Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin filament binding

SPTBN1 SPTBN2 TRIOBP ACTR3B SPTBN5 MYH14 MYO1F MYH15 PLEC MYO18B

5.53e-0522718610GO:0051015
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1A CACNA1B CACNA1E

6.41e-0591863GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1A CACNA1B CACNA1E

6.41e-0591863GO:0099626
GeneOntologyMolecularFunctionsulfate adenylyltransferase (ATP) activity

PAPSS2 PAPSS1

8.63e-0521862GO:0004781
GeneOntologyMolecularFunctionsulfate adenylyltransferase activity

PAPSS2 PAPSS1

8.63e-0521862GO:0004779
GeneOntologyMolecularFunctionadenylylsulfate kinase activity

PAPSS2 PAPSS1

8.63e-0521862GO:0004020
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF1A DYNC2H1 MYH14 MYO1F MYH15 MYO18B DNAH6

1.20e-041181867GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DYNC2H1 CCDC88B HOOK2 DNAH6

1.25e-04281864GO:0051959
GeneOntologyMolecularFunctionactin binding

TRPM7 SPTBN1 SPTBN2 TRIOBP ACTR3B SPTBN5 MYH14 MYO1F PPP1R18 MYH15 MICAL3 PLEC MYO18B CROCC

1.66e-0447918614GO:0003779
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1B CACNA1E

2.68e-04141863GO:0008331
GeneOntologyMolecularFunctionpyrophosphatase activity

DHX16 ABCA2 NUDT16 KIF1A ABCA12 DYNC2H1 SMC1A NVL YTHDC2 RFC2 BCS1L CILP2 TSR1 RAB30 ACIN1 RASEF DNAH6 RAB3A RAB33B

3.26e-0483918619GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DHX16 ABCA2 NUDT16 KIF1A ABCA12 DYNC2H1 SMC1A NVL YTHDC2 RFC2 BCS1L CILP2 TSR1 RAB30 ACIN1 RASEF DNAH6 RAB3A RAB33B

3.31e-0484018619GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DHX16 ABCA2 NUDT16 KIF1A ABCA12 DYNC2H1 SMC1A NVL YTHDC2 RFC2 BCS1L CILP2 TSR1 RAB30 ACIN1 RASEF DNAH6 RAB3A RAB33B

3.31e-0484018619GO:0016818
GeneOntologyMolecularFunctionATP-dependent activity

DHX16 ABCA2 KIF1A ABCA12 DYNC2H1 SMC1A NVL YTHDC2 RFC2 BCS1L MYH14 MYO1F ACIN1 MYH15 DNAH6

6.55e-0461418615GO:0140657
GeneOntologyMolecularFunctioncalcium ion binding

CACNA1B CACNA1E DCHS2 EFCAB11 PCDHGA2 BCAN PCDH17 HMCN2 DHH CABP4 USP32 RASEF CDH3 PCDH8 PCDH9 CALN1 RCN3

6.59e-0474918617GO:0005509
GeneOntologyMolecularFunctioncalmodulin-dependent protein phosphatase activity

PPP3CC PPM1F

8.47e-0451862GO:0033192
GeneOntologyMolecularFunctionATP hydrolysis activity

DHX16 ABCA2 KIF1A ABCA12 DYNC2H1 SMC1A NVL YTHDC2 RFC2 BCS1L ACIN1 DNAH6

9.11e-0444118612GO:0016887
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DHX16 ABCA2 KIF1A ABCA12 DYNC2H1 SMC1A NVL YTHDC2 RFC2 BCS1L TSR1 RAB30 ACIN1 RASEF DNAH6 RAB3A RAB33B

9.60e-0477518617GO:0017111
GeneOntologyMolecularFunctionmyosin binding

TRPM7 TRIOBP SPTBN5 SNAP25 RAB3A

1.19e-03851865GO:0017022
GeneOntologyMolecularFunctionankyrin binding

SPTBN1 OBSCN PLEC

1.23e-03231863GO:0030506
GeneOntologyMolecularFunctioncalcium channel activity

SLC24A5 CACNA1A CACNA1B CACNA1E TRPM7 PKD1

1.33e-031291866GO:0005262
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF1A TRPM7 SPTBN1 SPTBN2 OBSCN TRIOBP ACTR3B CCDC88B SPTBN5 MYH14 MYO1F PPP1R18 ROCK1 MYH15 MICAL3 HOOK2 SNAP25 PLEC MYO18B CROCC RAB3A

1.43e-03109918621GO:0008092
GeneOntologyMolecularFunctioncalmodulin binding

CACNA1A WFS1 SPTBN1 OBSCN PPP3CC MYH14 MYO1F MYH15

1.45e-032301868GO:0005516
GeneOntologyMolecularFunctionpreribosome binding

NVL ZNF622

2.33e-0381862GO:1990275
GeneOntologyMolecularFunctioncalcium-dependent protein serine/threonine phosphatase activity

PPP3CC PPM1F

2.33e-0381862GO:0004723
GeneOntologyBiologicalProcessendomembrane system organization

CACNA1B DNAJC13 DYNC2H1 SPTBN1 OBSL1 ZBED3 RTN1 SPTBN5 COG1 FER1L4 RAB30 TJAP1 HOOK2 SNAP25 PLEC RAB3A DOP1B RAB33B RNF26

1.13e-0567218619GO:0010256
GeneOntologyBiologicalProcessactomyosin structure organization

TRPM7 OBSCN OBSL1 ARHGEF18 ARHGAP6 MYH14 PPM1F ROCK1 MYOM2 PLEC MYO18B

1.16e-0523918611GO:0031032
GeneOntologyBiologicalProcessactin cytoskeleton organization

TRPM7 SPTBN1 SPTBN2 OBSCN OBSL1 TRIOBP ARHGEF18 BCL2 ARHGEF11 ZBED3 SPTBN5 ARHGAP6 MYH14 PPM1F MYO1F ROCK1 MICAL3 MYOM2 HAX1 PLEC MYO18B

1.24e-0580318621GO:0030036
GeneOntologyBiologicalProcessactin filament-based process

TRPM7 SPTBN1 SPTBN2 OBSCN OBSL1 TRIOBP ARHGEF18 BCL2 ARHGEF11 ZBED3 SPTBN5 ARHGAP6 MYH14 PPM1F MYO1F ROCK1 MICAL3 MYOM2 HAX1 PLEC MYO18B ACAP2

2.64e-0591218622GO:0030029
GeneOntologyBiologicalProcesssynaptic vesicle cycle

CACNA1A CACNA1B CACNA1E SPTBN2 PCDH17 AP2M1 PPP3CC ROCK1 SNAP25 FBXL20 RAB3A

2.91e-0526418611GO:0099504
GeneOntologyBiologicalProcesscell morphogenesis

SEMA6C CACNA1A LZTS3 KIF1A CNTNAP1 OBSL1 TRIOBP SPART ARHGEF18 LAMC3 BCAN BCL2 PRAG1 GRHL2 ARHGAP4 BMPR2 HMCN2 MYH14 CABP4 ROCK1 SNAP25 PLEC RAB3A CDH3 RASAL1

7.45e-05119418625GO:0000902
GeneOntologyBiologicalProcess3'-phosphoadenosine 5'-phosphosulfate biosynthetic process

PAPSS2 PAPSS1

8.09e-0521862GO:0050428
GeneOntologyBiologicalProcesspurine ribonucleoside bisphosphate biosynthetic process

PAPSS2 PAPSS1

8.09e-0521862GO:0034036
GeneOntologyBiologicalProcesssynaptic vesicle exocytosis

CACNA1A CACNA1B CACNA1E SPTBN2 SNAP25 FBXL20 RAB3A

1.41e-041251867GO:0016079
GeneOntologyCellularComponentmyosin filament

OBSCN MYH14 MYH15 MYOM2 MYO18B

2.63e-06251895GO:0032982
GeneOntologyCellularComponentspectrin

SPTBN1 SPTBN2 SPTBN5

5.87e-0591893GO:0008091
GeneOntologyCellularComponentA band

PPP1R12A SPTBN1 OBSCN OBSL1 MYOM2

1.06e-04521895GO:0031672
GeneOntologyCellularComponentpresynapse

CACNA1A CACNA1B CACNA1E KIF1A TRPM7 WFS1 SPTBN2 CNTNAP1 PCDH17 MADD SLC6A3 AP2M1 PPP3CC CABP4 CNTNAP4 SNAP25 FBXL20 RAB3A PCDH8 RAB33B

1.61e-0488618920GO:0098793
GeneOntologyCellularComponentM band

SPTBN1 OBSCN OBSL1 MYOM2

1.68e-04311894GO:0031430
DomainP-loop_NTPase

DHX16 ABCA2 KIF1A ABCA12 DYNC2H1 SMC1A NVL YTHDC2 GAL3ST2 RFC2 PAPSS2 PAPSS1 BCS1L TRANK1 SBNO1 MYH14 RAB30 MYO1F RASEF MYH15 MYO18B DNAH6 RAB3A RAB33B

