Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprolactin receptor binding

CSH1 CSH2 CSHL1

1.04e-067633GO:0005148
GeneOntologyMolecularFunctiongrowth hormone receptor binding

CSH1 CSH2 CSHL1

3.54e-0610633GO:0005131
GeneOntologyMolecularFunctionhormone receptor binding

CSH1 CSH2 CSHL1

1.67e-0434633GO:0051427
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSP90AB4P TOR1A HSP90AB2P

2.72e-0440633GO:0140662
GeneOntologyMolecularFunctionco-SMAD binding

TRIM33 SMAD3

6.34e-0412632GO:0070410
GeneOntologyBiologicalProcesspositive regulation of steroid hormone biosynthetic process

CSH1 CSH2 CSHL1

6.89e-0613613GO:0090031
GeneOntologyBiologicalProcesspositive regulation of hormone biosynthetic process

CSH1 CSH2 CSHL1

2.31e-0519613GO:0046886
GeneOntologyBiologicalProcessregulation of hormone metabolic process

CSH1 CSH2 CSHL1 PRMT3

2.61e-0558614GO:0032350
GeneOntologyBiologicalProcessregulation of steroid hormone biosynthetic process

CSH1 CSH2 CSHL1

4.77e-0524613GO:0090030
GeneOntologyBiologicalProcesspre-B cell allelic exclusion

RAG1 ATM

5.14e-054612GO:0002331
GeneOntologyBiologicalProcessgrowth hormone receptor signaling pathway

CSH1 CSH2 CSHL1

6.10e-0526613GO:0060396
GeneOntologyBiologicalProcesspositive regulation of hormone metabolic process

CSH1 CSH2 CSHL1

6.10e-0526613GO:0032352
GeneOntologyBiologicalProcesscellular response to growth hormone stimulus

CSH1 CSH2 CSHL1

6.84e-0527613GO:0071378
GeneOntologyBiologicalProcessmulticellular organism growth

CSH1 CSH2 CSHL1 PLEKHA1 ATM SLC12A5

9.29e-05249616GO:0035264
GeneOntologyBiologicalProcesscellular response to heat

NF1 HSP90AB4P HSP90AB2P ATM

9.71e-0581614GO:0034605
GeneOntologyBiologicalProcessregulation of hormone biosynthetic process

CSH1 CSH2 CSHL1

1.64e-0436613GO:0046885
GeneOntologyBiologicalProcesspositive regulation of steroid biosynthetic process

CSH1 CSH2 CSHL1

1.93e-0438613GO:0010893
GeneOntologyBiologicalProcesshormone metabolic process

CYP2C9 CSH1 CSH2 CSHL1 PLEKHA1 PRMT3

1.97e-04286616GO:0042445
GeneOntologyBiologicalProcesschiasma assembly

MSH5 TEX11

2.38e-048612GO:0051026
GeneOntologyBiologicalProcessresponse to growth hormone

CSH1 CSH2 CSHL1

2.42e-0441613GO:0060416
GeneOntologyBiologicalProcessneuroblast proliferation

NF1 CSH1 CSH2 CSHL1

2.55e-04104614GO:0007405
GeneOntologyBiologicalProcesspositive regulation of steroid metabolic process

CSH1 CSH2 CSHL1

2.60e-0442613GO:0045940
GeneOntologyBiologicalProcessregulation of response to nutrient levels

CSH1 CSH2 CSHL1

3.41e-0446613GO:0032107
GeneOntologyBiologicalProcesscytokinesis

INCENP CECR2 KIF4B FSD1 BIN3

3.42e-04204615GO:0000910
GeneOntologyBiologicalProcesspositive regulation of multicellular organism growth

CSH1 CSH2 CSHL1

3.64e-0447613GO:0040018
GeneOntologyBiologicalProcessresponse to temperature stimulus

NF1 HSP90AB4P HSP90AB2P ATM SLC12A5

3.74e-04208615GO:0009266
GeneOntologyBiologicalProcesschromosome segregation

NEK6 INCENP KIF4B MSH5 ATM TEX11 TUBGCP5

4.32e-04465617GO:0007059
GeneOntologyBiologicalProcessresponse to heat

NF1 HSP90AB4P HSP90AB2P ATM

4.54e-04121614GO:0009408
GeneOntologyBiologicalProcessmitotic spindle midzone assembly

INCENP KIF4B

4.65e-0411612GO:0051256
GeneOntologyBiologicalProcessspindle organization

NEK6 INCENP KIF4B FSD1 TUBGCP5

5.24e-04224615GO:0007051
GeneOntologyBiologicalProcesscytoskeleton-dependent cytokinesis

INCENP CECR2 KIF4B BIN3

5.45e-04127614GO:0061640
GeneOntologyBiologicalProcessmitotic spindle elongation

INCENP KIF4B

5.57e-0412612GO:0000022
GeneOntologyBiologicalProcessnuclear chromosome segregation

NEK6 INCENP KIF4B MSH5 ATM TEX11

6.33e-04356616GO:0098813
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle endocytosis

ABCA13 TOR1A

6.57e-0413612GO:1900244
GeneOntologyBiologicalProcessresponse to food

CSH1 CSH2 CSHL1

6.76e-0458613GO:0032094
GeneOntologyBiologicalProcesspositive regulation of receptor signaling pathway via JAK-STAT

CSH1 CSH2 CSHL1

6.76e-0458613GO:0046427
GeneOntologyBiologicalProcessprotein stabilization

HSP90AB4P PIH1D2 HSP90AB2P SMAD3 NAA16

7.57e-04243615GO:0050821
GeneOntologyBiologicalProcessspindle midzone assembly

INCENP KIF4B

7.65e-0414612GO:0051255
GeneOntologyBiologicalProcessspindle elongation

INCENP KIF4B

7.65e-0414612GO:0051231
GeneOntologyBiologicalProcesspositive regulation of D-glucose transmembrane transport

