Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesshomologous chromosome orientation in meiotic metaphase I

BRCA2 KNL1

1.33e-053442GO:0031619
GeneOntologyBiologicalProcessmeiotic metaphase I homologous chromosome alignment

BRCA2 KNL1

4.43e-055442GO:0043060
GeneOntologyBiologicalProcessacrosome assembly

SPACA1 KNL1 EQTN

6.16e-0536443GO:0001675
GeneOntologyBiologicalProcessmitotic cell cycle process

MBTPS1 SETD2 CEP126 STIL USP37 CDC25A BRCA2 KNL1 WAC

6.59e-05854449GO:1903047
GeneOntologyBiologicalProcessmeiotic metaphase chromosome alignment

BRCA2 KNL1

6.64e-056442GO:0051311
GeneOntologyBiologicalProcesscell cycle checkpoint signaling

MBTPS1 STIL BRCA2 KNL1 WAC

9.57e-05217445GO:0000075
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

LRP2 FIGLA SNAI1 CFAP57 MED1 BRCA2 USP42 SPACA1 KNL1 EQTN

2.18e-0412354410GO:0003006
GeneOntologyBiologicalProcessmitotic cell cycle

MBTPS1 SETD2 CEP126 STIL USP37 CDC25A BRCA2 KNL1 WAC

2.42e-041014449GO:0000278
GeneOntologyBiologicalProcessin utero embryonic development

TSHZ3 SETD2 SNAI1 STIL MED1 CPT2 BRCA2

2.46e-04596447GO:0001701
GeneOntologyBiologicalProcessregulation of meiotic cell cycle phase transition

CDC25A KNL1

2.90e-0412442GO:1901993
GeneOntologyBiologicalProcesscell cycle phase transition

MBTPS1 STIL USP37 CDC25A BRCA2 KNL1 WAC

3.34e-04627447GO:0044770
GeneOntologyBiologicalProcessregulation of cell cycle process

MBTPS1 SETD2 STIL MED1 CDC25A BRCA2 KNL1 WAC

3.67e-04845448GO:0010564
GeneOntologyBiologicalProcessmembrane protein intracellular domain proteolysis

MBTPS1 ADAM9

3.98e-0414442GO:0031293
GeneOntologyBiologicalProcessmitotic cell cycle checkpoint signaling

MBTPS1 STIL KNL1 WAC

3.99e-04163444GO:0007093
GeneOntologyBiologicalProcessmeiotic cell cycle phase transition

CDC25A KNL1

4.59e-0415442GO:0044771
GeneOntologyBiologicalProcessnegative regulation of cell cycle phase transition

MBTPS1 STIL BRCA2 KNL1 WAC

5.06e-04311445GO:1901988
GeneOntologyBiologicalProcessgerm cell development

FIGLA CFAP57 BRCA2 SPACA1 KNL1 EQTN

5.25e-04482446GO:0007281
GeneOntologyBiologicalProcesschordate embryonic development

LRP2 TSHZ3 SETD2 SNAI1 STIL MED1 CPT2 BRCA2

5.83e-04906448GO:0043009
GeneOntologyBiologicalProcesssecretory granule organization

SPACA1 KNL1 EQTN

6.16e-0478443GO:0033363
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

LRP2 TSHZ3 SETD2 SNAI1 STIL MED1 CPT2 BRCA2

6.87e-04929448GO:0009792
GeneOntologyBiologicalProcessmitotic cell cycle phase transition

MBTPS1 STIL USP37 CDC25A KNL1 WAC

6.98e-04509446GO:0044772
GeneOntologyBiologicalProcesscellular response to hepatocyte growth factor stimulus

BCAR1 MED1

7.43e-0419442GO:0035729
GeneOntologyBiologicalProcesscell cycle process

MBTPS1 SETD2 CEP126 STIL MED1 USP37 CDC25A BRCA2 KNL1 WAC

7.44e-0414414410GO:0022402
GeneOntologyBiologicalProcessregulation of cell cycle phase transition