3.59e-0684818524IPR027417
DomainPH

KIF1A SPTBN1 SPTBN2 TBC1D2 OBSCN TRIOBP ARHGEF18 SPTBN5 ROCK1 ACAP2 RASAL1

1.84e-0522918511PF00169
DomainPH

KIF1A SPTBN1 SPTBN2 TBC1D2 OBSCN TRIOBP ARHGEF18 ARHGEF11 SPTBN5 ROCK1 ACAP2 RASAL1

2.22e-0527818512SM00233
DomainPH_DOMAIN

KIF1A SPTBN1 SPTBN2 TBC1D2 OBSCN TRIOBP ARHGEF18 ARHGEF11 SPTBN5 ROCK1 ACAP2 RASAL1

2.30e-0527918512PS50003
DomainPH_domain

KIF1A SPTBN1 SPTBN2 TBC1D2 OBSCN TRIOBP ARHGEF18 ARHGEF11 SPTBN5 ROCK1 ACAP2 RASAL1

2.38e-0528018512IPR001849
DomainCa_chan_IQ

CACNA1A CACNA1B CACNA1E

3.25e-0571853SM01062
DomainCa_chan_IQ

CACNA1A CACNA1B CACNA1E

3.25e-0571853PF08763
DomainVDCC_a1su_IQ

CACNA1A CACNA1B CACNA1E

3.25e-0571853IPR014873
DomainGPHH

CACNA1A CACNA1B CACNA1E

3.25e-0571853PF16905
DomainGPHH_dom

CACNA1A CACNA1B CACNA1E

3.25e-0571853IPR031649
DomainACTININ_2

SPTBN1 SPTBN2 SPTBN5 PLEC

7.12e-05231854PS00020
DomainACTININ_1

SPTBN1 SPTBN2 SPTBN5 PLEC

7.12e-05231854PS00019
DomainActinin_actin-bd_CS

SPTBN1 SPTBN2 SPTBN5 PLEC

7.12e-05231854IPR001589
DomainPH_dom-spectrin-type

SPTBN1 SPTBN2 SPTBN5

7.69e-0591853IPR001605
DomainPH_dom-like

KIF1A SPTBN1 SPTBN2 TBC1D2 OBSCN TRIOBP ARHGEF18 ARHGEF11 SPTBN5 SPRED1 ROCK1 LRBA ACAP2 RASAL1

9.21e-0542618514IPR011993
DomainSulfurylase_cat_dom

PAPSS2 PAPSS1

9.76e-0521852IPR024951
DomainATP-sulfurylase

PAPSS2 PAPSS1

9.76e-0521852PF01747
DomainPUA_2

PAPSS2 PAPSS1

9.76e-0521852PF14306
DomainAPS_kinase

PAPSS2 PAPSS1

9.76e-0521852IPR002891
DomainSulphate_adenylyltransferase

PAPSS2 PAPSS1

9.76e-0521852IPR002650
DomainATP-Sase_PUA-like_dom

PAPSS2 PAPSS1

9.76e-0521852IPR025980
DomainTMEM191C

TMEM191C TMEM191B

9.76e-0521852PF15194
DomainTMEM191B/C

TMEM191C TMEM191B

9.76e-0521852IPR028186
DomainVDCCAlpha1

CACNA1A CACNA1B CACNA1E

1.09e-04101853IPR002077
Domain-

KIF1A SPTBN1 SPTBN2 TBC1D2 OBSCN TRIOBP ARHGEF18 ARHGEF11 SPTBN5 SPRED1 ROCK1 ACAP2 RASAL1

1.47e-04391185132.30.29.30
Domain-

DHX16 ABCA2 ABCA12 DYNC2H1 SMC1A NVL YTHDC2 RFC2 PAPSS2 PAPSS1 BCS1L TRANK1 SBNO1 RAB30 MYO1F RASEF DNAH6 RAB3A RAB33B

1.60e-04746185193.40.50.300
DomainSpectrin_repeat

SPTBN1 SPTBN2 SPTBN5 PLEC

1.82e-04291854IPR002017
DomainSPEC

SPTBN1 SPTBN2 SPTBN5 PLEC

2.70e-04321854SM00150
DomainSpectrin/alpha-actinin

SPTBN1 SPTBN2 SPTBN5 PLEC

2.70e-04321854IPR018159
DomainCH

SPTBN1 SPTBN2 SPTBN5 MICAL3 PLEC

4.61e-04651855SM00033
DomainMyosin_head_motor_dom

MYH14 MYO1F MYH15 MYO18B

5.29e-04381854IPR001609
DomainMYOSIN_MOTOR

MYH14 MYO1F MYH15 MYO18B

5.29e-04381854PS51456
DomainMyosin_head

MYH14 MYO1F MYH15 MYO18B

5.29e-04381854PF00063
DomainMYSc

MYH14 MYO1F MYH15 MYO18B

5.29e-04381854SM00242
DomainSpectrin_bsu

SPTBN1 SPTBN2

5.78e-0441852IPR016343
DomainAAA

ABCA2 ABCA12 DYNC2H1 NVL RFC2 BCS1L DNAH6

5.87e-041441857SM00382
DomainAAA+_ATPase

ABCA2 ABCA12 DYNC2H1 NVL RFC2 BCS1L DNAH6

5.87e-041441857IPR003593
DomainCH

SPTBN1 SPTBN2 SPTBN5 MICAL3 PLEC

6.49e-04701855PF00307
Domain-

SPTBN1 SPTBN2 SPTBN5 MICAL3 PLEC

6.93e-047118551.10.418.10
DomainCadherin_CS

DCHS2 PCDHGA2 PCDH17 CDH3 PCDH8 PCDH9

7.58e-041091856IPR020894
DomainCH

SPTBN1 SPTBN2 SPTBN5 MICAL3 PLEC

7.87e-04731855PS50021
DomainMyosin-like_IQ_dom

MYH14 MYH15 MYO18B

8.24e-04191853IPR027401
Domain-

MYH14 MYH15 MYO18B

8.24e-041918534.10.270.10
DomainCH-domain

SPTBN1 SPTBN2 SPTBN5 MICAL3 PLEC

8.90e-04751855IPR001715
DomainCADHERIN_1

DCHS2 PCDHGA2 PCDH17 CDH3 PCDH8 PCDH9

9.16e-041131856PS00232
DomainCadherin

DCHS2 PCDHGA2 PCDH17 CDH3 PCDH8 PCDH9

9.16e-041131856PF00028
DomainCADHERIN_2

DCHS2 PCDHGA2 PCDH17 CDH3 PCDH8 PCDH9

9.59e-041141856PS50268
Domain-

DCHS2 PCDHGA2 PCDH17 CDH3 PCDH8 PCDH9

9.59e-0411418562.60.40.60
DomainCA

DCHS2 PCDHGA2 PCDH17 CDH3 PCDH8 PCDH9

1.00e-031151856SM00112
DomainCadherin-like

DCHS2 PCDHGA2 PCDH17 CDH3 PCDH8 PCDH9

1.05e-031161856IPR015919
DomainCadherin

DCHS2 PCDHGA2 PCDH17 CDH3 PCDH8 PCDH9

1.15e-031181856IPR002126
DomainSPOC_C

RBM15 DIDO1

1.43e-0361852IPR012921
DomainHOOK

CCDC88B HOOK2

1.43e-0361852PF05622
DomainHook-related_fam

CCDC88B HOOK2

1.43e-0361852IPR008636
DomainSPOC

RBM15 DIDO1

1.43e-0361852PF07744
DomainSpectrin

SPTBN1 SPTBN2 SPTBN5

1.46e-03231853PF00435
DomaintRNA-bd_arm

FYCO1 CNTLN CROCC

1.66e-03241853IPR010978
DomainEF_HAND_2

CACNA1B CACNA1E EFCAB11 CABP4 USP32 RASEF CALN1 RCN3

2.18e-032311858PS50222
DomainEF_hand_dom

CACNA1B CACNA1E EFCAB11 CABP4 USP32 RASEF CALN1 RCN3

2.24e-032321858IPR002048
DomainIQ

OBSCN MYH14 MYO1F MYH15 MYO18B

2.32e-03931855PS50096
PathwayBIOCARTA_RHO_PATHWAY

ARHGEF11 ARHGAP4 ARHGAP6 ROCK1

2.94e-05211234M1001
PathwayPID_RHOA_REG_PATHWAY

OBSCN ARHGEF18 ARHGEF11 ARHGAP4 ARHGAP6

4.80e-05461235M68
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTBN1 SPTBN2 SPTBN5

7.44e-05101233MM15112
PathwayWP_SYNAPTIC_VESICLE_PATHWAY

CACNA1A CACNA1B AP2M1 SNAP25 RAB3A

7.94e-05511235M39457
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B CACNA1E

1.02e-04111233MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B CACNA1E

1.02e-04111233M26913
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1A CACNA1B CACNA1E

1.02e-04111233M47958
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DCHS2 RBM11 ABCA2 GAMT TTC28 KIF1A TRPM7 SMC1A TAF1C SPTBN1 SPTBN2 CNTNAP1 OBSL1 TRIOBP BTBD2 ACTR3B MADD SNRNP48 AP2M1 SBNO1 COG1 MYH14 USP32 PKD1 SPRED1 SNAP25 PLEC LRBA HERC2 TNKS2 HSD17B4 WDR13 DOP1B

1.50e-1312851913335914814
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX16 RBM15 HK1 KIF1A SPTBN1 SPTBN2 NOL6 NVL DIDO1 YTHDC2 GTF3C3 TSR1 MYH14 RBM6 ACIN1 PLEC HERC2 NUP160 MED12 RBM34

6.86e-106531912022586326
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

CACNA1A CACNA1B CACNA1E KIF1A SPTBN1 NVL CHCHD6 YTHDC2 ACTR3B MADD RPS6KC1 PRR12 PI4KA USP39 HERC2 HSD17B4 PZP

1.38e-094751911731040226
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

DCHS2 RBM15 PPP1R12A SPTBN1 SPTBN2 OBSCN YTHDC2 ARHGEF11 STAT5A TRANK1 USP32 MICAL3 MYOM2 USP39 LRBA MED12 RBM34

2.72e-094971911736774506
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA6C ABCA2 MAN2B1 OBSCN LAMC3 FYCO1 ARHGEF11 ZBED3 PRAG1 MADD ESRP2 PRR12 TNRC18 AATK PI4KA PKD1 MICAL3 PLEC LRBA HERC2 ANKRD33B MED12 RASAL1 AHNAK2

1.11e-0811051912435748872
Pubmed

An action potential initiation mechanism in distal axons for the control of dopamine release.

