Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontryptophan 5-monooxygenase activity

TPH2 TPH1

2.19e-052942GO:0004510
GeneOntologyMolecularFunctionhyaluronan synthase activity

HAS1 HAS2

1.31e-044942GO:0050501
MousePhenoabnormal vertebrae number

HOXA11 DACT1 HOXD11 WNT7A SGO1 ST18

5.78e-0678816MP:0004643
MousePhenoabnormal sacral vertebrae morphology

HOXA11 DACT1 HOXD11 SGO1 ST18

4.52e-0568815MP:0003050
MousePhenoincreased vertebrae number

HOXA11 HOXD11 SGO1 ST18

5.35e-0536814MP:0004644
DomainWnt7

WNT7A WNT7B

2.56e-052952IPR013300
DomainTrp_5_mOase

TPH2 TPH1

2.56e-052952IPR005963
DomainRan_BP1

RANBP2 RGPD8 RGPD5

2.71e-0512953PF00638
DomainRANBD1

RANBP2 RGPD8 RGPD5

2.71e-0512953PS50196
DomainRanBD

RANBP2 RGPD8 RGPD5

3.51e-0513953SM00160
DomainRan_bind_dom

RANBP2 RGPD8 RGPD5

3.51e-0513953IPR000156
DomainACT_dom

TPH2 TPH1

7.65e-053952IPR002912
DomainACT

TPH2 TPH1

7.65e-053952PS51671
DomainDUF3528

HOXA11 HOXD11

7.65e-053952IPR021918
DomainHAS/NodC

HAS1 HAS2

7.65e-053952IPR026107
DomainACT

TPH2 TPH1

7.65e-053952PF01842
DomainDUF3528

HOXA11 HOXD11

7.65e-053952PF12045
Domain-

TPH2 TPH1

1.53e-0449521.10.800.10
DomainArAA_hydroxylase_Fe/CU_BS

TPH2 TPH1

1.53e-044952IPR018301
DomainBH4_AAA_HYDROXYL_2

TPH2 TPH1

1.53e-044952PS51410
DomainArAA_hydroxylase

TPH2 TPH1

1.53e-044952IPR001273
DomainBiopterin_H

TPH2 TPH1

1.53e-044952PF00351
DomainTyrosine_3-monooxygenase-like

TPH2 TPH1

1.53e-044952IPR019773
DomainAromatic-AA_hydroxylase_C

TPH2 TPH1

1.53e-044952IPR019774
DomainBH4_AAA_HYDROXYL_1

TPH2 TPH1

1.53e-044952PS00367
DomainAA_TRANSFER_CLASS_1

GOT1L1 ACCSL

3.79e-046952PS00105
DomainTPR-like_helical_dom

RANBP2 CFAP54 RGPD8 SRP68 TRRAP RGPD5

1.22e-03233956IPR011990
DomainGrip

RGPD8 RGPD5

1.37e-0311952SM00755
DomainGRIP

RGPD8 RGPD5

1.37e-0311952PF01465
DomainGRIP_dom

RGPD8 RGPD5

1.63e-0312952IPR000237
DomainGRIP

RGPD8 RGPD5

1.63e-0312952PS50913
DomainAminotran_1_2

GOT1L1 ACCSL

3.31e-0317952PF00155
DomainAminotransferase_I/II

GOT1L1 ACCSL

3.31e-0317952IPR004839
DomainPTPc_motif

PTPN7 MTMR6 PTPRC

3.37e-0359953SM00404
DomainTyr_Pase_cat

PTPN7 MTMR6 PTPRC

3.37e-0359953IPR003595
Domain-

RANBP2 CFAP54 RGPD8 SRP68 TRRAP

4.12e-032079551.25.40.10
DomainWnt

WNT7A WNT7B

4.14e-0319952IPR005817
DomainWNT1

WNT7A WNT7B

4.14e-0319952PS00246
DomainWnt_CS

WNT7A WNT7B

4.14e-0319952IPR018161
Domainwnt

WNT7A WNT7B

4.14e-0319952PF00110
DomainWNT1

WNT7A WNT7B

4.14e-0319952SM00097
PathwayREACTOME_SEROTONIN_AND_MELATONIN_BIOSYNTHESIS

TPH2 TPH1

2.76e-045752MM14831
PathwayREACTOME_HYALURONAN_BIOSYNTHESIS_AND_EXPORT

HAS1 HAS2

2.76e-045752M27144
PathwayREACTOME_SEROTONIN_AND_MELATONIN_BIOSYNTHESIS

TPH2 TPH1

2.76e-045752M27119
PathwayREACTOME_HYALURONAN_BIOSYNTHESIS_AND_EXPORT

HAS1 HAS2

2.76e-045752MM14865
PathwayKEGG_MEDICUS_REFERENCE_SEROTONIN_METABOLISM

TPH2 TPH1

2.76e-045752M47902
Pubmed

Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.

RANBP2 RGPD8 RGPD5

8.14e-0849639480752
Pubmed

Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney.

HOXA11 HOXD11 WNT7B

7.26e-061496311493536
Pubmed

Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production.

TPH2 TPH1

7.54e-06296220921119
Pubmed

Maternal serotonin is crucial for murine embryonic development.

TPH2 TPH1

7.54e-06296217182745
Pubmed

Coding sequence of a hyaluronan synthase homologue expressed during expansion of the mouse cumulus-oocyte complex.

HAS1 HAS2

7.54e-0629629016821
Pubmed

Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese.

