Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmolecular adaptor activity

COL4A4 ATN1 COL19A1 SH2B3 DTX1 CMTM2 INSM1 NACA SH2D3C STAP2 ZC3H18 FBXL19 AXIN1 RBCK1 NCOR2 MED19 TLE4 ZNF598

8.27e-0513569718GO:0060090
GeneOntologyMolecularFunctionglutaminase activity

CAD GLS

1.39e-044972GO:0004359
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

ATN1 COL19A1 SH2B3 DTX1 CMTM2 NACA SH2D3C STAP2 ZC3H18 FBXL19 AXIN1 RBCK1 NCOR2 MED19 TLE4 ZNF598

1.40e-0411609716GO:0030674
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

SETD1B KMT2A

6.42e-048972GO:0140945
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

SETD1B KMT2A

1.02e-0310972GO:0140999
GeneOntologyMolecularFunctionunmethylated CpG binding

FBXL19 KMT2A

1.02e-0310972GO:0045322
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

FOXS1 ZNF142 ZNF48 ERF INSM1 IRX1 WIZ MZF1 SKOR2 ZNF516 TPRX1 OLIG1 MYRF FOXK1 ZNF367 SP7

1.22e-0314129716GO:0000981
MousePhenoprenatal growth retardation

CABLES2 SAMD1 SETD1B ERF NACA IRX1 FBXL19 ASAP1 AXIN1 NCOR2 ATAD3B LATS2 ATAD3A WASF2 SMN1 MYRF

1.64e-058697716MP:0010865
MousePhenoembryonic growth retardation

CABLES2 SETD1B ERF NACA IRX1 FBXL19 AXIN1 NCOR2 ATAD3B LATS2 ATAD3A WASF2 SMN1 MYRF

6.27e-057637714MP:0003984
MousePhenoabnormal embryo development

CABLES2 SAMD1 SETD1B ERF DHX37 TEDC2 NACA IRX1 ACVR2A FBXL19 AXIN1 NCOR2 ATAD3B LATS2 ATAD3A WASF2 KMT2A SMN1 MYRF

1.20e-0413707719MP:0001672
MousePhenoabnormal craniofacial morphology

SAMD1 COL7A1 ERF INSM1 IRX1 ACVR2A FBXL19 MBD6 ASAP1 AXIN1 NCOR2 SLC38A10 LATS2 MAST4 WIZ PYGO2 SKOR2 DIAPH1 KMT2A

1.22e-0413727719MP:0000428
MousePhenocraniofacial phenotype

SAMD1 COL7A1 ERF INSM1 IRX1 ACVR2A FBXL19 MBD6 ASAP1 AXIN1 NCOR2 SLC38A10 LATS2 MAST4 WIZ PYGO2 SKOR2 DIAPH1 KMT2A

1.22e-0413727719MP:0005382
DomainHMGI/Y_DNA-bd_CS

PRR12 PRB1 PRB3 PRB4

1.85e-0531964IPR000637
DomainDUF3523

ATAD3B ATAD3A

7.82e-053962PF12037
DomainDUF3523

ATAD3B ATAD3A

7.82e-053962IPR021911
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1B ZNF48 SH2B3 AKNA FBXL19 KDM6B MBD6 PRR12 SCAF1 NCOR2 SLC38A10 LATS2 WIZ ZNF516 LRP3 DMWD MYRF CEP170B FOXK1 WNK2

2.49e-111105972035748872
Pubmed

Human transcription factor protein interaction networks.

CAD ERF ATN1 VPS72 DHX37 NACA PPP1R13B ZC3H18 MBD6 PRR12 NCOR2 ATAD3B WIZ PYGO2 ATAD3A TLE4 ZNF516 KMT2A SMN1 PRRC2A FOXK1 SP7

4.88e-111429972235140242
Pubmed

Interaction network of human early embryonic transcription factors.

ERF ATN1 MBD6 PRR12 NCOR2 WIZ PYGO2 TLE4 ZNF516 TPRX1 KMT2A FOXK1

3.06e-10351971238297188
Pubmed

Molecular genetics of human salivary proteins and their polymorphisms.

PRB1 PRB3 PRB4

2.10e-0839733055850
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SAMD1 CAD ZNF48 VPS72 NACA TOM1 PRR12 SCAF1 MED19 WIZ CRACDL WASF2 KMT2A SMN1 ZNF598 PRRC2A SF3A2 CEP170B FOXK1

2.81e-081497971931527615
Pubmed

cDNA clones for mouse parotid proline-rich proteins. mRNA regulation by isoprenaline and the nucleotide sequence of proline-rich protein cDNA MP5.

PRB1 PRB3 PRB4

8.40e-0849731339347
Pubmed

The involvement of proline-rich protein Mus musculus predicted gene 4736 in ocular surface functions.

PRB1 PRB3 PRB4

8.40e-08497327588265
Pubmed

Length polymorphisms in human proline-rich protein genes generated by intragenic unequal crossing over.

PRB1 PRB3 PRB4

8.40e-0849732851479
Pubmed

Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system.

PRB1 PRB3 PRB4

4.18e-0769732993301
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CAD SETD1B VPS72 PPP1R13B ZC3H18 NCOR2 KIAA1217 ZNF516 DIAPH1 CEP170B FOXK1

7.87e-07588971138580884
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

SAMD1 SETD1B ATN1 FBXL19 MBD6 WIZ ATAD3A DIAPH1 KMT2A FOXK1

1.30e-06495971027705803
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXS1 ERF INSM1 AKNA IRX1 MZF1 SKOR2 TPRX1 KMT2A OLIG1 MYRF FOXK1 SP7

1.48e-06908971319274049
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

CAD ZC3H18 ATAD3B ATAD3A DIAPH1 KMT2A PRRC2A

1.66e-0620297724639526
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SAMD1 ERF ATN1 VPS72 ZC3H18 PRR3 SCAF1 NCOR2 ZNF469 ATAD3B WIZ DIAPH1 CEP170B FOXK1

2.66e-061116971431753913
Pubmed

Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.

CAD ATN1 ATAD3A DIAPH1 ZNF598 PRRC2A SF3A2

2.92e-0622097724550385
Pubmed

Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.

BAG3 AXIN1 ATAD3B ATAD3A ZNF598 FOXK1

6.26e-0616197636398662
Pubmed

Salivary proline-rich proteins.

PRB1 PRB4

7.70e-0629726810092
Pubmed

Identification and characterization of FBXL19 gene in silico.

FBXL19 KMT2A

7.70e-06297215547684
Pubmed

Identification of Lys-Pro-Gln as a novel cleavage site specificity of saliva-associated proteases.

