Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA-3'-phosphate cyclase activity

RTCA RCL1

7.73e-062562GO:0003963
GeneOntologyMolecularFunctionligase activity, forming phosphoric ester bonds

RTCA RCL1

1.61e-047562GO:0016886
Domain-

RTCA RCL1

8.51e-0625523.65.10.20
DomainRNA3'-term_phos_cycl_insert

RTCA RCL1

8.51e-062552IPR013791
DomainRTC_insert

RTCA RCL1

8.51e-062552PF05189
DomainRNA3'_term_phos_cyc

RTCA RCL1

8.51e-062552IPR000228
DomainRNA3'_phos_cyclase_dom

RTCA RCL1

8.51e-062552IPR023797
DomainRTC

RTCA RCL1

8.51e-062552PF01137
DomainRNA3'_term_phos_cycl-like_CS

RTCA RCL1

8.51e-062552IPR020719
DomainRTC

RTCA RCL1

8.51e-062552PS01287
DomainRNA3'P_cycl/enolpyr_Trfase_a/b

RTCA RCL1

2.55e-053552IPR013792
DomainCRAL_TRIO_N

SEC14L3 TTPA

4.60e-0411552PF03765
DomainABC_A

ABCA5 ABCA9

5.51e-0412552IPR026082
DomainCRAL-bd_toc_tran

SEC14L3 TTPA

5.51e-0412552IPR001071
DomainCRAL_TRIO_N

SEC14L3 TTPA

5.51e-0412552SM01100
DomainCRAL/TRIO_N_dom

SEC14L3 TTPA

8.72e-0415552IPR011074
DomainCBS_dom

CNNM2 CLCN4

1.56e-0320552IPR000644
DomainCBS

CNNM2 CLCN4

1.56e-0320552PF00571
DomainCBS

CNNM2 CLCN4

1.56e-0320552PS51371
DomainCRAL_TRIO

SEC14L3 TTPA

1.72e-0321552PF00650
DomainDAPIN

AIM2 NLRP8

1.89e-0322552PS50824
DomainPYRIN

AIM2 NLRP8

1.89e-0322552PF02758
DomainDAPIN

AIM2 NLRP8

1.89e-0322552IPR004020
DomainPYRIN

AIM2 NLRP8

1.89e-0322552SM01289
DomainPeptidase_M14

AGTPBP1 AGBL3

2.07e-0323552PF00246
Domain-

SEC14L3 TTPA

2.07e-03235523.40.525.10
DomainPeptidase_M14

AGTPBP1 AGBL3

2.07e-0323552IPR000834
DomainSEC14

SEC14L3 TTPA

2.45e-0325552SM00516
DomainCRAL_TRIO

SEC14L3 TTPA

2.85e-0327552PS50191
DomainCRAL-TRIO_dom

SEC14L3 TTPA

3.06e-0328552IPR001251
Pubmed

The human RNA 3'-terminal phosphate cyclase is a member of a new family of proteins conserved in Eucarya, Bacteria and Archaea.

RTCA RCL1

2.64e-0625729184239
Pubmed

Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure.

TRPM6 CNNM2

7.91e-06357234140503
Pubmed

Acute digoxin loading reduces ABCA8A mRNA expression in the mouse liver.

ABCA5 ABCA9

1.58e-05457216445568
Pubmed

The genes encoding the somatic and testis-specific isotypes of the mouse cytochrome c genes map to paralogous regions of chromosomes 6 and 2.

GAD1 CYCS

1.58e-0545728034327
Pubmed

Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.

ABCA5 ABCA9

2.63e-05557212532264
Pubmed

Modulation of Eg5 activity contributes to mitotic spindle checkpoint activation and Tat-mediated apoptosis in CD4-positive T-lymphocytes.

BUB1 CYCS

3.94e-05657224488929
Pubmed

Selection of viral capsids and promoters affects the efficacy of rescue of Tmprss3-deficient cochlea.

MYO7A POLR2A

3.94e-05657237663645
Pubmed

Gpr125 Marks Distinct Cochlear Cell Types and Is Dispensable for Cochlear Development and Hearing.

MYO7A POLR2A

3.94e-05657234395423
Pubmed

A novel subfamily of mouse cytosolic carboxypeptidases.

AGTPBP1 AGBL3

3.94e-05657217244818
Pubmed

The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.

AGTPBP1 AGBL3

3.94e-05657225103237
Pubmed

The carboxypeptidase-like substrate-binding site in Nna1 is essential for the rescue of the Purkinje cell degeneration (pcd) phenotype.

