Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	aa-tRNA-synth_II	EIF2AK4 DARS2	2.04e-03	18	70	2	IPR006195
Domain	AA_TRNA_LIGASE_II	EIF2AK4 DARS2	2.04e-03	18	70	2	PS50862
Domain	-	SPTBN4 PTPN14 SH2B3 ELMO2 OSBPL10 AKAP13	3.44e-03	391	70	6	2.30.29.30
Domain	PH	SPTBN4 SH2B3 ELMO2 OSBPL10 AKAP13	3.88e-03	278	70	5	SM00233
Domain	PH_DOMAIN	SPTBN4 SH2B3 ELMO2 OSBPL10 AKAP13	3.94e-03	279	70	5	PS50003
Domain	PH_domain	SPTBN4 SH2B3 ELMO2 OSBPL10 AKAP13	4.00e-03	280	70	5	IPR001849
Domain	Bromodomain_CS	BPTF BRWD1	4.25e-03	26	70	2	IPR018359
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	BPTF RRS1 CAPN1 NUP98 HELZ2 SMC4 SRPK1 LAS1L HECTD1 SNRNP200	9.57e-07	653	72	10	22586326
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	SMC4 SRPK1 AKAP13 EIF2AK4 HECTD1 SNRNP200	4.05e-06	202	72	6	33005030
Pubmed	TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes.	PRF1 TNFRSF1A	4.23e-06	2	72	2	10201999
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 KMT2D MINK1 ASPM SRPK1 SNRNP200	9.38e-06	234	72	6	36243803
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	DNHD1 WDR33 CAPN1 NUP98 ASPM SRPK1 TSEN54 LAS1L SNRNP200	1.00e-05	670	72	9	22990118
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PTPN14 MAP7D3 ELMO2 DAPK2 MINK1 OSBPL10 AKAP13 N4BP3 HECTD1 OTOG	1.10e-05	861	72	10	36931259
Pubmed	NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation.	BPTF NUP98	1.27e-05	3	72	2	38940430
Pubmed	Neuron-related blood inflammatory markers as an objective evaluation tool for major depressive disorder: An exploratory pilot case-control study.	IL34 TNFRSF1A	1.27e-05	3	72	2	30059939
Pubmed	Cutting edge: systemic inhibition of angiogenesis underlies resistance to tumors during acute toxoplasmosis.	PRF1 TNFRSF1A	1.27e-05	3	72	2	11342601
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	PTPN14 SRPK1 AKAP13 N4BP3 HECTD1 SNRNP200	1.53e-05	255	72	6	15324660
Pubmed	Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection.	PRF1 TNFRSF1A	2.53e-05	4	72	2	11752172
Pubmed	Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo.	PRF1 TNFRSF1A	2.53e-05	4	72	2	19050279
Pubmed	Acute hepatotoxicity of Pseudomonas aeruginosa exotoxin A in mice depends on T cells and TNF.	PRF1 TNFRSF1A	4.21e-05	5	72	2	9820556
Pubmed	Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules.	PRF1 TNFRSF1A	4.21e-05	5	72	2	10946317
Pubmed	The role of TNF-TNFR2 interactions in generation of CTL responses and clearance of hepatic adenovirus infection.	PRF1 TNFRSF1A	4.21e-05	5	72	2	12960267
Pubmed	Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells.	PRF1 TNFRSF1A	6.31e-05	6	72	2	27403737
Pubmed	Cytotoxic mechanisms employed by mouse T cells to destroy pancreatic β-cells.	PRF1 TNFRSF1A	6.31e-05	6	72	2	22773667
