Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSH3 domain binding

SGIP1 WIPF1 SYNJ1 MAP4K3 ADAM15 INPPL1 SHANK3

2.95e-07143627GO:0017124
GeneOntologyMolecularFunctionactin binding

WASL WIPF1 INPPL1 RUSC1 ANTXR1 COBL LMOD1 WIPF2 SHANK3 FMNL1

2.02e-064796210GO:0003779
GeneOntologyMolecularFunctionprotein domain specific binding

SCAF1 WBP11 SGIP1 WIPF1 SYNJ1 MAP4K3 ADAM15 PIK3R1 INPPL1 CASKIN1 TAMALIN SHANK3

1.33e-058756212GO:0019904
GeneOntologyMolecularFunctioncytoskeletal protein binding

CCSAP WASL SGIP1 WIPF1 INPPL1 RUSC1 ANTXR1 COBL LMOD1 WIPF2 SHANK3 FMNL1

1.22e-0410996212GO:0008092
GeneOntologyMolecularFunctionprofilin binding

WIPF1 FMNL1

7.24e-0413622GO:0005522
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 5-phosphatase activity

SYNJ1 INPPL1

7.24e-0413622GO:0034595
GeneOntologyMolecularFunctioninositol trisphosphate phosphatase activity

SYNJ1 INPPL1

8.43e-0414622GO:0046030
GeneOntologyBiologicalProcessactin cytoskeleton organization

PTPN1 WASL MAGEL2 WIPF1 PIK3R1 INPPL1 DNAJB6 ANTXR1 COBL LMOD1 NAA80 SHANK3 FMNL1 FCHSD1

6.74e-088036114GO:0030036
GeneOntologyBiologicalProcessactin filament-based process

PTPN1 WASL MAGEL2 WIPF1 PIK3R1 INPPL1 DNAJB6 ANTXR1 COBL LMOD1 NAA80 SHANK3 FMNL1 FCHSD1

3.20e-079126114GO:0030029
GeneOntologyBiologicalProcessactin filament organization

WASL MAGEL2 WIPF1 PIK3R1 INPPL1 COBL LMOD1 NAA80 SHANK3 FCHSD1

2.24e-065096110GO:0007015
GeneOntologyBiologicalProcesssupramolecular fiber organization

CCSAP WASL MAGEL2 WIPF1 PIK3R1 INPPL1 DNAJB6 COBL LMOD1 NAA80 SHANK3 FOXC1 FCHSD1

3.52e-069576113GO:0097435
GeneOntologyBiologicalProcessactin polymerization or depolymerization

WASL WIPF1 COBL LMOD1 NAA80 FCHSD1

4.92e-05222616GO:0008154
GeneOntologyBiologicalProcesspostsynaptic density assembly

