Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

HSPD1 NLRP10 ABCF1 ABCA13 CHD9 OLA1 POLQ HSPA1A HSPA1B DNAH9 TOP2A TOP2B

1.34e-066147012GO:0140657
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase inhibitor activity

WASH6P WASH3P WASHC1

2.28e-068703GO:0141039
GeneOntologyMolecularFunctionATP hydrolysis activity

HSPD1 NLRP10 ABCF1 ABCA13 CHD9 OLA1 POLQ HSPA1A HSPA1B DNAH9

3.03e-064417010GO:0016887
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

HSPD1 KRAS RAB10 NLRP10 ABCF1 ABCA13 CHD9 OLA1 POLQ HSPA1A HSPA1B DNAH9

1.44e-057757012GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

HSPD1 KRAS RAB10 NLRP10 ABCF1 ABCA13 CHD9 OLA1 POLQ HSPA1A HSPA1B DNAH9

3.15e-058397012GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

HSPD1 KRAS RAB10 NLRP10 ABCF1 ABCA13 CHD9 OLA1 POLQ HSPA1A HSPA1B DNAH9

3.19e-058407012GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

HSPD1 KRAS RAB10 NLRP10 ABCF1 ABCA13 CHD9 OLA1 POLQ HSPA1A HSPA1B DNAH9

3.19e-058407012GO:0016818
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase regulator activity

WASH6P WASH3P WASHC1

3.24e-0518703GO:0035014
GeneOntologyMolecularFunctiondenatured protein binding

HSPA1A HSPA1B

3.63e-053702GO:0031249
GeneOntologyMolecularFunctionDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

TOP2A TOP2B

7.24e-054702GO:0003918
GeneOntologyMolecularFunctiondeath receptor agonist activity

HSPA1A HSPA1B

1.20e-045702GO:0038177
GeneOntologyMolecularFunctiontubulin binding

STIM1 WASH6P WASH3P TRAF3IP1 MAP1B WASHC1 AGTPBP1 CFAP157

1.23e-04428708GO:0015631
GeneOntologyMolecularFunctionATP-dependent protein disaggregase activity

HSPA1A HSPA1B

1.80e-046702GO:0140545
GeneOntologyMolecularFunctionC3HC4-type RING finger domain binding

HSPA1A HSPA1B

1.80e-046702GO:0055131
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

WASH6P WASH3P WASHC1

2.28e-0434703GO:0050750
GeneOntologyMolecularFunctiongamma-tubulin binding

WASH6P WASH3P WASHC1

3.19e-0438703GO:0043015
GeneOntologyMolecularFunctionDNA topoisomerase activity

TOP2A TOP2B

3.35e-048702GO:0003916
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

WASH6P WASH3P WASHC1

3.44e-0439703GO:0070325
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSPD1 HSPA1A HSPA1B

3.71e-0440703GO:0140662
GeneOntologyMolecularFunctionalpha-tubulin binding

WASH6P WASH3P WASHC1

8.06e-0452703GO:0043014
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

CHD9 POLQ TOP2A TOP2B

1.03e-03127704GO:0008094
GeneOntologyMolecularFunctionubiquitin protein ligase binding

HSPD1 WASH6P WASH3P WASHC1 HSPA1A HSPA1B

1.17e-03337706GO:0031625
GeneOntologyMolecularFunctioncadherin binding

RAB10 NOP56 CAPZB PKM OLA1 HSPA1A

1.21e-03339706GO:0045296
GeneOntologyMolecularFunctionprotein-containing complex destabilizing activity

HSPA1A HSPA1B

1.24e-0315702GO:0140776
GeneOntologyMolecularFunctionubiquitin-like protein ligase binding

HSPD1 WASH6P WASH3P WASHC1 HSPA1A HSPA1B

1.59e-03358706GO:0044389
GeneOntologyMolecularFunctionmisfolded protein binding

HSPA1A HSPA1B

1.79e-0318702GO:0051787
GeneOntologyMolecularFunctionprotein folding chaperone

HSPD1 HSPA1A HSPA1B

2.15e-0373703GO:0044183
GeneOntologyMolecularFunctiondeath receptor activity

HSPA1A HSPA1B

2.44e-0321702GO:0005035
GeneOntologyMolecularFunctiondouble-stranded RNA binding

HSPD1 HSPA1A HSPA1B

2.60e-0378703GO:0003725
GeneOntologyMolecularFunctionsyntaxin binding

TXLNA TXLNB SYT5

3.54e-0387703GO:0019905
GeneOntologyMolecularFunctionchromatin binding

SPI1 KDM3B POLQ KAT6B TSPYL4 TOP2A TOP2B MSL2

4.23e-03739708GO:0003682
GeneOntologyMolecularFunctioncytoskeletal protein binding

STIM1 WASH6P RAB10 WASH3P TRAF3IP1 MAP1B WASHC1 CAPZB AGTPBP1 CFAP157

4.80e-0310997010GO:0008092
GeneOntologyMolecularFunctioncell adhesion molecule binding

RAB10 NOP56 NRXN1 CAPZB PKM OLA1 HSPA1A

4.94e-03599707GO:0050839
GeneOntologyMolecularFunctionlipoprotein particle binding

HSPD1 STAB2

6.69e-0335702GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

HSPD1 STAB2

6.69e-0335702GO:0071814
GeneOntologyMolecularFunctionNF-kappaB binding

HSPA1A HSPA1B

7.07e-0336702GO:0051059
GeneOntologyMolecularFunctiontranscription regulator inhibitor activity

HSPA1A HSPA1B

7.07e-0336702GO:0140416
GeneOntologyBiologicalProcesspositive regulation of cholesterol import

WASH6P WASH3P WASHC1

5.93e-076653GO:1904109
GeneOntologyBiologicalProcessregulation of protein polymerization

WASH6P WASH3P MAP1B CARMIL1 WASHC1 CAPZB HSPA1A HSPA1B

6.39e-07231658GO:0032271
GeneOntologyBiologicalProcessregulation of cholesterol import

WASH6P WASH3P WASHC1

2.48e-069653GO:0060620
GeneOntologyBiologicalProcessregulation of Arp2/3 complex-mediated actin nucleation

WASH6P WASH3P CARMIL1 WASHC1

2.65e-0631654GO:0034315
GeneOntologyBiologicalProcessregulation of protein-containing complex assembly

WASH6P WASH3P TRAF3IP1 MAP1B PIEZO1 CARMIL1 WASHC1 CAPZB HSPA1A HSPA1B

2.85e-064896510GO:0043254
GeneOntologyBiologicalProcesspolar body extrusion after meiotic divisions

WASH6P WASH3P WASHC1

3.53e-0610653GO:0040038
GeneOntologyBiologicalProcesspositive regulation of sterol transport

WASH6P WASH3P ABCA13 WASHC1

7.54e-0640654GO:0032373
GeneOntologyBiologicalProcesspositive regulation of cholesterol transport

WASH6P WASH3P ABCA13 WASHC1

7.54e-0640654GO:0032376
GeneOntologyBiologicalProcessregulation of actin nucleation

WASH6P WASH3P CARMIL1 WASHC1

8.33e-0641654GO:0051125
GeneOntologyBiologicalProcessmeiotic cytokinesis

WASH6P WASH3P WASHC1

8.35e-0613653GO:0033206
GeneOntologyBiologicalProcesspositive regulation of single stranded viral RNA replication via double stranded DNA intermediate

TOP2A TOP2B

9.78e-062652GO:0045870
GeneOntologyBiologicalProcessprotein polymerization

WASH6P WASH3P MAP1B CARMIL1 WASHC1 CAPZB HSPA1A HSPA1B

9.83e-06334658GO:0051258
GeneOntologyBiologicalProcessArp2/3 complex-mediated actin nucleation

WASH6P WASH3P CARMIL1 WASHC1

1.45e-0547654GO:0034314
GeneOntologyBiologicalProcesscholesterol import

WASH6P WASH3P WASHC1

1.62e-0516653GO:0070508
GeneOntologyBiologicalProcessfemale meiotic nuclear division

WASH6P WASH3P WASHC1 TOP2A

2.17e-0552654GO:0007143
GeneOntologyBiologicalProcessdendritic cell antigen processing and presentation

WASH6P WASH3P WASHC1

3.81e-0521653GO:0002468
GeneOntologyBiologicalProcessregulation of erythrocyte differentiation

SPI1 INHBA HSPA1A HSPA1B

3.84e-0560654GO:0045646
GeneOntologyBiologicalProcessactin nucleation

WASH6P WASH3P CARMIL1 WASHC1

5.26e-0565654GO:0045010
GeneOntologyBiologicalProcessendosome to plasma membrane protein transport

WASH6P WASH3P WASHC1

5.77e-0524653GO:0099638
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

WASH6P WASH3P MAP1B CARMIL1 WASHC1 CAPZB HSPA1A HSPA1B

6.79e-05438658GO:1902903
GeneOntologyBiologicalProcessspindle organization

WASH6P WASH3P WASHC1 CEP126 HSPA1A HSPA1B

7.43e-05224656GO:0007051
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

WASH6P WASH3P TRAF3IP1 MAP1B CARMIL1 WASHC1 CAPZB HSPA1A HSPA1B

8.01e-05579659GO:0051493
GeneOntologyBiologicalProcessmeiotic spindle assembly

WASH6P WASH3P WASHC1

9.25e-0528653GO:0090306
GeneOntologyBiologicalProcessestablishment of protein localization to plasma membrane

WASH6P RAB10 WASH3P WASHC1

9.72e-0576654GO:0061951
GeneOntologyBiologicalProcesspositive regulation of protein localization to cell surface

WASH6P WASH3P WASHC1

1.03e-0429653GO:2000010
GeneOntologyBiologicalProcessprotein refolding

HSPD1 HSPA1A HSPA1B

1.14e-0430653GO:0042026
GeneOntologyBiologicalProcessspindle assembly

WASH6P WASH3P WASHC1 HSPA1A HSPA1B

1.21e-04153655GO:0051225
GeneOntologyBiologicalProcessnuclear chromosome segregation

WASH6P WASH3P WASHC1 HSPA1A HSPA1B TOP2A TOP2B

1.27e-04356657GO:0098813
GeneOntologyBiologicalProcessregulation of actin filament polymerization

