Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF597 TSHZ3 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 TRPS1 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ADNP ZNF529 ZNF284 ZNF404 ZNF585B RLF KMT2D ZNF37A ZNF41 TSHZ1 ZNF350 ZNF543 ZNF876P ZBTB11 ZNF679 ZNF98 PRDM15 NR1H4	2.53e-09	1412	133	31	GO:0000981
GeneOntologyMolecularFunction	zinc ion binding	TRIM49 ZMYND11 HDAC4 RCHY1 TRPS1 TRIM49C TRIM49D1 ZMYM2 CUL9 MARCHF7 TRIM43 ZNFX1 ZFAND5 TRIM43B USP5 TIMM9 TIMP2 TRIM63 ZFAND6 POLR1B ZMYM4 NR1H4	1.02e-07	891	133	22	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	ADCY10 TRIM49 ZMYND11 HDAC4 RCHY1 TRPS1 TRIM49C TRIM49D1 ZMYM2 CUL9 MARCHF7 TRIM43 ZNFX1 ZFAND5 ADNP TRIM43B NEK4 USP5 TIMM9 TIMP2 TRIM63 ZFAND6 POLR1B ZMYM4 NR1H4	2.67e-07	1189	133	25	GO:0046914
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF597 ZNF585A ZNF555 HDAC4 ZNF473 ZNF652 ZNF423 TRPS1 IKZF1 ZNF57 ZNF225 ZNF236 ADNP ZNF529 ZNF284 ZNF404 ZNF585B ZNF37A ZNF41 NCOA1 ZNF350 ZNF543 ZNF876P ZBTB11 ZNF679 ZNF98 PRDM15 NR1H4	2.95e-07	1459	133	28	GO:0000977
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	TRIM49 ATG16L1 ATG10 HDAC4 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 HDAC7 TRIM43B ERCC8 DZIP3 TRIM63	3.13e-07	512	133	16	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	TRIM49 ATG16L1 ATG10 HDAC4 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 HDAC7 TRIM43B ERCC8 DZIP3 TRIM63	5.22e-07	532	133	16	GO:0016755
GeneOntologyMolecularFunction	acyltransferase activity	TRIM49 ATG16L1 ATG10 HDAC4 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 HDAC7 TRIM43B ERCC8 KMT2C BRCA2 DZIP3 TRIM63 NCOA1	9.34e-07	775	133	19	GO:0016746
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18 NCOA1 NR1H4	1.73e-06	55	133	6	GO:0042974
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	TRIM49 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 TRIM43B DZIP3 TRIM63	4.02e-05	372	133	11	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	TRIM49 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 TRIM43B DZIP3 TRIM63	7.37e-05	398	133	11	GO:0061659
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF597 ZNF585A HDAC4 ZNF473 ZNF652 ZNF423 IKZF1 ZNF225 ZNF236 ZNF284 ZNF585B ZNF37A ZNF41 ZNF350 ZNF543 ZNF876P ZBTB11 ZNF679 ZNF98 PRDM15 NR1H4	7.39e-05	1244	133	21	GO:0000978
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	TRIM49 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 TRIM43B ERCC8 DZIP3 TRIM63	7.81e-05	473	133	12	GO:0004842
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF597 ZNF585A HDAC4 ZNF473 ZNF652 ZNF423 IKZF1 ZNF225 ZNF236 ZNF284 ZNF585B ZNF37A ZNF41 ZNF350 ZNF543 ZNF876P ZBTB11 ZNF679 ZNF98 PRDM15 NR1H4	1.00e-04	1271	133	21	GO:0000987
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18 FEM1C	2.20e-04	82	133	5	GO:1990756
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18 FEM1C	4.36e-04	95	133	5	GO:0140767
GeneOntologyMolecularFunction	methyltransferase activity	MRM1 NSUN7 KMT2C METTL13 PRDM10 KMT2D PRDM15	5.69e-04	213	133	7	GO:0008168
GeneOntologyMolecularFunction	transferase activity, transferring one-carbon groups	MRM1 NSUN7 KMT2C METTL13 PRDM10 KMT2D PRDM15	7.66e-04	224	133	7	GO:0016741
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2C KMT2D	1.20e-03	8	133	2	GO:0140945
GeneOntologyMolecularFunction	nuclear receptor binding	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18 NCOA1 NR1H4	1.60e-03	187	133	6	GO:0016922
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2C KMT2D	1.91e-03	10	133	2	GO:0140999
GeneOntologyBiologicalProcess	post-translational protein modification	TRIM49 ATG16L1 ATG10 HDAC4 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 FEM1C HDAC7 TRIM43B USP31 ERCC8 USP5 DZIP3 TRIM63	4.36e-05	1074	130	19	GO:0043687
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	TRIM49 ATG10 HDAC4 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 FEM1C HDAC7 TRIM43B ERCC8 USP5 DZIP3 TRIM63	4.66e-05	893	130	17	GO:0032446
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	TRIM49 ATG10 HDAC4 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 FEM1C HDAC7 TRIM43B USP31 ERCC8 USP5 DZIP3 TRIM63	6.35e-05	1009	130	18	GO:0070647
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	ZYG11A PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18 FEM1C	5.37e-07	47	134	6	GO:0031462
GeneOntologyCellularComponent	ubiquitin ligase complex	ZYG11A PRAMEF33 PCGF1 PRAMEF10 RCHY1 PRAMEF22 CUL9 PRAMEF18 FEM1C ERCC8 BRCA2	1.72e-05	352	134	11	GO:0000151
GeneOntologyCellularComponent	transferase complex	ZYG11A ATG16L1 PRAMEF33 PCGF1 PRAMEF10 RCHY1 PRAMEF22 TBC1D5 CUL9 ZNFX1 PRAMEF18 FEM1C CHML ERCC8 KMT2C KMT2D BRCA2 POLR1B	4.40e-05	963	134	18	GO:1990234