LRFN4 CASKIN1 SHANK3

1.38e-0434613GO:0097107
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

CCSAP WASL LRFN4 PIK3R1 CASKIN1 INSM1 DNAJB6 ANTXR1 COBL LMOD1 SHANK3 FCHSD1

1.60e-0411896112GO:0044087
DomainWH2

WASL WIPF1 COBL LMOD1 WIPF2

6.15e-1014615SM00246
DomainWH2

WASL WIPF1 COBL LMOD1 WIPF2

1.34e-0916615PF02205
DomainWH2_dom

WASL WIPF1 COBL LMOD1 WIPF2

6.14e-0921615IPR003124
DomainWH2

WASL WIPF1 COBL LMOD1 WIPF2

1.27e-0824615PS51082
DomainSH3

PIK3R1 CASKIN1 RUSC1 PPP1R13L SHANK3 FCHSD1

7.29e-05216616SM00326
DomainSH3

PIK3R1 CASKIN1 RUSC1 PPP1R13L SHANK3 FCHSD1

7.29e-05216616PS50002
DomainSH3_domain

PIK3R1 CASKIN1 RUSC1 PPP1R13L SHANK3 FCHSD1

8.07e-05220616IPR001452
DomainNUT

NUTM2F NUTM2G

1.04e-045612IPR024310
DomainNUT_N

NUTM2F NUTM2G

1.04e-045612IPR024309
DomainNUT

NUTM2F NUTM2G

1.04e-045612PF12881
DomainSH3_2

PIK3R1 CASKIN1 SHANK3 FCHSD1

1.79e-0486614IPR011511
DomainSH3_2

PIK3R1 CASKIN1 SHANK3 FCHSD1

1.79e-0486614PF07653
DomainIPPc

SYNJ1 INPPL1

4.64e-0410612IPR000300
DomainIPPc

SYNJ1 INPPL1

4.64e-0410612SM00128
DomainSAM_1

INPPL1 CASKIN1 SHANK3

1.43e-0368613PF00536
DomainSH3_1

PIK3R1 RUSC1 PPP1R13L FCHSD1

2.03e-03164614PF00018
DomainSH3_9

RUSC1 PPP1R13L FCHSD1

2.12e-0378613PF14604
DomainSAM

INPPL1 CASKIN1 SHANK3

2.99e-0388613SM00454
Domain-

SYNJ1 INPPL1

3.24e-03266123.60.10.10
DomainExo_endo_phos

SYNJ1 INPPL1

3.24e-0326612PF03372
DomainEndo/exonuclease/phosphatase

SYNJ1 INPPL1

3.49e-0327612IPR005135
DomainSAM_DOMAIN

INPPL1 CASKIN1 SHANK3

3.71e-0395613PS50105
DomainSAM

INPPL1 CASKIN1 SHANK3

3.93e-0397613IPR001660
DomainHMGI/Y_DNA-bd_CS

PRB3 PRB4

4.59e-0331612IPR000637
Domain-

INPPL1 CASKIN1 SHANK3

5.04e-031066131.10.150.50
DomainAnk_2

ACAP1 CASKIN1 PPP1R13L SHANK3

5.34e-03215614PF12796
DomainSAM/pointed

INPPL1 CASKIN1 SHANK3

6.62e-03117613IPR013761
DomainCYSTEINE_SWITCH

ADAM15 MMP15

7.93e-0341612PS00546
DomainPept_M10_metallopeptidase

ADAM15 MMP15

8.69e-0343612IPR001818
Domain-

ACAP1 CASKIN1 PPP1R13L SHANK3

8.76e-032486141.25.40.20
DomainANK

ACAP1 CASKIN1 PPP1R13L SHANK3

9.13e-03251614SM00248
DomainANK_REPEAT

ACAP1 CASKIN1 PPP1R13L SHANK3

9.38e-03253614PS50088
DomainAnkyrin_rpt-contain_dom

ACAP1 CASKIN1 PPP1R13L SHANK3

9.51e-03254614IPR020683
DomainANK_REP_REGION

ACAP1 CASKIN1 PPP1R13L SHANK3

9.51e-03254614PS50297
PathwaySIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES

PTPN1 PIK3R1 INPPL1 SOS2

1.85e-0551444M7955
PathwayKEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TO_ACTIN_SIGNALING_PATHWAY

WASL WIPF1 WIPF2

1.87e-0517443M47728
PathwayREACTOME_RAC1_GTPASE_CYCLE

WASL WIPF1 PIK3R1 WIPF2 FMNL1 SOS2

2.13e-05184446M41809
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY

WASL WIPF1 WIPF2

3.63e-0521443M47722
PathwayPID_MET_PATHWAY

PTPN1 WASL PIK3R1 INPPL1

1.05e-0479444M48
PathwayREACTOME_CDC42_GTPASE_CYCLE

WASL WIPF1 PIK3R1 WIPF2 FMNL1

1.16e-04155445M41808
PathwayWP_INSULIN_SIGNALING

PTPN1 MAP4K3 PIK3R1 INPPL1 SOS2

1.34e-04160445MM15956
PathwayWP_INSULIN_SIGNALING

PTPN1 MAP4K3 PIK3R1 INPPL1 SOS2

1.34e-04160445M39482
PathwayPID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY

PTPN1 WASL PIK3R1

1.73e-0435443M127
PathwayREACTOME_INTERLEUKIN_2_FAMILY_SIGNALING

PIK3R1 INPPL1 SOS2

1.73e-0435443MM15144
PathwayREACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES

WASL WIPF1 WIPF2

1.89e-0436443M27549
PathwayBIOCARTA_CDC42RAC_PATHWAY

WASL PIK3R1

1.98e-047442MM1487
PathwayPID_EPHB_FWD_PATHWAY

WASL SYNJ1 PIK3R1

2.59e-0440443M62
PathwayBIOCARTA_CDC42RAC_PATHWAY

WASL PIK3R1

2.63e-048442M5291
PathwayREACTOME_INTERLEUKIN_2_FAMILY_SIGNALING

PIK3R1 INPPL1 SOS2

3.44e-0444443M1012
PathwaySIG_CHEMOTAXIS

WASL PIK3R1 INPPL1

3.67e-0445443M5193
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE

SYNJ1 PIK3R1 INPPL1

5.02e-0450443MM14641
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE

SYNJ1 PIK3R1 INPPL1

5.96e-0453443M662
PathwayREACTOME_RHOJ_GTPASE_CYCLE

WASL PIK3R1 WIPF2

6.65e-0455443M41815
PathwayWP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY

PTPN1 MAP4K3 PIK3R1 SOS2

7.46e-04132444M39338
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

WASL WIPF1 PIK3R1 WIPF2

1.01e-03143444M27107
PathwaySIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES

PTPN1 INPPL1 SOS2

1.18e-0367443M295
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

WASL WIPF1 SYNJ1 MAP4K3 PIK3R1 INPPL1 WIPF2 SOS2

1.33e-1110362821706016
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

WASL WIPF1 SYNJ1 INPPL1 WIPF2 PRRC2A

4.16e-0810862619531213
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

WASL WIPF1 PIK3R1 WIPF2 FCHSD1 SOS2

4.90e-0811162622558309
Pubmed

Enteropathogenic Escherichia coli and vaccinia virus do not require the family of WASP-interacting proteins for pathogen-induced actin assembly.

WASL WIPF1 WIPF2

5.38e-08562322966049
Pubmed

WW domains provide a platform for the assembly of multiprotein networks.

WASL WBP11 WIPF1 WIPF2 FMNL1 SF3B2

3.42e-0715462616055720
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

ACAP1 WASL WIPF1 MAP4K3 PIK3R1 SHANK3 SOS2

2.00e-0632962717474147
Pubmed

CIN85 interacting proteins in B cells-specific role for SHIP-1.

WASL WIPF1 PIK3R1 INPPL1

2.71e-065462421725061
Pubmed

WIP and WICH/WIRE co-ordinately control invadopodium formation and maturation in human breast cancer cell invasion.

WIPF1 WIPF2

3.13e-06262227009365
Pubmed

A critical function for the actin cytoskeleton in targeted exocytosis of prefusion vesicles during myoblast fusion.

WASL WIPF1

3.13e-06262217419995
Pubmed

Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome.

WASL WIPF1

3.13e-06262212437929
Pubmed

Identification of Lys-Pro-Gln as a novel cleavage site specificity of saliva-associated proteases.

