Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	lysine-acetylated histone binding	BRD3 BRD2	1.12e-03	30	33	2	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD3 BRD2	1.20e-03	31	33	2	GO:0140033
GeneOntologyMolecularFunction	carbohydrate binding	SFTPA1 CLEC4M SFTPA2 ADGRL2	1.63e-03	310	33	4	GO:0030246
GeneOntologyMolecularFunction	dynein intermediate chain binding	DYNLT2B DYNC2H1	1.70e-03	37	33	2	GO:0045505
Domain	BET	BRD3 BRD2	1.70e-05	4	32	2	PF17035
Domain	NET_dom	BRD3 BRD2	1.70e-05	4	32	2	IPR027353
Domain	NET	BRD3 BRD2	1.70e-05	4	32	2	PS51525
Domain	C-type_lectin_CS	SFTPA1 CLEC4M SFTPA2	5.38e-05	43	32	3	IPR018378
Domain	C_TYPE_LECTIN_1	SFTPA1 CLEC4M SFTPA2	3.43e-04	80	32	3	PS00615
Domain	Lectin_C	SFTPA1 CLEC4M SFTPA2	3.96e-04	84	32	3	PF00059
Domain	CLECT	SFTPA1 CLEC4M SFTPA2	3.96e-04	84	32	3	SM00034
Domain	C_TYPE_LECTIN_2	SFTPA1 CLEC4M SFTPA2	4.10e-04	85	32	3	PS50041
Domain	C-type_lectin-like	SFTPA1 CLEC4M SFTPA2	4.25e-04	86	32	3	IPR001304
Domain	-	SFTPA1 CLEC4M SFTPA2	6.04e-04	97	32	3	3.10.100.10
Domain	C-type_lectin-like/link	SFTPA1 CLEC4M SFTPA2	6.41e-04	99	32	3	IPR016186
Domain	CTDL_fold	SFTPA1 CLEC4M SFTPA2	8.03e-04	107	32	3	IPR016187
Domain	HormR	ADGRL2 GLP1R	8.32e-04	25	32	2	SM00008
Domain	Bromodomain_CS	BRD3 BRD2	9.01e-04	26	32	2	IPR018359
Domain	HRM	ADGRL2 GLP1R	1.05e-03	28	32	2	PF02793
Domain	GPCR_2_secretin-like_CS	ADGRL2 GLP1R	1.54e-03	34	32	2	IPR017983
Domain	BROMODOMAIN_1	BRD3 BRD2	1.82e-03	37	32	2	PS00633
Domain	Bromodomain	BRD3 BRD2	1.92e-03	38	32	2	PF00439
Domain	G_PROTEIN_RECEP_F2_1	ADGRL2 GLP1R	2.13e-03	40	32	2	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRL2 GLP1R	2.13e-03	40	32	2	PS50227
Domain	GPCR_2_extracellular_dom	ADGRL2 GLP1R	2.13e-03	40	32	2	IPR001879
Domain	BROMODOMAIN_2	BRD3 BRD2	2.24e-03	41	32	2	PS50014
Domain	BROMO	BRD3 BRD2	2.35e-03	42	32	2	SM00297
Domain	Bromodomain	BRD3 BRD2	2.35e-03	42	32	2	IPR001487
Domain	-	BRD3 BRD2	2.35e-03	42	32	2	1.20.920.10
Domain	G_PROTEIN_RECEP_F2_2	ADGRL2 GLP1R	3.31e-03	50	32	2	PS00650
Domain	7tm_2	ADGRL2 GLP1R	3.31e-03	50	32	2	PF00002
Domain	GPCR_2-like	ADGRL2 GLP1R	4.73e-03	60	32	2	IPR017981
Domain	GPCR_2_secretin-like	ADGRL2 GLP1R	4.73e-03	60	32	2	IPR000832
Domain	G_PROTEIN_RECEP_F2_4	ADGRL2 GLP1R	4.89e-03	61	32	2	PS50261
Domain	Collagen	SFTPA1 SFTPA2	9.29e-03	85	32	2	PF01391
Domain	Collagen	SFTPA1 SFTPA2	9.29e-03	85	32	2	IPR008160
Pathway	REACTOME_DEFECTIVE_CSF2RB_CAUSES_SMDP5	SFTPA1 SFTPA2	9.82e-05	8	27	2	M27575
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_SURFACTANT_METABOLISM	SFTPA1 SFTPA2	1.57e-04	10	27	2	M27573
Pathway	REACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS	SFTPA1 SFTPA2	3.17e-04	14	27	2	MM15011
Pathway	REACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS	SFTPA1 SFTPA2	4.17e-04	16	27	2	M925
Pathway	WP_BARDETBIEDL_SYNDROME	DYNLT2B DYNC2H1 CEP164	6.17e-04	88	27	3	M45557
Pathway	WP_COMPLEMENT_SYSTEM	SFTPA1 CLEC4M SFTPA2	7.95e-04	96	27	3	M39581
Pathway	REACTOME_REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND	SFTPA1 SFTPA2	7.97e-04	22	27	2	M27571
Pathway	REACTOME_REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND	SFTPA1 SFTPA2	7.97e-04	22	27	2	MM15284
Pathway	REACTOME_SURFACTANT_METABOLISM	SFTPA1 SFTPA2	8.72e-04	23	27	2	MM15279
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	ADGRL2 GLP1R	9.50e-04	24	27	2	MM15992
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	ADGRL2 GLP1R	9.50e-04	24	27	2	M39643