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	ZYG11A PRAMEF33 PRAMEF10 PRAMEF22 CUL9 PRAMEF18 FEM1C ERCC8	6.85e-05	212	134	8	GO:0031461
GeneOntologyCellularComponent	motile cilium	ADCY10 ATG16L1 PRAMEF10 PRAMEF22 PRAMEF18 TIMP2 DNAH17 CFAP44 DNAH11	4.81e-04	355	134	9	GO:0031514
Domain	zf-C2H2	ZNF597 BNC2 TSHZ3 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 TRPS1 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ADNP ZNF529 ZNF284 ZNF404 ZNF585B RLF PRDM10 ZNF37A ZNF41 ZNF350 ZNF543 ZBTB11 ZNF679 ZNF98 PRDM15 ZNF687	6.45e-16	693	131	30	PF00096
Domain	ZINC_FINGER_C2H2_2	ZNF597 BNC2 TSHZ3 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 TRPS1 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ADNP ZNF529 ZNF284 ZNF404 ZNF585B RLF PRDM10 ZNF37A ZNF41 TSHZ1 ZNF350 ZNF543 ZBTB11 ZNF679 ZNF98 PRDM15 ZNF687	1.72e-15	775	131	31	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF597 BNC2 TSHZ3 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 TRPS1 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ADNP ZNF529 ZNF284 ZNF404 ZNF585B RLF PRDM10 ZNF37A ZNF41 TSHZ1 ZNF350 ZNF543 ZBTB11 ZNF679 ZNF98 PRDM15 ZNF687	1.84e-15	777	131	31	PS00028
Domain	Znf_C2H2-like	ZNF597 BNC2 TSHZ3 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 TRPS1 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ADNP ZNF529 ZNF284 ZNF404 ZNF585B RLF PRDM10 ZNF37A ZNF41 TSHZ1 ZNF350 ZNF543 ZBTB11 ZNF679 ZNF98 PRDM15 ZNF687	3.57e-15	796	131	31	IPR015880
Domain	Znf_C2H2	ZNF597 BNC2 TSHZ3 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 TRPS1 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ADNP ZNF529 ZNF284 ZNF404 ZNF585B RLF PRDM10 ZNF37A ZNF41 TSHZ1 ZNF350 ZNF543 ZBTB11 ZNF679 ZNF98 PRDM15 ZNF687	4.85e-15	805	131	31	IPR007087
Domain	ZnF_C2H2	ZNF597 BNC2 TSHZ3 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 TRPS1 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ADNP ZNF529 ZNF284 ZNF404 ZNF585B RLF PRDM10 ZNF37A ZNF41 TSHZ1 ZNF350 ZNF543 ZBTB11 ZNF679 ZNF98 PRDM15 ZNF687	5.37e-15	808	131	31	SM00355
Domain	Znf_C2H2/integrase_DNA-bd	ZNF597 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ADNP ZNF529 ZNF284 ZNF404 ZNF585B RLF PRDM10 ZNF37A ZNF41 ZNF350 ZNF543 ZBTB11 ZNF679 ZNF98 PRDM15 ZNF687	2.95e-13	694	131	27	IPR013087
Domain	-	ZNF597 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ZNF529 ZNF284 ZNF404 ZNF585B RLF PRDM10 ZNF37A ZNF41 ZNF350 ZNF543 ZBTB11 ZNF679 ZNF98 PRDM15	8.44e-12	679	131	25	3.30.160.60
Domain	KRAB	ZNF597 ZNF585A ZNF555 ZNF473 ZNF57 ZNF225 ZNF529 ZNF284 ZNF404 ZNF585B ZNF37A ZNF41 ZNF350 ZNF543 ZNF679 ZNF98	4.46e-09	358	131	16	PS50805
Domain	KRAB	ZNF597 ZNF585A ZNF555 ZNF473 ZNF57 ZNF225 ZNF529 ZNF284 ZNF404 ZNF585B ZNF37A ZNF41 ZNF350 ZNF543 ZNF679 ZNF98	4.46e-09	358	131	16	PF01352
Domain	KRAB	ZNF597 ZNF585A ZNF555 ZNF473 ZNF57 ZNF225 ZNF529 ZNF284 ZNF404 ZNF585B ZNF37A ZNF41 ZNF350 ZNF543 ZNF679 ZNF98	6.85e-09	369	131	16	SM00349
Domain	KRAB	ZNF597 ZNF585A ZNF555 ZNF473 ZNF57 ZNF225 ZNF529 ZNF284 ZNF404 ZNF585B ZNF37A ZNF41 ZNF350 ZNF543 ZNF679 ZNF98	7.12e-09	370	131	16	IPR001909
Domain	Znf_RING	TRIM49 ZMYND11 PCGF1 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 MARCHF7 TRIM43 TRIM43B KMT2C KMT2D DZIP3 TRIM63	9.49e-09	326	131	15	IPR001841
Domain	RING	TRIM49 ZMYND11 PCGF1 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 TRIM43 TRIM43B KMT2C KMT2D DZIP3 TRIM63	3.14e-08	305	131	14	SM00184
Domain	zf-C2H2_6	ZNF597 ZNF555 ZNF473 ZNF652 ZNF423 ZBTB47 ZNF225 ZNF236 ZNF284 ZNF404 PRDM10 ZNF543 ZBTB11 ZNF98	4.52e-08	314	131	14	PF13912
Domain	-	TRIM49 ZMYND11 PCGF1 RCHY1 ZNF423 MKRN1 TRIM49C TRIM49D1 MARCHF7 TRIM43 TRIM43B KMT2C USP5 KMT2D DZIP3 TRIM63	1.05e-07	449	131	16	3.30.40.10
Domain	Znf_RING/FYVE/PHD	TRIM49 ZMYND11 PCGF1 RCHY1 ZNF423 MKRN1 TRIM49C TRIM49D1 MARCHF7 TRIM43 TRIM43B KMT2C USP5 KMT2D DZIP3 TRIM63	1.42e-07	459	131	16	IPR013083
Domain	ZF_RING_2	TRIM49 PCGF1 RCHY1 MKRN1 TRIM49C TRIM49D1 CUL9 TRIM43 TRIM43B KMT2C KMT2D DZIP3 TRIM63	1.81e-07	298	131	13	PS50089
Domain	ZF_RING_1	TRIM49 PCGF1 RCHY1 MKRN1 TRIM49C CUL9 TRIM43 TRIM43B KMT2D DZIP3 TRIM63	6.59e-06	291	131	11	PS00518
Domain	BBOX	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B TRIM63	8.86e-06	69	131	6	SM00336
Domain	-	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B TRIM63	1.05e-05	71	131	6	4.10.45.10
Domain	ZF_BBOX	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B TRIM63	2.09e-05	80	131	6	PS50119
Domain	Znf_B-box	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B TRIM63	2.24e-05	81	131	6	IPR000315