TPH2 TPH1

7.54e-06296217768266
Pubmed

Association between single nucleotide polymorphisms of TPH1 and TPH2 genes, and depressive disorders.

TPH2 TPH1

7.54e-06296229314569
Pubmed

Hyaluronic acid, HAS1, and HAS2 are significantly upregulated during muscle hypertrophy.

HAS1 HAS2

7.54e-06296222785117
Pubmed

Absence of mutations in the HOXA11 and HOXD11 genes in children with congenital renal malformations.

HOXA11 HOXD11

7.54e-06296219255789
Pubmed

TPH2 and TPH1: association of variants and interactions with heroin addiction.

TPH2 TPH1

7.54e-06296218181017
Pubmed

Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis.

TPH2 TPH1

7.54e-06296225005534
Pubmed

Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations.

TPH2 TPH1

7.54e-06296220213726
Pubmed

Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development.

HOXA11 HOXD11

7.54e-06296216581055
Pubmed

Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies.

TPH2 TPH1

7.54e-06296216581041
Pubmed

Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome.

TPH2 TPH1

7.54e-06296221073637
Pubmed

Predominant expression of tryptophan hydroxylase 1 mRNA in the pituitary: a postmortem study in human brain.

TPH2 TPH1

7.54e-06296219233335
Pubmed

Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning.

HOXA11 HOXD11

7.54e-0629628660870
Pubmed

Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.

TPH2 TPH1

7.54e-06296214597720
Pubmed

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.

TPH2 TPH1

7.54e-06296219181488
Pubmed

Family-based association study of TPH1 and TPH2 polymorphisms in autism.

TPH2 TPH1

7.54e-06296216958027
Pubmed

The role of the TPH1 and TPH2 genes for nicotine dependence: a genetic association study in two different age cohorts.

TPH2 TPH1

7.54e-06296217986837
Pubmed

Hyaluronan Synthases' Expression and Activity Are Induced by Fluid Shear Stress in Bone Marrow-Derived Mesenchymal Stem Cells.

HAS1 HAS2

7.54e-06296233803805
Pubmed

Dynamic changes in cervical glycosaminoglycan composition during normal pregnancy and preterm birth.

HAS1 HAS2

7.54e-06296222529214
Pubmed

Synthesis of serotonin by a second tryptophan hydroxylase isoform.

TPH2 TPH1

7.54e-06296212511643
Pubmed

WNT7A/B promote choroidal neovascularization.

WNT7A WNT7B

7.54e-06296229864439
Pubmed

Decreased expression of hyaluronan synthase 1 and 2 associates with poor prognosis in cutaneous melanoma.

HAS1 HAS2

7.54e-06296227184066
Pubmed

Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.

TPH2 TPH1

7.54e-06296218923670
Pubmed

Genetic, Psychological, and Personal Network Factors Associated With Changes in Binge Drinking Over 2 Years Among Mexican Heritage Adolescents in the USA.

TPH2 TPH1

7.54e-06296229697747
Pubmed

Expression, purification and enzymatic characterization of the catalytic domains of human tryptophan hydroxylase isoforms.

TPH2 TPH1

7.54e-06296219816759
Pubmed

Isoform-Specific Substrate Inhibition Mechanism of Human Tryptophan Hydroxylase.

TPH2 TPH1

7.54e-06296229035515
Pubmed

Deficiency of hyaluronan synthase 1 (Has1) results in chronic joint inflammation and widespread intra-articular fibrosis in a murine model of knee joint cartilage damage.

HAS1 HAS2

7.54e-06296226521733
Pubmed

Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11.

HOXA11 HOXD11

7.54e-0629627596412
Pubmed

The tryptophan hydroxylase gene influences risk for bipolar disorder but not major depressive disorder: results of meta-analyses.

TPH2 TPH1

7.54e-06296219032713
Pubmed

Common genetic variations in TPH1/TPH2 genes are not associated with schizophrenia in Japanese population.

TPH2 TPH1

7.54e-06296220144688
Pubmed

A unique central tryptophan hydroxylase isoform.

TPH2 TPH1

7.54e-06296214563478
Pubmed

Human placenta expresses both peripheral and neuronal isoform of tryptophan hydroxylase.

TPH2 TPH1

7.54e-06296228751217
Pubmed

Hyaluronan deficiency in tumor stroma impairs macrophage trafficking and tumor neovascularization.

HAS1 HAS2

7.54e-06296220823158
Pubmed

Cutting Edge: IL-1R1 Mediates Host Resistance to Mycobacterium tuberculosis by Trans-Protection of Infected Cells.

PTPRC IL1R1

7.54e-06296230068597
Pubmed

The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1+ hematoendothelial progenitors.

PTPRC HAS1 HAS2

1.11e-051696333454424
Pubmed

Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm control.

HAS2 MCF2L NR2F2

1.35e-051796333706013
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

THOC1 RANBP2 PBRM1 CCNB2 TRRAP SNRNP200

1.75e-0519596619454010
Pubmed

Expression of hyaluronan synthase genes in umbilical cord blood stem/progenitor cells.

HAS1 HAS2

2.26e-05396216564133
Pubmed

Analysis of human hyaluronan synthase gene transcriptional regulation and downstream hyaluronan cell surface receptor mobility in myofibroblast differentiation.

HAS1 HAS2

2.26e-05396225325984
Pubmed

Mammalian hyaluronan synthases: investigation of functional relationships in vivo.

