Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

CLIP4 AP1AR MISP MYH11 DST BRCA1 ANK3 MICALL2 MAP4 MARK1 TLN1 TUBGCP3 CCSER2 LMTK2 MAP3K1 ADD2

3.34e-0510999116GO:0008092
GeneOntologyMolecularFunctionextracellular matrix constituent, lubricant activity

MUC17 MUC4

1.23e-044912GO:0030197
GeneOntologyMolecularFunctionphosphatidylserine binding

MARK1 TLN1 SYTL2 OSBPL8

3.46e-0473914GO:0001786
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CLIP4 MISP SRGAP2C DST BRCA1 ANK3 MAP4 MARK1 TUBGCP3 SSX2IP CCSER2 GPSM2 SRGAP2 EYA1 CDC14A PIERCE2

1.10e-077209216GO:0000226
GeneOntologyBiologicalProcessmicrotubule-based process

CLIP4 MISP SRGAP2C DST BRCA1 ANK3 ARMC3 MAP4 MARK1 TUBGCP3 SSX2IP CCSER2 GPSM2 SRGAP2 EYA1 CDC14A ARHGAP21 PIERCE2

8.36e-0710589218GO:0007017
GeneOntologyBiologicalProcessextension of a leading process involved in cell motility in cerebral cortex radial glia guided migration

SRGAP2C SRGAP2

1.97e-052922GO:0021816
GeneOntologyBiologicalProcessestablishment of spindle orientation

MISP MAP4 GPSM2 EYA1

5.24e-0546924GO:0051294
GeneOntologyBiologicalProcessreceptor recycling

AP1AR LMTK2 GRIA3 SORL1

1.06e-0455924GO:0001881
GeneOntologyBiologicalProcessprotein dephosphorylation

PPP1R2 PPP1R2B PTPRZ1 PTPN22 EYA1 CDC14A LRRD1

1.49e-04256927GO:0006470
GeneOntologyBiologicalProcessestablishment or maintenance of cell polarity

MISP DST ANK3 SPN MAP4 GPSM2 EYA1

1.53e-04257927GO:0007163
GeneOntologyBiologicalProcessdephosphorylation

PPP1R2 PPP1R2B SMG7 PTPRZ1 PTPN22 EYA1 CDC14A LRRD1

1.61e-04347928GO:0016311
GeneOntologyBiologicalProcessestablishment of spindle localization

MISP MAP4 GPSM2 EYA1

1.70e-0462924GO:0051293
GeneOntologyBiologicalProcessregulation of neuron migration

SRGAP2C PTPRZ1 SRGAP2 NRG3

1.70e-0462924GO:2001222
GeneOntologyBiologicalProcessmodulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration

SRGAP2C SRGAP2

1.95e-045922GO:0021815
GeneOntologyBiologicalProcesscell junction assembly

SRGAP2C DST MICALL2 MARK1 TLN1 SRGAP2 SRCIN1 SRGAP2B NRG3 ADD2

2.24e-045699210GO:0034329
GeneOntologyBiologicalProcessspindle localization

MISP MAP4 GPSM2 EYA1

2.29e-0467924GO:0051653
GeneOntologyBiologicalProcesspositive regulation of viral transcription

RSF1 MAP3K1

2.92e-046922GO:0050434
GeneOntologyCellularComponentpostsynapse

PPP1R2 PPP1R2B DST ANK3 MAP4 MARK1 PTPRZ1 GRIA3 NBEA SRGAP2 SRCIN1 NR1D1 ADD2

5.03e-0410189213GO:0098794
GeneOntologyCellularComponentmicrotubule end

CLIP4 MISP DST

6.22e-0438923GO:1990752
GeneOntologyCellularComponentdendritic spine

PPP1R2 PPP1R2B PTPRZ1 GRIA3 SRGAP2 NR1D1

7.03e-04242926GO:0043197
GeneOntologyCellularComponentneuron spine

PPP1R2 PPP1R2B PTPRZ1 GRIA3 SRGAP2 NR1D1

7.82e-04247926GO:0044309
GeneOntologyCellularComponentpostsynaptic density

DST ANK3 MAP4 PTPRZ1 GRIA3 SRGAP2 SRCIN1 ADD2

8.44e-04451928GO:0014069
GeneOntologyCellularComponentsynaptonemal complex

MEI4 BRCA1 HORMAD1

1.09e-0346923GO:0000795
GeneOntologyCellularComponentsynaptonemal structure

MEI4 BRCA1 HORMAD1

1.09e-0346923GO:0099086
GeneOntologyCellularComponentasymmetric synapse

DST ANK3 MAP4 PTPRZ1 GRIA3 SRGAP2 SRCIN1 ADD2

1.21e-03477928GO:0032279
GeneOntologyCellularComponentactin-based cell projection

SPN MUC17 PTPRZ1 SRCIN1 MUC4 CDC14A

1.44e-03278926GO:0098858
GeneOntologyCellularComponentpostsynaptic specialization

DST ANK3 MAP4 PTPRZ1 GRIA3 SRGAP2 SRCIN1 ADD2

1.69e-03503928GO:0099572
GeneOntologyCellularComponentspindle pole

MISP TUBGCP3 GPSM2 NSL1 CDC14A

2.13e-03205925GO:0000922
GeneOntologyCellularComponentneuron to neuron synapse

DST ANK3 MAP4 PTPRZ1 GRIA3 SRGAP2 SRCIN1 ADD2

2.15e-03523928GO:0098984
GeneOntologyCellularComponentcollagen-containing extracellular matrix

EYS DST ADAMTS3 SPN MUC17 PTPRZ1 PRG4 MUC4

2.34e-03530928GO:0062023
GeneOntologyCellularComponentextracellular matrix

EYS DST ADAMTS3 SPN MUC17 PTPRZ1 PRG4 MUC4 GP1BA

2.39e-03656929GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

EYS DST ADAMTS3 SPN MUC17 PTPRZ1 PRG4 MUC4 GP1BA

2.44e-03658929GO:0030312
GeneOntologyCellularComponentsomatodendritic compartment

PPP1R2 PPP1R2B ANK3 MARK1 PTPRZ1 KNDC1 LMTK2 GRIA3 SRGAP2 SRCIN1 NR1D1 CNGA4 SORL1

2.74e-0312289213GO:0036477
GeneOntologyCellularComponentfocal adhesion

MISP DST PPFIBP1 TLN1 SH3KBP1 SRCIN1 HMGA1

2.94e-03431927GO:0005925
GeneOntologyCellularComponentlateral element

MEI4 BRCA1

3.12e-0319922GO:0000800
GeneOntologyCellularComponentglutamatergic synapse

SRGAP2C MARK1 PTPRZ1 GRIA3 NBEA SRGAP2 SRCIN1 SRGAP2B NRG3 ADD2

3.15e-038179210GO:0098978
GeneOntologyCellularComponentcell-substrate junction

MISP DST PPFIBP1 TLN1 SH3KBP1 SRCIN1 HMGA1

3.42e-03443927GO:0030055
GeneOntologyCellularComponentanchoring junction

MISP DST ANK3 MICALL2 PPFIBP1 TLN1 SSX2IP SH3KBP1 SRCIN1 HMGA1 ARHGAP21

3.69e-039769211GO:0070161
GeneOntologyCellularComponentSUMO ligase complex

RANBP2 HMGA1

3.81e-0321922GO:0106068
GeneOntologyCellularComponentgamma-tubulin complex

BRCA1 TUBGCP3

3.81e-0321922GO:0000930
GeneOntologyCellularComponentactin cytoskeleton

MISP MYH11 DST MICALL2 SRCIN1 ARHGAP21 MAP3K1 ADD2

3.88e-03576928GO:0015629
DomainsrGAP2

SRGAP2C SRGAP2 SRGAP2B

1.08e-073903IPR030252
DomainFCH

SRGAP2C SRGAP2 SRGAP2B

1.56e-0422903PF00611
DomainFCH

SRGAP2C SRGAP2 SRGAP2B

1.56e-0422903SM00055
DomainFCH_dom

SRGAP2C SRGAP2 SRGAP2B

1.79e-0423903IPR001060
DomainF_BAR

SRGAP2C SRGAP2 SRGAP2B

2.30e-0425903IPR031160
DomainF_BAR

SRGAP2C SRGAP2 SRGAP2B

2.30e-0425903PS51741
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC17 MUC16 MUC4