MBTPS1 STIL CDC25A BRCA2 KNL1 WAC

7.50e-04516446GO:1901987
GeneOntologyCellularComponentinner acrosomal membrane

SPACA1 EQTN

6.76e-056452GO:0002079
DomainUIM

ANKIB1 USP37

6.70e-0418402PF02809
DomainUIM

ANKIB1 USP37

9.15e-0421402SM00726
DomainUIM

ANKIB1 USP37

1.20e-0324402PS50330
DomainUIM_dom

ANKIB1 USP37

1.30e-0325402IPR003903
DomainCadherin_CS

CDH23 PCDHA5 FAT2

1.63e-03109403IPR020894
DomainCadherin

CDH23 PCDHA5 FAT2

1.81e-03113403PF00028
DomainCADHERIN_1

CDH23 PCDHA5 FAT2

1.81e-03113403PS00232
DomainCADHERIN_2

CDH23 PCDHA5 FAT2

1.86e-03114403PS50268
Domain-

CDH23 PCDHA5 FAT2

1.86e-031144032.60.40.60
DomainCA

CDH23 PCDHA5 FAT2

1.90e-03115403SM00112
DomainCadherin-like

CDH23 PCDHA5 FAT2

1.95e-03116403IPR015919
DomainCadherin

CDH23 PCDHA5 FAT2

2.05e-03118403IPR002126
DomainWW

SETD2 WAC

4.55e-0347402PF00397
DomainWW

SETD2 WAC

4.74e-0348402SM00456
DomainWW_DOMAIN_2

SETD2 WAC

5.34e-0351402PS50020
DomainWW_DOMAIN_1

SETD2 WAC

5.34e-0351402PS01159
DomainWW_dom

SETD2 WAC

5.54e-0352402IPR001202
DomainQuinoprotein_ADH-like_supfam

CFAP57 WDR36

5.75e-0353402IPR011047
DomainEGF_extracell

LRP2 ADAM9

7.32e-0360402IPR013111
DomainEGF_2

LRP2 ADAM9

7.32e-0360402PF07974
DomainUSP_CS

USP37 USP42

8.80e-0366402IPR018200
DomainUSP_1

USP37 USP42

9.85e-0370402PS00972
DomainUCH

USP37 USP42

1.01e-0271402PF00443
DomainUSP_2

USP37 USP42

1.01e-0271402PS00973
DomainUSP_3

USP37 USP42

1.04e-0272402PS50235
DomainUSP_dom

USP37 USP42

1.04e-0272402IPR028889
DomainPeptidase_C19_UCH

USP37 USP42

1.04e-0272402IPR001394
DomainEGF_3

LRP2 FAT2 ADAM9

1.38e-02235403PS50026
DomainEGF

LRP2 FAT2 ADAM9

1.38e-02235403SM00181
Pubmed

USP37 Promotes Lung Cancer Cell Migration by Stabilizing Snail Protein via Deubiquitination.

SNAI1 USP37

1.71e-06246231998374
Pubmed

PLAGL2 promotes the proliferation and migration of gastric cancer cells via USP37-mediated deubiquitination of Snail1.

SNAI1 USP37

5.13e-06346233391500
Pubmed

Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].

PEAK1 BCAR1

5.13e-06346220534451
Pubmed

Quercetin suppresses the metastatic ability of lung cancer through inhibiting Snail-dependent Akt activation and Snail-independent ADAM9 expression pathways.

SNAI1 ADAM9

1.03e-05446228648644
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZNF462 LRP2 TSHZ3 RESF1 BRCA2 KNL1

1.81e-0541846634709266
Pubmed

From midbody protein-protein interaction network construction to novel regulators in cytokinesis.

URB2 CEP126

2.56e-05646219799413
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF462 SETD2 FAT2 PEAK1 USP37 WAC

4.56e-0549346615368895
Pubmed

Mutation of the novel gene Tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss DFNB6.

LTF CDC25A

1.32e-041346212140191
Pubmed

Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

STIL KNL1

2.03e-041646220301772
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

WDR36 USP37 CDC25A KNL1

2.53e-0423246425515538
Pubmed

DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.

SETD2 WDR36 MED1

3.11e-049946334161765
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

RESF1 USP37 KNL1

3.30e-0410146310997877
Pubmed

Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types.

SNAI1 ADAM9

3.89e-042246224310815
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZNF462 CDH23 WAC

3.90e-0410746311347906
Pubmed

Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.

USP37 USP42

4.25e-042346214715245
Pubmed

USP37 is a SNAI1 deubiquitinase.