PRB3 PRB4

7.70e-06297218463091
Pubmed

Enhanced glycosylation and sulfation of secretory proteoglycans is coupled to the expression of a basic secretory protein.

PRB1 PRB4

7.70e-0629729487127
Pubmed

ATAD 3A and ATAD 3B are distal 1p-located genes differentially expressed in human glioma cell lines and present in vitro anti-oncogenic and chemoresistant properties.

ATAD3B ATAD3A

7.70e-06297218639545
Pubmed

Molecular characterization of the tumor-associated antigen AAA-TOB3.

ATAD3B ATAD3A

7.70e-06297216909202
Pubmed

Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement.

CFP COLEC12

7.70e-06297232909942
Pubmed

The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization.

ATAD3B ATAD3A

7.70e-06297217210950
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ATN1 PRR12 WIZ PYGO2 TLE4 KMT2A FOXK1

1.06e-0526897733640491
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ASAP1 PRR12 ATAD3B TLE4 KIAA1217

1.07e-0510397510574462
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ATN1 BAG3 ZC3H18 CLASRP SCAF1 NCOR2 TLE4 ZNF516 KMT2A DMWD PRRC2A

1.08e-05774971115302935
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ERF ATN1 DHX37 NACA RGS3 RUSC2 PRR12 GORASP1 WASF2 KMT2A

1.42e-05650971038777146
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SAMD1 ZNF48 ERF VPS72 ZC3H18 CLASRP PRR12 SCAF1 NCOR2 WIZ ATAD3A KMT2A SF3A2 FOXK1

1.42e-051294971430804502
Pubmed

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

NACA BAG3 RGS3 RBCK1 ZNF516 PRRC2A FOXK1

1.51e-0528397721903422
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CAD RTN1 SYNGAP1 NCOR2 WIZ WASF2 KIAA1217 ZNF516 DIAPH1 PRRC2A CEP170B WNK2

1.56e-05963971228671696
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF48 ERF FBXL19 PRR3 WIZ ZNF516 SMN1 OLIG1 ZNF598 FOXK1 ZNF367

1.61e-05808971120412781
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

SAMD1 ERF PRR12 NCOR2 WIZ ZNF516 DIAPH1 FOXK1

1.63e-0539897835016035
Pubmed

Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation.

KDM6B OLIG1 MYRF

1.97e-051997323332759
Pubmed

Histone demethylase Jmjd3 regulates osteoblast differentiation via transcription factors Runx2 and osterix.

KDM6B SP7

2.31e-05397224106268
Pubmed

[ATAD3, a vital membrane-bound mitochondrial ATPase involved in tumor progression].

ATAD3B ATAD3A

2.31e-05397222192748
Pubmed

The structure and evolution of the human salivary proline-rich protein gene family.

PRB1 PRB4

2.31e-0539728422499
Pubmed

Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.

PYGO2 KMT2A

2.31e-05397226902498
Pubmed

ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.

ATAD3B ATAD3A

2.31e-05397228549128
Pubmed

BAG3 promotes autophagy and glutaminolysis via stabilizing glutaminase.

BAG3 GLS

2.31e-05397230910998
Pubmed

ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A.

ATAD3B ATAD3A

2.31e-05397222664726
Pubmed

ATAD3 is a limiting factor in mitochondrial biogenesis and adipogenesis of white adipocyte-like 3T3-L1 cells.

ATAD3B ATAD3A

2.31e-05397238923254
Pubmed

ATAD3A has a scaffolding role regulating mitochondria inner membrane structure and protein assembly.

ATAD3B ATAD3A

2.31e-05397234936866
Pubmed

Proteolytic processing of a human salivary proline-rich protein precursor by proprotein convertases.

PRB1 PRB4

2.31e-05397211422372
Pubmed

Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3.

ATAD3B ATAD3A

2.31e-05397225375035
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

SAMD1 BAG3 PRR12 NCOR2 WIZ TLE4 GLS ZNF516

2.32e-0541897834709266
Pubmed

USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.

BAG3 ATAD3B ATAD3A FOXK1

2.80e-056297431340145
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

NCOR2 ATAD3B WIZ ATAD3A ZNF516 PRRC2A CEP170B

3.37e-0532197732098917
Pubmed

Functional proteomics mapping of a human signaling pathway.

TOM1 PPP1R13B RGS3 NCOR2 MAST4 GORASP1 DIAPH1 PPP1R37 SF3A2

4.22e-0559197915231748
Pubmed

ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.

ATAD3B ATAD3A

4.60e-05497235236834
Pubmed

Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis.

ATAD3B ATAD3A

4.60e-05497236736924
Pubmed

Finding new posttranslational modifications in salivary proline-rich proteins.

PRB3 PRB4

4.60e-05497220879038
Pubmed

mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation.

WASF2 DIAPH1

4.60e-05497222179776
Pubmed

The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy.

ATAD3B ATAD3A

4.60e-05497238250153
Pubmed

Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells.

ATAD3B ATAD3A

4.60e-05497229242539
Pubmed

Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.

PPP1R13B LATS2

4.60e-05497221041411
Pubmed

HOXA9/IRX1 expression pattern defines two subgroups of infant MLL-AF4-driven acute lymphoblastic leukemia.

IRX1 KMT2A

4.60e-05497233069783
Pubmed

Understanding the Role of the SMN Complex Component GEMIN5 and Its Functional Relationship with Demethylase KDM6B in the Flunarizine-Mediated Neuroprotection of Motor Neuron Disease Spinal Muscular Atrophy.

KDM6B SMN1

4.60e-05497239337533
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

SAMD1 ZC3H18 WIZ KMT2A SMN1 SF3A2 FOXK1

4.94e-0534197732971831
Pubmed

WW domains provide a platform for the assembly of multiprotein networks.

CAD ATAD3A WASF2 DIAPH1 SF3A2

7.40e-0515497516055720
Pubmed

Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.

SETD1B KMT2A

7.66e-05597225561738
Pubmed

Expression analysis of ATAD3 isoforms in rodent and human cell lines and tissues.

ATAD3B ATAD3A

7.66e-05597224239551
Pubmed

LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction.

LATS2 PYGO2

7.66e-05597224360964
Pubmed

The intriguing heterogeneity of human salivary proline-rich proteins: Short title: Salivary proline-rich protein species.

PRB3 PRB4

7.66e-05597226375204
Pubmed

HPV status-independent association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18, EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas.

IRX1 SKOR2

7.66e-05597220029986
Pubmed

ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels.

ATAD3B ATAD3A

7.66e-05597229898916
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

PRR12 NCOR2 WIZ FOXK1

8.82e-058397428794006
Pubmed

Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes.

ASAP1 ATAD3A DIAPH1

8.93e-053197319041431
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

CAD ERF BAG3 ZC3H18 ASAP1 NCOR2 ATAD3A DIAPH1 PRRC2A

9.25e-0565597935819319
Pubmed

Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination.

