Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

4.89e-07181845GO:0008569
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 ATP6V1A SMARCA5 ABCA2 DNAH10 ABCA12 SMC4 HELQ DNAH7 KIF24 ZRANB3 ABCB4 BPTF DNAH12 ATAD1 MOV10L1 ATP2C2 NAV2 HELZ DNAH9

1.06e-0661418420GO:0140657
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

5.21e-06281845GO:0051959
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP6V1A SMARCA5 ABCA2 DNAH10 ABCA12 SMC4 HELQ DNAH7 ABCB4 DNAH12 ATAD1 MOV10L1 ATP2C2 NAV2 DNAH9

1.52e-0544118415GO:0016887
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

2.16e-05371845GO:0045505
GeneOntologyMolecularFunctionmicrotubule motor activity

DNHD1 DNAH10 DNAH7 KIF24 DNAH12 DNAH9

4.54e-05701846GO:0003777
GeneOntologyMolecularFunctionprotein-cysteine methyltransferase activity

KMT2A DNMT3A

8.45e-0521842GO:0106363
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNHD1 DNAH10 DNAH7 KIF24 DNAH12 DNAH9 MYO16

1.12e-041181847GO:0003774
GeneOntologyMolecularFunctionceramide floppase activity

ABCA2 ABCB4

2.52e-0431842GO:0099038
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ATP6V1A SMARCA5 ABCA2 DNAH10 ABCA12 LRRK2 SMC4 RGS9 HELQ DNAH7 ABCB4 DNAH12 RGS6 ATAD1 MOV10L1 ATP2C2 NAV2 DNAH9

3.05e-0477518418GO:0017111
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCA2 ABCB4

5.01e-0441842GO:0046623
GeneOntologyMolecularFunctionpyrophosphatase activity

ATP6V1A SMARCA5 ABCA2 DNAH10 ABCA12 LRRK2 SMC4 RGS9 HELQ DNAH7 ABCB4 DNAH12 RGS6 ATAD1 MOV10L1 ATP2C2 NAV2 DNAH9

7.74e-0483918418GO:0016462
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

PITPNM2 ABCB4 PITPNM1

7.82e-04201843GO:0008525
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ATP6V1A SMARCA5 ABCA2 DNAH10 ABCA12 LRRK2 SMC4 RGS9 HELQ DNAH7 ABCB4 DNAH12 RGS6 ATAD1 MOV10L1 ATP2C2 NAV2 DNAH9

7.84e-0484018418GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ATP6V1A SMARCA5 ABCA2 DNAH10 ABCA12 LRRK2 SMC4 RGS9 HELQ DNAH7 ABCB4 DNAH12 RGS6 ATAD1 MOV10L1 ATP2C2 NAV2 DNAH9

7.84e-0484018418GO:0016818
GeneOntologyMolecularFunctionhemoglobin alpha binding

HBG1 HBG2

8.29e-0451842GO:0031721
GeneOntologyMolecularFunctionquaternary ammonium group binding

PITPNM2 APOC1 CHRNB2 PITPNM1

8.42e-04461844GO:0050997
GeneOntologyMolecularFunctionpiRNA binding

PIWIL2 MOV10L1

1.24e-0361842GO:0034584
GeneOntologyCellularComponentinner dynein arm

DNHD1 DNAH10 DNAH7 DNAH12

1.22e-06101864GO:0036156
GeneOntologyCellularComponentaxonemal dynein complex

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

2.43e-06251865GO:0005858
GeneOntologyCellularComponentNoRC complex

SMARCA5 BAZ2A

7.87e-0521862GO:0090536
GeneOntologyCellularComponentdynein complex

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

1.17e-04541865GO:0030286
GeneOntologyCellularComponentISWI-type complex

SMARCA5 BPTF BAZ2A

2.35e-04141863GO:0031010
GeneOntologyCellularComponentglycerol-3-phosphate dehydrogenase (FAD) complex

GPD2 GPD1L

2.35e-0431862GO:0009331
GeneOntologyCellularComponentstriated muscle myosin thick filament

MYOM1 TRIM32

4.67e-0441862GO:0005863
GeneOntologyCellularComponentperinucleolar compartment

CELF1 SORL1

7.74e-0451862GO:0097356
DomainDynein_heavy_dom-2

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

1.73e-07141865IPR013602
DomainDHC_N2

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

1.73e-07141865PF08393
DomainDHC_fam

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

2.57e-07151865IPR026983
DomainDynein_heavy

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

2.57e-07151865PF03028
DomainDynein_heavy_dom

DNHD1 DNAH10 DNAH7 DNAH12 DNAH9

2.57e-07151865IPR004273
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH7 DNAH12 DNAH9

8.82e-06141864IPR024317
DomainDynein_HC_stalk

DNHD1 DNAH10 DNAH7 DNAH9

8.82e-06141864IPR024743
DomainMT

DNHD1 DNAH10 DNAH7 DNAH9

8.82e-06141864PF12777
DomainAAA_8

DNAH10 DNAH7 DNAH12 DNAH9

8.82e-06141864PF12780
DomainAAA

ABCA2 DNAH10 ABCA12 DNAH7 ABCB4 DNAH12 ATAD1 NAV2 DNAH9

1.42e-051441869SM00382
DomainAAA+_ATPase

ABCA2 DNAH10 ABCA12 DNAH7 ABCB4 DNAH12 ATAD1 NAV2 DNAH9

1.42e-051441869IPR003593
DomainP-loop_NTPase

DNHD1 ATP6V1A SMARCA5 ABCA2 DNAH10 ABCA12 LRRK2 SMC4 HELQ DNAH7 KIF24 ZRANB3 ABCB4 DNAH12 ATAD1 MOV10L1 NAV2 HELZ DNAH9 MYO16 CHST3

1.14e-0484818621IPR027417
Domain-

DNHD1 ATP6V1A SMARCA5 ABCA2 DNAH10 ABCA12 LRRK2 SMC4 HELQ DNAH7 ZRANB3 ABCB4 DNAH12 ATAD1 MOV10L1 NAV2 HELZ DNAH9 CHST3

1.71e-04746186193.40.50.300
DomainKelch

KLHL40 IPP KLHL41 KLHDC8A KLHL13

2.77e-04581865SM00612
DomainGal_Oxase/kelch_b-propeller

KLHL40 IPP KLHL41 KLHDC8A KLHL13

3.01e-04591865IPR011043
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH12 DNAH9