CSH1 CSH2 CSHL1

8.61e-0463613GO:0010828
GeneOntologyBiologicalProcesspre-B cell differentiation

RAG1 ATM

8.81e-0415612GO:0002329
GeneOntologyBiologicalProcesspositive regulation of receptor signaling pathway via STAT

CSH1 CSH2 CSHL1

9.44e-0465613GO:1904894
GeneOntologyBiologicalProcessfructose metabolic process

PFKFB3 ALDOB

1.01e-0316612GO:0006000
GeneOntologyBiologicalProcessreciprocal meiotic recombination

MSH5 ATM TEX11

1.03e-0367613GO:0007131
GeneOntologyBiologicalProcessreciprocal homologous recombination

MSH5 ATM TEX11

1.03e-0367613GO:0140527
GeneOntologyBiologicalProcessmitotic spindle organization

NEK6 INCENP KIF4B FSD1

1.04e-03151614GO:0007052
GeneOntologyCellularComponentgrowth hormone receptor complex

CSH1 CSH2 CSHL1

5.18e-076633GO:0070195
GeneOntologyCellularComponentcentral element

INCENP TEX11

2.47e-048632GO:0000801
GeneOntologyCellularComponentsynaptonemal complex

INCENP MSH5 TEX11

3.61e-0446633GO:0000795
GeneOntologyCellularComponentsynaptonemal structure

INCENP MSH5 TEX11

3.61e-0446633GO:0099086
MousePhenodecreased pituitary gland weight

CSH1 CSH2 CSHL1

2.24e-068493MP:0008938
MousePhenoabsent somatotrophs

CSH1 CSH2 CSHL1

3.35e-069493MP:0008330
MousePhenoabsent lactotrophs

CSH1 CSH2 CSHL1

3.35e-069493MP:0008333
MousePhenoincreased circulating ghrelin level

CSH1 CSH2 CSHL1

8.71e-0612493MP:0011612
MousePhenoabnormal pituitary gland weight

CSH1 CSH2 CSHL1

8.71e-0612493MP:0008937
MousePhenoabnormal circulating ghrelin level

CSH1 CSH2 CSHL1

1.79e-0515493MP:0011611
MousePhenodecreased lactotroph cell number

CSH1 CSH2 CSHL1

2.66e-0517493MP:0008332
MousePhenoabnormal lactotroph morphology

CSH1 CSH2 CSHL1

3.77e-0519493MP:0008323
MousePhenodecreased somatotroph cell number

CSH1 CSH2 CSHL1

5.15e-0521493MP:0008329
MousePhenosmall adenohypophysis

CSH1 CSH2 CSHL1

6.82e-0523493MP:0008321
MousePhenoabnormal somatotroph morphology

CSH1 CSH2 CSHL1

7.78e-0524493MP:0008322
MousePhenodecreased kidney weight

CSH1 CSH2 CSHL1 SMAD3

8.18e-0566494MP:0003918
MousePhenoabnormal kidney weight

CSH1 CSH2 CSHL1 PRAMEF22 LYST SMAD3

8.28e-05208496MP:0002707
MousePhenoectopic Purkinje cell

TOR1A ATM LYST

9.94e-0526493MP:0000885
MousePhenodelayed vaginal opening

CSH1 CSH2 CSHL1

1.25e-0428493MP:0002636
MousePhenosmall pituitary gland

CSH1 CSH2 CSHL1

1.54e-0430493MP:0005361
MousePhenoabnormal timing of vaginal opening

CSH1 CSH2 CSHL1

1.70e-0431493MP:0020150
MousePhenodecreased bone mineral density

CSH1 CSH2 CSHL1 PRMT3 MSH5 PFKFB3 ALDOB SMAD3

2.25e-04476498MP:0000063
MousePhenodecreased body length

MAF1 CYP2C9 PLVAP CSH1 CSH2 CSHL1 PRMT3 ALDOB

2.52e-04484498MP:0001258
MousePhenopale liver

FLI1 SIN3B NF1 ALDOB

2.97e-0492494MP:0000603
MousePhenoincreased leukemia incidence

FLI1 NF1 ATM

3.38e-0439493MP:0002026
MousePhenoabnormal pituitary gland size

CSH1 CSH2 CSHL1

4.22e-0442493MP:0008936
MousePhenoovary degeneration

MSH5 ATM

4.27e-049492MP:0013236
MousePhenoincreased brown adipose tissue amount

CSH1 CSH2 CSHL1

4.53e-0443493MP:0000005
MousePhenoincreased tumor incidence

RAG1 FLI1 NF1 MSH5 ATM BIN3 LYST SMAD3

4.63e-04530498MP:0002020
MousePhenosmall spleen

RAG1 CSH1 CSH2 CSHL1 ATM SMAD3 SLC12A5

5.73e-04416497MP:0000692
MousePhenoabnormal body length

MAF1 CYP2C9 PLVAP CSH1 CSH2 CSHL1 PRMT3 ALDOB

5.92e-04550498MP:0001256
MousePhenoectopic neuron

TOR1A ATM LYST

6.27e-0448493MP:0011723
MousePhenodelayed sexual maturation

CSH1 CSH2 CSHL1

6.66e-0449493MP:0001938
MousePhenoabnormal bone structure

CYP2C9 CSH1 CSH2 CSHL1 PLEKHA1 PRMT3 MSH5 SSH2 PFKFB3 ALDOB TRIP11 SMAD3 SLC12A5

7.01e-0413794913MP:0003795
MousePhenoincreased white adipose tissue amount

CSH1 CSH2 CSHL1

7.93e-0452493MP:0000008
MousePhenoabnormal white adipose tissue morphology

MAF1 CSH1 CSH2 CSHL1 PRMT3 ATM

8.52e-04321496MP:0002970
DomainSomatotropin

ZFHX4 CSH1 CSH2 CSHL1

3.58e-097614IPR001400