4.15e-0516613M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC17 MUC16 MUC4

5.02e-0517613M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC17 MUC16 MUC4

9.70e-0521613MM15706
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC17 MUC16 MUC4

1.28e-0423613M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC17 MUC16 MUC4

1.87e-0426613M27483
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS3 MUC17 MUC16 MUC4

2.10e-0468614M27303
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

PPP1R2B RANBP2 R3HCC1L DST SMG7 MAP4 SUB1 PRRC2C TLN1 RSF1 MKI67 RPRD2 SRGAP2 HMGA1 OGA ARHGAP21 AHNAK2 ANKS1A

4.93e-11934931833916271
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP1R2 RANBP2 SMG7 ANK3 SUB1 PTPRZ1 SSX2IP PLCL2 MKI67 LMTK2 PTPN22 NBEA CACHD1 HMGA1 EYA1 RAB11FIP1 CDC14A ADD2

3.19e-101049931827880917
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DST MAP4 SUB1 PRRC2C PPFIBP1 SSX2IP CCSER2 C19orf47 OSBPL8 LMTK2 SRGAP2 RAB11FIP1 CDC14A ARHGAP21 AHNAK2 ANKS1A

1.12e-09861931636931259
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

DST ANK3 MARK1 PPFIBP1 OSBPL8 SRGAP2 CACHD1 RAB11FIP1 RALGAPA2 ARHGAP21 ADD2

1.80e-08421931136976175
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DST SMG7 CCSER2 LMTK2 TMEM131L PDCD11 RPRD2 SRCIN1 CACHD1 OGA RAI1 ANKS1A

1.85e-08529931214621295
Pubmed

Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.

SRGAP2C SRGAP2 SRGAP2B

1.85e-08393322559944
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

RANBP2 SMG7 ANK3 CCSER2 MKI67 TMEM131L ARHGAP21 AHNAK2 ANKS1A

3.90e-0826393934702444
Pubmed

Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.

SRGAP2C SRGAP2 SRGAP2B

7.39e-08493322559943
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DST SMG7 PPFIBP1 TLN1 OSBPL8 RPRD2 OGA SLC23A2

1.72e-0722593812168954
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MISP MYH11 DST ANK3 MAP4 MARK1 PTPRZ1 PRRC2C TLN1 SH3KBP1 KNDC1 OSBPL8 NBEA SRGAP2 SRCIN1 ARHGAP21 ADD2

2.25e-071431931737142655
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PPP1R2 PPP1R2B RANBP2 ANK3 MAP4 MARK1 PRRC2C SH3KBP1 KNDC1 OSBPL8 LMTK2 GRIA3 NBEA SRCIN1 HMGA1

3.50e-071139931536417873
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RANBP2 DST ANK3 MAP4 PRRC2C PPFIBP1 TLN1 OSBPL8 CACHD1 ARHGAP21 ADD2 ANKS1A

4.27e-07708931239231216
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

MISP BRCA1 MARK1 MKI67 LMTK2 PDCD11 RPRD2 NSL1 ARHGAP21

5.66e-0736193930344098
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

MAP4 SRGAP2 SRCIN1 ARHGAP21 ADD2

1.04e-066793529254152
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

RANBP2 GATAD2A BRCA1 MAP4 SUB1 PRRC2C TLN1 TUBGCP3 MKI67 PTPN22 HMGA1 AASDH RAI1 CCDC7

1.38e-061103931434189442
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

PPP1R2 MISP DST PPFIBP1 SSX2IP ARHGAP21 ANKS1A

1.57e-0620993736779422
Pubmed

Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon.

MYH11 MUC17 MKI67 MUC4

1.85e-063393416618389
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

EYS MAP4 SUB1 LMTK2 MUC16 XRRA1 HMGA1 AASDH CDC14A

1.97e-0642093928065597
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

DST ANK3 MAP4 PPFIBP1 TLN1 SH3KBP1 CCSER2 SRGAP2 SRCIN1 ARHGAP21

2.86e-06565931025468996
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

PPP1R2B RANBP2 DST MAP4 PRRC2C PPFIBP1 TLN1 OSBPL8 TMEM131L AHNAK2

2.99e-06568931037774976
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

RANBP2 SMG7 BRCA1 MAP4 PRRC2C TLN1 MKI67 SMG9 SRGAP2 HMGA1 AHNAK2

3.83e-06724931136232890
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

PPP1R2 PPP1R2B MAP4 SRCIN1 OGA ADD2 ANKS1A

4.59e-0624693715345747
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

SMG7 ANK3 PPFIBP1 TUBGCP3 SSX2IP CCSER2 ADD2

5.24e-0625193729778605
Pubmed

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.

PTPN22 NLRP3

7.07e-06293227043286
Pubmed

Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa.

PPP1R2 PPP1R2B

7.07e-06293223506001
Pubmed

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses.

SRGAP2C SRGAP2

7.07e-06293227373832
Pubmed

Pleiotrophin stimulates tyrosine phosphorylation of beta-adducin through inactivation of the transmembrane receptor protein tyrosine phosphatase beta/zeta.

PTPRZ1 ADD2

7.07e-06293216105548
Pubmed

Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice.

NLRP3 GP1BA

7.07e-06293237622117
Pubmed

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.

MUC16 MUC4

7.07e-06293223544943
Pubmed

Down-regulation of RalGTPase-Activating Protein Promotes Colitis-Associated Cancer via NLRP3 Inflammasome Activation.

RALGAPA2 NLRP3

7.07e-06293231622786
Pubmed

Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation.

SSX2IP GPSM2

7.07e-06293226751642
Pubmed

The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development.

SRGAP2C SRGAP2B

7.07e-06293231822692
Pubmed

Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.

NR1D1 NLRP3

7.07e-06293229277561
Pubmed

BRCA1 regulates HMGA2 levels in the Swan71 trophoblast cell line.

BRCA1 HMGA1

7.07e-06293231410930
Pubmed

Nonfunctioning pituitary adenomas: association of Ki-67 and HMGA-1 labeling indices with residual tumor growth.

MKI67 HMGA1

7.07e-06293224452592
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

TSHZ3 GATAD2A RSF1 MKI67 RAI1

8.73e-0610393532744500
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RANBP2 GATAD2A BRCA1 MAP4 SUB1 PRRC2C RSF1 MKI67 PDCD11 RPRD2 HMGA1 RAI1

9.19e-06954931236373674
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RANBP2 DST MAP4 PRRC2C TLN1 RSF1 MKI67 OSBPL8 PDCD11 RAI1

1.01e-05653931022586326
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

RANBP2 DST MAP4 TLN1 MKI67 OSBPL8

1.30e-0519193631177093
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC17 MUC16 MUC4

1.47e-051893318834073
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

GATAD2A MAP4 PRRC2C TUBGCP3 MKI67 RPRD2 AHNAK2

1.60e-0529893730737378
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

R3HCC1L ANK3 ARMC3 CCSER2 MKI67 KNDC1 ARHGAP21 CCDC7

1.62e-0541593816385451
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

RANBP2 DST MAP4 PRRC2C AHNAK2

2.07e-0512393526912792
Pubmed

Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.

