Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	7.33e-10	279	61	11	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D HPS4 TBC1D3I ARHGEF17 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.38e-09	507	61	13	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D HPS4 TBC1D3I ARHGEF17 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.38e-09	507	61	13	GO:0030695
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BAD TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	5.70e-07	656	61	12	GO:0008047
GeneOntologyMolecularFunction	enzyme regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D HPS4 BAD TBC1D3I ARHGEF17 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	7.39e-05	1418	61	14	GO:0030234
GeneOntologyMolecularFunction	molecular function activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BAD TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.02e-04	1233	61	12	GO:0140677
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.48e-14	109	60	11	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.04e-10	244	60	11	GO:0043547
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I PLXNB2 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.93e-10	335	60	12	GO:0043087
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BAD GRIN2B TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.52e-09	499	60	13	GO:0051345
GeneOntologyBiologicalProcess	regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L MGMT TBC1D3D BAD GRIN2B TBC1D3I PLXNB2 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.15e-08	878	60	15	GO:0051336
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BAD GRIN2B TBC1D3I TBC1D3G TBC1D3C TBC1D3B AXIN1 TBC1D3K TBC1D3F	1.08e-06	1028	60	14	GO:0043085
GeneOntologyBiologicalProcess	positive regulation of molecular function	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BAD ARID5B GRIN2B TBC1D3I TBC1D3G TBC1D3C TBC1D3B AXIN1 TBC1D3K TBC1D3F	1.04e-05	1430	60	15	GO:0044093
GeneOntologyBiologicalProcess	organelle inheritance	GOLGA8B GOLGA8A VCPIP1	7.28e-05	28	60	3	GO:0048308
GeneOntologyBiologicalProcess	Golgi inheritance	GOLGA8B GOLGA8A VCPIP1	7.28e-05	28	60	3	GO:0048313
GeneOntologyCellularComponent	keratohyalin granule	HRNR FLG2	8.33e-05	5	61	2	GO:0036457
GeneOntologyCellularComponent	Golgi cis cisterna	GOLGA8DP GOLGA8B GOLGA8A	1.21e-04	33	61	3	GO:0000137
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.31e-16	49	59	10	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	7.79e-16	53	59	10	PF00566
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.16e-15	55	59	10	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.16e-15	55	59	10	IPR000195
Domain	RWD	DHX57 EIF2AK4	5.30e-04	11	59	2	PF05773
Domain	RWD-domain	DHX57 EIF2AK4	6.34e-04	12	59	2	IPR006575
Domain	GOLGA2L5	GOLGA8B GOLGA8A	1.45e-03	18	59	2	PF15070
Domain	Golgin_A	GOLGA8B GOLGA8A	1.45e-03	18	59	2	IPR024858
Domain	S100_CABP	HRNR FLG2	3.27e-03	27	59	2	PS00303
Domain	S_100	HRNR FLG2	3.27e-03	27	59	2	PF01023
Domain	S100_Ca-bd_sub	HRNR FLG2	3.52e-03	28	59	2	IPR013787
Domain	S100/CaBP-9k_CS	HRNR FLG2	3.52e-03	28	59	2	IPR001751
Domain	S_100	HRNR FLG2	3.52e-03	28	59	2	SM01394
Domain	-	ZC3H4 DHX57	7.08e-03	40	59	2	4.10.1000.10
Domain	ZnF_C3H1	ZC3H4 DHX57	1.01e-02	48	59	2	SM00356
Domain	zf-CCCH	ZC3H4 DHX57	1.05e-02	49	59	2	PF00642
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K	2.55e-11	99	46	9	M46448
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.26e-31	11	62	11	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3G TBC1D3B TBC1D3F	6.61e-11	74	62	7	16625196