SNAI1 USP37

4.64e-042446231911859
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

ZNF462 TSHZ3 SETD2 KNL1

5.28e-0428246423667531
Pubmed

Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.

LRP2 MED1

5.45e-042646228087629
Pubmed

Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse.

LRP2 SNAI1

5.88e-042746231308417
Pubmed

Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.

CDH23 CFAP57

6.33e-042846224322204
Pubmed

Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming.

MED1 CPT2

6.33e-042846228159809
Pubmed

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.

WDR36 MED1 WAC

7.52e-0413446325452129
Pubmed

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

PPP1R3A LRP2

8.28e-043246225189868
Pubmed

OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.

USP37 USP42

8.28e-043246233669244
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

LRP2 PCDHA5 BCAR1 BRCA2

9.38e-0432946417474147
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF462 URB2 LTF WDR36 USP42 ADAM9 WAC

9.58e-04120346729180619
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

SETD2 BCAR1 RESF1 BRCA2 KNL1

1.05e-0358846538580884
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

CDH23 FAT2 STIL

1.08e-0315246334299191
InteractionNAA11 interactions

STIL CDC25A BRCA2 KNL1

1.01e-0562444int:NAA11
Cytoband1p32

STIL CPT2

3.39e-04274621p32
GeneFamilyCadherin related

CDH23 FAT2

3.81e-041731224
GeneFamilyUbiquitin specific peptidases

USP37 USP42

4.14e-0356312366
GeneFamilyAnkyrin repeat domain containing

ANKIB1 TRANK1 POTEH

8.07e-03242313403
ToppCellproximal-3-Epithelial-Proliferating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAT2 STIL CDC25A BRCA2 KNL1

1.90e-061994652263bb73d9c5693b44d91d2548305efc1b6e4079
ToppCellproximal-Epithelial-Proliferating_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAT2 STIL CDC25A BRCA2 KNL1

1.90e-06199465521ff4ae3437c8ba477a0a42b9da195af976c3ff
ToppCellproximal-Epithelial-Proliferating_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAT2 STIL CDC25A BRCA2 KNL1

1.90e-06199465e8549b2c4152cb23548351d9cee27c3805892cd8
ToppCell10x5'-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

CCDC168 STIL CDC25A KNL1

2.08e-05157464d4da4057917dda066da0f2aac2621fdaf1fb943b
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

STIL CDC25A BRCA2 KNL1

2.58e-05166464c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL CDC25A BRCA2 KNL1

2.65e-05167464108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 TRANK1 LTF PIK3C2G

2.77e-0516946412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STIL CDC25A POTEH KNL1

2.90e-0517146413126a3fbee181412c13ffb0c347277b9d8f16f7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRAF3IP3 TRANK1 DENND1B RESF1

2.90e-05171464e6dfbd2652b67577c8834c05348f62150637f348
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRAF3IP3 TRANK1 DENND1B RESF1

2.90e-05171464ddaeb96ce9c9c3bf232b4a42266fa2ee7e8f3f41
ToppCellDividing_Macrophages-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

STIL CDC25A BRCA2 KNL1

3.39e-051784641893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL CDC25A BRCA2 KNL1

3.47e-0517946488d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CDH23 TSHZ3 CDC25A KNL1

4.03e-051864645cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TRANK1 RESF1 MED1 USP37

4.03e-0518646403db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL BRCA2 PIK3C2G KNL1

4.11e-05187464057569c9437219ecc396aa6e673b1178a2273837
ToppCell10x5'-Liver-Lymphocytic_NK-Cycling_NK|Liver / Manually curated celltypes from each tissue

STIL CDC25A BRCA2 KNL1

4.20e-051884645eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

TSHZ3 SNAI1 PEAK1 ADH1A

4.20e-051884643f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellPBMC-Severe-cDC_12|Severe / Compartment, Disease Groups and Clusters

USP37 CDC25A BRCA2 KNL1

4.38e-0519046484ee185939bdefb10705b621a70da27701eadcee
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T|GI_small-bowel / Manually curated celltypes from each tissue

STIL CDC25A BRCA2 KNL1

4.47e-05191464e642fa7395c05fb53324c9d46bbc52f89fc9673f
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

DENND1B MED1 USP37 AVL9

4.65e-05193464abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STIL CDC25A BRCA2 KNL1