CACNA1A CACNA1B CACNA1E SLC6A3

1.31e-086191435324301
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A CACNA1E DNAJC13 LZTS3 PPP1R12A SPTBN1 SPTBN2 CNTNAP1 WDR81 TRIOBP ARHGEF18 DIDO1 FYCO1 ARHGEF11 RTN1 PI4KA TJAP1 ROCK1 HERC2 RAB3A PCDH8 RASAL1

1.97e-089631912228671696
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DHX16 RBM15 DNAJC13 DIS3L2 HK1 SMC1A TAF1C SPTBN1 NOL6 CHCHD6 RFC2 PAPSS2 GTF3C3 AP2M1 MYH14 PPM1F PI4KA ACIN1 MMS19 PLEC HERC2 WDR13 NUP160 MED12 RBM34 AHNAK2

3.08e-0813531912629467282
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DNAJC13 KIF1A TRPM7 WFS1 WDR81 FYCO1 HS1BP3 RTN1 CLCC1 MADD RPS6KC1 PI4KA USP32 LRBA DOP1B

1.47e-075041911534432599
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

DHX16 RBM15 DNAJC13 HK1 SMC1A SPTBN1 SPTBN2 TRIOBP DIDO1 HS1BP3 GTF3C3 SNRNP48 AP2M1 TSR1 RBM6 ACIN1 HAX1 USP39 PLEC HSD17B4 PZP MED12

1.49e-0710821912238697112
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1B CACNA1E

1.63e-073191338996073
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1B CACNA1E

1.63e-073191324523520
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RBM15 CCDC8 DNAJC13 SMC1A NOL6 NVL ZNF622 DIDO1 YTHDC2 RFC2 GTF3C3 AP2M1 TSR1 RBM6 ACIN1 HERC2 MED12 RBM34

2.40e-077591911835915203
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

DHX16 RBM11 ARID4A C9orf78 SMC1A NVL DIDO1 RFC2 GTF3C3 SBNO1 TSR1 SUV39H1 USP39 HERC2 ZHX1 RBM34

2.94e-076081911636089195
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CACNA1A DNAJC13 HK1 LZTS3 WFS1 PPP1R12A SPTBN1 SPTBN2 CNTNAP1 YTHDC2 BCAN ACTR3B ARHGEF11 RTN1 MADD AP2M1 MYH14 PI4KA PPP1R18 MICAL3 HAX1 PLEC CROCC DNAH6 RASAL1

3.48e-0714311912537142655
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

CACNA1E LZTS3 SPTBN1 SPTBN2 CNTNAP1 ARHGEF18 CHCHD6 PRAG1 PI4KA RAB3A RASAL1

5.03e-072811911128706196
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1A CACNA1B CACNA1E SPTBN1 CNTNAP1 BCAN RTN1 MADD BMPR2 MICAL3 PLEC RAB3A

5.65e-073471911217114649
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

RBM15 RBM11 TTC28 ARID4A C9orf78 PPP1R12A HAUS5 SPART TSR1 MYH14 PI4KA ROCK1 MICAL3 LRBA ACAP2 MED12

6.40e-076451911625281560
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1A CACNA1B CACNA1E

6.50e-074191337141091
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1A CACNA1B CACNA1E

6.50e-074191332616470
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

DHX16 ABCA2 TTC28 SPTBN2 ARHGEF11 MADD AP2M1 CNTNAP4

6.55e-07130191812421765
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DHX16 COL6A2 MAN2B1 TTC28 NOL6 OBSL1 DIDO1 YTHDC2 PAPSS2 MADD PRR12 TSR1 MICAL3 HOOK2 HSD17B4 PZP

7.09e-076501911638777146
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DHX16 RBM15 HK1 KIF1A DYNC2H1 SMC1A SPTBN1 NOL6 LAMC3 YTHDC2 RFC2 GTF3C3 AP2M1 SBNO1 TSR1 MYH14 PI4KA ACIN1 HAX1 USP39 MYO18B HSD17B4 NUP160 RBM34

1.16e-0614251912430948266
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DHX16 RBM15 DNAJC13 ARID4A C9orf78 SMC1A SPTBN1 TBC1D2 DIDO1 YTHDC2 RBM6 PPP1R18 ACIN1 TJAP1 MICAL3 PLEC ZHX1

1.50e-067741911715302935
Pubmed

Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.

CACNA1A CACNA1B CACNA1E

1.62e-06519138825650
Pubmed

KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.

KIF1A MADD RAB3A

1.62e-065191318849981
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1A CACNA1B CACNA1E

1.62e-065191311296258
Pubmed

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.

CNTLN CEP250 CROCC

1.62e-065191324554434
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1A CACNA1B CACNA1E

1.62e-065191315451373
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

HK1 MAN2B1 C9orf78 PPP1R12A SMC1A SPTBN1 TBC1D2 ZNF622 RFC2 PAPSS2 PAPSS1 PRMT6 SBNO1 TSR1 MYH14 ALDH16A1 ROCK1 MMS19 PLEC LRBA CROCC NUP160 RASAL1 AHNAK2

1.67e-0614551912422863883
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

SPTBN2 DIDO1 ARHGEF11 MADD AREL1 TRANK1 HERC2

1.83e-0610419179205841
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

RBM15 RBM11 CCDC8 PPP1R12A SMC1A SPTBN1 NOL6 NVL DIDO1 GTF3C3 AP2M1 MYH14 DEDD2 NUP160 MED12

2.13e-066241911533729478
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

HAUS5 NVL ARHGEF18 DIDO1 MYH14 PI4KA ACIN1 MMS19 HAX1 USP39 MED12 RBM34

3.19e-064101911226949251
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

CACNA1A CACNA1B CACNA1E

3.22e-066191312827191
Pubmed

Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.

CACNA1A CACNA1B CACNA1E

3.22e-06619139238069
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

CACNA1B RBM15 CCDC8 DNAJC13 SPTBN2 OBSL1 SPTBN5 DCAF8L1 FER1L4 RBM6 PLEC MYO18B RBM34

4.12e-064961911331343991
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RBM15 DNAJC13 PPP1R12A SMC1A TAF1C NOL6 NVL RFC2 GTF3C3 PRR12 TSR1 MYH14 ACIN1 HAX1 USP39 HSD17B4 RBM34

4.96e-068471911735850772
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CACNA1A CACNA1B LZTS3 WFS1 SPTBN1 CNTNAP1 TRIOBP ACTR3B RTN1 MADD RPS6KC1 TNRC18 AP2M1 PI4KA HAX1 SNAP25 PLEC RAB3A PCDH8 RASAL1

5.24e-0611391912036417873
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

DHX16 RBM15 SPTBN1 TRIOBP DIDO1 PPP1R18 ACIN1 MICAL3 PLEC ACAP2 AHNAK2

5.51e-063601911133111431
Pubmed

Rebuilding essential active zone functions within a synapse.

CACNA1A CACNA1B CACNA1E

5.61e-067191335176221
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CCDC8 NOL6 NVL YTHDC2 FYCO1 GTF3C3 RPS6KC1 MYH14 RBM6 MMS19 HERC2 NUP160

6.53e-064401911234244565
Pubmed

The protein interaction landscape of the human CMGC kinase group.

RBM15 CCDC8 LZTS3 SMC1A MRPL43 OBSL1 WDR81 DIDO1 ACIN1 ROCK1 HAX1 USP39 HERC2 MED12 RBM34

7.79e-066951911523602568
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CCDC8 DNAJC13 HK1 TRPM7 DYNC2H1 WFS1 SPTBN1 SPTBN2 MRPL43 OBSL1 NVL TRIOBP SPART ZNF622 CHCHD6 BCS1L GTF3C3 CLCC1 TSR1 PI4KA HAX1 HERC2 RBM34

8.00e-0614871912333957083
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DNAJC13 KIF1A PPP1R12A OBSCN TRIOBP ARHGEF18 CHCHD6 GRHL2 CLCC1 RANBP17 PARP10 ARHGAP6 BMPR2 TNRC18 MYH14 RBM6 TJAP1 RASEF MICAL3 HOOK2 LRBA CROCC WDR13

8.18e-0614891912328611215
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DYNC2H1 SPTBN5 MYH14 PKD1 PLEC CROCC DNAH6 NUP160

9.85e-06187191826460568
Pubmed

NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.

SPTBN1 SPTBN2 PPP1R18 PLEC

1.02e-0525191430309841
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1A CACNA1B CACNA1E

1.34e-059191316382099
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

RBM15 C9orf78 PPP1R12A SMC1A MRPL43 ARHGEF18 ARHGEF11 CLCC1 ARHGAP4 ARHGAP6 AP2M1 RBM6 HAX1 USP39 PLEC TNKS2 HSD17B4

1.37e-059161911732203420
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

HK1 C9orf78 PPP1R12A SMC1A SPART RFC2 BCS1L CLCC1 AP2M1 ALDH16A1 MMS19 HAX1 NUP160

1.50e-055601911335241646
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MRI1 PPP1R12A SPTBN1 ACTR3B RFC2 MYH14 RASEF MMS19 HAX1 PLEC LRBA HSD17B4 PZP CDH3

1.53e-056471911426618866
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

DHX16 RBM15 CCDC8 SMC1A SPTBN2 HAUS5 NOL6 OBSL1 YTHDC2 RFC2 MYH14 PI4KA ACIN1 USP39 PLEC HERC2 HSD17B4 NUP160

1.57e-0510241911824711643
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CACNA1E HK1 PCDHGA2 PPP1R12A SPTBN1 SPTBN2 NOL6 RPS6KC1 TNRC18 SNRNP48 AP2M1 SBNO1 COG1 MYH14 ACIN1 MYH15 CFAP74 MYOM2 PLEC HSD17B4 DNAH6 RAB3A

1.58e-0514421912235575683
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

CACNA1A CACNA1E SPTBN1 CNTNAP1 BMPR2 AP2M1 AATK PPP3CC PI4KA SNAP25 PCDH8

1.66e-054051911138187761
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

SMC1A SPTBN1 DIDO1 RFC2 TSR1 ACIN1 MMS19 PLEC NUP160 AHNAK2

1.68e-053321911032786267
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

DHX16 RBM15 NOL6 NVL YTHDC2 RFC2 TSR1 ACIN1 NUP160 RBM34

1.68e-053321911025693804
Pubmed

Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity.

CNTNAP1 PARP10 PLEC

1.90e-0510191319625254
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

RBM15 PPP1R12A SPTBN1 NVL ACTR3B RFC2 ARHGEF11 AP2M1 PI4KA PPP1R18 ACIN1 USP39 PLEC NUP160

1.91e-056601911432780723
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

RBM15 SMC1A SPTBN1 RFC2 GTF3C3 PRR12 RBM6 PLEC MED12

2.14e-05272191931010829
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RBM15 CCDC8 DNAJC13 SPTBN1 SPTBN2 TRIOBP CLCC1 MADD PPP3CC TSR1 PPM1F PI4KA PPP1R18 ROCK1 MICAL3 HAX1 HERC2 HSD17B4

2.15e-0510491911827880917
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SMC1A SPTBN1 OBSCN LAMA4 SPART MYH14 SPRED1 MYOM2 HOOK2 PLEC MYO18B TNKS2

2.19e-054971911223414517
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

DHX16 C9orf78 PPP1R12A SMC1A HAUS5 MRPL43 TRIOBP CHCHD6 PCMTD1 PAPSS2 PAPSS1 GTF3C3 AP2M1 TSR1 PPP1R18 MICAL3 USP39 HERC2 NUP160

2.25e-0511551911920360068
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

DHX16 DPP4 RBM15 WFS1 TAF1C SPTBN1 SPTBN2 NOL6 MRPL43 OBSL1 DIDO1 RFC2 GTF3C3 AP2M1 TSR1 MYH14 ACIN1 HAX1 PLEC HERC2 RBM34

2.35e-0513711912136244648
Pubmed

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

SPTBN1 NOL6 RFC2 ACIN1 USP39 NUP160

2.46e-05104191626167872
Pubmed

Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.