Pathway	WP_INTRAFLAGELLAR_TRANSPORT_PROTEINS_BINDING_TO_DYNEIN	DYNLT2B DYNC2H1	1.20e-03	27	27	2	M39827
Pathway	REACTOME_SURFACTANT_METABOLISM	SFTPA1 SFTPA2	1.49e-03	30	27	2	M27566
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	GNB3 GLP1R	1.69e-03	32	27	2	MM14983
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB3 GLP1R	1.80e-03	33	27	2	M10322
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB3 GLP1R	1.80e-03	33	27	2	MM15066
Pubmed	Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome.	SFTPA1 SFTPA2	9.28e-07	2	34	2	31354704
Pubmed	Signaling Pathways That Mediate Alveolar Macrophage Activation by Surfactant Protein A and IL-4.	SFTPA1 SFTPA2	9.28e-07	2	34	2	35444643
Pubmed	Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma.	SFTPA1 SFTPA2	9.28e-07	2	34	2	31350355
Pubmed	Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2.	SFTPA1 SFTPA2	9.28e-07	2	34	2	23069847
Pubmed	Ablation of SP-A has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences.	SFTPA1 SFTPA2	9.28e-07	2	34	2	19055785
Pubmed	Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo.	SFTPA1 SFTPA2	9.28e-07	2	34	2	10749762
Pubmed	Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.	SFTPA1 SFTPA2	9.28e-07	2	34	2	34484180
Pubmed	The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A.	SFTPA1 SFTPA2	9.28e-07	2	34	2	17593964
Pubmed	Surfactant protein A limits Pneumocystis murina infection in immunosuppressed C3H/HeN mice and modulates host response during infection.	SFTPA1 SFTPA2	9.28e-07	2	34	2	15857803
Pubmed	Surfactant protein-A reduces translocation of mediators from the lung into the circulation.	SFTPA1 SFTPA2	9.28e-07	2	34	2	20715984
Pubmed	Studies of the structure of lung surfactant protein SP-A.	SFTPA1 SFTPA2	9.28e-07	2	34	2	2610270
Pubmed	Surfactant protein-A binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	9922219
Pubmed	Maternal surfactant protein A influences the immunoprotective properties of milk in a murine model.	SFTPA1 SFTPA2	9.28e-07	2	34	2	24858142
Pubmed	Effects of surfactant protein-A on the interaction of Pneumocystis murina with its host at different stages of the infection in mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	19335775
Pubmed	The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription.	BRD3 BRD2	9.28e-07	2	34	2	18406326
Pubmed	Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus.	SFTPA1 SFTPA2	9.28e-07	2	34	2	11867335
Pubmed	Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin.	SFTPA1 SFTPA2	9.28e-07	2	34	2	12922979
Pubmed	Pneumocystis murina colonization in immunocompetent surfactant protein A deficient mice following environmental exposure.	SFTPA1 SFTPA2	9.28e-07	2	34	2	19228388
Pubmed	SP-A preserves airway homeostasis during Mycoplasma pneumoniae infection in mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	19494306
Pubmed	An 11-nt sequence polymorphism at the 3'UTR of human SFTPA1 and SFTPA2 gene variants differentially affect gene expression levels and miRNA regulation in cell culture.	SFTPA1 SFTPA2	9.28e-07	2	34	2	24793167
Pubmed	Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.	SFTPA1 SFTPA2	9.28e-07	2	34	2	24954098
Pubmed	Characterization of a second human pulmonary surfactant-associated protein SP-A gene.	SFTPA1 SFTPA2	9.28e-07	2	34	2	1372511
Pubmed	Lung effector memory and activated CD4+ T cells display enhanced proliferation in surfactant protein A-deficient mice during allergen-mediated inflammation.	SFTPA1 SFTPA2	9.28e-07	2	34	2	21257967