Domain	Butyrophylin	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B	1.32e-04	70	131	5	IPR003879
Domain	Teashirt_fam	TSHZ3 TSHZ1	1.46e-04	3	131	2	IPR027008
Domain	zf-B_box	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM63	1.51e-04	72	131	5	PF00643
Domain	Fumarylacetoacetase_C-rel	FAHD2B FAHD2A	2.90e-04	4	131	2	IPR011234
Domain	FAA_hydrolase	FAHD2B FAHD2A	2.90e-04	4	131	2	PF01557
Domain	-	FAHD2B FAHD2A	2.90e-04	4	131	2	3.90.850.10
Domain	Histone_deAcase_II_euk	HDAC4 HDAC7	2.90e-04	4	131	2	IPR017320
Domain	PRAME_family	PRAMEF10 PRAMEF22 PRAMEF18	3.01e-04	19	131	3	IPR026271
Domain	SPRY	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B	3.67e-04	87	131	5	SM00449
Domain	SET_dom	KMT2C PRDM10 KMT2D PRDM15	4.15e-04	50	131	4	IPR001214
Domain	SET	KMT2C PRDM10 KMT2D PRDM15	4.15e-04	50	131	4	PS50280
Domain	FYrich_C	KMT2C KMT2D	4.82e-04	5	131	2	IPR003889
Domain	FYrich_N	KMT2C KMT2D	4.82e-04	5	131	2	IPR003888
Domain	FYRC	KMT2C KMT2D	4.82e-04	5	131	2	SM00542
Domain	FYRN	KMT2C KMT2D	4.82e-04	5	131	2	SM00541
Domain	DUF3504	ZMYM2 ZMYM4	4.82e-04	5	131	2	IPR021893
Domain	DUF3504	ZMYM2 ZMYM4	4.82e-04	5	131	2	PF12012
Domain	FYRN	KMT2C KMT2D	4.82e-04	5	131	2	PF05964
Domain	FYRC	KMT2C KMT2D	4.82e-04	5	131	2	PF05965
Domain	FYRC	KMT2C KMT2D	4.82e-04	5	131	2	PS51543
Domain	FYRN	KMT2C KMT2D	4.82e-04	5	131	2	PS51542
Domain	SPRY	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B	5.24e-04	94	131	5	PF00622
Domain	SPRY_dom	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B	5.24e-04	94	131	5	IPR003877
Domain	B30.2/SPRY	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B	5.50e-04	95	131	5	IPR001870
Domain	B302_SPRY	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B	5.50e-04	95	131	5	PS50188
Domain	Znf_MYM	ZMYM2 ZMYM4	1.00e-03	7	131	2	IPR010507
Domain	ZF_A20	ZFAND5 ZFAND6	1.00e-03	7	131	2	PS51036
Domain	zf-A20	ZFAND5 ZFAND6	1.00e-03	7	131	2	PF01754
Domain	Znf_A20	ZFAND5 ZFAND6	1.00e-03	7	131	2	IPR002653
Domain	zf-FCS	ZMYM2 ZMYM4	1.00e-03	7	131	2	PF06467
Domain	ZnF_A20	ZFAND5 ZFAND6	1.00e-03	7	131	2	SM00259
Domain	zf-C3HC4	PCGF1 RCHY1 MKRN1 MARCHF7 TRIM43 DZIP3 TRIM63	1.01e-03	223	131	7	PF00097
Domain	Znf_RING_CS	PCGF1 MKRN1 CUL9 TRIM43 TRIM43B TRIM63	1.03e-03	163	131	6	IPR017907
Domain	TRASH_dom	ZMYM2 ZMYM4	1.33e-03	8	131	2	IPR011017
Domain	TRASH	ZMYM2 ZMYM4	1.33e-03	8	131	2	SM00746
Domain	ZF_AN1	ZFAND5 ZFAND6	1.33e-03	8	131	2	PS51039
Domain	ZnF_AN1	ZFAND5 ZFAND6	1.33e-03	8	131	2	SM00154
Domain	-	ZFAND5 ZFAND6	1.33e-03	8	131	2	4.10.1110.10
Domain	zf-AN1	ZFAND5 ZFAND6	1.33e-03	8	131	2	PF01428
Domain	Znf_AN1	ZFAND5 ZFAND6	1.33e-03	8	131	2	IPR000058
Domain	Znf_C3HC4_RING-type	PCGF1 RCHY1 MKRN1 MARCHF7 DZIP3 TRIM63	1.35e-03	172	131	6	IPR018957
Domain	Hist_deacetyl	HDAC4 HDAC7	2.58e-03	11	131	2	PF00850
Domain	-	HDAC4 HDAC7	2.58e-03	11	131	2	3.40.800.20
Domain	His_deacetylse_dom	HDAC4 HDAC7	2.58e-03	11	131	2	IPR023801
Domain	His_deacetylse	HDAC4 HDAC7	2.58e-03	11	131	2	IPR000286
Domain	SET	KMT2C KMT2D PRDM15	4.11e-03	46	131	3	SM00317
Domain	ConA-like_dom	TRIM49 NBEAL1 TRIM49C TRIM49D1 TRIM43 TRIM43B	4.50e-03	219	131	6	IPR013320
Domain	Post-SET_dom	KMT2C KMT2D	5.49e-03	16	131	2	IPR003616
Domain	PostSET	KMT2C KMT2D	5.49e-03	16	131	2	SM00508
Domain	POST_SET	KMT2C KMT2D	5.49e-03	16	131	2	PS50868
Pubmed	Interaction network of human early embryonic transcription factors.	TSHZ3 PCGF1 HDAC4 ZNF423 TRPS1 ZMYM2 RLF KMT2C KMT2D NCOA1 ZMYM4	1.61e-07	351	137	11	38297188
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM49 TRIM49C TRIM43 TRIM43B	3.04e-07	15	137	4	19703589
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TSHZ3 TRPS1 ZMYM2 ADNP KIF20B RLF KMT2D BRCA2 ZBTB11 ZMYM4 ZNF687	9.06e-07	418	137	11	34709266
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	IPO5 TSHZ3 ZMYND11 PCGF1 ZMYM2 ADNP KIF20B RLF ZBTB11 CABIN1 PRDM15 ZMYM4 TOP2B	9.27e-07	608	137	13	36089195
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18	1.06e-06	20	137	4	26694250
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18	1.60e-06	22	137	4	31729367
Pubmed	ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.	KMT2C KMT2D NR1H4	2.07e-06	7	137	3	19556342
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18	2.73e-06	25	137	4	37451217
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	TSHZ3 ZMYM2 ADNP ZMYM4 TOP2B ZNF687	3.50e-06	103	137	6	32744500
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18	4.38e-06	28	137	4	25089626
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18	5.83e-06	30	137	4	38786026
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF555 ZNF57 ZNF529 ZNF41 ZNF543 ZBTB11 ZNF98	8.01e-06	181	137	7	37372979