3.26e-04141863IPR011704
DomainAAA_5

DNAH10 DNAH12 DNAH9

3.26e-04141863PF07728
DomainDDT

BPTF BAZ2A

5.84e-0441862PF02791
DomainKelch_1

KLHL40 IPP KLHL41 KLHDC8A KLHL13

6.65e-04701865PF01344
DomainKelch_1

KLHL40 IPP KLHL41 KLHDC8A KLHL13

6.65e-04701865IPR006652
DomainBTB-kelch_protein

KLHL40 IPP KLHL41 KLHL13

8.68e-04431864IPR017096
Domain-

LRRK2 KRIT1 ASB18 KANK1 ANKRD20A4P MIB1 ANKRD30A MYO16 ANKRD20A1

8.74e-0424818691.25.40.20
DomainDDT

BPTF BAZ2A

9.67e-0451862SM00571
DomainIP_trans

PITPNM2 PITPNM1

9.67e-0451862PF02121
DomainDDT_dom

BPTF BAZ2A

9.67e-0451862IPR018501
DomainWHIM1_dom

BPTF BAZ2A

9.67e-0451862IPR028942
DomainWHIM2_dom

BPTF BAZ2A

9.67e-0451862IPR028941
DomainHaemoglobin_b

HBG1 HBG2

9.67e-0451862IPR002337
DomainWSD

BPTF BAZ2A

9.67e-0451862PF15613
DomainWHIM1

BPTF BAZ2A

9.67e-0451862PF15612
DomainAnkyrin_rpt-contain_dom

LRRK2 KRIT1 ASB18 KANK1 ANKRD20A4P MIB1 ANKRD30A MYO16 ANKRD20A1

1.03e-032541869IPR020683
DomainAnkyrin_rpt

LRRK2 KRIT1 ASB18 KANK1 ANKRD20A4P MIB1 ANKRD30A MYO16 ANKRD20A1

1.28e-032621869IPR002110
Domain-

KLHL40 IPP KLHL41 KLHDC8A

1.32e-034818642.120.10.80
DomainLNS2

PITPNM2 PITPNM1

1.44e-0361862IPR013209
DomainDDT

BPTF BAZ2A

1.44e-0361862PS50827
DomainPI_transfer

PITPNM2 PITPNM1

1.44e-0361862IPR001666
DomainLNS2

PITPNM2 PITPNM1

1.44e-0361862SM00775
DomainDDHD

PITPNM2 PITPNM1

1.44e-0361862PF02862
DomainDDHD

PITPNM2 PITPNM1

1.44e-0361862PS51043
DomainDDHD_dom

PITPNM2 PITPNM1

1.44e-0361862IPR004177
DomainLNS2

PITPNM2 PITPNM1

1.44e-0361862PF08235
DomainFAT

TRRAP PRKDC

1.44e-0361862PS51189
DomainFATC

TRRAP PRKDC

1.44e-0361862PS51190
DomainLNS2/PITP

PITPNM2 PITPNM1

1.44e-0361862IPR031315
DomainFAT

TRRAP PRKDC

1.44e-0361862PF02259
DomainPIK-rel_kinase_FAT

TRRAP PRKDC

1.44e-0361862IPR003151
DomainFATC_dom

TRRAP PRKDC

1.44e-0361862IPR003152
DomainPIK_FAT

TRRAP PRKDC

1.44e-0361862IPR014009
DomainDDHD

PITPNM2 PITPNM1

1.44e-0361862SM01127
DomainFATC

TRRAP PRKDC

1.44e-0361862SM01343
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

NELFE CUL2 ATP6V1A CACNA2D1 TBC1D15 ADRM1 U2SURP SMC4 CIR1 GEMIN5 TRRAP CDC42BPB PHGDH PSMD6 BPTF MYOF AP2B1 TRIM32 SMARCB1 CD63 PRKDC CTNNA2 HCCS

6.26e-0712971882333545068
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

GPD2 ATP6V1A CACNA2D1 TBC1D15 SMARCA5 SYNE1 U2SURP SMC4 IDH3A TRRAP F5 PRPF40A PHGDH NUP205 PSMD6 BPTF SUPT16H PRKDC SNRPD2 UTRN

8.24e-0710241882024711643
Pubmed

Exploration of 16 candidate genes identifies the association of IDE with Alzheimer's disease in Han Chinese.

APOC1 ACE CHRNB2 SORL1

1.43e-0616188420880607
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NELFE TBC1D15 SMARCA5 SMC4 GEMIN5 WWTR1 TRRAP CCNK PRPF40A PHGDH BPTF BAZ2A KMT2A PRKDC

1.98e-065491881438280479
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

GPD2 ATP6V1A ABCA2 SYNE1 SAXO1 ACE PHGDH PSMD6 MYOF AP2B1 MOV10L1 KMT2A PRKDC SNRPD2 UTRN IQGAP3 MYO16

2.11e-068071881730575818
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SMARCA5 U2SURP SMC4 GEMIN5 TRRAP PRPF40A NUP205 BPTF AP2B1 BAZ2A KMT2A DLAT HELZ PRKDC UTRN

3.04e-066531881522586326
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CUL2 TRPC4AP ADRM1 SMC4 ECT2 NUP205 MRPL39 PSMD6 ATAD1 AP2B1 TRIM32 PLCL2 DHPS SUPT16H HELZ IFT122 NKTR SNRPD2 HCCS IQGAP3 CHST3 SORL1

3.10e-0613211882227173435
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MYOM1 SYNE1 KLHL41 ECT2 CDC42BPB PHGDH NEO1 KLF10 TRIM32 GYG1 SUPT16H UTRN TGS1

3.54e-064971881323414517
Pubmed

CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis.

SMARCA5 WWTR1 NDN BAZ2A

4.61e-0621188422154806
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

GPD2 CUL2 SMARCA5 ADRM1 SMC4 GEMIN5 IDH3A PRPF40A PHGDH NUP205 MRPL39 PSMD6 MYOF FCGBP ATAD1 TRIM32 GYG1 SUPT16H CD63 PRKDC SNRPD2 UTRN

5.33e-0613671882232687490
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NELFE U2SURP SMC4 PTPN22 TRRAP PIAS1 CCNK PHGDH PSMD6 BPTF THYN1 CELF1 CELF2 AP2B1 SMARCB1 KMT2A PRKDC SNRPD2 MAP2K7

9.51e-0611031881934189442
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GPD2 PITPNM2 ATP6V1A CACNA2D1 SYNE1 GEMIN5 IDH3A CDC42BPB PRPF40A PHGDH PITPNM1 GPD1L PSMD6 GRK2 AP2B1 CRACDL KMT2A DLAT CTNNA2 SNRPD2 UTRN SLC25A23

1.09e-0514311882237142655
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

ATP6V1A TBC1D15 SMARCA5 SMC4 GEMIN5 IDH3A PHGDH NUP205 PSMD6 AP2B1 SUPT16H DLAT PRKDC MAP2K7

1.10e-056381881433239621
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

NELFE CUL2 ATP6V1A SMARCA5 ADRM1 SMC4 GEMIN5 TRRAP PIAS1 CCNK PRPF40A NUP205 BPTF SUPT16H SMARCB1 KMT2A PRKDC IRX2

1.11e-0510141881832416067
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

SMARCA5 U2SURP SMC4 TRRAP CELF1 AP2B1 SUPT16H SMARCB1 KMT2A PRKDC UTRN

1.11e-053941881127248496
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

SMC4 GEMIN5 CDC42BPB MYOF SUPT16H ANKRD30A PRKDC IQGAP3

1.54e-05202188833005030
Pubmed

The human plasma proteome: history, character, and diagnostic prospects.

IDH3A HBG1 HBG2

1.81e-0510188312488461
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

SMARCA5 ARID4A BPTF BAZ2A SUPT16H SMARCB1 DNMT3A

1.85e-05150188728242625
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

PTGES2 SMARCA5 U2SURP SMC4 IDH3A TRRAP PRKDC IQGAP3

2.10e-05211188817314511
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NELFE SMARCA5 GCFC2 ARID4A GEMIN5 TRRAP CCNK PRPF40A PITPNM1 BPTF MYOF BAZ2A KMT2A HELZ PRKDC

2.27e-057741881515302935
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GPRASP1 PTGES2 ABCA2 CYTH3 SYNE1 TTLL5 MCF2L2 CNRIP1 PIAS1 CDC42BPB KRIT1 ME3 FOCAD AP2B1 TRIM32 MIB1 DLAT IFT122 PRKDC UTRN

2.36e-0512851882035914814
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

GPD2 SMARCA5 SYNE1 U2SURP TRRAP CCNK PRPF40A PHGDH NUP205 BPTF THYN1 AP2B1 TRIM32 SUPT16H SMARCB1 PRKDC SNRPD2 DNMT3A

2.61e-0510821881838697112
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

SMARCA5 U2SURP TRRAP PIAS1 PRPF40A SUPT16H SMARCB1 PRKDC

2.83e-05220188835785414
Pubmed

Effect of the angiotensin-converting enzyme gene deletion polymorphism on the risk of venous thromboembolism.

ACE F5

2.91e-052188211122103
Pubmed

Two novel arrangements of the human fetal globin genes: G gamma-G gamma and A gamma-A gamma.

HBG1 HBG2

2.91e-05218826091051
Pubmed

An embryonic stage-specific enhancer within the murine β-globin locus mediates domain-wide histone hyperacetylation.

HBG1 HBG2

2.91e-052188221321362
Pubmed

A study on the genotype frequency of -158 Gγ (C→T) Xmn1 polymorphism in a sickle cell trait cohort from Siwa Oasis, Egypt.

HBG1 HBG2

2.91e-052188229932071
Pubmed

Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway.

HBG1 HBG2

2.91e-052188211172039
Pubmed

Sequences of G gamma, A gamma, and beta genes of the Greek (A gamma) HPFH mutant: evidence for a distal CCAAT box mutation in the A gamma gene.

HBG1 HBG2

2.91e-05218822413469
Pubmed

Evaluation of the roles of the Leiden V mutation and ACE I/D polymorphism in subtypes of ischaemic stroke.

ACE F5

2.91e-052188211596779
Pubmed

Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins.

HBG1 HBG2

2.91e-05218826323438
Pubmed

Human fetal hemoglobin F 1. Acetylation status.

HBG1 HBG2

2.91e-05218825554303
Pubmed

The transcription factor NFAT1 induces apoptosis through cooperation with Ras/Raf/MEK/ERK pathway and upregulation of TNF-α expression.