PRB3 PRB4

3.13e-06262218463091
Pubmed

Invadopodia proteins, cortactin, N-WASP and WIP differentially promote local invasiveness in ameloblastoma.

WASL WIPF1

3.13e-06262226752341
Pubmed

A pharmacogenomic approach to the treatment of children with GH deficiency or Turner syndrome.

PTPN1 SOS2

3.13e-06262223761422
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

WASL WBP11 PIK3R1 INPPL1 DNAJB6 COBL PPP1R13L WIPF2 PRRC2A SOS2

4.76e-06916621032203420
Pubmed

The WH1 and EVH1 domains of WASP and Ena/VASP family members bind distinct sequence motifs.

WASL WIPF1

9.37e-06362212372256
Pubmed

Molecular genetics of human salivary proteins and their polymorphisms.

PRB3 PRB4

9.37e-0636223055850
Pubmed

Waltzing with WASP.

WASL WIPF1

9.37e-06362210087612
Pubmed

WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization.

WASL WIPF1

9.37e-06362223707428
Pubmed

Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons.

HCN1 SHANK3

1.87e-05462226966193
Pubmed

cDNA clones for mouse parotid proline-rich proteins. mRNA regulation by isoprenaline and the nucleotide sequence of proline-rich protein cDNA MP5.

PRB3 PRB4

1.87e-0546221339347
Pubmed

Finding new posttranslational modifications in salivary proline-rich proteins.

PRB3 PRB4

1.87e-05462220879038
Pubmed

WIP regulates N-WASP-mediated actin polymerization and filopodium formation.

WASL WIPF1

1.87e-05462211331876
Pubmed

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin.

WASL WIPF1

1.87e-05462215684033
Pubmed

The involvement of proline-rich protein Mus musculus predicted gene 4736 in ocular surface functions.

PRB3 PRB4

1.87e-05462227588265
Pubmed

Length polymorphisms in human proline-rich protein genes generated by intragenic unequal crossing over.

PRB3 PRB4

1.87e-0546222851479
Pubmed

A human MAP kinase interactome.

WASL WIPF1 MAP4K3 PIK3R1 COBL WIPF2 SOS2

2.52e-0548662720936779
Pubmed

A nuclear SH3 domain-binding protein that colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks.

WBP11 PIK3R1

3.12e-05562211375989
Pubmed

Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor.

PTPN1 PIK3R1

3.12e-05562218449947
Pubmed

PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase.

PIK3R1 INPPL1

3.12e-05562219501627
Pubmed

WIP modulates dendritic spine actin cytoskeleton by transcriptional control of lipid metabolic enzymes.

WASL WIPF1

3.12e-05562224698977
Pubmed

The intriguing heterogeneity of human salivary proline-rich proteins: Short title: Salivary proline-rich protein species.

PRB3 PRB4

3.12e-05562226375204
Pubmed

FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.

WASL FCHSD1

3.12e-05562223437151
Pubmed

Wiskott-Aldrich syndrome protein is involved in alphaIIb beta3-mediated cell adhesion.

WASL WIPF1

4.67e-05662216582881
Pubmed

The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading.

PIK3R1 INPPL1

4.67e-05662215735664
Pubmed

Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system.

PRB3 PRB4

4.67e-0566222993301
Pubmed

Interaction of constitutive photomorphogenesis 1 protein with protein-tyrosine phosphatase 1B suppresses protein-tyrosine phosphatase 1B activity and enhances insulin signaling.

PTPN1 PIK3R1

4.67e-05662223439647
Pubmed

All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.

WASL SYNJ1

4.67e-05662211082044
Pubmed

Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.

WASL INPPL1 WIPF2 PRRC2A SF3B2

4.67e-0522062524550385
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CBLL1 WBP11 SGIP1 SYNJ1 HCN1 KIAA1217 CASKIN1 PRRC2A SHANK3

5.02e-0596362928671696
Pubmed

GRID: a novel Grb-2-related adapter protein that interacts with the activated T cell costimulatory receptor CD28.

PIK3R1 SOS2

6.53e-05762210820259
Pubmed

Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models.

HCN1 SHANK3

6.53e-05762231398341
Pubmed

Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein.

PTPN1 PIK3R1

6.53e-05762210660596
Pubmed

A genome-wide association study of early menopause and the combined impact of identified variants.

SGIP1 PRRC2A

6.53e-05762223307926
Pubmed

Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain.

SYNJ1 INPPL1

8.69e-05862220622009
Pubmed

Alternative splicing affecting the SH3A domain controls the binding properties of intersectin 1 in neurons.

WASL SYNJ1

1.12e-04962218539136
Pubmed

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.

PIK3R1 INPPL1

1.12e-04962210871282
Pubmed

A novel pro-Arg motif recognized by WW domains.

WBP11 PRRC2A

1.39e-041062210744724
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SCAF1 SYNJ1 SPEG INPPL1 CASKIN1 MLLT1 COBL ZFPM1 FBXL19

1.43e-04110562935748872
Pubmed

Basic molecular fingerprinting of immature cerebellar cortical inhibitory interneurons and their precursors.

SKOR1 NANOS1

1.70e-041162219141316
Pubmed

Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.

TAF3 SGIP1 PRRC2A

1.89e-046262317975119
Pubmed

Gene variants associated with ischemic stroke: the cardiovascular health study.

TAF3 SGIP1 PRRC2A

1.98e-046362319023099
Pubmed

Molecular markers of cardiac endocardial cushion development.

ZFPM1 FOXC1

2.41e-041362214648841
Pubmed

Bioinformatics and cellular signaling.