HAS1 HAS2

2.26e-05396210093717
Pubmed

Cyclooxygenase inhibitors repress vascular hyaluronan-synthesis in murine atherosclerosis and neointimal thickening.

HAS1 HAS2

2.26e-05396219320776
Pubmed

Transient expression of secretin in serotoninergic neurons of mouse brain during development.

TPH2 TPH1

2.26e-05396215610158
Pubmed

An in situ hybridization study of Hyaluronan synthase (Has) mRNA in developing mouse molar and incisor tooth germs.

HAS1 HAS2

2.26e-05396227289075
Pubmed

Functional specificity of the Hoxa13 homeobox.

HOXA11 HOXD11

2.26e-05396211688568
Pubmed

Hyaluronan Regulates Eyelid and Meibomian Gland Morphogenesis.

HAS1 HAS2

2.26e-05396230046813
Pubmed

TNF-alpha, IFN-gamma, and IL-1beta modulate hyaluronan synthase expression in human skin fibroblasts: synergistic effect by concomital treatment with FeSO4 plus ascorbate.

HAS1 HAS2

2.26e-05396216786194
Pubmed

Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3.

HAS1 HAS2

2.26e-05396225795779
Pubmed

Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.

HAS1 HAS2

2.26e-05396223303191
Pubmed

Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive symptoms.

TPH2 TPH1

2.26e-05396222483952
Pubmed

Hyaluronan expressed by the hematopoietic microenvironment is required for bone marrow hematopoiesis.

HAS1 HAS2

2.26e-05396222654110
Pubmed

Manipulation of hyaluronan synthase expression in prostate adenocarcinoma cells alters pericellular matrix retention and adhesion to bone marrow endothelial cells.

HAS1 HAS2

2.26e-05396211790779
Pubmed

Association of hyaluronic acid family members (HAS1, HAS2, and HYAL-1) with bladder cancer diagnosis and prognosis.

HAS1 HAS2

2.26e-05396220960509
Pubmed

Hyaluronan synthase 3 overexpression promotes the growth of TSU prostate cancer cells.

HAS1 HAS2

2.26e-05396211431361
Pubmed

Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.

TPH2 TPH1

2.26e-05396227595322
Pubmed

GPR124 functions as a WNT7-specific coactivator of canonical β-catenin signaling.

WNT7A WNT7B

2.26e-05396225558062
Pubmed

Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice.

TPH2 TPH1

2.26e-05396217675372
Pubmed

Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties.

HAS1 HAS2

2.26e-05396210455188
Pubmed

Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family.

HAS1 HAS2

2.26e-0539629442026
Pubmed

Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space.

HAS1 HAS2

2.26e-05396224790187
Pubmed

Association between tryptophan hydroxylase 2 polymorphism and anger-related personality traits among young Korean women.

TPH2 TPH1

2.26e-05396220628266
Pubmed

Perturbation of hyaluronan synthesis in the trabecular meshwork and the effects on outflow facility.

HAS1 HAS2

2.26e-05396222695958
Pubmed

Three vertebrate hyaluronan synthases are expressed during mouse development in distinct spatial and temporal patterns.

HAS1 HAS2

2.26e-05396215765504
Pubmed

Genetic moderation of cocaine subjective effects by variation in the TPH1, TPH2, and SLC6A4 serotonin genes.

TPH2 TPH1

2.26e-05396228590957
Pubmed

Hyaluronan Modulates the Biomechanical Properties of the Cornea.

HAS1 HAS2

2.26e-05396236478198
Pubmed

Crucial role of estrogen for the mammalian female in regulating semen coagulation and liquefaction in vivo.

WNT7A KLKB1

2.26e-05396228414719
Pubmed

Hyaluronan Derived From the Limbus is a Key Regulator of Corneal Lymphangiogenesis.

HAS1 HAS2

2.26e-05396230897620
Pubmed

A link between serotonin-related gene polymorphisms, amygdala activity, and placebo-induced relief from social anxiety.

TPH2 TPH1

2.26e-05396219052197
Pubmed

Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum.

HOXA11 HOXD11

2.26e-0539629250683
Pubmed

Analysis of hyaluronic acid in the endometrium of women with polycystic ovary syndrome.

HAS1 HAS2

2.26e-05396230614308
Pubmed

In vitro synthesis of hyaluronan by a single protein derived from mouse HAS1 gene and characterization of amino acid residues essential for the activity.

HAS1 HAS2

2.26e-05396210617644
Pubmed

Involvement of hyaluronan in regulation of fibroblast phenotype.

HAS1 HAS2

2.26e-05396217611197
Pubmed

Hyaluronan synthases.

HAS1 HAS2

2.26e-0539629206724
Pubmed

Association between Serotonin-Related Polymorphisms in 5HT2A, TPH1, TPH2 Genes and Bipolar Disorder in Korean Population.

TPH2 TPH1

2.26e-05396220396435
Pubmed

Expression regulation of hyaluronan synthase in corneal endothelial cells.

HAS1 HAS2

2.26e-05396211006212
Pubmed

Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes.

HAS1 HAS2

2.26e-05396224057227
Pubmed

Phenylalanine hydroxylase contributes to serotonin synthesis in mice.

TPH2 TPH1

2.26e-05396233993565
Pubmed

Serotonin in pre-implantation mouse embryos is localized to the mitochondria and can modulate mitochondrial potential.

TPH2 TPH1

2.26e-05396218304982
Pubmed

Autoantibodies against aromatic amino acid hydroxylases in patients with autoimmune polyendocrine syndrome type 1 target multiple antigenic determinants and reveal regulatory regions crucial for enzymatic activity.