MUC16 MUC4

2.12e-05393223053434
Pubmed

Predicting Lymph Node Metastasis in Endometrial Cancer Using Serum CA125 Combined with Immunohistochemical Markers PR and Ki67, and a Comparison with Other Prediction Models.

MKI67 MUC16

2.12e-05393227163153
Pubmed

BRCA1, Ki67, and β-Catenin Immunoexpression Is Not Related to Differentiation, Platinum Response, or Prognosis in Women With Low- and High-Grade Serous Ovarian Carcinoma.

BRCA1 MKI67

2.12e-05393229465506
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC4

2.12e-05393230236127
Pubmed

Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes.

PPP1R2 PPP1R2B

2.12e-05393224195737
Pubmed

Ki-67 and p53 expression of the fallopian tube mucosa in breast cancer patients with hereditary risk.

BRCA1 MKI67

2.12e-05393224196303
Pubmed

A novel transmembrane Ser/Thr kinase complexes with protein phosphatase-1 and inhibitor-2.

PPP1R2 LMTK2

2.12e-05393212393858
Pubmed

A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts.

MKI67 GPSM2

2.12e-05393212571286
Pubmed

Structural basis for regulation of protein phosphatase 1 by inhibitor-2.

PPP1R2 PPP1R2B

2.12e-05393217636256
Pubmed

Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).

MUC16 MUC4

2.12e-05393227483328
Pubmed

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.

MUC16 MUC4

2.12e-05393224204560
Pubmed

Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.

MUC16 MUC4

2.12e-05393224939955
Pubmed

Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.

MUC16 MUC4

2.12e-05393217592322
Pubmed

REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis.

NR1D1 NLRP3

2.12e-05393230315268
Pubmed

Prediction of BRCA1 germ-line mutation status in patients with breast cancer using histoprognosis grade, MS110, Lys27H3, vimentin, and KI67.

BRCA1 MKI67

2.12e-05393223614934
Pubmed

Two atypical enteropathogenic Escherichia coli strains induce the production of secreted and membrane-bound mucins to benefit their own growth at the apical surface of human mucin-secreting intestinal HT29-MTX cells.

MUC17 MUC4

2.12e-05393220065027
Pubmed

Association between mitogen-activated protein kinase kinase kinase 1 rs889312 polymorphism and breast cancer risk: evidence from 59,977 subjects.

BRCA1 MAP3K1

2.12e-05393220809358
Pubmed

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

MUC16 MUC4

2.12e-05393235879412
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

RANBP2 MISP MAP4 SSX2IP MKI67 NSL1

2.22e-0521093616565220
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

DST MARK1 PPFIBP1 SSX2IP CCSER2 SRGAP2 RAB11FIP1 ANKS1A

2.70e-0544693824255178
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

RANBP2 GATAD2A PRRC2C RSF1 HMGA1 EYA1 MUC4 ANKS1A

3.85e-0546993827634302
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

R3HCC1L ANK3 PPFIBP1 TLN1 TUBGCP3 SSX2IP CCSER2 OSBPL8 TMEM131L PDCD11 NSL1 RAB11FIP1 OGA ADD2

4.03e-051487931433957083
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

DST MAP4 SH3KBP1 SYTL2 NBEA SRCIN1 ADD2

4.21e-0534793717114649
Pubmed

Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice.

NR1D1 NLRP3

4.23e-05493233391484
Pubmed

Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin.

ANK3 MKI67

4.23e-05493224821222
Pubmed

Cloning and characterization of human phosphatase inhibitor-2 (IPP-2) sequences.

PPP1R2 PPP1R2B

4.23e-0549327949733
Pubmed

Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics.

MAP4 MARK1

4.23e-0549328631898
Pubmed

RANBP2 Activates O-GlcNAcylation through Inducing CEBPα-Dependent OGA Downregulation to Promote Hepatocellular Carcinoma Malignant Phenotypes.

RANBP2 OGA

4.23e-05493234298689
Pubmed

Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: Mechanisms and implications.

TLN1 GP1BA

4.23e-05493231826978
Pubmed

A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair.

BRCA1 MKI67

4.23e-05493234548335
Pubmed

TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.

MUC16 MUC4

4.23e-05493239024979
Pubmed

Association of polymorphism of NLRP3, ICAM-1, PTPN22, INS genes in childhood onset type 1 diabetes in a Pakistani population.

PTPN22 NLRP3

4.23e-05493239425874
Pubmed

Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells.

MAP4 MARK1

4.23e-05493210542369
Pubmed

A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage.

BRCA1 MKI67

4.23e-05493211420664
Pubmed

Butyrate enemas upregulate Muc genes expression but decrease adherent mucus thickness in mice colon.

MUC17 MUC4

4.23e-05493218198997
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PPP1R2 RANBP2 MAP4 SUB1 MKI67 HMGA1 NR1D1 OGA PRG4 ANKS1A

4.31e-05774931015302935
Pubmed

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

BRCA1 HMGA1 GIPC3

5.17e-052793317525332
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RANBP2 DST ANK3 PRRC2C SH3KBP1 GRIA3 NBEA SRGAP2 ARHGAP21 RAI1 ANKS1A

5.34e-05963931128671696
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MYH11 USF3 MARK1 PPFIBP1 SSX2IP SYTL2 OSBPL8 RALGAPA2

5.47e-0549393815368895
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ANK3 OSBPL8 PTPN22 NBEA SRCIN1 MUC4 ARHGAP21 RAI1

5.79e-0549793836774506
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PPP1R2 RANBP2 MISP MICALL2 SUB1 TLN1 TUBGCP3 SH3KBP1 CCSER2 MKI67 NSL1 HMGA1

5.95e-051155931220360068
Pubmed

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

BRCA1 RSF1 MKI67 RPRD2 HMGA1

6.64e-0515793530686591
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

RANBP2 MISP MAP4 PRRC2C TLN1 AHNAK2

6.69e-0525693633397691
Pubmed

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

BRCA1 MAP3K1

7.04e-05593218355772
Pubmed

Mammary-Stem-Cell-Based Somatic Mouse Models Reveal Breast Cancer Drivers Causing Cell Fate Dysregulation.

BRCA1 PTPN22

7.04e-05593227653681
Pubmed

Protein Phosphatase-1 Inhibitor-2 Is a Novel Memory Suppressor.

PPP1R2 PPP1R2B

7.04e-05593226558779
Pubmed

Multifaceted transcriptional regulation of the murine intestinal mucus layer by endogenous microbiota.

MUC17 MUC4

7.04e-05593218035521
Pubmed

Disruption of the talin gene arrests mouse development at the gastrulation stage.

TLN1 MKI67

7.04e-05593211084655
Pubmed

Regulators of the protein phosphatase PP1γ2, PPP1R2, PPP1R7, and PPP1R11 are involved in epididymal sperm maturation.

PPP1R2 PPP1R2B

7.04e-05593230144392
Pubmed

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.

PCNX2 NRG3 MAP3K1

9.53e-053393324204828
Pubmed

Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice.

MEI4 HORMAD1

1.05e-04693227723721
Pubmed

Breast cancer susceptibility variants alter risks in familial disease.

BRCA1 MAP3K1

1.05e-04693219617217
Pubmed

Rn7SK small nuclear RNA is involved in neuronal differentiation.

MKI67 HMGA1

1.05e-04693229091296
Pubmed

Principles of chromosome organization for meiotic recombination.

MEI4 HORMAD1

1.05e-04693238657614
Pubmed

Ensuring meiotic DNA break formation in the mouse pseudoautosomal region.