WIPF1 PIK3R1 DNAJB6 SOS2

3.19e-0418262415102471
Pubmed

PDZ-Containing Proteins Targeted by the ACE2 Receptor.

TAMALIN SHANK3

3.23e-041562234835087
Pubmed

Identification of Genes With Enriched Expression in Early Developing Mouse Cone Photoreceptors.

PIK3R1 DOC2B

3.23e-041562231260032
Pubmed

A new role for FBP21 as regulator of Brr2 helicase activity.

WBP11 SF3B2

3.69e-041662228838205
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

SGIP1 SYNJ1 HCN1 CASKIN1 PRRC2A

3.90e-0434762517114649
Pubmed

The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization.

PIK3R1 INPPL1 SOS2

4.17e-048162320697350
Pubmed

Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.

WASL WIPF2

4.18e-041762214506234
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WASL WBP11 SYNJ1 PIK3R1 HCN1 PCSK6 PRRC2A SF3B2 SOS2

4.34e-04128562935914814
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SCAF1 VSTM2L PPP1R13L PRRC2A FMNL1

4.67e-0436162526167880
Pubmed

NANOS2 promotes male germ cell development independent of meiosis suppression.

PRB3 PRB4

4.70e-041862224183939
Pubmed

Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

PIK3R1 SOS2

4.70e-041862219531499
Pubmed

ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.

SYNJ1 HCN1 CASKIN1 SHANK3

4.73e-0420262433601422
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

MLLT1 COBL ZCCHC2 PPP1R13L SHANK3 SF3B2

4.86e-0456062621653829
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

PTPN1 SYNJ1 KIAA1217 INPPL1 PPP1R13L WIPF2

5.09e-0456562625468996
Pubmed

Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.

PIK3R1 SOS2

5.24e-041962231959764
Pubmed

Glycosaminoglycan-dependent restriction of FGF diffusion is necessary for lacrimal gland development.

NDST2 FOXC1

5.82e-042062222745308
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

PTPN1 PIK3R1 SOS2

6.44e-049462332062451
Pubmed

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.

RNF31 DNAJB6 MMP15

6.85e-049662334599178
Pubmed

FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation.

KIAA1217 FOXC1

7.72e-042362219668217
Pubmed

The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.

INSM1 SKOR1

7.72e-042362223648511
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

SGIP1 SPEG CASKIN1 PRRC2A

7.82e-0423162416452087
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SCAF1 TAF3 RNF31 PIK3R1 PCSK6 DNAJB6 MLLT1 FOXC1

7.98e-04111662831753913
Pubmed

Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1.

WIPF1 PIK3R1

9.14e-042562212029088
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

MAP4K3 PIK3R1 KIAA1217 INPPL1 COBL

9.32e-0442162536976175
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

WASL SGIP1 SYNJ1 MAP4K3 KIAA1217 CASKIN1 DNAJB6 PRRC2A SHANK3

9.37e-04143162937142655
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

SYNJ1 HCN1 CASKIN1 SHANK3

1.06e-0325162427507650
Pubmed

Identification of Arx transcriptional targets in the developing basal forebrain.

MAGEL2 SKOR1

1.15e-032862218799476
Pubmed

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer.

PTPN1 ANTXR1

1.32e-033062234285210
Pubmed

Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes.