COL6A2 CNTNAP4 MYOM2 MYO18B

2.47e-0531191422282597
Pubmed

delta-Protocadherins: a gene family expressed differentially in the mouse brain.

PCDH17 PCDH8 PCDH9

2.60e-0511191315905963
Pubmed

Functional proteomics mapping of a human signaling pathway.

MRI1 MAN2B1 SPTBN1 LAMA4 SPART BTBD2 CEP250 PKD1 SPRED1 ROCK1 PLEC HERC2 TNKS2

2.62e-055911911315231748
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

SPTBN1 MYO1F PPP1R18 PLEC ACAP2 NUP160 AHNAK2

2.64e-05156191730409884
Pubmed

A member of a family of sulfate-activating enzymes causes murine brachymorphism.

PAPSS2 PAPSS1

3.00e-05219129671738
Pubmed

Blocking the R-type (Cav2.3) Ca2+ channel enhanced morphine analgesia and reduced morphine tolerance.

CACNA1B CACNA1E

3.00e-052191215610184
Pubmed

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.

CACNA1A CACNA1B

3.00e-052191223426690
Pubmed

Nuclear localization of PAPS synthetase 1: a sulfate activation pathway in the nucleus of eukaryotic cells.

PAPSS2 PAPSS1

3.00e-052191210657990
Pubmed

Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization.

PAPSS2 PAPSS1

3.00e-052191210679223
Pubmed

Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.

CACNA1A CACNA1B

3.00e-052191223376566
Pubmed

Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25.

CACNA1A SNAP25

3.00e-05219128692999
Pubmed

Characterization and expression of human bifunctional 3'-phosphoadenosine 5'-phosphosulphate synthase isoforms.

PAPSS2 PAPSS1

3.00e-052191211931637
Pubmed

CaV 2.1 α1  subunit motifs that control presynaptic CaV 2.1 subtype abundance are distinct from CaV 2.1 preference.

CACNA1A CACNA1B

3.00e-052191238155373
Pubmed

Caspase-3/7-mediated Cleavage of β2-spectrin is Required for Acetaminophen-induced Liver Damage.

SPTBN1 SPTBN2

3.00e-052191226884715
Pubmed

Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm.

PAPSS2 PAPSS1

3.00e-052191222242175
Pubmed

An X chromosome-linked gene encoding a protein with characteristics of a rhoGAP predominantly expressed in hematopoietic cells.

ARHGAP4 ARHGAP6

3.00e-05219128570618
Pubmed

C2CD4A/B variants in the predisposition of lung cancer in the Chinese Han population.

C2CD4B C2CD4A

3.00e-052191235212842
Pubmed

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.

C2CD4B C2CD4A

3.00e-052191233492421
Pubmed

Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.

CACNA1A CACNA1E

3.00e-052191216381801
Pubmed

A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.

C2CD4B C2CD4A

3.00e-052191229625024
Pubmed

Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells.

CEP250 CROCC

3.00e-052191216339073
Pubmed

C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis.

CEP250 CROCC

3.00e-052191223070519
Pubmed

Sorting specificity of spermatogenic cell specific region of mouse hexokinase-s (mHk1-s).

HK1 BCL2

3.00e-052191212420306
Pubmed

Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse.

PAPSS2 PAPSS1

3.00e-05219129771708
Pubmed

Effects of ablation of N- and R-type Ca(2+) channels on pain transmission.

CACNA1B CACNA1E

3.00e-052191212074836
Pubmed

Expression analysis of P/Q-type Ca2+ channel alpha 1A subunit mRNA in olfactory mitral cell in N-type Ca2+ channel alpha 1B subunit gene-deficient mice.

CACNA1A CACNA1B

3.00e-052191215050706
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

RBM15 PPP1R12A SPTBN1 TRIOBP PRAG1 PRR12 PPP1R18 ACIN1 PLEC RBM34

3.42e-053611911030344098
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

RBM15 DNAJC13 DIDO1 YTHDC2 CCDC88B LRRC52 HMCN2 USP39 MYO18B DNAH6

3.42e-053611911026167880
Pubmed

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

C2CD4B C2CD4A MADD

3.46e-0512191321873549
Pubmed

alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.

SPTBN1 SPTBN2 SPTBN5

4.48e-0513191318796539
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

HK1 SPTBN1 SPTBN2 NOL6 MRPL43 TRIOBP ZNF622 YTHDC2 RFC2 CLCC1 AP2M1 COG1 PPP1R18 MICAL3 MMS19 HOOK2 HAX1 SNAP25 USP39 RBM34 AHNAK2

4.78e-0514401912130833792
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

DHX16 RBM15 SMC1A NVL DIDO1 RFC2 PAPSS1 GTF3C3 PRMT6 AP2M1 SBNO1 TSR1 ACIN1 MMS19 USP39 PLEC MED12

4.90e-0510141911732416067
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

PPP1R12A SPTBN1 TBC1D2 TRIOBP PPP1R18 AHNAK2

5.02e-05118191630979931
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1A CACNA1B CACNA1E TRPM7

5.62e-0538191430786075
Pubmed

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

OBSCN ARHGEF18 ARHGEF11 ARHGAP4

5.62e-0538191411756498
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

DHX16 HK1 ARID4A PPP1R12A SPTBN1 SPTBN2 DIDO1 LAMC3 MOSPD3 RFC2 MADD ALDH16A1 PKD1 TJAP1 HSD17B4 ACAP2

5.70e-059251911628986522
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

KIF1A SPTBN2 TBC1D2 OBSCN ZNF622 GAL3ST2 PCDH17 RPS6KC1 ESRP2 PI4KA ALDH16A1 PKD1 USP39 DOP1B

6.20e-057361911429676528
InteractionSIRT7 interactions

DHX16 RBM15 HK1 KIF1A SPTBN1 SPTBN2 NOL6 NVL DIDO1 YTHDC2 GTF3C3 TSR1 MYH14 RBM6 ACIN1 USP39 PLEC HERC2 NUP160 MED12 RBM34

6.03e-0674418721int:SIRT7
InteractionFBXO22 interactions

DCHS2 RBM15 PPP1R12A SPTBN1 SPTBN2 OBSCN YTHDC2 ARHGEF11 STAT5A TRANK1 USP32 MICAL3 MYOM2 USP39 LRBA MED12 RBM34

1.22e-0554018717int:FBXO22
Cytoband19q13.33

ODAD1 PRR12 MYH14 ALDH16A1 RCN3

8.53e-05106191519q13.33
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

CCDC8 PPP1R12A WDR81 CHCHD6 BCL2 AATK PPP1R18 SPRED1 PPP1R36

8.77e-061811359694
GeneFamilyEF-hand domain containing|Spectrins

SPTBN1 SPTBN2 SPTBN5

1.39e-05713531113
GeneFamilyNon-clustered protocadherins

PCDH17 PCDH8 PCDH9

8.53e-0512135321
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KIF1A SPTBN1 SPTBN2 TRIOBP ARHGEF18 ROCK1 ACAP2 RASAL1

1.59e-042061358682
GeneFamilyEF-hand domain containing

CACNA1B CACNA1E EFCAB11 CABP4 USP32 RASEF CALN1 RCN3

2.42e-042191358863
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1B CACNA1E

9.33e-04261353253
GeneFamilyRAB, member RAS oncogene GTPases

RAB30 RASEF RAB3A RAB33B

1.41e-03651354388
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC28 TTC36 GTF3C3 TRANK1 FKBPL

1.72e-031151355769
GeneFamilyWD repeat domain containing|BEACH domain containing

WDR81 LRBA

1.93e-03913521230
GeneFamilyLaminin subunits

LAMA4 LAMC3

3.48e-03121352626
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA12

4.75e-03141352805
GeneFamilyMyosin heavy chains

MYH14 MYH15

5.45e-031513521098
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_GHRL_POS_NE_PRECURSOR_CELL

CACNA1A RBM11 ABCA2 EFCAB11 LZTS3 KIF1A SPTBN2 ARHGEF11 PAPSS2 RTN1 PCDH17 MADD PKD1 MICAL3 SNAP25 RCN3 DOP1B

1.76e-0842919017M45694
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000

NRIP2 SEMA6C DNAJC13 TRPM7 SMC1A SPTBN1 DIDO1 TNRC18 SPRED1 PLEC PCDH9

2.40e-0525919111gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000

SLC24A5 SEMA6C EFCAB11 MAN2B1 GAMT INHBB OBSL1 LAMA4 PAPSS2 OLFML3 TNRC18 TRANK1 PPP3CC DHH RAB30 USP32 PACC1 MICAL3 PLEC PPP1R36 CDH3

4.66e-0588019121gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000

NRIP2 SEMA6C DPP4 DNAJC13 TRPM7 SMC1A SPTBN1 TNRC18 SPRED1 PLEC PCDH9

5.05e-0528119111gudmap_developingGonad_e18.5_epididymis_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#2_top-relative-expression-ranked_100

DPP4 ANKRD33B

8.05e-0521912gudmap_developingKidney_e15.5_Proximal Tubules_100_k2
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_1000

NRIP2 SEMA6C DPP4 DNAJC13 SMC1A SPTBN1 TNRC18 SPRED1 PLEC PCDH9

9.01e-0524919110gudmap_developingGonad_P2_epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

NRIP2 SEMA6C DPP4 COL6A2 DNAJC13 TRPM7 SMC1A SPTBN1 OBSL1 DIDO1 OLFML3 TNRC18 ACIN1 SPRED1 SNAP25 PLEC PCDH9 RCN3 AHNAK2

9.84e-0579019119gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3

SEMA6C CACNA1B PCDHGA2 MOSPD3 PAPSS2 GRHL2 PCDH17 RPS6KC1 ESRP2 RAB3A CDH3

1.25e-0431119111Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#2

SEMA6C CACNA1B PCDHGA2 MOSPD3 PAPSS2 GRHL2 PCDH17 RPS6KC1 ESRP2 RAB3A CDH3

1.32e-0431319111Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_200

CACNA1B LAMA4 RTN1 PCDH17 STAT5A SNAP25 TNKS2 CALN1

1.33e-041661918gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL DYNC2H1 ODAD1 CFAP74 ANKRD45 CROCC PZP DNAH6 AHNAK2