TPH2 TPH1

2.26e-05396223182718
Pubmed

Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons.

TPH2 TPH1

2.26e-05396221677183
Pubmed

Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.

DACT1 WNT7A WNT7B

2.61e-052196317943183
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PHKB ABCC1 RANBP2 PTPN7 MTMR6 GORASP2 PTPRC CCNB2 RICTOR CRYBG3 SGO1 CPVL

3.24e-051049961227880917
Pubmed

Hyaluronan in cervical epithelia protects against infection-mediated preterm birth.

HAS1 HAS2

4.51e-05496225384213
Pubmed

Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney.

HOXA11 HOXD11

4.51e-05496212060755
Pubmed

Clinical and genetic risk factors for suicide under the influence of alcohol in a Polish sample.

TPH2 TPH1

4.51e-05496219734157
Pubmed

T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions.

PTPRC RICTOR

4.51e-05496227903651
Pubmed

Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders.

TPH2 TPH1

4.51e-05496220043001
Pubmed

A molecular mechanism for Wnt ligand-specific signaling.

WNT7A WNT7B

4.51e-05496230026314
Pubmed

Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation.

HAS1 HAS2

4.51e-05496228863216
Pubmed

Transgenic expression of the human growth hormone minigene promotes pancreatic β-cell proliferation.

TPH2 TPH1

4.51e-05496226202070
Pubmed

Genes within the serotonergic system are differentially expressed in human brain.

TPH2 TPH1

4.51e-05496219445671
Pubmed

Dynamic states of cervical epithelia during pregnancy and epithelial barrier disruption.

HAS1 HAS2

4.51e-05496236718364
Pubmed

Inverse expression of hyaluronidase 2 and hyaluronan synthases 1-3 is associated with reduced hyaluronan content in malignant cutaneous melanoma.

HAS1 HAS2

4.51e-05496223560496
Pubmed

Putative hyaluronan synthase mRNA are expressed in mouse skin and TGF-beta upregulates their expression in cultured human skin cells.

HAS1 HAS2

4.51e-0549629457904
Pubmed

An association study of suicide and candidate genes in the serotonergic system.

TPH2 TPH1

4.51e-05496223313272
Pubmed

The control and importance of hyaluronan synthase expression in palatogenesis.

HAS1 HAS2

4.51e-05496223382716
Pubmed

Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.

PTPRC CSF2RB

4.51e-05496224821911
InteractionRGPD3 interactions

RANBP2 RGPD8 RICTOR CEP152 RGPD5

2.75e-0647955int:RGPD3
InteractionRGPD4 interactions

RANBP2 RGPD8 RICTOR RGPD5

3.18e-0622954int:RGPD4
InteractionRGPD1 interactions

RANBP2 PBRM1 RGPD8 RICTOR RGPD5

3.39e-0649955int:RGPD1
InteractionRGPD2 interactions

RANBP2 RGPD8 RICTOR RGPD5

7.48e-0627954int:RGPD2
InteractionTPH1 interactions

GORASP2 TPH2 TPH1

2.80e-0513953int:TPH1
GeneFamilyGlycosyltransferase family 2

HAS1 HAS2

1.78e-046632428
GeneFamilyKallikreins

KLK8 KLKB1

1.39e-0316632616
GeneFamilyWnt family|Endogenous ligands

WNT7A WNT7B

1.97e-0319632360
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

KRT72 ABCC1 RANBP2 DENND4A PTPRC RICTOR

1.13e-061569661545169694f686d28648a68b552c2ae606599d66
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL24A1 ANKRD30B ZFHX3 CRYBG3 MDGA1 CDH9

1.80e-06169966716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DACT1 SGIP1 CCNB2 DYNLT5 ZFHX3 SGO1

2.20e-061759663e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL24A1 NETO1 TRPC5 ANKRD30B CPVL CDH9

2.51e-061799661ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CRISPLD2 CFAP54 NETO1 ZAR1 IL1R1 NR2F2

2.51e-06179966e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 COL24A1 SGIP1 C1S MDGA1 EPB42

2.68e-06181966b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 SGIP1 DYNLT5 ZFHX3 MDGA1 NR2F2

2.95e-06184966327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 SGIP1 C1S HAS2 IL1R1 HYDIN

3.13e-06186966f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCell(5)_Fibroblast-J_(Lipofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CRISPLD2 KLK8 C1S HAS1 HAS2 IL1R1

4.24e-06196966afa29399decd17fda7d63add5039ff778627ccc2
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

CRISPLD2 ABCC1 COL24A1 SPATA6 ZFHX3 HAS2

4.24e-06196966e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CRISPLD2 DACT1 ETNK2 C1S HAS2 ZNF287

4.36e-0619796631c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 COL24A1 C1S CRYBG3 HAS2 IL1R1

4.49e-061989667582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IQGAP2 C1S CAPN5 CRYBG3 HAS2 IL1R1

4.62e-0619996656d72da6a5fab9cbb2975fe6f87a631debaba6a8
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Glia_progenitor_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ABCC1 PTPRC WNT7B HAS2 CPVL NR2F2

4.76e-062009664b937b1d0179d1d0e51931f35720e205d460a07e
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPRC IQGAP2 SGO1 CPVL ST18

2.16e-051559659f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellCOVID-19-Myeloid-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