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18	1.10e-05	35	137	4	19389355
Pubmed	Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.	ZMYM2 ADNP RLF PRDM10 ZMYM4	1.14e-05	74	137	5	29795351
Pubmed	Bile acids: natural ligands for an orphan nuclear receptor.	NCOA1 NR1H4	1.54e-05	2	137	2	10334993
Pubmed	Identification of a nuclear receptor for bile acids.	NCOA1 NR1H4	1.54e-05	2	137	2	10334992
Pubmed	Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation.	NCOA1 NR1H4	1.54e-05	2	137	2	18391212
Pubmed	KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.	KMT2C KMT2D	1.54e-05	2	137	2	31924266
Pubmed	Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids.	NCOA1 NR1H4	1.54e-05	2	137	2	11136553
Pubmed	Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.	KMT2C KMT2D	1.54e-05	2	137	2	28967912
Pubmed	Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location.	OR4F4 OR4F17	1.54e-05	2	137	2	11689484
Pubmed	Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes.	OR4F4 OR4F17	1.54e-05	2	137	2	11689483
Pubmed	Selective dimerization of a C2H2 zinc finger subfamily.	TRPS1 IKZF1	1.54e-05	2	137	2	12620233
Pubmed	Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation.	HDAC4 HDAC7	1.54e-05	2	137	2	38657041
Pubmed	Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.	KMT2C KMT2D	1.54e-05	2	137	2	36601880
Pubmed	Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.	KMT2C KMT2D	1.54e-05	2	137	2	28483418
Pubmed	The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion.	NCOA1 NR1H4	1.54e-05	2	137	2	14684751
Pubmed	Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.	FAHD2B FAHD2A	1.54e-05	2	137	2	15774318
Pubmed	Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.	ZNF585A ZNF585B	1.54e-05	2	137	2	37668106
Pubmed	The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.	KMT2C KMT2D	1.54e-05	2	137	2	34156443
Pubmed	Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.	KMT2C KMT2D	1.54e-05	2	137	2	27280393
Pubmed	Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.	KMT2C KMT2D	1.54e-05	2	137	2	36869380
Pubmed	In vitro farnesoid X receptor ligand sensor assay using surface plasmon resonance and based on ligand-induced coactivator association.	NCOA1 NR1H4	1.54e-05	2	137	2	14698205
Pubmed	Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.	KMT2C KMT2D	1.54e-05	2	137	2	25346535
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	BNC2 ZMYND11 ZNF473 ZNF423 MKRN1 TRPS1 ZMYM2 ZNF236 PKHD1L1 NCOA1 EXOC2 ZNF679 ZNF687	1.98e-05	808	137	13	20412781
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	PCGF1 TRPS1 ZMYM2 ADNP KMT2D	2.00e-05	83	137	5	28794006
Pubmed	A molecular dissection of the repression circuitry of Ikaros.	HDAC4 IKZF1 HDAC7	2.11e-05	14	137	3	12015313
Pubmed	Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.	KMT2C KMT2D NCOA1	2.11e-05	14	137	3	12482968
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	PCGF1 ZNF585A MKRN1 TRPS1 IKZF1 ZFAND5 ZNF585B RLF KMT2C ZFAND6 NCOA1 ZNF687	2.57e-05	709	137	12	22988430
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	ADNP KMT2C USP5 KMT2D NCOA1 ZMYM4 TOP2B	2.82e-05	220	137	7	35785414
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF10 PRAMEF22 PRAMEF18	3.90e-05	17	137	3	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF10 PRAMEF22 PRAMEF18	3.90e-05	17	137	3	37781892
Pubmed	Identification of a signal-responsive nuclear export sequence in class II histone deacetylases.	HDAC4 HDAC7	4.61e-05	3	137	2	11509672
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2C KMT2D	4.61e-05	3	137	2	23932714
Pubmed	A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle.	FAHD2B FAHD2A	4.61e-05	3	137	2	38287013
Pubmed	Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms.	NCOA1 NR1H4	4.61e-05	3	137	2	20338915
Pubmed	Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.	KMT2C KMT2D	4.61e-05	3	137	2	22183980
Pubmed	The multi zinc-finger protein Trps1 acts as a regulator of histone deacetylation during mitosis.	HDAC4 TRPS1	4.61e-05	3	137	2	23892436
Pubmed	Characterization of the zinc finger proteins ZMYM2 and ZMYM4 as novel B-MYB binding proteins.	ZMYM2 ZMYM4	4.61e-05	3	137	2	32439918
Pubmed	HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.	KMT2C KMT2D	4.61e-05	3	137	2	21683083
Pubmed	Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development.	TSHZ3 TSHZ1	4.61e-05	3	137	2	16631416
Pubmed	Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction.	TSHZ3 TSHZ1	4.61e-05	3	137	2	19745106
Pubmed	Association of ATG10 rs1864183, ATG16L1 rs2241880 and miR-126 with esophageal cancer.	ATG16L1 ATG10	4.61e-05	3	137	2	38281293
Pubmed	Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.	KMT2C NR1H4	4.61e-05	3	137	2	21330447