1.60e-071931919ea345d34440b25f65358a53dc72831998d1c3620
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CERKL CLCC1 PCDH17 TRANK1 USP32 MYO1F MYOM2 RCN3

3.01e-071511918b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A CYP8B1 SPTBN2 CCDC88B RTN1 MYO1F SNAP25 CALN1

1.14e-0618019186ac62bf1251978c8c12e715f7b73144fca619794
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A CERKL C2CD4B KIF1A SPTBN2 RTN1 CLEC4G SNAP25

1.19e-061811918cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TTC28 KIF1A WFS1 C2CD4A PAPSS2 MADD SNAP25

1.78e-0619119183387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TTC28 KIF1A WFS1 C2CD4A PAPSS2 MADD SNAP25

1.78e-061911918a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DPP4 OBSCN SPTBN5 PPP1R18 MYH15 ANKRD33B RASAL1

1.85e-0613419176d97fa07f55ae20c17b9d5262e893957cccc6dba
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A C2CD4B TTC28 KIF1A DYNC2H1 PAPSS2 MADD TNKS2

2.08e-0619519183e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP2 C2CD4B LAMC3 GAL3ST2 RASEF PPP1R36 CDH3

7.95e-061671917cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP2 C2CD4B LAMC3 GAL3ST2 RASEF PPP1R36 CDH3

8.59e-06169191730141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP2 C2CD4B LAIR1 GAL3ST2 GRHL2 RASEF PPP1R36

8.93e-061701917a121e10099faaeb60251eec162f38caf7c4238c2
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B LAIR1 LAMC3 CCDC88B GRHL2 BMPR2 AATK

1.12e-0517619175e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B LAIR1 LAMC3 CCDC88B GRHL2 BMPR2 AATK

1.16e-05177191714fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCellAT1_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

WFS1 SPTBN1 LAMC3 PAPSS2 RANBP17 AATK ANKRD33B

1.29e-051801917ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA6C DCHS2 CORT PXDC1 ARHGAP6 PCDH8

1.32e-051201916a4e3f9a83bc52ccc75bcd64b1be4e2c5441f6d1a
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

COL6A2 DCHS2 CNTNAP1 LAMC3 OLFML3 HMCN2 SNAP25

1.34e-05181191735c470988a93381eefa300831aabb813fa1b90bd
ToppCell21-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

COL6A2 DCHS2 PI16 LAMA4 OLFML3 CNTNAP4 RCN3

1.39e-051821917354dcdb01360597f68c4fe157a682aee1c0b8bb1
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

CACNA1A PPP1R12A LAMA4 ARHGAP6 HMCN2 ROCK1 MYH15

1.44e-051831917818fd886e0188091310825f9145fa53328f2c979
ToppCellPosterior_cortex-Neuronal-Excitatory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CACNA1E SPTBN2 ACTR3B SBNO1 SNAP25 CALN1 RASAL1

1.49e-05184191725ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

DCHS2 SPTBN2 TBC1D2 C2CD4A MYH14 AHNAK2 DOP1B

1.49e-051841917d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HAUS5 WDR81 TRANK1 PPM1F CEP250 SNAP25 MED12

1.77e-051891917bccb3481ffed597c845fe860da658505316105b5
ToppCellfacs-Pancreas-Endocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TTC28 WFS1 C2CD4A PAPSS2 MADD SNAP25

1.77e-051891917010fdd70e9d0e21b856306a29ff877776a480319
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A CACNA1E SPTBN2 RTN1 MADD TRANK1 SNAP25

2.03e-051931917be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A CACNA1E SPTBN2 RTN1 MADD TRANK1 SNAP25

2.03e-0519319170c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A CACNA1E SPTBN2 RTN1 MADD TRANK1 SNAP25

2.03e-0519319178689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TTC28 KIF1A WFS1 PAPSS2 SNAP25 RAB3A

2.10e-051941917490645bfe9ed3dac03c191c7094df01c780b377e
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TTC28 KIF1A WFS1 PAPSS2 MADD SNAP25

2.10e-0519419170b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TTC28 KIF1A WFS1 PAPSS2 MADD PACC1

2.17e-051951917bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PI16 LAMA4 OLFML3 CILP2 RCN3 AHNAK2

2.17e-05195191747762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TTC28 WFS1 PAPSS2 MADD PACC1 RAB3A

2.17e-05195191758b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A C2CD4B TTC28 KIF1A DYNC2H1 PAPSS2 MADD

2.17e-0519519177796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA2 KIF1A BCAN BCL2 AATK DHH PCDH9

2.24e-051961917b6226163d9fc93ecfff2115bb74408303a000490
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA4 BCL2 PCDH17 AATK DHH ANKRD33B PCDH9

2.31e-0519719175c88a97e8e23a5cd61885acbe1ef339ae6a1e35a
ToppCellTracheal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA4 BCL2 PCDH17 AATK DHH ANKRD33B PCDH9

2.31e-051971917c1b2a3fbd5f4aeb3555d8c372efc86f1052e7c65
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

C2CD4B SPTBN2 TBC1D2 C2CD4A MYH14 AHNAK2

3.43e-05142191643524c10f446c9da079cff52800326a1d4675452
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DPP4 ARHGEF18 GAL3ST2 ESRP2 CDH3 AHNAK2

5.40e-0515419168dc8f02534c3ebda30bf9e702e36d0c53d89e5a5
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DPP4 PXDC1 BTBD2 ARHGAP6 CABP4 RGS9BP

5.59e-051551916583cfaa41c755c63aee312eb442e9d97f645d5f7
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TTC28 OBSL1 C2CD4A PCDH17 RANBP17 MED12

5.59e-051551916d10cf5e922dbd3ca46660404da5aca43f181fc19
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C|PND01-03-samps / Age Group, Lineage, Cell class and subclass

INHBB RTN1 PCDH17 PPM1F ANKRD33B RCN3

5.80e-0515619166c8f442ed94ae31e6832b68137e98ae78091ac6c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP4 DCHS2 ABCA12 LAMC3 SPTBN5 RASEF

8.18e-051661916739dfbe927f409821ff23aca6e47ebe78f57e859
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAN2B1 LAIR1 CCDC88B RTN1 MYO1F PACC1

9.02e-051691916b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPP4 CYP8B1 GAL3ST2 RTN1 RAB30 RGS9BP

9.02e-051691916b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAN2B1 LAIR1 CCDC88B RTN1 MYO1F PACC1

9.02e-0516919162322f03a115c662f808ebfc892192b7d38d48181
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ODAD1 CFAP74 CROCC PZP DNAH6

9.02e-05169191614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP4 DCHS2 ABCA12 LAMC3 SPTBN5 RASEF

9.32e-05170191684d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHX16 TAF1C BCL2 PRAG1 PARP10 CEP250

9.63e-0517119162e7cc311005958af52f39ca6c310c85b43a85aaf
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHX16 TAF1C BCL2 PRAG1 PARP10 CEP250

9.63e-0517119164b599f953c8e5b947b2c8bbbf7fe6f9dc388e336
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A C2CD4B KIF1A RTN1 SNAP25 VWA5B1

1.03e-04173191607798461d12d04f3dabff03481c999cb07c5af2f
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell|TCGA-Thryoid / Sample_Type by Project: Shred V9

DCHS2 C2CD4B SPTBN2 TBC1D2 C2CD4A AHNAK2

1.03e-0417319162e9dc137f3675eee07f941eb4cfcaf24a83ab0fb
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-5|TCGA-Pancreas / Sample_Type by Project: Shred V9

SPTBN2 TBC1D2 CABP4 PLEC CDH3 AHNAK2

1.06e-04174191673e1ad4007d94fca25ed7c6fbe5d205d4e1b8a3b
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 GAL3ST2 CABP4 RAB30 SPRED1 RASAL1

1.09e-04175191691cb819a1786020713b7e64480de0545380daae9
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1B CACNA1E KIF1A SPTBN2 SNAP25 VWA5B1

1.09e-0417519168362a46f5804333baa84cd56d450bc147f372a7e
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1B CACNA1E KIF1A SPTBN2 SNAP25 VWA5B1

1.09e-0417519168b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CLCC1 TNRC18 USP32 WDR13 PCDH9 RBM34

1.09e-041751916334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDR81 TNRC18 AATK TRANK1 MMS19 WDR13

1.09e-041751916bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CLCC1 TNRC18 USP32 WDR13 PCDH9 RBM34

1.09e-041751916da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP2 C2CD4B GAL3ST2 GRHL2 RASEF PPP1R36

1.09e-041751916f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E MAN2B1 CYP8B1 CCDC88B MYO1F FKBPL

1.20e-041781916ee674e379ee57e40eb2560ff5ed4c13d8db7ed9d
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 CCDC8 KIF1A PI16 AATK DHH

1.20e-0417819165cf12927f0756c4d8a289fe4308d736382e6212e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E MAN2B1 CYP8B1 CCDC88B MYO1F FKBPL

1.20e-0417819166c45bf197d6c1be0ef7d3a644c0062acf1e24e4d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E MAN2B1 CYP8B1 CCDC88B MYO1F FKBPL

1.20e-041781916cd85dcefe94ee742db64b63e105e13532321894a
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A2 PI16 OLFML3 HMCN2 RCN3 AHNAK2

1.31e-0418119163462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A2 PI16 OLFML3 HMCN2 RCN3 AHNAK2

1.31e-0418119166730e249cac55ae892cc567d9211615882f3dab4
ToppCellRV|World / Chamber and Cluster_Paper

TRPM7 OBSCN LAMA4 MICAL3 MYOM2 HOOK2

1.31e-041811916bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 OBSCN TRANK1 CNTNAP4 MYH15 MYOM2

1.44e-0418419162cbed6462fea2622871bb7e49b0df3d984239281
ToppCellwk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CACNA1A CACNA1B KIF1A INHBB SPTBN2 CALN1

1.44e-0418419169e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 OBSCN TRANK1 CNTNAP4 MYH15 MYOM2

1.44e-041841916ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellwk_08-11-Epithelial-PNS-PCP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CACNA1B KIF1A SPTBN2 RTN1 CILP2 SNAP25