WASH6P WASH3P CARMIL1 WASHC1 CAPZB

1.33e-04156655GO:0030833
GeneOntologyBiologicalProcessregulation of cholesterol transport

WASH6P WASH3P ABCA13 WASHC1

1.37e-0483654GO:0032374
GeneOntologyBiologicalProcessregulation of sterol transport

WASH6P WASH3P ABCA13 WASHC1

1.37e-0483654GO:0032371
GeneOntologyBiologicalProcesscellular heat acclimation

HSPA1A HSPA1B

1.45e-046652GO:0070370
GeneOntologyBiologicalProcessnegative regulation of filopodium assembly

NRXN1 CAPZB

1.45e-046652GO:0051490
GeneOntologyBiologicalProcessheat acclimation

HSPA1A HSPA1B

2.03e-047652GO:0010286
GeneOntologyBiologicalProcesspositive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

HSPA1A HSPA1B

2.03e-047652GO:0070434
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization

MAP1B HSPA1A HSPA1B

2.15e-0437653GO:0031116
GeneOntologyBiologicalProcessmeiotic spindle organization

WASH6P WASH3P WASHC1

2.15e-0437653GO:0000212
GeneOntologyBiologicalProcesspositive regulation of erythrocyte differentiation

INHBA HSPA1A HSPA1B

2.15e-0437653GO:0045648
GeneOntologyBiologicalProcessregulation of actin polymerization or depolymerization

WASH6P WASH3P CARMIL1 WASHC1 CAPZB

2.40e-04177655GO:0008064
GeneOntologyBiologicalProcessregulation of actin filament length

WASH6P WASH3P CARMIL1 WASHC1 CAPZB

2.59e-04180655GO:0030832
GeneOntologyBiologicalProcesspositive regulation of microtubule nucleation

HSPA1A HSPA1B

2.70e-048652GO:0090063
GeneOntologyBiologicalProcesspositive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

HSPA1A HSPA1B

2.70e-048652GO:0070426
GeneOntologyBiologicalProcesslow-density lipoprotein particle clearance

WASH6P WASH3P WASHC1

2.92e-0441653GO:0034383
GeneOntologyBiologicalProcesspositive regulation of protein polymerization

MAP1B CARMIL1 HSPA1A HSPA1B

3.03e-04102654GO:0032273
GeneOntologyBiologicalProcesspositive regulation of lipid transport

WASH6P WASH3P ABCA13 WASHC1

3.03e-04102654GO:0032370
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization or depolymerization

MAP1B HSPA1A HSPA1B

3.14e-0442653GO:0031112
GeneOntologyBiologicalProcessactin filament polymerization

WASH6P WASH3P CARMIL1 WASHC1 CAPZB

3.32e-04190655GO:0030041
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

WASH6P WASH3P TRAF3IP1 MAP1B WASHC1 CEP126 HSPA1A HSPA1B CFAP157

4.07e-04720659GO:0000226
GeneOntologyBiologicalProcess'de novo' protein folding

HSPD1 HSPA1A HSPA1B

4.12e-0446653GO:0006458
GeneOntologyBiologicalProcessexocytosis

WASH6P RAB10 WASH3P TXLNA SPI1 WASHC1 SYT5

4.23e-04434657GO:0006887
GeneOntologyBiologicalProcessmicrotubule-based process

WASH6P WASH3P TRAF3IP1 MAP1B WASHC1 CEP126 HSPA1A HSPA1B DNAH9 AGTPBP1 CFAP157

4.30e-0410586511GO:0007017
GeneOntologyBiologicalProcessDNA topological change

TOP2A TOP2B

4.33e-0410652GO:0006265
GeneOntologyBiologicalProcessoocyte maturation

WASH6P WASH3P WASHC1

4.39e-0447653GO:0001556
GeneOntologyBiologicalProcesssecretion by cell

STIM1 WASH6P RAB10 WASH3P TXLNA SPI1 NRXN1 INHBA WASHC1 SYT5 PLCD1

4.51e-0410646511GO:0032940
GeneOntologyBiologicalProcesscytokinesis

WASH6P WASH3P WASHC1 ATXN10 PRPF40A

4.60e-04204655GO:0000910
GeneOntologyBiologicalProcesspositive regulation of ubiquitin-dependent protein catabolic process

HSPA1A HSPA1B SH3RF3 AGTPBP1

4.62e-04114654GO:2000060
GeneOntologyBiologicalProcessregulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

HSPA1A HSPA1B

5.28e-0411652GO:0070432
GeneOntologyBiologicalProcessregulation of protein localization to cell surface

WASH6P WASH3P WASHC1

5.58e-0451653GO:2000008
GeneOntologyBiologicalProcessmeiotic chromosome segregation

WASH6P WASH3P WASHC1 TOP2A

5.97e-04122654GO:0045132
GeneOntologyBiologicalProcessnegative regulation of inclusion body assembly

HSPA1A HSPA1B

6.32e-0412652GO:0090084
GeneOntologyBiologicalProcesschromosome segregation

WASH6P WASH3P WASHC1 HSPA1A HSPA1B TOP2A TOP2B

6.38e-04465657GO:0007059
GeneOntologyBiologicalProcessregulation of extrinsic apoptotic signaling pathway in absence of ligand

INHBA HSPA1A HSPA1B

6.61e-0454653GO:2001239
GeneOntologyBiologicalProcessactin polymerization or depolymerization

WASH6P WASH3P CARMIL1 WASHC1 CAPZB

6.75e-04222655GO:0008154
GeneOntologyBiologicalProcessfemale gamete generation

WASH6P WASH3P INHBA WASHC1 TOP2A

6.89e-04223655GO:0007292
GeneOntologyBiologicalProcessregulation of protein ubiquitination

WASH6P WASH3P WASHC1 HSPA1A HSPA1B

7.31e-04226655GO:0031396
GeneOntologyBiologicalProcesspositive regulation of lipid localization

WASH6P WASH3P ABCA13 WASHC1

7.36e-04129654GO:1905954
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex assembly

MAP1B PIEZO1 CARMIL1 HSPA1A HSPA1B

7.46e-04227655GO:0031334
GeneOntologyBiologicalProcessmeiotic cell cycle

WASH6P WASH3P WASHC1 ZNF318 TOP2A TOP2B

8.14e-04350656GO:0051321
GeneOntologyBiologicalProcesscholesterol transport

WASH6P WASH3P ABCA13 WASHC1

8.48e-04134654GO:0030301
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor-mediated signaling pathway

HSPA1A HSPA1B

8.68e-0414652GO:1903265
GeneOntologyBiologicalProcessexport from cell

STIM1 WASH6P RAB10 WASH3P TXLNA SPI1 NRXN1 INHBA WASHC1 SYT5 PLCD1

8.80e-0411536511GO:0140352
GeneOntologyBiologicalProcessmeiotic nuclear division

WASH6P WASH3P WASHC1 TOP2A TOP2B

9.57e-04240655GO:0140013
GeneOntologyBiologicalProcesssterol transport

WASH6P WASH3P ABCA13 WASHC1

9.73e-04139654GO:0015918
GeneOntologyBiologicalProcessantigen processing and presentation

WASH6P RAB10 WASH3P WASHC1

9.73e-04139654GO:0019882
GeneOntologyBiologicalProcessplasma lipoprotein particle clearance

WASH6P WASH3P WASHC1

1.04e-0363653GO:0034381
GeneOntologyBiologicalProcessnuclear division

WASH6P WASH3P WASHC1 HSPA1A HSPA1B TOP2A TOP2B

1.12e-03512657GO:0000280
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

WASH6P WASH3P NRXN1 TRAF3IP1 MAP1B PIEZO1 CARMIL1 WASHC1 CAPZB HSPA1A HSPA1B

1.13e-0311896511GO:0044087
GeneOntologyBiologicalProcessregulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

HSPA1A HSPA1B

1.14e-0316652GO:0070424
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

NRXN1 TRAF3IP1 CARMIL1 WASHC1 CAPZB ATXN10 CEP126 CFAP157

1.17e-03670658GO:0120031
GeneOntologyBiologicalProcesspositive regulation of proteolysis involved in protein catabolic process

HSPA1A HSPA1B SH3RF3 AGTPBP1

1.23e-03148654GO:1903052
GeneOntologyBiologicalProcesspositive regulation of interleukin-8 production

NLRP10 HSPA1A HSPA1B

1.24e-0367653GO:0032757
GeneOntologyBiologicalProcessmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

NIFK RBM34

1.29e-0317652GO:0000463
GeneOntologyBiologicalProcessregulation of microtubule polymerization

MAP1B HSPA1A HSPA1B

1.35e-0369653GO:0031113
GeneOntologyBiologicalProcesscell projection assembly

NRXN1 TRAF3IP1 CARMIL1 WASHC1 CAPZB ATXN10 CEP126 CFAP157

1.35e-03685658GO:0030031
GeneOntologyBiologicalProcesssecretion

STIM1 WASH6P RAB10 WASH3P TXLNA SPI1 NRXN1 INHBA WASHC1 SYT5 PLCD1

1.40e-0312216511GO:0046903
GeneOntologyBiologicalProcessresolution of meiotic recombination intermediates

TOP2A TOP2B

1.45e-0318652GO:0000712
GeneOntologyBiologicalProcessnegative regulation of cellular component organization

NRXN1 TRAF3IP1 MAP1B FAT3 CARMIL1 CAPZB HSPA1A HSPA1B TOP2A

1.48e-03864659GO:0051129
GeneOntologyBiologicalProcesscell division

WASH6P RAB10 WASH3P WASHC1 ATXN10 CDK14 PRPF40A TOP2A

1.51e-03697658GO:0051301
GeneOntologyBiologicalProcessmeiotic cell cycle process

WASH6P WASH3P WASHC1 TOP2A TOP2B

1.56e-03268655GO:1903046
GeneOntologyBiologicalProcessregulation of single stranded viral RNA replication via double stranded DNA intermediate

TOP2A TOP2B

1.62e-0319652GO:0045091
GeneOntologyBiologicalProcessregulation of microtubule nucleation

HSPA1A HSPA1B

1.62e-0319652GO:0010968
GeneOntologyBiologicalProcesscell cycle process

WASH6P WASH3P INHBA WASHC1 ATXN10 CEP126 CDK14 HSPA1A HSPA1B PRPF40A TOP2A TOP2B

1.63e-0314416512GO:0022402
GeneOntologyBiologicalProcessregulation of protein modification by small protein conjugation or removal

