Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondisaccharide binding

LGALS9B LGALS9

6.60e-057362GO:0048030
GeneOntologyMolecularFunctiongalactoside binding

LGALS9B LGALS9

1.13e-049362GO:0016936
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS9B LGALS9

5.88e-0420362GO:0070492
GeneOntologyBiologicalProcessnegative regulation of natural killer cell degranulation

LGALS9B LGALS9

1.67e-054352GO:0043322
GeneOntologyBiologicalProcesspositive regulation of regulatory T cell differentiation

LGALS9B BTN2A1 LGALS9

1.95e-0531353GO:0045591
GeneOntologyBiologicalProcessskeletal system development

BMP8B ASXL2 BMP8A DMRT2 ADAMTS4 ANKH ACAN

6.58e-05615357GO:0001501
GeneOntologyBiologicalProcessregulation of natural killer cell degranulation

LGALS9B LGALS9

7.78e-058352GO:0043321
GeneOntologyBiologicalProcessregulation of regulatory T cell differentiation

LGALS9B BTN2A1 LGALS9

7.82e-0549353GO:0045589
GeneOntologyBiologicalProcessregulatory T cell differentiation

LGALS9B BTN2A1 LGALS9

1.05e-0454353GO:0045066
GeneOntologyBiologicalProcessnegative regulation of natural killer cell activation

LGALS9B LGALS9

2.90e-0415352GO:0032815
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell proliferation

LGALS9B LGALS9

2.90e-0415352GO:2000562
GeneOntologyBiologicalProcessregulation of macrophage activation

MUC5B LGALS9B LGALS9

3.49e-0481353GO:0043030
GeneOntologyBiologicalProcessdiet induced thermogenesis

BMP8B BMP8A

3.74e-0417352GO:0002024
GeneOntologyBiologicalProcessnegative regulation of leukocyte degranulation

LGALS9B LGALS9

3.74e-0417352GO:0043301
GeneOntologyBiologicalProcessregulation of oxidoreductase activity

LGALS9B SZT2 LGALS9

3.88e-0484353GO:0051341
GeneOntologyBiologicalProcessnatural killer cell degranulation

LGALS9B LGALS9

4.21e-0418352GO:0043320
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell proliferation

LGALS9B LGALS9

4.70e-0419352GO:0046642
GeneOntologyBiologicalProcesspositive regulation of defense response to bacterium

LGALS9B LGALS9

4.70e-0419352GO:1900426
GeneOntologyBiologicalProcessnegative regulation of activated T cell proliferation

BTN2A1 LGALS9

5.21e-0420352GO:0046007
GeneOntologyBiologicalProcessregulation of T cell chemotaxis

LGALS9B LGALS9

5.21e-0420352GO:0010819
GeneOntologyBiologicalProcessdefense response to bacterium

MUC5B ADAMTS4 LGALS9B IGHM LGALS9

5.69e-04405355GO:0042742
GeneOntologyBiologicalProcessregulation of natural killer cell differentiation

LGALS9B LGALS9

5.76e-0421352GO:0032823
GeneOntologyBiologicalProcessmononuclear cell differentiation

ASXL2 LGALS9B BTN2A1 IGHM IGKC LGALS9

6.57e-04640356GO:1903131
GeneOntologyBiologicalProcesspositive regulation of leukocyte differentiation

ASXL2 LGALS9B BTN2A1 LGALS9

7.27e-04242354GO:1902107
GeneOntologyBiologicalProcesspositive regulation of hemopoiesis

ASXL2 LGALS9B BTN2A1 LGALS9

7.27e-04242354GO:1903708
GeneOntologyBiologicalProcessnegative regulation of T cell proliferation

LGALS9B BTN2A1 LGALS9

7.87e-04107353GO:0042130
GeneOntologyBiologicalProcessregulation of defense response to bacterium

LGALS9B LGALS9

8.86e-0426352GO:1900424
GeneOntologyBiologicalProcesslymphocyte mediated immunity

LGALS9B GNL1 IGHM IGKC LGALS9

9.05e-04449355GO:0002449
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell proliferation

LGALS9B LGALS9

1.03e-0328352GO:2000561
GeneOntologyBiologicalProcessadaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

LGALS9B GNL1 IGHM IGKC LGALS9

1.03e-03462355GO:0002460
GeneOntologyBiologicalProcesspositive regulation of interleukin-6 production

IL17RC LGALS9B LGALS9

1.15e-03122353GO:0032755
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell proliferation

LGALS9B LGALS9

1.18e-0330352GO:0035739
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

BMP8B BMP8A LGALS9B LGALS9

1.18e-03276354GO:0007179
GeneOntologyBiologicalProcessnegative regulation of lymphocyte proliferation

LGALS9B BTN2A1 LGALS9

1.21e-03124353GO:0050672
GeneOntologyBiologicalProcessregulation of lymphocyte chemotaxis

LGALS9B LGALS9

1.26e-0331352GO:1901623
GeneOntologyBiologicalProcessnegative regulation of mononuclear cell proliferation

LGALS9B BTN2A1 LGALS9

1.26e-03126353GO:0032945
GeneOntologyBiologicalProcessnegative regulation of regulated secretory pathway

LGALS9B LGALS9

1.34e-0332352GO:1903306
GeneOntologyBiologicalProcesscorpus callosum development

SZT2 PTPRS

1.43e-0333352GO:0022038
GeneOntologyBiologicalProcessT cell chemotaxis

LGALS9B LGALS9

1.43e-0333352GO:0010818
GeneOntologyBiologicalProcessnegative regulation of leukocyte proliferation

LGALS9B BTN2A1 LGALS9

1.51e-03134353GO:0070664
GeneOntologyBiologicalProcessregulation of lymphocyte proliferation

LGALS9B BTN2A1 IGHM LGALS9

1.63e-03301354GO:0050670
GeneOntologyBiologicalProcessmacrophage activation

MUC5B LGALS9B LGALS9

1.71e-03140353GO:0042116
GeneOntologyBiologicalProcessregulation of mononuclear cell proliferation