4.65e-05193464e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STIL CDC25A BRCA2 KNL1

4.75e-05194464f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

STIL CDC25A BRCA2 KNL1

4.75e-05194464a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STIL CDC25A BRCA2 KNL1

4.75e-0519446417744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCell3'_v3-blood-Lymphocytic_NK-Cycling_NK|blood / Manually curated celltypes from each tissue

STIL CDC25A BRCA2 KNL1

4.75e-05194464bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCellControl-Lymphoid_T/NK-T/NK_proliferative|Control / Disease group, lineage and cell class

STIL CDC25A BRCA2 KNL1

4.75e-051944649bbb124001fba7450f4639f47f9b720a483e7242
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

STIL CDC25A BRCA2 KNL1

4.75e-05194464e14f66f7584909621b776292fbd52808273fd2ee
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

STIL CDC25A BRCA2 KNL1

4.84e-05195464957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STIL CDC25A BRCA2 KNL1

4.84e-0519546475759fd7f925725f0ecd07214afcca5aa2158f9e
ToppCellmild-Lymphocytic-Prol._cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

STIL CDC25A BRCA2 KNL1

4.84e-051954649a8cc9097a349fd0a53ccf2723ee8bb1418d6aca
ToppCellHealthy-T/NK_proliferative|Healthy / disease group, cell group and cell class

STIL CDC25A BRCA2 KNL1

4.94e-0519646491e44aabb2e85dcc77ddae6f7e000118d45d1de6
ToppCellControl-T/NK_proliferative|Control / Disease condition and Cell class

STIL CDC25A BRCA2 KNL1

4.94e-051964647b7bc25aef49bfd64f79303a92d527bf8188f7a6
ToppCellmild-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

STIL CDC25A BRCA2 KNL1

4.94e-05196464b1d9866d5dfaefdb8bedaf01a750d97987acb3d1
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

STIL CDC25A BRCA2 KNL1

5.04e-0519746421861d8b389fafbdb7c3499684c9b6deee3dbd5e
ToppCellsevere_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

STIL CDC25A BRCA2 KNL1

5.04e-05197464189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

STIL CDC25A BRCA2 KNL1

5.04e-051974644b13335a43b9d6abc8e542e72440da7feb82fbe6
ToppCellHealthy/Control-T/NK_proliferative|World / Disease group and Cell class

STIL CDC25A BRCA2 KNL1

5.04e-051974644a4d3083938783d6f5b87da02f10e501917da0b4
ToppCellCOVID-19_Severe-T/NK_proliferative|COVID-19_Severe / Disease condition and Cell class

STIL CDC25A BRCA2 KNL1

5.04e-05197464718a84e9a8248080f2d964e7c6a3ba183ece9592
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

STIL CDC25A BRCA2 KNL1

5.04e-05197464ffb004c37cdd26cb7cdcd80f769a2eded65416dc
ToppCellHealthy_donor-T/NK_proliferative|Healthy_donor / disease group, cell group and cell class (v2)

STIL CDC25A BRCA2 KNL1

5.04e-05197464b6bbf87e5823fa66b4cad6a7be4f777356887b59
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK-Cycling_NK|lymph-node_spleen / Manually curated celltypes from each tissue

STIL CDC25A BRCA2 KNL1

5.14e-05198464b2868a897dd96494cf1829c30e0ce508f52efdf3
ToppCellmedial-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

STIL CDC25A BRCA2 KNL1

5.14e-0519846464a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCellCOVID-19_Moderate-T/NK_proliferative|COVID-19_Moderate / disease group, cell group and cell class

STIL CDC25A BRCA2 KNL1

5.14e-05198464166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCellmedial-Hematologic-Proliferating_Macrophage-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

STIL CDC25A BRCA2 KNL1

5.14e-05198464fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCellsevere_COVID-19-T/NK_proliferative|severe_COVID-19 / disease group, cell group and cell class (v2)

STIL CDC25A BRCA2 KNL1

5.14e-05198464ed86b0247006befe55400c287d334d2202b470bd
ToppCellsevere-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

STIL CDC25A BRCA2 KNL1

5.14e-051984644d8591eabb543ed789f963b507a07c560c76a7c9
ToppCellCOVID-19_Severe-T/NK_proliferative|World / disease group, cell group and cell class