WASH6P WASH3P WASHC1 HSPA1A HSPA1B

1.64e-03271655GO:1903320
GeneOntologyBiologicalProcesssingle stranded viral RNA replication via double stranded DNA intermediate

TOP2A TOP2B

1.79e-0320652GO:0039692
GeneOntologyBiologicalProcessnucleotide-binding oligomerization domain containing 2 signaling pathway

HSPA1A HSPA1B

1.79e-0320652GO:0070431
GeneOntologyBiologicalProcessregulation of post-translational protein modification

WASH6P WASH3P WASHC1 HSPA1A HSPA1B

1.80e-03277655GO:1901873
GeneOntologyBiologicalProcesspost-translational protein modification

WASH6P WASH3P RBBP6 WASHC1 USP24 HSPA1A HSPA1B SH3RF3 AGTPBP1 MSL2

1.85e-0310746510GO:0043687
GeneOntologyBiologicalProcessregulation of inclusion body assembly

HSPA1A HSPA1B

1.98e-0321652GO:0090083
GeneOntologyBiologicalProcessprotein localization to cell surface

WASH6P WASH3P WASHC1

1.99e-0379653GO:0034394
GeneOntologyBiologicalProcessorganelle fission

WASH6P WASH3P WASHC1 HSPA1A HSPA1B TOP2A TOP2B

2.09e-03571657GO:0048285
GeneOntologyCellularComponentWASH complex

WASH6P WASH3P WASHC1 CAPZB

2.02e-0715754GO:0071203
GeneOntologyCellularComponentexocyst

WASH6P RAB10 WASH3P WASHC1

8.73e-0721754GO:0000145
GeneOntologyCellularComponentmicrotubule organizing center

WASH6P WASH3P UBN1 TRAF3IP1 RBBP6 WASHC1 ATXN10 CEP126 OLA1 HSPA1A HSPA1B TOP2A CFAP157

2.12e-059197513GO:0005815
GeneOntologyCellularComponentBLOC-1 complex

WASH6P WASH3P WASHC1

3.48e-0518753GO:0031083
GeneOntologyCellularComponentcentriole

WASH3P WASHC1 ATXN10 HSPA1A HSPA1B TOP2A

3.58e-05172756GO:0005814
GeneOntologyCellularComponentrecycling endosome membrane

WASH6P RAB10 WASH3P WASHC1 SYT5

5.17e-05112755GO:0055038
GeneOntologyCellularComponentBLOC complex

WASH6P WASH3P WASHC1

7.46e-0523753GO:0031082
GeneOntologyCellularComponentvesicle tethering complex

WASH6P RAB10 WASH3P WASHC1

1.31e-0472754GO:0099023
GeneOntologyCellularComponentlamellipodium

WASH6P WASH3P PIEZO1 CARMIL1 WASHC1 CAPZB

1.78e-04230756GO:0030027
GeneOntologyCellularComponentCOP9 signalosome

THEMIS HSPA1A HSPA1B

3.42e-0438753GO:0008180
GeneOntologyCellularComponentcentrosome

WASH6P WASH3P UBN1 TRAF3IP1 RBBP6 WASHC1 CEP126 OLA1 HSPA1A HSPA1B

4.13e-047707510GO:0005813
GeneOntologyCellularComponentrecycling endosome

WASH6P RAB10 WASH3P WASHC1 SYT5

1.22e-03222755GO:0055037
GeneOntologyCellularComponentcilium

HSPD1 RAB10 TRAF3IP1 MAP1B LYZL4 PKM ATXN10 CEP126 DNAH9 CFAP157

1.34e-038987510GO:0005929
GeneOntologyCellularComponentcell cortex

STIM1 WASH6P RAB10 WASH3P WASHC1 CAPZB

2.16e-03371756GO:0005938
MousePhenoabnormal ectoplacental cavity morphology

WASH6P RAB10 WASH3P WASHC1

3.77e-0715594MP:0011202
MousePhenoabnormal extraembryonic coelom morphology

WASH6P RAB10 WASH3P WASHC1

1.32e-0620594MP:0011200
MousePhenoabnormal amniotic cavity morphology

WASH6P RAB10 WASH3P WASHC1

3.39e-0625594MP:0011199
MousePhenoabsent subplate

MAP1B TOP2B

1.05e-044592MP:0008443
DomainDNA_topoisoIV

TOP2A TOP2B

1.38e-052702PF00521
DomainTopo_IIA_A/C_ab

TOP2A TOP2B

1.38e-052702IPR013758
DomainTopo_IIA_A_a

TOP2A TOP2B

1.38e-052702IPR013757
DomainTopo_IIA_cen_dom

TOP2A TOP2B

1.38e-052702IPR013759
Domain-

TOP2A TOP2B

1.38e-0527023.40.50.670
DomainDTHCT

TOP2A TOP2B

1.38e-052702IPR012542
DomainTOP4c

TOP2A TOP2B

1.38e-052702SM00434
DomainTOP2c

TOP2A TOP2B

1.38e-052702SM00433
DomainTopo_IIA-like_dom

TOP2A TOP2B

1.38e-052702IPR013760
DomainTopo_IIA_bsu_dom2

TOP2A TOP2B

1.38e-052702IPR013506
DomainDTHCT

TOP2A TOP2B

1.38e-052702PF08070
DomainDNA_gyraseB

TOP2A TOP2B

1.38e-052702PF00204
Domain-

TOP2A TOP2B

1.38e-0527021.10.268.10
DomainTOPRIM_C

TOP2A TOP2B

1.38e-052702IPR031660
DomainTOPRIM_C

TOP2A TOP2B

1.38e-052702PF16898
Domain-

TOP2A TOP2B

1.38e-0527023.90.199.10
DomainTopoIIA_CS

TOP2A TOP2B

1.38e-052702IPR018522
DomainTopo_IIA_A/C

TOP2A TOP2B

1.38e-052702IPR002205
DomainTopo_IIA

TOP2A TOP2B

1.38e-052702IPR001241
DomainTOPOISOMERASE_II

TOP2A TOP2B

1.38e-052702PS00177
Domain-

TOP2A TOP2B

4.14e-0537023.30.1360.40
DomainArg_repress_C-like

TOP2A TOP2B

4.14e-053702IPR024946
DomainTaxilin_fam

TXLNA TXLNB

4.14e-053702IPR026183
DomainFumarylacetoacetase_C-rel

FAHD2B FAHD2A

8.27e-054702IPR011234
DomainFAA_hydrolase

FAHD2B FAHD2A

8.27e-054702PF01557
DomainToprim_domain

TOP2A TOP2B

8.27e-054702IPR006171
Domain-

FAHD2B FAHD2A

8.27e-0547023.90.850.10
DomainToprim

TOP2A TOP2B

8.27e-054702PF01751
DomainTOPRIM

TOP2A TOP2B

8.27e-054702PS50880
DomainTaxilin

TXLNA TXLNB

8.27e-054702PF09728
DomainNBPF_dom

NBPF9 NBPF14

7.45e-0411702IPR010630
DomainNBPF

NBPF9 NBPF14

7.45e-0411702PS51316
DomainDUF1220

NBPF9 NBPF14

7.45e-0411702PF06758
DomainHSP70

HSPA1A HSPA1B

1.61e-0316702PF00012
Domain-

KRAS RAB10 NLRP10 ABCF1 ABCA13 CHD9 OLA1 POLQ DNAH9

1.81e-037467093.40.50.300
DomainHSP70_2

HSPA1A HSPA1B

1.82e-0317702PS00329
DomainHSP70_3

HSPA1A HSPA1B

1.82e-0317702PS01036
DomainHSP70_1

HSPA1A HSPA1B

1.82e-0317702PS00297
DomainHATPase_c

TOP2A TOP2B

2.04e-0318702SM00387
DomainHsp_70_fam

HSPA1A HSPA1B

2.04e-0318702IPR013126
DomainHATPase_c

TOP2A TOP2B

2.27e-0319702PF02518
Domain-

TOP2A TOP2B

2.52e-03207023.30.565.10
Domain-

TOP2A TOP2B

2.78e-03217023.30.230.10
DomainHATPase_C

TOP2A TOP2B

2.78e-0321702IPR003594
DomainRibosomal_S5_D2-typ_fold_subgr

TOP2A TOP2B

3.05e-0322702IPR014721
DomainWH2

WASHC1 WASH2P

3.62e-0324702PS51082
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF19 NBPF12 NBPF9 NBPF10 NBPF14 NBPF20

5.52e-122178616079250
Pubmed

Characterization of the murine orthologue of a novel human subtelomeric multigene family.

WASH6P WASH3P WASHC1 WASH2P

1.17e-10578411701968
Pubmed

Human subtelomeric WASH genes encode a new subclass of the WASP family.

WASH6P WASH3P WASHC1 WASH2P

3.50e-10678418159949
Pubmed

Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.

WASH6P WASH3P WASHC1 WASH2P

1.63e-09878410655549
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

HSPD1 STIM1 RAB10 ARFGAP2 NOP56 MAP1B CARMIL1 ETFB USP24 CAPZB PKM HSPA1B PRPF40A

6.05e-09708781339231216
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

HSPD1 RAB10 NIFK ABCF1 NOP56 MAP1B ETFB CAPZB PKM ZNF318 ATXN10 OLA1 PRPF40A TOP2A TOP2B

7.57e-091024781524711643
Pubmed

WASH Regulates Glucose Homeostasis by Facilitating Glut2 Receptor Recycling in Pancreatic β-Cells.

WASH6P WASH3P WASHC1

1.09e-08378330425062
Pubmed

Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.

WASH6P WASH3P WASHC1

1.09e-08378338086439
Pubmed

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.

WASH6P WASH3P WASHC1

1.09e-08378325225459
Pubmed

The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

WASH6P WASH3P WASHC1 CAPZB

1.14e-081278419922875
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NOP56 MAP1B RBBP6 USP24 CAPZB PKM KDM3B ZNF318 PRPF40A TOP2A DHRS7B

4.11e-08549781138280479
Pubmed

Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation.

WASH6P WASH3P WASHC1

4.33e-08478332492429
Pubmed

The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.