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	BPTF MRPL20 TOMM70 KMT2D MAP7D3 NUP98 SMC4 SNRNP200 DARS2	6.82e-05	857	72	9	25609649
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	BPTF KMT2D WDR33 SMC4 LAS1L DARS2	7.71e-05	341	72	6	32971831
Pubmed	iNKT cell production of GM-CSF controls Mycobacterium tuberculosis.	PRF1 TNFRSF1A	8.82e-05	7	72	2	24391492
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	RRS1 ASPM SRPK1 LAS1L HECTD1 DARS2	1.10e-04	364	72	6	24778252
Pubmed	Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation.	BPTF KMT2D	1.17e-04	8	72	2	21447625
Pubmed	Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions.	PRF1 TNFRSF1A	1.17e-04	8	72	2	11046015
Pubmed	Enhanced suppression of polyclonal CD8+25+ regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes.	PRF1 HLA-H	1.17e-04	8	72	2	28096300
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	BPTF KMT2D PTPN14 MAP7D3 WDR33 SMC4 SNRNP200	1.43e-04	549	72	7	38280479
Pubmed	Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice.	PRF1 HLA-H	1.51e-04	9	72	2	23230000
Pubmed	B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin).	PRF1 TNFRSF1A	1.51e-04	9	72	2	22212899
Pubmed	Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice.	PRF1 TNFRSF1A	1.51e-04	9	72	2	10072530
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	BPTF MAP7D3 RRS1 ASPM SRPK1 LAS1L HECTD1 SNRNP200	1.73e-04	759	72	8	35915203
Pubmed	Localization of serine kinases, SRPK1 (SFRSK1) and SRPK2 (SFRSK2), specific for the SR family of splicing factors in mouse and human chromosomes.	SRPK1 PJA1	1.88e-04	10	72	2	10198174
Pubmed	CD8+ T cells induce cachexia during chronic viral infection.	PRF1 TNFRSF1A	1.88e-04	10	72	2	31110314
Pubmed	Association of beta2-microglobulin with the alpha3 domain of H-2Db heavy chain.	HLA-H TAP2	1.88e-04	10	72	2	14735325
Pubmed	Hectd1 is required for development of the junctional zone of the placenta.	PRF1 HECTD1	1.88e-04	10	72	2	24855001
Pubmed	Regulation of major histocompatibility complex and TAP gene products in preimplantation mouse stage embryos.	HLA-H TAP2	1.88e-04	10	72	2	9764360
Pubmed	CD8+ T cells targeting a single immunodominant epitope are sufficient for elimination of established SV40 T antigen-induced brain tumors.	PRF1 HLA-H	1.88e-04	10	72	2	18768900
Pubmed	Immune effectors required for hepatitis B virus clearance.	PRF1 TNFRSF1A	1.88e-04	10	72	2	20080755
Pubmed	Graft-versus-leukemia (GVL) against mouse blast-crisis chronic myelogenous leukemia (BC-CML) and chronic-phase chronic myelogenous leukemia (CP-CML): shared mechanisms of T cell killing, but programmed death ligands render CP-CML and not BC-CML GVL resistant.	PRF1 TNFRSF1A	1.88e-04	10	72	2	21768400
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	MAP7D3 NUP98 ASPM SMC4 SNRNP200	1.94e-04	256	72	5	33397691