Pubmed	The Pseudomonas aeruginosa flagellum confers resistance to pulmonary surfactant protein-A by impacting the production of exoproteases through quorum-sensing.	SFTPA1 SFTPA2	9.28e-07	2	34	2	21205009
Pubmed	Surfactant protein A modulates neuroinflammation in adult mice upon pulmonary infection.	SFTPA1 SFTPA2	9.28e-07	2	34	2	38964703
Pubmed	Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms.	SFTPA1 SFTPA2	9.28e-07	2	34	2	18159253
Pubmed	Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.	SFTPA1 SFTPA2	9.28e-07	2	34	2	34917085
Pubmed	Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation.	SFTPA1 SFTPA2	9.28e-07	2	34	2	22219327
Pubmed	Surfactant protein A is a principal and oxidation-sensitive microbial permeabilizing factor in the alveolar lining fluid.	SFTPA1 SFTPA2	9.28e-07	2	34	2	15890661
Pubmed	Enhanced lung injury and delayed clearance of Pneumocystis carinii in surfactant protein A-deficient mice: attenuation of cytokine responses and reactive oxygen-nitrogen species.	SFTPA1 SFTPA2	9.28e-07	2	34	2	15385504
Pubmed	Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	33141765
Pubmed	A TLR4-interacting SPA4 peptide inhibits LPS-induced lung inflammation.	SFTPA1 SFTPA2	9.28e-07	2	34	2	23475791
Pubmed	Regulatory roles of SP-A and exosomes in pneumonia-induced acute lung and kidney injuries.	SFTPA1 SFTPA2	9.28e-07	2	34	2	37256132
Pubmed	Surfactant protein A associated with respiratory distress syndrome in Korean preterm infants: evidence of ethnic difference.	SFTPA1 SFTPA2	9.28e-07	2	34	2	23038062
Pubmed	Surfactant protein A binds flagellin enhancing phagocytosis and IL-1β production.	SFTPA1 SFTPA2	9.28e-07	2	34	2	24312669
Pubmed	Surfactant protein a attenuates generalized and localized neuroinflammation in neonatal mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	36871846
Pubmed	Correlation analysis between single nucleotide polymorphisms of pulmonary surfactant protein A gene and pulmonary tuberculosis in the Han population in China.	SFTPA1 SFTPA2	9.28e-07	2	34	2	24984162
Pubmed	Innate immunity of surfactant protein A in experimental otitis media.	SFTPA1 SFTPA2	9.28e-07	2	34	2	31378117
Pubmed	Surfactant Protein A, a Novel Regulator for Smooth Muscle Phenotypic Modulation and Vascular Remodeling-Brief Report.	SFTPA1 SFTPA2	9.28e-07	2	34	2	33267655
Pubmed	Effect of cysteine 85 on biochemical properties and biological function of human surfactant protein A variants.	SFTPA1 SFTPA2	9.28e-07	2	34	2	17580966
Pubmed	Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein.	SFTPA1 SFTPA2	9.28e-07	2	34	2	3755136
Pubmed	Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection.	SFTPA1 SFTPA2	9.28e-07	2	34	2	11237812
Pubmed	Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line.	SFTPA1 SFTPA2	9.28e-07	2	34	2	10781424
Pubmed	SP-A is necessary for increased clearance of alveolar DPPC with hyperventilation or secretagogues.	SFTPA1 SFTPA2	9.28e-07	2	34	2	12676766
Pubmed	Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences.	SFTPA1 SFTPA2	9.28e-07	2	34	2	29394894
Pubmed	Surfactant protein-A suppresses eosinophil-mediated killing of Mycoplasma pneumoniae in allergic lungs.	SFTPA1 SFTPA2	9.28e-07	2	34	2	22384248
Pubmed	Surfactant protein A enhances production of secretory leukoprotease inhibitor and protects it from cleavage by matrix metalloproteinases.	SFTPA1 SFTPA2	9.28e-07	2	34	2	19155504
