Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nicotinamide-nucleotide adenylyltransferase activity	NMNAT1 NMNAT3	1.23e-05	3	41	2	GO:0000309
GeneOntologyMolecularFunction	nicotinate-nucleotide adenylyltransferase activity	NMNAT1 NMNAT3	2.46e-05	4	41	2	GO:0004515
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A4 SLC4A5	6.14e-05	6	41	2	GO:0008510
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC4A4 SLC4A5	3.16e-04	13	41	2	GO:0140410
GeneOntologyMolecularFunction	neurexin family protein binding	SYTL4 SYTL2	4.85e-04	16	41	2	GO:0042043
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH17 DNAH1	6.16e-04	18	41	2	GO:0008569
GeneOntologyMolecularFunction	S-adenosyl-L-methionine binding	GNMT METTL14	1.01e-03	23	41	2	GO:1904047
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH17 DNAH1	1.50e-03	28	41	2	GO:0051959
GeneOntologyMolecularFunction	adenylyltransferase activity	NMNAT1 NMNAT3	1.84e-03	31	41	2	GO:0070566
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC4A4 SLC4A5	1.96e-03	32	41	2	GO:0015106
GeneOntologyMolecularFunction	solute:inorganic anion antiporter activity	SLC4A4 SLC4A5	1.96e-03	32	41	2	GO:0005452
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH17 DNAH1	2.62e-03	37	41	2	GO:0045505
GeneOntologyMolecularFunction	antiporter activity	SLC9B1P1 SLC4A4 SLC4A5	2.84e-03	138	41	3	GO:0015297
GeneOntologyMolecularFunction	nucleotidyltransferase activity	NMNAT1 TERF2 NMNAT3	3.73e-03	152	41	3	GO:0016779
GeneOntologyCellularComponent	I band	PYGM REM1 DST RYR1	3.09e-04	166	41	4	GO:0031674
GeneOntologyCellularComponent	sarcoplasmic reticulum	PYGM HSP90B1 RYR1	6.85e-04	88	41	3	GO:0016529
GeneOntologyCellularComponent	axonemal dynein complex	DNAH17 DNAH1	1.09e-03	25	41	2	GO:0005858
GeneOntologyCellularComponent	sarcomere	PYGM REM1 DST RYR1	1.41e-03	249	41	4	GO:0030017
GeneOntologyCellularComponent	sarcoplasm	PYGM HSP90B1 RYR1	1.45e-03	114	41	3	GO:0016528
GeneOntologyCellularComponent	supramolecular fiber	EML2 PYGM REM1 DST NUDC RYR1 DNAH17 DNAH1	1.81e-03	1179	41	8	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	EML2 PYGM REM1 DST NUDC RYR1 DNAH17 DNAH1	1.88e-03	1187	41	8	GO:0099081
GeneOntologyCellularComponent	endoplasmic reticulum protein-containing complex	HSP90B1 EXT2 RYR1	1.88e-03	125	41	3	GO:0140534
GeneOntologyCellularComponent	myofibril	PYGM REM1 DST RYR1	1.97e-03	273	41	4	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	PYGM REM1 DST RYR1	2.45e-03	290	41	4	GO:0043292
GeneOntologyCellularComponent	Z disc	PYGM DST RYR1	3.22e-03	151	41	3	GO:0030018
GeneOntologyCellularComponent	transport vesicle	CD74 MYOF SYTL4 SPTBN2 SYTL2	3.32e-03	519	41	5	GO:0030133
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	DST TERF2 DNAH17 DNAH1	3.38e-03	317	41	4	GO:0032838
GeneOntologyCellularComponent	exocytic vesicle	MYOF SYTL4 SPTBN2 SYTL2	3.49e-03	320	41	4	GO:0070382
GeneOntologyCellularComponent	smooth endoplasmic reticulum	HSP90B1 RYR1	3.68e-03	46	41	2	GO:0005790
GeneOntologyCellularComponent	microtubule	EML2 DST NUDC DNAH17 DNAH1	3.72e-03	533	41	5	GO:0005874
GeneOntologyCellularComponent	microtubule associated complex	EML2 DNAH17 DNAH1	3.86e-03	161	41	3	GO:0005875
GeneOntologyCellularComponent	dynein complex	DNAH17 DNAH1	5.04e-03	54	41	2	GO:0030286
GeneOntologyCellularComponent	motile cilium	SLC9B1P1 AK7 DNAH17 DNAH1	5.05e-03	355	41	4	GO:0031514
GeneOntologyCellularComponent	cytoplasmic region	DST TERF2 DNAH17 DNAH1	5.30e-03	360	41	4	GO:0099568