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	2.16e-08	4	62	3	12359748
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	2.16e-08	4	62	3	8406013
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	5.38e-08	5	62	3	12604796
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	5.38e-08	5	62	3	8471161
Pubmed	A human MAP kinase interactome.	SHANK1 USP53 SF3B1 RBM33 HPS4 BAD MBD5 TBC1D3F	2.40e-06	486	62	8	20936779
Pubmed	Human autoantibodies to a novel Golgi protein golgin-67: high similarity with golgin-95/gm 130 autoantigen.	GOLGA8B GOLGA8A	3.13e-06	2	62	2	10677249
Pubmed	Identification and characterization of a novel Golgi protein, golgin-67.	GOLGA8B GOLGA8A	3.13e-06	2	62	2	10660574
Pubmed	Genome-wide association study supports the role of the immunological system and of the neurodevelopmental processes in response to haloperidol treatment.	ARID5B EIF2AK4	9.37e-06	3	62	2	24751813
Pubmed	Diversity of human copy number variation and multicopy genes.	TBC1D3E TBC1D3G	9.37e-06	3	62	2	21030649
Pubmed	Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.	HRNR FLG2	9.37e-06	3	62	2	23403047
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	CASC3 SF3B1 TRA2B RBM33 ZC3H4 DHX57 TSNAX CKAP4 HNRNPLL	1.26e-05	807	62	9	22681889
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 CASC3 CACNB4 SF3B1 TRA2B ZC3H4 GOLGA8B GRIN2B GOLGA8A	5.02e-05	963	62	9	28671696
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	USP53 CASC3 ZNF532 EPB41L4B POLG BAD ARID5B EIF2AK4 TSNAX MBD5 F7	5.81e-05	1489	62	11	28611215
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	CASC3 TRA2B RBM33 ZC3H4 POLG DHX57 TACC2 CKAP4 FLG2 PLXNB2 VCPIP1	6.06e-05	1496	62	11	32877691
Pubmed	RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling.	CASC3 AXIN1	6.53e-05	7	62	2	21478859
Pubmed	Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.	SHANK1 GRIN2B	8.69e-05	8	62	2	19640847
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	CASC3 TRA2B RBM33 CKAP4 HRNR KHDC4	1.11e-04	425	62	6	24999758
Pubmed	Superresolution imaging of chemical synapses in the brain.	SHANK1 GRIN2B	1.12e-04	9	62	2	21144999
Pubmed	Characterization of the piRNA complex from rat testes.	RBM33 ZC3H4 GOLGA8B GOLGA8A	1.17e-04	140	62	4	16778019
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SF3B1 TRA2B ZNF532 ZC3H4 DHX57 CKAP4 HRNR FLG2 HNRNPLL	1.22e-04	1082	62	9	38697112
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	SHANK1 CACNB4 SF3B1 TRA2B TACC2 GRIN2B CKAP4 HNRNPLL VCPIP1	1.79e-04	1139	62	9	36417873
Pubmed	USP51 promotes deubiquitination and stabilization of ZEB1.	USP53 VCPIP1	2.41e-04	13	62	2	29119051
Pubmed	A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins.	SHANK1 GRIN2B	2.41e-04	13	62	2	15673434
Pubmed	Globozoospermia and lack of acrosome formation in GM130-deficient mice.	GOLGA8B GOLGA8A	2.41e-04	13	62	2	28055014
Pubmed	GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.	GOLGA8B GOLGA8A	2.41e-04	13	62	2	33740186
Pubmed	Loss of GM130 does not impair oocyte meiosis and embryo development in mice.	GOLGA8B GOLGA8A	2.41e-04	13	62	2	32873390
Pubmed	GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte.	GOLGA8B GOLGA8A	2.41e-04	13	62	2	21552007
Pubmed	GOLGA2 loss causes fibrosis with autophagy in the mouse lung and liver.	GOLGA8B GOLGA8A	2.41e-04	13	62	2	29128360
Pubmed	Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.	GOLGA8B GOLGA8A	2.41e-04	13	62	2	28028212