LGALS9B BTN2A1 IGHM LGALS9

1.73e-03306354GO:0032944
GeneOntologyBiologicalProcessregulation of T cell differentiation in thymus

LGALS9B LGALS9

1.79e-0337352GO:0033081
GeneOntologyBiologicalProcesspositive regulation of T cell differentiation

LGALS9B BTN2A1 LGALS9

1.85e-03144353GO:0045582
GeneOntologyBiologicalProcessnatural killer cell differentiation

LGALS9B LGALS9

1.89e-0338352GO:0001779
GeneOntologyBiologicalProcessleukocyte differentiation

ASXL2 LGALS9B BTN2A1 IGHM IGKC LGALS9

1.93e-03789356GO:0002521
GeneOntologyBiologicalProcesslymphocyte differentiation

LGALS9B BTN2A1 IGHM IGKC LGALS9

2.00e-03537355GO:0030098
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity

LGALS9B LGALS9

2.10e-0340352GO:0045953
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell activation

LGALS9B LGALS9

2.10e-0340352GO:2000515
GeneOntologyBiologicalProcesspositive regulation of T cell migration

LGALS9B LGALS9

2.20e-0341352GO:2000406
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immunity

LGALS9B LGALS9

2.20e-0341352GO:0002716
GeneOntologyBiologicalProcessimmune response-activating signaling pathway

PTPRS BTN2A1 IGHM IGKC LGALS9

2.27e-03553355GO:0002757
GeneOntologyBiologicalProcessnatural killer cell activation involved in immune response

LGALS9B LGALS9

2.31e-0342352GO:0002323
GeneOntologyBiologicalProcesspositive regulation of macrophage activation

LGALS9B LGALS9

2.31e-0342352GO:0043032
GeneOntologyBiologicalProcessregulation of leukocyte proliferation

LGALS9B BTN2A1 IGHM LGALS9

2.33e-03332354GO:0070663
GeneOntologyBiologicalProcesspositive regulation of SMAD protein signal transduction

LGALS9B LGALS9

2.42e-0343352GO:0060391
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

BMP8B BMP8A LGALS9B LGALS9

2.43e-03336354GO:0071560
GeneOntologyBiologicalProcesspositive regulation of lymphocyte differentiation

LGALS9B BTN2A1 LGALS9

2.59e-03162353GO:0045621
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

BMP8B BMP8A LGALS9B LGALS9

2.62e-03343354GO:0071559
GeneOntologyBiologicalProcesscortical actin cytoskeleton organization

FMNL3 FMNL2

2.65e-0345352GO:0030866
GeneOntologyBiologicalProcessnegative regulation of exocytosis

LGALS9B LGALS9

2.65e-0345352GO:0045920
GeneOntologyBiologicalProcessleukocyte mediated immunity

LGALS9B GNL1 IGHM IGKC LGALS9

2.71e-03576355GO:0002443
GeneOntologyBiologicalProcesspositive regulation of immune response

LGALS9B PTPRS BTN2A1 IGHM IGKC LGALS9

2.72e-03845356GO:0050778
GeneOntologyBiologicalProcesspositive regulation of oxidoreductase activity

LGALS9B LGALS9

2.76e-0346352GO:0051353
GeneOntologyBiologicalProcessbase-excision repair

LIG3 HUWE1

2.76e-0346352GO:0006284
GeneOntologyBiologicalProcessresponse to dietary excess

BMP8B BMP8A

2.88e-0347352GO:0002021
GeneOntologyBiologicalProcessnegative regulation of leukocyte mediated cytotoxicity

LGALS9B LGALS9

2.88e-0347352GO:0001911
GeneOntologyBiologicalProcessregulation of T-helper 17 type immune response

LGALS9B LGALS9

2.88e-0347352GO:2000316
GeneOntologyBiologicalProcesspositive regulation of interleukin-10 production

LGALS9B LGALS9

3.00e-0348352GO:0032733
GeneOntologyBiologicalProcessnegative regulation of T cell activation

LGALS9B BTN2A1 LGALS9

3.02e-03171353GO:0050868
GeneOntologyBiologicalProcessimmune response-activating cell surface receptor signaling pathway

BTN2A1 IGHM IGKC LGALS9

3.09e-03359354GO:0002429
GeneOntologyBiologicalProcesspositive regulation of lymphocyte migration

LGALS9B LGALS9

3.13e-0349352GO:2000403
GeneOntologyBiologicalProcessnegative regulation of type II interferon production

LGALS9B LGALS9

3.39e-0351352GO:0032689
GeneOntologyBiologicalProcessnegative regulation of cell killing

LGALS9B LGALS9

3.52e-0352352GO:0031342
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell activation

LGALS9B LGALS9

3.52e-0352352GO:0046636
GeneOntologyBiologicalProcesspositive regulation of cell development

ASXL2 LGALS9B BTN2A1 ACAN LGALS9

3.56e-03614355GO:0010720
GeneOntologyBiologicalProcessimmune response-regulating signaling pathway

PTPRS BTN2A1 IGHM IGKC LGALS9

3.59e-03615355GO:0002764
GeneOntologyBiologicalProcesslymphocyte chemotaxis

LGALS9B LGALS9

3.65e-0353352GO:0048247
GeneOntologyBiologicalProcessregulation of alpha-beta T cell proliferation

LGALS9B LGALS9

3.65e-0353352GO:0046640
GeneOntologyBiologicalProcessregulation of activated T cell proliferation

BTN2A1 LGALS9

3.79e-0354352GO:0046006
GeneOntologyBiologicalProcessactivation of immune response