Domain	NAMN_adtrnsfrase	NMNAT1 NMNAT3	1.41e-05	3	41	2	IPR005248
Domain	Spectrin	DST KALRN SPTBN2	1.69e-05	23	41	3	PF00435
Domain	Spectrin_repeat	DST KALRN SPTBN2	3.45e-05	29	41	3	IPR002017
Domain	Spectrin/alpha-actinin	DST KALRN SPTBN2	4.66e-05	32	41	3	IPR018159
Domain	SPEC	DST KALRN SPTBN2	4.66e-05	32	41	3	SM00150
Domain	Na/HCO3_transpt	SLC4A4 SLC4A5	4.68e-05	5	41	2	IPR003024
Domain	GOLGA6L	GOLGA6L6 GOLGA6L2	7.01e-05	6	41	2	IPR026737
Domain	Cyt_trans-like	NMNAT1 NMNAT3	9.81e-05	7	41	2	IPR004821
Domain	CTP_transf_like	NMNAT1 NMNAT3	9.81e-05	7	41	2	PF01467
Domain	Band3_cytoplasmic_dom	SLC4A4 SLC4A5	1.68e-04	9	41	2	IPR013769
Domain	Band_3_cyto	SLC4A4 SLC4A5	1.68e-04	9	41	2	PF07565
Domain	-	SLC4A4 SLC4A5	1.68e-04	9	41	2	3.40.1100.10
Domain	PTrfase/Anion_transptr	SLC4A4 SLC4A5	2.09e-04	10	41	2	IPR016152
Domain	HCO3_cotransp	SLC4A4 SLC4A5	2.09e-04	10	41	2	PF00955
Domain	HCO3_transpt_euk	SLC4A4 SLC4A5	2.09e-04	10	41	2	IPR003020
Domain	HCO3_transpt_C	SLC4A4 SLC4A5	2.09e-04	10	41	2	IPR011531
Domain	FYVE_2	SYTL4 SYTL2	2.55e-04	11	41	2	PF02318
Domain	RABBD	SYTL4 SYTL2	3.06e-04	12	41	2	PS50916
Domain	Rab_BD	SYTL4 SYTL2	3.06e-04	12	41	2	IPR010911
Domain	Actinin_actin-bd_CS	DST SPTBN2	1.16e-03	23	41	2	IPR001589
Domain	ACTININ_2	DST SPTBN2	1.16e-03	23	41	2	PS00020
Domain	ACTININ_1	DST SPTBN2	1.16e-03	23	41	2	PS00019
Domain	C2	MYOF SYTL4 SYTL2	2.96e-03	131	41	3	PF00168
Domain	C2	MYOF SYTL4 SYTL2	3.36e-03	137	41	3	SM00239
Domain	C2	MYOF SYTL4 SYTL2	3.71e-03	142	41	3	PS50004
Domain	Rossmann-like_a/b/a_fold	NMNAT1 NMNAT3	4.01e-03	43	41	2	IPR014729
Domain	-	NMNAT1 NMNAT3	4.01e-03	43	41	2	3.40.50.620
Domain	-	MYOF SYTL4 SYTL2	4.17e-03	148	41	3	2.60.40.150
Domain	fn3	IL31RA KALRN ANKFN1	5.36e-03	162	41	3	PF00041
Domain	C2_dom	MYOF SYTL4 SYTL2	5.55e-03	164	41	3	IPR000008
Domain	Quinoprotein_ADH-like_supfam	EML2 EIF2AK3	6.04e-03	53	41	2	IPR011047
Pubmed	Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy.	NMNAT1 NMNAT3	1.64e-06	2	45	2	16914673
Pubmed	Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis.	NMNAT1 NMNAT3	1.64e-06	2	45	2	12574164
Pubmed	NMNAT Proteins that Limit Wallerian Degeneration Also Regulate Critical Period Plasticity in the Visual Cortex.	NMNAT1 NMNAT3	1.64e-06	2	45	2	30671537
Pubmed	Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.	NMNAT1 NMNAT3	1.64e-06	2	45	2	11788603
Pubmed	Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration.	NMNAT1 NMNAT3	1.64e-06	2	45	2	19439605
Pubmed	NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.	NMNAT1 NMNAT3	1.64e-06	2	45	2	18344983
Pubmed	Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress.	HSP90B1 EIF2AK3	4.91e-06	3	45	2	11907036
Pubmed	Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a.	SYTL4 SYTL2	4.91e-06	3	45	2	18940603
Pubmed	SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration.	NMNAT1 NMNAT3	4.91e-06	3	45	2	33107823
Pubmed	Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship.	NMNAT1 NMNAT3	4.91e-06	3	45	2	20954240
Pubmed	Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms.	NMNAT1 NMNAT3	4.91e-06	3	45	2	16118205
Pubmed	Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases.	NMNAT1 NMNAT3	4.91e-06	3	45	2	20388704
Pubmed	Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells.	NMNAT1 NMNAT3	4.91e-06	3	45	2	20457531
Pubmed	Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis.	NMNAT1 NMNAT3	4.91e-06	3	45	2	17402747
Pubmed	Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.	SYTL4 SYTL2	9.81e-06	4	45	2	18266782