STIL CDC25A BRCA2 KNL1

5.14e-0519846448045689d0969ff0a14eee7086b8e19b0d6b6065
ToppCellCOVID-19_Moderate-T/NK_proliferative|World / disease group, cell group and cell class

STIL CDC25A BRCA2 KNL1

5.14e-05198464bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCellmedial-Hematologic-Proliferating_Macrophage|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

STIL CDC25A BRCA2 KNL1

5.14e-05198464da6963184c32761c896a9b91a5321ad84b583736
ToppCellT_cells-GZMK+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

STIL CDC25A BRCA2 KNL1

5.14e-05198464085ba270f9defbf5ef45108c6d870e1d7c428479
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

STIL CDC25A BRCA2 KNL1

5.24e-0519946411c3d9fe811a4619347f47d2b0e94066e3085625
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STIL CDC25A BRCA2 KNL1

5.24e-05199464e0fcec796afe75e42467ca86355b9fc5aa9ae0a1
ToppCellCOVID-19_Mild-T/NK_proliferative|COVID-19_Mild / Disease condition and Cell class

STIL CDC25A BRCA2 KNL1

5.24e-051994649f9a88d2b099646c1e1a7ee3f8d39cb1a2498ad7
ToppCellmild_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

STIL CDC25A BRCA2 KNL1

5.24e-05199464d44cc74d7171d96add61dae821daf774b17d4c69
ToppCellHealthy_donor-T/NK_proliferative|World / disease group, cell group and cell class (v2)

STIL CDC25A BRCA2 KNL1

5.24e-051994641311dfd74b991f48b047a439f04f9bf7dfaa0e7a
ToppCellVE-cycling|VE / Condition, Cell_class and T cell subcluster

STIL CDC25A BRCA2 KNL1

5.24e-0519946447c47ebc318a0b98841ca2656837bbd068899559
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STIL CDC25A BRCA2 KNL1

5.24e-0519946436c80907b2ec1cbcd1b4e841e6c02a4792591d74
ToppCellVE-cycling-|VE / Condition, Cell_class and T cell subcluster

STIL CDC25A BRCA2 KNL1

5.24e-05199464c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

CCDC168 LTF STIL CDC25A

5.24e-05199464e222b90caf45904d8f763574e7b6aac13333df92
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

STIL CDC25A BRCA2 KNL1

5.24e-05199464bf4c31902ae8358215245a2e11b5a2fe4ca1bc8c
ToppCellCOVID-19_Mild-Lymphoid_T/NK-T/NK_proliferative|COVID-19_Mild / Disease group, lineage and cell class

STIL CDC25A BRCA2 KNL1

5.24e-05199464ddea0e5c1cb6a096ab8e09a8c3c37c1bff381d9c
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

STIL CDC25A BRCA2 KNL1

5.24e-0519946498575fcce726589e93fbb4df1aab03e57cb56076
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

STIL CDC25A BRCA2 KNL1

5.24e-05199464101f78fe6dd1bf9e2e4dd5ad8a970312b3540927
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STIL CDC25A BRCA2 KNL1

5.24e-051994647beb0e07a27fea94674f24eb61c381b0de38ed3e
ToppCellmild_COVID-19-T/NK_proliferative|mild_COVID-19 / disease group, cell group and cell class (v2)

STIL CDC25A BRCA2 KNL1

5.24e-05199464df2fcaf01b1b48632f84e7355ef21d20853f0664
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte-|healthy_donor / Disease condition, Lineage, Cell class and subclass

STIL CDC25A BRCA2 KNL1

5.34e-05200464415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCelldistal-Hematologic-Proliferating_Macrophage|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

STIL CDC25A BRCA2 KNL1

5.34e-052004643835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCelldistal-Hematologic-Proliferating_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

STIL CDC25A BRCA2 KNL1

5.34e-052004649c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

STIL CDC25A BRCA2 KNL1

5.34e-0520046404bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CEP126 CFAP57 PIK3C2G C1orf87

5.34e-0520046496701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

STIL CDC25A BRCA2 KNL1

5.34e-05200464e4eb915c29909cf8535a3603c68976545c05e54b
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_vent / Disease condition, Lineage, Cell class and subclass

STIL CDC25A BRCA2 KNL1

5.34e-052004647e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCellBL-critical-LOC-Lymphoid-Treg|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