WASH6P WASH3P WASHC1

4.33e-08478331167970
Pubmed

WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function.

WASH6P WASH3P WASHC1

4.33e-08478323275443
Pubmed

Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production.

WASH6P WASH3P WASHC1

4.33e-08478332879135
Pubmed

Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks.

WASH6P WASH3P WASHC1

4.33e-08478322718907
Pubmed

Dendritic cells utilize the evolutionarily conserved WASH and retromer complexes to promote MHCII recycling and helper T cell priming.

WASH6P WASH3P WASHC1

4.33e-08478324886983
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

HSPD1 RAB10 NIFK NOP56 MAP1B CAPZB PKM HSPA1A HSPA1B PRPF40A TOP2A TOP2B

6.44e-08714781228302793
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

RAB10 NIFK SPI1 NOP56 ETFB PRPF40A TOP2A TOP2B RBM34

7.40e-0834078929478914
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

HSPD1 NIFK TXLNA TRMT6 ABCF1 NOP56 ETFB CAPZB PKM ATXN10 OLA1 HSPA1A PRPF40A TOP2A TOP2B RBM34

9.06e-081425781630948266
Pubmed

Functional characterization of Wiskott-Aldrich syndrome protein and scar homolog (WASH), a bi-modular nucleation-promoting factor able to interact with biogenesis of lysosome-related organelle subunit 2 (BLOS2) and gamma-tubulin.

WASH6P WASH3P WASHC1

1.08e-07578320308062
Pubmed

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.

WASH6P WASH3P WASHC1

1.08e-07578324344185
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

HSPD1 RAB10 NIFK ABCF1 NOP56 HSPA1A HSPA1B PRPF40A TOP2A TOP2B RBM34

1.09e-07605781128977666
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

HSPD1 RAB10 NIFK ABCF1 NOP56 FAM32A NRXN1 MAP1B RBBP6 CAPZB PKM CHD9 PRPF40A TOP2B

1.17e-071082781438697112
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

HSPD1 NIFK TRMT6 ABCF1 NOP56 PKM HSPA1A PRPF40A RBM34 DHRS7B

1.39e-07486781030940648
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

HSPD1 RAB10 STAB2 MAP1B SETBP1 ETFB CAPZB PKM SYT5 ATXN10 HSPA1B

1.42e-07621781122794259
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

RAB10 NIFK TXLNA ABCF1 FAM32A CAPZB PKM KDM3B CHD9 ZNF318 OLA1 HSPA1B TOP2A TOP2B

1.48e-071103781434189442
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

HSPD1 ABCF1 NOP56 MAP1B RBBP6 CARMIL1 PKM KDM3B ZNF318 HSPA1A PRPF40A TOP2A TOP2B

1.53e-07934781333916271
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ABCF1 UBN1 RBBP6 CARMIL1 USP24 KDM3B ZNF318 KAT6B PRPF40A TOP2A TOP2B AGTPBP1

1.54e-07774781215302935
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

HSPD1 STIM1 NIFK TXLNA ABCF1 NOP56 CASKIN2 PIEZO1 ETFB ATXN10 HSPA1A HSPA1B PRPF40A TOP2B RBM34 AGTPBP1

1.61e-071487781633957083
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

HSPD1 RAB10 NIFK ABCF1 NOP56 RBBP6 ETFB USP24 PKM KDM3B HSPA1A PRPF40A TOP2A TOP2B RBM34

2.05e-071318781530463901
Pubmed

WASH complex regulates Arp2/3 complex for actin-based polar body extrusion in mouse oocytes.

WASH6P WASH3P WASHC1

2.16e-07678324998208
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

NBPF12 NOP56 MAP1B ABCA13 NBPF9 SETBP1 NBPF10 PKM NBPF14 AGTPBP1

2.29e-07513781025798074
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

HSPD1 RAB10 NOP56 RBBP6 ABCA13 CAPZB PKM HSPA1A PRPF40A TOP2A TOP2B

2.31e-07652781131180492
Pubmed

WASH maintains NKp46+ ILC3 cells by promoting AHR expression.

WASH6P WASH3P WASHC1

3.77e-07778328589939
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

STIM1 NIFK TXLNA TRMT6 UBN1 MAP1B CASKIN2 WASHC1 CAPZB ZNF318 RBM34

3.98e-07689781136543142
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

STIM1 RAB10 ARFGAP2 NOP56 CASKIN2 CARMIL1 CAPZB PKM OLA1 HSPA1A

5.53e-07565781025468996
Pubmed

STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.

HSPD1 TRMT6 ABCF1 NOP56 MAP1B PKM HSPA1B RBM34

5.74e-0731678831665637
Pubmed

The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse.

WASH6P WASH3P WASHC1

6.03e-07878327927957
Pubmed

A FAM21-containing WASH complex regulates retromer-dependent sorting.

WASH6P WASH3P WASHC1

6.03e-07878319922874
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

UBN1 MAP1B PKM KDM3B ZNF318 HSPA1A PRPF40A TOP2A TOP2B

6.96e-0744478934795231
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

HSPD1 RAB10 FAHD2B ETFB CAPZB FAHD2A HSPA1A HSPA1B

8.13e-0733178829199018
Pubmed

RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy.

WASH6P WASH3P WASHC1

9.03e-07978324980959
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

HSPD1 RAB10 NOP56 MAP1B USP24 PKM HSPA1A HSPA1B

1.08e-0634478830333137
Pubmed

Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.

HSPD1 RAB10 ETFB PKM HSPA1A HSPA1B PRPF40A

1.22e-0624178723125841
Pubmed

Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination.

WASH6P WASH3P WASHC1

1.29e-061078323452853
Pubmed

Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.

HSPD1 HSPA1A HSPA1B

1.29e-061078311932435
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF12 NBPF9 NBPF14

1.29e-061078322973535
Pubmed

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination.

WASH6P WASH3P WASHC1

1.29e-061078323974797
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

HSPD1 RAB10 NIFK ABCF1 NOP56 RBBP6 CAPZB PKM HSPA1A HSPA1B PRPF40A TOP2A

1.32e-06949781236574265
Pubmed

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.

WASH6P WASH3P WASHC1

1.77e-061178326965651
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

HSPD1 TXLNA ABCF1 NOP56 MAP1B CAPZB PKM CHD9 ATXN10 OLA1 PRPF40A

1.90e-06809781132129710
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

HSPD1 NIFK ABCF1 NOP56 RBBP6 CAPZB PKM HSPA1A PRPF40A RBM34

2.09e-06655781035819319
Pubmed

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.

WASH6P WASH3P WASHC1

2.35e-061278327390154
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

HSPD1 STIM1 NIFK TXLNA ABCF1 NOP56 CARMIL1 USP24 CAPZB PKM OLA1 HSPA1A TOP2A TOP2B

2.85e-061415781428515276
Pubmed

Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption.

HSPD1 HSPA1A HSPA1B

3.05e-061378317661394
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

TXLNA MAP1B RBBP6 KDM3B ZNF318 HSPA1A HSPA1B PRPF40A

3.26e-0639978835987950
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

HSPD1 KRAS RAB10 ABCF1 RBBP6 WDR87 CAPZB PKM CHD9 OLA1 HSPA1A PRPF40A TOP2A

3.85e-061247781327684187
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

HSPD1 NIFK TXLNA TRMT6 ABCF1 NOP56 RBBP6 CAPZB PKM HSPA1B TOP2A RBM34 DHRS7B

4.20e-061257781336526897
Pubmed

Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting.

WASH6P WASH3P WASHC1

4.84e-061578329893854
Pubmed

DNA topoisomerase II is dispensable for oocyte meiotic resumption but is essential for meiotic chromosome condensation and separation in mice.

TOP2A TOP2B

4.97e-06278224048577
Pubmed

Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.

HSPA1A HSPA1B

4.97e-06278212411538
Pubmed

Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.

HSPA1A HSPA1B

4.97e-0627822868009
Pubmed

Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.

HSPA1A HSPA1B

4.97e-06278224328534
Pubmed

In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.

HSPA1A HSPA1B

4.97e-0627823786141
Pubmed

Quantitative proteome analysis of multidrug resistance in human ovarian cancer cell line.

HSPD1 PKM

4.97e-06278220082317
Pubmed

Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.

TOP2A TOP2B

4.97e-06278219222228
Pubmed

Evidence for a mutant allele of the gene for DNA topoisomerase II in adriamycin-resistant P388 murine leukemia cells.

TOP2A TOP2B

4.97e-0627822555055
Pubmed

Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.

HSPA1A HSPA1B

4.97e-06278226923070
Pubmed

Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.

TOP2A TOP2B

4.97e-0627821331984
Pubmed

Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.

TOP2A TOP2B

4.97e-06278231106979
Pubmed

A biochemical analysis of topoisomerase II alpha and beta kinase activity found in HIV-1 infected cells and virus.

TOP2A TOP2B

4.97e-06278216091284
Pubmed

Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.

HSPA1A HSPA1B

4.97e-06278216482515
Pubmed

Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.

HSPA1A HSPA1B

4.97e-06278211864979
Pubmed

[Role of heat shock proteins in the cardioprotection of regular moderate alcohol consumption].

HSPD1 HSPA1A

4.97e-06278226902796
Pubmed

Hippocampal 72-kDa heat shock protein expression varies according to mice learning performance independently from chronic exposure to stress.

HSPA1A HSPA1B

4.97e-06278215719414
Pubmed

Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.

HSPA1A HSPA1B

4.97e-06278226976620
Pubmed

Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.

HSPA1A HSPA1B

4.97e-06278221187371
Pubmed

Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer.

HSPA1A HSPA1B

4.97e-06278220430459
Pubmed

Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.

HSPA1A HSPA1B

4.97e-06278220235222
Pubmed

Genetic determinants of HSP70 gene expression following heat shock.

HSPA1A HSPA1B

4.97e-06278220876613
Pubmed

The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.

HSPA1A HSPA1B

4.97e-06278220223214
Pubmed

Mining topoisomerase isoforms in gastric cancer.

TOP2A TOP2B

4.97e-06278232535049
Pubmed

Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development.

TOP2A TOP2B

4.97e-0627821380833
Pubmed

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.

HSPA1A HSPA1B

4.97e-06278220093776
Pubmed

Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.