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PTPN14 MAP7D3 RRS1 CAPN1 NUP98 HELZ2 SMC4 SRPK1 LAS1L SNRNP200	2.57e-04	1257	72	10	36526897
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	MRPL20 WDR33 RRS1 HELZ2 SRPK1 LAS1L SNRNP200 DUSP11	2.62e-04	807	72	8	22681889
Pubmed	Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential.	PRF1 TNFRSF1A	2.75e-04	12	72	2	29436413
Pubmed	Ham-2 corrects the class I antigen-processing defect in RMA-S cells.	HLA-H TAP2	2.75e-04	12	72	2	1538753
Pubmed	Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus.	PRF1 HLA-H	2.75e-04	12	72	2	25902529
Pubmed	Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.	SIRT4 DARS2	3.25e-04	13	72	2	19209188
Pubmed	Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway.	PRF1 HLA-H	3.25e-04	13	72	2	17509909
Pubmed	Interaction of murine MHC class I molecules with tapasin and TAP enhances peptide loading and involves the heavy chain alpha3 domain.	HLA-H TAP2	3.25e-04	13	72	2	9973410
Pubmed	MUC1-specific anti-tumor responses: molecular requirements for CD4-mediated responses.	PRF1 TNFRSF1A	3.78e-04	14	72	2	12147624
Pubmed	Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.	SMC4 HECTD1	3.78e-04	14	72	2	26166704
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TOMM70 ELMO2 MINK1 OSBPL10 SRPK1 AKAP13 EIF2AK4	3.97e-04	650	72	7	38777146
Pubmed	MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis.	PRF1 HLA-H	4.36e-04	15	72	2	21964024
Pubmed	Control of Viral Infection by Natural Killer Cell Inhibitory Receptors.	PRF1 HLA-H	4.98e-04	16	72	2	32726632
Pubmed	Cellular and molecular requirements for rejection of B16 melanoma in the setting of regulatory T cell depletion and homeostatic proliferation.	PRF1 HLA-H	6.33e-04	18	72	2	22312128
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	RRS1 NUP98 HELZ2 SRPK1 LAS1L	6.38e-04	332	72	5	25693804
Pubmed	A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.	PRF1 TNFRSF1A	7.06e-04	19	72	2	34249474
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PHEX SPTBN4 BPTF ANTXR2 WDR33 RRS1 NUP98 ASPM SMC4 EIF2AK4	7.52e-04	1442	72	10	35575683
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	BPTF RRS1 CAPN1 SRPK1 LAS1L SNRNP200	8.37e-04	533	72	6	30554943
Pubmed	Myosin-X recruits lamellipodin to filopodia tips.	SPRYD3 OSBPL10 PJA1	8.50e-04	89	72	3	36861887
Pubmed	The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons.	DONSON LHX6	8.65e-04	21	72	2	33739968
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MRPL20 PTPN14 RRS1 MINK1 ASPM SRPK1 AKAP13 LAS1L SNRNP200 DARS2	9.50e-04	1487	72	10	33957083
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	TOMM70 MAP7D3 RRS1 SMC4 SRPK1 HECTD1	9.56e-04	547	72	6	37267103
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	NUP98 ASPM SMC4 SNRNP200	9.64e-04	210	72	4	16565220