DomainSOMATOTROPIN_2

CSH1 CSH2 CSHL1

6.58e-076613PS00338
DomainHormone_1

CSH1 CSH2 CSHL1

6.58e-076613PF00103
DomainSOMATOTROPIN_1

CSH1 CSH2 CSHL1

6.58e-076613PS00266
DomainSomatotropin_CS

CSH1 CSHL1

1.04e-045612IPR018116
DomainARM-type_fold

PPP2R5D NF1 UPF2 ELMO2 MROH2A ATM LYST

1.15e-04339617IPR016024
Domain4_helix_cytokine_core

CSH1 CSH2 CSHL1

6.17e-0451613IPR012351
DomainBbox_C

TRIM33 FSD1

1.07e-0315612IPR003649
DomainBBC

TRIM33 FSD1

1.07e-0315612SM00502
DomainBAR

SNX30 BIN3

1.07e-0315612PF03114
DomainBAR_dom

SNX30 BIN3

1.22e-0316612IPR004148
Domain4_helix_cytokine-like_core

CSH1 CSH2 CSHL1

1.82e-0374613IPR009079
Domain-

ASAP2 BIN3

4.30e-03306121.20.1270.60
DomainAH/BAR-dom

ASAP2 BIN3

4.30e-0330612IPR027267
DomainBROMODOMAIN_1

TRIM33 CECR2

6.49e-0337612PS00633
DomainBromodomain

TRIM33 CECR2

6.84e-0338612PF00439
DomainBROMODOMAIN_2

TRIM33 CECR2

7.93e-0341612PS50014
DomainBROMO

TRIM33 CECR2

8.31e-0342612SM00297
DomainBromodomain

TRIM33 CECR2

8.31e-0342612IPR001487
Domain-

TRIM33 CECR2

8.31e-03426121.20.920.10
PathwayREACTOME_PROLACTIN_RECEPTOR_SIGNALING

CSH1 CSH2 CSHL1

9.09e-0613463MM14516
PathwayREACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING

CSH1 CSH2 CSHL1

1.77e-0516463MM15710
PathwayBIOCARTA_LONGEVITY_PATHWAY

CSH1 CSH2 CSHL1

3.04e-0519463MM1513
PathwayREACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN

CSH1 CSH2 CSHL1

3.57e-0520463MM15070
PathwayBIOCARTA_AKT_PATHWAY

CSH1 CSH2 CSHL1

8.02e-0526463MM1345
PathwayBIOCARTA_TFF_PATHWAY

CSH1 CSH2 CSHL1

1.12e-0429463MM1522
PathwayBIOCARTA_GH_PATHWAY

CSH1 CSH2 CSHL1

1.66e-0433463MM1404
PathwayWP_OVARIAN_INFERTILITY

MSH5 ATM SMAD3

1.98e-0435463MM15948
PathwayWP_OVARIAN_INFERTILITY

MSH5 ATM SMAD3

2.74e-0439463M39458
PathwayREACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM

PPP2R5D PFKFB3

6.73e-0412462M27950
Pubmed

Localization of the growth hormone gene to the distal half of mouse chromosome 11.

CSH1 CSH2 CSHL1 EVI2A

1.22e-0996342286379
Pubmed

The human growth hormone gene locus: structure, evolution, and allelic variations.

CSH1 CSH2 CSHL1

5.66e-0936333030680
Pubmed

Physical and linkage mapping of human chromosome 17 loci to dog chromosomes 9 and 5.

NF1 CSH1 CSH2 CSHL1

1.75e-08166349177778
Pubmed

Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster.

CSH1 CSH2 CSHL1

2.26e-0846331378436
Pubmed

Central growth hormone action regulates metabolism during pregnancy.

CSH1 CSH2 CSHL1

5.65e-08563331479305
Pubmed

Molecular evolution of growth hormone and receptor in the guinea-pig, a mammal unresponsive to growth hormone.

CSH1 CSH2 CSHL1

5.65e-08563310767558
Pubmed

Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference.

CSH1 CSH2 CSHL1

5.65e-08563318006625
Pubmed

Growth hormone prevents the development of autoimmune diabetes.

CSH1 CSH2 CSHL1

5.65e-08563324218587
Pubmed

Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype.

CSH1 CSH2 CSHL1

5.65e-0856339546108
Pubmed

Transgene transmission to progeny by oMt1a-oGH transgenic mice.

CSH1 CSH2 CSHL1

5.65e-08563316201410
Pubmed

Genes that prolong life: relationships of growth hormone and growth to aging and life span.

CSH1 CSH2 CSHL1

5.65e-08563311487592
Pubmed

Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice.

CSH1 CSH2 CSHL1

5.65e-08563311318985
Pubmed

Identification of the glomerular podocyte as a target for growth hormone action.

CSH1 CSH2 CSHL1

5.65e-08563317272398
Pubmed

Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis.

CSH1 CSH2 CSHL1

5.65e-08563320707609
Pubmed

Induction of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice.

CSH1 CSH2 CSHL1

5.65e-0856331874564
Pubmed

Growth Hormone Deficiency and Excess Alter the Gut Microbiome in Adult Male Mice.

CSH1 CSH2 CSHL1

5.65e-08563332100023
Pubmed

Transgenic mice expressing bovine GH develop arthritic disorder and self-antibodies.