WIPF1 FCHSD1

1.41e-033162219041431
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

CBLL1 WBP11 TAF3 MLLT1 PRRC2A SF3B2 FOXC1

1.51e-0395462736373674
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

SGIP1 SYNJ1 ANTXR1

1.57e-0312862330995482
Pubmed

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

TAMALIN SHANK3

1.69e-033462230726710
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

PTPN1 SYNJ1 RUSC1 COBL

1.70e-0328562434369648
InteractionGRB2 interactions

PTPN1 ACAP1 WASL WBP11 WIPF1 SYNJ1 MAP4K3 ADAM15 PIK3R1 INPPL1 NUTM2F WIPF2 PRRC2A SHANK3 SF3B2 SOS2

1.06e-098066016int:GRB2
InteractionSORBS3 interactions

WASL LRFN4 SYNJ1 ADAM15 KIAA1217 INPPL1 FBXL19 WIPF2 SHANK3

8.12e-09202609int:SORBS3
InteractionITSN2 interactions

WASL SGIP1 WIPF1 MAP4K3 FBXL19 WIPF2 FCHSD1 SOS2

1.23e-08147608int:ITSN2
InteractionSH3RF1 interactions

ACAP1 WASL WIPF1 PRB3 MAP4K3 ADAM15 NUTM2F

3.19e-08108607int:SH3RF1
InteractionNCK1 interactions

WASL LRFN4 WIPF1 ADAM15 PIK3R1 NUTM2F WIPF2 SHANK3 SOS2

4.17e-08244609int:NCK1
InteractionNCK2 interactions

WASL WBP11 LRFN4 WIPF1 KIAA1217 FBXL19 NUTM2F WIPF2 PRRC2A

7.67e-08262609int:NCK2
InteractionPRMT2 interactions

WASL WBP11 PIK3R1 ANTXR1 PRRC2A SHANK3

2.95e-0791606int:PRMT2
InteractionSNX9 interactions

WASL SYNJ1 MAP4K3 ADAM15 PIK3R1 FCHSD1 SOS2

3.05e-07150607int:SNX9
InteractionPACSIN1 interactions

WASL WIPF1 SYNJ1 COBL SHANK3

9.51e-0760605int:PACSIN1
InteractionPFN1 interactions

WASL SYNJ1 PIK3R1 KIAA1217 INPPL1 MLLT1 NAA80 WIPF2 FMNL1 SF3B2

2.35e-065096010int:PFN1
InteractionPACSIN3 interactions

WASL WIPF1 SYNJ1 ADAM15 COBL SOS2

2.52e-06131606int:PACSIN3
InteractionSH3KBP1 interactions

WASL WIPF1 SYNJ1 PIK3R1 HCN1 INPPL1 WIPF2 PRRC2A

4.12e-06315608int:SH3KBP1
InteractionABI1 interactions

WASL PIK3R1 KIAA1217 FBXL19 WIPF2 SHANK3 SOS2

4.34e-06223607int:ABI1
InteractionSH3GL1 interactions

SYNJ1 PRB3 MAP4K3 PIK3R1 DNAJB6 NUTM2F

9.22e-06164606int:SH3GL1
InteractionITSN1 interactions

WASL WBP11 SGIP1 SYNJ1 PIK3R1 SHANK3 SOS2

1.15e-05259607int:ITSN1
InteractionWIPF3 interactions

WASL VSTM2L WIPF2

1.37e-0516603int:WIPF3
InteractionAPBB1 interactions

PTPN1 WASL WBP11 WIPF1 WIPF2 SF3B2

2.46e-05195606int:APBB1
InteractionSORBS1 interactions

SYNJ1 MAP4K3 ADAM15 INPPL1 INSM1

3.26e-05123605int:SORBS1
InteractionZCCHC2 interactions

ZCCHC2 PRRC2A SHANK3

4.26e-0523603int:ZCCHC2
InteractionSH3D19 interactions

SYNJ1 ADAM15 HCN1 SOS2

5.31e-0569604int:SH3D19
InteractionCRKL interactions

MAGEL2 WIPF1 MAP4K3 PIK3R1 SHANK3 SOS2

5.76e-05227606int:CRKL
InteractionSHANK3 interactions

WBP11 SGIP1 SYNJ1 HCN1 CASKIN1 ZCCHC2 PPP1R13L SHANK3

1.06e-04496608int:SHANK3
InteractionSH3GL2 interactions

SYNJ1 MAP4K3 ADAM15 SHANK3

1.37e-0488604int:SH3GL2
InteractionSRC interactions

CBLL1 PTPN1 WASL WBP11 ADAM15 PIK3R1 INPPL1 TAMALIN SHANK3

1.43e-04664609int:SRC
InteractionMORN4 interactions

WBP11 NUTM2F SHANK3

1.53e-0435603int:MORN4
InteractionACTC1 interactions

WASL WBP11 WIPF1 SYNJ1 COBL NAA80 NUTM2F WIPF2 SF3B2

1.99e-04694609int:ACTC1
InteractionABI2 interactions

WASL WIPF1 KIAA1217 RUSC1 FBXL19 SHANK3

2.04e-04286606int:ABI2
InteractionPACSIN2 interactions

WASL WIPF1 SYNJ1 COBL WIPF2

2.24e-04185605int:PACSIN2
InteractionTRIP10 interactions

WASL WBP11 DNAJB6 SHANK3

3.13e-04109604int:TRIP10
InteractionSORBS2 interactions

WASL SYNJ1 ADAM15 SHANK3

3.35e-04111604int:SORBS2
GeneFamilyProline rich proteins

PRB3 PRB4

7.86e-056422972
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

ZFPM1 NANOS1

6.19e-041642266
GeneFamilySterile alpha motif domain containing

INPPL1 CASKIN1 SHANK3

1.12e-0388423760
GeneFamilyAnkyrin repeat domain containing

ACAP1 CASKIN1 PPP1R13L SHANK3

2.35e-03242424403
GeneFamilyPhosphoinositide phosphatases

SYNJ1 INPPL1

2.50e-03324221079
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D122|Adult / Lineage, Cell type, age group and donor

ADAM15 ACR CASKIN1 TAMALIN SHANK3

2.93e-061606250cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

HCN1 VSTM2L SKOR1 SHANK3 FMNL1

3.62e-061676259efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

HCN1 VSTM2L SKOR1 SHANK3 FMNL1

3.62e-06167625904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8_TRM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ACAP1 WIPF1 TGFBR3L PRDM15 FMNL1

7.69e-06195625c75d04b15d9f95fe2b5650cd4a5a376776610000
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIAA1217 PCSK6 TAMALIN SHANK3 DOC2B

7.69e-06195625094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellKidney-Mesangial|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

PRB3 SPEG VSTM2L ANTXR1 LMOD1

7.89e-061966252b2cbe7f96213b7ff50442593f31820d17a2ae94
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 TAMALIN SHANK3 FOXC1 DOC2B

8.08e-06197625e8e879b7634a29569061d3515d180784094a31e7
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

ADAM15 KIAA1217 TAMALIN SHANK3 DOC2B

8.08e-06197625ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

SCAF1 INPPL1 MLLT1 FBXL19 WIPF2

8.70e-06200625ad2a6da0b1ae7a9212a3c91e5eec4baa7481d8dc
ToppCellTCGA-Bile_Duct-Primary_Tumor|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

SCAF1 INPPL1 MLLT1 FBXL19 WIPF2

8.70e-062006250350e5ffd36033099b7e32a1fdd790fff99790dc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF787 CCSAP SKOR1 ZFPM1

6.15e-0515362479c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIK3R1 SPEG ANTXR1 LMOD1

6.15e-051536241524557514668f515ac1bbe847611f564b265b42
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN1 SGIP1 ANTXR1 NUTM2F

1.03e-04175624910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN1 SGIP1 ANTXR1 NUTM2F