MEI4 HORMAD1

1.05e-04693232461690
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

RANBP2 GATAD2A MAP4 PRRC2C TLN1 OSBPL8 HMGA1 RAB11FIP1 ADD2

1.11e-0470193930196744
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SMG7 ANK3 MAP4 SUB1 PRRC2C TLN1 PDCD11 RPRD2

1.15e-0454993838280479
InteractionGSK3B interactions

PPP1R2 PPP1R2B MISP DST SMG7 MAP4 PRRC2C PPFIBP1 SSX2IP MKI67 PDCD11 EYA1 OGA ARHGAP21 MAP3K1 RAI1 ANKS1A

3.49e-078689217int:GSK3B
InteractionNAA40 interactions

PPP1R2B RANBP2 R3HCC1L DST SMG7 MAP4 SUB1 PRRC2C TLN1 RSF1 MKI67 RPRD2 SRGAP2 HMGA1 OGA ARHGAP21 AHNAK2 ANKS1A

3.73e-079789218int:NAA40
InteractionSFN interactions

PPP1R2 MYH11 DST MAP4 MARK1 SUB1 PRRC2C PPFIBP1 CCSER2 LMTK2 SRGAP2 RAB11FIP1 ARHGAP21 AHNAK2 ANKS1A

5.27e-076929215int:SFN
InteractionC11orf52 interactions

DST ANK3 MARK1 PPFIBP1 PLCL2 OSBPL8 SRGAP2 CACHD1 ARHGAP21 ADD2

1.56e-063119210int:C11orf52
InteractionATG16L1 interactions

AP1AR RANBP2 SMG7 GATAD2A ANK3 MICALL2 MAP4 PRRC2C TLN1 TUBGCP3 CCSER2 OSBPL8 LMTK2 SRGAP2 HMGA1 RAB11FIP1 NLRP3 ADD2

4.32e-0611619218int:ATG16L1
InteractionZFPL1 interactions

DST ANK3 PPFIBP1 OSBPL8 LMTK2 NBEA CACHD1 RAB11FIP1 ARHGAP21 ADD2 AHNAK2

6.17e-064489211int:ZFPL1
InteractionYWHAH interactions

MYH11 DST MARK1 SUB1 PRRC2C PPFIBP1 SSX2IP CCSER2 C19orf47 OSBPL8 LMTK2 SRGAP2 RAB11FIP1 CDC14A ARHGAP21 AHNAK2 ANKS1A

8.90e-0611029217int:YWHAH
InteractionYWHAQ interactions

MYH11 DST BRCA1 MAP4 MARK1 PPFIBP1 TLN1 TUBGCP3 SSX2IP CCSER2 C19orf47 SRGAP2 RAB11FIP1 CDC14A ARHGAP21 MAP3K1 ANKS1A

1.07e-0511189217int:YWHAQ
InteractionGOLGA1 interactions

AP1AR R3HCC1L DST SMG7 SSX2IP CCSER2 AHNAK2

2.08e-05183927int:GOLGA1
InteractionPPP1CC interactions

PPP1R2 PPP1R2B MISP BRCA1 MARK1 PLCL2 MKI67 LMTK2 PDCD11 RPRD2 NSL1 RAB11FIP1 ARHGAP21

2.97e-057389213int:PPP1CC
InteractionSTX6 interactions

AP1AR DST ANK3 PPFIBP1 OSBPL8 LMTK2 NBEA RAB11FIP1 ARHGAP21 AHNAK2

3.78e-054489210int:STX6
InteractionKCNA3 interactions

RANBP2 DST ANK3 MAP4 PRRC2C PPFIBP1 TLN1 SYTL2 OSBPL8 CACHD1 ARHGAP21 ADD2 SORL1 ANKS1A

3.91e-058719214int:KCNA3
InteractionEZR interactions

MISP R3HCC1L DST BRCA1 ANK3 SPN PPFIBP1 NBEA SRGAP2 OGA ARHGAP21

4.34e-055539211int:EZR
InteractionYWHAG interactions

DST MARK1 SUB1 PRRC2C PPFIBP1 SSX2IP CCSER2 C19orf47 OSBPL8 LMTK2 SRGAP2 RAB11FIP1 CDC14A ARHGAP21 MAP3K1 AHNAK2 ANKS1A

4.39e-0512489217int:YWHAG
InteractionYWHAE interactions

PPP1R2 MYH11 DST BRCA1 MARK1 PPFIBP1 SSX2IP CCSER2 OSBPL8 SRGAP2 SRCIN1 HMGA1 RAB11FIP1 CDC14A ARHGAP21 MAP3K1 ANKS1A

4.75e-0512569217int:YWHAE
InteractionLCK interactions

DST BRCA1 ANK3 PPFIBP1 SH3KBP1 LMTK2 PTPN22 RAB11FIP1 ARHGAP21 AHNAK2

4.98e-054639210int:LCK
InteractionPPP1CB interactions

PPP1R2 PPP1R2B MISP DST BRCA1 MICALL2 MAP4 PLCL2 LMTK2 ARHGAP21

5.55e-054699210int:PPP1CB
InteractionODF2 interactions

SMG7 BRCA1 SSX2IP CDC14A ARHGAP21 MAP3K1

8.64e-05158926int:ODF2
InteractionYWHAZ interactions

MYH11 DST BRCA1 MARK1 PPFIBP1 SSX2IP RSF1 CCSER2 OSBPL8 NSL1 SRGAP2 RAB11FIP1 CDC14A ARHGAP21 MAP3K1 GP1BA ANKS1A

8.71e-0513199217int:YWHAZ
InteractionOCLN interactions

DST ANK3 PPFIBP1 CCSER2 LMTK2 NBEA CACHD1 RAB11FIP1 ARHGAP21 ADD2

9.44e-055009210int:OCLN
InteractionLYN interactions

DST ANK3 PPFIBP1 SH3KBP1 LMTK2 GRIA3 CACHD1 RAB11FIP1 ARHGAP21 ADD2 AHNAK2 GP1BA

1.05e-047209212int:LYN
InteractionTBC1D31 interactions

MYH11 SSX2IP PTPN22 CDC14A

1.25e-0456924int:TBC1D31
InteractionNUP43 interactions

RANBP2 DST GATAD2A BRCA1 MAP4 PRRC2C RSF1 CCSER2 MKI67 PDCD11 AHNAK2

1.29e-046259211int:NUP43
InteractionRNF43 interactions

RANBP2 SMG7 ANK3 CCSER2 MKI67 TMEM131L ARHGAP21 AHNAK2 ANKS1A

1.45e-04427929int:RNF43
InteractionKCTD13 interactions

MISP MYH11 DST ANK3 MAP4 MARK1 PTPRZ1 PRRC2C TLN1 SH3KBP1 KNDC1 OSBPL8 NBEA SRGAP2 SRCIN1 ARHGAP21 ADD2

1.70e-0413949217int:KCTD13
InteractionRHOQ interactions

DST PPFIBP1 OSBPL8 SRGAP2 CACHD1 RAB11FIP1 RALGAPA2 ARHGAP21 ADD2

1.88e-04442929int:RHOQ
InteractionCDH1 interactions

DST BRCA1 ANK3 MAP4 PPFIBP1 TLN1 SH3KBP1 CCSER2 MKI67 SRGAP2 SRCIN1 ARHGAP21

1.91e-047689212int:CDH1
InteractionSTX7 interactions

AP1AR DST ANK3 PPFIBP1 OSBPL8 LMTK2 NBEA CACHD1 RAB11FIP1 ARHGAP21 ADD2

2.04e-046599211int:STX7
InteractionRPA4 interactions

RANBP2 TSHZ3 DST BRCA1 MAP4 PRRC2C TLN1 MKI67 RPRD2

2.22e-04452929int:RPA4
InteractionPPP1R3A interactions

PPP1R2 BRCA1 MKI67 LMTK2

2.23e-0465924int:PPP1R3A
InteractionAATK interactions

PPP1R2 SH3KBP1 NBEA RAB11FIP1 CDC14A AHNAK2

2.64e-04194926int:AATK
InteractionSP1 interactions

MYH11 BRCA1 SUB1 TLN1 RSF1 MKI67 HMGA1 ARHGAP21

2.66e-04365928int:SP1
InteractionGSK3A interactions

PPP1R2 PPP1R2B MISP DST SMG7 PPFIBP1 SSX2IP ARHGAP21 ANKS1A

2.70e-04464929int:GSK3A
InteractionNUMA1 interactions

RANBP2 BRCA1 TLN1 SSX2IP RSF1 MKI67 GPSM2 HMGA1 RAI1

2.92e-04469929int:NUMA1
GeneFamilyCD molecules|Mucins

MUC17 MUC16 MUC22 MUC4

4.75e-0721564648
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

SRGAP2C SRGAP2 SRGAP2B

4.77e-05235631288
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R2 BRCA1 SYTL2 MKI67 LMTK2