Pubmed	Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: identification of the Slp homology domain.	SYTL4 SYTL2	9.81e-06	4	45	2	11327731
Pubmed	Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo.	NMNAT1 NMNAT3	9.81e-06	4	45	2	23082226
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	WDR3 HSP90B1 ERCC3 DST NMNAT1 TERF2	1.43e-05	410	45	6	26949251
Pubmed	HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.	EIF2AK3 RYR1	2.45e-05	6	45	2	19009018
Pubmed	Rescue of peripheral and CNS axon defects in mice lacking NMNAT2.	NMNAT1 NMNAT3	2.45e-05	6	45	2	23946398
Pubmed	Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins.	SYTL4 SYTL2	2.45e-05	6	45	2	11243866
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	WDR3 MYOF HSP90B1 ERCC3 DST NMNAT1 NUDC SPTBN2 METTL14	2.80e-05	1257	45	9	36526897
Pubmed	E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.	PYGM DST SLC4A4 SPTBN2	2.86e-05	135	45	4	29859926
Pubmed	Roles of Nmnat1 in the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via histone acetylation.	NMNAT1 NMNAT3	3.42e-05	7	45	2	30166529
Pubmed	A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport.	SYTL4 SYTL2	3.42e-05	7	45	2	11980908
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	WDR3 DDX23 CD74 MYOF HSP90B1 BZW1 DST NUDC SPTBN2	8.03e-05	1440	45	9	30833792
Pubmed	Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.	KALRN SPTBN2	8.94e-05	11	45	2	17607528
Pubmed	Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene).	SLC4A5 SPTBN2	1.07e-04	12	45	2	21705333
Pubmed	The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins.	EID3 TERF2	1.27e-04	13	45	2	17589526
Pubmed	Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.	WDR3 HSP90B1 ERCC3 NMNAT1	1.47e-04	206	45	4	22174317
Pubmed	Enzymology of NAD+ homeostasis in man.	NMNAT1 NMNAT3	1.47e-04	14	45	2	14704851
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH17 DNAH1	1.47e-04	14	45	2	9373155
Pubmed	Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins.	HSP90B1 EIF2AK3	1.70e-04	15	45	2	17090218
Pubmed	Functional characterization of core promoter elements: DPE-specific transcription requires the protein kinase CK2 and the PC4 coactivator.	ERCC3 TERF2	1.70e-04	15	45	2	15893730
Pubmed	The endoplasmic reticulum stress response in aging and age-related diseases.	HSP90B1 EIF2AK3	1.70e-04	15	45	2	22934019
Pubmed	Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.	SYTL4 SYTL2	1.94e-04	16	45	2	12590134
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	WDR3 DDX23 MYOF ERCC3 DST NMNAT1	1.98e-04	660	45	6	32780723
Pubmed	Pharmacologic Suppression of B7-H4 Glycosylation Restores Antitumor Immunity in Immune-Cold Breast Cancers.	NGLY1 EIF2AK3	2.20e-04	17	45	2	32938586
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	MYOF HSP90B1 SPTBN2	2.35e-04	92	45	3	37343697
Pubmed	Genetic mapping of five mouse genes encoding synaptotagmins.	CD74 HSP90B1	2.76e-04	19	45	2	8747928
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	DST DNAH17	3.06e-04	20	45	2	21689717
Pubmed	Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.	DDX23 SPTBN2 DNAH1	3.18e-04	102	45	3	21926972
Pubmed	Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.	DDX23 EML2 HSP90B1 NUDC NMNAT3	3.26e-04	464	45	5	32457219
Pubmed	A human MAP kinase interactome.	HSP90B1 POGZ DST SLC4A4 SPTBN2	4.02e-04	486	45	5	20936779
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	CD74 NMNAT1 SPTBN2 DNAH1 USP40	4.41e-04	496	45	5	31343991