AGTPBP1 AGBL3

3.94e-05657216952463
Pubmed

Vestibular ganglion neurons survive hair cell defects in jerker, shaker, and Varitint-waddler mutants and downregulate calretinin expression.

MYO7A AGTPBP1

5.51e-05757217663432
Pubmed

Differential expression of intestinal membrane transporters in cholera patients.

TRPM6 SLC23A1

5.51e-05757217575980
Pubmed

Developmental retardation in neonates of aldehyde reductase (AKR1A)-deficient mice is associated with low ascorbic acid and high corticosterone levels.

SLC23A1 STAR

5.51e-05757233549889
Pubmed

The cellular prion protein colocalizes with the dystroglycan complex in the brain.

GAD1 SNTA1

5.51e-05757211032878
Pubmed

Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.

TRPM6 CNNM2

7.34e-05857233859252
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RPL23A GTF2I PREP SMCHD1 POLR2A RCL1 THOC2

9.33e-0565357722586326
Pubmed

Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity.

AGTPBP1 AGBL3

9.43e-05957226829768
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TRPM6 RPL23A GTF2I EIF2S3 SMCHD1 POLR2A RCL1 CYCS THOC2 HNRNPLL

9.63e-051425571030948266
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCA5 ABCA9

1.18e-041057211435397
Pubmed

Mechanism of glycyrrhizic acid inhibition of Kaposi's sarcoma-associated herpesvirus: disruption of CTCF-cohesin-mediated RNA polymerase II pausing and sister chromatid cohesion.

GTF2I POLR2A

1.18e-041057221880767
Pubmed

IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development.

AGTPBP1 AGBL3

1.72e-041257228794449
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

RPL23A CNNM2 GTF2I PREP SMCHD1 GID8 HNRNPLL SNTA1

1.80e-0497457828675297
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

RPL23A MYO7A EIF2S3 SMCHD1 SPAG17 AGTPBP1

1.92e-0451357625798074
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RPL23A GTF2I EIF2S3 SMCHD1 POLR2A RCL1 CYCS THOC2

2.00e-0498957836424410
Pubmed

The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue.

RPL23A SPAG17 AGTPBP1

3.02e-047957325921334
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

PPT1 MYO7A SMCHD1 POLR2A GID8

3.03e-0435857532460013
Pubmed

Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis.

GAD1 AGTPBP1

4.43e-041957229474907
Pubmed

PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.

RPL23A SMCHD1 POLR2A THOC2

4.49e-0421757431685992
Pubmed

In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.

RPL23A EIF2S3 HNRNPLL

4.88e-049357325211037
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCA5 ABCA9

5.97e-04225728894702
Pubmed

Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.

AGTPBP1 AGBL3

7.73e-042557229593216
Pubmed

The DNA sequence of human chromosome 7.

GTF2I CYCS GNA12 AGBL3 DNAH11

7.80e-0444157512853948
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

GTF2I EIF2S3 POLR2A PLA2G4A

8.34e-0425657433397691
Pubmed

Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory.

GAD1 MYO7A

9.02e-042757230344048
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

GTF2I EIF2S3 SMCHD1 POLR2A RCL1 CYCS THOC2

9.16e-0495457736373674
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

RPL23A GTF2I PPT1 EIF2S3 RCL1

1.17e-0348357536912080
Pubmed

Placing the HIRA histone chaperone complex in the chromatin landscape.

GTF2I POLR2A

1.19e-033157223602572
Pubmed

UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.

EIF2S3 RTCA CYCS SPAG17 THOC2

1.26e-0349157536273042
Pubmed

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.

POLR2A RTCA RCL1

1.26e-0312957328973437
Pubmed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

MPV17 GAD1 PDE9A ACMSD HNRNPLL STAR

1.33e-0374257626871637
Pubmed

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.

SMCHD1 THOC2

1.43e-033457224270157
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RPL23A EIF2S3 SMCHD1 RCL1 THOC2 AGTPBP1

1.49e-0375957635915203
Pubmed

Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.

AGTPBP1 AGBL3

1.52e-033557237890489
Pubmed

Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.