OLIG1 MYRF SP7

9.84e-053297326928066
Pubmed

AATYK is a Novel Regulator of Oligodendrocyte Differentiation and Myelination.

OLIG1 MYRF

1.15e-04697229556912
Pubmed

Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF.

ASAP1 AXIN1

1.15e-04697218786926
Pubmed

Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation.

ATAD3B ATAD3A

1.15e-04697231472450
Pubmed

The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1.

PPP1R13B LATS2

1.15e-04697221041410
Pubmed

The role of effectors of the activin signalling pathway, activin receptors IIA and IIB, and Smad2, in patterning of tooth development.

IRX1 ACVR2A

1.15e-04697211714685
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

DHX37 ZC3H18 PRR12 ATAD3B WIZ ATAD3A KMT2A SMN1 PRRC2A SF3A2

1.30e-04847971035850772
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

COL4A4 SAMD1 VPS72 TOM1 COLEC12 SKOR2 GLS ZNF516 FOXK1

1.35e-0468997936543142
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CAD VPS72 BAG3 PPP1R13B WIZ KMT2A ZNF598 PRRC2A

1.55e-0454997838280479
Pubmed

Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors.

ATN1 NCOR2

1.60e-04797216481466
Pubmed

Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein.

OLIG1 MYRF

1.60e-04797230249802
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CAD TOM1 RTN1 ASAP1 SYNGAP1 ATAD3B ATAD3A CRACDL KIAA1217 KMT2A PRRC2A CEP170B WNK2

1.72e-041431971337142655
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

ATN1 VPS72 NACA BAG3 PRR12 WIZ KMT2A

1.93e-0442597724999758
Pubmed

A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.

ERF IRX1 OLIG1 FOXK1

1.96e-0410297419741146
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ATN1 DTX1 ASAP1 SYNGAP1 NCOR2 ZNF469 WNK2

2.08e-0443097735044719
Pubmed

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.

ATAD3B ATAD3A

2.13e-04897230914652
Pubmed

Atad3 function is essential for early post-implantation development in the mouse.

ATAD3B ATAD3A

2.13e-04897223372768
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

SETD1B KMT2A

2.13e-04897223130995
Pubmed

Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5.

GDF5 ACVR2A

2.13e-0489728702914
Pubmed

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.

SETD1B KMT2A

2.13e-04897222266653
Pubmed

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.

PYGO2 TLE4

2.13e-04897228296634
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

VPS72 ZC3H18 KMT2A

2.23e-044297335705031
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

SAMD1 ASAP1 ATAD3A PRRC2A

2.44e-0410897419531213
Pubmed

A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.

CAD DHX37 ATAD3A

2.56e-044497326471122
Pubmed

Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation.

GDF5 ACVR2A

2.74e-04997227030100
Pubmed

Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.

SETD1B KMT2A

2.74e-04997222665483
Pubmed

New insights into the molecular mechanism of multiple synostoses syndrome (SYNS): mutation within the GDF5 knuckle epitope causes noggin-resistance.

GDF5 ACVR2A

2.74e-04997221976273
Pubmed

Gene and cluster-specific expression of the Iroquois family members during mouse development.

GDF5 IRX1

2.74e-04997211520674
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZNF48 VPS72 ZC3H18 NCOR2 ATAD3B MED19 WIZ ATAD3A KMT2A PRRC2A

3.36e-04954971036373674
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CAD NACA RTN1 ASAP1 SYNGAP1 ATAD3B ATAD3A KIAA1217 GLS CEP170B WNK2

3.37e-041139971136417873
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

FBXL19 KMT2A

3.41e-041097229276034
InteractionTOP3B interactions

NUDT19 CAD SETD1B ZNF48 SH2B3 AKNA FBXL19 KDM6B MBD6 PRR12 SCAF1 NCOR2 SLC38A10 LATS2 WIZ ATAD3A ZNF516 LRP3 DMWD ZNF598 MYRF PRRC2A CEP170B FOXK1 WNK2