ZHX2 NFATC2

2.91e-052188223583303
Pubmed

Effect of HIV type 1 Tat protein on butyric acid-induced differentiation in a hematopoietic progenitor cell line.

HBG1 HBG2

2.91e-05218828911578
Pubmed

Ablation of TrkB expression in RGS9-2 cells leads to hyperphagic obesity.

NTRK2 RGS9

2.91e-052188224327964
Pubmed

The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription.

SMARCA5 BAZ2A

2.91e-052188212368916
Pubmed

Isolation and expression of Napor/CUG-BP2 in embryo development.

CELF1 CELF2

2.91e-052188212763013
Pubmed

Expression of a dominant negative CELF protein in vivo leads to altered muscle organization, fiber size, and subtype.

CELF1 CELF2

2.91e-052188221541285
Pubmed

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies.

LRRK2 NFATC2

2.91e-052188233055242
Pubmed

A novel C-T transition within the distal CCAAT motif of the G gamma-globin gene in the Japanese HPFH: implication of factor binding in elevated fetal globin expression.

HBG1 HBG2

2.91e-05218821698280
Pubmed

A history of the human fetal globin gene duplication.

HBG1 HBG2

2.91e-05218827332928
Pubmed

The frequency of factor V Leiden mutation, ACE gene polymorphism, serum ACE activity and response to ACE inhibitor and angiotensin II receptor antagonist drugs in Iranians type II diabetic patients with microalbuminuria.

ACE F5

2.91e-052188220853144
Pubmed

Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes.

HBG1 HBG2

2.91e-05218827438203
Pubmed

Amyloid-β-related genes SORL1 and ACE are genetically associated with risk for late-onset Alzheimer disease in the Chinese population.

ACE SORL1

2.91e-052188220625269
Pubmed

Intergenic transcripts regulate the epigenetic state of rRNA genes.

SMARCA5 BAZ2A

2.91e-052188216678107
Pubmed

Diversity and conservation of CELF1 and CELF2 RNA and protein expression patterns during embryonic development.

CELF1 CELF2

2.91e-052188223468433
Pubmed

A new (G)γ-globin variant causing low oxygen affinity: Hb F-Brugine/Feldkirch [(G)γ105(G7)Leu→His; HBG2: c.317T>A].

HBG1 HBG2

2.91e-052188224502349
Pubmed

The relationship between the variations in Gγ and Aγ promotors and the Hereditary Persistence of Fetal Hemoglobin (HPFH).

HBG1 HBG2

2.91e-052188229412791
Pubmed

Diverse epigenetic strategies interact to control epidermal differentiation.

SMARCA5 BPTF

2.91e-052188222729083
Pubmed

Oligomerization and ligand binding in a homotetrameric hemoglobin: two high-resolution crystal structures of hemoglobin Bart's (gamma(4)), a marker for alpha-thalassemia.

HBG1 HBG2

2.91e-052188211514664
Pubmed

Promoter region sequence differences in the A and G gamma globin genes of Brazilian sickle cell anemia patients.

HBG1 HBG2

2.91e-052188220602015
Pubmed

BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells.

BPTF PRKDC

2.91e-052188228579392
Pubmed

G gamma-196 C-->T, A gamma-201 C-->T: two novel mutations in the promoter region of the gamma-globin genes associated with nondeletional hereditary persistence of fetal hemoglobin in Greece.

HBG1 HBG2

2.91e-052188218096417
Pubmed

Hb F-Charlotte, an A gamma variant with a threonine residue in position gamma 75 and a glycine residue in position gamma 136.

HBG1 HBG2

2.91e-05218821714434
Pubmed

Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease.

LRRK2 IRX2

2.91e-052188232422864
Pubmed

Krit1/cerebral cavernous malformation 1 mRNA is preferentially expressed in neurons and epithelial cells in embryo and adult.

ACE KRIT1

2.91e-052188212204286
Pubmed

HbF-Lesvos: an HbF variant due to a novel G gamma mutation (:G gamma 75 ATA-->ACA) detected in a Greek family.

HBG1 HBG2

2.91e-05218828566966
Pubmed

The relationship of the factor V Leiden mutation or the deletion-deletion polymorphism of the angiotensin converting enzyme to postoperative thromboembolic events following total joint arthroplasty.

ACE F5

2.91e-052188211311153
Pubmed

Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation.

CELF2 MAP2K7

2.91e-052188226443849
Pubmed

The Greek A gamma beta+-HPFH observed in a large black family.

HBG1 HBG2

2.91e-05218822441598
Pubmed

A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most Animals.

PIWIL2 PNLDC1

2.91e-052188230193099
Pubmed

High levels of human gamma-globin gene expression in adult mice carrying a transgene of deletion-type hereditary persistence of fetal hemoglobin.

HBG1 HBG2

2.91e-05218829121456
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

ATP6V1A SMARCA5 U2SURP SMC4 GEMIN5 IDH3A PRPF40A NUP205 MRPL39 CELF1 CELF2 BAZ2A SUPT16H MIB1 SMARCB1 KMT2A HELZ NKTR PRKDC SNRPD2

3.37e-0513181882030463901
Pubmed

Human transcription factor protein interaction networks.

CUL2 SMARCA5 DNAH10 ARID4A ADRM1 ZHX2 TRRAP PIAS1 PRPF40A TLX2 NUP205 MRPL39 PSMD6 BPTF KLF10 SMARCB1 KMT2A DLAT HELZ SNRPD2 SORL1

3.39e-0514291882135140242
Pubmed

The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.

SMARCA5 TRRAP KMT2A

4.27e-0513188316510874
Pubmed

SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline.

PIWIL2 SMARCB1 DNMT3A

4.27e-0513188334912016
Pubmed

Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions.

CACNA2D1 CELF1 CELF2

5.42e-0514188328826478
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH7 DNAH12

5.42e-051418839373155
Pubmed

Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.

SMARCA5 IDH3A TRRAP PHGDH MRPL39 NFATC2 PRKDC

5.52e-05178188727637333
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

DNAH7 BPTF BAZ2A KMT2A DNAH9

5.56e-0575188525593309
Pubmed

Exome sequencing supports a de novo mutational paradigm for schizophrenia.

TRRAP PITPNM1 CELF2 PLCL2

6.49e-0540188421822266
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RNF121 SYNE1 SMC4 GEMIN5 ZHX2 ECT2 TRRAP PIAS1 CDC42BPB CCNK PHGDH MYOF NFATC2 BAZ2A TRIM32 CRACDL KMT2A HELZ CTNNA2 UTRN IQGAP3

6.58e-0514971882131527615
Pubmed

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.

SMARCA5 TRRAP KMT2A

6.74e-0515188316510875
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

ATP6V1A TBC1D15 TRPC4AP ADRM1 SYNE1 SMC4 RNF17 TRRAP PHGDH NUP205 MYOF RGS6 SNRPD2 HCCS

6.75e-057541881435906200
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

GPD2 CUL2 ECT2 PRPF40A PHGDH MYOF SUPT16H DLAT SNRPD2 IQGAP3

7.04e-054001881035013556
Pubmed

Update on the Kelch-like (KLHL) gene family.

KLHL40 IPP KLHL41 KLHL13

7.16e-0541188423676014
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

SMARCA5 CDC42BPB CCNK BPTF SUPT16H KMT2A PRKDC DNMT3A

7.18e-05251188831076518
Pubmed

A human MAP kinase interactome.

SYNE1 WWTR1 PIAS1 CDC42BPB KIAA1549L AP2B1 DIAPH2 NAV2 HELZ NKTR PRKDC

7.45e-054861881120936779
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNHD1 DNAH10 SYNE1 TRRAP MRPL39 HELZ CTNNA2

7.53e-05187188726460568
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

CUL2 TBC1D15 TRPC4AP ADRM1 SMC4 NUP205 MRPL39 PSMD6 AP2B1 PTPRM TRIM32 DHPS HELZ PRKDC UTRN SORL1

8.62e-059741881628675297
Pubmed

SORLA-mediated trafficking of TrkB enhances the response of neurons to BDNF.

NTRK2 SORL1

8.69e-053188223977241
Pubmed

TEA domain transcription factor 4 modulates repression of fetal haemoglobin by direct binding to the γ-globin gene promoters.

HBG1 HBG2

8.69e-053188234569056
Pubmed

Pitpnm1 is expressed in hair cells during development but is not required for hearing.

