196	99	5	01cea0bb0b938d0986fd2ddae06597b8af1768ee
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALU PPP1CB EEF2 LPP SLC39A14	7.65e-05	196	99	5	9bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 CYP51A1 SIK3 KNDC1 CNTN2	8.03e-05	198	99	5	a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCell	B_cell_maturation-CD34+_pro-B\|B_cell_maturation / Lineage and Cell class	RNASEH2A PBK MCM3 GNAQ DNMT1	8.03e-05	198	99	5	5737606e5e3dc56f11fdf70166caf4ba4a81bc9d
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 CPM KNDC1 CNTN2	8.03e-05	198	99	5	43a2ce64fa309bac89a44ea320e87ae2cc39f782
ToppCell	remission-NK\|World / disease stage, cell group and cell class	MMP23B PPP1CA NFATC2 GUK1 CHST12	8.03e-05	198	99	5	383ed78164ad37826100d3de6c3cc14f62e01813
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 GAL3ST1 KNDC1 CNTN2	8.03e-05	198	99	5	27f0654fb0857e93f030e1a4b1c307b31576bbcd
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 ADAP1 GAL3ST1 KNDC1 CNTN2	8.03e-05	198	99	5	fef9a4c96450078527b94d25e681410e4ea01b13
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MMP23B PPP1CA NFATC2 GUK1 CHST12	8.22e-05	199	99	5	fd3706f256e33cf348774bea0ba0df6d41fd96e3
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MMP23B PPP1CA NFATC2 GUK1 CHST12	8.22e-05	199	99	5	252f0084fa17770f4c34e21066519d7f7cad75d9
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MMP23B PPP1CA NFATC2 GUK1 CHST12	8.22e-05	199	99	5	e981b159841222a6838effff1059c683c20ecf5b
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-NK_cell\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MMP23B PPP1CA NFATC2 GUK1 CHST12	8.22e-05	199	99	5	8cdd5aa30a8112b77f5d02b40c45b63f541e1476
ToppCell	COVID-19_Convalescent-Lymphoid_T/NK-NK\|COVID-19_Convalescent / Disease group, lineage and cell class	MMP23B PPP1CA NFATC2 GUK1 CHST12	8.22e-05	199	99	5	9809d996a2c3f5384707646a3929e1d6b85dcdc2
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-NK_cell\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MMP23B PPP1CA NFATC2 GUK1 CHST12	8.22e-05	199	99	5	a2ac6af5e8e13e7edd3302ebdb175a3902bfb2bc
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	MMP23B PPP1CA NFATC2 GUK1 CHST12	8.22e-05	199	99	5	899642ff6bb6c1612f14a9a049b4344ae694752a
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BHLHE41 SLAMF9 TRPM2 CPM C3AR1	8.22e-05	199	99	5	f987f48970aec46156b80656e49b9f3604f3758c
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-NK\|COVID-19_Convalescent / Disease, condition lineage and cell class	MMP23B PPP1CA NFATC2 GUK1 CHST12	8.41e-05	200	99	5	50d844683dcfe35e59fffa0c23f1532d692d0c17
ToppCell	Severe-Developping_Plasmablast\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RNASEH2A RPN1 CALU PBK MCM3	8.41e-05	200	99	5	80639e0d2ddaae36ac7634a4f03e8809af7316e3
Drug	Metrizamide [31112-62-6]; Down 200; 5uM; MCF7; HT_HG-U133A	BHLHE41 HGF SEMA7A TRPM2 HLCS ARHGEF11 DNAH17 C3AR1	2.21e-06	195	99	8	4156_DN