Pubmed	Surfactant Protein A can Affect the Surface Tension of the Eustachian Tube and Macrophage Migration.	SFTPA1 SFTPA2	9.28e-07	2	34	2	36102297
Pubmed	Surfactant protein A deficiency exacerbates renal interstitial fibrosis following obstructive injury in mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	27916681
Pubmed	Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathway.	SFTPA1 SFTPA2	9.28e-07	2	34	2	12959932
Pubmed	Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition.	SFTPA1 SFTPA2	9.28e-07	2	34	2	15044702
Pubmed	Structural comparison of recombinant pulmonary surfactant protein SP-A derived from two human coding sequences: implications for the chain composition of natural human SP-A.	SFTPA1 SFTPA2	9.28e-07	2	34	2	1986781
Pubmed	Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	17307210
Pubmed	Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation.	SFTPA1 SFTPA2	9.28e-07	2	34	2	12740217
Pubmed	Surfactant protein-A plays an important role in lung surfactant clearance: evidence using the surfactant protein-A gene-targeted mouse.	SFTPA1 SFTPA2	9.28e-07	2	34	2	18083768
Pubmed	Structural characterisation of human proteinosis surfactant protein A.	SFTPA1 SFTPA2	9.28e-07	2	34	2	11087951
Pubmed	Surfactant protein A modulates induction of regulatory T cells via TGF-β.	SFTPA1 SFTPA2	9.28e-07	2	34	2	22474025
Pubmed	The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse.	SFTPA1 SFTPA2	9.28e-07	2	34	2	11504713
Pubmed	Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	38553537
Pubmed	Surfactant protein-A inhibits Aspergillus fumigatus-induced allergic T-cell responses.	SFTPA1 SFTPA2	9.28e-07	2	34	2	16120217
Pubmed	SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved.	SFTPA1 SFTPA2	9.28e-07	2	34	2	29202868
Pubmed	The alveolar macrophage toponome of female SP-A knockout mice differs from that of males before and after SP-A1 rescue.	SFTPA1 SFTPA2	9.28e-07	2	34	2	35322074
Pubmed	Surfactant protein A regulates surfactant phospholipid clearance after LPS-induced injury in vivo.	SFTPA1 SFTPA2	9.28e-07	2	34	2	12060563
Pubmed	Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum.	SFTPA1 SFTPA2	9.28e-07	2	34	2	33510368
Pubmed	Surfactant Protein-A Protects against IL-13-Induced Inflammation in Asthma.	SFTPA1 SFTPA2	9.28e-07	2	34	2	32245819
Pubmed	Characteristics of surfactant from SP-A-deficient mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	9700084
Pubmed	Genetic complexity of the human innate host defense molecules, surfactant protein A1 (SP-A1) and SP-A2--impact on function.	SFTPA1 SFTPA2	9.28e-07	2	34	2	19392648
Pubmed	Polymorphisms in the surfactant protein a gene are associated with the susceptibility to recurrent urinary tract infection in chinese women.	SFTPA1 SFTPA2	9.28e-07	2	34	2	20448439
Pubmed	Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products.	SFTPA1 SFTPA2	9.28e-07	2	34	2	20048345
Pubmed	Novel role for surfactant protein A in gastrointestinal graft-versus-host disease.	SFTPA1 SFTPA2	9.28e-07	2	34	2	22508928
Pubmed	Functional assessment and phenotypic heterogeneity of SFTPA1 and SFTPA2 mutations in interstitial lung diseases and lung cancer.	SFTPA1 SFTPA2	9.28e-07	2	34	2	32855221
Pubmed	Surfactant protein A suppresses lipopolysaccharide-induced IL-10 production by murine macrophages.	SFTPA1 SFTPA2	9.28e-07	2	34	2	11342662
Pubmed	Surfactant protein A-deficient mice are susceptible to group B streptococcal infection.	SFTPA1 SFTPA2	9.28e-07	2	34	2	9126996