1.47e-0814709625int:TOP3B
InteractionNCK2 interactions

ATN1 GGN FBXL19 MBD6 ASAP1 AXIN1 SYNGAP1 WASF2 KIAA1217 PRRC2A SF3A2

4.83e-082629611int:NCK2
InteractionSP7 interactions

CAD ATN1 PRR12 NCOR2 WIZ PYGO2 ATAD3A TLE4 ZNF516 FOXK1 SP7

2.17e-073049611int:SP7
InteractionTLX1 interactions

ATN1 PRR12 NCOR2 WIZ PYGO2 TLE4 ZNF516 FOXK1

1.91e-06175968int:TLX1
InteractionTLX2 interactions

DHX37 PRR12 NCOR2 WIZ PYGO2 ATAD3A TLE4

5.25e-06142967int:TLX2
InteractionKLF15 interactions

ERF VPS72 PRR12 NCOR2 PYGO2 ATAD3A ZNF516 PRRC2A FOXK1

1.01e-05290969int:KLF15
InteractionSOX5 interactions

VPS72 NCOR2 PYGO2 ATAD3A PRRC2A FOXK1 SP7

1.25e-05162967int:SOX5
InteractionTBR1 interactions

PRR12 NCOR2 PYGO2 TLE4 FOXK1 SP7

1.67e-05113966int:TBR1
InteractionEGR2 interactions

ATN1 DTX1 PRR12 NCOR2 WIZ PYGO2 KMT2A

1.77e-05171967int:EGR2
InteractionTBXT interactions

CAD ATN1 PRR12 NCOR2 WIZ TLE4

1.94e-05116966int:TBXT
InteractionCRX interactions

ERF ATN1 PRR12 NCOR2 MYO15B WIZ PYGO2 FOXK1

2.91e-05254968int:CRX
InteractionPAX9 interactions

ATN1 PRR12 NCOR2 PYGO2 TLE4 FOXK1

3.70e-05130966int:PAX9
InteractionYWHAZ interactions

CAD SH2B3 TEDC2 BAG3 SH2D3C ZC3H18 RGS3 RUSC2 SYNGAP1 LATS2 MAST4 KMT2A DMWD ZNF598 PRRC2A CEP170B FOXK1 WNK2

4.46e-0513199618int:YWHAZ
InteractionFEV interactions

VPS72 PRR12 NCOR2 WIZ TLE4 KMT2A FOXK1

5.30e-05203967int:FEV
InteractionGSC interactions

ATN1 PRR12 NCOR2 TLE4 ZNF516

5.99e-0587965int:GSC
InteractionPAX6 interactions

INSM1 RGS3 PRR12 NCOR2 WIZ TLE4 ZNF516 DIAPH1 FOXK1

6.29e-05366969int:PAX6
InteractionPRMT2 interactions

SAMD1 SETD1B ERF KDM6B PRRC2A

7.43e-0591965int:PRMT2
InteractionTLX3 interactions

SYNGAP1 PRR12 NCOR2 WIZ PYGO2 ATAD3A TLE4 FOXK1

7.58e-05291968int:TLX3
InteractionRERE interactions

SETD1B ATN1 KMT2A PRRC2A SP7

8.24e-0593965int:RERE
InteractionYWHAE interactions

CAD SH2B3 BAG3 ZC3H18 MBD6 RGS3 RUSC2 SYNGAP1 NCOR2 MAST4 KMT2A DMWD ZNF598 PRRC2A CEP170B FOXK1 WNK2

8.30e-0512569617int:YWHAE
InteractionKLF3 interactions

VPS72 MBD6 NCOR2 WIZ ZNF516 KMT2A FOXK1

1.10e-04228967int:KLF3
InteractionPHF20 interactions

SETD1B ATN1 KDM6B KMT2A

1.18e-0453964int:PHF20
InteractionKDM1A interactions

SAMD1 TEDC2 INSM1 BAG3 PRR12 NCOR2 WIZ TLE4 KIAA1217 GLS ZNF516 SMN1 ZNF598 SP7

1.43e-049419614int:KDM1A
InteractionKLF8 interactions

VPS72 PRR12 NCOR2 WIZ ATAD3A ZNF516 PRRC2A FOXK1

1.77e-04329968int:KLF8
InteractionPNMA2 interactions

KDM6B AXIN1 ATAD3B LATS2 WIZ PRRC2A CEP170B

1.99e-04251967int:PNMA2
CytobandEnsembl 112 genes in cytogenetic band chr19q13

NUDT19 ERF GGN CLASRP PRR12 SCAF1 MZF1 PPP1R37 LRP3 TPRX1 DMWD

4.48e-0511929711chr19q13
Cytoband12p13.2

PRB1 PRB3 PRB4

1.22e-044597312p13.2
Cytoband12q24

SH2B3 NCOR2

1.28e-032597212q24
CytobandEnsembl 112 genes in cytogenetic band chr12q24

SETD1B SH2B3 DHX37 DTX1 NCOR2

1.92e-03415975chr12q24
CytobandEnsembl 112 genes in cytogenetic band chr16q24

ZC3H18 ZNF469 DNAAF1

3.06e-03136973chr16q24
Cytoband19q13.11

NUDT19 LRP3

4.12e-034597219q13.11
Cytoband9q32

AKNA RGS3

4.49e-03479729q32
GeneFamilyProline rich proteins

PRB1 PRB3 PRB4

1.06e-066693972
GeneFamilyCollagens

COL4A4 COL7A1 COL19A1

7.18e-0446693490
GeneFamilyZinc fingers CXXC-type

FBXL19 KMT2A

9.24e-0412692136
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF142 ZNF48 ZNF469 WIZ MZF1 ZNF516 ZNF598 ZNF367 SP7

1.57e-0371869928
CoexpressionGINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN

ATN1 FBXL19 CLASRP SCAF1 ATAD3B ATAD3A DMWD ZNF598 PRRC2A

4.68e-06338979M17094
CoexpressionAtlasfacebase_RNAseq_e9.5_OlfPlac_2500_K3

CAD SETD1B ZNF48 DTX1 TEDC2 ACVR2A FBXL19 RTN1 PRR12 SCAF1 SLC38A10 WIZ PYGO2 TLE4 SMN1 MMP15 PRRC2A SF3A2 WNK2 ZNF367

2.80e-0711879620facebase_RNAseq_e9.5_OlfPlac_2500_K3
CoexpressionAtlasfacebase_RNAseq_e9.5_MandArch_2500_K3

SAMD1 CAD ZNF48 ERF DHX37 TEDC2 BAG3 FBXL19 PRR12 SCAF1 WIZ PYGO2 ZNF516 LRP3 SMN1 MYRF PRRC2A SF3A2

1.20e-0512599618facebase_RNAseq_e9.5_MandArch_2500_K3
CoexpressionAtlassalivary gland

GDF5 IRX1 PRB1 PRB3 PRB4

3.74e-0583965salivary gland
CoexpressionAtlasfacebase_RNAseq_e9.5_MaxArch_2500_K4

SAMD1 CAD ERF TEDC2 CFP FBXL19 RTN1 PRR12 SLC38A10 WIZ ATAD3A ZNF516 LRP3 DMWD PRRC2A SF3A2

4.19e-0511259616facebase_RNAseq_e9.5_MaxArch_2500_K4
CoexpressionAtlasfacebase_RNAseq_e9.5_MaxArch_2500

SAMD1 CAD ERF TEDC2 SH2D3C CFP FBXL19 RTN1 PRR12 SLC38A10 WIZ ATAD3A ZNF516 LRP3 DMWD PRRC2A SF3A2

1.28e-0413719617facebase_RNAseq_e9.5_MaxArch_2500
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A4 IRX1 FBXL19 GORASP1 RNF39 MYRF

2.67e-0617997688dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A4 IRX1 FBXL19 GORASP1 RNF39 MYRF

2.67e-06179976daf8189a22786171e2b629261cf720736aa4ebdb
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERF ATN1 KDM6B NCOR2 PRRC2A SF3A2

3.33e-06186976bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERF ATN1 KDM6B NCOR2 PRRC2A SF3A2

3.65e-06189976965e0e388251e7318f8b463816dc96ccb4658677
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD INSM1 SLC38A10 ZNF516 LRP3 CEP170B

4.12e-06193976471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD INSM1 SLC38A10 ZNF516 LRP3 CEP170B

4.12e-06193976fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD INSM1 SLC38A10 ZNF516 LRP3 CEP170B

4.24e-061949763a3ecedcdc7691cf21775818b598208fcb980c29
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

COL19A1 PPP1R13B RGS3 MAST4 MYO18B WNK2

4.24e-0619497689812fb164065041357bb37a3c2d87028ec3de4e
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

COL19A1 PPP1R13B RGS3 MAST4 MYO18B WNK2

4.24e-06194976c3535f7cc0076653c72db582047cff053c322397
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD INSM1 SLC38A10 ZNF516 LRP3 CEP170B

4.24e-061949760b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-OPC_related-OPC|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ERF PPP1R13B MAST4 PPP1R37 MYO18B OLIG1

4.91e-06199976c0dc14fb9899d4263264347436de121814441dfb
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-OPC_related|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ERF PPP1R13B MAST4 PPP1R37 MYO18B OLIG1