1.44e-041841916eac2a9089913f33a961ba11519b53645790f2056
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 OBSCN TRANK1 CNTNAP4 MYH15 MYOM2

1.44e-0418419162b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A DPP4 TTC28 PI16 BCL2 TMEM191B

1.48e-041851916e34473eea3a58c041183a4f52137366cd9489495
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL DYNC2H1 ODAD1 CFAP74 PZP DNAH6

1.48e-0418519165e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B CACNA1E KIF1A RTN1 SNAP25 RAB3A

1.48e-041851916110d5f02759c8235b14aea524ea47199696094ea
ToppCellwk_15-18-Epithelial-PNS-MFNG+_DBH+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLC24A5 KIF1A SPTBN2 GAL3ST2 SNAP25 PCDH8

1.52e-04186191672f7427d62d65e37bb0bf99229a1b75df081a128
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CNTLN CNTNAP4 ROCK1 MYH15 PLEC CALN1

1.52e-04186191623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

INHBB LAMA4 C2CD4A PCDH17 HMCN2 DHH

1.52e-0418619162e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

INHBB LAMA4 C2CD4A PCDH17 HMCN2 DHH

1.52e-041861916c3449e54454009973818fc1101933c6f0168258c
ToppCellImmune-B_cell|World / Lineage, Cell type, age group and donor

BCL2 RAB30 MICAL3 ANKRD33B PCDH9 RASAL1

1.57e-041871916795690c6306c366e733279491138d0cd9b469b21
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A CNTNAP1 RTN1 SNAP25 RAB3A CALN1

1.57e-0418719161b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A COL6A2 TTC28 MYO1F PZP PCDH9

1.57e-041871916cfdc1585c80d2bb475d9145395fb50a88c53f838
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

TTC28 PAPSS2 PCDH17 BMPR2 DHH CALN1

1.57e-04187191681affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TBC1D2 PRAG1 GRHL2 RANBP17 MYH14 RASEF

1.61e-041881916eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B CACNA1E KIF1A RTN1 SNAP25 RAB3A

1.61e-041881916bd091503f580dedab40e0996273101285d24b586
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

NRIP2 WDR81 PRAG1 CILP2 HMCN2 DHH

1.61e-041881916c90669b51e1902fe7726555290c91c92a911df83
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CACNA1B CACNA1E TRANK1 CNTNAP4 SNAP25 PCDH8

1.61e-041881916b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TTC28 KIF1A C2CD4A PAPSS2 MADD

1.61e-041881916a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCelldroplet-Lung-1m-Epithelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C2CD4B TTC36 MYH14 RASEF PPP1R36 DNAH6

1.66e-04189191672ecd5a10e419bac475e22f5b602e7f008835ce9
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

TRPM7 OBSCN MICAL3 MYOM2 HOOK2 MYO18B

1.66e-0418919165e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI16 SPTBN2 CNTNAP1 RTN1 SNAP25 CALN1

1.66e-0418919163d838da870623a6a278ddc8e6cedca85d9877e50
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SPTBN2 CNTNAP1 RTN1 SNAP25 CALN1

1.66e-041891916f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellHippocampus-Neuronal-Excitatory|Hippocampus / BrainAtlas - Mouse McCarroll V32

CACNA1E ACTR3B SBNO1 ANKRD33B CALN1 RASAL1

1.66e-0418919164b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 OBSL1 MYOM2 MYO18B PCDH9 RCN3

1.71e-04190191696a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP2 RBM11 CCDC8 SPTBN2 SNAP25 VWA5B1

1.76e-041911916501d4f6ad389d9ac5051d4247b9bd3da96f713f9
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP2 COL6A2 PI16 INHBB LAMA4 RCN3

1.76e-041911916b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

COL6A2 LAMA4 LAMC3 BCL2 ARHGAP6 ANKRD33B

1.76e-04191191678c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellfacs-Lung-EPCAM-24m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP2 RBM11 CCDC8 SPTBN2 SNAP25 VWA5B1

1.76e-0419119168e06cc61eaff1796c2ce014074029408ba88d561
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 COL6A2 PI16 OLFML3 CILP2 RCN3

1.76e-0419119161b26056df078674f37a6c06f6256b30cfcec21a7
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 PI16 INHBB LAMA4 OLFML3 RCN3

1.81e-041921916671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PI16 LAMA4 OLFML3 CILP2 RCN3

1.81e-041921916f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

TRPM7 OBSCN MICAL3 MYOM2 HOOK2 MYO18B

1.81e-041921916ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A2 TTC28 LAMA4 BCL2 ARHGAP6 PZP

1.81e-041921916162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
Drugdithiotreitol

CERKL HK1 TRPM7 SPTBN1 SPTBN2 RDH14 LAMA4 LAMC3 GAL3ST2 PAPSS2 PAPSS1 SPTBN5 PARP10 PPP3CC NKPD1 USP39 TNKS2

1.34e-0743019017CID000019001
DrugIsoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; HL60; HG-U133A

ARID4A OBSL1 PCDH17 ARHGAP4 AATK TRANK1 TJAP1 PACC1 PLEC WDR13 MED12

9.14e-07198190111985_UP
DrugAC 110

CACNA1A CACNA1B CACNA1E

2.27e-0641903CID000022860
DrugPRODAN

SPTBN1 SPTBN2 SPTBN5 NKPD1

5.97e-06151904CID000028127
DrugSulfinpyrazone [57-96-5]; Up 200; 9.8uM; HL60; HG-U133A

TTC28 LAIR1 SPART MOSPD3 ACTR3B MYH14 PI4KA ACIN1 HOOK2 MED12

6.75e-06198190101574_UP
DrugLobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; HL60; HG-U133A

TTC28 CNTNAP1 LAIR1 OBSL1 ARHGEF11 SLC6A3 TSR1 PPM1F WDR13 DOP1B

7.06e-06199190101747_UP
Drug3,4-dihydroquinazoline

CACNA1A CACNA1B CACNA1E

1.12e-0561903CID000583065
Drugalpha-sialylcholesterol

CACNA1A CACNA1B CACNA1E

1.12e-0561903CID000133976
DrugAPMPA

CACNA1A CACNA1B CACNA1E

1.95e-0571903CID000512300
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

EFCAB11 GAMT KIF1A CNTNAP1 ARHGAP4 MYH14 PPM1F CEP250 MED12

3.99e-0519519096967_UP
DrugUrsolic acid [77-52-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A

ABCA2 KIF1A HAUS5 ACTR3B ARHGEF11 ACIN1 PLEC WDR13 MED12

4.15e-0519619097181_DN
DrugEthotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A

DPP4 TAF1C SPTBN1 SPTBN2 TBC1D2 ARHGEF11 ARHGAP4 RAB30 RCN3

4.15e-0519619094366_DN
DrugFurazolidone [67-45-8]; Down 200; 17.8uM; HL60; HT_HG-U133A

CACNA1A EFCAB11 KIF1A DYNC2H1 TAF1C ARHGEF11 STAT5A MYH15 SNAP25

4.32e-0519719093019_DN
DrugLY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A

KIF1A HAUS5 ARHGEF11 BMPR2 PPP3CC PPM1F NUP160 MED12 DOP1B

4.32e-0519719096935_DN
DrugAconitine [302-27-2]; Down 200; 6.2uM; PC3; HT_HG-U133A

COL6A2 CNTNAP1 HAUS5 BTBD2 ESRP2 RBM6 HOOK2 RAB3A DOP1B

4.32e-0519719097149_DN
DrugTrichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A

GAMT ABCA12 SMC1A TAF1C SPTBN2 TBC1D2 ARHGEF11 RAB30 RCN3

4.32e-0519719093337_DN
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

SPTBN1 OBSL1 SPART BCAN SPTBN5 ARHGAP4 TRANK1 AHNAK2 DOP1B

4.32e-0519719092328_UP
DrugAmrinone [60719-84-8]; Down 200; 21.4uM; HL60; HT_HG-U133A

SMC1A ACTR3B ARHGEF11 PAPSS2 BMPR2 PACC1 MICAL3 PCDH9 RCN3

4.49e-0519819092724_DN
DrugTetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; HL60; HT_HG-U133A

EFCAB11 PXDC1 SPTBN1 CNTNAP1 BCL2 GRHL2 ESRP2 MYH14 PCDH9

4.49e-0519819092489_UP
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

CACNA1A DPP4 SPART BCAN ARHGEF11 SPTBN5 TRANK1 TJAP1 AHNAK2

4.67e-0519919092329_UP
DrugPraziquantel [55268-74-1]; Up 200; 12.8uM; HL60; HG-U133A

TAF1C HAUS5 LAIR1 DIDO1 HOOK2 TNKS2 WDR13 MED12 RASAL1

4.67e-0519919091572_UP
DrugMethocarbamol [532-03-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A

GAMT TAF1C HAUS5 TBC1D2 BCAN RAB30 TJAP1 MICAL3 PCDH9

4.67e-0519919097467_UP
Drugaristolactam AII

CACNA1B CACNA1E

6.93e-0521902CID000148657
Drugalkosin

CACNA1B CACNA1E

6.93e-0521902CID005488638
Drugadenosine 5'-phosphoselenate

PAPSS2 PAPSS1

6.93e-0521902CID000440758
Drugnorcepharadione B

CACNA1B CACNA1E

6.93e-0521902CID000189168
Drugpiperolactam A

CACNA1B CACNA1E

6.93e-0521902CID003081016
Drugbeta-methylene-APS

PAPSS2 PAPSS1

6.93e-0521902CID000129324
Drugeniluracil

CACNA1A CACNA1B CACNA1E CDH3

7.10e-05271904CID000043157
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

2.35e-0731833DOID:0111181 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

9.34e-0741833DOID:6364 (implicated_via_orthology)
DiseaseGlobal developmental delay

CACNA1B CACNA1E HK1 SPTBN2 SPART GTF3C3 PRR12 AP2M1

1.90e-061331838C0557874
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

8.06e-0671833DOID:0050951 (implicated_via_orthology)
Disease3-M syndrome

CCDC8 OBSL1

1.14e-0431832cv:C1848862
Disease3-M syndrome (is_implicated_in)

CCDC8 OBSL1

1.14e-0431832DOID:0060241 (is_implicated_in)
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTBN1 SPTBN2

2.28e-0441832DOID:0050882 (implicated_via_orthology)
Diseaseapolipoprotein B measurement