2.40e-04181565694
GeneFamilySterile alpha motif domain containing

SFMBT1 PPFIBP1 ANKS1A

2.56e-0388563760
CoexpressionMURARO_PANCREAS_BETA_CELL

PPP1R2 CLIP4 AP1AR RANBP2 TSHZ3 USF3 DST MARK1 PLCL2 CCSER2 OSBPL8 NBEA RAB11FIP1 SORL1

5.32e-069469214M39169
CoexpressionDURCHDEWALD_SKIN_CARCINOGENESIS_DN

CLIP4 USF3 ANK3 PTPRZ1 RAB11FIP1 OGA ADD2

4.20e-05265927M1684
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SFMBT1 RANBP2 DST BRCA1 PRRC2C TUBGCP3 CCSER2 OSBPL8 TMEM131L SRGAP2 SLC23A2 ANKS1A

4.50e-058569212M4500
CoexpressionDURCHDEWALD_SKIN_CARCINOGENESIS_DN

CLIP4 USF3 ANK3 PTPRZ1 RAB11FIP1 OGA ADD2

4.96e-05272927MM1027
CoexpressionGSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN

CLIP4 SFMBT1 SSX2IP OSBPL8 TMEM131L HORMAD1

5.70e-05190926M8457
CoexpressionGSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP

PCNX2 USF3 LMTK2 TMEM131L CDC14A ARHGAP21

6.58e-05195926M4201
CoexpressionGEORGES_CELL_CYCLE_MIR192_TARGETS

BRCA1 TUBGCP3 MKI67 CDC14A

6.78e-0562924M11038
CoexpressionTRAVAGLINI_LUNG_ALVEOLAR_EPITHELIAL_TYPE_1_CELL

CLIP4 DST VSIG2 PPFIBP1 LMTK2 SRGAP2B RAB11FIP1 ANKS1A

7.13e-05391928M41659
CoexpressionGSE17721_LPS_VS_PAM3CSK4_6H_BMDC_UP

GATAD2A PLCL2 GPSM2 PTPN22 SORL1 ANKS1A

7.36e-05199926M3918
CoexpressionNADLER_HYPERGLYCEMIA_AT_OBESITY

PPP1R2 PPP1R2B SUB1 TUBGCP3

8.67e-0566924MM631
CoexpressionDESCARTES_FETAL_LUNG_SQUAMOUS_EPITHELIAL_CELLS

VSIG2 RAB11FIP1 MUC22 NR1D1 MUC4 AHNAK2

8.91e-05206926M40237
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 SYTL2 LMTK2 MUC16 NBEA RAB11FIP1 MUC4 ARHGAP21 RAI1 SORL1

4.68e-1217993106e965e424eebef50f0202cff75f458be395cfca1
ToppCellCOVID-19-T_cells|COVID-19 / group, cell type (main and fine annotations)

PCNX2 ANK3 SYTL2 CCSER2 MKI67 PTPN22 CDC14A SORL1

6.81e-091919387f64add931b64b8d35836fa6bee9ebab593844d3
ToppCellCOVID-19-T_cells-CD4+_T_cells|COVID-19 / group, cell type (main and fine annotations)

PCNX2 ANK3 SYTL2 CCSER2 PTPN22 CDC14A SORL1

1.55e-071919370646cca78e24aeb6baa9934d3c439b797c567997
ToppCellCOVID-19-lung-CD4+_Treg|lung / Disease (COVID-19 only), tissue and cell type

PPP1R2 PCNX2 ANK3 SYTL2 PTPN22 CDC14A SORL1

1.55e-0719193773ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRZ1 SYTL2 MUC16 NBEA EYA1 MUC4 SORL1

1.98e-07198937af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

PCNX2 USF3 SMG7 RPRD2 OGA ANKS1A

1.35e-0616693632d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SFMBT1 MYH11 ANK3 OSBPL8 CDC14A MAP3K1

1.39e-06167936ced6ed9b412739c6ced622523347c10295edbf53
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C DST SRGAP2 SRGAP2B CDC14A

1.66e-061729366c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|normal_Lymph_Node / Location, Cell class and cell subclass

RANBP2 USF3 DST PPFIBP1 RAB11FIP1 RAI1

1.89e-06176936476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C DST SRGAP2 SRGAP2B CDC14A

2.09e-061799367394e77e665bf16d3733df91bb12907be460ab44
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

RANBP2 ANK3 TMEM131L SRGAP2B OGA CDC14A

2.22e-06181936f2315414e714ac86211546a935660c4be6e85f1b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C DST SRGAP2 SRGAP2B CDC14A

2.52e-061859369197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C DST SRGAP2 SRGAP2B CDC14A

2.52e-06185936ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C DST SRGAP2 SRGAP2B CDC14A

2.52e-06185936b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell18-Airway-Epithelial-Club-like_secretory|Airway / Age, Tissue, Lineage and Cell class

MISP PTPRZ1 MUC16 HMGA1 RAB11FIP1 MUC4

2.69e-06187936d1e301afcc39054ae1f867d80e564e30a137e3f8
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

ANK3 PTPRZ1 NBEA CACHD1 EYA1 MUC4

2.86e-0618993684d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PPP1R2 PPFIBP1 EYA1 RAB11FIP1 MAP3K1 ANKS1A

2.94e-061909369ce301841ce9486701fa28eb2a9929e35d476878
ToppCellIPF-Lymphoid-T|IPF / Disease state, Lineage and Cell class

SFMBT1 ANK3 SYTL2 CCSER2 PTPN22 CDC14A

2.94e-06190936d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

ANK3 PTPRZ1 MUC16 NBEA EYA1 MUC4

2.94e-0619093651ca9ef4df3220487152fcf684147730637c7cc1
ToppCellCOVID-19-lung-CD4+_Treg|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP1R2 PCNX2 ANK3 PTPN22 CDC14A SORL1

3.03e-061919365a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

SFMBT1 ANK3 SYTL2 CCSER2 PTPN22 CDC14A

3.13e-06192936eb4909574fb5fc91399463523e2737095773200a
ToppCellControl-Lymphoid-T|World / Disease state, Lineage and Cell class

SFMBT1 ANK3 SYTL2 CCSER2 PTPN22 CDC14A

3.13e-06192936253cf4d2cf88ad8c45b73779336180840bef054b
ToppCellIPF-Lymphoid-T|World / Disease state, Lineage and Cell class

SFMBT1 ANK3 SYTL2 CCSER2 PTPN22 CDC14A

3.13e-06192936b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

ARMC3 SYTL2 KNDC1 MUC16 NBEA MUC4

3.13e-061929369cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellControl-Lymphoid-T|Control / Disease state, Lineage and Cell class

SFMBT1 ANK3 SYTL2 CCSER2 PTPN22 CDC14A

3.22e-06193936af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCellGoblet_1|World / shred by cell class for nasal brushing