4.91e-061999769bc53ff93ca97af4ee0f01c74a567987a26abb18
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

BAG3 SH2D3C PPP1R13B MAST4 KIAA1217 KMT2A

5.05e-062009766f531a418ff25b59a543800cf4bce7b72404ce08
ToppCellVE-CD8-naive_CD4|VE / Condition, Cell_class and T cell subcluster

STAP2 PRR3 MED19 ZNF516 VPS37D

2.64e-05160975255d2a150bfe19ee3d4d34533feb9c37ce73d225
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 SH2D3C ASAP1 COLEC12 HS3ST4

2.98e-05164975a784f47f67a5eda84d58ad7d9400e3978edbb487
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 SH2D3C ASAP1 COLEC12 HS3ST4

2.98e-051649751a1795969673232191425dde84ab24ee6a98143f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 SH2D3C ASAP1 COLEC12 HS3ST4

2.98e-051649758f074940afdbda88a4b697a7ddc687e09a4b818b
ToppCellCOVID-CD8-exh_CD4|COVID / Condition, Cell_class and T cell subcluster

NUDT19 ZNF48 CMTM2 PPP1R37 SF3A2

3.15e-051669754ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COL7A1 CAD ACVR2A RUSC2 ATAD3A

4.40e-051789759d575902d3dbe33437c9d4200df093a741269803
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

MAST4 KIAA1217 HS3ST4 RNF39 WNK2

4.40e-0517897535a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAST4 KIAA1217 HS3ST4 RNF39 WNK2

4.64e-05180975b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 SH2D3C ASAP1 COLEC12 HS3ST4

4.89e-0518297541b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 SH2D3C ASAP1 COLEC12 HS3ST4

4.89e-051829755e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 SH2D3C ASAP1 COLEC12 HS3ST4

4.89e-05182975b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIM2 IRX1 KDM6B RTN1 GLS

4.89e-05182975f5f42e23832d0210560009ce6fd8eee89751e252
ToppCellSerous|World / shred by cell class for bronchial biopsy

RTN1 PRB1 PRB3 PRB4 WNK2

5.15e-0518497509d0d1525c11dd326efd942684c03f79d992cf3b
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RTN1 PRB1 PRB3 PRB4 WNK2

5.15e-05184975f0cbb5b76e092be4188a9804ef5cf7a83cd7644f
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RTN1 PRB1 PRB3 PRB4 WNK2

5.15e-051849755433ba7bbab553ff668619822d1a9208e15cd59f
ToppCellfacs-Bladder-nan-18m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERF KDM6B RTN1 OLIG1 SF3A2

5.28e-051859753e00879466e626aa8604efecfc4678d64f54dbfc
ToppCellfacs-Bladder-nan-18m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERF KDM6B RTN1 OLIG1 SF3A2

5.28e-051859753dc5812c961ff209f197ff4cbfb90009c0537550
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

PPP1R13B RGS3 MAST4 MYO18B WNK2

6.15e-051919755d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAST4 KIAA1217 HS3ST4 RNF39 WNK2

6.15e-0519197523776c7302cead3881b39127398f3b3e0d27885e
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERF ATN1 BAG3 KDM6B NCOR2

6.15e-051919758691eba35793e4e90f93d50c2145847ee51289f7
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A4 PPP1R13B MAST4 KIAA1217 MYRF

6.46e-05193975a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCelldroplet-Kidney-KIDNEY-1m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT19 COL4A4 PPP1R13B IRX1 GLS

6.61e-05194975837cee7e6147d92a2f4b86f1ed761a9bfe65b61d
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAP2 IRX1 CRACDL MMP15 CEP170B

6.61e-051949750ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCellproximal-Epithelial-Serous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RTN1 PRB1 PRB3 PRB4 VPS37D

6.78e-0519597506b73abc1f32543f2a51db52dc6424a2a398fe0f
ToppCellproximal-Epithelial-Serous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RTN1 PRB1 PRB3 PRB4 VPS37D

6.78e-05195975cb62f04f0e45bfb36eed2e7a3fc54d6d390b2ed1
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAST4 KIAA1217 HS3ST4 RNF39 WNK2

6.78e-05195975dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellproximal-3-Epithelial-Serous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RTN1 PRB1 PRB3 PRB4 VPS37D

6.78e-0519597524a6a566143b04e37ad002e4c55037a0460ac2ef
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRB1 PRB3 PRB4 RNF39 WNK2

7.11e-05197975e2c820c4e4a6cd01ceb020473286e3f5d4e3718e
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

COL7A1 PRB3 PRB4 KIAA1217 RNF39

7.28e-05198975f5b7013045b61fc56894f80092f799770dde1c8f
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

SH2D3C MAST4 TLE4 KIAA1217 KMT2A

7.64e-05200975edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

ATN1 INSM1 KDM6B KMT2A WNK2

7.64e-05200975c92e4fc0442404481fcac623d691dae6215b852d
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RTN1 PRB3 PRB4 CRACDL WNK2

7.64e-052009757c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RTN1 PRB1 PRB3 PRB4 WNK2

7.64e-05200975a3e044468de437948b63c517e0a4773cc247c906
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

ZNF142 PIM2 TEDC2 ACVR2A AXIN1 WIZ CEP170B

1.84e-051929772450_DN
DrugHesperidin [520-26-3]; Down 200; 6.6uM; MCF7; HT_HG-U133A

SH2B3 PPP1R13B MAST4 MZF1 KMT2A DNAAF1 DMWD

2.03e-051959775313_DN
Drug(+,-)-Synephrine [94-07-5]; Up 200; 24uM; PC3; HT_HG-U133A

COL7A1 RUSC2 MZF1 DIAPH1 DMWD MYRF SF3A2

2.17e-051979777150_UP
DrugDoxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

TEDC2 TOM1 DIAPH1 KMT2A MMP15 PRRC2A SF3A2

2.17e-051979777195_DN
DrugHydroflumethiazide [135-09-1]; Up 200; 12uM; PC3; HT_HG-U133A

PPP1R13B KDM6B RUSC2 NCOR2 TLE4 DIAPH1 MYRF

2.17e-051979777259_UP
Drugrosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A

ASAP1 RBCK1 NCOR2 WIZ GLS ZNF516 MMP15

2.24e-051989776992_UP
DrugPantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; PC3; HT_HG-U133A

GDF5 COL7A1 CFP MAST4 PRB4 TLE4 MYRF

2.24e-051989774189_UP
Drug2-propylpentanoic acid; Down 200; 10000uM; MCF7; HG-U133A

ZNF142 SETD1B ATN1 NACA AXIN1 MZF1

1.55e-04188976345_DN
DrugThioguanosine [85-31-4]; Up 200; 12.6uM; MCF7; HT_HG-U133A