Pubmed	Relationship between surfactant protein A polymorphisms and allergic rhinitis in a Chinese Han population.	SFTPA1 SFTPA2	9.28e-07	2	34	2	20963503
Pubmed	Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene.	SFTPA1 SFTPA2	9.28e-07	2	34	2	20693318
Pubmed	Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection.	SFTPA1 SFTPA2	9.28e-07	2	34	2	11839553
Pubmed	Type IV pilus glycosylation mediates resistance of Pseudomonas aeruginosa to opsonic activities of the pulmonary surfactant protein A.	SFTPA1 SFTPA2	9.28e-07	2	34	2	25605768
Pubmed	Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene.	BRD3 BRD2	9.28e-07	2	34	2	9373153
Pubmed	Surfactant protein A decreases lung injury and mortality after murine marrow transplantation.	SFTPA1 SFTPA2	9.28e-07	2	34	2	12204891
Pubmed	Type IV pilus of Pseudomonas aeruginosa confers resistance to antimicrobial activities of the pulmonary surfactant protein-A.	SFTPA1 SFTPA2	9.28e-07	2	34	2	24080545
Pubmed	Lung development in the mouse embryo.	SFTPA1 SFTPA2	9.28e-07	2	34	2	2050021
Pubmed	Role of surfactant protein-A in nitric oxide production and mycoplasma killing in congenic C57BL/6 mice.	SFTPA1 SFTPA2	9.28e-07	2	34	2	12959946
Pubmed	Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.	SFTPA1 SFTPA2	9.28e-07	2	34	2	1443158
Pubmed	Surfactant Protein A and B Gene Polymorphisms and Risk of Respiratory Distress Syndrome in Late-Preterm Neonates.	SFTPA1 SFTPA2	9.28e-07	2	34	2	27835691
Pubmed	Surfactant protein-A enhances ureaplasmacidal activity in vitro.	SFTPA1 SFTPA2	9.28e-07	2	34	2	20197455
Pubmed	The role of pulmonary collectin N-terminal domains in surfactant structure, function, and homeostasis in vivo.	SFTPA1 SFTPA2	2.78e-06	3	34	2	12015304
Pubmed	Surfactant protein-A modulates LPS-induced TLR4 localization and signaling via β-arrestin 2.	SFTPA1 SFTPA2	2.78e-06	3	34	2	23536892
Pubmed	Inhibitory effects of surfactant protein A on surfactant phospholipid hydrolysis by secreted phospholipases A2.	SFTPA1 SFTPA2	2.78e-06	3	34	2	12847272
Pubmed	Surfactant proteins SP-A and SP-D: structure, function and receptors.	SFTPA1 SFTPA2	2.78e-06	3	34	2	16213021
Pubmed	Negligible role for pneumococcal surface protein A (PspA) and pneumococcal surface protein C (PspC) in the nasopharyngeal colonization of mice with a serotype 6B pneumococcal strain.	SFTPA1 SFTPA2	2.78e-06	3	34	2	37839762
Pubmed	Surfactant protein A modulates cell surface expression of CR3 on alveolar macrophages and enhances CR3-mediated phagocytosis.	SFTPA1 SFTPA2	2.78e-06	3	34	2	19155216
Pubmed	Interaction of surfactant protein A with peroxiredoxin 6 regulates phospholipase A2 activity.	SFTPA1 SFTPA2	2.78e-06	3	34	2	16330552
Pubmed	Surfactant protein A inhibits lipopolysaccharide-induced in vivo production of interleukin-10 by mononuclear phagocytes during lung inflammation.	SFTPA1 SFTPA2	2.78e-06	3	34	2	12594061
Pubmed	Macrophage-independent fungicidal action of the pulmonary collectins.	SFTPA1 SFTPA2	2.78e-06	3	34	2	12857753
Pubmed	Lung surfactant proteins involved in innate immunity.	SFTPA1 SFTPA2	2.78e-06	3	34	2	10047533
Pubmed	Surfactant protein-A inhibits mycoplasma-induced dendritic cell maturation through regulation of HMGB-1 cytokine activity.	SFTPA1 SFTPA2	2.78e-06	3	34	2	20810986
Pubmed	Altered surfactant function and structure in SP-A gene targeted mice.	SFTPA1 SFTPA2	2.78e-06	3	34	2	8790375
Pubmed	Role of surfactant proteins A and D in sepsis-induced acute kidney injury.	SFTPA1 SFTPA2	2.78e-06	3	34	2	25255378