CSH1 CSH2 CSHL1

5.65e-08563310810296
Pubmed

Somatotropin transgenic mice have reduced jejunal active glucose transport rates.

CSH1 CSH2 CSHL1

5.65e-0856337965203
Pubmed

Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.

CSH1 CSH2 CSHL1

5.65e-08563317347312
Pubmed

Pleiotropic effects of growth hormone signaling in aging.

CSH1 CSH2 CSHL1

5.65e-08563321852148
Pubmed

Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.

CSH1 CSH2 CSHL1

5.65e-08563312175649
Pubmed

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation.

CSH1 CSH2 CSHL1

5.65e-08563315070902
Pubmed

A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity.

CSH1 CSH2 CSHL1

5.65e-08563314726450
Pubmed

UV photodegradation of murine growth hormone: chemical analysis and immunogenicity consequences.

CSH1 CSH2 CSHL1

5.65e-08563324758742
Pubmed

Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes.

CSH1 CSH2 CSHL1

5.65e-08563310076541
Pubmed

Overgrowth of skin in growth hormone transgenic mice depends on the presence of male gonads.

CSH1 CSH2 CSHL1

5.65e-08563310594738
Pubmed

Hypoxia and cytoplasmic alkalinization upregulate growth hormone expression in lymphocytes.

CSH1 CSH2 CSHL1

5.65e-08563323639351
Pubmed

Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood.

CSH1 CSH2 CSHL1

5.65e-08563321098290
Pubmed

Age-related changes in body composition of bovine growth hormone transgenic mice.

CSH1 CSH2 CSHL1

5.65e-08563318948397
Pubmed

Heterogeneous growth hormone (GH) gene mutations in familial GH deficiency.

CSH1 CSH2 CSHL1

5.65e-0856338496314
Pubmed

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.

CSH1 CSH2 CSHL1

5.65e-08563321045135
Pubmed

Analysis of gender difference of cardiac risk biomarkers using hGH-transgenic mice.

CSH1 CSH2 CSHL1

5.65e-08563316508206
Pubmed

Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.

CSH1 CSH2 CSHL1

5.65e-08563315616010
Pubmed

Nitric oxide stimulates embryonic somatotroph differentiation and growth hormone mRNA and protein expression through a cyclic guanosine monophosphate-independent mechanism.

CSH1 CSH2 CSHL1

5.65e-08563319019400
Pubmed

The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH?

CSH1 CSH2 CSHL1

5.65e-08563332556100
Pubmed

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice.

CSH1 CSH2 CSHL1

5.65e-0856331525063
Pubmed

Obesity and elevated plasma leptin concentration in oMT1A-o growth hormone transgenic mice.

CSH1 CSH2 CSHL1

5.65e-08563311346667
Pubmed

Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice.

CSH1 CSH2 CSHL1

5.65e-08563312010633
Pubmed

Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.

CSH1 CSH2 CSHL1

5.65e-08563317626886
Pubmed

Regulation of rapid signal transducer and activator of transcription-5 phosphorylation in the resting cells of the growth plate and in the liver by growth hormone and feeding.

CSH1 CSH2 CSHL1

5.65e-08563319359380
Pubmed

Growth hormone stimulates the selective trafficking of thymic CD4+CD8- emigrants to peripheral lymphoid organs.

CSH1 CSH2 CSHL1

5.65e-08563315316240
Pubmed

Involvement of insulin-like growth factor-1 in the effect of caloric restriction: regulation of plasma adiponectin and leptin.

CSH1 CSH2 CSHL1

5.65e-08563317301034
Pubmed

Growth hormone action in the developing neural retina: a proteomic analysis.

CSH1 CSH2 CSHL1

5.65e-08563318203262
Pubmed

Assignment of the porcine growth hormone gene to chromosome 12.

CSH1 CSH2 CSHL1

5.65e-0856332249485
Pubmed

Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARgamma pathway.

CSH1 CSH2 CSHL1

5.65e-08563317242167
Pubmed

A single injection of double-stranded adeno-associated viral vector expressing GH normalizes growth in GH-deficient mice.

CSH1 CSH2 CSHL1

5.65e-08563318180319
Pubmed

Cloning and characterisation of the GH gene from the common dolphin (Delphinus delphis).

CSH1 CSH2 CSHL1

5.65e-08563312225773
Pubmed

The related genes encoding growth hormone and prolactin have been dispersed to chromosomes 10 and 17 in the rat.

CSH1 CSH2 CSHL1

5.65e-0856333780533
Pubmed

High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice.

CSH1 CSH2 CSHL1

5.65e-08563310395045
Pubmed

Effect of genetic background on growth of mice hemizygous for wild-type or dwarf mutated bovine growth hormone transgenes.

CSH1 CSH2 CSHL1

5.65e-08563324190208
Pubmed

Brief report: short stature caused by a mutant growth hormone.

CSH1 CSH2 CSHL1

5.65e-0856338552145
Pubmed

Promotion of Joint Degeneration and Chondrocyte Metabolic Dysfunction by Excessive Growth Hormone in Mice.

CSH1 CSH2 CSHL1

5.65e-08563336762426
Pubmed

High molecular weight isoforms of growth hormone in cells of the immune system.

CSH1 CSH2 CSHL1

5.65e-08563321741628
Pubmed

Structure of the growth hormone-encoding gene and its promoter in mice.

CSH1 CSH2 CSHL1

5.65e-0856338647448
Pubmed

Thiol-Disulfide Exchange in Human Growth Hormone.

CSH1 CSH2 CSHL1

5.65e-08563326887678
Pubmed

The role of growth hormone in fetal mouse reproductive tract differentiation.