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	KIAA0408 PYGM DST KALRN RYR1	4.45e-04	497	45	5	23414517
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DDX23 HSP90B1 POGZ ERCC3 DST KALRN SPTBN2	4.47e-04	1082	45	7	38697112
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	POGZ NGLY1 TERF2	4.99e-04	119	45	3	23508102
Pubmed	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.	KIAA0408 PYGM POGZ ERCC3 NGLY1 GNMT NMNAT1 SYTL4	5.50e-04	1477	45	8	31515488
Pubmed	Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.	CD74 USP40	5.63e-04	27	45	2	34709416
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	MYOF HSP90B1 BZW1 DST RYR1 DNAH1	5.77e-04	807	45	6	30575818
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	DDX23 POGZ ERCC3 TERF2 METTL14	6.11e-04	533	45	5	30554943
Pubmed	Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.	KALRN RYR1	6.96e-04	30	45	2	20080650
Pubmed	The unfolded protein response: integrating stress signals through the stress sensor IRE1α.	HSP90B1 EIF2AK3	7.43e-04	31	45	2	22013210
Pubmed	Gene expression in the developing mouse retina by EST sequencing and microarray analysis.	DST SLC4A5 METTL14	8.34e-04	142	45	3	11812828
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	DDX23 MYOF DST NMNAT1	8.63e-04	329	45	4	34316702
Pubmed	Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.	DDX23 GNMT TERF2 NUDC	8.73e-04	330	45	4	21044950
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	WDR3 DDX23 MYOF TERF2	9.75e-04	340	45	4	24332808
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	KIAA0408 DST KALRN	9.96e-04	151	45	3	17043677
Pubmed	ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.	ERCC3 TERF2	1.12e-03	38	45	2	30629181
Pubmed	Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.	FANCL NGLY1 BZW1 EIF2AK3	1.19e-03	359	45	4	35559673
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	WDR3 CD74 HSP90B1 POGZ DST KALRN SPTBN2	1.23e-03	1285	45	7	35914814
Pubmed	DDI2 protease controls embryonic development and inflammation via TCF11/NRF1.	NGLY1 EIF2AK3	1.24e-03	40	45	2	39328932
Interaction	GOLGA6L6 interactions	GOLGA6L6 GOLGA6L2	1.27e-05	3	42	2	int:GOLGA6L6
Cytoband	15q11.2	GOLGA6L6 GOLGA6L2 GOLGA6L1 GOLGA6L22	2.51e-05	172	45	4	15q11.2
Cytoband	11q14	PRCP SYTL2	6.16e-05	12	45	2	11q14
Cytoband	Ensembl 112 genes in cytogenetic band chr15q11	GOLGA6L6 GOLGA6L2 GOLGA6L1 GOLGA6L22	6.21e-05	217	45	4	chr15q11
GeneFamily	Synaptotagmin like tandem C2 proteins	SYTL4 SYTL2	1.27e-04	10	31	2	822
GeneFamily	Dyneins, axonemal	DNAH17 DNAH1	3.81e-04	17	31	2	536
GeneFamily	Fibronectin type III domain containing	IL31RA KALRN ANKFN1	2.55e-03	160	31	3	555
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	REM1 SYTL4 RYR1 DNAH17	1.91e-06	88	45	4	b4620e79ea80681305434707e87cb02a7c6a5e4f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	REM1 SYTL4 RYR1 DNAH17	1.91e-06	88	45	4	7992f8e621edf464bffcb70a6cc5f3b60c1d96f8
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	REM1 SYTL4 RYR1 DNAH17	1.91e-06	88	45	4	b7b55f51af8ffa82813a4747580985a430da9ed1
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AK7 RYR1 SPTBN2 DNAH1	2.00e-05	159	45	4	00a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	DPYS SLC4A4 NUDC SYTL2	2.97e-05	176	45	4	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 SLC4A4 KALRN DNAH1	3.54e-05	184	45	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 SLC4A4 KALRN DNAH1	3.54e-05	184	45	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	10x5'-blood-Myeloid_Dendritic-DC1\|blood / Manually curated celltypes from each tissue	CD74 PRCP RYR1 USP40	3.54e-05	184	45	4	09fa465d1852b9b7e0405c27d4e5de276c9ba871