Disease	lymphocyte count	IPPK JCAD ADAP1 EXPH5 SPEF2 ARHGEF11 PPP1CC STK11 NFATC2 DNAH17 LPP NKX2-5 GNAQ PPIP5K2 HTT DNMT1	2.85e-05	1464	99	16	EFO_0004587
Disease	Glycogen phosphorylase kinase deficiency	PHKA1 PHKB	6.66e-05	4	99	2	cv:C0268147
Disease	white matter integrity	NBEAL1 GAL3ST1 SH3PXD2A LPP ARHGAP27	7.89e-05	130	99	5	EFO_0004641
Disease	basophil count, eosinophil count	RPN1 SPEF2 SIK3 BPTF NFATC2 LPP	1.66e-04	241	99	6	EFO_0004842, EFO_0005090
Disease	descending aortic diameter	JCAD SIK3 ADAMTS7 NKX2-5	2.24e-04	88	99	4	EFO_0021788
Disease	age of onset of anorexia nervosa	CMAHP DCBLD2	2.31e-04	7	99	2	OBA_2050099
Disease	neuroimaging measurement	NBEAL1 GAL3ST1 GALNT12 PFKFB2 ARHGEF11 COL24A1 SH3PXD2A GNA13 ARHGAP27 SLC39A14 MAPK6 HTT	2.45e-04	1069	99	12	EFO_0004346
Disease	renin measurement	NBEAL1 CNTN2	3.08e-04	8	99	2	EFO_0010616
Disease	white matter microstructure measurement	HGF NBEAL1 GAL3ST1 BPTF SH3PXD2A GNA13 ARHGAP27	3.50e-04	390	99	7	EFO_0005674
Disease	Neoplasm Invasiveness	HGF CALU HMGCS2 EEF2 DNMT1	3.98e-04	184	99	5	C0027626
Disease	Carcinoma, Granular Cell	PGR STK11 EEF2 DNMT1	6.40e-04	116	99	4	C0205644
Disease	Adenocarcinoma, Tubular	PGR STK11 EEF2 DNMT1	6.40e-04	116	99	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	PGR STK11 EEF2 DNMT1	6.40e-04	116	99	4	C0205642
Disease	Carcinoma, Cribriform	PGR STK11 EEF2 DNMT1	6.40e-04	116	99	4	C0205643
Disease	Adenocarcinoma, Basal Cell	PGR STK11 EEF2 DNMT1	6.40e-04	116	99	4	C0205641
Disease	Adenocarcinoma	PGR STK11 EEF2 DNMT1	6.40e-04	116	99	4	C0001418
Disease	Manganese Poisoning	SLC39A14 HTT	9.88e-04	14	99	2	C0677050
Disease	allergic rhinitis	SPEF2 SIK3 NFATC2 LPP	1.07e-03	133	99	4	EFO_0005854
Disease	hypertension, white matter hyperintensity measurement	NBEAL1 SH3PXD2A GNA13	1.20e-03	62	99	3	EFO_0000537, EFO_0005665
Disease	Glycogen storage disease	PHKA1 PHKB	1.47e-03	17	99	2	cv:C0017919
Disease	dyslexia	CYP51A1 LPP GNAQ HTT	2.20e-03	162	99	4	EFO_0005424
Disease	total iron binding capacity	GRIK3 LMLN CMAHP	2.32e-03	78	99	3	EFO_0006334
Disease	frailty measurement	MAPK6 HTT	2.69e-03	23	99	2	EFO_0009885
Disease	Liver Failure, Acute	HGF SCO1	2.93e-03	24	99	2	C0162557
Disease	Carcinoma, Pancreatic Ductal	STK11 DNMT1	2.93e-03	24	99	2	C0887833

Protein segments in the cluster

Peptide	Gene	Start	Entry
GNAFIEHYDPKEYDP	FAM228B	121	P0C875
YRPLDPDNYDKDLSF	PFKFB2	201	O60825
YSDYIKGSNLDAPEP	DNMT1	976	P26358
GLEKYLYPAAAAAPF	BHLHE41	371	Q9C0J9
YGYKTEPVPDQDELD	CPA1	316	P15085
IIGPEEDYDPGYFNN	ARHGEF11	291	O15085
YVLDDPDPDDGFNYK	CALU	136	O43852
QEFIYPEKQEPYSAG	ADAP1	116	O75689
PEKQEPYSAGYREGF	ADAP1	121	O75689
YPLKEVYPDSGSADD	ABCD4	476	O14678
VDPNDAPDYYGVIKE	BPTF	2956	Q12830
SLDYPDFYGDPLENR	C3AR1	181	Q16581
YGRDNIPEDLRDPFY	CAMSAP1	51	Q5T5Y3
ELDLPGPVFVDDFYY	ADAMTS7	1051	Q9UKP4
FNKDGYRYILAEPDP	ASH2L	336	Q9UBL3