CSH1 CSH2 CSHL1

5.65e-0856338756530
Pubmed

GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity.

CSH1 CSH2 CSHL1

5.65e-08563331099824
Pubmed

Hot spots for growth hormone gene deletions in homologous regions outside of Alu repeats.

CSH1 CSH2 CSHL1

5.65e-0856331980158
Pubmed

Vitamin D3 cannot revert desensitization of growth hormone (GH)-induced STAT5-signaling in GH-overexpressing mice non-calcemic tissues.

CSH1 CSH2 CSHL1

5.65e-08563317881271
Pubmed

Neural growth hormone implicated in body weight sex differences.

CSH1 CSH2 CSHL1

5.65e-08563323861378
Pubmed

Growth hormone increases low-density lipoprotein receptor and HMG-CoA reductase mRNA expression in mesangial cells.

CSH1 CSH2 CSHL1

5.65e-08563312759574
Pubmed

Growth hormone production and action in N1E-115 neuroblastoma cells.

CSH1 CSH2 CSHL1

5.65e-08563319301152
Pubmed

Adipocyte insensitivity to insulin in growth hormone-transgenic mice.

CSH1 CSH2 CSHL1

5.65e-08563311350075
Pubmed

Transgenic mice overexpressing growth hormone (GH) have reduced or increased cardiac apoptosis through activation of multiple GH-dependent or -independent cell death pathways.

CSH1 CSH2 CSHL1

5.65e-08563318617616
Pubmed

Growth hormone and fertility in oMt1a-oGH transgenic mice.

CSH1 CSH2 CSHL1

5.65e-08563311570960
Pubmed

Promoter shuffling has occurred during the evolution of the vertebrate growth hormone gene.

CSH1 CSH2 CSHL1

5.65e-08563310974531
Pubmed

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone.

CSH1 CSH2 CSHL1

5.65e-08563323428905
Pubmed

Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH.

CSH1 CSH2 CSHL1

5.65e-08563317761891
Pubmed

Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor.

CSH1 CSH2 CSHL1

1.13e-07663312399427
Pubmed

GH modulates hepatic epidermal growth factor signaling in the mouse.

CSH1 CSH2 CSHL1

1.13e-07663320032199
Pubmed

Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.

CSH1 CSH2 CSHL1

1.13e-07663311316754
Pubmed

The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female mice.

CSH1 CSH2 CSHL1

1.13e-07663323150490
Pubmed

Nucleotide sequence of mouse prolactin and growth hormone mRNAs and expression of these mRNAs during pregnancy.

CSH1 CSH2 CSHL1

1.13e-0766332991252
Pubmed

Third party data gene data set of eutherian growth hormone genes.

CSH1 CSH2 CSHL1

1.13e-07663326697363
Pubmed

Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse.

CSH1 CSH2 CSHL1

1.13e-07663315985453
Pubmed

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.

CSH1 CSH2 CSHL1

1.13e-07663320863500
Pubmed

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.

CSH1 CSH2 CSHL1

1.13e-07663312208853
Pubmed

Involvement of growth hormone as a regulating factor in sex differences of mouse hepatic aldehyde oxidase.

CSH1 CSH2 CSHL1

1.13e-0766339175714
Pubmed

Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse.

CSH1 CSH2 CSHL1

1.13e-07663316141391
Pubmed

Sex differences in thrombosis in mice are mediated by sex-specific growth hormone secretion patterns.

CSH1 CSH2 CSHL1

1.13e-07663318618017
Pubmed

Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes.

CSH1 CSH2 CSHL1

1.13e-07663314759511
Pubmed

Administration of human insulin-like growth factor-binding protein-1 increases circulating levels of growth hormone in mice.

CSH1 CSH2 CSHL1

1.13e-07663315166120
Pubmed

Osteocalcin induces growth hormone/insulin-like growth factor-1 system by promoting testosterone synthesis in male mice.

CSH1 CSH2 CSHL1

1.13e-07663324691732
Pubmed

CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment.

CSH1 CSH2 CSHL1

1.13e-07663338951485
Pubmed

Evidence that growth hormone exerts a feedback effect on stomach ghrelin production and secretion.

CSH1 CSH2 CSHL1

1.13e-07663314530511
Pubmed

Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes.

CSH1 CSH2 CSHL1

1.13e-07663321849508
Pubmed

Stimulation of endogenous pulsatile growth hormone secretion by activation of growth hormone secretagogue receptor reduces the fat accumulation and improves the insulin sensitivity in obese mice.

CSH1 CSH2 CSHL1

1.13e-07663333368660
Pubmed

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice.

CSH1 CSH2 CSHL1

1.13e-07663314702113
Pubmed

Systemic over-secretion of growth hormone in transgenic mice results in a specific pattern of skeletal modeling and adaptation.

CSH1 CSH2 CSHL1

1.13e-0766339556071
Pubmed

Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy.

CSH1 CSH2 CSHL1

1.13e-0766338990189
Pubmed

Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice.

CSH1 CSH2 CSHL1

1.13e-07663312933669
Pubmed

Insulin-like growth factor 1 mediates negative feedback to somatotroph GH expression via POU1F1/CREB binding protein interactions.

CSH1 CSH2 CSHL1

1.13e-07663322890843
Pubmed

Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice.

CSH1 CSH2 CSHL1

1.13e-07663315138153
Pubmed

Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae.

CSH1 CSH2 CSHL1

1.13e-07663330333823
Pubmed

GH/STAT5 signaling during the growth period in livers of mice overexpressing GH.

CSH1 CSH2 CSHL1

1.13e-07663325691498
Pubmed

The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice.

CSH1 CSH2 CSHL1

1.13e-07663323349524
Pubmed

Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.