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SHANK1 SF3B1 ZNF532 RBM33 ARID5B RNF149 CKAP4 PLXNB2 AXIN1	2.68e-04	1203	62	9	29180619
Pubmed	GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.	GOLGA8B GOLGA8A	2.81e-04	14	62	2	30630895
Pubmed	Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation.	GOLGA8B GOLGA8A	2.81e-04	14	62	2	37831422
Pubmed	Golgb1 regulates protein glycosylation and is crucial for mammalian palate development.	GOLGA8B GOLGA8A	2.81e-04	14	62	2	27226319
Pubmed	Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.	SHANK1 GRIN2B	2.81e-04	14	62	2	21795692
Pubmed	Oligoasthenoteratospermia and sperm tail bending in PPP4C-deficient mice.	GOLGA8B GOLGA8A	2.81e-04	14	62	2	33543287
Pubmed	GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.	GOLGA8B GOLGA8A	3.23e-04	15	62	2	26165940
Pubmed	Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.	GOLGA8B GOLGA8A	3.23e-04	15	62	2	17204322
Pubmed	Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.	GOLGA8B GOLGA8A	3.23e-04	15	62	2	16413118
Pubmed	Golgi disruption and early embryonic lethality in mice lacking USO1.	GOLGA8B GOLGA8A	3.23e-04	15	62	2	23185636
Pubmed	The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells.	GOLGA8B GOLGA8A	3.23e-04	15	62	2	17046993
Pubmed	Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body.	GOLGA8B GOLGA8A	3.23e-04	15	62	2	17189423
Pubmed	RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis.	GOLGA8B GOLGA8A	3.23e-04	15	62	2	26083584
Pubmed	WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis.	GOLGA8B GOLGA8A	3.23e-04	15	62	2	37635409
Pubmed	Golga5 is dispensable for mouse embryonic development and postnatal survival.	GOLGA8B GOLGA8A	3.23e-04	15	62	2	28509431
Pubmed	LIM kinase 2 is widely expressed in all tissues.	GOLGA8B GOLGA8A	3.69e-04	16	62	2	16399995
Pubmed	Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport.	GOLGA8B GOLGA8A	3.69e-04	16	62	2	11784862
Pubmed	TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination.	HRNR FLG2	3.69e-04	16	62	2	31823782
Pubmed	p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis.	GOLGA8B GOLGA8A	3.69e-04	16	62	2	21640725
Pubmed	Molecular characterization of mitocalcin, a novel mitochondrial Ca2+-binding protein with EF-hand and coiled-coil domains.	GOLGA8B GOLGA8A	3.69e-04	16	62	2	16336229
Pubmed	SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.	GOLGA8B GOLGA8A	3.69e-04	16	62	2	18166528
Pubmed	Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis.	GOLGA8B GOLGA8A	4.18e-04	17	62	2	14718562
Pubmed	Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development.	GOLGA8B GOLGA8A	4.18e-04	17	62	2	28717168
Pubmed	The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.	GOLGA8B GOLGA8A	4.18e-04	17	62	2	27655914
Pubmed	Vesicle budding from endoplasmic reticulum is involved in calsequestrin routing to sarcoplasmic reticulum of skeletal muscles.	GOLGA8B GOLGA8A	4.18e-04	17	62	2	14728599
Pubmed	A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly.	GOLGA8B GOLGA8A	4.18e-04	17	62	2	20004763
Pubmed	Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.	GOLGA8B GOLGA8A	4.70e-04	18	62	2	21147753
Pubmed	N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration.	GOLGA8B GOLGA8A	4.70e-04	18	62	2	24227724
Pubmed	Flightless, secreted through a late endosome/lysosome pathway, binds LPS and dampens cytokine secretion.	GOLGA8B GOLGA8A	4.70e-04	18	62	2	22718342
Pubmed	Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2.	GOLGA8B GOLGA8A	4.70e-04	18	62	2	20943658
Pubmed	p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation.	GOLGA8B GOLGA8A	4.70e-04	18	62	2	15800058