HSPA1A HSPA1B

4.97e-06278223704948
Pubmed

Structure and expression of the human gene encoding major heat shock protein HSP70.

HSPA1A HSPA1B

4.97e-0627822858050
Pubmed

Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release.

HSPA1A HSPA1B

4.97e-06278217513788
Pubmed

IL-6 activates HSP72 gene expression in human skeletal muscle.

HSPA1A HSPA1B

4.97e-06278212207910
Pubmed

Inducing heat shock protein 70 expression provides a robust antithrombotic effect with minimal bleeding risk.

HSPA1A HSPA1B

4.97e-06278228837204
Pubmed

WASH and the Arp2/3 complex regulate endosome shape and trafficking.

WASH3P WASHC1

4.97e-06278220175130
Pubmed

Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals.

HSPA1A HSPA1B

4.97e-06278229572464
Pubmed

Protective effect of heat shock proteins 70.1 and 70.3 on retinal photic injury after systemic hyperthermia.

HSPA1A HSPA1B

4.97e-06278215988927
Pubmed

Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.

HSPA1A HSPA1B

4.97e-06278226448330
Pubmed

Oncogenic KRAS suppresses store-operated Ca2+ entry and ICRAC through ERK pathway-dependent remodelling of STIM expression in colorectal cancer cell lines.

STIM1 KRAS

4.97e-06278229748135
Pubmed

HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts.

HSPA1A HSPA1B

4.97e-06278212714332
Pubmed

Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis.

HSPA1A HSPA1B

4.97e-06278219299581
Pubmed

Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene.

HSPA1A HSPA1B

4.97e-06278211713291
Pubmed

Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice.

HSPA1A HSPA1B

4.97e-06278221108992
Pubmed

Involvement of human topoisomerase II isoforms in HIV-1 reverse transcription.