Pubmed	Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding.	NCOA1 NR1H4	4.61e-05	3	137	2	30275017
Pubmed	Novel structural insights into class I and II histone deacetylases.	HDAC4 HDAC7	4.61e-05	3	137	2	19355988
Pubmed	Three putative murine Teashirt orthologues specify trunk structures in Drosophila in the same way as the Drosophila teashirt gene.	TSHZ3 TSHZ1	4.61e-05	3	137	2	14973285
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18	4.61e-05	50	137	4	31806660
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF10 PRAMEF22 PRAMEF18	4.67e-05	18	137	3	23894331
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF10 PRAMEF22 PRAMEF18	4.67e-05	18	137	3	39181896
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF10 PRAMEF22 PRAMEF18	4.67e-05	18	137	3	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF10 PRAMEF22 PRAMEF18	4.67e-05	18	137	3	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF10 PRAMEF22 PRAMEF18	4.67e-05	18	137	3	14675769
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	PRAMEF33 PRAMEF10 ZNF473 RCHY1 PRAMEF22 TRPS1 PRAMEF18 TIMM9	4.80e-05	326	137	8	17015433
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	ZMYM2 ADNP KMT2C KMT2D CABIN1 ZMYM4	5.48e-05	167	137	6	20362541
Pubmed	Identification of a genomic reservoir for new TRIM genes in primate genomes.	TRIM49 TRIM49C TRIM49D1	5.53e-05	19	137	3	22144910
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF10 PRAMEF22 PRAMEF18	5.53e-05	19	137	3	28604677
Pubmed	Tagging genes with cassette-exchange sites.	BNC2 HDAC4 ZNF423 RPS6KA1 KMT2C USP5 PEX19 ZMYM4	5.80e-05	335	137	8	15741177
Pubmed	Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.	PCGF1 RCHY1 MARCHF7 TRIM43 DZIP3	6.21e-05	105	137	5	22493164
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF225 ZNF284 ZNF404	6.49e-05	20	137	3	12743021
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF10 PRAMEF22 PRAMEF18	6.49e-05	20	137	3	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF10 PRAMEF22 PRAMEF18	6.49e-05	20	137	3	21425410
Pubmed	Lineage-specific biology revealed by a finished genome assembly of the mouse.	TRIM49 TRIM49C TRIM43 TRIM43B	6.72e-05	55	137	4	19468303
Pubmed	BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.	ZYG11A SHLD2 BNC2 BRCA2	7.74e-05	57	137	4	27433848
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2C KMT2D	9.19e-05	4	137	2	19221051
Pubmed	Cancer gene mutation frequencies for the U.S. population.	KMT2C KMT2D	9.19e-05	4	137	2	34645806
Pubmed	Structural studies on a protein-binding zinc-finger domain of Eos reveal both similarities and differences to classical zinc fingers.	TRPS1 IKZF1	9.19e-05	4	137	2	15491138
Pubmed	Tip60 is required for DNA interstrand cross-link repair in the Fanconi anemia pathway.	RCHY1 BRCA2	9.19e-05	4	137	2	18263878
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2C KMT2D	9.19e-05	4	137	2	28398509
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2C KMT2D	9.19e-05	4	137	2	23129768
Pubmed	EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.	ZMYND11 BRCA2	9.19e-05	4	137	2	14651845
Pubmed	Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes.	OR4F4 OR4F17	9.19e-05	4	137	2	9384599
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2C KMT2D	9.19e-05	4	137	2	24081332
Pubmed	Class IIa histone deacetylases: conducting development and differentiation.	HDAC4 HDAC7	9.19e-05	4	137	2	19412888
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF10 PRAMEF22 PRAMEF18	1.00e-04	23	137	3	19480014
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF10 PRAMEF22 PRAMEF18	1.29e-04	25	137	3	12620990
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF10 PRAMEF22 PRAMEF18	1.45e-04	26	137	3	18500982
Pubmed	Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1.	HDAC4 HDAC7	1.53e-04	5	137	2	15194749
Pubmed	A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.	HDAC4 HDAC7	1.53e-04	5	137	2	17379597
Pubmed	Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.	KMT2C KMT2D	1.53e-04	5	137	2	31127101
Pubmed	Refinement and discovery of new hotspots of copy-number variation associated with autism spectrum disorder.	ZMYND11 KMT2C	1.53e-04	5	137	2	23375656
Pubmed	Duplication and positive selection among hominin-specific PRAME genes.	PRAMEF22 PRAMEF18	1.53e-04	5	137	2	16159394
Pubmed	Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity.	HDAC4 HDAC7	1.53e-04	5	137	2	15280364
Pubmed	MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ.	KMT2C KMT2D	1.53e-04	5	137	2	32601106
Pubmed	A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.	KMT2C KMT2D	1.53e-04	5	137	2	26744420