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 SLC4A4 KALRN DNAH1	3.54e-05	184	45	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOF REM1 SLC4A4 SYTL2	3.54e-05	184	45	4	102b6f621a5b551e622f97b12d787c080b052a72
ToppCell	COVID_vent-Myeloid-Dendritic-cDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CD74 MYOF DST PRCP	3.69e-05	186	45	4	39457a7b43537f2c3e221f9375c95d4515424d7d
ToppCell	COVID_vent-Myeloid-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CD74 MYOF DST PRCP	3.69e-05	186	45	4	63a5cdd3f60681762a218be32db84be8f29b88fd
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD74 ANKFN1 SPTBN2 SYTL2	4.35e-05	194	45	4	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	COVID-19_Severe-cDC\|COVID-19_Severe / disease group, cell group and cell class	CD74 DST PRCP RYR1	4.44e-05	195	45	4	6419090b19de7b5d5140eaecf231860273da2c0d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD74 ANKFN1 SPTBN2 SYTL2	4.44e-05	195	45	4	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	healthy_donor-Myeloid-Dendritic-cDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	CD74 MYOF DST PRCP	4.53e-05	196	45	4	aac79fc45cab4a16e2fa02652ece0999591261a5
ToppCell	healthy_donor-Myeloid-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	CD74 MYOF DST PRCP	4.53e-05	196	45	4	ea590b8ea3d13ff93cb5863a44936b0cfdf3b868
ToppCell	VE-mDC2-\|VE / Condition, Cell_class and T cell subcluster	CD74 MYOF DST PRCP	4.62e-05	197	45	4	6629588819ec31a7e4f33b94b8c035145a5f6c17
ToppCell	Healthy/Control-cDC\|World / Disease group and Cell class	CD74 DST PRCP RYR1	4.62e-05	197	45	4	4497d4073f4d3e74de907325fba9eb4af5766bf4
ToppCell	COVID-19_Severe-Myeloid-cDC\|COVID-19_Severe / Disease group, lineage and cell class	CD74 MYOF DST PRCP	4.62e-05	197	45	4	843b0f1cc26864ee635df7938c77552ee06fe00b
ToppCell	VE-mDC2\|VE / Condition, Cell_class and T cell subcluster	CD74 MYOF DST PRCP	4.62e-05	197	45	4	e3172102ad17c92c3038cad37bf933eb04351048
ToppCell	Healthy-cDC\|World / disease group, cell group and cell class	CD74 DST PRCP RYR1	4.71e-05	198	45	4	8976f8d26cb7ff79f74def138c4bbbb0bc2eaf00
ToppCell	COVID-19_Severe-cDC\|World / disease group, cell group and cell class	CD74 DST PRCP RYR1	4.71e-05	198	45	4	c452334249f047265ae89dcabe7de446d968cae6
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIAA0408 MYOF DST SYTL4	4.80e-05	199	45	4	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYOF DST SYTL4 NMNAT3	4.80e-05	199	45	4	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIAA0408 MYOF SLC4A4 SYTL2	4.80e-05	199	45	4	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	control-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CD74 DST PRCP RYR1	4.80e-05	199	45	4	31825ba336603fe940dea6022e18ec25af110f4c
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYOF DST SYTL4 SYTL2	4.80e-05	199	45	4	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYOF DST SYTL4 NMNAT3	4.89e-05	200	45	4	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIAA0408 DST NMNAT3 SYTL2	4.89e-05	200	45	4	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KIAA0408 MYOF SLC4A4 SYTL2	4.89e-05	200	45	4	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYOF DST SYTL4 NMNAT3	4.89e-05	200	45	4	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	KIAA0408 SLC4A4 NMNAT3 SYTL2	4.89e-05	200	45	4	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYOF DST SYTL4 NMNAT3	4.89e-05	200	45	4	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIAA0408 MYOF SLC4A4 SYTL2	4.89e-05	200	45	4	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	COVID-19-COVID-19_Severe-Myeloid-cDC\|COVID-19_Severe / Disease, condition lineage and cell class	CD74 MYOF DST PRCP	4.89e-05	200	45	4	e7b808d8ed65343a4345fafb03015fe4f7ce302f