MYO7A POLR2A

1.52e-033557232907846
GeneFamilyATP binding cassette subfamily A

ABCA5 ABCA9

3.08e-0414342805
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17 SLC23A1 DNAH11

1.38e-0718956602c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17 SLC23A1 DNAH11

1.38e-07189566164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17 SLC23A1 DNAH11

1.38e-07189566a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 GTF2I ABCA5 ABCA9

1.66e-07195566a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5 ABCA9

1.76e-061605658bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5 ABCA9

1.76e-061605652d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT2 CLCN4 PTPRE PPT1 SPAG17

2.59e-06173565d13ae4046a25ee0fb492ddedf44583a879a432e9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5 ABCA9

2.59e-061735654bc6d93716f093b460c8b047199db8cab5fea720
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 NT5DC4 ABCA5

2.89e-06177565dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP92 ABCA5 TTC21A SPAG17 DNAH11

2.97e-061785653b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5 ABCA9

3.22e-06181565e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 GTF2I ABCA5

3.40e-061835652f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 GIPC2 TTC21A SPAG17 DNAH11

3.78e-061875651bba994aaaa9825b54aaeaff3829850267bc4602
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 GIPC2 TTC21A SPAG17 DNAH11

3.78e-06187565d6ac351e7aeba98851d308c14ac395044fe4fbbb
ToppCellPND10-Epithelial-Epithelial_Airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17 SLC23A1

3.98e-06189565407d8a59969d83f014600aae1a55092283a13970
ToppCelldistal-Hematologic-Platelet/Megakaryocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEC14L3 CFAP92 SPAG17 SLC23A1 DNAH11

4.87e-06197565751ffb8792058384079ebfe94872b3525f1aea84
ToppCelldistal-Hematologic-Platelet/Megakaryocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEC14L3 CFAP92 SPAG17 SLC23A1 DNAH11

4.87e-06197565e28b1b154d9588dce07c123b36f7f01fa90a5fc1
ToppCell3'-Adult-LargeIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM6 HHLA2 PDE9A ABCA5 CYCS

5.25e-06200565156a949b3b59fb2b00e4f4a8933169f247a5f660
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PIGN POLR2A AGTPBP1 GPR107

4.22e-05154564ba55a63cfa5e0fb9dfec794f80078a2f0d03d0ad
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIPC2 TTC21A HERC6 STAR

5.14e-0516256475df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

HHLA2 TTC21A SPAG17 DNAH11

5.27e-0516356443194c6127df1ce3d29242f719645de3c11fd7c0
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 TRPM6 GIPC2 ABCA5

5.65e-0516656411b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 TRPM6 GIPC2 ABCA5

5.65e-05166564fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

SEC14L3 TTC21A SPAG17 DNAH11

5.79e-0516756426cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 TRPM6 GIPC2 ABCA5

5.79e-05167564bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 TRPM6 GIPC2 ABCA5

5.79e-051675649f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLCN4 PTPRE PPT1 AIM2

6.06e-05169564da3485d77bb7876fad4f166f6099e681b27457ae
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCN4 PTPRE PPT1 AIM2

6.34e-051715641018d7bd378ce20bee56a77d5851b3538c55098c
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)-DC1_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCN4 PTPRE PPT1 AIM2

6.34e-051715646bda333bb751d7835a04f21ac959eea79f2516aa
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCN4 PTPRE PPT1 AIM2

6.34e-05171564173bb5318fdbaef6e695b6f9e3e0ff4a5432a1a4
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLA2G4A GNA12 HERC6 ENKD1

6.49e-051725648a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CNNM2 ABCA5 ABCA9

6.63e-051735640c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SEC14L3 GIPC2 TTC21A SPAG17

6.78e-05174564f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SEC14L3 GIPC2 TTC21A SPAG17

6.94e-05175564c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 GAD1 SPAG17 DNAH11

7.09e-05176564ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7A SLC23A1 ENKD1 DNAH11

7.09e-051765643766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7A SLC23A1 ENKD1 DNAH11

7.09e-05176564aa1bada2175d8370fc71939a607407155259d195
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

SMCHD1 TTC21A HERC6 AIM2

7.57e-05179564af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5

8.07e-051825645f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HHLA2 TTC21A SPAG17 DNAH11

8.60e-051855645e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellP15-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEC14L3 GIPC2 PTPRE ABCA5

8.78e-05186564521e6e007bbae73e7328153aa170cf04ca3c1093
ToppCellPND14-Epithelial-Epithelial_Airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17

8.96e-051875641399c703505211c510b3f14c7a2aa9930566c473
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5

9.15e-05188564bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

TRPM6 CNNM2 ABCA5 ABCA9

9.15e-05188564df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5

9.15e-05188564eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRPM6 GAD1 PDE9A ABCA5

9.15e-051885641d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 TTC21A SPAG17 SLC23A1

9.34e-05189564057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5

9.34e-05189564f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17

9.34e-05189564fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

HHLA2 TTC21A SPAG17 DNAH11

9.34e-05189564a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 GIPC2 SPAG17 DNAH11

9.34e-051895641c28ad1263891d963e483b6847d8e89cc1b2d07e
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 GIPC2 TTC21A SPAG17