DCHS2 DNAJC13 HK1 WDR81 C2CD4A HS1BP3 MOSPD3 CLCC1 PARP10 CILP2 FER1L4 NKPD1 PLEC

2.72e-0466318313EFO_0004615
Diseaseserum albumin measurement

DNAJC13 WDR81 BCL2 MADD PRR12 PARP10 CILP2 SBNO1 ALDH16A1 MICAL3 PLEC RCN3

3.47e-0459218312EFO_0004535
Diseaseleprosy

ACTR3B CCDC88B PRMT6 MYH15 CROCC

4.65e-041031835EFO_0001054
DiseaseAtaxia

CACNA1A HK1 AP2M1

4.88e-04251833C0004134
DiseaseIntellectual Disability

CACNA1B CACNA1E HK1 GAMT PPP1R12A GTF3C3 SLC6A3 PRR12 AP2M1 ACIN1

5.09e-0444718310C3714756
DiseaseAutosomal dominant nonsyndromic hearing loss

WFS1 GRHL2 MYH14

7.61e-04291833cv:C5779548
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP1 CNTNAP4

1.05e-0381832DOID:0060308 (implicated_via_orthology)
DiseaseNonsyndromic genetic hearing loss

WFS1 TRIOBP GRHL2 MYH14

1.30e-03761834cv:C5680182
Diseasepost-traumatic stress disorder (biomarker_via_orthology)

WFS1 BCL2

1.34e-0391832DOID:2055 (biomarker_via_orthology)
Diseasehair colour measurement, eye colour measurement, skin pigmentation measurement

SLC24A5 HERC2

1.67e-03101832EFO_0007009, EFO_0007822, EFO_0009764
Diseasecognitive function measurement, self reported educational attainment

CACNA1E TRIOBP PCDH17 PRR12 CNTNAP4 MYH15 NUP160 CALN1

1.76e-033551838EFO_0004784, EFO_0008354
Diseaseretinitis pigmentosa (is_implicated_in)

CERKL HK1 ARHGEF18

2.10e-03411833DOID:10584 (is_implicated_in)
DiseaseDisorder of eye

SLC24A5 CERKL WFS1 CABP4 RGS9BP CDH3

2.15e-032121836C0015397
DiseaseHereditary hearing loss and deafness

WFS1 TRIOBP GRHL2 BCS1L MYH14

2.22e-031461835cv:C0236038
DiseaseDepressive disorder

DPP4 WFS1 BCL2 SLC6A3 PPP3CC SNAP25 MED12

2.26e-032891837C0011581
Diseaseeye color

SLC24A5 HK1 TRANK1 HERC2

2.42e-03901834EFO_0003949
Diseaseintracranial aneurysm (is_implicated_in)

BCL2 PKD1

2.42e-03121832DOID:10941 (is_implicated_in)
DiseaseSeizures

CACNA1B CACNA1E GAMT SMC1A GTF3C3 AP2M1

2.47e-032181836C0036572
Diseaseautism spectrum disorder (implicated_via_orthology)

CNTNAP1 LAMC3 SLC6A3 CNTNAP4 LRBA

2.64e-031521835DOID:0060041 (implicated_via_orthology)
DiseaseDiabetes Mellitus, Non-Insulin-Dependent

C2CD4B HK1 WFS1 C2CD4A BCL2 SNAP25

2.64e-032211836C0011860
Diseaseovarian serous carcinoma

TTC28 LAMA4 RAB33B

2.93e-03461833EFO_1001516
DiseaseMalignant neoplasm of breast

DYNC2H1 PXDC1 OBSCN BCL2 STAT5A SLC6A3 BMPR2 SBNO1 PPM1F FKBPL PACC1 LRBA HERC2 PCDH8 MED12

2.96e-03107418315C0006142
Diseasehearing impairment

WFS1 TRIOBP GRHL2 HSD17B4

3.29e-03981834C1384666
Diseaseunipolar depression

CACNA1E DYNC2H1 CNTNAP1 NVL YTHDC2 CNTLN ACTR3B PCMTD1 RTN1 CLCC1 AREL1 PKD1 PZP DNAH6 PCDH9 MED12

3.57e-03120618316EFO_0003761
DiseaseSchizophrenia

CACNA1B HK1 EFCAB11 SPTBN2 BCL2 ARHGEF11 PCDH17 SLC6A3 PPP3CC SBNO1 PI4KA PCDH8 MED12

3.58e-0388318313C0036341
Diseasehigh grade glioma (biomarker_via_orthology)