PITPNM2 PITPNM1

8.69e-053188223820044
Pubmed

Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins.

SMARCB1 KMT2A

8.69e-053188210490642
Pubmed

Differential segregation of beta+ IVS-I-110 (G --> A), A(gamma) -117 (G-->A), and G(gamma) -158 (C --> T) mutations in members of an Albanian family.

HBG1 HBG2

8.69e-053188214649320
Pubmed

Impact of NTRK2, DRD2 and ACE polymorphisms on prolactin levels in antipsychotic-treated patients with first-episode psychosis.

NTRK2 ACE

8.69e-053188229767567
Pubmed

Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin.

HBG1 HBG2

8.69e-053188234341563
Pubmed

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.

KMT2A PRKDC

8.69e-053188218538732
Pubmed

Promoters of the murine embryonic beta-like globin genes Ey and betah1 do not compete for interaction with the beta-globin locus control region.

HBG1 HBG2

8.69e-053188212525692
Pubmed

SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na(+)-K(+)-Cl(-) cotransporter 2.

SLC12A1 SORL1

8.69e-053188220385770
Pubmed

Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance.

KMT2A PRKDC

8.69e-053188232763164
Pubmed

Parkinson's Disease-Associated Mutant LRRK2-Mediated Inhibition of miRNA Activity is Antagonized by TRIM32.

LRRK2 TRIM32

8.69e-053188228508149
Pubmed

The ACE D/D genotype is protective against the development of idiopathic deep vein thrombosis and pulmonary embolism.

ACE F5

8.69e-053188214597977
Pubmed

Genetic influences on Alzheimer's disease: evidence of interactions between the genes APOE, APOC1 and ACE in a sample population from the South of Brazil.

APOC1 ACE

8.69e-053188221533863
Pubmed

Cloning and characterization of a novel variant (mM-rdgBbeta1) of mouse M-rdgBs, mammalian homologs of Drosophila retinal degeneration B gene proteins, and its mRNA localization in mouse brain in comparison with other M-rdgBs.

PITPNM2 PITPNM1

8.69e-053188212562526
Pubmed

Overestimation of genetic risks owing to small sample sizes in cardiovascular studies.

ACE F5

8.69e-053188212791034
Pubmed

De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells.

PRKDC DNMT3A

8.69e-053188217420264
Pubmed

The chloride effect in the human embryonic haemoglobins.

HBG1 HBG2

8.69e-05318827543751
Pubmed

Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation.

ZHX2 KMT2A

8.69e-053188219710696
Pubmed

Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice.

PIWIL2 MOV10L1

8.69e-053188227655786
Cytoband8q11

PRKDC TGS1

2.50e-04618928q11
Cytoband3p14.3

PXK DENND6A DNAH12

2.57e-043018933p14.3
GeneFamilyDyneins, axonemal

DNAH10 DNAH7 DNAH12 DNAH9

6.18e-06171334536
GeneFamilyKelch like|BTB domain containing

KLHL40 IPP KLHL41 KLHL13

2.52e-04421334617
GeneFamilyAnkyrin repeat domain containing

KRIT1 ASB18 KANK1 ANKRD20A4P MIB1 ANKRD30A MYO16 ANKRD20A1

4.27e-042421338403
GeneFamilyPhosphatidylinositol transfer proteins

PITPNM2 PITPNM1

7.90e-04613321151
GeneFamilyHemoglobin subunits

HBG1 HBG2

2.33e-03101332940
GeneFamilyUPF1 like RNA helicases

MOV10L1 HELZ

2.83e-031113321169
CoexpressionGSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_DN

TRIM72 WWTR1 RGS9 ACE EDA HOXB3 MYOF MYO16

6.34e-061371868M417
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 NTRK2 LRRK2 DNAH7 HOXB3 MYOF SLC12A1 KLHL13 UGT2B7 NAV2 IRX2

6.07e-10190189113fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 ABCA12 KCNV2 SAXO1 SLC12A1 KIAA1549L MOV10L1 CTNNA2 DNAH9

2.94e-081601899c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 ABCA12 KCNV2 SAXO1 SLC12A1 KIAA1549L MOV10L1 CTNNA2 DNAH9

2.94e-08160189925c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 PLIN4 MYOM1 KLHL40 KLHL41 ME3 ASB18 KLHDC8A MOV10L1

1.34e-0719118999d7d680da3979e256191b534ebd14c5383e0cf93
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK2 DNAH7 HOXB3 MYOF SLC12A1 KLHL13 UGT2B7 NAV2 IRX2

1.34e-0719118995a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK2 DNAH7 HOXB3 MYOF SLC12A1 KLHL13 UGT2B7 NAV2 IRX2

1.34e-07191189955ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 PLIN4 MYOM1 KLHL40 KLHL41 ME3 ASB18 KLHDC8A MOV10L1

1.34e-071911899543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 CRACDL SLC22A4 DIAPH2 DNAH9

1.60e-0719518993486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell15-Trachea|15 / Age, Tissue, Lineage and Cell class

ST6GALNAC1 CFAP43 FCGBP DNAH12 ATP2C2 HBG1 HBG2 DNAH9 MSLN

1.67e-071961899fd17403422cf95c24f6be1c2d78764bb352f7f2e
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 CRACDL SLC22A4 DIAPH2 DNAH9

1.82e-071981899ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellMild-CD4+_T|Mild / Disease group and Cell class

CYTH3 NTRK2 LRRK2 ACE EDA NEO1 CCDC62 MYO16

1.29e-061851898c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 CRACDL NAV2 DNAH9

1.92e-061951898fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 CRACDL NAV2 DNAH9

1.92e-061951898eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

DNAH10 CFAP43 DNAH7 DNAH12 CRACDL NAV2 TNFRSF19 DNAH9

1.92e-06195189821dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

NTRK2 LRRK2 HOXB3 MYOF SLC12A1 KLHL13 NAV2 IRX2

1.99e-06196189804f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

GPD2 DNAH10 GEMIN5 ECT2 SEPHS2 ANKRD20A4P GYG1 DIAPH2

1.99e-061961898b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 SLC22A4 DIAPH2 DNAH9

2.07e-061971898e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 SLC22A4 DIAPH2 DNAH9

2.07e-061971898d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 ACE BPTF PTPRM DIAPH2 KMT2A NKTR UTRN

2.32e-062001898dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TRIM72 SYCP2L ABCA2 ABCA12 MCF2L2 PNLDC1 ABCB4

2.79e-0614418973ba7f8bd6d1c551048403c94693d63e60f7cbbb7
ToppCellSevere-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PITPNM2 MYOM1 DNAH10 WWTR1 RGS9 GPD1L OTULINL

4.17e-06153189744572f87d403e314050ab935d2cd676c33d9c287
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

DNAH10 CFAP43 RNF17 DNAH12 ATP2C2 AP3M2 DNAH9

4.74e-06156189710d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TBX15 GPRASP1 CFAP43 HOXB3 DNAH12 SLC24A4 KLHDC8A

4.95e-061571897f6210be2362d833c6d869ff921188bfc85dda11d
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TBX15 GPRASP1 CFAP43 HOXB3 DNAH12 SLC24A4 KLHDC8A

4.95e-06157189743a6b423fd70479822a564ff4225a1e4951ae5ed
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Fos_(Mural.Rgs5Acta2.Fos)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TBX15 PLIN4 MYOM1 PNLDC1 ECT2 ASB18

5.78e-06105189673639bfa677c7bb9e5166aa09eabaf1b05bb89a0
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Fos_(Mural.Rgs5Acta2.Fos)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TBX15 PLIN4 MYOM1 PNLDC1 ECT2 ASB18

5.78e-06105189684b639eb44f71d1e12bb7850b9063d80e73cb741
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

ESM1 PNLDC1 DNAH12 NAV2 CD63 TNFRSF19 OTULINL

9.70e-061741897430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A PXK GPD1L HOXB3 CELF2 PLCL2 ANKRD30A

1.12e-05178189751d2188406f04329311b2efd1108fc36617a860e
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NTRK2 PTPN22 RGS9 EDA HOXB3 CRACDL CTNNA2

1.17e-051791897d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CFAP43 DNAH7 DNAH12 CRACDL SLC22A4 DNAH9

1.17e-0517918975e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH10 CFAP43 DNAH7 KIF24 HHLA2 DNAH12 DNAH9

1.25e-051811897dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 CFAP43 DNAH7 DNAH12 CRACDL SLC22A4 DNAH9