PTPRS BTN2A1 IGHM IGKC LGALS9

3.79e-03623355GO:0002253
GeneOntologyCellularComponentIgM immunoglobulin complex

IGHM IGKC

2.99e-0415362GO:0071753
MousePhenoautoimmune arthritis

LGALS9B ANKH ACAN IGHM LGALS9

4.28e-06108325MP:0002993
MousePhenojoint inflammation

LGALS9B ANKH ACAN IGHM LGALS9

1.10e-05131325MP:0002933
MousePhenoepididymis epithelium degeneration

BMP8B BMP8A

1.52e-053322MP:0004934
MousePhenoabnormal joint physiology

LGALS9B ANKH ACAN IGHM LGALS9

1.80e-05145325MP:0031169
MousePhenoabnormal Peyer's patch morphology

LGALS9B IGHM IGKC LGALS9

3.66e-0583324MP:0000696
MousePhenoabnormal gut-associated lymphoid tissue morphology

LGALS9B IGHM IGKC LGALS9

4.02e-0585324MP:0002378
MousePhenoabnormal susceptibility to autoimmune disorder

IL17RC LGALS9B BTN2A1 ACAN IGHM LGALS9

5.98e-05307326MP:0002425
MousePhenoincreased susceptibility to induced arthritis

LGALS9B IGHM LGALS9

7.39e-0536323MP:0003724
MousePhenoepididymis degeneration

BMP8B BMP8A

1.06e-047322MP:0004935
MousePhenoautoimmune response

IL17RC LGALS9B BTN2A1 ACAN IGHM LGALS9

2.48e-04398326MP:0001844
MousePhenoabnormal self tolerance

IL17RC LGALS9B BTN2A1 ACAN IGHM LGALS9

2.55e-04400326MP:0005005
MousePhenoabnormal immune tolerance

IL17RC LGALS9B BTN2A1 ACAN IGHM LGALS9

2.69e-04404326MP:0005000
MousePhenoincreased susceptibility to autoimmune disorder

LGALS9B BTN2A1 IGHM LGALS9

4.11e-04155324MP:0005350
DomainDrf_GBD

FMNL3 FMNL2

1.08e-049332PF06371
DomainFH3_dom

FMNL3 FMNL2

1.08e-049332IPR010472
DomainGTPase-bd

FMNL3 FMNL2

1.08e-049332IPR010473
DomainDrf_FH3

FMNL3 FMNL2

1.08e-049332PF06367
DomainDrf_FH3

FMNL3 FMNL2

1.08e-049332SM01139
DomainDrf_GBD

FMNL3 FMNL2

1.08e-049332SM01140
DomainGBD/FH3_dom

FMNL3 FMNL2

1.65e-0411332IPR014768
DomainGBD_FH3

FMNL3 FMNL2

1.65e-0411332PS51232
DomainInhibin_asu

BMP8B BMP8A

2.33e-0413332IPR002405
DomainGal-bind_lectin

LGALS9B LGALS9

3.13e-0415332SM00908
DomainGALECTIN

LGALS9B LGALS9

3.13e-0415332PS51304
DomainGalectin_CRD

LGALS9B LGALS9

3.13e-0415332IPR001079
DomainFH2

FMNL3 FMNL2

3.13e-0415332PS51444
DomainGal-bind_lectin

LGALS9B LGALS9

3.13e-0415332PF00337
DomainGLECT

LGALS9B LGALS9

3.13e-0415332SM00276
DomainFH2_Formin

FMNL3 FMNL2

3.13e-0415332IPR015425
DomainFH2

FMNL3 FMNL2

3.13e-0415332PF02181
DomainFH2

FMNL3 FMNL2

3.13e-0415332SM00498
DomainTGFb_propeptide

BMP8B BMP8A

1.11e-0328332PF00688
DomainTGF-b_N

BMP8B BMP8A

1.11e-0328332IPR001111
DomainTGF-beta-rel

BMP8B BMP8A

1.45e-0332332IPR015615
DomainTGFb_CS

BMP8B BMP8A

1.45e-0332332IPR017948
DomainTGFB

BMP8B BMP8A

1.94e-0337332SM00204
DomainTGF_BETA_2

BMP8B BMP8A

1.94e-0337332PS51362
DomainTGF_beta

BMP8B BMP8A

1.94e-0337332PF00019
DomainTGF-b_C

BMP8B BMP8A

1.94e-0337332IPR001839
DomainTGF_BETA_1

BMP8B BMP8A

1.94e-0337332PS00250
DomainC1-set

IGHM IGKC

4.09e-0354332PF07654
DomainIGc1

IGHM IGKC

4.39e-0356332SM00407
DomainIg_C1-set

IGHM IGKC

4.70e-0358332IPR003597
DomainIg/MHC_CS

IGHM IGKC

4.70e-0358332IPR003006
DomainIG_MHC

IGHM IGKC

5.03e-0360332PS00290
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC5B MOGS ADAMTS4 ACAN

1.72e-04143284M27275
PathwayREACTOME_RHOC_GTPASE_CYCLE

FMNL3 FMNL2 ARHGAP21

3.51e-0470283MM15597
PathwayKEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST

BMP8B BMP8A

3.93e-0415282M47824
PathwayREACTOME_RHOC_GTPASE_CYCLE

FMNL3 FMNL2 ARHGAP21

4.14e-0474283M41807
Pubmed

Galectin-9 regulates the threshold of B cell activation and autoimmunity.

LGALS9B IGHM LGALS9

4.07e-09436334369876
Pubmed

Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44.

LGALS9B IGHM LGALS9

5.65e-071636330291028
Pubmed

Global comparative transcriptome analysis of cartilage formation in vivo.

BMP8B BMP8A ACAN

5.65e-071636319272164
Pubmed

Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments.

ADAMTS4 ACAN

1.04e-06236216188468
Pubmed

A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE.

FMNL3 FMNL2

1.04e-06236231751425
Pubmed

Protein N-myristoylation is required for cellular morphological changes induced by two formin family proteins, FMNL2 and FMNL3.

FMNL3 FMNL2

1.04e-06236222790947
Pubmed

Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.