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MRPL20 TOMM70 PTPN14 MAP7D3 WDR33 RRS1 NUP98 MIGA1 LAS1L DARS2	9.95e-04	1496	72	10	32877691
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BPTF KMT2D MINK1 NUP98 HELZ2 IQCN SNRNP200	1.11e-03	774	72	7	15302935
Pubmed	Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor.	PRF1 TNFRSF1A	1.13e-03	24	72	2	34526512
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	PTPN14 WDR33 SRPK1 SNRNP200	1.14e-03	220	72	4	24550385
Pubmed	Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.	FADS3 ANTXR2 HLA-H TNFRSF1A	1.24e-03	225	72	4	23341629
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	PTPN14 MINK1 SMC4 SRPK1 BRWD1	1.44e-03	399	72	5	37536630
Pubmed	Nucleolar proteome dynamics.	RRS1 SRPK1 LAS1L SNRNP200 DUSP11	1.79e-03	419	72	5	15635413
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PTPN14 RRS1 CAPN1 ASPM SMC4 SRPK1 AKAP13 LAS1L SNRNP200	1.87e-03	1353	72	9	29467282
Pubmed	Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.	CAPN1 SRPK1	1.89e-03	31	72	2	16140986
Pubmed	A protein interaction landscape of breast cancer.	TOMM70 PTPN14 RRS1 SRPK1 LAS1L TAP2	2.02e-03	634	72	6	34591612
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	BPTF KMT2D ANTXR2 MAP7D3 WWC3 SH2B3 ELMO2 PRF1 NUP98 HLA-H AKAP13 TSEN54 TAP2 SNRNP200 BTN3A1 BRWD1	2.23e-06	1492	72	16	M40023
Coexpression	GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP	TBXA2R RSAD2 PTPN14 DONSON PRF1 DAPK2 HELZ2 HLA-H TAP2 SIRT4	6.91e-06	616	72	10	MM977
Coexpression	GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP	RSAD2 WWC3 HELZ2 OSBPL10 TAP2 BTN3A1	1.73e-05	197	72	6	M7545
Coexpression	ZENG_GU_POST_ICB_METAGENE_31	DONSON SH2B3 PRF1 HLA-H TNFRSF1A ERMARD	2.41e-05	209	72	6	MM17088
Coexpression	GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP	TBXA2R RSAD2 PTPN14 DONSON PRF1 DAPK2 HELZ2 TAP2 SIRT4	2.47e-05	567	72	9	M1097
Coexpression	SAGIV_CD24_TARGETS_UP	ASPM SMC4 N4BP3	2.95e-05	22	72	3	M4144
Coexpression	FOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_DN	IL34 RSAD2 PTPN14 ZMYND10 CAPN1 HELZ2 LAS1L SYNE4 BTN3A1 FCHSD1	3.58e-05	746	72	10	M40863
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN14 FADS3 MARCHF3 ASPM PABPC4L	1.44e-06	119	72	5	c3f1223356e7f245a460ea5568a223e34e458dc1
Disease	aspirin-induced respiratory disease (is_implicated_in)	TBXA2R TAP2	2.92e-04	11	69	2	DOID:0080822 (is_implicated_in)
Disease	birth weight	PTPN14 SH2B3 PABPC4L AKAP13 MIGA1 PJA1	3.44e-04	399	69	6	EFO_0004344
Disease	colon carcinoma (is_marker_for)	KMT2D TNFRSF1A	4.13e-04	13	69	2	DOID:1520 (is_marker_for)
Disease	multiple sclerosis (is_implicated_in)	PRF1 TNFRSF1A TAP2	6.77e-04	73	69	3	DOID:2377 (is_implicated_in)