CSH1 CSH2 CSHL1

1.13e-07663326762506
Pubmed

Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice.

CSH1 CSH2 CSHL1

1.13e-07663325811804
Pubmed

Growth hormone protects against ovariectomy-induced bone loss in states of low circulating insulin-like growth factor (IGF-1).

CSH1 CSH2 CSHL1

1.13e-07663319619004
Pubmed

Functional modification of pituitary somatotropes in the aromatase knockout mouse and the effect of estrogen replacement.

CSH1 CSH2 CSHL1

1.13e-07663314563698
InteractionCSH2 interactions

CSH1 CSH2 CSHL1 SMAD3

1.08e-0715624int:CSH2
InteractionCSH1 interactions

CSH1 CSH2 CSHL1 SMAD3

2.41e-0718624int:CSH1
InteractionCSHL1 interactions

CSH1 CSH2 CSHL1

9.62e-077623int:CSHL1
Cytoband17q24.2

CSH1 CSH2 CSHL1

9.74e-063063317q24.2
Cytoband17q11.2

NF1 EVI2A SSH2

4.79e-0411063317q11.2
CytobandEnsembl 112 genes in cytogenetic band chr17q23

CSH1 CSH2 CSHL1

6.17e-04120633chr17q23
CytobandEnsembl 112 genes in cytogenetic band chr17q11

NF1 EVI2A SSH2

1.71e-03171633chr17q11
GeneFamilyGrowth hormone family

CSH1 CSH2 CSHL1

1.71e-0763831175
CoexpressionAtlasBM Top 100 - pituitary gland

CSH1 CSH2 CSHL1 PEG10

5.94e-0576594BM Top 100 - pituitary gland
CoexpressionAtlaskidney_e10.5_UretericTrunk_HoxB7_top-relative-expression-ranked_200

FLI1 CECR2 PLEKHA1 SSH2 KLHL4

6.25e-05151595gudmap_kidney_e10.5_UretericTrunk_HoxB7_200
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_500

FLI1 PEG10 KLHL4

6.35e-0528593gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_500
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_1000

FLI1 ASAP2 PLVAP NEK6 PEG10 PLEKHA1 SSH2 PFKFB3 FGD6 KLHL4

7.65e-058175910gudmap_dev gonad_e11.5_F_ReproVasc_Flk_1000
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TRIM33 GLOD5 ATM SERINC5 TEX11 TUBGCP5

3.20e-071936369337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 ZFHX4 MROH2A UNC13C MSH5

1.90e-061446351d05aa08603cba28c0c6511767e434c1f592a3aa
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 ZFHX4 MROH2A UNC13C MSH5

1.90e-06144635d3f6f5da56794367ee3776bfd3a9dcf893efe0f0
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

FLI1 PLVAP PLEKHA1 ALDOB KLHL4

5.50e-06179635d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 MIA2 CECR2 TRIP11 LYST

5.96e-06182635f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 PLVAP CECR2 SERINC5 FGD6

6.12e-06183635bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 PLVAP CECR2 SERINC5 FGD6

6.12e-061836354c325ee6da070513097a11445ec95b0415ffd8a2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 ABCA13 MROH2A UNC13C TEX11

6.28e-06184635ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 ABCA13 MROH2A UNC13C TEX11

6.28e-061846352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 ABCA13 MROH2A UNC13C TEX11

6.28e-061846352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 MIA2 CECR2 TRIP11 LYST

6.45e-061856357adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GLOD5 ATM SERINC5 TEX11 TUBGCP5

8.75e-0619763557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellSevere-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PLEKHA1 FSD1 SERINC5 LYST

6.55e-0515363444572f87d403e314050ab935d2cd676c33d9c287
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 PLVAP INCENP KIF4B

6.89e-05155634969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PLEKHA1 FSD1 SERINC5 LYST

7.24e-05157634a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCellcellseq2-Epithelial-Epithelial_Airway-Secretory/RAS|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RAG1 CYP2C9 INCENP NELFA

9.85e-05170634b62f7184e78e9672ea88e361654f604f9df2dc5f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 PLEKHA1 SERINC5 PFKFB3

9.85e-051706345d5f208682be21ed58320f5fc083a7898f8712da
ToppCellcellseq2-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RAG1 CYP2C9 INCENP NELFA

9.85e-0517063400fe77bca9c28762212c498f9c49e14cb1492cca
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 CECR2 MROH2A MSH5

1.08e-041746344cdf2eedc28d88d18241ee390092426fdf849e79
ToppCellImmune_cells-pro-B|World / Lineage and Cell class

RAG1 CECR2 MROH2A MSH5

1.08e-04174634e173adbf5789dfa20f3cbc668efde5f0992ac219
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 CECR2 MROH2A MSH5

1.08e-04174634268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 CECR2 MROH2A MSH5

1.13e-0417663429cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 PLVAP MROH2A MSH5

1.13e-0417663488ca2f83d8301633232735f39b0683efe49d0b86
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 PLVAP MROH2A MSH5

1.13e-041766347292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 CECR2 MROH2A MSH5

1.13e-0417663401774a86d7d92f31a056b753f9844f923038003e
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PEG10 PLEKHA1 GBP2 FSD1

1.23e-0418063427672ac6a02172a31851f18decb9acffa8f5a703
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX4 UNC13C SERINC5 PFKFB3

1.23e-0418063449829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCellImmune_cells-large_pre-B.|World / Lineage and Cell class

RAG1 FSIP1 CECR2 MROH2A

1.31e-0418363481b5ed6ed661d2d6a9b807fefd2f0d59bd4ea77e
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 PLVAP GBP2 KLHL4

1.34e-04184634fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 PLVAP GBP2 KLHL4