BMP8B BMP8A

1.04e-06236231940275
Pubmed

Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4).

ADAMTS4 ACAN

1.04e-06236210751421
Pubmed

ADAMTS-4_v1 is a splice variant of ADAMTS-4 that is expressed as a protein in human synovium and cleaves aggrecan at the interglobular domain.

ADAMTS4 ACAN

1.04e-06236223897278
Pubmed

The protective role of bone morphogenetic protein-8 in the glucocorticoid-induced apoptosis on bone cells.

BMP8B BMP8A

1.04e-06236221277400
Pubmed

MMP proteolysis of the human extracellular matrix protein aggrecan is mainly a process of normal turnover.

ADAMTS4 ACAN

1.04e-06236222670872
Pubmed

Heavy chain-only antibodies are spontaneously produced in light chain-deficient mice.

IGHM IGKC

1.04e-06236218086860
Pubmed

Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.

BMP8B BMP8A

1.04e-0623629463357
Pubmed

The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

1.04e-0623628682296
Pubmed

FMNL formins boost lamellipodial force generation.

FMNL3 FMNL2

1.04e-06236228327544
Pubmed

Light chain-deficient mice produce novel multimeric heavy-chain-only IgA by faulty class switching.

IGHM IGKC

1.04e-06236219561045
Pubmed

Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.

LGALS9B LGALS9

3.12e-06336216990264
Pubmed

Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.

LGALS9B LGALS9

3.12e-06336229458010
Pubmed

Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.

LGALS9B LGALS9

3.12e-06336218005988
Pubmed

Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.

LGALS9B LGALS9

3.12e-06336223585851
Pubmed

Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.

LGALS9B LGALS9

3.12e-06336224477688
Pubmed

Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.

LGALS9B LGALS9

3.12e-06336219776007
Pubmed

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

LGALS9B LGALS9

3.12e-06336229433546
Pubmed

Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.

LGALS9B LGALS9

3.12e-06336226582205
Pubmed

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.

LGALS9B LGALS9

3.12e-06336237105392
Pubmed

Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

LGALS9B LGALS9

3.12e-0633629153289
Pubmed

Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.

LGALS9B LGALS9

3.12e-06336233316546
Pubmed

Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.

LGALS9B LGALS9

3.12e-06336218974023
Pubmed

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

LGALS9B LGALS9

3.12e-0633629038233
Pubmed

Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.

LGALS9B LGALS9

3.12e-06336223144904
Pubmed

Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.

LGALS9B LGALS9

3.12e-06336229651447
Pubmed

Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

3.12e-0633629076678
Pubmed

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

LGALS9B LGALS9

3.12e-06336236479526
Pubmed

Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.

LGALS9B LGALS9

3.12e-06336228704475
Pubmed

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.

LGALS9B LGALS9

3.12e-06336221146220
Pubmed

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.

LGALS9B LGALS9

3.12e-06336223242525
Pubmed

Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.

FMNL3 FMNL2

3.12e-06336212684686
Pubmed

Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.

LGALS9B LGALS9

3.12e-06336219851072
Pubmed

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.

LGALS9B LGALS9

3.12e-06336233923930
Pubmed

Requirement of Bmp8b for the generation of primordial germ cells in the mouse.

BMP8B BMP8A

3.12e-06336210894154
Pubmed

Alarmin function of galectin-9 in murine respiratory tularemia.

LGALS9B LGALS9

3.12e-06336225898318
Pubmed

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.

LGALS9B LGALS9

3.12e-06336231937306
Pubmed

Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.

LGALS9B LGALS9

3.12e-06336221426359
Pubmed

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.

LGALS9B LGALS9

3.12e-06336231969388
Pubmed

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.

LGALS9B LGALS9

3.12e-06336223836896
Pubmed

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.

LGALS9B LGALS9

3.12e-06336218282810
Pubmed

Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs).

BMP8B BMP8A

3.12e-06336212925636
Pubmed

Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.

LGALS9B LGALS9

3.12e-06336235241678
Pubmed

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.

LGALS9B LGALS9

3.12e-0633627890611
Pubmed

Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.

LGALS9B LGALS9

3.12e-06336222341088
Pubmed

Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.

LGALS9B LGALS9

3.12e-06336228990062
Pubmed

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

LGALS9B LGALS9

3.12e-06336232380082
Pubmed

Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

LGALS9B LGALS9

3.12e-06336224083426
Pubmed

Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.

LGALS9B LGALS9

3.12e-06336223667648
Pubmed

Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.

LGALS9B LGALS9

3.12e-06336237279535
Pubmed

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.

LGALS9B LGALS9

3.12e-06336218579572
Pubmed

The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.

LGALS9B LGALS9

3.12e-06336225931247
Pubmed

BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions.

BMP8B BMP8A

3.12e-06336222579288
Pubmed

Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.

LGALS9B LGALS9

3.12e-06336222627368
Pubmed

Mutation in Bmp7 exacerbates the phenotype of Bmp8a mutants in spermatogenesis and epididymis.

BMP8B BMP8A

3.12e-06336211784057
Pubmed

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.

LGALS9B LGALS9

3.12e-06336228877989
Pubmed

Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.

LGALS9B LGALS9

3.12e-06336233153471
Pubmed

Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.

LGALS9B LGALS9

3.12e-06336219800850
Pubmed

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.

LGALS9B LGALS9

3.12e-06336222052881
Pubmed

Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.

LGALS9B LGALS9

3.12e-06336217560833
Pubmed

The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.

LGALS9B LGALS9

3.12e-06336238987795
Pubmed

Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.

LGALS9B LGALS9

3.12e-06336235643073
Pubmed

Galectin-9 functionally impairs natural killer cells in humans and mice.

LGALS9B LGALS9

3.12e-06336223408620
Pubmed

Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a.

BMP8B BMP8A

3.12e-06336225451979
Pubmed

FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42.