VSIG2 SYTL2 MUC16 RAB11FIP1 MUC4 SORL1

3.42e-06195936d9e4889a2e7b7c97c07c15b043b77837739462e4
ToppCelldroplet-Bladder-nan-3m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 VSIG2 SYTL2 RAB11FIP1 RALGAPA2 SORL1

3.42e-06195936d6e2a5a15bea16de5f7ff09318c67d46ea923203
ToppCellCOPD-Lymphoid-T|COPD / Disease state, Lineage and Cell class

SFMBT1 ANK3 SYTL2 CCSER2 PTPN22 CDC14A

3.52e-0619693630e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MISP VSIG2 SYTL2 MUC16 RAB11FIP1 MUC4

3.52e-06196936a52879a4c822c5e4be569f01f845a795e00c5f4b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MISP VSIG2 SYTL2 MUC16 RAB11FIP1 MUC4

3.52e-061969367a4d502550e9e37dc42f2ff1be3c896afe365d7f
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSHZ3 MARK1 PTPRZ1 CACHD1 EYA1 MUC4

3.63e-061979361e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MISP VSIG2 SYTL2 MUC16 RAB11FIP1 MUC4

3.63e-06197936adb4e27d73ae2e6a39d212c0ead3ac0ad62d9131
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 ARMC3 SYTL2 MUC16 NBEA MUC4

3.73e-06198936d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MISP VSIG2 SYTL2 MUC16 NBEA MUC4

3.84e-061999367223f853335492ca617dbec3e4b6872a8a463a45
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MISP VSIG2 SYTL2 MUC16 NBEA MUC4

3.84e-06199936e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MISP ARMC3 LMTK2 MUC16 RAB11FIP1 MUC4

3.96e-062009361c02a7f4047d1d2208cc522c6bb4a4989d7845bb
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

DST ANK3 PTPRZ1 CCSER2 ARHGAP21 ANKS1A

3.96e-062009362a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DST ANK3 PTPRZ1 MUC16 MUC4 AHNAK2

3.96e-06200936ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MISP ARMC3 LMTK2 MUC16 RAB11FIP1 MUC4

3.96e-0620093603051d2190244208905e1611019d4b8fd200bae0
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN TUBGCP3 PDCD11 NR1D1 SORL1

1.97e-051579350ad242320ada7bcb9e29548d3050bf4fd3a07115
ToppCellfacs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN TUBGCP3 PDCD11 NR1D1 SORL1

1.97e-05157935fe4c9556806203e57522d1986754ebe5a20aa2de
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRZ1 MUC16 NBEA EYA1 MUC4

2.22e-051619352d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

MAP4 CACHD1 CDC14A NLRP3 SORL1

2.29e-05162935810881210e015c788814e4fe8d7a24c929cf2621
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C DST SRGAP2 CDC14A

2.73e-05168935315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C DST SRGAP2 CDC14A

2.73e-05168935e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MISP VSIG2 SYTL2 MUC16 MUC4

2.80e-0516993540b557549fe08c5dc9dba359af35993d68d1640a
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

DST ANK3 PPFIBP1 RAB11FIP1 NRG3

2.88e-05170935e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

TSHZ3 PTPRZ1 CACHD1 EYA1 MUC4

2.97e-051719353965ced4be6db14265a90673502fceee425837ca
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C SRGAP2 SRGAP2B CDC14A

3.05e-05172935381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell5'-Adult-Distal_Rectal-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBEA SRGAP2 EYA1 NLRP3 MAP3K1

3.14e-05173935b335ca2a247156eba821943b2b9fc9922230b409
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRZ1 MUC16 NBEA EYA1 MUC4

3.14e-05173935464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 VSIG2 MUC16 EYA1 MUC4

3.22e-0517493542f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

RANBP2 USF3 DST PPFIBP1 RAI1

3.22e-051749352274648b80dd74f3c948a779bba3391095964c34
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C SRGAP2 SRGAP2B CDC14A

3.22e-05174935dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MISP VSIG2 MUC16 MUC22 MUC4

3.31e-051759358252ddc2ca95071381f0354aefb70c4714828491
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MISP VSIG2 MUC16 MUC22 MUC4

3.31e-051759358ccf60fc469059d7aaf4e6ce54159db2962e0060
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TSHZ3 PTPRZ1 CACHD1 EYA1 MUC4

3.50e-05177935cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TSHZ3 PTPRZ1 CACHD1 EYA1 MUC4

3.50e-05177935ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 MARK1 PTPRZ1 CACHD1 EYA1

3.59e-05178935fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC17 MUC16 GRIA3 MUC4 AHNAK2

3.69e-05179935859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

ANK3 MARK1 PTPRZ1 CACHD1 EYA1

3.69e-05179935d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 ADAMTS3 SYTL2 PLCL2 NRG3

3.69e-05179935d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC17 MUC16 GRIA3 MUC4 AHNAK2

3.79e-051809353dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC17 MUC16 GRIA3 MUC4 AHNAK2

3.79e-05180935668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C DST SRGAP2 SRGAP2B CDC14A

3.89e-051819355bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

ANK3 MARK1 CACHD1 EYA1 MUC4

3.89e-051819356d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C DST SRGAP2 SRGAP2B CDC14A

3.89e-051819358e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

ANK3 MARK1 PTPRZ1 CACHD1 EYA1

3.99e-05182935caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRZ1 MUC16 NBEA EYA1 MUC4

3.99e-051829353f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C SRGAP2 SRGAP2B CDC14A

4.10e-05183935612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C SRGAP2 SRGAP2B CDC14A

4.10e-05183935848fc6dd129150897ee339343e83c645b6e779eb
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

PTPRZ1 MUC16 NBEA EYA1 MUC4

4.10e-05183935940cbe298e9c53b5622af09264586ed823d3141f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C SRGAP2 SRGAP2B CDC14A

4.10e-05183935eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 SRGAP2C SRGAP2 SRGAP2B CDC14A

4.10e-051839357c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYS SPN PTPN22 NR1D1 CDC14A

4.10e-051839354a1e5bf58d2acd9dbceeef538b6851c1e5e91059
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANK3 PRRC2C CCSER2 CDC14A SORL1

4.21e-05184935bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH11 ANK3 GRIA3 NRG3 AHNAK2

4.32e-051859356712512100ccef456d2e2bd201d0987986c92ac9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SH3KBP1 PTPN22 MS4A14 SRGAP2 NLRP3

4.43e-05186935e152bdd837366e3e0b8bcfdb4d53f0685f2e803a
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DST PTPRZ1 PPFIBP1 HMGA1 EYA1

4.43e-0518693576535681667c8afb884fa72b6edfee9e1e46335b
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILC3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SPN SYTL2 PTPN22 NR1D1 CDC14A

4.54e-05187935a037631a01d2cce088e6522dceeb1eee806522a1
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C DST SRGAP2 SRGAP2B CDC14A

4.54e-0518793524c2a3962da364e46e98abeab5f8234376fa26bb
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICALL2 SSX2IP MKI67 GPSM2 ADD2

4.54e-05187935dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

ANK3 PTPRZ1 CACHD1 EYA1 MUC4

4.54e-051879358407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SFMBT1 ANK3 NR1D1 CDC14A SORL1

4.66e-051889353e3055dacc05a932f2beb114babf1dc76994e1af
ToppCelldroplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRCA1 ADAMTS3 SSX2IP MKI67 ADD2

4.66e-051889351a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCellLPS_only-Lymphocytic_NKT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCNX2 SYTL2 PTPN22 HMGA1 SORL1

4.66e-05188935bbe65b1c11c88ab62d8485cfc3a913ff9da89aad
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B PRG4 CDC14A

4.66e-051889359db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MISP VSIG2 SYTL2 MUC16 MUC4