Pubmed	Altered GLUT4 trafficking in adipocytes in the absence of the GTPase Arfrp1.	GOLGA8B GOLGA8A	4.70e-04	18	62	2	20230794
Pubmed	Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons.	GOLGA8B GOLGA8A	4.70e-04	18	62	2	24367100
Pubmed	Yip1B isoform is localized at ER-Golgi intermediate and cis-Golgi compartments and is not required for maintenance of the Golgi structure in skeletal muscle.	GOLGA8B GOLGA8A	4.70e-04	18	62	2	25208654
Pubmed	SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	23444373
Pubmed	Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	12646573
Pubmed	CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	35705037
Pubmed	Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	17664336
Pubmed	Spatial regulation of Raf kinase signaling by RKTG.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	17724343
Pubmed	Cell influx and contractile actomyosin force drive mammary bud growth and invagination.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	34042944
Pubmed	Stage-dependent function of Wnt5a during male external genitalia development.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	34255394
Pubmed	Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	15452145
Pubmed	Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1.	HOXA5 SF3B1	5.24e-04	19	62	2	15741318
Pubmed	Scrg1, a novel protein of the CNS is targeted to the large dense-core vesicles in neuronal cells.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	14622145
Pubmed	Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	38048369
Pubmed	Pilt is a coiled-coil domain-containing protein that localizes at the trans-Golgi complex and regulates its structure.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	22841714
Pubmed	Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2.	GOLGA8B GOLGA8A	5.24e-04	19	62	2	17003038
Pubmed	Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.	GOLGA8B GOLGA8A	5.82e-04	20	62	2	23918928
Pubmed	The COPI vesicle complex binds and moves with survival motor neuron within axons.	GOLGA8B GOLGA8A	5.82e-04	20	62	2	21300694
Pubmed	Intraflagellar transport molecules in ciliary and nonciliary cells of the retina.	GOLGA8B GOLGA8A	5.82e-04	20	62	2	20368623
Pubmed	Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity.	GOLGA8B GOLGA8A	5.82e-04	20	62	2	31949138
Pubmed	Development of the post-natal growth plate requires intraflagellar transport proteins.	GOLGA8B GOLGA8A	5.82e-04	20	62	2	17359961
Pubmed	The molecular complex of ciliary and golgin protein is crucial for skull development.	GOLGA8B GOLGA8A	5.82e-04	20	62	2	34128978
Pubmed	TMED2/emp24 is required in both the chorion and the allantois for placental labyrinth layer development.	GOLGA8B GOLGA8A	5.82e-04	20	62	2	30236446
Pubmed	Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron Viability.	GOLGA8B GOLGA8A	5.82e-04	20	62	2	29437892
Pubmed	A functional reference map of the RNF8 interactome in cancer.	SF3B1 CKAP4 HRNR FLG2	6.30e-04	218	62	4	35831895
Pubmed	Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development.	GOLGA8B GOLGA8A	6.42e-04	21	62	2	27118846
Pubmed	DJ-1 associates with synaptic membranes.	GOLGA8B GOLGA8A	6.42e-04	21	62	2	21645620
Pubmed	Single Cell Sequencing Reveals Mechanisms of Persistent Truncus Arteriosus Formation after PDGFRα and PDGFRβ Double Knockout in Cardiac Neural Crest Cells.	GOLGA8B GOLGA8A	6.42e-04	21	62	2	36292593