FMNL3 FMNL2

3.12e-06336228852060
Pubmed

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

LIG3 MOGS NUP107 NOL6

4.13e-0610436426167872
Pubmed

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis.

BMP8B BMP8A MLIP

5.44e-063336332640236
Pubmed

Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.

LGALS9B LGALS9

6.24e-06436220463811
Pubmed

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.

LGALS9B LGALS9

6.24e-06436238686388
Pubmed

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.

LGALS9B LGALS9

6.24e-06436222677125
Pubmed

Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.

LGALS9B LGALS9

6.24e-06436232855403
Pubmed

Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.

LGALS9B LGALS9

6.24e-06436223657851
Pubmed

Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.

LGALS9B LGALS9

6.24e-06436219234217
Pubmed

[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].

LGALS9B LGALS9

6.24e-06436218826117
Pubmed

The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis.

LGALS9B LGALS9

6.24e-06436224333756
Pubmed

The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.

LGALS9B LGALS9

6.24e-06436238853593
Pubmed

Characterization and chromosomal localization of PTPRO, a novel receptor protein tyrosine phosphatase, expressed in hematopoietic stem cells.

BMP8B BMP8A

6.24e-0643629434160
Pubmed

Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development.

BMP8B BMP8A

6.24e-0643628843393
Pubmed

Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.

LGALS9B LGALS9

6.24e-06436235715604
Pubmed

Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.

LGALS9B LGALS9

6.24e-06436224958847
Pubmed

Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.

LGALS9B LGALS9

6.24e-06436219017954
Pubmed

Galectin-9 binds IgM-BCR to regulate B cell signaling.

LGALS9B LGALS9

6.24e-06436230120235
Pubmed

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.

LGALS9B LGALS9

6.24e-06436233963043
Pubmed

Galectin-9: A novel promoter of atherosclerosis progression.

LGALS9B LGALS9

6.24e-06436236459823
Pubmed

[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].

LGALS9B LGALS9

6.24e-06436221575348
Pubmed

Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.

LGALS9B LGALS9

6.24e-06436218346632
Pubmed

Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge.

LGALS9B LGALS9

6.24e-06436211839756
Pubmed

Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.

LGALS9B LGALS9

6.24e-06436233107565
Pubmed

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.

LGALS9B LGALS9

6.24e-06436219670381
Pubmed

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.

LGALS9B LGALS9

6.24e-06436229611821
Pubmed

Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.

LGALS9B LGALS9

6.24e-06436230763585
Pubmed

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.

LGALS9B LGALS9

6.24e-06436225450716
Pubmed

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

LGALS9B LGALS9

6.24e-06436216286920
Pubmed

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.

LGALS9B LGALS9

6.24e-06436233727589
Pubmed

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.

LGALS9B LGALS9

6.24e-06436219362679
InteractionENPP4 interactions

IL17RC ANKH LGALS9

1.32e-0526363int:ENPP4
InteractionLUM interactions

LGALS9B ACAN LGALS9

2.51e-0532363int:LUM
CytobandEnsembl 112 genes in cytogenetic band chr1p34

SLC6A9 BMP8B BMP8A SZT2

8.26e-05294364chr1p34
Cytoband13q12

SACS PCOTH

1.63e-042436213q12
Cytoband9p13.3

PHF24 NOL6

1.60e-03753629p13.3
GeneFamilyBone morphogenetic proteins|Astacins

BMP8B BMP8A

7.02e-0511212455
GeneFamilyGalectins

LGALS9B LGALS9

1.34e-0415212629
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN

BMP8B BMP8A LGALS9B LGALS9

4.74e-05146364MM973
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_FGF3

BMP8B BMP8A

5.11e-058362M10331
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_FGF3

BMP8B BMP8A

6.56e-059362MM608
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME2_AND_H3K27ME3

BMP8B BMP8A ACAN

8.51e-0562363MM829
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3

BMP8B BMP8A DMRT2 ACAN PHF24

1.21e-04357365MM828
CoexpressionMEBARKI_HCC_PROGENITOR_FZD8CRD_UP

FMNL3 LIG3 RGS9 NUP107 SACS CDCA5

1.36e-04588366M38992
CoexpressionGSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP

DMRT2 CDCA5 IGHM IGKC

1.57e-04199364M6198
CoexpressionGSE8835_CD4_VS_CD8_TCELL_UP

LIG3 ASXL2 HUWE1 NOL6

1.60e-04200364M6254
CoexpressionGSE27786_LSK_VS_CD4_TCELL_DN

FMNL3 ASXL2 GNL1 IGKC

1.60e-04200364M4747
ToppCellmild-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FMNL3 PTPRS IGHM IGKC

1.21e-0517636459a9c262c252b7d220a025837922d98e9d6b0a24
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC6A9 BMP8B BMP8A IGKC

1.24e-051773644c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC6A9 BMP8B BMP8A IGKC

1.24e-05177364fc40918825b7e1eb6861df59dfca944778a64b98
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC6A9 BMP8B BMP8A IGKC

1.24e-05177364d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCellHealthy_donor-Plasmablast|Healthy_donor / disease group, cell group and cell class (v2)

SLC6A9 BMP8B CDCA5 IGKC

1.26e-05178364388b8b4fa20dcc6e9ae4b06118e20b2c20c52bde
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC6A9 BMP8B BMP8A IGKC

1.29e-05179364494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

ADAMTS4 PTPRS IGHM IGKC

1.38e-0518236402e04294fce12591c32d7bd0e866a000ad1f836e
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

SLC6A9 BMP8B BMP8A IGKC

1.50e-05186364e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMNL3 PTPRS IGHM IGKC

1.50e-051863640096a61b1841784c913752b4f3639200446cc02c
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

FMNL3 BMP8A ADAMTS4 ACAN

1.50e-051863641e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCellcontrol-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FMNL3 PTPRS IGHM IGKC

1.50e-05186364fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMNL3 PTPRS IGHM IGKC