1.30e-051821897975f6275777fc578eba528e50f69891c66ec44ad
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 CFAP43 DNAH7 DNAH12 CRACDL SLC22A4 DNAH9

1.30e-051821897f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPD2 DNAH10 GEMIN5 ECT2 SEPHS2 ANKRD20A4P OTULINL

1.39e-051841897081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GPD2 DNAH10 GEMIN5 ECT2 SEPHS2 ANKRD20A4P OTULINL

1.39e-05184189784c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPD2 DNAH10 GEMIN5 ECT2 SEPHS2 ANKRD20A4P OTULINL

1.39e-051841897d31d4116d1d196633784863781fa45673607a421
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPD2 DNAH10 GEMIN5 ECT2 SEPHS2 ANKRD20A4P OTULINL

1.39e-051841897a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

GPD2 DNAH10 GEMIN5 ECT2 SEPHS2 ANKRD20A4P OTULINL

1.39e-05184189745f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KSR2 LRRK2 HOXB3 MYOF SLC12A1 KLHL13 IRX2

1.39e-0518418978fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

DNAH10 GEMIN5 SEPHS2 ANKRD20A4P OTULINL STK38L UTRN

1.39e-051841897ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SMC4 PTPN22 NFATC2 AP3M2 KMT2A NKTR TGS1

1.44e-051851897f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 CFAP43 DNAH7 HHLA2 DNAH12 TNFRSF19 DNAH9

1.44e-0518518975e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 PLIN4 MYOM1 KLHL40 KLHL41 ME3 KLHDC8A

1.49e-051861897337f768cc43db2db96ba6495b076006b1a5b0331
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 PLIN4 MYOM1 KLHL40 KLHL41 ME3 KLHDC8A

1.49e-051861897e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF RGS6 SLC12A1 CRACDL KLHL13 UGT2B7 NAV2

1.55e-05187189742a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF RGS6 SLC12A1 CRACDL KLHL13 UGT2B7 NAV2

1.55e-05187189764afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF RGS6 SLC12A1 CRACDL KLHL13 UGT2B7 NAV2

1.55e-05187189787b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

NTRK2 LRRK2 HOXB3 SLC12A1 KLHL13 NAV2 IRX2

1.55e-0518718972ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KLHL41 APOC1 ABCB4 FCGBP NFATC2 MSLN SORL1

1.55e-0518718972a7226adb4d15b92936603bdf05421c50b21f003
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 MYOM1 KLHL40 KLHL41 IDH3A ABCB4 GYG1

1.66e-051891897d2b008f98739c6af7ee63b643011a240db20e4d8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK2 LRRK2 MYOF SLC12A1 KLHL13 CTNNA2 IRX2

1.66e-051891897e059be2965cca70ff5576df055d0af1775b76e00
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK2 HOXB3 MYOF RGS6 SLC12A1 KLHL13 NAV2

1.71e-051901897bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

PITPNM2 SYCP2L SYNE1 NTRK2 ESM1 NEO1 ANKRD20A4P

1.71e-0519018977f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK2 HOXB3 MYOF RGS6 SLC12A1 KLHL13 NAV2

1.71e-051901897b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PITPNM2 SYNE1 RGS9 ACE EDA RGS6 PTPRM

1.77e-051911897f229abf69a1217194f74b0502486907e07dba989
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 NTRK2 WWTR1 ACE RGS6 PTPRM RASGRP3

1.83e-051921897c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 SLC22A4 DNAH9

1.83e-051921897be592e661367affced9ebe80849b466e6adb3a34
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 NTRK2 WWTR1 ACE RGS6 PTPRM RASGRP3

1.83e-05192189704f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SYCP2L DNAH10 TTLL5 KSR2 DNAH12 SLC12A1 MYO16

1.90e-051931897088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 SYNE1 DNAH7 HOXB3 MYOF KLHL13 UGT2B7

1.90e-05193189742df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CFAP43 DNAH7 DNAH12 CRACDL SLC22A4 DNAH9

1.90e-051931897e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 NTRK2 WWTR1 ACE RGS6 PTPRM RASGRP3

1.90e-05193189702f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

APOC1 EDA MYOF NEO1 RGS6 CELF2 KLHDC8A

1.90e-051931897cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 SYNE1 DNAH7 HOXB3 MYOF KLHL13 UGT2B7

1.90e-051931897f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 NTRK2 WWTR1 ACE RGS6 PTPRM RASGRP3

1.90e-0519318975122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 SLC22A4 DNAH9

1.90e-0519318970b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 SYNE1 LRRK2 CFAP43 DNAH7 DNAH12 IRX2

1.90e-051931897bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 LRRK2 DNAH7 HOXB3 MYOF KLHL13 UGT2B7

1.96e-051941897e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAH10 CFAP43 DNAH7 DNAH12 CRACDL SLC22A4 DNAH9

1.96e-051941897756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SMC4 DNAH7 KIF24 AP2B1 ATP2C2 IFT122 MSLN

1.96e-0519418975dffa578149104dda33774361e9e77b227b5f1ce
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH10 ABCA12 CFAP43 DNAH7 KIF24 DNAH12 DNAH9

2.03e-051951897e525b69145059b66417589601f7109af63730f3a
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 WWTR1 CFAP43 DNAH7 DNAH12 NAV2 DNAH9

2.09e-0519618976d02d494196e3f857d53eea46d9419690d43beca
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 WWTR1 CFAP43 DNAH7 DNAH12 NAV2 DNAH9

2.09e-051961897af4cdc61830685a888a1209826c23bcf54a43084
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 SLC22A4 DNAH9

2.09e-051961897d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

DNAH10 CFAP43 DNAH7 DNAH12 CRACDL NAV2 DNAH9

2.09e-05196189787d9881cfec461a5d89b688a83749b618c519485
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 SLC22A4 DNAH9

2.16e-0519718976865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 MCF2L2 CELF2 AP3M2 KMT2A NKTR UTRN

2.16e-05197189757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 DIAPH2 DNAH9

2.16e-05197189771fea4aa6ce96c7693fa94792d08770622873850
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GPRASP1 ABCA2 SYNE1 AP3M2 NKTR UTRN MYO16

2.16e-051971897e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ABCA2 SYNE1 RGS9 NFATC2 KMT2A NKTR UTRN

2.16e-051971897836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 SYNE1 CFAP43 DNAH7 HHLA2 DNAH12 DNAH9

2.16e-05197189774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid-early_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ST6GALNAC1 ENOSF1 CNRIP1 APOC1 PRKDC HBG1 HBG2

2.24e-0519818978d900a17667a41bdfa683a34275fe4c059f6a8ef
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ST6GALNAC1 DNAH10 CFAP43 DNAH7 DNAH12 ATP2C2 DNAH9

2.31e-0519918971df69c0cb5f759f6a2152521842506a75bb95cae
ToppCellMild-Epithelial-Epithelial-|Mild / Condition, Lineage, Cell class and cell subclass

ST6GALNAC1 DNAH10 CFAP43 DNAH7 DNAH12 ATP2C2 DNAH9

2.31e-05199189781115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GALNAC1 DNAH10 CFAP43 DNAH7 DNAH12 ATP2C2 DNAH9

2.31e-05199189774087b4b5e567310fc4ac58fb267ff651a180680
ToppCellMild-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ST6GALNAC1 DNAH10 CFAP43 DNAH7 DNAH12 ATP2C2 DNAH9

2.31e-051991897ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GALNAC1 DNAH10 CFAP43 DNAH7 DNAH12 ATP2C2 DNAH9

2.31e-0519918971ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ST6GALNAC1 DNAH10 CFAP43 DNAH7 DNAH12 ATP2C2 DNAH9

2.31e-05199189700b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCellMild-Epithelial-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ST6GALNAC1 DNAH10 CFAP43 DNAH7 DNAH12 ATP2C2 DNAH9

2.31e-05199189791308b255783ad4029e5575028c18d7550832c51
ToppCellMild_COVID-19-Epithelial|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ST6GALNAC1 DNAH10 CFAP43 DNAH7 DNAH12 ATP2C2 DNAH9

2.31e-05199189772689bda7476930887ae007682fcab27f956f050
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

ST6GALNAC1 DNAH10 CFAP43 DNAH7 HHLA2 DNAH12 DNAH9

2.38e-052001897f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

GPD2 DNAH10 GEMIN5 ECT2 SEPHS2 ANKRD20A4P STK38L

2.38e-052001897118321ac443feb42aee171baccfc4610f00a8822
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

PITPNM2 ACE ABCB4 BPTF PTPRM DIAPH2 NKTR

2.38e-0520018973b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

DNAH10 SYNE1 CFAP43 DNAH7 DNAH12 CRACDL DNAH9

2.38e-0520018973305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMARCA5 BPTF CELF2 KMT2A HELZ NKTR UTRN

2.38e-05200189712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellBrain_organoid-organoid_Tanaka_cellReport|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

NTRK2 WWTR1 KLHL41 APOC1 MYOF SEPHS2 CD63

2.38e-052001897b0ba486b55be18a4236bd2644f02352651f4b1fe
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK2 MYOF SLC12A1 KLHL13 NAV2 CD63 IRX2

2.38e-052001897d9dab2aed11e45c60d11ff0c5af1f2fbb9cb45d8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK2 MYOF SLC12A1 KLHL13 NAV2 CD63 IRX2

2.38e-05200189733b7af6c50e65dc1bdf429572574ed072f8bc29f
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PITPNM2 ACE BPTF PTPRM DIAPH2 NKTR UTRN

2.38e-052001897a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Mesoderm|3m / Sample Type, Dataset, Time_group, and Cell type.