STIL CDC25A BRCA2 KNL1

5.34e-0520046404d95a9102248e98eed069840ea6d3d23a243fd5
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

STIL CDC25A BRCA2 KNL1

5.34e-05200464f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCelldistal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

STIL CDC25A BRCA2 KNL1

5.34e-052004641b65c97e8123d0572d31525d6a10bc7f16857959
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

STIL CDC25A BRCA2 KNL1

5.34e-052004649775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Pvalb_(Non-anterior_nuclei)|Thalamus / BrainAtlas - Mouse McCarroll V32

PPP1R3A STIL PIK3C2G

9.98e-0587463fd0df79b02f96463a6bad90dcd019c59c8e3eb0e
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R3A FIGLA BRCA2

1.65e-04103463eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)-|Striatum / BrainAtlas - Mouse McCarroll V32

LRP2 ZSWIM2 C1orf87

2.40e-0411746326dec09112532f351fb7a2202bae84c365707b40
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)|Striatum / BrainAtlas - Mouse McCarroll V32

LRP2 ZSWIM2 C1orf87

2.40e-04117463db053c874e6739052dff1f91643e51b306236237
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)--|Striatum / BrainAtlas - Mouse McCarroll V32

LRP2 ZSWIM2 C1orf87

2.40e-0411746380780223502d18f0d86a29ff3cb74aa8235103c7
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL|Striatum / BrainAtlas - Mouse McCarroll V32

LRP2 ZSWIM2 C1orf87

2.40e-0411746340889f4a387846abbf54469cc4faf616bfe348d0
ToppCellStriatum-Macroglia-CSF_related|Striatum / BrainAtlas - Mouse McCarroll V32

LRP2 ZSWIM2 C1orf87

2.40e-04117463e12e37e393257db85f7f5c13454095c44f59d374
ToppCellCOVID-19_Mild-immature_Neutrophil-|COVID-19_Mild / Disease condition and Cell class

LTF CFAP57 CDC25A

2.78e-041234635f19b0e32509bedeb9ac6c74ac7a20750798da5e
ToppCellCOVID-19_Mild-immature_Neutrophil|COVID-19_Mild / Disease condition and Cell class

LTF CFAP57 CDC25A

2.78e-04123463a6670825fd8d9f9a0111a7b68598c764c99abb0d
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CCDC168 SPACA1 KNL1

2.84e-041244631483be8700eca7e2c288784a290d945d4022b17f
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LTF CFAP57 KNL1

2.98e-041264636cb89754010d64875e115da6c5805efac7a4a82d
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LTF CFAP57 KNL1

2.98e-0412646369b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_-_proliferative|E16.5-samps / Age Group, Lineage, Cell class and subclass

PPP1R3A SPACA1 KNL1

3.73e-0413646396370f0e3abf1c9ec7a91595b5d0f97ac2ab4b78
ToppCellPBMC-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

PEAK1 CDC25A LYSMD3

5.26e-04153463db1a6914f2033fb0748e0523cffe5d6dc4e901be
ToppCellCiliated_cells-A-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CEP126 CFAP57 C1orf87

5.36e-041544633b938e23324f7edb56797b4a76fb96ff588142cf
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

SNAI1 LTF ADH1A

5.88e-04159463b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSHZ3 FIGLA USP42

5.88e-04159463ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ3 PEAK1 SPACA1

5.88e-04159463d2de9391b00b6c47f5fe28a1bad6da2097107ee0
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TSHZ3 FIGLA USP42

5.88e-041594632f6c60ddff2208a68146f9786143d9aefd528840
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ3 PEAK1 SPACA1

5.88e-04159463da6b7f8039adc19839d6c090a0b3d68fb6445a79
ToppCellBL-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SNAI1 WDR36 SIGLEC8

6.21e-0416246325ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STIL BRCA2 KNL1

6.32e-041634635285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STIL BRCA2 KNL1

6.32e-041634633f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STIL BRCA2 KNL1

6.55e-04165463eec2d327c94832d1390314c93ef6a2be4648478b
DiseaseProstatic Neoplasms