GDF5 COL7A1 NACA CFP MAST4 GLS

1.64e-041909762619_UP
Drug5279552; Up 200; 22uM; MCF7; HT_HG-U133A_EA

RBCK1 MAST4 DIAPH1 DNAAF1 MMP15 SF3A2

1.74e-04192976960_UP
Drugbromophenol blue

SH2B3 PRB3 PRRC2A

1.82e-0426973CID000008272
DrugIndoprofen [31842-01-0]; Down 200; 14.2uM; PC3; HT_HG-U133A

ATN1 TOM1 KDM6B MZF1 LRP3 SF3A2

1.84e-041949764249_DN
DrugEstropipate [7280-37-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A

COL7A1 ATN1 TOM1 RGS3 MZF1 GLS

1.84e-041949766068_DN
DrugOxethazaine [126-27-2]; Down 200; 8.6uM; PC3; HT_HG-U133A

ATN1 TOM1 KDM6B WIZ MYRF SF3A2

1.84e-041949764246_DN
DrugSertaconazole nitrate [99592-39-9]; Down 200; 8uM; MCF7; HT_HG-U133A

PIM2 RGS3 MAST4 MZF1 ZNF516 DIAPH1

1.84e-041949766811_DN
Drugradicicol; Down 200; 0.1uM; MCF7; HG-U133A

ZNF142 TEDC2 KDM6B WIZ GLS SF3A2

1.89e-04195976489_DN
DrugFillalbin [4540-25-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A

ATN1 MAST4 WIZ GLS DNAAF1 MMP15

1.89e-041959762813_DN
DrugAcacetin [480-44-4]; Down 200; 14uM; PC3; HT_HG-U133A

ATN1 TOM1 MAST4 TLE4 PRRC2A SF3A2

1.89e-041959764324_DN
DrugMetergoline [17692-51-2]; Down 200; 10uM; PC3; HT_HG-U133A

TLE4 LRP3 KMT2A MYRF SF3A2 CEP170B

1.94e-041969766744_DN
DrugIsoconazole [27523-40-6]; Down 200; 9.6uM; PC3; HT_HG-U133A

PIM2 RUSC2 MAST4 MZF1 TLE4 KMT2A

1.94e-041969762056_DN
DrugParbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A

COL7A1 ATN1 PIM2 KDM6B MAST4 GLS

1.94e-041969763881_DN
DrugEpiandrosterone [481-29-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A

SETD1B WIZ DIAPH1 DMWD MMP15 SF3A2

1.94e-041969763306_DN
DrugErythromycin [114-07-8]; Up 200; 5.4uM; HL60; HG-U133A

ZNF142 TEDC2 TOM1 STAP2 KDM6B AXIN1

1.94e-041969762010_UP
DrugAcacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A

ATN1 KDM6B AXIN1 WIZ PPP1R37 PRRC2A

1.94e-041969763849_UP
DrugLobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; HL60; HG-U133A

ATN1 ACVR2A RGS3 WIZ GLS MYRF

1.94e-041969761770_UP
DrugAdamantamine fumarate [80789-67-9]; Up 200; 9.6uM; HL60; HT_HG-U133A

TEDC2 CLASRP WIZ MZF1 SF3A2 CEP170B

1.94e-041969761344_UP
DrugPivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

AXIN1 GLS LRP3 DMWD MMP15 SF3A2

1.94e-041969766014_DN
DrugEtodolac [41340-25-4]; Up 200; 14uM; MCF7; HT_HG-U133A

RTN1 RUSC2 NCOR2 GLS KMT2A DMWD

1.94e-041969762254_UP
DrugProcarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; MCF7; HT_HG-U133A

PIM2 SH2B3 RGS3 RUSC2 LRP3 MMP15

1.94e-041969763533_DN
Drug0316684-0000 [391209-55-5]; Up 200; 10uM; MCF7; HT_HG-U133A

AXIN1 MAST4 WIZ MZF1 ZNF516 DNAAF1

2.00e-041979767052_UP
DrugLysergol [602-85-7]; Down 200; 15.8uM; PC3; HT_HG-U133A

COL7A1 RUSC2 NCOR2 GLS DMWD MYRF

2.00e-041979766621_DN
DrugDiazoxide [364-98-7]; Down 200; 17.4uM; PC3; HT_HG-U133A

COL7A1 ERF TEDC2 KDM6B RUSC2 MAST4

2.00e-041979765810_DN
DrugGliclazide [21187-98-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A

SH2B3 KDM6B MAST4 ZNF516 LRP3 DMWD

2.00e-041979762870_DN
DrugFlecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A

ATN1 RUSC2 MAST4 WIZ SF3A2 CEP170B

2.00e-041979763937_DN
Drugchlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A

CAD ATN1 KDM6B RUSC2 TLE4 GLS

2.00e-041979766936_UP
DrugQuipazine dimaleate salt [4774-24-7]; Down 200; 9uM; HL60; HG-U133A

SETD1B PIM2 NCOR2 WIZ SF3A2 CEP170B

2.00e-041979761789_DN
DrugOfloxacin [82419-36-1]; Down 200; 11uM; PC3; HT_HG-U133A

ZNF142 TEDC2 MAST4 WIZ MZF1 MYRF

2.05e-041989767372_DN
DrugGlafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A

COL7A1 SH2B3 MAST4 GLS MMP15 PRRC2A

2.05e-041989767018_UP
DrugRamipril [87333-19-5]; Down 200; 9.6uM; PC3; HT_HG-U133A

ZNF142 SETD1B TEDC2 WIZ TLE4 SF3A2

2.05e-041989767144_DN
DrugKetotifen fumarate [34580-14-8]; Down 200; 9.4uM; MCF7; HT_HG-U133A

PIM2 RBCK1 WIZ DIAPH1 DNAAF1 MMP15

2.05e-041989767199_DN
DrugEtodolac [41340-25-4]; Down 200; 14uM; MCF7; HT_HG-U133A

ERF TEDC2 KDM6B TLE4 PRRC2A SF3A2

2.05e-041989767006_DN
DrugDicumarol [66-76-2]; Up 200; 11.8uM; PC3; HT_HG-U133A

COL4A4 MAST4 WIZ ZNF516 DNAAF1 MMP15

2.05e-041989763766_UP
DrugBisoprolol fumarate; Down 200; 9uM; HL60; HT_HG-U133A

COL7A1 ERF KDM6B WIZ MZF1 KMT2A

2.05e-041989761287_DN
DrugRifampicin [13292-46-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A

PIM2 TOM1 RGS3 MZF1 DNAAF1 PRRC2A

2.05e-041989762847_DN
DrugCyclacillin [3485-14-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A