TBX15 TRIM72 MYOM1 KLHL40 WWTR1 KLHL41 KIF24

2.38e-052001897538ae964db58c4acafe93f735b3e03fc08fdaac6
DiseaseFETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1

HBG1 HBG2

1.14e-0431832141749
DiseaseHereditary persistence of fetal hemoglobin

HBG1 HBG2

1.14e-0431832cv:C0019025
Diseasedelta beta-thalassemia (is_implicated_in)

HBG1 HBG2

1.14e-0431832DOID:0080773 (is_implicated_in)
DiseaseFETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1

HBG1 HBG2

2.28e-0441832C1841621
Diseasememory performance

APOC1 ZHX2 F5 PHGDH NEO1 RGS6 KIAA1549L DIAPH2 HBG2 SORL1

2.53e-0440918310EFO_0004874
DiseaseAdenocarcinoma of large intestine

TRRAP CDC42BPB GRK2 PRKDC MAP2K7

3.36e-04961835C1319315
Diseasenon-arteritic anterior ischemic optic neuropathy (is_implicated_in)

ACE F5

3.78e-0451832DOID:0050864 (is_implicated_in)
DiseaseSudden death

CACNA2D1 ACE

3.78e-0451832C0011071
DiseaseCardiac Arrhythmia

CACNA2D1 ACE GYG1

4.88e-04251833C0003811
DiseaseRHEUMATOID ARTHRITIS

PTPN22 SLC22A4

5.65e-0461832180300
DiseaseRheumatoid arthritis

PTPN22 SLC22A4

5.65e-0461832cv:C0003873
Diseasetriglycerides in small VLDL measurement

DMGDH DNAH10 APOC1 BPTF

5.67e-04611834EFO_0022145
Diseaseperipheral vascular disease

F5 KIAA1549L

7.87e-0471832EFO_0003875
DiseaseLDL cholesterol change measurement

APOC1 PKD1L3

7.87e-0471832EFO_0007804
Diseaseneuronal pentraxin-2 measurement

APOC1 F5

7.87e-0471832EFO_0801834
Diseasesurfeit locus protein 1 measurement

APOC1 F5

7.87e-0471832EFO_0802105
Diseasemetabolite measurement

DMGDH APOC1 ACE ZRANB3 PHGDH BPTF MYOF SLC22A4 UGT2B7 OTULINL SORL1

7.91e-0456018311EFO_0004725
DiseaseAlzheimer disease, family history of Alzheimer’s disease

APOC1 ACE SLC24A4 CELF1 SORL1

8.97e-041191835EFO_0009268, MONDO_0004975
Diseasebeta-defensin 119 measurement

NELFE APOC1

1.05e-0381832EFO_0801419
Diseasegrip strength measurement

PTGES2 DNAH10 CIR1 PKD1L3 BPTF HOXB3 CELF1 TECPR2

1.61e-033501838EFO_0006941
Diseasetheophylline measurement

LRRK2 NAV2

1.67e-03101832EFO_0021180
DiseaseProstatic Neoplasms

ARID4A ACE PHGDH THYN1 CELF2 BAZ2A FBXO44 KMT2A PRKDC HBG1 HBG2

1.69e-0361618311C0033578
DiseaseMalignant neoplasm of prostate

ARID4A ACE PHGDH THYN1 CELF2 BAZ2A FBXO44 KMT2A PRKDC HBG1 HBG2

1.69e-0361618311C0376358
DiseaseOther specified cardiac arrhythmias

CACNA2D1 GPD1L

2.03e-03111832C0348626
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPB KRIT1

2.03e-03111832DOID:0060669 (implicated_via_orthology)
DiseaseNodal rhythm disorder

CACNA2D1 GPD1L

2.03e-03111832C0264893
DiseaseEctopic rhythm

CACNA2D1 GPD1L

2.03e-03111832C1399226
DiseaseCARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)

CACNA2D1 GPD1L

2.03e-03111832C2748542
Diseaseserum metabolite measurement

RNF121 GPD2 ENOSF1 DMGDH CACNA2D1 NTRK2 IPP NDN APOC1 ACE PHGDH ABCB4 CELF1 SLC22A4

2.40e-0394518314EFO_0005653
Diseasetriacylglycerol 56:6 measurement

APOC1 FCGBP ATP2C2

2.41e-03431833EFO_0010433
Diseaseliver cirrhosis (is_implicated_in)

ACE F5 ABCB4

2.41e-03431833DOID:5082 (is_implicated_in)
Diseaseacute myeloid leukemia (implicated_via_orthology)

ARID4A KMT2A

2.42e-03121832DOID:9119 (implicated_via_orthology)
DiseaseThromboembolism

NTRK2 HBG1 HBG2

2.58e-03441833HP_0001907
Diseaseplatelet component distribution width

SYNE1 U2SURP LRRK2 CNRIP1 APOC1 SLC24A4 AP2B1 BAZ2A NYNRIN MOV10L1 DHPS TGS1

2.77e-0375518312EFO_0007984
Diseasexanthine measurement

KSR2 CELF2

2.85e-03131832EFO_0010548
Diseasemiddle temporal gyrus volume measurement, Alzheimer's disease biomarker measurement

KSR2 APOC1

2.85e-03131832EFO_0006514, EFO_0010316
DiseaseBrugada Syndrome 1

CACNA2D1 GPD1L

2.85e-03131832C4551804
Diseasemotion sickness

GPD2 HOXB3 CELF2

3.31e-03481833EFO_0006928
DiseaseAlzheimer's disease biomarker measurement

WWTR1 APOC1 SORL1

3.31e-03481833EFO_0006514
Diseaseamino acid measurement

CACNA2D1 GCFC2 ABCA12 SYNE1 WWTR1 DNAH7 DNAH12 TNFRSF19 PRKDC HBG2 MYO16

3.53e-0367818311EFO_0005134
DiseaseFamilial Alzheimer Disease (FAD)

APOC1 ACE CHRNB2 SORL1

3.53e-031001834C0276496
DiseaseSchizophrenia

ST6GALNAC1 NTRK2 RGS9 ACE TRRAP CHRNB2 PITPNM1 CELF2 PLCL2 KMT2A CTNNA2 MAP2K7 MYO16

3.58e-0388318313C0036341
DiseaseAlzheimer's Disease

APOC1 ACE CHRNB2 SORL1

3.66e-031011834C0002395
Diseaseopioid use disorder

PTGES2 CRACDL PLCL2 SORL1

3.66e-031011834EFO_0010702
DiseaseCrohn Disease

LRRK2 SLC22A4 DNMT3A

3.71e-03501833C0010346
DiseaseHemoglobin F Disease

HBG1 HBG2

3.81e-03151832C0019025
DiseaseSinus Node Dysfunction (disorder)

CACNA2D1 GPD1L

3.81e-03151832C0428908
Diseaseteratocarcinoma-derived growth factor 1 measurement

NTRK2 KMT2A

4.34e-03161832EFO_0008297
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

KCNV2 F5

4.34e-03161832EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Diseaseidiopathic scoliosis (implicated_via_orthology)

DNAH10 KATNB1

4.34e-03161832DOID:0060250 (implicated_via_orthology)
Diseasecentral nervous system disease (implicated_via_orthology)

SMARCA5 GEMIN5

4.34e-03161832DOID:331 (implicated_via_orthology)
Diseasemean reticulocyte volume