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYOF DST SYTL4 NMNAT3	4.89e-05	200	45	4	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	severe-cDC\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CD74 MYOF DST PRCP	4.89e-05	200	45	4	26e04ea276dbca5cde48335c401269c7123b54d2
ToppCell	mild-cDC\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CD74 DST PRCP RYR1	4.89e-05	200	45	4	d6409ee5b9067be3dd2f852825e09151b5b22d7c
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	KIAA0408 MYOF SLC4A4 SYTL2	4.89e-05	200	45	4	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	KIAA0408 DST SYTL4 SYTL2	4.89e-05	200	45	4	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIAA0408 SLC4A4 NMNAT3 SYTL2	4.89e-05	200	45	4	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIAA0408 PYGM ERCC3	3.20e-04	132	45	3	46c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCell	LPS-IL1RA+antiTNF-Unknown\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIAA0408 PYGM ERCC3	3.20e-04	132	45	3	a022c3c41654166cb106f27dc54fa88e8c40f898
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERCC3 SLC4A4 PRCP	4.21e-04	145	45	3	47a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKFN1 AK7 DNAH1	4.74e-04	151	45	3	81cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKFN1 AK7 DNAH1	4.74e-04	151	45	3	9cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCell	droplet-Fat-Scat-21m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	4.74e-04	151	45	3	79827a76c675dcb82f59c0a45d0f962b02d5bfd6
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKFN1 AK7 DNAH1	5.02e-04	154	45	3	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKFN1 AK7 DNAH1	5.02e-04	154	45	3	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKFN1 AK7 DNAH1	5.12e-04	155	45	3	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKFN1 AK7 DNAH1	5.12e-04	155	45	3	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 MYOF RYR1	5.21e-04	156	45	3	2ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD74 DST PRCP	5.31e-04	157	45	3	e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCell	droplet-Fat-Scat-21m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	5.41e-04	158	45	3	718eafcf8a171bb69b402dc9d69564c3521a62a9
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD74 DST PRCP	5.41e-04	158	45	3	e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCell	droplet-Fat-Scat-21m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	5.41e-04	158	45	3	c8df636412a08c570f235c34d4cff46924a9b11d
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CD74 MYOF GNMT	5.51e-04	159	45	3	a4bfd59c53237964fc24a24de5c1925fdd01db99
ToppCell	droplet-Lung-nan-21m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR3 POGZ NMNAT1	5.61e-04	160	45	3	4738d0c73d8c3508e5b5beb6c61e0ad551d9b949
ToppCell	droplet-Lung-nan-21m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR3 POGZ NMNAT1	5.61e-04	160	45	3	0b8151037b28f52a21918856a1e9336e8d5edb90