PTPRC IQGAP2 TRGV5 CPVL ST18

2.23e-05156965a07a9096799e4ba663841c70035b4b32c1fda4f9
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 SPATA6 CEP152 KIF24 HYDIN

2.30e-05157965410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellHealthy/Control-RBC|Healthy/Control / Disease group and Cell class

RGPD8 C1S MCF2L EPB42 TPH1

2.37e-051589651fec4f9affdbfba2e281183b717d4d357d474400
ToppCellControl-B_naive-12|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NETO1 FKTN OAS2 CRYBG3 CPVL

2.37e-0515896541318f864770370ce77ed3fa4a84f76c0c22c482
ToppCellHealthy/Control-RBC|World / Disease group and Cell class

RGPD8 C1S MCF2L EPB42 TPH1

2.52e-05160965f10871238e7bdf3e1f65a17070000477196e50fe
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NWD2 PKD2L1 ST18 KLKB1 HYDIN

2.67e-05162965bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FKTN C1S HAS1 CDH9 HYDIN

2.67e-0516296556f1789e69a6cb29956e46aba92b290847327c1f
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTPN7 IQGAP2 CCNB2 SLC34A3 SGO1

2.91e-0516596526c750f10f6401752e2e63d91dc844c81b29d735
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC ETNK2 OAS2 CPVL ST18

3.36e-05170965c638dfde9ce30190abbe0caea1c3eb874af09857
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FOCAD UNC119B IL1R1 MKS1 AFG1L

3.76e-0517496558300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SGIP1 CCNB2 DYNLT5 ATP9A SGO1

4.07e-05177965844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB IQGAP2 CCNB2 DYNLT5 LTBR

4.19e-05178965be8af4d85b8835a85a168639c37857dcaa6b00bf
ToppCellMid-temporal_gyrus_(MTG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL24A1 NWD2 ANKRD30B PKD2L1 CDH9

4.19e-05178965ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CRISPLD2 SGIP1 HOXD11 ZFHX3 NR2F2

4.30e-05179965111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL24A1 NWD2 TRPC5 ANKRD30B CDH9

4.30e-05179965065a50952e8703fa07767beb6b73a090bf378ca6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 HOXA11 DACT1 C1S NR2F2

4.41e-05180965ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 COL24A1 C1S HAS2 IL1R1

4.41e-05180965f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS2 HAS1 HAS2 IL1R1 CDH9

4.41e-051809656c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 SGIP1 WNT7B CPVL HYDIN

4.53e-051819656a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

COL24A1 SGIP1 CCNB2 DYNLT5 SGO1

4.53e-05181965be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FSIP2 PKD2L1 C10orf90 SLC34A3

4.71e-05929640754a79efc4c0659d9a2acfe4185bcae1a3e7206
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FSIP2 PKD2L1 C10orf90 SLC34A3

4.71e-0592964aee1fd2419dc1fc7039c0ac56f0ba23ed11d668f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL24A1 NWD2 NETO1 WNT7A TRPC5

4.90e-05184965ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CRISPLD2 SGIP1 HOXD11 IL1R1 NR2F2

5.29e-0518796576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DACT1 COL24A1 GLRB C1S HAS2

5.29e-05187965ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCellNeuronal_cells-Schwann_cells|World / Lineage and Cell class

GLRB C10orf90 SLC34A3 ATP9A ST18

5.56e-05189965371cdc92549269e45c23c5a5b3cae9c5d35ee217
ToppCellNeuronal_cells|World / Lineage and Cell class

GLRB C10orf90 SLC34A3 ATP9A ST18

5.56e-051899653948775a0ebd4b32c1623d5487f5581e6e2934d7
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

CRISPLD2 RANBP2 HAS1 HAS2 IL1R1

5.56e-0518996546e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 DACT1 C1S HAS1 HAS2

5.56e-051899656e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCellRA-14._Fibroblast_III|World / Chamber and Cluster_Paper

CRISPLD2 RANBP2 HAS1 HAS2 IL1R1

5.56e-05189965b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DACT1 SGIP1 C1S ZFHX3 NR2F2

5.70e-0519096510b02c62e72bfea9767e3e751011436925da823e
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 C1S HAS1 HAS2 IL1R1

5.85e-05191965f5ce33af56178333730be308253943c54a0724cf
ToppCellP07-Mesenchymal-developing_mesenchymal_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DACT1 SGIP1 CCNB2 SGO1 NR2F2

5.85e-05191965ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CRISPLD2 SGIP1 RGPD8 IL1R1 MDGA1

5.99e-051929650b954a4e5857dac45d97c491af9b27cb2d1bd339
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN7 IQGAP2 KLK8 IL1R1 MDGA1

5.99e-0519296503dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

CRISPLD2 COL24A1 SPATA6 C1S ZFHX3

5.99e-05192965356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 C1S HAS1 HAS2 IL1R1

5.99e-05192965a8b7c539dc3037071bf068f372e4215563e11de4
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOCAD DACT1 SGIP1 C1S NR2F2

5.99e-05192965158cc5736f154da1cb3186ffbf186eae10483e48
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 C1S HAS1 HAS2 IL1R1

5.99e-051929652143e1fad2e88b90d668e12af37b2092d379090f
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 C1S HAS1 HAS2 IL1R1

5.99e-05192965904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOCAD DACT1 SGIP1 C1S NR2F2

5.99e-05192965f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

CRISPLD2 COL24A1 SGIP1 C1S IL1R1

6.14e-05193965e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

CRISPLD2 SGIP1 C1S IL1R1 NR2F2

6.14e-05193965ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellT_cells-CD56_bright_CD16-_NK_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