PLIN4 ZHX2 TRRAP ME3 ABCB4 NUP205 KLF10 AP2B1 NYNRIN PLCL2 HBG2 MYO16

4.34e-0379918312EFO_0010701
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 TRIM32

4.89e-03171832DOID:9884 (is_implicated_in)
Diseaseerythritol measurement

CACNA2D1 IPP

4.89e-03171832EFO_0021171
DiseasePsychoses, Substance-Induced

RGS9 ACE

4.89e-03171832C0033941
Diseasecopine-1 measurement

TRPC4AP CNBD2

4.89e-03171832EFO_0008102
DiseaseCongestive heart failure

APOC1 ACE GRK2 MAP2K7

4.96e-031101834C0018802
DiseaseHeart failure

APOC1 ACE GRK2 MAP2K7

4.96e-031101834C0018801
DiseaseLeft-Sided Heart Failure

APOC1 ACE GRK2 MAP2K7

4.96e-031101834C0023212
DiseaseHeart Failure, Right-Sided

APOC1 ACE GRK2 MAP2K7

4.96e-031101834C0235527
DiseaseHeart Decompensation

APOC1 ACE GRK2 MAP2K7

4.96e-031101834C1961112
DiseaseMyocardial Failure

APOC1 ACE GRK2 MAP2K7

4.96e-031101834C1959583
Diseasehippocampal atrophy

GCFC2 APOC1 F5

5.11e-03561833EFO_0005039
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

DNAH10 APOC1 BPTF NYNRIN

5.12e-031111834EFO_0004530, EFO_0008595
DiseaseTourette syndrome, schizophrenia

PITPNM2 DNAH10

5.48e-03181832EFO_0004895, MONDO_0005090
DiseaseLibman-Sacks Disease

PTPN22 PXK RASGRP3

5.64e-03581833C0242380
Diseaseadverse effect, response to xenobiotic stimulus

ABCA2 CELF2 NAV2

5.91e-03591833EFO_0009658, GO_0009410
Diseasesmoking status measurement

PTGES2 CDC42BPB ZNF518A FOCAD ASB18 BPTF HHLA2 HOXB3 CELF2 CRACDL PLCL2 NAV2 CTNNA2 UTRN SORL1

5.96e-03116018315EFO_0006527
Diseaseinferior parietal cortex volume measurement

TBC1D15 HBG2

6.10e-03191832EFO_0010307

Protein segments in the cluster

PeptideGeneStartEntry
LEMKSKTARNTPNWD

ANKRD20A1

486

Q5TYW2
KMFVGQIPRSWSEKE

CELF2

41

O95319
MAKPDAVWTEEERKQ

CFAP43

1146

Q8NDM7
KTRVVPDNWKMDISE

ARID4A

256

P29374
KMERQVFLATWKDIP

AP2B1

831

P63010
DVEWMSIFKPSKMQR

CCDC62

531

Q6P9F0
AKAVEVQNKPMIEWA

DNMT3A

396

Q9Y6K1
WNKSMLEKPTDGREV

ACE

941

P12821
IKMFVGQVPRTWSEK

CELF1

16

Q92879
REKSQEWMDKSPLFM

ABCA12

836

Q86UK0
LEMKSKTARNTPNWD

ANKRD20A4P

486

Q4UJ75
AFQEGIMSWSPKEKT

BAZ2A

1496

Q9UIF9
SSQEKDWDRKLQMAP

FAM47DP

286

A6NHR8
SAKMREWFSETFQKV

APOC1

61

P02654
MSPAKETSEKFTWAA

ANKRD30A

396

Q9BXX3
RLCKFEIQEWTSKPM

CCNK

216

O75909
RADSEKKWVYPSEQM

HCCS

111

P53701
AKFSPAMAQEKTEGW

DNHD1

1041

Q96M86
VSMKRINWSKIEPTE

DIAPH2

636

O60879
ANWIKAVQMCSKPRE

BPTF

931

Q12830
KEIPFSSEQKWMAVK

ATP2C2

481

O75185
EVKESPFFRSLDWQM

GRK2

446

P25098
KPRWEKFFMVTFITA

SLC24A4

446

Q8NFF2
VMWNSAAQTPDKKAS

RFTN2

401

Q52LD8
MSKEPSQQRVKRWGF

RGS6

321

P49758
PTKMRVERWAFNFSE

RGS9

291

O75916
FQMTSDELPKENWLK

ECT2

771

Q9H8V3
EKWVEVASMKVPRAG

IPP

511

Q9Y573
ADTTMKWQTKAFPIV

PTPN22

391

Q9Y2R2
KRWQQDMSTSVPKLF

MSL3P1

296

P0C860
KTMWERLTAPEDVFS

NUP205

1446

Q92621
YTDWEKIPSMSKNRV

CD63

151

P08962
TFDPVTKMLSWDVGK

AP3M2

331

P53677
VIEPKAMINFWSENK

OR9K2

101

Q8NGE7
PRDKILVFKDENFWM

MMP27

336

Q9H306
IWEMEATVDKDKSQP

NFATC2

621

Q13469
FEVAKMASVTGKRWP

GPD2

506

P43304
DWARNIKEPKAAVEM

IFT122

756

Q9HBG6
WVDEIQTPKARKMEF

MOV10L1

726

Q9BXT6
RKQPMLDAATGKSVW

NELFE

331

P18615
SQMIWSVESNFPKKL

MYO16

856

Q9Y6X6
LQKFASTVKMWVFEE

GPD1L

31

Q8N335
INKDEMEWQVKSPAT

ASB18

91

Q6ZVZ8
WAFEQEERPTFTKLM

KSR2

911

Q6VAB6
MATPVVTKTAWKLQE

KATNB1

1

Q9BVA0
AWKLEAFSRMEQDKV

CCNYL2

321

Q5T2Q4
DVPEAVEWMSKLAKF

ENOSF1

256

Q7L5Y1
GPWIKNMERATTSKE

MCF2L2

981

Q86YR7
ASWFKDVMAKTESPR

MAP2K7

391

O14733
PTMQAGTIARWEKKE

DLAT

101

P10515
EAMEERKKNPSWTIE

MINAR2

101

P59773
DMTKQKEFFDVWPVL

PDE6A

281

P16499
MDTTRPDIEVKDWFA

FBXO44

151

Q9H4M3
SPNQDFKVTWSRMKS

HHLA2

251

Q9UM44
EWREDMKSFIAVPVT

DNAH12

2291

Q6ZR08
TSEKQNPWTEMEKIR

KIF24

211

Q5T7B8
EWFRVSSQKSAIPAM

KANK1

1121

Q14678
VFEAVMKWVRTDKEN

KLHL41

196

O60662
KWDVMTEFPQERSSI

KLHL41

521

O60662
AEVDAMKPWLFNIKA

LRRK2

1426

Q5S007
PKQEKWQRSMSSVTE

KRIT1

266

O00522
FLKMSPEDIRKWNVT

MSLN

376

Q13421
KKFEWKELAPMQTAR

KLHL40

486

Q2TBA0
TIGDMKKPATTDVFW

KIAA1549L

386

Q6ZVL6
LEWAKPFTQLVKEMQ

CDC42BPB

56

Q9Y5S2
EEMFPKDITKWSSND

PITPNM2

356

Q9BZ72
EKWMNSLSPEKVLSE

HELZ

241

P42694
ASTDQPSWMELARKK

CRACDL

936

Q6NV74
SAMAKKQRPADTAFW

IQGAP3

656

Q86VI3
NKMTWAPRNKSEDED

IRX2

176

Q9BZI1
QGISFPSWMKEKDIV

OTULINL

151

Q9NUU6
KVDAAWEPSKNTLIM

MIB1

726

Q86YT6
DEKAATRMAPNGWKS

ABCB4

646

P21439
EKRVPSNASWEQAMK

PRPF40A

406

O75400
LNDWSRITMNPKVFK

EDA

271

Q92838
MKIFDAAKAPIQWEE

IDH3A

51

P50213
QDPDETWMFITKKQT

CD101

256

Q93033
MAQPFVSSEERKERW

GYG1

311

P46976
DTDKWIQKAPMTTVR

KLHL13

511

Q9P2N7
TAAVNSPVVSWKMKA

CTNNA2

896

P26232
STGLKEMPWFKSVEE

GCFC2

516

P16383
LPEKWFENSAMRTSI

GCFC2

706

P16383
PFPSAVTIKSWVDKM

CACNA2D1

26

P54289
SQEKPAMEKWRAQDF

FCGBP

5386

Q9Y6R7
SSSPKLQIAAMWKED

FCRL1

66

Q96LA6
VMEQNTEGVKWTPSK

DHPS

191

P49366
ECKPNETRSLMWVNK

CNRIP1

146

Q96F85
MVLSPADKTNVKAAW

HBA1;