1.03e-04175624f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

ACR SHANK3 FOXC1 DOC2B

1.06e-04176624043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCellNS-critical-d_0-4-Myeloid-Mast_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COQ10A FAM117A NDST2 FBXL19

1.13e-041796246153e7a0eeae83e7d88f1a20093bf2113e8d66b1
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 MAP4K3 SPEG LMOD1

1.15e-04180624f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

SGIP1 SPEG ANTXR1 LMOD1

1.15e-04180624d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 MAP4K3 SPEG LMOD1

1.15e-04180624dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 SHANK3 FOXC1 DOC2B

1.20e-04182624d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCellEndothelial-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

TAMALIN SHANK3 FOXC1 DOC2B

1.28e-04185624ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 DNAJB6 TAMALIN FMNL1

1.28e-04185624e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

SGIP1 PCSK6 SHANK3 DOC2B

1.28e-041856244a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

SGIP1 PCSK6 SHANK3 DOC2B

1.28e-0418562436ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG ANTXR1 LMOD1 FOXC1

1.31e-041866244780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG ANTXR1 LMOD1 FOXC1

1.31e-04186624a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3R1 KIAA1217 ANTXR1 LMOD1

1.36e-04188624ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

SGIP1 PCSK6 SHANK3 DOC2B

1.36e-04188624c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

WIPF1 PIK3R1 ZFPM1 FMNL1

1.36e-041886246686dbba990066568aa7573e70a7db8b4758f457
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SGIP1 PCSK6 SHANK3 DOC2B

1.36e-04188624aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACR INSM1 SKOR1

1.39e-04726237877184d5c9dd6d96476d71e7504e58c0b4d0f26
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG ANTXR1 LMOD1 FOXC1

1.39e-04189624975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM15 ACR PCSK6 SHANK3

1.39e-041896244bc3826e0515b3cf2e2ef72a7b2cf9c32ade1812
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACR FOXC1 DOC2B

1.39e-04189624fccadf8efbef17b7f12291b069c71060a71b04e2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 PIK3R1 ANTXR1 LMOD1

1.39e-04189624c734e5693808a0333139e87bd5be2597a9252afe
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 WIPF1 TGFBR3L FMNL1

1.42e-04190624ce049630ed69d31f00acbc1b5b0896efc592121f
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACR KIAA1217 TAMALIN SHANK3

1.42e-041906240a351609a72fd638c84b2435782e312ee6a33aac
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAM15 TAMALIN SHANK3 FOXC1

1.42e-04190624f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG ANTXR1 LMOD1 FOXC1

1.42e-0419062473d94fbae92029745989a8712eed8b99fd84c193
ToppCellIPF-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

SGIP1 PCSK6 SHANK3 DOC2B

1.42e-04190624ac029e73da5995221c9b9af551d85e4b835e21d6
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 WIPF1 PIK3R1 FMNL1

1.45e-04191624753deb090b7b78b4ef31604dbe5dbfc4dcf5184a
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 WIPF1 PIK3R1 FMNL1

1.45e-04191624355f5bcb220d917163833dead0050fc756c7b260
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 WIPF1 PIK3R1 FMNL1

1.45e-04191624337d7d7b89fe370e1fe005b9daad76c5dc3b8444
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 PIK3R1 ANTXR1 LMOD1

1.45e-04191624806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 FOXC1 DOC2B

1.45e-0419162454029b68fb78163c969890886ab0f8fb0dcf3c20
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

MAGEL2 SGIP1 ANTXR1 LMOD1

1.45e-04191624aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

ADAM15 KIAA1217 SHANK3 DOC2B

1.45e-04191624c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellIPF-Endothelial-Lymphatic|IPF / Disease state, Lineage and Cell class

SGIP1 PCSK6 SHANK3 DOC2B

1.48e-041926242496edd8f3a41146d418879de9ee2ccc7857431f
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

ADAM15 KIAA1217 SHANK3 DOC2B

1.48e-041926248a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellT/NK_cells-CD8+_Effector_T_cell|World / Lineage and Cell class

ACAP1 WIPF1 PIK3R1 DNAJB6

1.51e-0419362479fa0f482cd98642b1d38835cda98622f21e5bd0
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 TAMALIN FOXC1 DOC2B

1.51e-04193624c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

PIK3R1 DNAJB6 ZCCHC2 TAMALIN

1.51e-041936247256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 FOXC1 DOC2B

1.54e-04194624efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 WIPF1 PIK3R1 FMNL1

1.54e-04194624906fe1689906d1498acf6fd26a215c7e5a854a38
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 WIPF1 PIK3R1 FMNL1

1.54e-04194624af7428582b96a500f255c45efc02b6c10c4740d9
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 WIPF1 PIK3R1 FMNL1

1.54e-041946244138f3e8aa214504fca03962a43250670ae45215
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACR KIAA1217 TAMALIN SHANK3

1.54e-0419462468004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 SPEG ANTXR1 LMOD1

1.54e-04194624ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

ADAM15 KIAA1217 SHANK3 DOC2B

1.57e-04195624fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KIAA1217 MMP15 SHANK3 DOC2B

1.57e-0419562422a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAM15 TAMALIN SHANK3 DOC2B

1.57e-04195624517af3e6784f02c382df6f5691945eefaa9ec4ae
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPEG ANTXR1 LMOD1 FOXC1

1.57e-04195624c51b1bee79e77aa2ac444a4883ef533c0095eaad
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

ADAM15 KIAA1217 TAMALIN SHANK3

1.57e-0419562419e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPEG ANTXR1 LMOD1 FOXC1

1.57e-0419562443d372373367b71243c6ea958aedccde4478618f
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 SHANK3 FOXC1 DOC2B