Pubmed	Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients.	HRNR FLG2	6.42e-04	21	62	2	19601998
Pubmed	Rap2 function requires palmitoylation and recycling endosome localization.	GOLGA8B GOLGA8A	6.42e-04	21	62	2	19061864
Pubmed	Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.	GOLGA8B GOLGA8A	6.42e-04	21	62	2	15229288
Pubmed	Ror2 enhances polarity and directional migration of primordial germ cells.	GOLGA8B GOLGA8A	6.42e-04	21	62	2	22216013
Pubmed	Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1.	GOLGA8B GOLGA8A	6.42e-04	21	62	2	20003423
Pubmed	Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa.	GOLGA8B GOLGA8A	6.42e-04	21	62	2	23386608
Pubmed	GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.	DHX57 CKAP4 HRNR FLG2	6.86e-04	223	62	4	33731348
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CASC3 TKFC SF3B1 INO80C GOLGA8B DHX57 EIF2AK4 CKAP4 FLG2	6.92e-04	1371	62	9	36244648
Pubmed	Control of craniofacial development by the collagen receptor, discoidin domain receptor 2.	GOLGA8B GOLGA8A	7.06e-04	22	62	2	36656123
Pubmed	Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body.	GOLGA8B GOLGA8A	7.06e-04	22	62	2	34897463
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.27e-16	149	62	11	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F	2.47e-07	99	62	5	17q12
Cytoband	2p22.1	DHX57 HNRNPLL	2.13e-04	16	62	2	2p22.1
Cytoband	10q26	MGMT TACC2	4.46e-04	23	62	2	10q26
Cytoband	Ensembl 112 genes in cytogenetic band chr2q23	CACNB4 MBD5	2.37e-03	53	62	2	chr2q23
Cytoband	Ensembl 112 genes in cytogenetic band chr15q14	GOLGA8B GOLGA8A	3.12e-03	61	62	2	chr15q14
GeneFamily	EF-hand domain containing\|S100 fused type protein family	HRNR FLG2	6.34e-05	7	32	2	1350
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D MICB GOLGA8B TBC1D3G GOLGA8A TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.55e-12	242	59	12	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.09e-12	90	59	9	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D MICB TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.42e-10	213	59	10	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D MICB TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.42e-10	213	59	10	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	ZNF703 TBC1D3 TBC1D3H TBC1D3L TBC1D3D GOLGA8B TACC2 ARHGEF17 PLXNB2 TBC1D3G GOLGA8A KHDC4 TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.33e-08	1075	59	16	PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	7.72e-08	281	59	9	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	7.72e-08	281	59	9	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.32e-07	320	59	9	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	ZNF703 TBC1D3 TBC1D3H TBC1D3L TBC1D3D BAD GOLGA8B CKAP4 ARHGEF17 PLXNB2 TBC1D3G GOLGA8A KHDC4 TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.88e-07	1466	59	17	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	USP53 TBC1D3 TBC1D3H TBC1D3L MGMT TBC1D3D BAD GOLGA8B ARHGEF17 TBC1D3G GOLGA8A TBC1D3C TBC1D3B TBC1D3K TBC1D3F	4.01e-07	1153	59	15	PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05	ZNF703 TBC1D3 TBC1D3H TBC1D3L TBC1D3D GOLGA8B TBC1D3G GOLGA8A TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.58e-05	1049	59	12	PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
ToppCell	IPF-Lymphoid-T_Regulatory\|World / Disease state, Lineage and Cell class	ARID5B GOLGA8B TNFRSF18 GOLGA8A HNRNPLL	5.96e-06	185	62	5	77fbecdab10bacc005b1c7e22ca414cfecef13c1