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 MYOF RYR1	5.61e-04	160	45	3	1f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	5.72e-04	161	45	3	3db97af49520dc8cbafb4454d8afd9d588160e89
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	5.72e-04	161	45	3	f1d258c81bcf0f3c52bd20aa58faa9a5fd888168
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	5.72e-04	161	45	3	787f91f906756ef570c0d02936c3cdfafb3f7454
ToppCell	facs-MAT-Fat-3m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.03e-04	164	45	3	1250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCell	facs-MAT-Fat-3m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.03e-04	164	45	3	b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCell	facs-MAT-Fat-3m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.03e-04	164	45	3	fa0d77b648cde5e42b9394e877168c80de238bde
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DPYS SLC4A4 SPTBN2	6.25e-04	166	45	3	4d63c758d46e73311b864148c646bf081498dee7
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DPYS SLC4A4 SPTBN2	6.25e-04	166	45	3	4160ccf9291072a6e2782f9ad141bc9a9747f3ad
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 MYOF DPYS	6.25e-04	166	45	3	91eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 MYOF DST	6.25e-04	166	45	3	b3d9b61847c6c96b8cb28b8a6aeda52f43c706ab
ToppCell	ICU-NoSEP-Myeloid-cDC2\|ICU-NoSEP / Disease, Lineage and Cell Type	CD74 DST PRCP	6.36e-04	167	45	3	5b7b731944d888591279ef6167b3ae8cab3f6886
ToppCell	facs-MAT-Fat-18m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.36e-04	167	45	3	c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD74 DPYS RYR1	6.36e-04	167	45	3	fd84a99ea142d1684cdcf4a88ef1d541760bc78a
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 DST SLC4A4	6.47e-04	168	45	3	04a7810f95196a21325356b42084f96c11af5964
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPYS SLC4A4 SPTBN2	6.47e-04	168	45	3	e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPYS SLC4A4 SPTBN2	6.47e-04	168	45	3	403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D175\|Adult / Lineage, Cell type, age group and donor	DPYS KALRN PRCP	6.58e-04	169	45	3	e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell	facs-GAT-Fat-18m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.58e-04	169	45	3	0e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCell	facs-GAT-Fat-18m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.58e-04	169	45	3	9bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCell	facs-GAT-Fat-18m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.58e-04	169	45	3	7a7416fcbffcf57d19b477d9da091e04e3499524
ToppCell	droplet-Lung-nan-21m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.69e-04	170	45	3	71c52fadecc6b4bfe98692b266adaa1406f6d56d
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD74 PRCP RYR1	6.81e-04	171	45	3	87cb65648c663e246f94cea1a5ed12e8e29ec629
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC4A4 GNMT EID3	6.92e-04	172	45	3	5401ac7739f95fb8681cfb4747ab6e447a3c2ae8
ToppCell	droplet-Trachea-nan-3m-Myeloid-macrophage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.92e-04	172	45	3	f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.92e-04	172	45	3	0c0ae2da3cba6022403434567800f16e61a34a2b
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC4A4 GNMT EID3	6.92e-04	172	45	3	b3da7f488d191214d7bb74fbac189fe8c29ee6cd
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYOF DST RYR1	6.92e-04	172	45	3	e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.92e-04	172	45	3	d80c207f3489be2da2f40f47a7835cb73c949c3e