9.34e-05189564a28e0922e10013ae79266f6a3f9305e6ee614d8b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5

9.34e-05189564977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 GIPC2 SPAG17 DNAH11

9.34e-0518956400b20c2ed7876486c8e42e3a5b13023f44987a34
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 TTC21A SPAG17 SLC23A1

9.34e-0518956438cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 TTC21A SPAG17 SLC23A1

9.34e-051895649f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17

9.34e-05189564565063f9e3dd79164321f8a394bd12c176baf202
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17

9.34e-05189564497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 TTC21A SPAG17 SLC23A1

9.34e-05189564e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 GIPC2 SPAG17 DNAH11

9.53e-0519056473ac7be02742ee6cb003600631f6a03eecbf2083
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5

9.53e-05190564b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17

9.53e-05190564088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17

9.53e-0519056435248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 GIPC2 TTC21A SPAG17

9.53e-051905645f5206f9e725070d865f4c891ff08bb750e58582
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5

9.53e-05190564e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 TTC21A SPAG17 SLC23A1

9.73e-05191564bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 TTC21A SPAG17 SLC23A1

9.73e-051915646880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HHLA2 SPAG17 SLC23A1 DNAH11

9.73e-05191564e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCelldroplet-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 TRPM6 GIPC2 SPAG17

9.73e-051915641b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 TTC21A SPAG17 SLC23A1

9.92e-05192564b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 TTC21A SPAG17 SLC23A1

9.92e-051925642d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CNNM2 ABCA5 CYCS

9.92e-0519256446ea8f4f292db70420b378c6fa3e55e99413679c
ToppCellMS-mDC1|MS / Condition, Cell_class and T cell subcluster

CLCN4 PTPRE PPT1 AIM2

1.01e-041935644d08ebf555954d6a873a4b4c4d661dc5dd8a5bcb
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SEC14L3 TTC21A SPAG17 DNAH11

1.01e-04193564ea345d34440b25f65358a53dc72831998d1c3620
ToppCellMS-mDC1-|MS / Condition, Cell_class and T cell subcluster

CLCN4 PTPRE PPT1 AIM2

1.01e-04193564ce873f20b93e3b57c9385ee10d4becebe32ada06
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5

1.01e-04193564dd9874898587fe9fd9cf2aebc2e0579dcf06944e
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 RPL23A PDE9A TTPA

1.03e-04194564550e61a40be2baa59520aaf5912bb99ad094ba15
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GAD1 CNNM2 ABCA5

1.03e-04194564f08a7618a9ccf12e4a7620235ae662a8abc521af
ToppCellControl-Myeloid-cDC1|Control / Disease, Lineage and Cell Type

CLCN4 PTPRE PPT1 AIM2

1.05e-0419556435b2fe0588877d30cbd5d3ae259fcfd959907429
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CNNM2 ABCA5 CYCS

1.05e-0419556460d08fb27469d1e247bc47b651d7023ba82cf92f
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HHLA2 TTC21A SPAG17 DNAH11

1.05e-0419556479dc031258579ea328181dda33710dd897f1064a
ToppCellMild-CD4+_T_activated|Mild / Disease group and Cell class

SMCHD1 TTC21A HERC6 HNRNPLL

1.07e-04196564daa1c3322d81e649161e889e1d78451d2d425d09
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SEC14L3 TTC21A SPAG17 DNAH11

1.10e-0419756471fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HHLA2 TTC21A SPAG17 DNAH11

1.10e-0419756474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TTC21A BUB1 SPAG17 DNAH11

1.10e-041975646e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCelldistal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFAP92 SPAG17 SLC23A1 DNAH11

1.16e-04200564f5f5a8b0e4d802d95dc42646dd5e7d7daaad72b4
ToppCell3'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM6 HHLA2 PDE9A ABCA5

1.16e-04200564ce0c259f7fa4c0aa6d00e0bb362c029e96fce19e
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

HHLA2 TTC21A SPAG17 DNAH11

1.16e-04200564ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

HHLA2 TTC21A SPAG17 DNAH11

1.16e-04200564a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HHLA2 TTC21A SPAG17 DNAH11

1.16e-04200564918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCell5'-Adult-LargeIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM6 HHLA2 PDE9A CYCS

1.16e-042005643f29823952a4303451997dd5177a51179bd20540
ToppCell5'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM6 HHLA2 PDE9A CYCS

1.16e-04200564b2fa6e44ace5897766792ed97ffafc11555175e7
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-11|TCGA-Brain / Sample_Type by Project: Shred V9