TOP2A TOP2B

4.97e-06278223399433
InteractionKCNA3 interactions

HSPD1 STIM1 RAB10 ARFGAP2 NOP56 MAP1B RBBP6 ABCA13 CARMIL1 ETFB USP24 CAPZB PKM CHD9 POLQ HSPA1B PRPF40A

2.34e-088717717int:KCNA3
InteractionWASHC1 interactions

KRAS WASH6P WASH3P TXLNA WASHC1 CAPZB HSPA1A

7.06e-0894777int:WASHC1
InteractionDCPS interactions

KRAS RAB10 NIFK SPI1 NOP56 ETFB HSPA1A PRPF40A TOP2A TOP2B RBM34

2.92e-073947711int:DCPS
InteractionKIF23 interactions

HSPD1 KRAS RAB10 NIFK TXLNA ABCF1 NOP56 ABCA13 ETFB CAPZB CHD9 HSPA1A PRPF40A TOP2A TOP2B RBM34

1.41e-0610317716int:KIF23
InteractionIFI16 interactions

HSPD1 NIFK TRMT6 ABCF1 NOP56 MAP1B PKM ATXN10 HSPA1B PRPF40A TOP2A TOP2B RBM34

2.82e-067147713int:IFI16
InteractionNUP43 interactions

HSPD1 STIM1 NIFK NOP56 FAM32A RBBP6 CHD9 ZNF318 DNAH9 TOP2A TOP2B MSL2

4.15e-066257712int:NUP43
InteractionRPS24 interactions

KRAS NIFK NOP56 FAM32A ETFB CAPZB OLA1 HSPA1A TOP2A TOP2B RBM34

5.13e-065297711int:RPS24
InteractionCDH1 interactions

HSPD1 STIM1 KRAS RAB10 ARFGAP2 NOP56 CASKIN2 CARMIL1 CAPZB PKM OLA1 HSPA1A TOP2A

6.24e-067687713int:CDH1
InteractionFAHD2B interactions

HSPD1 FAHD2B FAHD2A

1.15e-0512773int:FAHD2B
InteractionWASHC3 interactions

WASH6P WASH3P TXLNA TXLNB WASHC1 CAPZB

1.24e-05134776int:WASHC3
InteractionHTT interactions

HSPD1 RAB10 STAB2 MAP1B SETBP1 ETFB USP24 CAPZB PKM SYT5 ATXN10 CEP126 HSPA1A PRPF40A

1.26e-059497714int:HTT
InteractionCEBPA interactions

RAB10 NIFK TXLNA ABCF1 SPI1 NOP56 FAM32A CAPZB PKM KDM3B CHD9 ZNF318 OLA1 HSPA1B TOP2A TOP2B

1.56e-0512457716int:CEBPA
InteractionBRD3 interactions

NIFK ABCF1 NOP56 RBBP6 FIBP CHD9 PRPF40A TOP2A TOP2B AGTPBP1

1.80e-054947710int:BRD3
InteractionBRD7 interactions

HSPD1 NIFK TRMT6 ABCF1 NOP56 USP24 PKM HSPA1A PRPF40A RBM34 DHRS7B

2.90e-056377711int:BRD7
InteractionFBL interactions

HSPD1 KRAS NIFK NOP56 FAM32A ZNF318 OLA1 HSPA1A TOP2A TOP2B RBM34

2.99e-056397711int:FBL
InteractionOBSL1 interactions

HSPD1 KRAS NIFK ABCF1 NOP56 CAPZB PKM POLQ PRPF40A TOP2A TOP2B RBM34 AGTPBP1

3.42e-059027713int:OBSL1
InteractionWASH6P interactions

WASH6P WASHC1 CAPZB

3.51e-0517773int:WASH6P
InteractionCAPZB interactions

HSPD1 KRAS WASH6P WASH3P TRMT6 RBBP6 CARMIL1 WASHC1 CAPZB HSPA1A HSPA1B TOP2A TOP2B AGTPBP1

3.82e-0510497714int:CAPZB
InteractionKIF20A interactions

HSPD1 RAB10 NIFK ABCF1 NOP56 RBBP6 CAPZB PKM ZNF318 PLCD1 CDK14 PRPF40A TOP2A TOP2B

3.94e-0510527714int:KIF20A
InteractionNBPF9 interactions

KRAS NBPF9

4.31e-053772int:NBPF9
InteractionMAD2L1 interactions

KRAS ARFGAP2 CAPZB KDM3B CHD9 ZNF318 HSPA1A

5.02e-05252777int:MAD2L1
InteractionFBXL4 interactions

HSPD1 PKM PLCD1 HSPA1A HSPA1B

5.35e-05106775int:FBXL4
InteractionGAPDH interactions

HSPD1 KRAS ABCF1 MAP1B CAPZB PKM KDM3B OLA1 HSPA1A PRPF40A TOP2B

5.68e-056867711int:GAPDH
InteractionSLX4 interactions

HSPD1 UBN1 FAM32A CAPZB PKM KDM3B CHD9 ZNF318 POLQ HSPA1A

6.23e-055727710int:SLX4
InteractionDDRGK1 interactions

HSPD1 STIM1 KRAS RAB10 NIFK ABCF1 NOP56 CAPZB PKM ATXN10 HSPA1A PRPF40A TOP2A RBM34 DHRS7B

6.53e-0512497715int:DDRGK1
InteractionSMARCA4 interactions

KRAS UBN1 NOP56 USP24 ATXN10 HSPA1A PRPF40A TOP2A TOP2B

6.56e-05462779int:SMARCA4
InteractionNR2C2 interactions

HSPD1 RAB10 NIFK ABCF1 UBN1 NOP56 RBBP6 ETFB USP24 PKM KDM3B HSPA1A PRPF40A TOP2A TOP2B RBM34

6.63e-0514037716int:NR2C2
InteractionHSD3B2 interactions

KRAS TOP2A TOP2B

6.79e-0521773int:HSD3B2
InteractionNEK4 interactions

NBPF12 NOP56 MAP1B ABCA13 NBPF9 SETBP1 NBPF10 PKM NBPF14 AGTPBP1

7.20e-055827710int:NEK4
InteractionEIF6 interactions

KRAS ABCF1 FIBP CEP126 HSPA1A TOP2A TOP2B RBM34

7.60e-05365778int:EIF6
InteractionNAA40 interactions

HSPD1 ABCF1 NOP56 MAP1B RBBP6 CARMIL1 PKM KDM3B ZNF318 HSPA1A PRPF40A TOP2A TOP2B

7.82e-059787713int:NAA40
InteractionPHB1 interactions

HSPD1 KRAS RAB10 ABCF1 NRXN1 TRAF3IP1 MAP1B CAPZB PKM OLA1 HSPA1A HSPA1B RBM34 DHRS7B

7.99e-0511237714int:PHB1
InteractionCUL7 interactions

HSPD1 RAB10 NIFK NOP56 MAP1B ETFB CAPZB PKM OLA1 PRPF40A TOP2A TOP2B

8.16e-058457712int:CUL7
InteractionDDX23 interactions

KRAS NIFK NOP56 MAP1B RBBP6 PRPF40A TOP2A TOP2B RBM34

8.79e-05480779int:DDX23
InteractionMECP2 interactions

HSPD1 RAB10 NIFK ABCF1 SPI1 NOP56 FAM32A NRXN1 MAP1B RBBP6 CAPZB PKM CHD9 PRPF40A TOP2B

9.15e-0512877715int:MECP2
InteractionDNAJB6 interactions

NIFK MAP1B CAPZB PKM KDM3B HSPA1A HSPA1B RBM34

9.87e-05379778int:DNAJB6
InteractionHSF1 interactions

ARFGAP2 ABCF1 NOP56 CARMIL1 ETFB PKM OLA1 HSPA1A PRPF40A TOP2A

1.05e-046097710int:HSF1
InteractionADAR interactions

KRAS NIFK CAPZB ZNF318 HSPA1A TOP2A TOP2B

1.11e-04286777int:ADAR
InteractionZC3H10 interactions

KRAS NIFK TRMT6 NOP56 PRPF40A RBM34

1.17e-04200776int:ZC3H10
InteractionNBPF20 interactions

KRAS NBPF20

1.43e-045772int:NBPF20
InteractionEPRS1 interactions

HSPD1 KRAS ARFGAP2 TXLNA TRMT6 MAP1B RBBP6 CAPZB HSPA1A

1.45e-04513779int:EPRS1
InteractionRBM39 interactions

HSPD1 KRAS RAB10 NIFK NOP56 MAP1B CAPZB PKM HSPA1A HSPA1B PRPF40A TOP2A TOP2B

1.48e-0410427713int:RBM39
InteractionSRFBP1 interactions

KRAS NIFK NOP56 PLCD1

1.66e-0472774int:SRFBP1
InteractionTLE2 interactions

HSPD1 RAB10 HSPA1A HSPA1B TOP2A

1.74e-04136775int:TLE2
InteractionUBE2I interactions

KRAS ARFGAP2 TXLNB NOP56 RBBP6 SETBP1 KAT6B PRPF40A TOP2A TOP2B

1.87e-046547710int:UBE2I
InteractionCCDC8 interactions

HSPD1 KRAS ABCF1 NOP56 MAP1B CAPZB PKM ZNF318 ATXN10 TOP2A

1.92e-046567710int:CCDC8
InteractionSRP54 interactions

STIM1 KRAS CAPZB HSPA1A TOP2A

2.06e-04141775int:SRP54
InteractionPML interactions

HSPD1 KRAS UBN1 SPI1 MAP1B PKM KDM3B ZNF318 HSPA1A PRPF40A TOP2A TOP2B

2.06e-049337712int:PML
InteractionRPL23 interactions

KRAS NIFK NOP56 MAP1B FAT3 CAPZB PKM HSPA1A TOP2A

2.13e-04540779int:RPL23
InteractionNBPF14 interactions

KRAS NBPF14

2.14e-046772int:NBPF14
InteractionCHD4 interactions

HSPD1 KRAS NIFK ABCF1 NOP56 RBBP6 HSPA1A HSPA1B PRPF40A TOP2A TOP2B RBM34

2.17e-049387712int:CHD4
InteractionBTF3 interactions

HSPD1 RAB10 TXLNA TXLNB NOP56 MAP1B CAPZB PKM HSPA1A HSPA1B TOP2A

2.18e-047997711int:BTF3
InteractionDDB2 interactions

HSPD1 USP24 PKM TOP2A TOP2B

2.20e-04143775int:DDB2
InteractionSMURF1 interactions

HSPD1 RAB10 NIFK MAP1B CDK14 HSPA1A HSPA1B TOP2A RBM34

2.25e-04544779int:SMURF1
InteractionWASHC2C interactions

KRAS WASH3P WASHC1 CAPZB

2.27e-0478774int:WASHC2C
InteractionNLE1 interactions

KRAS NIFK RBBP6 TOP2A TOP2B RBM34

2.38e-04228776int:NLE1
InteractionUTP14A interactions

NIFK TRMT6 TXLNB NOP56 PRPF40A TOP2B

2.50e-04230776int:UTP14A
InteractionNEUROG3 interactions

HSPD1 KRAS NOP56 HSPA1A HSPA1B

2.66e-04149775int:NEUROG3
InteractionNACA interactions

KRAS TXLNA ETFB CAPZB KDM3B HSPA1A

2.74e-04234776int:NACA
InteractionSYT2 interactions

NRXN1 FIBP CHD9 SYT5 PRPF40A

2.74e-04150775int:SYT2
InteractionGABRA1 interactions

HSPD1 NRXN1 ATXN10 HSPA1A PRPF40A

2.92e-04152775int:GABRA1
InteractionRNF113A interactions

HSPD1 NIFK ABCF1 NOP56 RBBP6 CAPZB PKM HSPA1A PRPF40A RBM34

2.94e-046927710int:RNF113A
InteractionSYTL3 interactions

RAB10 NRXN1

2.99e-047772int:SYTL3
InteractionSHOC1 interactions

KRAS HSPA1A

2.99e-047772int:SHOC1
InteractionH2BC9 interactions

ABCF1 TRAF3IP1 MAP1B ABCA13 SETBP1 CAPZB KAT6B TOP2A

2.99e-04446778int:H2BC9
InteractionZNF330 interactions

NBPF19 NIFK TRMT6 NOP56 HSPA1A TOP2A TOP2B RBM34

2.99e-04446778int:ZNF330
InteractionWWP2 interactions

NIFK ABCF1 USP24 CAPZB PKM OLA1 HSPA1A TOP2A TOP2B RBM34 DHRS7B

3.34e-048407711int:WWP2
InteractionEFTUD2 interactions

HSPD1 STIM1 KRAS NIFK TXLNA ABCF1 NOP56 CARMIL1 USP24 CAPZB PKM OLA1 HSPA1A TOP2A TOP2B

3.35e-0414497715int:EFTUD2
InteractionHECTD1 interactions

HSPD1 NIFK TXLNA ABCF1 NOP56 MAP1B RBBP6 PRPF40A TOP2A TOP2B RBM34 AGTPBP1

3.36e-049847712int:HECTD1
InteractionTRIM31 interactions

HSPD1 NBPF19 NLRP10 NOP56 WDR87 PKM HSPA1B PRPF40A

3.37e-04454778int:TRIM31
InteractionOXR1 interactions

KRAS MAP1B HSPA1A

3.50e-0436773int:OXR1
InteractionFAM83F interactions

KRAS HSPA1A HSPA1B

3.50e-0436773int:FAM83F
InteractionRAD18 interactions

HSPD1 NOP56 RBBP6 CAPZB HSPA1A HSPA1B TOP2A TOP2B

3.52e-04457778int:RAD18
InteractionFN1 interactions

HSPD1 RAB10 ABCF1 CAPZB PKM ATXN10 OLA1 HSPA1A HSPA1B PRPF40A TOP2A

3.62e-048487711int:FN1
InteractionSRRM1 interactions

KRAS NIFK HSPA1A PRPF40A TOP2A TOP2B RBM34

3.68e-04348777int:SRRM1
InteractionCTCF interactions

HSPD1 KRAS NIFK NOP56 MAP1B PKM TOP2A TOP2B

3.73e-04461778int:CTCF
InteractionNUP62CL interactions

KRAS WASH3P WASHC1

3.79e-0437773int:NUP62CL
InteractionWASHC5 interactions

HSPD1 WASH3P WASHC1 CAPZB

3.92e-0490774int:WASHC5
InteractionTULP1 interactions

NRXN1 MAP1B

3.97e-048772int:TULP1
InteractionCEP57 interactions

KRAS TXLNA TXLNB TSPYL4 HSPA1A

4.25e-04165775int:CEP57
InteractionNFKBIL1 interactions

KRAS CHD9 TSPYL4 PRPF40A

4.45e-0493774int:NFKBIL1
InteractionPAFAH1B1 interactions

HSPD1 KRAS MAP1B CAPZB HSPA1A TOP2A

4.61e-04258776int:PAFAH1B1
InteractionPGK1 interactions

KRAS TRAF3IP1 MAP1B PKM ZNF318 HSPA1A TOP2A

5.05e-04367777int:PGK1
InteractionWASH3P interactions

WASH3P WASHC1 CAPZB

5.15e-0441773int:WASH3P
InteractionPUF60 interactions

HSPD1 KRAS NOP56 MAP1B PKM OLA1 PRPF40A

5.22e-04369777int:PUF60
InteractionDHX16 interactions

KRAS TXLNB NOP56 CAPZB TOP2A

5.28e-04173775int:DHX16
InteractionPOLR1G interactions

NIFK NOP56 FAM32A CHD9 TOP2A TOP2B RBM34 AGTPBP1

5.51e-04489778int:POLR1G
InteractionSPTY2D1 interactions

KRAS NIFK NOP56 RBM34

5.63e-0499774int:SPTY2D1
InteractionNPM1 interactions

KRAS NIFK STAB2 NOP56 MAP1B WDR87 CAPZB PKM HSPA1A HSPA1B TOP2A TOP2B RBM34

5.82e-0412017713int:NPM1
InteractionSLFN11 interactions

HSPD1 NOP56 MAP1B RBBP6 PKM POLQ TOP2A

5.83e-04376777int:SLFN11
InteractionVPS35 interactions

KRAS TRMT6 WASHC1 CAPZB PKM ZNF318

5.85e-04270776int:VPS35
InteractionRBMX2 interactions

NIFK NOP56 PRPF40A RBM34

6.08e-04101774int:RBMX2
InteractionC11orf58 interactions

HSPD1 MAP1B CEP126 HSPA1A

6.08e-04101774int:C11orf58
InteractionSRP68 interactions

KRAS NIFK NOP56 CAPZB KDM3B TOP2A RBM34

6.31e-04381777int:SRP68
InteractionH2BC18 interactions

NLRP10 MAP1B HSPA1A TOP2A RBM34

6.32e-04180775int:H2BC18
InteractionURB2 interactions

KRAS NIFK NOP56 RBM34

6.54e-04103774int:URB2
InteractionTNIP1 interactions

HSPD1 RAB10 NIFK TXLNA ABCF1 NOP56 RBBP6 CAPZB PKM HSPA1A HSPA1B PRPF40A TOP2A

6.59e-0412177713int:TNIP1
InteractionCFL1 interactions

KRAS RAB10 MAP1B CAPZB FAHD2A PKM HSPA1A

6.60e-04384777int:CFL1
InteractionPOP1 interactions

KRAS NIFK NOP56 CAPZB PRPF40A RBM34

6.69e-04277776int:POP1
InteractionRAC1 interactions

STIM1 KRAS CASKIN2 CARMIL1 ETFB CAPZB PKM FIBP HSPA1A SH3RF3 TOP2A DHRS7B

6.70e-0410637712int:RAC1
CytobandEnsembl 112 genes in cytogenetic band chr1q21

NBPF19 NBPF12 NBPF9 NBPF10 NBPF14 NBPF20

6.74e-05404786chr1q21
Cytoband1q21.1

NBPF9 NBPF10 NBPF14

1.66e-04627831q21.1
GeneFamilyNeuroblastoma breakpoint family

NBPF19 NBPF12 NBPF9 NBPF10 NBPF26 NBPF14 NBPF20

2.53e-1323527662
GeneFamilyWiskott-Aldrich Syndrome protein family

WASH6P WASH3P WASHC1 WASH2P

1.08e-071652414
GeneFamilyTopoisomerases

TOP2A TOP2B

1.21e-0465221050
GeneFamilyHeat shock 70kDa proteins

HSPA1A HSPA1B

1.07e-0317522583
CoexpressionLIN_NPAS4_TARGETS_UP

ABCF1 FAM32A RBBP6 CDK14 HSPA1A HSPA1B RBM34

1.15e-06183777MM767
CoexpressionLIN_NPAS4_TARGETS_UP

ABCF1 FAM32A RBBP6 CDK14 HSPA1A RBM34

1.18e-05172776M687
CoexpressionMURARO_PANCREAS_BETA_CELL

HSPD1 UBN1 MAP1B SETBP1 TRIQK CHD9 ZNF318 OLA1 KAT6B HSPA1A HSPA1B AGTPBP1

1.93e-059467712M39169
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

TXLNB TRAF3IP1 ABCA13 CEP126 DNAH9 CFAP157 ZBBX

4.72e-081927879cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 SYT5 CEP126 DNAH9 CFAP157 ZBBX