Pubmed	Mutation specific functions of EGFR result in a mutation-specific downstream pathway activation.	IPO5 DGKA MAP4K5 EIF2B3	1.54e-04	68	137	4	25754235
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TRPS1 ZMYM2 CUL9 ADNP METTL13 PRDM10 KMT2D TSHZ1 CABIN1 PRDM15 ZMYM4 TOP2B	1.55e-04	857	137	12	25609649
Pubmed	The functional interactome landscape of the human histone deacetylase family.	IPO5 HDAC4 ZMYM2 IKZF1 ADNP HDAC7 ZNF687	1.56e-04	289	137	7	23752268
Pubmed	Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.	BNC2 ZMYM2 ZNF687	1.82e-04	28	137	3	29365100
Pubmed	A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.	HDAC4 HDAC7	2.29e-04	6	137	2	11279209
Interaction	HNF4A interactions	PCGF1 HDAC4 TRPS1 MUC19 ZMYM2 ADNP KMT2C KMT2D NCOA1 CABIN1 ZMYM4	1.37e-06	275	127	11	int:HNF4A
Interaction	IKZF4 interactions	NRG1 HDAC4 IKZF1 ZNF225 HDAC7	2.96e-06	36	127	5	int:IKZF4
Cytoband	1p36.21	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18	3.94e-05	63	137	4	1p36.21
Cytoband	7p21	ANKMY2 DNAH11	1.32e-04	6	137	2	7p21
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF597 BNC2 TSHZ3 ZNF585A ZNF555 ZNF473 ZNF652 ZNF423 TRPS1 ZBTB47 IKZF1 ZNF57 ZNF225 ZNF236 ZNF529 ZNF284 ZNF404 ZNF585B RLF PRDM10 ZNF37A ZNF41 TSHZ1 ZNF350 ZNF543 ZBTB11 ZNF679 ZNF98 PRDM15	1.19e-15	718	117	29	28
GeneFamily	Ring finger proteins	TRIM49 PCGF1 RCHY1 MKRN1 TRIM49C TRIM49D1 MARCHF7 TRIM43 TRIM43B DZIP3 TRIM63	1.72e-06	275	117	11	58
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM49 TRIM49C TRIM49D1 TRIM43 TRIM43B TRIM63	3.51e-05	95	117	6	59
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	TSHZ3 ADNP TSHZ1	1.14e-04	15	117	3	529
GeneFamily	Histone deacetylases, class IIA	HDAC4 HDAC7	2.47e-04	4	117	2	992
GeneFamily	PRAME family	PRAMEF10 PRAMEF22 PRAMEF18	4.84e-04	24	117	3	686
GeneFamily	Zinc fingers MYM-type	ZMYM2 ZMYM4	6.12e-04	6	117	2	86
GeneFamily	Zinc fingers AN1-type\|UPF1 like RNA helicases	ZFAND5 ZFAND6	1.13e-03	8	117	2	63
GeneFamily	Exocyst complex	EXOC6B EXOC2	1.45e-03	9	117	2	1055
GeneFamily	Olfactory receptors, family 52	OR52L1 OR52L2P OR52N4	3.92e-03	49	117	3	165
GeneFamily	Dyneins, axonemal	DNAH17 DNAH11	5.30e-03	17	117	2	536
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM10 PRDM15	5.30e-03	17	117	2	1197
GeneFamily	Zinc fingers MYND-type	ZMYND11 ANKMY2	8.05e-03	21	117	2	87
Coexpression	GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN	HDAC4 RPS6KA1 DGKA IKZF1 HDAC7 TIMM9 TIMP2 TOP2B IL6ST	3.70e-07	179	134	9	M6324
Coexpression	GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN	ZNF597 ZMYM2 DGKA KMT2C ZFAND6 ATP11C ZBTB11 TOP2B	6.29e-06	190	134	8	M8457
Coexpression	GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN	HDAC4 RPS6KA1 DGKA IKZF1 TIMM9 TIMP2 TOP2B	2.91e-05	171	134	7	M6321
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	NRG1 ZMYND11 HDAC4 ZMYM2 MARCHF7 ADNP KIF20B RLF NEK4 BRCA2 MAP4K5 NCOA1 ANKMY2 ZBTB11 ZMYM4	3.35e-05	856	134	15	M4500
Coexpression	BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF18 ZFAND6 NCOA1 ZMYM4	4.04e-05	180	134	7	MM612
ToppCell	MatrixFB-Fibroblast-C\|MatrixFB / shred on cell class and cell subclass (v4)	BNC2 ZNF423 PKHD1L1 IGFBP2 TIMP2 SORCS2 IL6ST	1.98e-06	190	136	7	d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCell	Parenchyma_Control_(B.)-Immune-TX-MoAM-4\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	C9orf85 ATG16L1 RICTOR ZNF57 KIF20B USP31 ZNF37A	2.51e-06	197	136	7	dc1c55e3aacc9d60d0f111c2f20f150ca296f011
ToppCell	severe_influenza-CD8+_T_naive\|severe_influenza / disease group, cell group and cell class (v2)	IPO5 FAHD2B RCHY1 DGKA ZNF57 ZNF225	1.02e-05	161	136	6	82196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERICH3 CCDC30 NSUN7 DZIP3 CFAP44 DNAH11	1.35e-05	169	136	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-2\|TCGA-Cervix / Sample_Type by Project: Shred V9	TRIM49 ADAM18 TRIM49C DEFB134 TRIM43B	1.40e-05	100	136	5	309e1600d21f3be97b48d183306b9115eb75e6a3
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	ZMYND11 HDAC4 ZBTB47 RICTOR ZNF37A DZIP3	1.75e-05	177	136	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	COVID-19_Convalescent-PLT_4\|World / Disease Group and Platelet Clusters	RCHY1 ZMYM2 MARCHF7 ZNF236 RLF PUS7L	2.32e-05	186	136	6	5954a1e3ffafb33f2a9bc87af3343f304fda4c92