Pubmed	Pulmonary collectins modulate strain-specific influenza a virus infection and host responses.	SFTPA1 SFTPA2	2.78e-06	3	34	2	15280465
Pubmed	Foetal lung maturation in 11beta-hydroxysteroid dehydrogenase type 1 knockout mice.	SFTPA1 SFTPA2	2.78e-06	3	34	2	12439781
Cytoband	10q22.3	SFTPA1 SFTPA2	4.72e-04	43	34	2	10q22.3
Cytoband	18q11.2	NPC1 ABHD3	5.64e-04	47	34	2	18q11.2
Cytoband	9q34	BRD3 NTNG2	7.44e-04	54	34	2	9q34
Cytoband	Ensembl 112 genes in cytogenetic band chr18q11	NPC1 ABHD3	1.83e-03	85	34	2	chr18q11
GeneFamily	Collectins	SFTPA1 SFTPA2	5.75e-05	10	21	2	491
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SFTPA1 SFTPA2	1.03e-03	41	21	2	1298
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPC1 SFTPA1 SFTPA2 DHCR24	7.25e-06	164	34	4	b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPC1 SFTPA1 SFTPA2 DHCR24	7.25e-06	164	34	4	3aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell	facs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD3 MMEL1 SLFN14 TSPAN33	7.42e-06	165	34	4	4f95c2fe5ab4416c736fe0d1936695a2b26777eb
ToppCell	facs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD3 MMEL1 SLFN14 TSPAN33	7.42e-06	165	34	4	3e913b49a868fdd5589200ae3e9be77c0938ba14
ToppCell	Epithelial-Epithelial-C_(AT2)\|Epithelial / shred on cell class and cell subclass (v4)	NPC1 CHSY1 SFTPA1 TCN1	8.95e-06	173	34	4	f57cbf5bd2a9e5db47b4919e9cd5e50781c1a990
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NPC1 TRPM6 SFTPA1 TCN1	1.32e-05	191	34	4	1cd4d513ac363fdda07030b85a88174d29af3588
ToppCell	ASK440-Epithelial-Type_2\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	NPC1 SFTPA1 SFTPA2 DHCR24	1.49e-05	197	34	4	08d5bbeb77a4152af1c783bc958afcae24667767
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RASGEF1A MMEL1 SLFN14 TSPAN33	1.55e-05	199	34	4	b68648b4559e452656dc9e6a0974233e842f5e0d
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 NBEAL1 DHCR24	1.55e-05	199	34	4	f80e2277fad4aa7bda957c88b18ec3a159c9c79d
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 NBEAL1 DHCR24	1.55e-05	199	34	4	e3ba03c48b58b35e22de51c69ea22b46e2c20423
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DEPDC5 CPD GLP1R	1.35e-04	131	34	3	7346d4121063cbe100505c81a5f0bc612150064a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DEPDC5 CPD GLP1R	1.58e-04	138	34	3	a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 ADGRL2 DYNC2H1	1.64e-04	140	34	3	5e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCell	COVID-19-Mast_cells-Dendritic_cells\|COVID-19 / group, cell type (main and fine annotations)	BRD3 SLFN14 TSPAN33	1.68e-04	141	34	3	0fc06c2325249aa4ae65c0ace1ec3f953372f2e4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 ADGRL2 DYNC2H1	1.71e-04	142	34	3	5b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCell	E15.5-Hematopoietic-Erythroid-enucleate_erythrocyte\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NTNG2 SLFN14 TSPAN33	1.75e-04	143	34	3	e4207ff9e8248813356631631bbf31a63f23ad3c
ToppCell	E15.5-Hematopoietic-Erythroid\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NTNG2 SLFN14 TSPAN33	1.75e-04	143	34	3	15a7b93c381ef0f455f99f3abf4b2b9454d35bc4
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TRPM6 SFTPA1 TCN1	2.22e-04	155	34	3	9cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCell	390C-Lymphocytic-Plasma_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	IGLV3-1 GNB3 APOBEC3B	2.26e-04	156	34	3	0de2fc695bd5f8d4633c514f71ea941c88137bac