YYFDPEIPKDDLDFR	CFAP276	61	Q5T5A4
DNPYDVKELIPEFFY	NBEAL1	2146	Q6ZS30
GKQAPELPDYAPDYQ	RTN4RL1	371	Q86UN2
RYNFTPDPDFKDLGA	NETO1	151	Q8TDF5
IDGPYDEAFYQKLLD	IPPK	361	Q9H8X2
YFPEYDGPQRDAQAA	GNAQ	291	P50148
AAYLKDLGPEYEGIF	LEMD3	561	Q9Y2U8
SGPAYPDDVLDYGLK	NFATC2	56	Q13469
FPNPYADYNKSLAEG	LANCL1	6	O43813
PGPEGKLYSEDYDDN	PHKA1	621	P46020
AYDGFVQYIPFDDPR	JCAD	416	Q9P266
YFDELSGIPAEDLPY	LMLN	456	Q96KR4
KFASAENIPDLPYDY	HLCS	121	P50747
SEIDYPPFEKNFYNE	DDX42	206	Q86XP3
FYKPNLASEYPIVDG	HMGCS2	241	P54868
DQFALYKEGDPAPYK	GP6	141	Q9HCN6
YLDGDREKYLEDPAF	MAPK6	401	Q16659
LYDMENPPADEYFGR	LPP	401	Q93052
EIDPADKYVYPRGFQ	EXPH5	396	Q8NEV8
ADEEDPLGPNCYYDK	LSM14A	351	Q8ND56
LPERYPDKGFDDNYC	HGF	246	P14210
YFLDNLDKLGEPDYI	GNA13	176	Q14344
LYDFPGNDAEDLPFK	CRKL	131	P46109
AFYPRAYSDPDPAKD	NKX2-5	91	P52952
LLCGYPPFYDENDAK	CAMK1	211	Q14012
QPDAKDGDSYDPYDF	MCM3	696	P25205
DAEPKDDAYPLYSDF	PGR	366	P06401
FPPESNYLFLGDYVD	PPP1CA	81	P62136
PPEANYLFLGDYVDR	PPP1CB	81	P62140
PPGADDYSLKLFFEN	PARP14	236	Q460N5
IALQEEADYFGIPYP	KCTD18	86	Q6PI47
DDYDRLRPLFYPDAS	RHOD	76	O00212
KDNYPPSFKYEDFGP	FUCA2	91	Q9BTY2
FLQDPDRYYDPNGFN	GAL3ST1	196	Q99999
AFYLIENYPLDVGPE	HTT	2836	P42858
RNPRPGEENGKDYYF	GUK1	41	Q16774
NPDGFEAVKKPDCYY	CPM	126	P14384
YDPLDPGDSNFDRDY	DNAH17	476	Q9UFH2
PDETLNFIAPNKYEY	ELMO2	641	Q96JJ3
YPVAIKYDPQFGDAF	GPAT4	346	Q86UL3
ENYGRKEEPDHTYEP	COL6A5	2266	A8TX70
SPIEFLENAYEKYGP	CYP51A1	86	Q16850
NKGLTDYCFDYNPPD	GALNT12	451	Q8IXK2
DVYGDYRPLFDNPQD	ABCA2	1391	Q9BZC7
LDDFPIDFDKPGGHY	CNTN2	546	Q02246
PDEYEKRYSGAFPPQ	EDEM1	111	Q92611
GKDLDFYDFEPLPTL	KNDC1	16	Q76NI1
RGDPKAPDVYDFFLQ	CYP4B1	106	P13584
KYRCELLYEGPPDDE	EEF2	366	P13639
PEEGKEAGYADLDPY	DCBLD2	641	Q96PD2
PLDNKDTFYVNLYPD	GRIK3	141	Q13003
YRVYYSPGPKDEDED	SCO1	241	O75880
LIPEAFGFNPLEDYY	SLC39A14	206	Q15043
LNEKDYPPGYAFDVE	ATP4A	571	P20648
YVPADFVEYEKNNPG	PHKB	411	Q93100
LVAYKNPAFDDYPLG	LRRN4	721	Q8WUT4
FADYEKDPPQLDYTQ	SPEF2	1616	Q9C093
DLDTDYGSGYPNDPK	RNASEH2A	201	O75792
KDQEPLEFSYPGYLA	MMP23B	336	O75900
EDPHGKPYFYNPEDS	ARHGAP27	421	Q6ZUM4
DLLDYGPFRDVPAYS	RPN1	196	P04843
PPYAAPELFEGKEYD	SIK3	226	Q9Y2K2
GLYPFEGDNIYKLFE	STK11	251	Q15831
AYRPQDLPEDRYDKA	TEX45	251	Q8NA69
CGYPPFYDENDSKLF	CAMK1D	216	Q8IU85
DPNGKPERFYYNVES	POLR2C	221	P19387
PFGREAYPEEAYIAD	ACLY	241	P53396
DEDFNPFPGGYDYLV	CMAHP	376	Q9Y471
PFPGGYDYLVDFLDL	CMAHP	381	Q9Y471
YEADFVLFGYPKPEN	CHST12	396	Q9NRB3
EYDDPPGLREKAEYL	CNOT1	1841	A5YKK6
DLRKEGEFYPDATYP	COL24A1	446	Q17RW2
APAPDEGSDLFYDDY	CDC34	196	P49427
LKYEEPEYDIPAFGF	SH3PXD2A	551	Q5TCZ1
YDPPFYTAERKDAAA	TRPM2	1271	O94759
EGQAENPPDYSEYLK	YY2	201	O15391
YYFFREDNPDKNPEA	SEMA7A	241	O75326
FDDEAYYAALGTRPP	PBK	266	Q96KB5
DGPFYADPNYASEKP	SLAMF9	216	Q96A28
FPPESNYLFLGDYVD	PPP1CC	81	P36873
PAENSDFYLPGDYLL	TAS1R2	21	Q8TE23
DKFDLVDAYGTEPPY	ZSCAN22	246	P10073
EEDKNLPSGYGYRPA	PPIP5K2	901	O43314
YYLELEASGFPEDPL	TOGARAM1	321	Q9Y4F4
DPDYLPRTENFGLDY	TESK2	256	Q96S53
FTDIYGLPQYEKPDA	WWC3	391	Q9ULE0
DPGKREFYFDRDPDA	KCNF1	71	Q9H3M0