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRG1 BNC2 ZNF423 PKHD1L1 CALCRL IL6ST	2.54e-05	189	136	6	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	NRG1 BNC2 ZNF423 PKHD1L1 CALCRL IL6ST	2.77e-05	192	136	6	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	ERICH3 CCDC30 IGFBP2 DZIP3 CFAP44 DNAH11	2.94e-05	194	136	6	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ERICH3 CCDC30 IGFBP2 DZIP3 CFAP44 DNAH11	2.94e-05	194	136	6	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	ERICH3 CCDC30 IGFBP2 DZIP3 CFAP44 DNAH11	3.11e-05	196	136	6	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERICH3 CCDC30 IGFBP2 DZIP3 CFAP44 DNAH11	3.20e-05	197	136	6	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERICH3 CCDC30 IGFBP2 DZIP3 CFAP44 DNAH11	3.20e-05	197	136	6	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERICH3 CCDC30 IGFBP2 DZIP3 CFAP44 DNAH11	3.20e-05	197	136	6	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERICH3 CCDC30 IGFBP2 DZIP3 CFAP44 DNAH11	3.20e-05	197	136	6	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_2-TTC12-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NRG1 OR4F5 OR52N4 POPDC3 TSHZ1 CALCRL	3.48e-05	200	136	6	945b8438e90ecf6768904de3dc7e32ea86348744
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_2-TTC12--L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NRG1 OR4F5 OR52N4 POPDC3 TSHZ1 CALCRL	3.48e-05	200	136	6	e5a6e47b040fe9566d532f0dfd6450c72ffbd95d
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_2-TTC12\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NRG1 OR4F5 OR52N4 POPDC3 TSHZ1 CALCRL	3.48e-05	200	136	6	448bf2fab5df0cfa41a306b1939bc83b31ff3acc
Disease	Kleefstra syndrome 2 (implicated_via_orthology)	KMT2C KMT2D	1.75e-05	2	124	2	DOID:0080598 (implicated_via_orthology)
Disease	esophagus squamous cell carcinoma (is_implicated_in)	RICTOR KMT2C KMT2D BRCA2	3.87e-05	45	124	4	DOID:3748 (is_implicated_in)
Disease	squamous cell carcinoma	BNC2 TRPS1 BRCA2 DNAH11	1.86e-04	67	124	4	EFO_0000707
Disease	Sezary Syndrome	RPS6KA1 KMT2C KMT2D	1.97e-04	27	124	3	C0036920
Disease	Malignant neoplasm of urinary bladder	HDAC4 KMT2C KMT2D BRCA2 TIMP2	3.31e-04	141	124	5	C0005684
Disease	cutaneous squamous cell carcinoma	BNC2 TRPS1 BRCA2	3.60e-04	33	124	3	EFO_1001927
Disease	Inflammatory Bowel Diseases	ATG16L1 MUC19 VNN1	4.30e-04	35	124	3	C0021390
Disease	susceptibility to influenza measurement	NRG1 SORCS2	7.71e-04	10	124	2	EFO_0803537
Disease	allergic disease	ADAD1 ZNF652 IKZF1 FEM1C HDAC7 ZMYM4	7.96e-04	258	124	6	MONDO_0005271
Disease	suntan	BNC2 TRPS1 EXOC2 PRDM15	9.53e-04	103	124	4	EFO_0004279
Disease	Male sterility	NSUN7 KMT2D NR1H4	1.09e-03	48	124	3	C0917731
Disease	Male infertility	NSUN7 KMT2D NR1H4	1.09e-03	48	124	3	C0021364
Disease	Subfertility, Male	NSUN7 KMT2D NR1H4	1.09e-03	48	124	3	C0848676
Disease	rheumatoid arthritis (implicated_via_orthology)	KMT2C IL6ST	1.12e-03	12	124	2	DOID:7148 (implicated_via_orthology)
Disease	actinic keratosis	BNC2 TRPS1	1.54e-03	14	124	2	EFO_0002496
Disease	diffuse large B-cell lymphoma	NCOA1 EXOC2	1.54e-03	14	124	2	EFO_0000403
Disease	C-reactive protein measurement	BNC2 RPS6KA1 TRPS1 RICTOR DEFB134 GPRC6A MAP4K5 DNAH17 EXOC6B POLR1B NR1H4 TOP2B DNAH11	1.72e-03	1206	124	13	EFO_0004458
Disease	IGF-1 measurement, IGFBP-3 measurement	MAP4K5 SORCS2	2.29e-03	17	124	2	EFO_0004626, EFO_0004627
Disease	a disintegrin and metalloproteinase with thrombospondin motifs 13 measurement	NRG1 PRDM15	2.29e-03	17	124	2	EFO_0008011
Disease	Fetal Alcohol Syndrome	RPS6KA1 ADNP	2.29e-03	17	124	2	C0015923
Disease	low density lipoprotein cholesterol measurement, physical activity	TRPS1 PRDM15 DNAH11	2.73e-03	66	124	3	EFO_0003940, EFO_0004611
Disease	portal hypertension (implicated_via_orthology)	TIMP2 NR1H4	2.86e-03	19	124	2	DOID:10762 (implicated_via_orthology)
Disease	Bladder Neoplasm	HDAC4 KMT2C KMT2D TIMP2	2.93e-03	140	124	4	C0005695
Disease	freckles	BNC2 EXOC2	3.17e-03	20	124	2	EFO_0003963
Disease	Contact Dermatitis	NRG1 HDAC4 IGFBP2	3.36e-03	71	124	3	C0011616
Disease	Contact hypersensitivity	NRG1 HDAC4 IGFBP2	3.36e-03	71	124	3	C0162351
Disease	muscular dystrophy (implicated_via_orthology)	TRIM63 POPDC3	3.49e-03	21	124	2	DOID:9884 (implicated_via_orthology)
Disease	C-peptide measurement	MUC19 MAP4K5	3.83e-03	22	124	2	EFO_0005187
Disease	breast carcinoma	ATG10 CCDC30 TBC1D5 TRPS1 TSPAN16 ZNF37A BRCA2 ANKRD30A SNTG1 NCOA1 DNAH11	3.85e-03	1019	124	11	EFO_0000305
Disease	non-small cell lung carcinoma	NRG1 BRCA2 NR1H4	3.92e-03	75	124	3	EFO_0003060
Disease	red blood cell density measurement	ZYG11A SHLD2 NRG1 TRPS1 RICTOR IKZF1 KIF20B MAP4K5 SORCS2 KLRC2	4.07e-03	880	124	10	EFO_0007978
Disease	Carcinoma of lung	RICTOR BRCA2	4.18e-03	23	124	2	C0684249
Disease	hippocampal sclerosis of aging	MRM1 SORCS2	4.18e-03	23	124	2	EFO_0005678

Protein segments in the cluster

Peptide	Gene	Start	Entry
GLVHLCCSKVQNYSM	PRAMEF33	176	A0A0G2JMD5
IMKIHNFTSKCLYCN	ADNP	481	Q9H2P0
GMQVNRLSSCCEYKH	ERICH3	356	Q5RHP9
KIKHRCTIEGCNMVF	BNC2	466	Q6ZN30