1.50e-051863649e159ad7289dcae2ec7ce655df746f46801b81d3
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMNL3 PTPRS IGHM IGKC

1.50e-051863646345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMP8A CDCA5 IGHM IGKC

1.57e-051883646844cebca177fdf38b21a40d606230a033717a3a
ToppCellsevere_COVID-19-Plasmablast|World / disease group, cell group and cell class (v2)

SLC6A9 BMP8B CDCA5 IGKC

1.57e-0518836425ca19af4ac419a0f5026a6ccbd8b554b268a6f3
ToppCellhealthy_donor-Lymphocytic-Plasma_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

SLC6A9 BMP8B BMP8A IGKC

1.57e-05188364bd53b0371154cff680226897b61c9809a239d1b6
ToppCellmyeloid-pDC|myeloid / Lineage and Cell class

FMNL3 PTPRS IGHM IGKC

1.57e-05188364a2dc4bbeca2bdc00c51825dd65a699c54c72f241
ToppCellBAL-Severe-Lymphocyte-B|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BMP8B CDCA5 IGHM IGKC

1.63e-05190364e82fefea5ac03470d10463832d3efd2380895860
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BMP8B CDCA5 IGHM IGKC

1.63e-051903647fbaf46bf24d46543047582f0d262f3523e28eb4
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BMP8B CDCA5 IGHM IGKC

1.63e-051903649560722facaf3516936fcbc2a900a405fd85e5d0
ToppCellControl-pDC-|Control / Disease condition and Cell class

FMNL3 PTPRS IGHM IGKC

1.67e-051913641d7b0fae4d114d6db933c18b4eb2066ffa61356d
ToppCellControl-pDC|Control / Disease condition and Cell class

FMNL3 PTPRS IGHM IGKC

1.67e-05191364543e1437a52d04436862dd1c27b4fae95c44fcc8
ToppCellSevere-Lymphoid-Plasma-|Severe / Condition, Lineage, Cell class and cell subclass

BMP8B CDCA5 IGHM IGKC

1.70e-051923643a900d872da80b47104245440eb09b8c80b0b2b0
ToppCellSevere-Lymphoid-Plasma|Severe / Condition, Lineage, Cell class and cell subclass

BMP8B CDCA5 IGHM IGKC

1.70e-051923648d26584c7897a2c77df9efe787e7c04d1e883df9
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMP8A CDCA5 IGHM IGKC

1.70e-05192364b9c606547c303a099a653169923a44c20816a604
ToppCellHealthy-pDC|Healthy / disease group, cell group and cell class

FMNL3 PTPRS IGHM IGKC

1.70e-0519236433d695a28d22b4af111df9591830a33bb7ef7b2d
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BMP8B BMP8A IGHM IGKC

1.81e-05195364c6e31038be2463f1601d52c82efa4e9facb8228f
ToppCellmetastatic_Brain-T/NK_cells-Undetermined|T/NK_cells / Location, Cell class and cell subclass

NUP107 CDCA5 IGHM IGKC

1.84e-05196364c17e105e47446a48aa06e1a3810828e20aa56ea9
ToppCellwk_15-18-Hematologic_Lymphocytic-B-Large_pre-B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CDCA5 IGHM IGKC LGALS9

1.88e-051973647e0834b3947031bf244a10624dcf3f2095c79368
ToppCellInfluenza-Influenza_Severe-Myeloid-pDC|Influenza_Severe / Disease, condition lineage and cell class

FMNL3 PTPRS IGHM IGKC

1.88e-05197364e8e6f71e6dc8a695e4321a18543c1df63dd62f3e
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasmablast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BMP8B CDCA5 IGHM IGKC

1.92e-05198364cfbe0bae21b6cd9cd15d3e659b618b44cfe3eaec
ToppCellSepsis-Leuk-UTI-Others|Leuk-UTI / Disease, condition lineage and cell class

FMNL3 PTPRS IGHM IGKC

1.96e-05199364e45fe91f1d1c47a305b0f39d808730723852af00
ToppCellSepsis-Leuk-UTI-Myeloid-pDC|Leuk-UTI / Disease, condition lineage and cell class

FMNL3 PTPRS IGHM IGKC

1.96e-051993642f8d297afd26ae1e9fb66d8573274452c4133b6c
ToppCellSepsis-ICU-SEP-Lymphocyte-B-Plasmablast|ICU-SEP / Disease, condition lineage and cell class

SLC6A9 BMP8B CDCA5 IGKC

1.96e-0519936409f02aaedf19f895a7b6f8eb939fd346b1df75f1
ToppCellSepsis-Leuk-UTI-Others-RBC|Leuk-UTI / Disease, condition lineage and cell class

FMNL3 PTPRS IGHM IGKC

1.96e-05199364d9b517199a646c9461c615412ad5b58cf4bed7c8
ToppCellCOVID-19_Severe-NK_activated|COVID-19_Severe / Disease condition and Cell class

LGALS9B IGHM IGKC LGALS9

2.00e-05200364f1f6c7f7f75f891c9ccf6bf58f4d65b9cf10bbd8
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Macroglial-Glia_progenitor_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

BMP8B DMRT2 ACAN LGALS9

2.00e-052003646c1b7b0f3cd35d8cfee181ea83c73127dbc41ac5
ToppCell(6)_Macrophage-(60)_Macrophage|(6)_Macrophage / shred on Cell_type and subtype

ANKH IGHM IGKC

2.93e-0574363356978d2ee61e7042d7a9ad3bc744d3e7a7f76c0
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IRS4 DMRT2 IGKC

7.43e-05101363cf52c93f523c5f25bd45519a1444ce7bd1d8b577
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RGS9 IRS4 DMRT2

1.21e-04119363e868453c02dcf0e07821886b81ca739887d43c67
ToppCellBronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-ILC|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BMP8B CDCA5 IGKC

1.43e-04126363e33957cf1541733b06de9f9e7b2801b3d8ae831d
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-pDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRS IGHM IGKC