Disease	ankylosing spondylitis	ANTXR2 SH2B3 TNFRSF1A	1.28e-03	91	69	3	EFO_0003898
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	SH2B3 CFAP97D1 HELZ2 TSEN54	1.84e-03	222	69	4	EFO_0008317, EFO_0020943

Protein segments in the cluster

Peptide	Gene	Start	Entry
LFQVIRLYQRRRWTI	CYP4Z2P	26	Q8N1L4
QDTTLRYWERRRSVQ	C9orf50	281	Q5SZB4
QGLYRDTVRLWRLFR	EIF2AK4	816	Q9P2K8
ELRWRSIQYASRGER	BTN3A1	311	O00481
RNRTERLSDLLDWRY	GYS2	586	P54840
QAQYLEEKRRREREW	AKAP13	2591	Q12802
WALLRRQYDRVSLMR	ANTXR2	456	P58335
AQETIRRLQRYWEAR	DNHD1	1151	Q96M86
WLRQLSRRGQLLVRY	DNHD1	4551	Q96M86
RDPELRDWRRNYLLN	ANO9	516	A1A5B4
NILWNRIRNYLSIFR	CAPN1	611	P07384
SRRKYWFLNRRLIIE	BPTF	466	Q12830
IQSYWRMRQDRVRFL	ASPM	1566	Q8IZT6
RADRDRYIRVNWNEI	ASTL	196	Q6HA08
IIWRQRLSRDGRYLV	NWD2	1566	Q9ULI1
IQATWRGYRVRRNLA	IQCN	956	Q9H0B3
WEAARRAEQRRVYLE	HLA-H	171	P01893
YIQILERRRAFSRWL	NUP98	1296	P52948
WYRRSIARRLFLGDQ	KIAA1109	4271	Q2LD37
WISQQRLSLYRRSER	KCNT1	1106	Q5JUK3
RRALSQYLTDRARWR	PRF1	361	P14222
QRYALNRITVWRSRS	LAS1L	66	Q9Y4W2
RQIYASDWVRRARGN	LHX6	136	Q9UPM6
DREFGQWVRLLYRLR	GARIN5A	221	Q6IPT2
RSRKLYGQRERVWAL	FCHSD1	146	Q86WN1
GRRRTWDDDYVLKRQ	HECTD1	1756	Q9ULT8
QRAQVSERELRYLWV	IL34	81	Q6ZMJ4
KPNASRAAQDRRRWY	DUSP11	346	O75319
RRRQERFWYCRLALN	ELMO2	561	Q96JJ3
VNLENFRKQYVRRRW	DAPK2	301	Q9UIK4
YDRRASEIDWQNSRR	CFAP97D1	136	B2RV13
NRFYRRLSALVWEVR	BRWD1	1216	Q9NSI6
YNEWRRTNQRVILLI	MARCHF3	211	Q86UD3
ERRRLADDYQQKRWS	MAP7D3	151	Q8IWC1
SLRNVVLRDYIYNWR	DONSON	551	Q9NYP3
LAWRLYDRQFRPSQR	KLB	721	Q86Z14
WVERTLRSRQRQNYL	ERMARD	561	Q5T6L9
LRLLWRRRVYSAQGS	HELZ2	1791	Q9BYK8
IERRVYDISRWAQRH	FADS3	41	Q9Y5Q0
IRLMWSQRDAYLRRS	PABPC4L	81	P0CB38
REGLRLYLQVDQRWV	OTOG	631	Q6ZRI0
RPRSNSAWQIYLQRR	MINK1	696	Q8N4C8
LRRWEQALTFRNRQA	MIGA1	221	Q8NAN2
WIQYRRQNTFLVLRD	DARS2	71	Q6PI48
QLWDRIDYRAIVSRR	SPDYA	166	Q5MJ70
AQLWLRNRVTDRYFR	MRPL20	6	Q9BYC9
SSWREYKELLQRRQV	TSEN54	376	Q7Z6J9
YRELHNAWSVRQERR	RNF151	161	Q2KHN1
VENLQKLRRWCRDYR	RSAD2	201	Q8WXG1
YRDSIFRRLWQLQAQ	SYNE4	186	Q8N205
VRNRIGRQAVIYRWN	PTPN14	241	Q15678
VRSAPIRQRYWARNF	SIRT4	96	Q9Y6E7
LLMRRSAYRIRDQIW	SLC9A5	511	Q14940
QCRQLYWRRDLERAL	TAP2	361	Q03519
QYIRRLAAEATEWQR	SRPK1	226	Q96SB4
MESRNLWREVTRYLR	OSBPL10	696	Q9BXB5
DDLNLHYRFLNWRRR	SPRYD3	16	Q8NCJ5
RRRWGYQRARDDTKE	RRS1	141	Q15050
REAFRAYRKWINDRR	PHEX	651	P78562
RVAYQKDRRWRVVTL	SMC4	726	Q9NTJ3
AAARELARQYWLFAR	SH2B3	36	Q9UQQ2
ALRRQWLRDALAVYR	SPTBN4	871	Q9H254
IYLWSRQQRRREARG	TOMM70	56	O94826
RDIDAFWLQRQLSRF	SNRNP200	261	O75643
WRQLDLAQRTLYREV	ZNF550	26	Q7Z398
QDLRLQARRWAETYR	ZMYND10	366	O75800
QARRWAETYRLDVLE	ZMYND10	371	O75800
WVYILFRRAVLRRLQ	TBXA2R	306	P21731
YLENRIWQRDQRDMR	WDR33	66	Q9C0J8
WIAALRRKYRSREQT	PJA1	371	Q8NG27
LREAQYSMLATWRRR	TNFRSF1A	396	P19438
TRLVDRVRLNWQYEE	WWC3	226	Q9ULE0
RVRLNWQYEEARKRV	WWC3	231	Q9ULE0
RYVQRLQWLLSGSRR	VWA3A	936	A6NCI4
EATRIYWSLRTNNRR	KMT2D	5211	O14686
RTWQEEKERVLRYQR	N4BP3	491	O15049