COL24A1 SGIP1 ZFHX3 MCF2L IL1R1

6.14e-05193965826457e2aafdb61ead8a0a44d8cf9088d310684b
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

CRISPLD2 SGIP1 ZFHX3 HAS1 IL1R1

6.14e-051939657426c291bac59e539c427bcaae18abc7d397d44e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 ETNK2 C1S ZFHX3 NR2F2

6.30e-05194965bf34737ae2dc218f890fbb9201c308b324415749
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL24A1 SPATA6 HAS2 IL1R1 NR2F2

6.30e-05194965b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

CRISPLD2 SGIP1 SPATA6 C1S ZFHX3

6.30e-05194965014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 ETNK2 C1S ZFHX3 NR2F2

6.30e-051949653bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 DACT1 GLRB C1S NR2F2

6.30e-05194965ca1f24070424b44b7a442e4fca761ebfbe24b063
ToppCellIPF-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

CSF2RB C1S HAS2 IL1R1 NR2F2

6.30e-05194965e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACT1 C1S HAS1 HAS2 CDH15

6.30e-05194965588c45dafa00547b2506e298a2434b1b5e15560d
ToppCellLA-14._Fibroblast_III|World / Chamber and Cluster_Paper

CRISPLD2 SGIP1 ZFHX3 HAS1 IL1R1

6.30e-05194965803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC119B PKD2L1 ST18 HYDIN TPH1

6.30e-051949652dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 ETNK2 C1S ZFHX3 NR2F2

6.30e-051949654ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 ETNK2 C1S ZFHX3 NR2F2

6.30e-05194965fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 KLK8 C1S HAS2 IL1R1

6.45e-051959650866aaf053762d1a021fcbccff058526078a99da
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL24A1 SGIP1 HAS2 IL1R1 NR2F2

6.45e-051959650e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

CRISPLD2 COL24A1 SPATA6 C1S ZFHX3

6.45e-051959656a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CRISPLD2 SGIP1 HOXD11 IL1R1 NR2F2

6.45e-051959653d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

AP1B1 ZFHX3 LTBR CPVL GDI2

6.61e-0519696528e9e191361966df3a9bd48450090577aa72a999
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 SGIP1 C1S CRYBG3 IL1R1

6.61e-051969652ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 KLK8 C1S HAS1 HAS2

6.61e-0519696546d665de09f8164690b9a3e0acf0b0afa3f81b3d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RANBP2 PTPRC AP1B1 OAS2 LTBR

6.61e-05196965e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 HOXA11 HOXD11 C1S IL1R1

6.77e-05197965ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCelldistal-mesenchymal-Lipofibroblast-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRISPLD2 KLK8 C1S HAS1 HAS2

6.77e-05197965865010edcd7e3f79f505fcef7b33882095994aa8
ToppCelldistal-mesenchymal-Lipofibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRISPLD2 KLK8 C1S HAS1 HAS2

6.77e-05197965ceb83bdef16b58ee16193413bfb006f7715728b2
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA11 HOXD11 NETO1 C1S HAS2

6.77e-05197965236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CRISPLD2 COL24A1 ETNK2 MDGA1 NR2F2

6.77e-051979656806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell343B-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PTPN7 CCNB2 SGO1 CPVL GDI2

6.77e-05197965b340d6f041231e5c69140895aaa1e8d28bafb998
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP54 CCNB2 DYNLT5 KIF24 HYDIN

6.77e-051979656e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCelldistal-mesenchymal-Mesothelial-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRISPLD2 KLK8 C1S HAS1 EPB42

6.93e-05198965431bf719ee5cce4c9e8b6b405819b67e98fad3ca
ToppCelldistal-mesenchymal-Mesothelial|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRISPLD2 KLK8 C1S HAS1 EPB42

6.93e-0519896552e3cb45472dd6db31ae533e9ea0c3b550f11496
ToppCellFibroblasts|World / lung cells shred on cell class, cell subclass, sample id

CRISPLD2 C1S CAPN5 HAS1 HAS2

7.10e-05199965e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCellASK452-Mesenchymal-Fibroblast|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CRISPLD2 SGIP1 C1S HAS2 IL1R1

7.10e-051999654d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCellILEUM-non-inflamed-(8)_Fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CRISPLD2 C1S CAPN5 CRYBG3 HAS2

7.10e-05199965d9d7f36b4b5592b7855448730044c90997b55499
ToppCellASK452-Mesenchymal|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CRISPLD2 SGIP1 C1S HAS2 IL1R1

7.10e-0519996593e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 C1S CRYBG3 HAS2 IL1R1

7.10e-051999656139687a3a5025cb98da4dba0183f95fcae3dc61
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KRT72 PTPN7 PTPRC IQGAP2 TRGV5

7.10e-05199965eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCell(5)_Fibroblast-F|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CRISPLD2 C1S CAPN5 HAS1 HAS2

7.10e-051999651f66db4f502de4a5159cde90fcb3befb26b8d375
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

CRISPLD2 SGIP1 HOXD11 IL1R1 NR2F2

7.10e-051999659503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CRISPLD2 DACT1 SGIP1 ZFHX3 NR2F2

7.27e-05200965b22cae282591d8dead9869c2adbb9632615f50f7
ToppCellBiopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

CRISPLD2 C1S HAS1 HAS2 IL1R1

7.27e-052009650aa316b71f195ecf17ee897e307f8928a755a637
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-ILC|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DACT1 PTPRC IQGAP2 DYNLT5 CDH9