7.15e-071787863b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 CFAP157 ZBBX

7.63e-071807861f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

TXLNB TRAF3IP1 CEP126 DNAH9 CFAP157 ZBBX

9.53e-071877861a2178a195d078d1963947b327c6d0d4f2f48341
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

TRAF3IP1 MAP1B CEP126 DNAH9 CFAP157 ZBBX

9.83e-07188786606907c865bd2f11bb6474932716550f7723d858
ToppCell(02)_Cycling_Basal_(regeneration)-(1)_24hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

HSPD1 NOP56 PKM HSPA1A HSPA1B TOP2A

1.01e-06189786311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 SYT5 CEP126 DNAH9 CFAP157

1.08e-06191786683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.18e-061947864a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 SYT5 CEP126 CFAP157 ZBBX

1.22e-0619578679dc031258579ea328181dda33710dd897f1064a
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TRAF3IP1 ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.22e-0619578634e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.29e-0619778691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.29e-0619778622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.29e-061977863bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.29e-0619778687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

NRXN1 MAP1B ETFB CHD9 HSPA1A TOP2B

1.33e-06198786de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYT5 CEP126 DNAH9 CFAP157 ZBBX

6.26e-06148785d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYT5 CEP126 DNAH9 CFAP157 ZBBX

6.26e-06148785c8e93b87212f55774223caa385859c566fa1981f
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYT5 CEP126 DNAH9 CFAP157 ZBBX

7.60e-061547859ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYT5 CEP126 DNAH9 CFAP157 ZBBX

7.60e-0615478558072ce422d09f2de602580325eaac6c4ec6c136
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ABCA13 WDR87 DNAH9 CFAP157 ZBBX

1.03e-051647850e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.19e-0516978514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

MAP1B ABCA13 CEP126 CFAP157 ZBBX

1.30e-05172785187ae91148d293537afc77e10da2b64302322224
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.33e-05173785c3762655caa79ac4879876f470d32578a3c93b01
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TXLNB ABCA13 CEP126 DNAH9 CFAP157

1.45e-05176785dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

TRAF3IP1 MAP1B DNAH9 CFAP157 ZBBX

1.62e-05180785d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.70e-05182785fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

MAP1B CEP126 DNAH9 CFAP157 ZBBX

1.70e-05182785e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 NRXN1 ABCA13 FAT3 DNAH9

1.80e-051847852cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 NRXN1 ABCA13 FAT3 DNAH9

1.80e-05184785ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 NRXN1 ABCA13 FAT3 DNAH9

1.80e-051847852b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.84e-0518578518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MAP1B CEP126 DNAH9 CFAP157 ZBBX

1.94e-051877856fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

MAP1B CEP126 DNAH9 CFAP157 ZBBX

1.99e-0518878526326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

1.99e-051887852b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-kidney-T-cells-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

HSPD1 THEMIS POLQ HSPA1A HSPA1B

1.99e-0518878515484c05cb496cd98ed3f79a6134c5cec8f09a4d
ToppCellCOPD-Myeloid-cMonocyte|COPD / Disease state, Lineage and Cell class

NBPF19 NBPF10 NBPF26 NBPF14 AGTPBP1

2.04e-05189785d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.04e-0518978568a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellEpithelial-D_(Ciliated)|World / shred on cell class and cell subclass (v4)

TRAF3IP1 SYT5 DNAH9 CFAP157 ZBBX

2.04e-051897850bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 CFAP157

2.04e-05189785b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.04e-05189785b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

NBPF19 SETBP1 NBPF26 NBPF14 AGTPBP1

2.10e-05190785ed978cd5d9da87b49878a330e362762c487f849f
ToppCellEpithelial_cells-Ciliated_cells-A|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MAP1B CEP126 DNAH9 CFAP157 ZBBX

2.10e-05190785549d813a8f23b175875e53347928941f143e236c
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3IP1 SYT5 DNAH9 CFAP157 ZBBX

2.10e-05190785088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1B CEP126 DNAH9 CFAP157 ZBBX

2.10e-05190785a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3IP1 SYT5 DNAH9 CFAP157 ZBBX

2.10e-0519078535248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MAP1B CEP126 DNAH9 CFAP157 ZBBX

2.10e-05190785426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3IP1 SYT5 DNAH9 CFAP157 ZBBX

2.10e-051907855f5206f9e725070d865f4c891ff08bb750e58582
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-051917857b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIM1 CHD9 OLA1 PRPF40A TOP2B

2.15e-0519178560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-051917859f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3IP1 SYT5 DNAH9 CFAP157 ZBBX

2.15e-05191785bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-05191785fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3IP1 SYT5 DNAH9 CFAP157 ZBBX

2.15e-051917856880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCellHealthy_Control-Epithelial-Epithelial-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-0519178528caedb2e448e0c7f494100d714fa7cdcf150691
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-05191785b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-05191785c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-051917855129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-05191785df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellHealthy_Control-Epithelial-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-0519178515b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.15e-05191785e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class (2021.01.30)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-05191785b78547dae8328244a47c83346447bdd787efbcae
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.15e-051917859d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIM1 CHD9 OLA1 PRPF40A TOP2B

2.15e-0519178509db184cb90fe282a14474d7217068c58092c6f8
ToppCellHealthy_Control-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-05191785fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-05191785c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class (2021.01.30)

MAP1B ABCA13 DNAH9 CFAP157 ZBBX

2.15e-05191785cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIM1 CHD9 OLA1 PRPF40A TOP2B

2.15e-05191785973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.15e-051917851c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3IP1 SYT5 DNAH9 CFAP157 ZBBX

2.20e-05192785b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3IP1 SYT5 DNAH9 CFAP157 ZBBX

2.20e-051927852d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 ZBBX

2.26e-05193785e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.26e-05193785ea345d34440b25f65358a53dc72831998d1c3620
ToppCellILEUM-inflamed-(2)_B_cell-(2)_Memory_B_cells|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HSPD1 CAPZB PKM HSPA1A HSPA1B

2.26e-05193785a2ca508b1a6184579083f59419f4701c28d379ab
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1B CEP126 DNAH9 CFAP157 ZBBX

2.26e-051937850b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellLAM-Epithelial-AirwayEpi|Epithelial / Condition, Lineage and Cell class

MAP1B CEP126 DNAH9 CFAP157 ZBBX

2.26e-05193785f2672d2c495ee12c3b7d132452bde581fa5a7856
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.32e-0519478543be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 ZBBX

2.37e-05195785649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 SYT5 CEP126 ZBBX

2.37e-05195785d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 ZBBX

2.37e-05195785129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 CEP126 DNAH9 ZBBX

2.37e-051957853e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 SYT5 CEP126 ZBBX

2.37e-051957856365e3893e38231090ec2dbef010dec71dea3d07
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRXN1 MAP1B FAT3 CARMIL1 CDK14

2.37e-051957852e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.49e-0519778518fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 CEP126 DNAH9 CFAP157 ZBBX

2.49e-05197785d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

NOP56 MAP1B RBBP6 PRPF40A TOP2A

2.49e-051977850fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYT5 DNAH9 TOP2A CFAP157 ZBBX

2.55e-05198785f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

TRAF3IP1 CEP126 DNAH9 CFAP157 ZBBX

2.55e-051987856d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 ABCA13 DNAH9 CFAP157 ZBBX

2.55e-05198785d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

INHBA ABCA13 POLQ HSPA1A TOP2A

2.61e-05199785e222b90caf45904d8f763574e7b6aac13333df92
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|bone_marrow / Manually curated celltypes from each tissue

FADS1 SPI1 PKM POLQ TOP2A

2.61e-05199785961666a677589c65f733f7262822689101d39ae3
ToppCellSigmoid-T_cell-Th1|T_cell / Region, Cell class and subclass

HSPD1 NBPF19 CHD9 HSPA1A HSPA1B

2.68e-05200785bc9433a8ec3a6f10816730a32b821c63d78e6e87
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYT5 CEP126 DNAH9 CFAP157 ZBBX

2.68e-05200785cf191104484bfb2b9f87de416b9453135f8833c1
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.68e-05200785f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellBiopsy_Control_(H.)-Epithelial-Differentiating_Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.68e-05200785a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYT5 CEP126 DNAH9 CFAP157 ZBBX

2.68e-05200785a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYT5 CEP126 DNAH9 CFAP157 ZBBX

2.68e-052007854992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.68e-05200785f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.68e-05200785d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Activated_fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

INHBA CAPZB PKM HSPA1A HSPA1B

2.68e-052007852518d1758e2730b028270e76b949cebbeb7fb5ce
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 CEP126 DNAH9 CFAP157 ZBBX

2.68e-05200785cf59110547cc66b5f4a2999735336b0309ba9b0d
ComputationalNeighborhood of TERF2IP

KRAS ARFGAP2 UBN1 CAPZB KDM3B

1.16e-04116455MORF_TERF2IP
DrugPesticides

HSPD1 NBPF12 NBPF9 NBPF10 PKM NBPF14 NBPF20

5.82e-07150747ctd:D010575
DrugDexrazoxane

TOP2A TOP2B

1.04e-052742DB00380
DrugF14512

TOP2A TOP2B

1.04e-052742ctd:C534191
DrugDaunorubicin

TOP2A TOP2B

1.04e-052742DB00694
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA

KRAS UBN1 RBBP6 KAT6B PRPF40A TOP2A

2.42e-05177746985_DN
DiseaseDisease Exacerbation

KRAS ARFGAP2 ABCF1 NOP56 ABCA13 TOP2A

1.92e-06165666C0235874
Diseaseacute myeloid leukemia (implicated_via_orthology)