1.57e-04195624752a100297c26732e12bbbf3ab27a2bd4f5ea06d
ToppCell3'_v3-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

PIK3R1 ZCCHC2 TAMALIN FMNL1

1.57e-041956241470f562ebcfe7da367964ecfd6c7f43bcdb4a73
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 PCSK6 SHANK3 DOC2B

1.60e-0419662409a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 PCSK6 SHANK3 DOC2B

1.60e-04196624e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCelldistal-Hematologic-Natural_Killer_T-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACAP1 WIPF1 PIK3R1 TGFBR3L

1.60e-0419662405d2a15ba702b07ef59c55891a06da02cdd15f7f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 SPEG ANTXR1 LMOD1

1.60e-04196624b8759e6231e0254797d6c30930407b79440c57bb
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 TAMALIN SHANK3 DOC2B

1.60e-0419662495c5b8fd4ebfae1f42de9b1475c1161d4a80e515
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid|BALF-PFMC / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACAP1 WIPF1 PIK3R1 FMNL1

1.60e-041966246361c37b0292ba9e5bf485a4809d2b0cd894c26e
ToppCellcellseq2|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRB3 PRB4 LMOD1 FOXC1

1.60e-04196624d9e1b8386817a668eca90288b6d0e20be4138bf8
ToppCellEndothelial|World / Lineage, Cell type, age group and donor

KIAA1217 TAMALIN SHANK3 DOC2B

1.60e-0419662496c6d78482a130ce4e29f6629972a06d10d7530e
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 SPEG HES7 LMOD1

1.63e-04197624cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCelldistal-Hematologic-Natural_Killer_T|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACAP1 WIPF1 PIK3R1 TGFBR3L

1.63e-041976245cb1b45f5dc8fbd9e54db9c943450ce2cc7000e4
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 SPEG ANTXR1 LMOD1

1.63e-04197624f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCelltumor_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lung / Location, Cell class and cell subclass

ACAP1 WIPF1 PIK3R1 DNAJB6

1.63e-04197624de26ca046038e34790cece24529a05d491e6f8ef
ToppCellmLN-(1)_T_cell-(17)_gd_T|mLN / shred on region, Cell_type, and subtype

SYNJ1 PIK3R1 VSTM2L TGFBR3L

1.63e-041976245c781ded147db2f3804ee1f21ef0898c4f354890
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAM15 KIAA1217 MMP15 SHANK3

1.63e-04197624b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAM15 TAMALIN SHANK3 DOC2B

1.63e-04197624b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRFN4 HCN1 LMOD1 DOC2B

1.63e-041976246806ec223e542f0475303698eb78c1cc527f5c6b
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

PIK3R1 ZCCHC2 TAMALIN FMNL1

1.63e-041976245c33454b10023decd2f5ccda9229b6512659711e
ToppCellmLN-T_cell-gd_T|mLN / Region, Cell class and subclass

SYNJ1 PIK3R1 VSTM2L TGFBR3L

1.63e-041976248ef03bdbd34a874671aebfdbb7111106aa37b2a9
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ACAP1 WIPF1 PIK3R1 NDST2

1.63e-0419762452246d1354c4e2b13d48c878643edf843d2b50d2
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

ADAM15 KIAA1217 TAMALIN SHANK3

1.63e-04197624f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WASL NDST2 ANTXR1 LMOD1

1.63e-04197624470e23dee4ca35e1fd021b7cdd58fcbc90639837
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIAA1217 ANTXR1 COBL MMP15

1.66e-041986245cfd1c030c0940136a397b5a4b5d6ecbaecf72eb
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIAA1217 ANTXR1 COBL MMP15

1.66e-04198624ff6d9455ebfe965cc6f48197172c0ebd3bddde81
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

PIK3R1 ZCCHC2 TAMALIN FMNL1

1.66e-0419862444417089b62056269cac38d3134ff209c05b7007
ToppCell10x3'2.3-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAM15 KIAA1217 MMP15 SHANK3

1.66e-041986242630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIAA1217 ANTXR1 COBL MMP15

1.66e-041986245375a2895cf995f0db4a61861093f01794707901
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 PCSK6 SHANK3 DOC2B

1.66e-041986249ab0db78394e730f6866b2db80047149024ad5f6
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 PCSK6 SHANK3 DOC2B

1.66e-04198624b3a020522e064bb61949d38e442f24026e339364
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIAA1217 ANTXR1 COBL MMP15

1.66e-0419862435edf6d5bedc2181fbdd56f43e458bc39f4eca16
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACAP1 PRB3 PRB4 PIK3R1

1.66e-04198624162881a04a981741a0e26e32e0c3c694282701c6
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 PCSK6 SHANK3 DOC2B

1.66e-04198624fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell10x3'2.3-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAM15 KIAA1217 MMP15 SHANK3

1.66e-041986241e83bec16dcd60460422625f89952ff506d6be51
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PIK3R1 ZCCHC2 TAMALIN FMNL1

1.66e-0419862428ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 PCSK6 SHANK3 DOC2B

1.66e-04198624e47d0e2c6353315c85d7007742bb16b0f05795ed
Diseaseserum albumin measurement