7.27e-0520096549ad6e2337886367fbfa2a7c7366687b701ddf39
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CRISPLD2 DACT1 SGIP1 ZFHX3 NR2F2

7.27e-0520096577631c471cc5d453a749784f838cfa6408caf09b
Drugalpha-difluoromethyldopa

TPH2 TPH1

1.76e-052962CID000129677
DrugSC-48274

TPH2 TPH1

1.76e-052962CID000040914
Drugtetrahydroneopterin

TPH2 HPX TPH1

2.01e-0513963CID000161510
DrugDacarbazine [4342-03-4]; Up 200; 22uM; PC3; HT_HG-U133A

CRISPLD2 ZNF155 CHRNA9 GLRB ETNK2 HPX MCF2L

2.03e-051979674480_UP
Drugharmol

ABCC1 HAS1 HAS2 MCF2L

2.41e-0540964CID000068094
Drugalpha-methyltryptophan

TRPC5 TPH2 TPH1

3.19e-0515963CID000095438
Drug4-(beta-amidinoethenyl)phenyl-4-guanidinobenzoate

C1S KLKB1

5.26e-053962CID006439563
Drug2,4,5-trihydroxymethamphetamine

TPH2 TPH1

5.26e-053962CID000131985
Drug2,4,5-trihydroxyamphetamine

TPH2 TPH1

5.26e-053962CID000126234
Drug4-methyl-alpha-ethyl-m-tyramine

TPH2 TPH1

5.26e-053962CID000168028
DrugAC1Q5QKX

TPH2 TPH1

5.26e-053962CID000164302
Drugepisol

C1S KLKB1

5.26e-053962CID000017456
DrugFmtrp

TPH2 TPH1

5.26e-053962CID000126435
Drug2-hydroxy-4,5-methylenedioxyamphetamine

TPH2 TPH1

5.26e-053962CID000126859
DiseaseOccipital Encephalocele

DACT1 MKS1

9.41e-062912C0014067
Diseaselung small cell carcinoma (is_implicated_in)

PBRM1 CHRNA9 RICTOR

8.79e-0528913DOID:5409 (is_implicated_in)
DiseasePsychotic Disorders

PBRM1 PTPRC CSF2RB TPH2

2.75e-04101914C0033975
Diseasered blood cell density measurement

FOCAD UNC119B DENND4A PBRM1 PTPRC CHRNA9 HOXD11 WNT7A WNT7B RICTOR

3.84e-048809110EFO_0007978
DiseaseLimb Deformities, Congenital

HOXA11 HOXD11

1.24e-0317912C0206762
DiseaseFemale Urogenital Diseases

HOXA11 WNT7A

1.39e-0318912C1720887
DiseaseAlcoholic Intoxication, Chronic

SGIP1 ST18 CDH9 CDH15 TPH1

1.47e-03268915C0001973
Diseaselung cancer (is_implicated_in)

SETDB1 RTEL1 RICTOR

1.57e-0374913DOID:1324 (is_implicated_in)
Diseasecarnitine measurement

UNC119B ABCC1 PKD2L1

1.70e-0376913EFO_0010469
Diseasehaptoglobin measurement

ZFHX3 HYDIN

1.90e-0321912EFO_0004640
Diseasehemoglobin measurement, mean corpuscular hemoglobin