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ARID5B GOLGA8B GOLGA8A HNRNPLL HERC5	7.89e-06	196	62	5	4a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SF3B1 TRA2B RBM33 GOLGA8A HERC5	8.70e-06	200	62	5	12f1685ce8f218433068e090c9d839cd5a1910bf
Disease	sleep efficiency	GOLGA8B GOLGA8A	3.15e-05	5	53	2	EFO_0803364
Disease	progeria (implicated_via_orthology)	POLG VCPIP1	8.80e-05	8	53	2	DOID:3911 (implicated_via_orthology)
Disease	myelodysplastic syndrome (implicated_via_orthology)	SF3B1 POLG	3.27e-04	15	53	2	DOID:0050908 (implicated_via_orthology)
Disease	response to haloperidol	ARID5B EIF2AK4	3.74e-04	16	53	2	GO_1905119
Disease	sucrose liking measurement	GOLGA8B GOLGA8A	5.89e-04	20	53	2	EFO_0010157
Disease	CCL4 measurement	TBC1D3 TBC1D3F	5.89e-04	20	53	2	EFO_0004751
Disease	diabetes mellitus (implicated_via_orthology)	PTPRN F7	1.00e-03	26	53	2	DOID:9351 (implicated_via_orthology)
Disease	macular degeneration (is_marker_for)	TRA2B BAD	1.00e-03	26	53	2	DOID:4448 (is_marker_for)
Disease	Epilepsy	CACNB4 POLG GRIN2B	1.00e-03	109	53	3	C0014544
Disease	macrophage inflammatory protein 1b measurement	TBC1D3 TBC1D3B TBC1D3F	1.90e-03	136	53	3	EFO_0008219
Disease	refractive error	COL4A4 GOLGA8B GRIN2B GOLGA8A	2.80e-03	326	53	4	MONDO_0004892

Protein segments in the cluster

Peptide	Gene	Start	Entry
GGHGAASPSEKGAHP	CKAP4	11	Q07065
KSDSHGPKEDGGFRH	CKAP4	381	Q07065
LHGGSPDFVGNGKHR	EIF2AK4	226	Q9P2K8
PAGDGPSGSGKHHRQ	BAD	26	Q92934
GQPGSHGRDGHAGEK	COL4A4	581	P53420
KPHRNRGSPGGYSHD	CACNB4	501	O00305
GAAHHQSFGKQKSGP	ADAT1	211	Q9BUB4
TVTHRTNSGGGDGPH	RBM33	966	Q96EV2
GGRSFSQPEAGGSHH	HNRNPLL	56	Q8WVV9
GSAKDAAPGGGHHQA	GOLGA8F;	296	Q08AF8
SPTGLGQGHTGHVRF	ARHGEF17	1961	Q96PE2
QHESGSGKSSGFGQH	FLG2	976	Q5D862
HGSGTGKSSGFAQHE	FLG2	1131	Q5D862
RTASKGIFGDHPGHS	PTPRN	246	Q16849
HEGHRLGKPGLGGSS	MGMT	171	P16455
AGPGPKQGHHSSSDS	IMUP	41	Q9GZP8
LQDGSAQHHPKGGST	HPS4	276	Q9NQG7
HGDIQCGGHAPGSSK	PLXNB2	346	O15031
EKGHHLGRSSPFGKS	LRRC36	711	Q1X8D7
VAPSPGSDSHHGGKN	HOXA5	106	P20719
RHGSGSGQSSGFGHK	HRNR	921	Q86YZ3
ARGGPKDTQPSYHHG	POLG	721	P54098
HSGNHGTHPVPSGKA	MICB	286	Q29980
TFGAGKHGQLGHNST	HERC5	266	Q9UII4
PNFVHSGHGGAVAGK	INO80C	86	Q6PI98
GSAKDAAPGGGHHQA	GOLGA8DP	296	Q0D2H9
GGHSPDDHRVRGSGK	BCLAF3	136	A2AJT9
AGGQHGGRSGETVKH	CASC3	331	O15234
RGGRGGRSHASKSHG	DHX57	21	Q6P158
LGGAASGHGKHVPKS	AXIN1	506	O15169
SEHGQKSPFRGSHGG	MBD5	206	Q9P267
EEHGGHKNASSFPQG	KHDC4	576	Q7Z7F0
HPGADHGEGRSSTNG	KNCN	81	A6PVL3
GDSAKDASPGGGHHQ	GOLGA8B	461	A8MQT2
NGGTPFLTAASGRHH	EPB41L4B	491	Q9H329
SAKDASPGGGHHQAG	GOLGA8A	491	A7E2F4
GNSSGRKHRGHSESP	SNX29P2	206	Q8IUI4
KGDSGGPHATHYRGT	F7	401	P08709
GSFHRGAGKPSVHSQ	ODAD3	56	A5D8V7
DTHGRSEAFPTGHKG	SPATA31E1	941	Q6ZUB1
SERHSLQGFHSPNGG	TBC1D3L	216	B9A6J9
GGDSHHGGASYVPER	SHANK1	1901	Q9Y566
HSGGGSEGHKLPLSS	ARID5B	1061	Q14865
SNRSHSHTGVGKGPA	USP53	416	Q70EK8
SERHSLQGFHSPNGG	TBC1D3B	216	A6NDS4
SERHSLQGFHSPNGG	TBC1D3H	216	P0C7X1
SGRFGDSSPKEGAHG	RNF149	61	Q8NC42
GGEKDGHNPTGNGLH	ZNF532	76	Q9HCE3
SRGGSPHHSDCKNGG	ZNF703	221	Q9H7S9
SERHSLQGFHSPNGG	TBC1D3F	216	A6NER0
HATPGHGGATSSARK	SF3B1	276	O75533
APGTRRHFSTSGGGH	nan	16	A6NN06
HSAQPPRKGGAGHTD	TACC2	631	O95359
SERHSLQGFHSPNGG	TBC1D3E	216	A0A087X179
QGKGHSLGTASGNPH	VCPIP1	1026	Q96JH7
GGGGSYRSRDHDKPH	ZC3H4	371	Q9UPT8
ASGTFSGGHEGHCKP	TNFRSF18	116	Q9Y5U5
GSGGFRKRKHDNFPH	TSNAX	6	Q99598
SERHSLQGFHSPNGG	TBC1D3D	216	A0A087WVF3
GSGHEPAHAGFIGKG	TKFC	56	Q3LXA3
SERHSLQGFHSPNGG	TBC1D3G	216	Q6DHY5
SERHSLQGFHSPNGG	TBC1D3	216	Q8IZP1
GSAHGSGKSARHTPA	TRA2B	21	P62995
SERHSLQGFHSPNGG	TBC1D3K	216	A0A087X1G2
SERHSLQGFHSPNGG	TBC1D3I	216	A0A087WXS9
SERHSLQGFHSPNGG	TBC1D3C	216	Q6IPX1
HGTGDKHGVVSGVPA	GRIN2B	1181	Q13224