1.53e-04129363454bae525f6db3d0dd6347d2a2c3ea9dda9cd212
ToppCellLPS_only-Myeloid-Dendritic_cells-pDC|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRS IGHM IGKC

1.75e-041353630afe232aa1a1e6c37a5b3183b67d7fa07e0ea791
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-pDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRS IGHM IGKC

2.49e-041523630c6dd41142e4ca1e54ca41e05e42ed29fbf0e570
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

ACAN IGHM IGKC

2.68e-04156363afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell390C-Lymphocytic-Plasma_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

BMP8B IGHM IGKC

2.68e-041563630de2fc695bd5f8d4633c514f71ea941c88137bac
ToppCell390C-Lymphocytic-Plasma_cell-|390C / Donor, Lineage, Cell class and subclass (all cells)

BMP8B IGHM IGKC

2.68e-041563634f92ca30755430db44402afc603d1ecd8bfc3617
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA5 IGHM IGKC

2.73e-041573636730b775308f45a2f3946016bdbb7f8e5b5efe49
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-pDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRS IGHM IGKC

2.89e-04160363dee756a2dc9725520d439e7273c489c2284015d8
ToppCellMild-Lymphoid-Plasma-|Mild / Condition, Lineage, Cell class and cell subclass

PTPRS IGHM IGKC

2.89e-04160363aa79848913910c01249d6cacf4ed53ec0e4f5c3d
ToppCellMild-Lymphoid-Plasma|Mild / Condition, Lineage, Cell class and cell subclass

PTPRS IGHM IGKC

2.89e-041603637fdb849f5caf5a127a2582326215e11f8eb4fa0e
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOGS NUP107 PHF24

2.89e-041603638a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP8A IGHM IGKC

2.89e-04160363e44b3c74c76b4632ada7f5bd6d09434b02d79743
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BMP8A IGHM IGKC

3.00e-04162363ee6f05620f4f4ebbebd5b098afc7c20876e3d21f
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BMP8A IGHM IGKC

3.00e-041623639e72d468fcdd0d27b517a9e36efb35d4617a88f9
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IGHM IGKC

3.04e-0432362f9624fe102388755e72d5a9a34afebaf77127961
ToppCell356C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PTPRS IGHM IGKC

3.05e-04163363ae9c5eb19657ea94b7f2357cbc8679acd697b8fe
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC6A9 BMP8A ADAMTS4

3.05e-041633638f24cef152f5965727bbeee116bd26c75cbba82a
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA5 IGHM IGKC

3.11e-04164363249d8f75a64bce7db52ce0c563f496b9edf602a6
ToppCell343B-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PTPRS IGHM IGKC

3.11e-04164363cf62d34ce9dd220fe61748466c84fd70d9ba697c
ToppCell343B-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PTPRS IGHM IGKC

3.11e-04164363e00549bc8b3a5566f39031f39d7e698b0b107a7f
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA5 IGHM IGKC

3.16e-04165363953c8242a81a39ade63ac8e5b34fe58575771746
ToppCell-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

RGS9 IGHM IGKC

3.22e-04166363bc9323de1373fdc0357e6bb46874f6c4787443a9
ToppCellsevere-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PTPRS IGHM IGKC

3.22e-04166363ae38850fde549b8dd6fb12f0ef80b428ade50485
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

BMP8B IGHM IGKC

3.22e-041663632b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCell390C-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BMP8B IGHM IGKC

3.22e-041663634ba3711a02d3695b27f7cefd7c60e3be009f5bef
ToppCell390C-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BMP8B IGHM IGKC

3.22e-0416636335f6ae2664935dda0d883b32a050ced843204f2d
ToppCell10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

PTPRS IGHM IGKC

3.34e-0416836390f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BMP8B IGHM IGKC

3.34e-041683632ec53f91de3bff8a106430a78b81ee6870f0c55e
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHM IGKC LGALS9

3.39e-041693637fd13b6e6041032697d36dd215f6b943d4675cf2
ToppCellHealthy_Control-Lymphoid-pDC|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PTPRS IGHM IGKC

3.39e-04169363a4e9b8b2f0338203455ba941b8f99bf4884d26f0
ToppCellBAL-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

BMP8B PTPRS IGKC

3.39e-041693639ab34f602d46ce87283d243b81621e8806504f43
ToppCellBAL-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

BMP8B PTPRS IGKC

3.39e-0416936389fbafdb4628ce7a90c50398870e0f8ee90cfd91
ToppCellBAL-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BMP8B PTPRS IGKC

3.39e-0416936375d367eb35768d3063096e8866cea649dac3b1bd
ToppCellHealthy_Control-Lymphoid-pDC-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PTPRS IGHM IGKC

3.39e-04169363338ce99897cb522b86edd603f75bc15ec4dfcda3
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-stromal_related-FDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RGS9 BMP8A FMNL2

3.39e-0416936349a54fb2ea9db5c45e107f304838c536908308bb
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPRS IGHM IGKC

3.45e-0417036392e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCellBAL-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BMP8B PTPRS IGKC

3.45e-041703637dcb6319ba4d7b258dd0a17449d837800ef46ccc
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHM IGKC LGALS9

3.45e-04170363e319ab46842d028898c09d6d8f056f896edb1558
ToppCell367C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PTPRS IGHM IGKC

3.45e-04170363fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPRS IGHM IGKC

3.45e-041703639f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPRS IGHM IGKC

3.45e-04170363b49f7c8a27078de2137ed04f74cfee30729cfa5e
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA5 IGHM IGKC

3.45e-04170363e08a6c5ac34c456da8c7318f104e06fca585be1f
ToppCellBAL-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BMP8B PTPRS IGKC

3.45e-041703637377e59fba4bf97ba893ccf6b5e149b5152407be
ToppCellBAL-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BMP8B PTPRS IGKC

3.45e-04170363e18211029e9ffad54458fd921f455172aad407c7
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SACS IGHM IGKC