1.34e-041846341d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLI1 PLVAP GBP2 KLHL4

1.34e-04184634ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 PLVAP GBP2 KLHL4

1.34e-0418463476caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLI1 PLVAP GBP2 KLHL4

1.34e-041846341fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLI1 PLVAP GBP2 KLHL4

1.34e-041846342467207aaea307873ab286f89cfc7668a227a694
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 INCENP CECR2 SERINC5

1.39e-04186634ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 INCENP CECR2 SERINC5

1.39e-041866343993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLI1 PLVAP PFKFB3 KLHL4

1.45e-041886346ab5ce8569f896a0fe7a76b8b4a83661e5499b8c
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLI1 PLVAP PFKFB3 KLHL4

1.45e-0418863420072a2a3f9ecbe727c850629f19420cf60e4bc5
ToppCellfacs-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLI1 PLVAP PFKFB3 KLHL4

1.45e-04188634dd817059e1b4225e84733559f7839cc973b7dfd6
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 PLVAP PFKFB3 KLHL4

1.48e-04189634476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 PLVAP PFKFB3 KLHL4

1.48e-041896343fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCellfacs-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 PLVAP PFKFB3 KLHL4

1.48e-04189634e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 PLVAP PFKFB3 KLHL4

1.48e-04189634d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCellfacs-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 PLVAP PFKFB3 KLHL4

1.48e-041896345559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCellfacs-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 PLVAP PFKFB3 KLHL4

1.48e-04189634f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCellCOVID-19-kidney-NK|kidney / Disease (COVID-19 only), tissue and cell type

FLI1 EVI2A ATM LYST

1.51e-04190634e3ca3c9fb9e27670a5dd128dd6564ff98a57159e
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PEG10 PLEKHA1 GBP2 FSD1

1.51e-0419063467fa7472ec534179087963177351552cc3c335eb
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PEG10 PLEKHA1 GBP2 FSD1

1.51e-04190634094efcde2b037ae509298abb8b2b1d52f9c86a45
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

FLI1 PLVAP PLEKHA1 KLHL4

1.54e-0419163444c596984c6196f6014e0e405dbe5560841e54ff
ToppCellE16.5-samps-Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

FLI1 PLVAP PLEKHA1 KLHL4

1.54e-04191634e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCellCD8+_Memory_T_cell-CV-0|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

PLEKHA1 ATM LYST SMAD3

1.60e-04193634995781d87a919c0380750878bafe584342bb83ad
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ATM SERINC5 TRIP11 NAA16

1.67e-04195634d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP2 EVI2A PFKFB3 LYST

1.70e-04196634fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP2 EVI2A PFKFB3 LYST

1.70e-04196634526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GBP2 EVI2A PFKFB3 LYST

1.74e-041976341acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP2 EVI2A PFKFB3 LYST

1.74e-041976343cd1c816bc7a57278b2ef615b69545356ab8f522
ToppCelllymphoid-T_cell|lymphoid / Lineage, cell class and subclass

EVI2A ATM SERINC5 SSH2

1.77e-0419863441573038b34803f664a7cb5a7d05b8afdff55b58
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLI1 ASAP2 PLVAP NF1

1.84e-042006342d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal|GW13 / Sample Type, Dataset, Time_group, and Cell type.

MIA2 SERINC5 TUBGCP5

2.38e-04856333f33e897eb030043905a6a1a83377cd601652958
Drug5-phenylhydantoin

CYP2C9 CSH2 CSHL1

5.66e-0613633CID000001002
Drug6-fluorocholesterol

ATM LYST

7.54e-062632CID000135206
Drug25-fluorocholesterol

ATM LYST

7.54e-062632CID006454807
DrugSureCN5628906

NF1 CSH2 CSHL1 EVI2A

1.52e-0554634CID010476254
Drug1,1-dimethylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A

ELMO2 PLEKHA1 IREB2 FSD1 PRMT3 BIN3

1.86e-0519963661_DN
Drugbeta-carene

CSH2 CSHL1

2.26e-053632CID000011129
Diseaseisolated growth hormone deficiency type II (implicated_via_orthology)

CSH1 CSH2 CSHL1

7.97e-085603DOID:0060872 (implicated_via_orthology)
Diseaseisolated growth hormone deficiency (implicated_via_orthology)

CSH1 CSH2 CSHL1

2.78e-077603DOID:0060870 (implicated_via_orthology)
Diseasecongenital hypothyroidism (biomarker_via_orthology)

CSH1 CSH2 CSHL1

2.86e-0614603DOID:0050328 (biomarker_via_orthology)
Diseaseosteoporosis (biomarker_via_orthology)

CSH1 CSH2 CSHL1

1.20e-0522603DOID:11476 (biomarker_via_orthology)
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

CSH1 CSH2 CSHL1

6.93e-0539603DOID:9744 (implicated_via_orthology)
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

CSH1 CSH2 CSHL1 ALDOB

2.32e-04147604DOID:9352 (biomarker_via_orthology)
DiseasePROSTATE CANCER, HEREDITARY, 1