DENND4A PTPRC

2.09e-0322912EFO_0004509, EFO_0004527
Diseasepartial thromboplastin time

C1S KLKB1

2.48e-0324912EFO_0004310
Diseaseankylosing spondylitis

CSF2RB LTBR IL1R1

2.83e-0391913EFO_0003898

Protein segments in the cluster

PeptideGeneStartEntry
DKVYLPTNCYRLREA

ACCSL

446

Q4AC99
DRCEDITQNYKYPEG

EPB42

426

P16452
TQQPCARYEAEYGEK

CFAP54

1806

Q96N23
KCQRYQTPYLSEETT

CEP152

1631

O94986
QNYTCLPDATYQKDI

ANKRD30B

451

Q9BXX2
TYKQEVYCNIPDATS

CRYBG3

2306

Q68DQ2
VEDSLCVPQYNKYRE

AACS

566

Q86V21
QDDYPNKIFLAYRVC

GOT1L1

26

Q8NHS2
SYLQVEEYEPELCRQ

DYNLT5

91

Q8N7M0
YCNTVQLDSGIDYRK

AFG1L

271

Q8WV93
PQEAESYCAQYKVLT

CHRNA9

411

Q9UGM1
YPNKYESVIATLCEN

AP1B1

421

Q10567
KPYEDQNYSALRRDC

CAPN5

6

O15484
ARPQYYKLIEECISQ

DIAPH1

426

O60610
ENVYPKLREFCRENY

NWD2

61

Q9ULI1
VSYKAGLICRYPQED

DENND4A

206

Q7Z401
KKYICTYINVQERDP

RANBP2

46

P49792
PRQCIELYFDEKYSI

NETO1

76

Q8TDF5
KKYICTYINVQERDP

RGPD5

46

Q99666
KKYICTYINVQERDP

RGPD8

46

O14715
SQCALEEYVRSQYPN

NR2F2

341

P24468
TTKEAYCYENPEILA

SLC34A3

581

Q8N130
KECPEYTVRQLTIQY

PTPN7

226

P35236
LKNLRPQDYASYTCQ

MDGA1

201

Q8NFP4
CTYNEPESLIYKDAL

PBRM1

736

Q86U86
DYLDQPCYETINRIK

GDI2

196

P50395
LKLYVYNTDTDNCRE

GORASP2

161

Q9H8Y8
YDQVRYICETQGLPK

HIPK4

221

Q8NE63
LSDANRDYKICETYP

MTMR6

146

Q9Y217
TDPYCRLLENQYKSL

FSIP2

86

Q5CZC0
NFLRCTEPEDQLYYV

CPVL

316

Q9H3G5
VNEVDYCLYPARETQ

ETNK2

291

Q9NVF9
NNLCYREETYTPKPE

CRISPLD2

231

Q9H0B8
AEKPYCSQVDFIYRQ

KIF24

936

Q5T7B8
ELSNYDCYGKPIEVN

GLRB

431

P48167
CPDYQSYFRTIEELQ

KRT35

141

Q92764
KQYEDSCRVYQASSP

ATP9A

486

O75110
CPYTKYQIRELEREF

HOXA11

246

P31270
QEYLKPYEECQTLID

OAS2

21

P29728
EKYPQTFDDICLYSE

RICTOR

1641

Q6R327
IEYVKQNPLYDTERC

METTL6

116

Q8TCB7
ETIPLQTLRCYNDYT

CSF2RB

26

P32927
NPLEAKLYQQTIYCD

HYDIN

426

Q4G0P3
CDLVSKNGNDVYRYP

DACT1

256

Q9NYF0
ENPQLCSDYVKDIYQ

CCNB2

126

O95067
AYQEDPDYLRKCLQS

HAS2

91

Q92819
CPYTKYQIRELEREF

HOXD11

271

P31277
EKVAYDCSPNKNRYL

REXO1L1P

326

Q8IX06
YPENSRCEYQIRLEK

C1S

196

P09871
YRQCNIIPYSKDVDL

FKTN

306

O75072
ISAYQEDPAYLRQCL

HAS1

101

Q92839
FQIYEKYCQNKPRSE

MCF2L

721

O15068
SDKPGVYTNICRYLD

KLK8

236

O60259
PLVTNEECQKRYQDY

KLKB1

541

P03952
TAYDPDARNNLIKYS

CDH9

406

Q9ULB4
QLQRLSYSKDYDPED

CDH15

406

P55291
EDYYSVENPANKRRS

IL1R1

276

P14778
LYCEPSQLQEYAKLR

FOCAD

181

Q5VW36
SLEDPNRCYYKPAEI

PHKB

341

Q93100
QLEEPYYRSVIQACA

ABCC1

731

P33527
PNLYCYSDVEKLNAA

HPX

431

P02790
VCPYYLSRNLKQQAD

RTEL1

206

Q9NZ71
SNANDIIPECADKYY

IQGAP2

566

Q13576
RKVPKYQDDAYSQCA

PRDM11

366

Q9NQV5
TSEYNSKYLRDPLDQ

PPP1R32

176

Q7Z5V6
DDSDDLYLPTCKYIQ

SGO1

376

Q5FBB7
APQRLLYYDVSNSKD

TRGV5

61

A0A0B4J1U4
RVEEISPNIRYCAYN

SRP68

236

Q9UHB9
QYKRLEECLPTGVYE

SETDB1

766

Q15047
NSSRKEDRYSCYQEL

ST18

111

O60284
VSQQCPDSIYYVDKS

C10orf90

256

Q96M02
PSAEASADYCRYVKQ

COL24A1

226

Q17RW2
SKYCGYREDNIPQLE

TPH1

201

P17752
TDLVYIEKSPNYCEE

WNT7B

266

P56706
EYQEYGEKPDTRNQC

ZNF136

131

P52737
PTEECLSKYDIYRNN

ZNF287

306

Q9HBT7
DLYQNETACQSPLDY

MKS1

91

Q9NXB0
ETACQSPLDYQYRQE

MKS1

96

Q9NXB0
CEPSSTDLRIDYKYN

SGIP1

696

Q9BQI5
PEKLTAENRYYCESC

USP35

771

Q9P2H5
ENYLCKPEDNIYSID

UNC119B

81

A6NIH7
TSCQYDLRSQVIYPE

SLFN12

506

Q8IYM2
LSCYDVYSPDKEEQL

PKD2L1

221

Q9P0L9
LTKYCGYREDNVPQL

TPH2

246

Q8IWU9
QTCRDQEKEYYEPQH

LTBR

41

P36941
CNRYPNIELSYEVVD

SNRNP200

2011

O75643
TDLVYIEKSPNYCEE

WNT7A

266

O00755
TNYENRIYSLKVECG

UBE2V2

56

Q15819
PQQLYSEEKSYTCDE

ZNF155

166

Q12901
YYETRAIDEPNNCKG

TRPC5

541

Q9UL62
PTCDEKYANITVDYL

PTPRC

226

P08575
ALDCLKSANTEPYYR

TRRAP

946

Q9Y4A5
DCYNQRIYSSLPVEV

SNRNP48

131

Q6IEG0
RSKYCINAKNYEQPT

SPATA6

196

Q9NWH7
LQDYFRNPVQCYEKI

THOC1

241

Q96FV9
TCQKSYNPYRVEDIT

ZAR1

361

Q86SH2
PYCKYSNADVNRLRV

ZFHX3

1226

Q15911
NNCRKNLEPIYEGYI

KRT72

166

Q14CN4