SCAF1 FAM117A MAP4K3 ADAM15 PIK3R1 ZFPM1 ZCCHC2

1.57e-04592587EFO_0004535
DiseaseLEOPARD Syndrome

PPP1R13L SOS2

8.55e-0422582C0175704
Diseasesuntan

SGIP1 KIAA1217 PRDM15

1.11e-03103583EFO_0004279
DiseaseQRS-T angle

SPEG ZFPM1 MMP15

1.20e-03106583EFO_0020097
Diseasesleep apnea measurement

WASL MLLT1 NANOS1

1.56e-03116583EFO_0007817

Protein segments in the cluster

PeptideGeneStartEntry
APPPNRAPPPSRPPP

ANTXR1

546

Q9H6X2
GPAKPPPPRKPLPAD

ADAM15

811

Q13444
PPRPPAAQPRPPPSP

ACR

336

P10323
GSPLPPASPRPPPRK

FAM117A

406

Q9C073
PRGQPPVPPKPSIRP

ACAP1

536

Q15027
GPAPRCAPPSPPPPV

CCSAP

71

Q6IQ19
PPPRRKGPLPAGPPP

FBXL19

191

Q6PCT2
FAVRPRKKGPPPPPP

CASKIN1

936

Q8WXD9
PRPPPPRLPPHKPVA

MAP4K3

476

Q8IVH8
PPPEHIPPPPRPPKR

PTPN1

301

P18031
PPPMRQGPPPIRPGP

MAGEL2

406

Q9UJ55
AAPRGPKGPPLPPPP

NAA80

231

Q93015
QPPPPGGKPERPPKP

MMP15

336

P51511
PLSKVPPPPARPPPR

NANOS1

266

Q8WY41
MPPRAPPAPGPRPPP

PCSK6

1

P29122
KKGGAPAAPPPPPPP

LMOD1

526

P29536
DPPPRRPAAPPGPPG

ZFPM1

711

Q8IX07
TPKPRPPRPLPVAPG

PIK3R1

86

P27986
PALPPPPPPARAFGP

TAMALIN

296

Q7Z6J2
PGIWPAPRGPPPPPR

CBLL1

451

Q75N03
APRGPPPPPRLQGPP

CBLL1

456

Q75N03
RPPPPPPAKAPDPGH

FCHSD1

671

Q86WN1
PAQPAGLRPPKPPRP

DNAJB6

251

O75190
PPNRGVPPAPPPPAA

HCN1

851

O60741
PSPGPSPARPPAKPP

DOC2B

96

Q14184
LKEPPPPGRQPPPAP

FOXC1

191

Q12948
PAPPPGPLPPPRPMR

COQ10A

31

Q96MF6
KKRRAPAPPPPQPPP

COBL

331

O75128
PAGPAAPPPKQPAPP

FMNL1

11

O95466
GPPPPPPPPPRASSK

MLLT1

271

Q03111
PRPKPVDPRPPAPRP

HES7

131

Q9BYE0
RAGPPAPAPPAPIPP

PPP1R13L

576

Q8WUF5
GPPPHPGKPERPPPQ

PRB4

91

P10163
PPPHPGKPERPPPQG

PRB4

176

P10163
RPPPPPGKPERPPPQ

PRB4

196

P10163
PAAALRPPGKRPPPP

INSM1

191

Q01101
RPPGKRPPPPTAAEP

INSM1

196

Q01101
PPPAPPRLEPRGPPA

NUTM2F

306

A1L443
PPPAPPRLEPRGPPA

NUTM2G

306

Q5VZR2
PPPPPVPPRRKKNRP

RUSC1

401

Q9BVN2
RPKTPPPAPAPAPGP

TAF3

791

Q5VWG9
APLPPPPPPPARKGS

SKOR1

576

P84550
PPRQPPPPKVKPRVP

SOS2

1176

Q07890
KRPPPPRPVAPPTRP

SYNJ1

1106

O43426
VPRPPPRPPKSVPGR

TGFBR3L

236

H3BV60
PPGSSPPRPAAPRPP

PRDM15

81

P57071
PPRPAAPRPPPPGGV

PRDM15

86

P57071
PAPKPPLPPPHRGPA

PRRC2A

406

P48634
GGKSPPPPPPPPRRS

KIAA1217

1041

Q5T5P2
EKPPPTGRPPAPPRA

INPPL1

936

O15357
RGPPPPKAHPRPPLP

INPPL1

1086

O15357
PKAHPRPPLPPGPSP

INPPL1

1091

O15357
CRPPPPPPPPAGPSR

ZCCHC2

41

Q9C0B9
PPKPGPPRRLSAPLP

RNF31

456

Q96EP0
KPQRPPPPGRPQGPP

PRB3

256

Q04118
APVPRPRGPPPPPGD

SF3B2

241

Q13435
PPPPPGPRKARAPPP

RNF225

161

M0QZC1
GPRKARAPPPPPPLR

RNF225

166

M0QZC1
PPSPRVGKRSPPGPP

SPEG

311

Q15772
APPAPPAPPPRGPKR

SHANK3

451

Q9BYB0
PPPRPPSRPKLPPGK

SGIP1

461

Q9BQI5
GRKPGDPPGPPRPPK

SCAF1

1281

Q9H7N4
AGPGPARPPVPPRPP

NDST2

61

P52849
DDKPPPPPPPVGNRP

WIPF1

261

O43516
PPPARGRGAPPPPPS

WASL

301

O00401
APPPPPPGRRANAPP

WIPF2

176

Q8TF74
REGPPAPPPVKPPPS

WIPF2

221

Q8TF74
RDPPSRGAAPPPPPP

WIPF2

316

Q8TF74
RGKPPPPPSRTPAGP

WIPF2

356

Q8TF74
PRLPPGRKPPGPPPG

WBP11

191

Q9Y2W2
APPAAPAPPPPKPGK

VSTM2L

176

Q96N03
APPAGPPPRPRPPAP

ZNF787

51

Q6DD87
PTPKAHPPRSPPPRP

LRFN4

566

Q6PJG9