VCTEQCVMSGHFDKK	ATG16L1	456	Q676U5
KVHLMGYNCNATTKC	ADAM18	616	Q9Y3Q7
VNKYKCTALMLAVCH	ANKRD30A	201	Q9BXX3
CKQLYNEHMKQIECG	DNAH11	606	Q96DT5
HAAKCMSASYQEAKC	ADAD1	536	Q96M93
KDCSDGYMCKIHFQI	ATG10	36	Q9H0Y0
MANVLGLDTCKHYKE	ADCY10	561	Q96PN6
VVSYEIKDMCIKCFH	CFAP44	661	Q96MT7
HILNYVMCKGLEKSD	NBEAL1	1446	Q6ZS30
VEKEKYCGDKTCMHT	CHML	176	P26374
HDPIKATEIMCYECK	PATE2	21	Q6UY27
LCYGVMTSCSLKHKQ	PATE2	41	Q6UY27
CMYTGLLTEIQCKSK	NR1H4	206	Q96RI1
VGIMCVVAYCKTKKQ	NRG1	256	Q02297
TCLMISCYKGHKEIA	FEM1C	151	Q96JP0
CDHMSVAKLSCGNVK	OR52N4	181	Q8NGI2
SKMLVCDTCDKGYHT	KMT2C	401	Q8NEZ4
LVYDTLMLKHQCTCG	HDAC4	656	P56524
ECAKQTKQMVDCSHY	SPINK9	21	Q5DT21
GYLFCKTLCMDAVQH	MGAM	561	O43451
ILQLMHSCKEGYVKD	EXOC2	381	Q96KP1
CDKHGLYNLKQCKMS	IGFBP2	261	P18065
KPLHYTTIMCGNACV	OR4F5	121	Q8NH21
QMAKCTGECEKTAKY	MUC19	8311	Q7Z5P9
ALGCCVYEMATLKHA	NEK4	191	P51957
GSVHLCCTKVVNYSM	PRAMEF18	176	Q5VWM3
GKGKICMIVNISQCY	KIF20B	446	Q96Q89
NLCKYTVHDQCAMKA	DGKA	236	P23743
DKVVCVGMNYVDHCK	FAHD2A	106	Q96GK7
GKVAQTACMSACKHL	EXOC6B	661	Q9Y2D4
CPHCSKQYSSKTKMV	PRDM10	836	Q9NQV6
GEQMKVYKCEHCRVL	IKZF1	456	Q13422
KPLHYTTIMCGNACV	OR4F17	121	Q8NGA8
EEKSTACQMLVCYAK	IPO5	676	O00410
HGVKMLEKCSVFQCL	RICTOR	671	Q6R327
QLMCSKSCCVYFHKI	DZIP3	276	Q86Y13
YKAQSSCCHFMVKLL	HSH2D	71	Q96JZ2
QITMLKGHYKTVDCC	ERCC8	326	Q13216
MKKTTRSQHICCYEC	GPRC6A	531	Q5T6X5
EKYQEQHSVMCKICE	PEX19	216	P40855
SEMHKKCYKNGICRL	DEFB134	26	Q4QY38
SQVRCYVHIMKEGLC	EIF2B3	296	Q9NR50
AVCVLKEKCMDYFHV	IL6ST	46	P40189
QSKAIKFYMHDICIC	CABIN1	1071	Q9Y6J0
KSKICQTKIMAGCYE	BRCA2	1881	P51587
LTLKDIHNCQYVACM	DNAH17	2556	Q9UFH2
SILSKCCHAMVALIY	DENND2A	776	Q9ULE3
DKVVCVGMNYVDHCK	FAHD2B	106	Q6P2I3
TKMCSSLTAEYKHCQ	CCDC30	301	Q5VVM6
KMHYISCIFQKCINF	ANKMY2	221	Q8IV38
KCTGSLQYVHQDCMK	MARCHF7	571	Q9H992
SMHKDYAVVLCCLGA	CUL9	1066	Q8IWT3
TCHCGEEAMKKYSQI	IL20	131	Q9NYY1
GLIYDSVMLKHQCSC	HDAC7	521	Q8WUI4
KSYLCCEHHKAMIAG	METTL13	466	Q8N6R0
CAVQVKNTGKMYACK	GRK7	206	Q8WTQ7
KTVKDSYHIMCRPCA	C9orf85	76	Q96MD7
VTLEKEHCYAMQGKT	POPDC3	136	Q9HBV1
EHCYAMQGKTSIDKL	POPDC3	141	Q9HBV1
SCKVSQFIHLYLMGC	CALCRL	211	Q16602
IFMVKECKHCNIVAY	MAP4K5	66	Q9Y4K4
LQTSKYCPMCNIKIH	PCGF1	76	Q9BSM1
TKQVTCRYFMHGVCK	MKRN1	56	Q9UHC7
YCEHMAVVKLACSET	OR52L1	196	Q8NGH7
YCEHMAVVKLACSET	OR52L2P	196	Q8NGH6
KPLHYTTIMCGNACV	OR4F4	121	Q96R69
QICGTHRQTKKMFCD	TRIM43	91	Q96BQ3
QMCGTHRETKKIFCE	TRIM49	91	P0CI25
HMGCLKKYETVQDIL	TOP2B	1026	Q02880
SAQCGSSMIYHCKHK	KLRC2	216	P26717
SCYATVCLKEIMKHD	PUS7L	686	Q9H0K6
IQCKTYACVLESHLM	SNTG1	396	Q9NSN8
KLDTMCRYQVHQGVC	MRM1	106	Q6IN84
TMLSAHTKCKLCYPQ	NCOA1	336	Q15788
IMEVHKEKGYGCSIC	PRDM15	1011	P57071
MKFTKAQAVVYCTCS	NSUN7	426	Q8NE18
HLCCTKVVNYSMSIL	PRAMEF22	181	A3QJZ6
YVTCAIHNCSEKMLT	SORCS2	321	Q96PQ0
KYNCLVMVLSPCHVK	SHLD2	441	Q86V20
SMEFIECCIDGHKYK	ATP11C	421	Q8NB49
TCSMCKVFGIHKACE	TRIM63	141	Q969Q1
QKTCKYTEHGKTCDM	ZNF37A	171	P17032
LVMEKLKCCGVNNYT	TSPAN16	146	Q9UKR8
KCVHCGIVFLDEVMY	TRPS1	1216	Q9UHF7
MHTGEKPYTCEECVK	ZNF876P	1	Q49A33
MSIHTGESKYLCSVC	ZBTB11	726	O95625
MITHTGEKPYECKQC	ZNF555	331	Q8NEP9
TNGMCSVCYKEHLQR	ZFAND5	26	O76080
VCQKDLCCHLSYKMS	VNN1	356	O95497
HMEDGIYTCPVCIKK	RLF	576	Q13129
QTIHCEPCYSKIMAK	SCEL	671	O95171
QMCGTHRETKKIFCE	TRIM49C	91	P0CI26
TNGMCSVCYKEHLQR	ZFAND6	26	Q6FIF0
CKKYGKSFCMVSQLH	ZNF679	186	Q8IYX0
TYCDAHRAGCKLVMV	SCTR	206	P47872
KKSLNHRYQMGCECK	TIMP2	141	P16035
TTCSEHCLQKYLKMT	TIMM9	46	Q9Y5J7
QRIHTGEKSYICMKC	ZNF585B	401	Q52M93
GLVHLCCSKVQNYSM	PRAMEF10	176	O60809
KCDVEYSNKTHIICM	PKHD1L1	2131	Q86WI1
SCEICEKKFYTMAHV	ZBTB47	521	Q9UFB7
AQKVLKCMYCGHSFE	TSHZ3	271	Q63HK5
QRIHTGEKSYICMKC	ZNF585A	401	Q6P3V2
QLCSEMVTIKLKCGH	ZNFX1	1396	Q9P2E3
QIIHTGMKPYECKQC	ZNF404	206	Q494X3
ECGKAFAYMSCLVKH	ZNF350	406	Q9GZX5
MVHTGEKRYKCEECG	ZNF225	336	Q9UK10
TYCKPHMQTKSCQTD	ZMYM2	861	Q9UBW7
KLYVCTECVMGFTQK	ZNF41	311	P51814
GVCQSMCHDKYTKIF	ZMYND11	461	Q15326
LIIHTGEKPYKCMEC	ZNF543	246	Q08ER8
ICSVKMEVSKCARYG	SLC30A5	291	Q8TAD4
QMCGTHRETKKIFCE	TRIM49D1	91	C9J1S8
CKSMDECKVHKECYN	ZNF98	126	A6NK75
MTTHTGEKPYKCQHC	ZNF57	271	Q68EA5
THTGIKAFKCQYCMK	ZNF236	531	Q9UL36
IYKCAMCDTVFTHKP	ZNF687	826	Q8N1G0
QICGTHRQTKKMFCD	TRIM43B	91	A6NCK2
VQFHILGMKCKICES	RCHY1	231	Q96PM5
LGMKCKICESYNTAQ	RCHY1	236	Q96PM5
MNSHVKEKPYTCSIC	ZNF597	231	Q96LX8
VKHSNEKKMYRCTAC	ZNF423	741	Q2M1K9
CKYCAKVMDTHLVNI	TBC1D5	606	Q92609
YQGKCSHCMRIGVAV	USP31	326	Q70CQ4
QKIHTDEKTYKCMEC	ZNF529	301	Q6P280
CICIHLKSNTEKFYM	POLR1B	331	Q9H9Y6
CEICEKKFYTMAHVR	ZNF652	331	Q9Y2D9
HVCSKNPSKYCKMLV	ZYG11A	696	Q6WRX3
GTSTMCGHYVCHIKK	USP5	811	P45974
EDAQKVLKCMYCGHS	TSHZ1	301	Q6ZSZ6
VLKCMYCGHSFESLQ	TSHZ1	306	Q6ZSZ6
HCKMCSYCLQTSPKL	ZMYM4	771	Q5VZL5
VHMGEKRYKCDVCSK	ZNF284	196	Q2VY69
QKMHTVKTPYECQEC	ZNF473	506	Q8WTR7
SKMLVCETCDKGYHT	KMT2D	286	O14686
KTVEVETPHCAMCLY	KCNJ1	346	P48048
ECKRCVHKATNMEYA	RPS6KA1	431	Q15418