ATN1 PIM2 MAST4 WIZ GLS MMP15

2.05e-041989763882_DN
DrugFamprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

ATN1 WIZ TLE4 GLS LRP3 KMT2A

2.11e-041999763928_DN
DrugVidarabine [5536-17-4]; Down 200; 15uM; MCF7; HT_HG-U133A

RGS3 AXIN1 WIZ MZF1 LRP3 PRRC2A

2.11e-041999767203_DN
Drugalpha-Santonin [481-06-1]; Down 200; 16.2uM; PC3; HT_HG-U133A

ERF PIM2 TOM1 KDM6B RUSC2 CEP170B

2.11e-041999764531_DN
DrugAmoxapine [14028-44-5]; Up 200; 12.8uM; PC3; HG-U133A

ATN1 PIM2 RGS3 RUSC2 MAST4 LRP3

2.11e-041999761931_UP
DrugTinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A

SH2B3 KDM6B GLS PRRC2A SF3A2 CEP170B

2.11e-041999763430_DN
DrugAtropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A

SH2B3 AXIN1 RBCK1 MAST4 TLE4 GLS

2.11e-041999767219_DN
Drug2-propylpentanoic acid; Down 200; 50uM; MCF7; HG-U133A

COL7A1 TEDC2 RGS3 AXIN1 MZF1 PPP1R37

2.11e-04199976348_DN
DrugGuanadrel sulfate [22195-34-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A

SH2B3 TEDC2 WIZ GLS DIAPH1 PRRC2A

2.17e-042009763438_DN
DrugPalmatine chloride [3486-67-7]; Down 200; 10.4uM; PC3; HT_HG-U133A

COL7A1 ATN1 AXIN1 NCOR2 MAST4 KMT2A

2.17e-042009766612_DN
Diseaseleft ventricular diastolic function measurement

SH2B3 BAG3 RNF39 SP7

2.94e-0554964EFO_0008204
Diseaseneuromuscular disease (implicated_via_orthology)

ATAD3B ATAD3A

6.26e-054962DOID:440 (implicated_via_orthology)
DiseaseSpinal Muscular Atrophy

ATAD3A SMN1

1.04e-045962C0026847
Diseasecortical surface area measurement

GDF5 ACVR2A MBD6 PRR3 AXIN1 COLEC12 ZNF469 MAST4 TLE4 GLS OLIG1 PRRC2A WNK2 SP7

1.13e-0413459614EFO_0010736
Diseasemean corpuscular hemoglobin concentration

FOXS1 SETD1B ATN1 PIM2 SH2B3 AXIN1 COLEC12 KIAA1217 MYRF VPS37D ZNF367 SP7

2.47e-0411059612EFO_0004528
Diseasemyelofibrosis (is_implicated_in)

SH2B3 KMT2A

2.90e-048962DOID:4971 (is_implicated_in)
DiseaseQRS-T angle

NACA KMT2A MYO18B MMP15

4.05e-04106964EFO_0020097
Diseasetotal blood protein measurement

CABLES2 SH2B3 FBXL19 RGS3 COLEC12 NCOR2 TLE4

6.71e-04449967EFO_0004536
DiseaseSmall cell carcinoma of lung

INSM1 KMT2A MYO18B

7.34e-0454963C0149925
DiseaseGlobal developmental delay

ZNF142 ATN1 PRR12 DIAPH1

9.51e-04133964C0557874
Diseasesyndrome (implicated_via_orthology)