ToppCell	390C-Lymphocytic-Plasma_cell-\|390C / Donor, Lineage, Cell class and subclass (all cells)	IGLV3-1 GNB3 APOBEC3B	2.26e-04	156	34	3	4f92ca30755430db44402afc603d1ecd8bfc3617
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMEL1 SLFN14 TSPAN33	2.35e-04	158	34	3	0edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMEL1 SLFN14 TSPAN33	2.35e-04	158	34	3	9fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	2.44e-04	160	34	3	731def6d82814ebac1a400bc7aea5f6da43ec960
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	2.44e-04	160	34	3	b81d218c20fe37921cf3c6c7db2da3bfd367230a
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	2.44e-04	160	34	3	cf27b4ac4d0caa6f9b068dc8ea93472470a01a4d
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	2.44e-04	160	34	3	ac5d573c135d66d6adddd42dfddd9d3e01532172
ToppCell	368C-Epithelial_cells-Epithelial-A_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	2.62e-04	164	34	3	85f53d184fa70e3eb1af655807f32b17ddbfb304
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	2.62e-04	164	34	3	beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell	normal_Lung-Epithelial_cells-Undetermined\|normal_Lung / Location, Cell class and cell subclass	SFTPA1 SFTPA2 DHCR24	2.62e-04	164	34	3	fa2dae15b38cb8f9642dbf00549beec8ee19e9bb
ToppCell	368C-Epithelial_cells-Epithelial-A_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	2.62e-04	164	34	3	144ba070a1ede71684224cc6d4ead3b7e6a7b4c6
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	2.62e-04	164	34	3	d005cfd821b87548b075120bffe65a0be9860463
ToppCell	390C-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGLV3-1 GNB3 APOBEC3B	2.71e-04	166	34	3	4ba3711a02d3695b27f7cefd7c60e3be009f5bef
ToppCell	390C-Lymphocytic-Plasma_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGLV3-1 GNB3 APOBEC3B	2.71e-04	166	34	3	35f6ae2664935dda0d883b32a050ced843204f2d
ToppCell	Club-club-2\|World / Class top	OAS2 SFTPA1 BRD2	2.71e-04	166	34	3	56f11efb6b686b3ee2c34a051f626e3d761b5112
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 RASGEF1A DEPDC5	2.76e-04	167	34	3	774f3264318b002d0df5d06d41d645366038d0bf
ToppCell	metastatic_Brain-B_lymphocytes-Plasma_cells\|metastatic_Brain / Location, Cell class and cell subclass	IGLV3-1 SFTPA1 SFTPA2	2.91e-04	170	34	3	53634da9e9c72f6400639954c286c6e38ea5a188
ToppCell	CTRL-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	TRPM6 CHSY1 CPD	2.91e-04	170	34	3	151dabe1d240dde414c881bf4fa816c69fa1c32d
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	3.01e-04	172	34	3	a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|367C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	3.01e-04	172	34	3	26006967d0c82f7bd9b36a18e97a1b93e856aa67
ToppCell	CTRL-Myeloid-Neutrophil\|CTRL / Disease state, Lineage and Cell class	TRPM6 CHSY1 CPD	3.01e-04	172	34	3	ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial-AT2\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NPC1 SFTPA1 TCN1	3.06e-04	173	34	3	f6e36ea98a9c669ff393d141455aaecef083f738
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 ADGRL2 DYNC2H1	3.27e-04	177	34	3	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 SFTPA1 TCN1	3.33e-04	178	34	3	76e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCell	droplet-Lung-30m-Epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 SFTPA1 TCN1	3.33e-04	178	34	3	5442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 SFTPA1 TCN1	3.33e-04	178	34	3	82f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 SFTPA1 TCN1	3.33e-04	178	34	3	523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCell	Children_(3_yrs)\|World / Lineage, Cell type, age group and donor	SFTPA1 FLVCR2 SFTPA2	3.33e-04	178	34	3	df2ecd3214590b914f2762db57efe780ba038db3