1

P69905
KEFTPEVQASWQKMV

HBG1

121

P69891
DSAKETLLKMWFPEV

DNAH7

321

Q8WXX0
TKQIFPWMKESRQTS

HOXB3

126

P14651
MSLKPRVVDFDETWN

CUL2

1

Q13617
EWMKSIKASISRDPF

CYTH3

371

O43739
SPNFDGWFKTRRKEM

DENND6A

511

Q8IWF6
FDKMKSPFEWDIVTR

ABCA2

1976

Q9BZC7
EKMKVQDSWVTNGVP

DMGDH

316

Q9UI17
GVPKAEATRKIWMVD

ME3

356

Q16798
VIMGRKTWFSIPEKN

DHFR2

51

Q86XF0
VVKENAAGSPVMRKW

ESM1

166

Q9NQ30
MEVPNVKDFQWKRLA

KLHDC8A

1

Q8IYD2
ERPKESMYSWNKTAE

KLF10

21

Q13118
QMERVFPWFSVKKSR

KMT2A

1761

Q03164
NIMKTWVTPIFKTKD

DNAH9

816

Q9NYC9
FDGWMKIDIRPFKAS

DNAH9

1081

Q9NYC9
KETNIWTVSEKFNMP

HELQ

946

Q8TDG4
KEFTPEVQASWQKMV

HBG2

121

P69892
WKTAKGVMSDPNFLR

DNAH10

3181

Q8IVF4
WKTQAANIKSMDPAS

EFCAB3

286

Q8N7B9
PETLEQMQKVKWFRS

SLC22A4

516

Q9H015
QKFIDWLFSIMESPK

FOCAD

1751

Q5VW36
AVVEQEMKKDWLFAP

PSMD6

276

Q15008
QSAPWDSAKKDENRM

PTPRM

911

P28827
QEWFMVQTKSKPRVQ

NYNRIN

11

Q9P2P1
KAIPVSRFKEEAQMW

GPRASP1

81

Q5JY77
WTEKELQPSEKQMVS

PLIN4

61

Q96Q06
EIVRTKEFEGNMTWK

TAS2R43

151

P59537
DMKEAESVRNGWKPV

UTRN

2706

P46939
EWMPTKENLRSFTKD

MRPL39

191

Q9NYK5
DFSGDVTLTWMRPKK

SORL1

1566

Q92673
KKPRTVNVEDSWAME

TRIM32

296

Q13049
VWKKMLASVESVPFS

TRIM35

291

Q9UPQ4
ETPQETYRKVMNWKE

STK38L

326

Q9Y2H1
VMKKEPAESSFRFWQ

TRPC4AP

521

Q8TEL6
KDDYKQWSSMRTEPV

SAXO1

341

Q8IYX7
VLENVKEMWTEVPKS

SNRPD2

66

P62316
SAEPIQDWLSKTEKM

SYNE1

3181

Q8NF91
EFASKPWIQVDMQKE

F5

1956

P12259
WKPSYERIQEMKAKT

NKTR

626

P30414
DVDWNKTPKDSFTMS

PIWIL2

431

Q8TC59
FPDWTEENKVNIVKM

RASGRP3

316

Q8IV61
VTKDIWKEMNFPRVS

PNLDC1

296

Q8NA58
PSKAGTEWKLEQSMR

GOLGA8M

201

H3BSY2
LWNLMEKPFSSVAAK

KCNV2

246

Q8TDN2
DADMQSLRWEPSKKD

PLCL2

166

Q9UPR0
GDTWMRQVVSFDKLK

TBX15

206

Q96SF7
TVKWVKNGDMVIPSD

NEO1

371

Q92859
VSFQEEMKWKEDSRP

NAV2

2021

Q8IVL1
AKRDEQMRPFAVAWS

PKD1L3

931

Q7Z443
TASLMSVADPWKKIQ

SHLD2

26

Q86V20
RAAWKSPEKEKTMVN

ST6GALNAC1

121

Q9NSC7
QAKLSEMEEVKPASW

SLC38A7

416

Q9NVC3
WDMSEKENSPEKFAL

SMARCB1

281

Q12824
IRPNKESWKVFEEMI

SLC12A1

981

Q13621
ADKWVAAVGKDRPFM

PTGES2

311

Q9H7Z7
GTWAPMRSKKEVQEV

PIAS1

411

O75925
GAEWKVMSEAEKRPF

SOX1

86

O00570
NWTKIMKTIVDDPEG

SUPT16H

901

Q9Y5B9
PEVKTMTRDGEKWSQ

SUPT20HL2

176

P0C7V6
MTRDGEKWSQEDKFP

SUPT20HL2

181

P0C7V6
PTKWRTEDFRMFKNG

U2SURP

486

O15042
RLTWKPEEFDNMKKV

CHRNB2

91

P17787
GSKRLFFWMQEPKTD

ADRM1

101

Q16186
WMVDAIDPTRKQKVE

ATAD1

36

Q8NBU5
EKWRFSMPFKLAQVV

CHST3

426

Q7LGC8
IMQKKPSWRTEDEIQ

CNBD2

91

Q96M20
PASKSNIKKVWMAEQ

CIR1

16

Q86X95
IMWIKTLQEAKSSPD

NTRK2

156

Q16620
WENTEAVMKNKEKPS

PNMA5

331

Q96PV4
IEPYKRTMQWSKEAK

RNF17

796

Q9BXT8
EEVFPKEMTKWNSND

PITPNM1

361

O00562
LDNPERWNKVKMVVS

SEPHS2

266

Q99611
PLMKNFDTSQWEDIK

TRIM13

276

O60858
MTWTQVECPFEKDKK

RASGEF1A

421

Q8N9B8
PKVVDRWNEKRAMFG

MRPL51

41

Q4U2R6
WDSVTLPKEAVMNFS

SYCP2L

341

Q5T4T6
ANQRMAKFPESIKAW

GEMIN5

1441

Q8TEQ6
VSMFFRSEPKWEVVE

PXK

136

Q7Z7A4
VWAKKMTEIQTPENT

SMC4

676

Q9NTJ3
FEGVKEKFTMVQVWP

ATP6V1A

196

P38606
KEKVDLKRMFSNPWE

RNF121

276

Q9H920
APVEKVADKLRMAFW

TECPR2

1056

O15040
PIISDDFKFQVWRKM

TRIM72

266

Q6ZMU5
EKSKWEDFSNVDSPM

ZNF518A

746

Q6AHZ1
AEWDMVNTVSFKRKP

TBC1D15

96

Q8TC07
TMDVFVKEPSFDWKN

PRKDC

4001

P78527
WPEQSMKDSFQKVVL

ZNF626

86

Q68DY1
SKEDNPKWSMVDVQF

THYN1

151

Q9P016
RAWEKFNKRAETQMP

ZNF786

216

Q8N393
WSPEEVEEARKKMFN

ZHX2

321

Q9Y6X8
PKIQSMIEDAWKEGF

ZUP1

391

Q96AP4
QFMEKKPSWSLRSQD

TNFRSF19

196

Q9NS68
VPDEFSKQEKLTGMW

SLC25A23

171

Q9BV35
IPQATASMKDGKWER

PHGDH

121

O43175
EKFLTWVNKPMDEEA

TGS1

516

Q96RS0
MQQIKRWSDLPKDTF

UGT2B7

91

P16662
VPKSTLHNWMSEFKR

SMARCA5

236

O60264
QVEVSCPKEMAWKVN

TRRAP

2871

Q9Y4A5
VENTPKENSMKVREW

TTLL5

626

Q6EMB2
AKALRMTDAQVKTWF

TLX2

191

O43763
IEKITTWQDPRKAMN

WWTR1

146

Q9GZV5
NTSFEEWEKIMRTPN

ZRANB3

286

Q5FWF4
PSKAGTEWKLEQSMR

GOLGA8IP

201

A6NC78
SQGKLQMWVDVFPKS

MYOF

1756

Q9NZM1
FRDSMVLGWKQPDKI

MYOM1

946

P52179
MEFLARVFKKDPQAW

NDN

276

Q99608