ACMSD SPAG17 DNAH11

3.04e-041045635114600bbadb5a0d31c164afd2e8c2a7865a1423
Diseaseglycylvaline measurement

GIPC2 DNAH11

9.83e-058562EFO_0021129
Diseasehyperglycemia (implicated_via_orthology)

CYCS PLA2G4A

4.72e-0417562DOID:4195 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
MLTPLFKKSKHVGIV

ABCA5

316

Q8WWZ7
IFVFLVEMGKKIPLK

AGBL3

736

Q8NEM8
AIKIFSRPKVFVKMD

ENKD1

331

Q9H0I2
IDMKLFPKGTIFTAK

BUB1

951

O43683
MSVLIKKPFLTGLVV

ABCA9

321

Q8IUA7
VMVLKAKKPFTFETQ

AIM2

156

O14862
MVAFLLKKKPDLTAI

ANKRD62

186

A6NC57
VDMKPFKVSLLTIIK

DNAH11

1111

Q96DT5
MIMGGVFEKFPKLKV

ACMSD

206

Q8TDX5
FTMKLIEPKKAFEIE

GIPC2

191

Q8TF65
FKIVVTIFTFGMKIP

CLCN4

451

P51793
KKVDILLFPMVAKVF

CFAP92

131

Q9ULG3
VVELMFKIIGPFSKK

AGTPBP1

201

Q9UPW5
LKSFFQIMFKIETKP

RCL1

331

Q9Y2P8
AFLKPILEKMFVKRS

NPS

56

P0C0P6
ILSDKDKKIFMIVIP

GPR107

361

Q5VW38
NIEKVKFMKTIPGTA

HNRNPLL

361

Q8WVV9
VPFTPIGMLKFLKKV

PTPRE

306

P23469
EPITKGDMIKFVIRK

MAGEB18

126

Q96M61
APGIGKTILAKKVMF

NLRP8

211

Q86W28
KIPMLFLFSKEGSII

EDEM3

761

Q9BZQ6
VKTKGMAAVPKLVLF

GAD1

271

Q99259
KFFKIDPSMGTLTIV

FAT2

1811

Q9NYQ8
FIKFVLIPMFETVTK

PDE9A

516

O76083
KKVIIAFGFMVPDVK

KAT14

681

Q9H8E8
LKVGVFLTPVMKYEK

HHLA2

136

Q9UM44
EFKEISFTPKKIMTL

HERC6

111

Q8IVU3
VVAPKMLVNFLVTKK

OR8J2

76

Q8NGG1
KMVEKKIPGIYVLSL

PPT1

56

P50897
VTIKFMKVDGAKELP

PREP

151

P48147
LPILLGKMKEVGKVF

NT5DC4

201

Q86YG4
IPGTKMIFVGIKKKE

CYCS

76

P99999
VKYPKMTDLSKGVIE

GID8

211

Q9NWU2
IVEHDFVIKKIPFKM

GNA12

211

Q03113
FVIKKIPFKMVDVGG

GNA12

216

Q03113
LEIIKPKLEMIGFKN

COG2

531

Q14746
IKFIIKKPEMFETAI

GTF2I

801

P78347
LKFMLIVKATKLFPV

SEC14L3

186

Q9UDX4
SMKVGEKKEVPFIFN

PLA2G4A

111

P47712
IEISMFEKGKVPKIV

SMCHD1

376

A6NHR9
RENKMPILISKIFKG

SNTA1

106

Q13424
FIPGTTKVDALKKML

MPV17

76

P39210
IIKFPLTTESAMKKI

RPL23A

76

P62750
VALFMYKPKKVVGIE

SLC35B1

151

P78383
TMFEKGPTFIKVRVV

SPAG17

1051

Q6Q759
TKMIVGEEKKFLLPF

CNNM2

241

Q9H8M5
PILFAKVVRIGKSFM

THOC2

446

Q8NI27
MPSKFKEIFSQGLVK

TRPM6

151

Q9BX84
FPIGMGIVKRITFLK

SLC23A1

546

Q9UHI7
DKVMSKVVPDVGKVF

STAR

106

P49675
AKPVFHVGFLVKTMK

POLR2A

91

P24928
TVMVFKPIVEKFGFI

RTCA

136

O00442
VFSMIKPFLTEKIKE

TTPA

206

P49638
GDYPEAIKTLKMVIK

TTC21A

586

Q8NDW8
FKVKMTQKKEVTLPF

PIGN

371

O95427
EGKLMCKPIFSKIVS

EIF2S3

306

P41091
YVVLKVDVVMKPAKI

MXRA5

2231

Q9NR99
EKIPVMTKIYETLGK

MYO7A

1066

Q13402