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD74 PRCP RYR1	6.92e-04	172	45	3	6b01448443cf8392ed8248ff452b80c31240b85d
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD74 PRCP RYR1	6.92e-04	172	45	3	f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCell	facs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD74 PRCP RYR1	6.92e-04	172	45	3	eaba10a4d4eaab42ad2e2da65ebb20b50edaf815
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC4A4 GNMT EID3	6.92e-04	172	45	3	74dd4a7acb2cf857fed20219e4d7dc1adfbaa398
ToppCell	TCGA-Brain-Primary_Tumor\|TCGA-Brain / Sample_Type by Project: Shred V9	SLC4A4 SYTL4 ANKFN1	7.04e-04	173	45	3	f6ba22661e67c17d49d1058d4170ba8f36bf47f0
ToppCell	facs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD74 PRCP RYR1	7.16e-04	174	45	3	c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ANKFN1 AK7 DNAH1	7.16e-04	174	45	3	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	droplet-Marrow-nan-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXT2 IL31RA DNAH1	7.16e-04	174	45	3	55cc8300489d11322724159ec7d0e1d32a702e91
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ANKFN1 AK7 DNAH1	7.28e-04	175	45	3	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	PYGM MYOF SLC4A5	7.40e-04	176	45	3	8e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	HSP90B1 DST KALRN	7.40e-04	176	45	3	3de0c7d77210049e5616db21eed1490a17a5ec2d
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSP90B1 DST SYTL2	2.56e-04	50	27	3	GAVISH_3CA_METAPROGRAM_EPITHELIAL_COLON_RELATED
Drug	Deamido-Nad+	NMNAT1 NMNAT3	3.48e-06	2	43	2	DB04099
Drug	NaMN	NMNAT1 EIF2AK3 RYR1 NMNAT3	9.23e-06	70	43	4	CID000000941
Drug	Nicotinamide Mononucleotide	NMNAT1 NMNAT3	1.04e-05	3	43	2	DB03227
Disease	anemia (implicated_via_orthology)	SLC4A4 SLC4A5	1.77e-04	15	39	2	DOID:2355 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
WQEKMDEIWLKDEST	EIF2AK3	666	Q9NZJ5
VWSSVMSTVEWNKKE	BZW1	296	Q7L1Q6
VWKMESIFRKVETDW	NGLY1	521	Q96IV0
WSDWSQEKMGMTEEE	IL31RA	211	Q8NI17
EAWSKLMEWLEESEK	DST	6711	Q03001
WTWDDIMKLEIDEIA	METTL14	211	Q9HCE5
TWWSDQVKEEMKILV	DPYS	136	Q14117
WKAIEKEATSWMVKA	EID3	151	Q8N140
KELWTWMEDLQKEML	KALRN	651	O60229
KDWISETWVNLAMVD	PRCP	276	P42785
QWENTETNWHKEKME	KIAA0408	6	Q6ZU52
EWESQWKIMQKKIEE	KIAA0408	31	Q6ZU52
KMWRQEEKIQEWEEK	GOLGA6L1	301	Q8N7Z2
WEQEKMQEQEEKIWE	GOLGA6L2	501	Q8N9W4
WREEEKMHEQEKIWE	GOLGA6L6	521	A8MZA4
KMWRQEEKIQEWEEK	GOLGA6L22	251	H0YM25
WREEEKMHEQEKIWE	GOLGA6L22	496	H0YM25
WVIEEANWMTLDKDV	GNMT	111	Q14749
HWSQKKLDEMTDRDW	DDX23	356	Q9BUQ8
VEKTVWDWELMNDIK	HSP90B1	326	P14625
EEYKQVAWVKWMDSS	DNAH1	2171	Q9P2D7
WKTTKWKDINVEQMD	DNAH17	1296	Q9UFH2
NVEEIPENDSWKEMW	FUT11	436	Q495W5
MLSVWDWAKETKVVD	EML2	186	O95834
WEAERVMEWLKTQEW	ERCC3	421	P19447
NTMETIDWKVFESWM	CD74	171	P04233
ESLKAMIAWEWTIEK	RYR1	2811	P21817
VVVDTWEAEKLDKSW	REM1	131	O75628
WMDSTSEEVALWEKM	SYTL2	896	Q9HCH5
DWMDSTGEEVSLWQK	SYTL4	631	Q96C24
VLHFIEWTKWSQEKM	SLC9B1P1	116	A6NJY1
WDVMDEIDEKTWVLE	FANCL	201	Q9NW38
DDEIMELWSTRVWQK	POGZ	1201	Q7Z3K3
VTVHLEKINKMEWWS	NUDC	241	Q9Y266
EEWEWIQKLSGSESM	ANKFN1	651	Q8N957
DLERMDWDKAWDVTV	PYGM	356	P11217
QETAEKWQEKMDWLQ	SPTBN2	1996	O15020
EMNKWKYESEWTNEV	EXT2	576	Q93063
QMEWKESARWIKFEE	SLC4A5	126	Q9BY07
QEMEWKETARWIKFE	SLC4A4	121	Q9Y6R1
TSGKDTMVKWWDLDT	WDR3	166	Q9UNX4
TKEEKWVTSMNEIDW	USP40	736	Q9NVE5
ITKKQKWTVEESEWV	TERF2	486	Q15554
VEMAEKIARWEEWNK	AK7	646	Q96M32
SKLTEKEEEIVDWWS	MYOF	1441	Q9NZM1
EVDTWESLQKEWKET	NMNAT1	81	Q9HAN9
DPWESEQAQWMETVK	NMNAT3	81	Q96T66