4.66e-051889355901b276f2379abf486b8285957277e95f08464e
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

ANK3 SYTL2 CCSER2 MKI67 MUC4

4.66e-05188935186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B PRG4 CDC14A

4.66e-05188935047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANK3 SYTL2 CCSER2 CDC14A SORL1

4.78e-051899359ab77c6fcb573854da5922412f53d2168bda6b58
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANK3 SYTL2 CCSER2 CDC14A SORL1

4.78e-051899355a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCell5'-Adult-Distal_Rectal-Hematopoietic-Myeloid-LYVE1+_Macrophage|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

USF3 TUBGCP3 SRGAP2 EYA1 NLRP3

4.78e-051899359e3c083174a64ea78648c6d48498fc4e721b569f
ToppCellCOPD-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

DST VSIG2 PPFIBP1 RAB11FIP1 NRG3

4.78e-0518993514e8e57e4db336fbef005270647983b4edf407c0
ToppCell5'-Adult-Distal_Rectal-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

USF3 TUBGCP3 SRGAP2 EYA1 NLRP3

4.78e-051899356e19bfa52406ebe095daa99f958ec4d596ce6e39
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

TSHZ3 DST PTPRZ1 PPFIBP1 CACHD1

4.90e-051909354f15842b424eefadbfe451875e517cf70e29607f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DST PPFIBP1 LMTK2 RAB11FIP1 NRG3

4.90e-0519093530b50d183d7649146eb1e79b47ba897355f1998a
ToppCellControl-Myeloid-cDC2|Control / Disease state, Lineage and Cell class

SRGAP2C OSBPL8 SRGAP2 SRGAP2B NLRP3

4.90e-051909354e481e42353d47af7991744000403af2873f6a41
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 SYTL2 MUC16 NBEA MUC4

4.90e-051909352fdc024d3d673a0134b74b4c5a63afe924995730
ToppCellControl-Myeloid-cDC2|World / Disease state, Lineage and Cell class

SRGAP2C OSBPL8 SRGAP2 SRGAP2B NLRP3

5.02e-0519193511dfd8f38beb294f42710cfbd355cb089e1023c0
Drugent-kaurene

RANBP2 OXSM NR1D1 NLRP3

6.31e-0630924CID000440911
Drug(S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; HL60; HT_HG-U133A

ANK3 SPN MAP4 CCSER2 SLC23A2 CDC14A MAP3K1

1.49e-051969272961_UP
DrugHydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; PC3; HT_HG-U133A

SFMBT1 AP1AR ADAMTS3 TLN1 CCSER2 SMG9 SLC23A2

1.49e-051969272119_DN
DrugClofazimine [2030-63-9]; Up 200; 8.4uM; HL60; HG-U133A

SMG7 MICALL2 SPN CCSER2 PDCD11 ADD2 GP1BA

1.59e-051989271624_UP
DrugAmidopyrine [58-15-1]; Down 200; 17.2uM; HL60; HG-U133A

BRCA1 SPN SSX2IP PTPN22 RPRD2 OGA ADD2

1.69e-052009271376_DN
DrugDiphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; HL60; HG-U133A

SFMBT1 RANBP2 GATAD2A SPN RPRD2 NR1D1 OGA

1.69e-052009271994_DN
Drugdeoxynivalenol

RANBP2 MYH11 GATAD2A MAP4 SH3KBP1 MKI67 MUC16 PDCD11 PTPN22 NR1D1

2.47e-054819210ctd:C007262
Diseasepentachlorophenol measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022071
Diseaseparathion measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022070
Diseasepotassium chromate measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022072
Diseasemercuric chloride measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022068
Diseaseheptachlor epoxide measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022067
Diseasemethoxychlor measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022069
Disease4,6-dinitro-o-cresol measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022053
Disease2,4,5-trichlorophenol measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022052
Diseaseazinphos methyl measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022055
Diseasealdrin measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022054
Diseasedicofol measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022060
Diseasedisulfoton measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022062
Diseasedieldrin measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022061
Diseaseendrin measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022064
Diseaseendosulfan measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022063
Diseaseheptachlor measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022066
Diseaseethion measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022065
Diseasechlorpyrifos measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022057
Diseasecadmium chloride measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022056
Diseasediazinon measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022059
Diseasedibutyl phthalate measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0022058
Diseaseenvironmental exposure measurement

EYS MUC16 CDC14A NLRP3

7.18e-0573894EFO_0008360
DiseaseDDT metabolite measurement

EYS MUC16 CDC14A NLRP3

7.57e-0574894EFO_0007886
Diseasemucositis (biomarker_via_orthology)

MKI67 MUC4

8.94e-055892DOID:0080178 (biomarker_via_orthology)
Diseaseurticaria (is_implicated_in)

PTPN22 NLRP3

2.49e-048892DOID:1555 (is_implicated_in)
Diseaseblood cobalt measurement

EYS MUC16 CDC14A NLRP3

2.53e-04101894EFO_0007577
Diseasesuicide behaviour measurement

MKI67 SLC23A2 CCDC7

3.00e-0443893EFO_0006882
Diseasetauopathy (implicated_via_orthology)

MAP4 SH3KBP1

3.98e-0410892DOID:680 (implicated_via_orthology)
Diseaseblood nickel measurement

EYS MUC16 CDC14A NLRP3

4.87e-04120894EFO_0007583
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

GPSM2 CDC14A GIPC3

4.97e-0451893cv:CN043650
Diseasesmoking behavior, BMI-adjusted waist circumference

ADAMTS3 HMGA1 EYA1 ANKS1A

5.18e-04122894EFO_0004318, EFO_0007789
Diseasecholangiocarcinoma (is_marker_for)

MKI67 MUC16 MUC4

9.68e-0464893DOID:4947 (is_marker_for)
DiseaseHereditary hearing loss and deafness

GPSM2 EYA1 CDC14A GIPC3

1.01e-03146894cv:C0236038
Diseasenasopharyngeal neoplasm

EYS R3HCC1L NRG3 ADD2

1.15e-03151894EFO_0004252
Diseasegraft-versus-host disease (is_implicated_in)

MKI67 PTPN22

1.19e-0317892DOID:0081267 (is_implicated_in)
Diseaselate-onset myasthenia gravis

PTPN22 EYA1

1.33e-0318892EFO_1001490
DiseaseSchizophrenia

BRCA1 ANK3 ADAMTS3 PTPRZ1 PLCL2 GRIA3 HMGA1 NRG3 RAI1

1.39e-03883899C0036341
DiseaseNonsyndromic genetic hearing loss

GPSM2 CDC14A GIPC3

1.59e-0376893cv:C5680182
DiseaseGraves disease

PTPN22 MUC22 ANKS1A

1.91e-0381893EFO_0004237
Diseaseplatelet crit

GATAD2A SPN TLN1 TMEM131L RPRD2 HMGA1 NLRP3 GP1BA SORL1

2.31e-03952899EFO_0007985
Diseaseunipolar depression, neuroticism measurement

EYS ARHGAP21

2.38e-0324892EFO_0003761, EFO_0007660
Diseaseobsolete_red blood cell distribution width