SPI1 TOP2A TOP2B

2.32e-0612663DOID:9119 (implicated_via_orthology)
DiseaseB cell deficiency (implicated_via_orthology)

TOP2A TOP2B

4.93e-062662DOID:2115 (implicated_via_orthology)
DiseaseMyeloid Leukemia

SPI1 SETBP1 TOP2B

8.51e-0618663C0023470
DiseaseLeukemia, Monocytic, Chronic

SPI1 SETBP1 TOP2B

8.51e-0618663C0023466
DiseaseCarcinoma, Pancreatic Ductal

KRAS HSPA1A HSPA1B

2.09e-0524663C0887833
Diseasegraft-versus-host disease (biomarker_via_orthology)

HSPA1A HSPA1B

4.91e-055662DOID:0081267 (biomarker_via_orthology)
DiseaseMajor depression, single episode

HSPA1A HSPA1B

1.76e-049662C0024517
DiseaseUterine Neoplasms

KRAS INHBA

1.76e-049662C0042138
DiseaseUterine Cancer

KRAS INHBA

2.19e-0410662C0153567
DiseaseSemantic-Pragmatic Disorder

NRXN1 SETBP1

2.68e-0411662C0454655
DiseaseAuditory Processing Disorder, Central

NRXN1 SETBP1

2.68e-0411662C0751257
DiseaseLanguage Delay

NRXN1 SETBP1

2.68e-0411662C0023012
DiseaseLanguage Development Disorders

NRXN1 SETBP1

2.68e-0411662C0023014
DiseaseSpeech Delay

NRXN1 SETBP1

2.68e-0411662C0241210
DiseaseHereditary Diffuse Gastric Cancer

HSPD1 KRAS ARFGAP2 FADS1 NOP56

5.08e-04293665C1708349
DiseaseStomach Neoplasms

HSPD1 KRAS ARFGAP2 FADS1 NOP56

5.41e-04297665C0038356
DiseaseMalignant neoplasm of stomach

HSPD1 KRAS ARFGAP2 FADS1 NOP56

5.66e-04300665C0024623
Diseaseeicosapentaenoate EPA; 20:5n3 measurement

FADS1 CDK14

6.56e-0417662EFO_0021049
DiseaseMultiple congenital anomalies

NRXN1 SETBP1

6.56e-0417662C0000772
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

NRXN1 USP24

8.22e-0419662OBA_2045199
DiseaseJuvenile Myelomonocytic Leukemia

KRAS SETBP1

8.22e-0419662C0349639
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

FADS1 USP24

1.11e-0322662EFO_0009312
DiseaseNoonan Syndrome

KRAS KAT6B

1.32e-0324662C0028326
Diseasecomplement C4b measurement

HSPA1A HSPA1B

1.43e-0325662EFO_0008092
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

FADS1 USP24

1.55e-0326662OBA_2045191
Diseasephospholipids:total lipids ratio

FADS1 ETFB USP24 MSL2

1.69e-03227664EFO_0020946
Diseasehypertension (biomarker_via_orthology)

HSPD1 FADS1 PKM PLCD1

1.69e-03227664DOID:10763 (biomarker_via_orthology)
Diseasesensory perception of smell

STAB2 THEMIS

1.92e-0329662GO_0007608
Diseasehypertrophic cardiomyopathy (implicated_via_orthology)

STIM1 KRAS

1.92e-0329662DOID:11984 (implicated_via_orthology)
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

FADS1 CARMIL1 ETFB MSL2

2.17e-03243664EFO_0004612, EFO_0020944

Protein segments in the cluster

PeptideGeneStartEntry
KKLKELKAGGKSTKQ

ABCF1

556

Q8NE71
KKVGFEVEKKGEKLI

ATXN10

451

Q9UBB4
SIVKLLKLVKKVSGK

ABCA13

2521

Q86UQ4
SIIGKKKPAAAKKGL

ARFGAP2

211

Q8N6H7
KGKSKVNGKLVALKV

CDK14

151

O94921
KKVGRKGVITVKDGK

HSPD1

191

P10809
VILIKKAGDGSKKIK

CAPZB

131

P47756
KIGPKDKKFGVKARI

AGTPBP1

141

Q9UPW5
SVSKAGKELEVKKKG

CFAP157

6

Q5JU67
VKKKGGKKEPVVAVE

CFAP157

16

Q5JU67
GASLVLLGKKKKKEE

INHBA

251

P08476
KGQVLRKKKKKVSGT

NIFK

206

Q9BYG3
ISKEEKTPGCVKIKK

KRAS

171

P01116
FKIKTVELQGKKIKL

RAB10

46

P61026
LFIGEKAVLLKTKKK

RBM34

401

P42696
KLEKVAVRGGDKKLK

OLA1

166

Q9NTK5
KVNKKTKGLIDGLTK

KAT6B

426

Q8WYB5
KIASKITKELKTGGK

KIAA1107

101

Q9UPP5
SKKKKVLLGVGDPKI

NOP56

86

O00567
RIKEVKGALKKVLAK

OR2G2

296

Q8NGZ5
KHGGLVKKILETKKD

TRAF3IP1

536

Q8TDR0
VAAGKPKEKGKIKVI

MAP1B

771

P46821
KIKVIKKEGKAAEAV

MAP1B

781

P46821
KTIKCAKTIVKGKEG

LYZL4

106

Q96KX0
GEKEAVKVVLKGLKV

NLRP10

66

Q86W26
EGLKGKISEADKKKV

HSPA1B

556

P0DMV9
VLKDVSKVKKLKQSG

KDM3B

881

Q7LBC6
KVLGEKGKNIKIISK

PKM

256

P14618
ELAVVIGKKGKHIKA

FAHD2A

161

Q96GK7
MGSGTIKIKALLKKV

NRXN1

556

Q9ULB1
GILKKDKAVKEKIPS

MSL2

426

Q9HCI7
KLVAKVKATKTKLLG

CASKIN2

21

Q8WXE0
AKKIKLNRETGKKIG

RBBP6

1206

Q7Z6E9
LKGKILLKGKKLGGL

PLCD1

431

P51178
KKIIKDILKDKGFVV

PRPF40A

676

O75400
KTKIGKLIITLGKKQ

CHD9

591

Q3L8U1
ELAVVIGKKGKHIKA

FAHD2B

161

Q6P2I3
GVAELGVTKRKKKKK

FAM32A

16

Q9Y421
TKEKGAEIPKTIKKL

CEP126

616

Q9P2H0
VKLSVKLKVKVKIGA

POLQ

2566

O75417
KLAEKLLIKAKANGK

FAT3

691

Q8TDW7
KGPIKDLIKAKGKEL

C17orf80

56

Q9BSJ5
LGKILSVELGKQKKK

FADS1

241

O60427
IKDVIGRKIKISVKK

CARMIL1

16

Q5VZK9
IKKSESGLLKKVEKG

DNAH9

1126

Q9NYC9
VLAAVGKKKKDVILA

DHRS7B

276

Q6IAN0
EGLKGKISEADKKKV

HSPA1A

556

P0DMV8
EVLGKKLSKGTKKDL

FIBP

106

O43427
VHLLQGGKKVRKKKT

SYT5

281

O00445
GKLIEVVKKKNKAGV

TOP2B

356

Q02880
SLDVGEIEKKGKGKK

NBPF9

821

P0DPF3
SLDVGEIEKKGKGKK

NBPF10

821

Q6P3W6
SLDVGEIEKKGKGKK

NBPF10

2041

Q6P3W6
SLDVGEIEKKGKGKK

NBPF10

3261

Q6P3W6
SLDVGEIEKKGKGKK

NBPF12

1336

Q5TAG4
SLDVGEIEKKGKGKK

NBPF14

481

Q5TI25
SLDVGEIEKKGKGKK

NBPF19

1526

A0A087WUL8
SLDVGEIEKKGKGKK

NBPF19

2746

A0A087WUL8
SLDVGEIEKKGKGKK

NBPF20

206

P0DPF2
SLDVGEIEKKGKGKK

NBPF20

1426

P0DPF2
SLDVGEIEKKGKGKK

NBPF20

2646

P0DPF2
SLDVGEIEKKGKGKK

NBPF20

3866

P0DPF2
SLDVGEIEKKGKGKK

NBPF20

5086

P0DPF2
SLDVGEIEKKGKGKK

NBPF26

781

B4DH59
AKKKKIEVIKPGDLG

ETFB

201

P38117
GKTGEVKKVKKKLTY

SPI1

236

P17947
KQLLVAKEGAEKIKK

STIM1

371

Q13586
KCIDGKKVGKELTEK

ALG8

126

Q9BVK2
GEVIKITGLKVKKII

THEMIS

46

Q8N1K5
KKEKKSGLLKLLAGA

SH3RF3

716

Q8TEJ3
IEKIKGSKKAIKVFS

WASH2P

76

Q6VEQ5
IEKIKGSKKAIKVFS

WASHC1

76

A8K0Z3
KKVVQKEKKVAGGVK

TSPYL4

176

Q9UJ04
IEKIKGSKKAIKVFS

WASH3P

76

C4AMC7
KLHGGKKKVKIIQGD

STAB2

476

Q8WWQ8
KDKKAAKTLGIVIGV

TAAR2

256

Q9P1P5
IKALKDKGIKGEEIV

TRMT6

111

Q9UJA5
KLVDVVKKKNKGGVA

TOP2A

336

P11388
TKLVKKGEKKGLFVE

USP24

2096

Q9UPU5
KSPKKRKLKEGGEKI

UBN1

186

Q9NPG3
KKKKIVKYGMGGLII

PIEZO1

2166

Q92508
QKLEKKILKGLGKEA

TXLNB

131

Q8N3L3
KVGKLGVLDKKTIKT

SETBP1

651

Q9Y6X0
KLKAEAKKTAIGIKE

TRIQK

36

Q629K1
EEKLAKKGGKLAEVK

WDR87

1676

Q6ZQQ6
KTEAGKAKPIKIKLS

ZNF318

1311

Q5VUA4
KAKPIKIKLSGKTVV

ZNF318

1316

Q5VUA4
AKIEKIKGSKKAIKV

WASH6P

56

Q9NQA3
KFSAGKVKLKLLKEQ

ZBBX

91

A8MT70
EKKKAKGLGKEITLL

TXLNA

161

P40222