ATAD3B ATAD3A

1.55e-0318962DOID:225 (implicated_via_orthology)
Diseaseelectrocardiography

BAG3 MED19 MAST4 MYO18B MMP15 MYRF ZNF367

1.75e-03530967EFO_0004327
DiseaseR-warfarin measurement

ZNF142 PTCHD3 RGS3 RUSC2 MYO18B

1.77e-03265965EFO_0803324
Diseaseapolipoprotein A 1 measurement

COL7A1 VPS72 SH2B3 AKNA NCOR2 KMT2A MYRF FOXK1 SP7

1.79e-03848969EFO_0004614
Diseasedyslexia

SH2B3 SCAF1 MYO18B HS3ST4

1.96e-03162964EFO_0005424
Diseaseaspartate aminotransferase measurement

SH2B3 BAG3 AKNA ZC3H18 NCOR2 TLE4 MMP15 PRRC2A WNK2

2.75e-03904969EFO_0004736
DiseaseQRS duration

NACA BAG3 SKOR2 KMT2A MYRF

2.94e-03298965EFO_0005055

Protein segments in the cluster

PeptideGeneStartEntry
PAPPKPEPGEAPGAS

ERF

461

P50548
PKGEGAGPPPPLPPA

ATAD3A

11

Q9NVI7
QDPGPPPPSPLLGLK

ACVR2A

176

P27037
GLPPGPEKGPTLAPS

ATN1

341

P54259
KPGSPTVGPGPLPPA

ATN1

686

P54259
PPLPLKGPPGDPGFP

COL4A4

361

P53420
KGSSPVGPPGPPGSP

COL4A4

736

P53420
PKDIPDPGPPGDQGP

COL4A4

1251

P53420
KEPASGPPAPGKPPH

CEP170B

871

Q9Y4F5
GGTAIPPPPPLPGSA

DIAPH1

671

O60610
PPAGPGPGPALPAVR

DMWD

81

Q09019
PPAGPPAFPAGDSKP

PPP1R13B

531

Q96KQ4
KGPLPAGPPPEDVPG

FBXL19

196

Q6PCT2
GSPPGPDAPPSKDVP

RGS3

751

P49796
PPAAPAAPGPKDGPG

GLS

96

O94925
GPKPPATLGADGPPP

NCOR2

766

Q9Y618
EGGAEPKDPPPPGPH

MBD6

921

Q96DN6
KLPPRPGGPEPKPGH

GDF5

96

P43026
PGGPEPKPGHPPQTR

GDF5

101

P43026
SPPGPAPGPGLALEP

NUDT19

146

A8MXV4
PGPPGKAEPSLPAPN

LATS2

416

Q9NRM7
GPLEPGPPKPGVPQE

RBCK1

166

Q9BYM8
GGKPERPPKPGPPVQ

MMP15

341

P51511
KTPEVGPGPPPGPLS

KDM6B

636

O15054
GPGPPPGPLSKAPQP

KDM6B

641

O15054
PKGPPGPPGPSGAVV

COLEC12

576

Q5KU26
PGRAPEVGPSGPPLP

LRP3

671

O75074
APEPSQKPPGKPCPG

CFP

226

P27918
PPPAPAGTLLPGPSK

GGN

96

Q86UU5
EKPEAPAEPPGPGPG

OLIG1

71

Q8TAK6
PPPPPGGLPAKRGED

CRACDL

136

Q6NV74
SPPEGPPNPGPDGGK

CRACDL

356

Q6NV74
PTPPVLPDEEKGPPG

CRACDL

441

Q6NV74
PPPGGPPGALAVRPS

DTX1

236

Q86Y01
KKPPGTPPPSALPLG

GORASP1

211

Q9BQQ3
PPEPPPGPEVKGGSC

PPP1R37

646

O75864
PPPPDKLEGGGGPAP

PYGO2

6

Q9BRQ0
KLEGGGGPAPPPAPP

PYGO2

11

Q9BRQ0
GGPAPPPAPPSTGRK

PYGO2

16

Q9BRQ0
LSPSPGKGPPPAVAP

MYO15B

1141

Q96JP2
GPLGPLGCTSPPPAP

FAM189B

216

P81408
NVPSYPGPPGPPGPK

COL19A1

836

Q14993
DPSSGPPGPCHKLPP

AXIN1

426

O15169
PPPPLPPGAIAGAGS

FOXK1

56

P85037
PGPGVPPHPPGTKSA

AKNA

866

Q7Z591
PPLPPRNAGKGPTGP

ASAP1

791

Q9ULH1
PPKPGELPPKPQLGD

ASAP1

956

Q9ULH1
PGPDPGPPKTKHPDR

MAST4

2196

O15021
APPPPPPVEVKGEDG

DNAAF1

446

Q8NEP3
LPGPGAPTTEPTKPP

FOXS1

6

O43638
APKPKGPGEPDSPTP

KMT2A

1826

Q03164
PPGPPGPKVSVDEPG

COL7A1

2086

Q02388
PESKPGPVGPELPPG

BAG3

321

O95817
AGPGPSKGPPEPPPV

DHX37

16

Q8IY37
TGPDSPSPVPLPPGK

SAMD1

421

Q6SPF0
LPPGKPALPGADGTP

SAMD1

431

Q6SPF0
KPPLPAEKPAPGPGL

SLC38A10

651

Q9HBR0
AEKPAPGPGLPPEPR

SLC38A10

656

Q9HBR0
PGGEKPPPPPAEARE

CABLES2

66

Q9BTV7
PLAAPPPPGASAKGP

HS3ST4

16

Q9Y661
GPLAPPKSPEPSGPL

PTCHD3

46

Q3KNS1
SQGPPPTPGKPEGPP

PRB4

131

P10163
GPPLPPAAALRPPGK

INSM1

186

Q01101
PPPTALGFGPGKPPP

MED19

16

A0JLT2
KISPPPGPGPDPGPS

RUSC2

426

Q8N2Y8
ATKGPGPLGPGAPPP

RTN1

566

Q16799
PGPAPCTGGPKPLSP

STAP2

276

Q9UGK3
KPPPGPETNGEDPLP

TEDC2

51

Q7L2K0
PDGAPKASPPPPAGH

IRX1

326

P78414
APPGTPTPPPGGKDR

PIM2

11

Q9P1W9
DGSPIGPPSLLGPPP

PRR3

31

P79522
PPVPKVEPKGDGIGP

PRRC2A

611

P48634
DLEKLGGKSPPPPPP

KIAA1217

1036

Q5T5P2
GPGKPGLKFNGPPPP

SMN1

206

Q16637
EPLAKEKPGTPPGPP

SETD1B

441

Q9UPS6
PGGPPNPPGPSPKAL

WIZ

1096

O95785
PPPPAPASEPKGGLT

PRR12

1046

Q9ULL5
LAPGGPGPRPKPPAP

EXTL1

616

Q92935
KPPAPPSLPAGPPGV

SF3A2

216

Q15428
PKGEGAGPPPPLPPA

ATAD3B

11

Q5T9A4
AKGAKPEPAPAPPPP

CMTM2

6

Q8TAZ6
GKGPEPAKPPEPGKP

CMTM2

226

Q8TAZ6
VTTGKPPAPPQPGGP

CLASRP

351

Q8N2M8
QGPPPRPGKPEGSPS

PRB3

216

Q04118
PPGKPQGPPPQGDKS

PRB1

256

P04280
PPAKGEGGAPPLPPR

ZNF516

986

Q92618
EGGAPPLPPREPPSK

ZNF516

991

Q92618
PQAGEPPPPLAGDKP

ZNF48

436

Q96MX3
KGIPAALSPGPGPIP

TPRX1

86

Q8N7U7
PPPGKLGGAVPFAPP

nan

76

Q6ZSR9
KEKPPPPPPGGGKDL

SYNGAP1

791

Q96PV0
PGLRPVPGKPPGVDP

TLE4

341

Q04727
HGEPGPGPPPSGPKE

SP7

376

Q8TDD2
PRPPKEPGPPDKGGP

SCAF1

1291

Q9H7N4
EPGPPDKGGPGLPLP

SCAF1

1296

Q9H7N4
EGPPGPPSGPAPRKK

TOM1

466

O60784
PPAKAEASPEPGPGP

SH2B3

96

Q9UQQ2
PVPPLKGSPGCPLGP

VPS37D

221

Q86XT2
PGIPTPGSGLPPPRK

CAD

381

P27708
PPPPPLAPQKASGGG

SKOR2

836

Q2VWA4
SPPPPQPGRDKPGAG

MYO18B

1216

Q8IUG5
LGSPPGPKPGFAPPP

WASF2

306

Q9Y6W5
PPAEPEPIPKGSRPG

ZNF469

251

Q96JG9
PGLVPPISKPPPGFS

ZNF598

701

Q86UK7
GPKPNLVPGGVPDPP

SH2D3C

101

Q8N5H7
PGAPGETPAPKLPPG

ZNF142

86

P52746
GLPPTASALGPGPPP

VPS72

331

Q15906
PPLPGGPGIASPCPT

WNK2

1096

Q9Y3S1
KPTCGGGGEPEPPPP

ZNF367

41

Q7RTV3
QLAPPGTPAPPDGPK

RNF39

251

Q9H2S5
KADPFPPNGAPPLGP

ZC3H18

256

Q86VM9
GPPASPGKAQPPKPE

KIAA1522

541

Q9P206
PKGGLATPPPKGAPT

NACA

1136

E9PAV3
PPSPKGGLATPPPKG

NACA

1156

E9PAV3
PKGGPATPPPKGAPT

NACA

1251

E9PAV3
PPSPEKGPATPAPKG

NACA

1621

E9PAV3
PKPFPGGTGPPIKAE

MYRF

111

Q9Y2G1
IHGDPPGPGAKPPAP

MZF1

461

P28698
PGPGAKPPAPPGAPE

MZF1

466

P28698