INCENP TOR1A ATM

2.52e-0460603C4722327
Diseasemonocyte count

FLI1 PLVAP NF1 GALNT1 NEK6 CECR2 TADA2B ATM SSH2 LYST

3.04e-0413206010EFO_0005091
DiseaseProstate cancer, familial

INCENP TOR1A ATM

3.81e-0469603C2931456
Diseaseposterior thigh muscle volume

CSH1 CSHL1

4.20e-0415602EFO_0020931
Diseaserhinitis

NEK6 SMAD3

5.42e-0417602EFO_0008521
Diseasemonocyte percentage of leukocytes

FLI1 PLVAP NF1 NEK6 CECR2 TADA2B SSH2

6.88e-04731607EFO_0007989
Diseasecardiac troponin T measurement

NF1 NELFA CECR2 HSP90AB2P

1.04e-03219604EFO_0005043
Diseaseintestinal permeability measurement

PPP2R5D HSP90AB2P

1.28e-0326602EFO_0011031
Diseasediverticular disease

NF1 UPF2 PLEKHA1 SMAD3

1.37e-03236604EFO_0009959
Diseaseupper respiratory tract disorder

NEK6 SMAD3

1.49e-0328602MONDO_0004867
Diseasehair colour measurement

NEK6 MROH2A UNC13C SERINC5 TRIP11 LYST

1.54e-03615606EFO_0007822
Diseasemuscular atrophy (biomarker_via_orthology)

HSP90AB4P HSP90AB2P

1.59e-0329602DOID:767 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KEATQEAFMKRAMAN

ALDOB

321

P05062
EAFMKRAMANCQAAK

ALDOB

326

P05062
CFRKDMDKVETFLRM

CSHL1

196

Q14406
SFQFVMKMVCKDQAS

ABCA13

3241

Q86UQ4
KLFMEMNQKLFDDCT

PPP2R5D

471

Q14738
KEEFVNDMKTMFRNC

CECR2

496

Q9BXF3
KMNARQSKCYEMEDV

RAG1

976

P15918
RNCDGFLMKKEDVMN

IREB2

51

P48200
DIDKMKERAAMNNSF

KIAA0100

2101

Q14667
MAGDDKHMFKQFCQE

MAF1

36

Q9H063
EQMFAAQEMFKTANK

NELFA

436

Q9H3P2
DQKLMEFLCNMDNKD

INCENP

16

Q9NQS7
MEVMTFKEDRKALCF

GLOD5

61

A6NK44
KFDMKYMNFRVKACN

FSD1

236

Q9BTV5
MEERKAKFENLCKFM

HSP90AB2P

326

Q58FF8
MEESNVKFENLCRLM

HSP90AB4P

461

Q58FF6
EMEKERRFFQLQMCE

ASAP2

186

O43150
CFRKDMDKVETFLRM

CSH2

191

P0DML3
QFKDMNKSCDALLFM

PLVAP

146

Q9BX97
NMIKEAEEMCSKFTR

NAA16

456

Q6N069
FKKDVCAENNNNMAM

EVI2A

121

P22794
KDCNSAEAMDDFMKR

PFKFB3

176

Q16875
MNKVFWREMVECFNK

ECH1

81

Q13011
FMAQCQIFMEKSTRD

PEG10

96

Q86TG7
VQIFEMMDAKARQDC

NEK6

76

Q9HC98
FMKNSFKDVDQMFQR

GBP2

366

P32456
RMESIEKMESDFKNC

TUBGCP5

976

Q96RT8
FKEACEKRAQDLEMM

KLHL4

116

Q9C0H6
FNDETCLMMINMFDK

PEF1

151

Q9UBV8
KEMFKINQFNLMASE

GALNT1

76

Q10472
TMKNCKAAMNFFQSV

ATM

616

Q13315
FSAFQCQKKMMEVQK

ATM

2796

Q13315
KEMRATAEDFNKVMQ

ELMO2

461

Q96JJ3
EDLQKMKQFAQDFVM

PRMT3

181

O60678
TSFFQNMDGKELCKM

FLI1

156

Q01543
DTAMKRMDAFNQEKV

BIN3

86

Q9NQY0
IFRVCMDSNDDMKAV

LYST

1561

Q99698
MQMQKLNKDFTCDVE

FSIP1

211

Q8NA03
SKASCADMQKMLFEE

KIF4B

891

Q2VIQ3
QDFIDCFLMKMEKEK

CYP2C9

261

P11712
CFRKDMDKVETFLRM

CSH1

191

P0DML2
KAAMDFCMNMNTKAN

UPF2

586

Q9HAU5
KCKMRIFTVAQMDDN

SLC12A5

876

Q9H2X9
AEAKMTFKIFQMNEE

MIA2

796

Q96PC5
MEMENCTRVKEFIFL

OR4D10

1

Q8NGI6
ELMKFFFSQMETNKE

MROH2A

386

A6NES4
MENCQTLVDKFMKLD

MSH5

796

O43196
IFKNCERFNEMMKVV

TRIM33

1031

Q9UPN9
MSCKEFDDLFENMHK

TADA2B

266

Q86TJ2
RKEMREMTKSFFNAQ

NT5DC3

461

Q86UY8
VFMDVCLKEKFMDED

PRAMEF22

151

A3QJZ6
KANREKMTQIMFETF

POTEJ

776

P0CG39
CMADENCFKVMFLQR

SIN3B

946

O75182
MAMKCIEEKFQFTLS

PIH1D2

131

Q8WWB5
KYEFICRKCQMMFTD

ZFHX4

3351

Q86UP3
ACARSIFIFDEMDKM

TOR1A

161

O14656
ECIKQMSFELNQMRA

UNC13C

1856

Q8NB66
MQMVCNLREFKEFID

SSH2

281

Q76I76
QDRMECFNADLKADM

SNX30

376

Q5VWJ9
MELCEFAFNMKKDEV

SMAD3

106

P84022
MAVFYTQKDSCMENK

SERINC5

216

Q86VE9
QKAMCNETTSFEKMA

FGD6

401

Q6ZV73
FCQEMKFRNKMVEYL

NF1

1031

P21359
EMDLDFTKLQRNMAC

TEX11

451

Q8IYF3
NMKFSMMLREKEFEC

TRIP11

1486

Q15643
CKQSDIMMRDNLFEI

PLEKHA1

246

Q9HB21