GATAD2A MUC17 PRRC2C PLCL2 C19orf47 SMG9 MUC4 SLC23A2 ARHGAP21 NLRP3 MAP3K1

2.41e-0313478911EFO_0005192
Diseasetaurine measurement

MS4A14 MUC4

2.79e-0326892EFO_0010536
Diseasesystemic lupus erythematosus

SMG7 ARMC3 PTPN22 SRGAP2 NRG3 MUC22 AHNAK2 ANKS1A

2.86e-03799898MONDO_0007915

Protein segments in the cluster

PeptideGeneStartEntry
SSTTGDKPVESMQTK

CXorf66

26

Q5JRM2
MKESTTTQLKSHPET

CCDC7

1161

Q96M83
DTSTSKISVTVSNKM

C19orf47

161

Q8N9M1
TTNSMKKTKSPSSES

ADGRG4

336

Q8IZF6
TLMSTRSASTSKAPE

ADGRG4

621

Q8IZF6
SKTISQYTSETKMSP

SSX2IP

16

Q9Y2D8
SAVTLKTSKMALSPS

CDC14A

441

Q9UNH5
KMSTFVSSVKSSDSP

CACHD1

296

Q5VU97
ELASTMVETSKKTAS

GIPC3

261

Q8TF64
TTEDAVKSSATMDPT

AASDH

851

Q4L235
ASAAEMIETKSSKPV

ANKS1A

1076

Q92625
MTKTKSTSGNDDSTS

AP1AR

191

Q63HQ0
SKSYVSPPSSMEDKS

ARMC3

606

Q5W041
MTSKKDSASESTLSL

CLIP4

391

Q8N3C7
APESITSKSSIATMT

CCNB3

981

Q8WWL7
TSKSSIATMTSVGKS

CCNB3

986

Q8WWL7
SSMETSIEPKATETS

R3HCC1L

551

Q7Z5L2
SSPMGSKTKETDSPS

RAI1

1121

Q7Z5J4
KSISSPSVSSETMDK

RANBP2

2801

P49792
PDTMENSTSSKQTLK

PTPN22

726

Q9Y2R2
SKPSSFPKAMETTTT

NRG3

116

P56975
TTPTETASRKTSDMV

NSL1

241

Q96IY1
FVSKSDIKSMSSPTI

OXSM

106

Q9NWU1
KETSTEALMKSSPEE

GATAD2A

126

Q86YP4
STAEAKAATSPKATM

MISP

451

Q8IVT2
TKTKPSSAVLSSMTL

MUC16

761

Q8WXI7
TMEDTTISRSIPKSS

MUC16

4866

Q8WXI7
FTSSIKTKSAEMTIT

MUC16

5256

Q8WXI7
LADSETSKATPLMST

MUC16

5441

Q8WXI7
ADSEKTKATAPMDTT

MUC16

6906

Q8WXI7
ADSETSKATSPMFIT

MUC16

7201

Q8WXI7
ATSASTVSSDSPLKM

MUC4

4246

Q99102
SETDMPTKSTVSLSE

LRRD1

791

A4D1F6
TTTSSTPPKMMLKTS

GPSM2

521

P81274
ADLSRPKSTSTSSMK

MAP4

856

P27816
PKSTSTSSMKKTTTL

MAP4

861

P27816
TSSMKKTTTLSGTAP

MAP4

866

P27816
TEKASTKMSSLDTNT

EYS

2826

Q5T1H1
SSKMYTTSITSDPKA

SPN

41

P16150
GSETTKVSTASSKMT

MUC22

1041

E2RYF6
KVSTASSKMTTVFTE

MUC22

1046

E2RYF6
SLLPATVSMETSEKS

PPFIBP1

411

Q86W92
VKKFMETTDPSTASS

DST

4221

Q03001
SQSVSKSASKMDTTL

KIAA1109

4226

Q2LD37
AKGKSTTLTQDMSTS

MICALL2

561

Q8IY33
MKSAEPSVFTKTTAD

GRIA3

706

P42263
DTEKTMPTSKSDLEA

PCNX2

551

A6NKB5
EVKTEPMSSSETAST

EYA1

41

Q99502
RDKKSTSPSNSDTEM

PIERCE2

6

H3BRN8
DPFMSKTTSNLLSSK

LMTK2

1426

Q8IWU2
TPTTKMIAVTKSAES

TUBGCP3

501

Q96CW5
MTSLETKTSDTETEP

MKI67

851

P46013
SEKTTKSFSAGPVMS

PTPRZ1

686

P23471
VSTRMPSDSDDSLTK

RALGAPA2

1721

Q2PPJ7
KNKTSTTSSMVASAE

PPP1R2

16

P41236
DESSLSMSKSKSESK

OSBPL8

86

Q9BZF1
AMEDSSRVSPSKSTS

NR1D1

106

P20393
KTKAEPISSSISNME

BRCA1

581

P38398
TSKLAKPSTMFVSST

CCSER2

121

Q9H7U1
TPAKKMSLSSISSVG

ADAMTS3

1096

O15072
SAKITMASSLSSPVK

ANK3

1691

Q12955
SEQTMPSKSTSSHVK

MS4A14

331

Q96JA4
HMESITFSKTPKSTT

GP1BA

366

P07359
KDSSLTEMSVSSISS

MARK1

521

Q9P0L2
MDKSTAIPKASSSES

KNDC1

1501

Q76NI1
SNESSMLSTDTKKAS

HORMAD1

136

Q86X24
MAKDLSSKTALSSTE

RSF1

546

Q96T23
SSKTALSSTESCTMK

RSF1

551

Q96T23
KPTSSSVDTMSLLSK

RPRD2

741

Q5VT52
MSESSSKSSQPLASK

HMGA1

1

P17096
SMPVSKTLLTSSEAS

MUC17

751

Q685J3
LEASMPSSDTTVTFK

MAP3K1

1136

Q13233
MESGKSLAQTSKTTT

NLRP3

426

Q96P20
AQEPKSSESTLTSME

MEI4

86

A8MW99
KMPSKSLEDISSDSS

SYTL2

506

Q9HCH5
LSESSTKDSLKSMTL

RAB11FIP1

381

Q6WKZ4
MSKDSSIKITTVSLS

SORL1

2011

Q92673
SSTSSSDGDKKPMVD

TMEM131L

1326

A2VDJ0
TDKESIAESKSPEMS

OGA

501

O60502
EMTATTLETESSSSK

NBEA

1236

Q8NFP9
TVSFSSMPTEKKISS

PLCL2

121

Q9UPR0
KNLTSSSKAELSPSM

SMG7

956

Q92540
TTATPDSSKTEMDSR

SH3KBP1

251

Q96B97
DPVTTKETKAVSEMS

PRRC2C

2151

Q9Y520
DASEETSTSVMQKTP

SMG9

51

Q9H0W8
SVKSTVSETFMSKPS

SRGAP2C

421

P0DJJ0
VKSTVSETFMSKPSI

SRGAP2B

421

P0DMP2
MPKSKELVSSSSSGS

SUB1

1

P53999
ATKPEMTTTAKDKTT

PRG4

906

Q92954
TTAAPKMTKETATTT

PRG4

931

Q92954
SSKKVSMSSSEIEGN

AHNAK2

4641

Q8IVF2
EKSRSPSTESQLMSK

ADD2

526

P35612
MSQDTKVKTTESSPP

CNGA4

1

Q8IV77
MAKMTESSLPSASKT

MYH11

631

P35749
APKAIMSDKFVTSTS

PDCD11

756

Q14690
TKPSKEMSGSNETSS

SRCIN1

1141

Q9C0H9
KNTTSKSMEAGSSTE

SLC23A2

6

Q9UGH3
KNKTSTTSSMVASAE

PPP1R2B

16

Q6NXS1
ESTMLEDSVSPKKST

TLN1

416

Q9Y490
SVKSTVSETFMSKPS

SRGAP2

421

O75044
PMSISKSADLTSTAT

USF3

356

Q68DE3
TKSPSEKMVTSSPEE

TSHZ3

1021

Q63HK5
MSEKKSCSSSPTQSE

SFMBT1

731

Q9UHJ3
SSASTVTTTKSKLPM

VSIG2

311

Q96IQ7
FSMKKSTSPETKHSE

ARHGAP21

1561

Q5T5U3
EDLPTTKSTSVESEM

XRRA1

491

Q6P2D8