3.45e-0417036332917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHM IGKC LGALS9

3.51e-04171363a350a5f840e0fb0ccd29bb29cacc23a89abd8404
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHM IGKC LGALS9

3.51e-04171363e0a99ca8d4c86b58f54af7755ffd8e0ffbfae5e1
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHM IGKC LGALS9

3.51e-0417136358bdcbc65062ac09f1c014e08302f938a3e6b252
ToppCellControl-B_cell-Plasmablast|Control / Disease group,lineage and cell class (2021.01.30)

BMP8B PTPRS IGKC

3.51e-04171363c09afc4b111b2b5acca75177554f6364ee02d37c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FMNL2 IGHM IGKC

3.51e-04171363a2938e56cb5749004317798dc7ac0f0c2d4d8ae0
ToppCellCOVID-pDC|COVID / Condition, Cell_class and T cell subcluster

PTPRS IGHM IGKC

3.57e-041723633ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA5 IGHM IGKC

3.57e-0417236376c06a968d3333441eed103abef1e636a1c3e7a1
ToppCellCOVID-pDC-|COVID / Condition, Cell_class and T cell subcluster

PTPRS IGHM IGKC

3.57e-04172363a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHM IGKC LGALS9

3.63e-0417336367c342295b8a06ce38e081ba74478c568917a396
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

LIG3 ASXL2 NOL6

3.63e-04173363d11705e56b6b21eec963ea224717f27680c781ed
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5B DMRT2 LGALS9B

3.63e-04173363464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCelldroplet-Marrow-nan-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A9 BMP8B MOGS

3.63e-041733636d2ceba4f89a228600e2b40aba81bb0eb81578c0
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PTPRS IGHM IGKC

3.70e-04174363ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

MUC5B MLIP LGALS9B

3.70e-041743637d2f802f493f19a068e097b2909a9000e2160266
ComputationalGenes in the cancer module 547.

NUP107 IGHM

4.72e-0416222MODULE_547
ComputationalGenes in the cancer module 313.

NUP107 IGHM

6.70e-0419222MODULE_313
ComputationalGenes in the cancer module 240.

NUP107 IGHM

7.43e-0420222MODULE_240
ComputationalGenes in the cancer module 156.

NUP107 IGHM

9.01e-0422222MODULE_156
Diseasedegenerative disc disease (biomarker_via_orthology)

ADAMTS4 ACAN

6.63e-0511332DOID:90 (biomarker_via_orthology)
Diseasediabetes mellitus (implicated_via_orthology)

BMP8B BMP8A

3.88e-0426332DOID:9351 (implicated_via_orthology)
Diseaseazoospermia (implicated_via_orthology)

DMRT2 PTPRS

4.18e-0427332DOID:14227 (implicated_via_orthology)
Diseaseglycocholate measurement

FMNL2 NOL6

5.17e-0430332EFO_0010491
Diseaseobesity (implicated_via_orthology)

BMP8B BMP8A ADAMTS4

1.77e-03215333DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PAVQSPRRSPRISFF

CDCA5

71

Q96FF9
IRFRFRGETFPPFIV

CXorf58

101

Q96LI9
FHPSQVSPRARFPVS

ASXL2

631

Q76L83
PLIFTFVPTVRRLPT

MLIP

31

Q5VWP3
RRVSFVPPVTVFPSL

MUC5B

51

Q9HC84
PFASPSRFIRRPSTT

RGS9

506

O75916
VIPRTPSSFRQPFTP

NUP107

51

P57740
RTVPVQPAFSTVPFS

LGALS9B

151

Q3B8N2
RTVPVQPAFSTVPFS

LGALS9

151

O00182
TEVFPPTPVRPAFSF

NOL6

696

Q9H6R4
PTPVRPAFSFYETLR

NOL6

701

Q9H6R4
VVLFTSFPRDPRTPQ

GNL1

251

P36915
TRVSPIFPFSPRSPF

PCOTH

31

Q58A44
PPSTPDFSRLRRYFV

LIG3

946

P49916
TPTPRFRLTFFICSV

HUWE1

1121

Q7Z6Z7
FPSVRPFPSVELFPS

ACAN

806

P16112
PVPLFTAVPSRSFFP

MOGS

431

Q13724
RPYIAARFSVLPPTF

PTPRS

1206

Q13332
LRYSFFVPRPTPSTP

ADAMTS4

796

O75173
RSAFSPPRRNFSPIV

DMRT2

426

Q9Y5R5
AIRVFAIPPSFASIF

IGHM

221

P01871
PKTTPPSVFFPVFVR

FMNL3

906

Q8IVF7
PFVVTFFRASPSPIR

BMP8A

246

Q7Z5Y6
FFRASPSPIRTPRAV

BMP8A

251

Q7Z5Y6
LRIFSFFPVPVTVRA

ANKH

371

Q9HCJ1
PRSAFSVPVRPFFRL

BTN2A1

476

Q7KYR7
PPSVFFPVFVRFVKA

FMNL2

966

Q96PY5
RTVAAPSVFIFPPSD

IGKC

1

P01834
PFVVTFFRASPSPIR

BMP8B

246

P34820
FFRASPSPIRTPRAV

BMP8B

251

P34820
FPGTFFRFPLRLQPS

SACS

266

Q9NZJ4
PDAVPALFRTVPVFT

IL17RC

711

Q8NAC3
VSVPASFFRRLAPSP

IRS4

426

O14654
PRPFLLVPSTRVTFL

SZT2

76

Q5T011
TSRFTPPAFIRPTRK

PHF24

96

Q9UPV7
TLLPVQRSFFLPPFS

SLC6A9

31

P48067
SPRSVGPFALTVVPF

TRAPPC9

1051

Q96Q05
FPVFPTALTSERLFR

ARHGAP21

1641

Q5T5U3
VNFFRPFTRFLVPFT

TRMT10C

11

Q7L0Y3