LRP2 MBTPS1 SETD2 BCAR1 BRCA2 ADAM9 WAC

3.81e-05616457C0033578
DiseaseMalignant neoplasm of prostate

LRP2 MBTPS1 SETD2 BCAR1 BRCA2 ADAM9 WAC

3.81e-05616457C0376358
DiseaseAutosomal recessive primary microcephaly

STIL KNL1

2.36e-0415452cv:C3711387
DiseasePrimary microcephaly

STIL KNL1

5.15e-0422452C0431350
DiseaseAutosomal Recessive Primary Microcephaly

STIL KNL1

5.15e-0422452C3711387
Diseasesuicidal ideation

CDH23 WDR36

8.99e-0429452EFO_0004320

Protein segments in the cluster

PeptideGeneStartEntry
YTEAASSKQLENQNP

URB2

1036

Q14146
PKFTSQDSPDGQYEN

BCAR1

641

P56945
NPESNYCLKNDVSNP

ADH1A

106

P07327
NNPQLKESLDPNTSY

ANKIB1

26

Q9P2G1
SEYKENETPRNPQNS

ANKRD26P1

221

Q6NSI1
NDNNPIFDQPSYQEA

CDH23

2396

Q9H251
SAASDYPQQNKAAAD

C1orf87

261

Q8N0U7
AFNPDPKSEYNDQLT

CPT2

136

P23786
QTDPNPNESHEKQYE

PIK3C2G

6

O75747
KLYSQDSQSPAAQQE

LYSMD3

291

Q7Z3D4
NNPSSDYPSDFEVIQ

MBTPS1

91

Q14703
VDPQSNDPSQSDKQD

CFAP57

326

Q96MR6
TDENDNPPQFKASEY

FAT2

2576

Q9NYQ8
KEIEPNYESPSSNNQ

PEAK1

381

Q9H792
PYLDKDSPQSADCNQ

KNL1

676

Q8NG31
NVDNKNYGSPINPSE

LRP2

4546

P98164
DVNDNAPAFAQPQYT

PCDHA5

446

Q9Y5H7
ENNFENPKNTDTYIP

PPP1R3A

271

Q16821
APYPFAVENQNEAEN

C3orf14

106

Q9HBI5
PAEESEHKNNNYEPN

BRCA2

46

P51587
EYFNSKEQNPSPLNG

CEP126

341

Q9P2H0
EDSSKGQEPNDTNQY

AVL9

301

Q8NBF6
ESNNPYKPQSDKSET

CENPJ

81

Q9HC77
YESDGKNQANPSRQP

ADAM9

736

Q13443
DSKKQDPDEQSYSNN

FIGLA

126

Q6QHK4
SQPESKASNFAQPED

CCDC168

331

Q8NDH2
DHTPNYAPANEKNGN

EQTN

46

Q9NQ60
DYKPTNKSNAPSENN

DENND1B

601

Q6P3S1
TENNDSETAENYAPP

SPACA1

51

Q9HBV2
FQTNNNENPYTDPAD

MED1

826

Q15648
GSDYEQPLEVKNNSN

CDC25A

56

P30304
AENYKSQQSSDPDPN

LTF

431

P02788
DASSNYTPQDPARNE

RESF1

1026

Q9HCM1
KPQDPQGQEATDSEY

SIGLEC8

456

Q9NYZ4
NPSNNPSKTSDAPYD

WAC

116

Q9BTA9
EGPTIKNDASQQTNY

TRAF3IP3

171

Q9Y228
SDPNRKPNYSELQDS

SNAI1

11

O95863
KPNYSELQDSNPEFT

SNAI1

16

O95863
PPDNADSKSEYLLNQ

STIL

1141

Q15468
KASESSDPSAYQNQP

USP42

6

Q9H9J4
NNEEAESKQNPGSIY

SNURFL

76

B1AK76
SDTNDALQKNSNPYI

TSHZ3

346

Q63HK5
DFSQEKPSTTYQQPD

SETD2

1261

Q9BYW2
ELNTPQSPKDAYENT

ZSWIM2

451

Q8NEG5
NEDYPKENDSSSNNK

USP37

216

Q86T82
SNDSSYSEPPDVQQQ

ZNF462

2141

Q96JM2
NPTEFDYLNPNVQDS

TRANK1

531

O15050
TPESQQFPDTENEQY

POTEH

491

Q6S545
YAAPEQNNDPQQSKV

WDR36

801

Q8NI36