BCAN SLC6A3

3.81e-03151832DOID:3070 (biomarker_via_orthology)
Diseasenervousness

MADD NUP160

4.34e-03161832NCIT_C74532
Diseaselower face morphology measurement

DCHS2 YTHDC2 PRAG1 MYOM2

4.80e-031091834EFO_0010948
Diseasefibrinogen measurement

DCHS2 PRR12 PARP10 PLEC

4.80e-031091834EFO_0004623
DiseaseMental Depression

DPP4 WFS1 SLC6A3 PPP3CC SNAP25 MED12

5.20e-032541836C0011570
DiseaseNuclear non-senile cataract

WFS1 FYCO1

5.48e-03181832C1112705
DiseaseNuclear cataract

WFS1 FYCO1

5.48e-03181832C0392557
DiseaseR-6-hydroxywarfarin measurement

RBM15 SELENOO LRBA PCDH9

5.62e-031141834EFO_0803327
Diseaseneutrophil count

SEMA6C CACNA1A DNAJC13 TTC28 DYNC2H1 CYP8B1 SPTBN1 BCL2 LRRC52 AATK SBNO1 CLEC4G PKD1 LRBA TNKS2 FBXL20 NUP160

5.70e-03138218317EFO_0004833
Diseaseelectrocardiography

PXDC1 SPTBN1 OBSCN YTHDC2 TRANK1 HMCN2 RBM6 PLEC MYO18B

6.05e-035301839EFO_0004327
DiseasePROSTATE CANCER, HEREDITARY, 1

TTC28 BCL2 ARHGAP6

6.20e-03601833C4722327

Protein segments in the cluster

PeptideGeneStartEntry
ERGRRGENLFAITDE

PI16

81

Q6UXB8
TRSQEQEVLERGGRF

ACIN1

326

Q9UKV3
QEVLERGGRFTRSQE

ACIN1

331

Q9UKV3
GEFAKERERVENRRA

CACNA1A

361

O00555
ERRQESLEEGSDRNY

ARHGEF18

511

Q6ZSZ5
VRVDRFGRDVNFTLD

CNTNAP1

266

P78357
IGEEAREVARRQEGA

CORT

66

O00230
VVFDDGDERTLRRTS

ARID4A

91

P29374
EGSRLRAQSEAAEER

CCDC88B

831

A6NC98
SGEFAKERERVENRR

CACNA1E

351

Q15878
CVAERREEQLFRSGE

CNTLN

656

Q9NXG0
VTGRAVREVRDGDVQ

ALDH16A1

126

Q8IZ83
RLRVESGAAEFDLVQ

ABCA12

2241

Q86UK0
GLADRIVRDVQEFID

BCS1L

196

Q9Y276
QAQRRVLRGVDDLDF

ACTR3B

46

Q9P1U1
EIDSRLRNSEDARGV

ARHGEF11

386

O15085
IEALNFREERARDVA

ANKRD45

136

Q5TZF3
EEGVVFIEIDDNRRR

CNTNAP4

1111

Q9C0A0
DFDGRVLTEAAQVRV

FAM187A

81

A6NFU0
LVSVDEADYEAGRRR

DEDD2

296

Q8WXF8
RFRAALEEVEGDVAE

ACAP2

16

Q15057
RLQDLEERDAFAERV

DHX16

171

O60231
VRDLAREYRAAGEQE

DHX16

276

O60231
DRDIFIDGVVARNRA

DIS3L2

91

Q8IYB7
DEIREAFRVLDRDGN

CALN1

81

Q9BXU9
SGEFAKERERVENRR

CACNA1B

356

Q00975
RRGVSVEEAQETDRN

ANKRD33B

106

A6NCL7
ARDERRFRVADQDGD

RCN3

166

Q96D15
VLRDRGLAADERAEF

RGS9BP

61

Q6ZS82
SRVRDFLDRLVDVDG

RASAL1

536

O95294
RRDVAEALRSDGNTE

RANBP17

1066

Q9H2T7
EEADRTVFVGNLEAR

RBM11

6

P57052
RRAFDRFGVITEVDI

RBM15

391

Q96T37
RTEATIGVDFRERAV

RAB33B

61

Q9H082
RIREEGTDLEVTANR

PZP

321

P20742
QIADGFRIRVDLASE

RBM34

266

P42696
ARAGQIRYSVREEID

PCDHGA2

26

Q9Y5H1
RDLGRESVDAEEVVR

PCDH17

1126

O14917
LAERREVSQQRAEEF

RAB30

126

Q15771
DERVVSSERGRQLAD

RAB3A

141

P20336
DANRSGRLEREEFRA

RASEF

21

Q8IZ41
DTISGRVDRLEREVD

OLFML3

81

Q9NRN5
VGESERAVRQVFQRA

NVL

656

O15381
FLRRLQDVRAEEGQD

OBSL1

1451

O75147
EGDSSEDRAFRVRIA

BCAN

26

Q96GW7
FSPGDREENIRRIAE

PAPSS2

91

O95340
VEERQRRLEERGVAV

MICAL3

1861

Q7RTP6
GIVEERRTVVDSEGR

HAX1

221

O00165
VDRRQAEIGEGSVRR

MADD

751

Q8WXG6
AERRARERQGASFAE

LZTS3

586

O60299
ELREELGEAAAAFRV

NUDT16

76

Q96DE0
VFGRFDETVIEERRQ

RPS6KC1

86

Q96S38
EGLRVEFDRQCSTER

HERC2

3636

O95714
RREVFQTASERVEAE

MMS19

306

Q96T76
TERERGRTAAEDNVR

FYCO1

276

Q9BQS8
EAGEARRNFSVEVLV

HMCN2

2436

Q8NDA2
ENFRLESGREDERLR

HOOK2

251

Q96ED9
VIDLGGSREERREAF

DOP1B

736

Q9Y3R5
LTEAIQALFERGERR

INHBB

231

P09529
ESEARFRIDSVREGN

LAIR1

81

Q6GTX8
QDVLFSVVEEERGRD

FER1L4

681

A9Z1Z3
FDGLSEDEVRRLAVR

C2CD4B

321

A6NLJ0
REQLEEEAAARERAG

MYH14

1366

Q7Z406
EEAAARERAGRELQT

MYH14

1371

Q7Z406
VLRAVEERERAEAEG

MYH14

1481

Q7Z406
TVRQVFRLEEGVASD

MYH14

1956

Q7Z406
TERVEQAFRAIDRGD

PCMTD1

26

Q96MG8
RQDTYELDVRAQDRG

PCDH8

316

O95206
DREEQERFIFTVTAR

PCDH9

531

Q9HC56
RSELRRFQDGAIREA

NOL6

586

Q9H6R4
GIFQLDERRRDAVIA

PI4KA

66

P42356
EELEGVRRRSFNDFR

PI4KA

221

P42356
DINRLRAVVFRDIED

LRBA

1511

P50851
RRRVETILEENVDGT

LKAAEAR1

176

Q8TD35
DEAGTRVEVSRRIFQ

LRRC52

286

Q8N7C0
GTVRVDRRVARGEEQ

MED12

1706

Q93074
RRLGTFEVEDQIEAA

DPP4

596

P27487
RDDIGRNAVDAFRVN

AP2M1

21

Q96CW1
VEEVERRVLGSSERQ

HAUS5

326

O94927
EDIRTEFDREIDRGS

HK1

271

P19367
EAERLEARFQDVRGQ

ODAD1

356

Q96M63
DGREAVEFRQETSVV

PACC1

251

Q9H813
EFVTRVEALDRDSGV

DCHS2

1741

Q6V1P9
RVGEDSVDFRLRVSE

OBSCN

871

Q5VST9
VRQLREEFDRGIDVS

ARHGAP6

441

O43182
FSPEDREENVRRIAE

PAPSS1

101

O43252
EEGYVRARIAEVERR

GAL3ST2

206

Q9H3Q3
RGVREDIATFDARNI

DYNC2H1

3041

Q8NCM8
EQEDAVQDGARVRRE

CROCC

646

Q5TZA2
IRLAEVTERLGEFRN

DNAH6

351

Q9C0G6
REERARGTELFRAGN

FKBPL

211

Q9UIM3
RGDGEEQRVVIFEQT

GRHL2

176

Q6ISB3
GESDIRERRAVFNEI

HS1BP3

101

Q53T59
GAEEIRGLERQVRAE

COG1

26

Q8WTW3
REFDRDRDGRITVAE

CABP4

216

P57796
ARVARVAREEAVGVF

DHH

311

O43323
GILRDRSFARISDED

HSD17B4

101

P51659
EQARRLEEELAVEGR

CEP250

1866

Q9BV73
QAERAREEGIRLFAV

COL6A2

176

P12110
NIARFIVGDERVTAD

BMPR2

256

Q13873
AFDTQLVERGRRHEV

DIDO1

1396

Q9BTC0
VDVASERQRVLRGDA

ABCA2

2031

Q9BZC7
SFLQNEDRERRGDRT

AREL1

31

O15033
REVVRFNGLEDRVHV

PRMT6

121

Q96LA8
RRNRVSALEGGREEE

CERKL

6

Q49MI3
RRENGLEVLQEAFSR

DNAJC13

1441

O75165
QEVVRDLVRQGRLEF

MAN2B1

136

O00754
ALLEAGFRRENIRTE

GAMT

196

Q14353
GEDAVVFTIDLRQDR

DCAF8L1

306

A6NGE4
ERDTLGIREVRLFNA

BTBD2

271

Q9BX70
EFRERLTQFLEEEGR

CCDC8

36

Q9H0W5
EDAVQDGVRVRRELE

CROCCP3

111

Q8IVE0
TVLEVFREVDRDSDG

EFCAB11

131

Q9BUY7
RQEEASVRGREKAER

PPP1R18

16

Q6NYC8
REFSDFIQAVERRGV

SBNO1

501

A3KN83
FDGLSEDEVRRLAVR

C2CD4A

326

Q8NCU7
DDFTVRNGETVQERR

CDH3

71

P22223
TAVGTLDREDEQFVR

CDH3

496

P22223
QEGRLEAFRTADREE

CFAP74

176

Q9C0B2
ADREEVEATGRRLQV

CFAP74

186

Q9C0B2
RAVREEATQVLGEAR

CYP8B1

306

Q9UNU6
TRVGREDGERRQDIV

KIF1A

516

Q12756
AAQADVRVFEELRGL

PKD1

1201

P98161
DPEGALREAFRRTDQ

PPM1F

226

P49593
ERLAENTGEFQEVVR

PARP10

821

Q53GL7
FTRVDRDVEVEDFQR

LAMA4

1376

Q16363
EARRDEGEARTRGQE

NRIP2

56

Q9BQI9
DAIREETGVRAEERA

RTN1

496

Q16799
RGRDLSDLDFRAREQ

RBM6

196

P78332
RGAREFVEREVIDFA

MRPL43

41

Q8N983
RLIVSRRGDEEEFFE

PXDC1

26

Q5TGL8
REVRAKNGRVDSEDR

USP39

86

Q53GS9
GETEENVRRVFQRAR

SPATA5L1

276

Q9BVQ7
LQGEAREAARERAER

TMEM191B

111

P0C7N4
LQGEAREAARERAER

TMEM191C

111

A6NGB0
EDELEEVGARRAAQR

AATK

661

Q6ZMQ8
ERGQGRIDDEAARRI

NKPD1

361

Q17RQ9
RIDDEAARRIQEALF

NKPD1

366

Q17RQ9
STELRREEEEGQRLG

TAF1C

666

Q15572
RVSFGVDEEERVRVL

CHCHD6

11

Q9BRQ6
GELEGEIRRSAEAQR

MYH15

1836

Q9Y2K3
QRIDLFDFQRDIEGR

FBXL20

66

Q96IG2
FDFQRDIEGRVVENI

FBXL20

71

Q96IG2
AGRRSEAEEEEARTI

RNF26

331

Q9BY78
EAAERGDFSEVRRVL

SELENOO

606

Q9BVL4
FADAAGAREVVQVRE

SLC26A10

476

Q8NG04
AEREGATEEAVRERV

MRI1

111

Q9BV20
VDEAVPRVRFANDDR

WDR13

171

Q9H1Z4
DRARAEEAAGQLRRE

RDH14

76

Q9HBH5
RRNGEALIRFVDSEQ

ESRP2

296

Q9H6T0
EGIFRERDEFVIRAE

PRR12

1571

Q9ULL5
LERSFVELSGAERER

NUP160

41

Q12769
EEAERRGQIYDRQGA

SUV39H1

281

O43463
EVERLFGQERRKSEA

TRIOBP

1306

Q9H2D6
REAERQEEKRAGRSV

ARHGAP4

186

P98171
GAQLRVSEIRDAFER

ARHGAP4

546

P98171
AFAAELRRLEEQGRA

SPTBN5

796

Q9NRC6
GGFIRRVTNDARENE

SNAP25

131

P60880
REFARDTGNIGQERV

SPTBN1

1741

Q01082
RADRRGAESVTEEKF

STAT5A

426

P42229
ANIRFARGEREEAIL

GTF3C3

156

Q9Y5Q9
ARGRFATVVEELFRD

BCL2

126

P10415
AATGSRREERAEQDR

AHNAK2

371

Q8IVF2
RVRREERVFLVGNVE

CILP2

706

Q8IUL8
ERVFLVGNVEIRERR

CILP2

711

Q8IUL8
EAGRGREDVRTELFR

CLEC4G

136

Q6UXB4
EILRERDVDLRFQTG

CLCC1

421

Q96S66
ERRELAVEQGERALE

ZBED3

151

Q96IU2
RRTEALERELEIGQD

TJAP1

61

Q5JTD0
IRSFEEARGLDRINE

PPP3CC

461

P48454
RGVVDLTQEARAEGR

TNRC18

236

O15417
RAEEENEFQIPGRTR

SPART

341

Q8N0X7
DEVDTPRDVAARIRF

TSR1

486

Q2NL82
RREESLGEARRLQDF

SPTBN2

1056

O15020
AFDRGIRRAIEDISQ

SPRED1

111

Q7Z699
RELVDRGEVRQFTLR

SLC6A3

601

Q01959
RFRIELSEEGAEGRV

MOSPD3

111

O75425
RQRRSELGIELFEEN

ZHX1

821

Q9UKY1
EDEGQPFIRRQSRTD

SLC24A5

251

Q71RS6
CREIGVRNIREFEEE

SMC1A

781

Q14683
REVSVEDARLGRVQF

SEMA6C

241

Q9H3T2
FRRQHLTEIEEEVGR

PPP1R36

251

Q96LQ0
VGNEDTVSRLEVFAR

RFC2

51

P35250
AEREARRRGKAEEQA

PLEC

1806

Q15149
IIDRRSGRQYDIDDA

PLEC

4331

Q15149
FAEKAVDRRRGVELE

PRAG1

1366

Q86YV5
RELFEACRNGDVERV

TNKS2

26

Q9H2K2
ESERAERLQAFREVQ

MYO18B

1461

Q8IUG5
FLTDREVRLGRNGVE

ROCK1

316

Q13464
DEALAVAERGRTRAF

TTC28

1186

Q96AY4
VAERVAAERRERIGQ

YTHDC2

256

Q9H6S0
QGRDDDARRDFERAA

TTC36

136

A6NLP5
GFQERVRAQRAVAEE

ZNF622

46

Q969S3
KIFRRRRGDSESEED

C9orf78

6

Q9NZ63
ERVREEAREPRAGNF

TRANK1

2701

O15050
ENEVEDFGELRPRRR

TRANK1

2901

O15050
RRRLQEELNEFVESG

SNRNP48

11

Q6IEG0
SGSEERIRVTFERVE

TRPM7

1191

Q96QT4
FDVDRDGVLSRVELR

USP32

276

Q8NFA0
RVEDEAQGRELVFAL

WDR81

891

Q562E7
ELGRRVEALEQERES

TBC1D2

371

Q9BYX2
ARAIIRDFEQLAERE

VWA5B1

856

Q5TIE3
DRRGITSENEREVRQ

WFS1

151

O76024
EGRVALETQRDLEDR

LAMC3

1196

Q9Y6N6
EEVRERKFDGFARTI

MYO1F

686

O00160
NAAVVVRRFRGDEEP

MYOM2

241

P54296
RQGVDIEAARKEEER

PPP1R12A

161

O14974