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	3.38e-04	179	34	3	466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell	10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NTNG2 TRBV19 TCN1	3.38e-04	179	34	3	d16dc58b5b22762a5a3c875563ced18022d08908
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	3.38e-04	179	34	3	f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 ADGRL2 DYNC2H1	3.38e-04	179	34	3	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	droplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.50e-04	181	34	3	cadb18fc73031eb9f779599e15cd7861337fee78
ToppCell	AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SFTPA1 SFTPA2 DHCR24	3.50e-04	181	34	3	ed0ea67f0607073aedf153f8d1073b35e46127c3
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.50e-04	181	34	3	85bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCell	droplet-Lung-nan-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.55e-04	182	34	3	cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFTPA1 TCN1 GLP1R	3.55e-04	182	34	3	81c394959414173016426961478f670cd822f8b3
ToppCell	droplet-Lung-nan-21m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.55e-04	182	34	3	40539ade8c3cd12b61f1cd0d493828e58282796b
ToppCell	droplet-Lung-nan-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.55e-04	182	34	3	7e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCell	droplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.55e-04	182	34	3	d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFTPA1 TCN1 GLP1R	3.55e-04	182	34	3	41a7543c8b703441ff6ac2307faffe5f798b2c41
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 ADGRL2 DYNC2H1	3.55e-04	182	34	3	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	PND07-28-samps-Epithelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TRPM6 SFTPA1 TCN1	3.61e-04	183	34	3	a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCell	COVID-19-Epithelial_cells-ECM-high_epithelial\|COVID-19 / group, cell type (main and fine annotations)	SFTPA1 SFTPA2 DHCR24	3.61e-04	183	34	3	dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell	PND07-28-samps-Epithelial-Alveolar_epithelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TRPM6 SFTPA1 TCN1	3.61e-04	183	34	3	23e55f88a802a9299d2773f9394970e86e8bbfaa
ToppCell	PND07-28-samps-Epithelial-Alveolar_epithelial-AT2\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TRPM6 SFTPA1 TCN1	3.61e-04	183	34	3	0a69e22750dd8b66ab988cf36d0dd2b59e2f7d26
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 ADGRL2 DYNC2H1	3.61e-04	183	34	3	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	droplet-Lung-1m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFTPA1 TCN1 CHRNB1	3.67e-04	184	34	3	24cbe9f2461ea920954e44bf3b2c2a6a5d4debfb
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	3.67e-04	184	34	3	0ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell	droplet-Lung-1m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFTPA1 TCN1 CHRNB1	3.67e-04	184	34	3	98079fd048a63b51bbdf3833b6f15bf0ae99ea90
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	SFTPA1 SFTPA2 DHCR24	3.67e-04	184	34	3	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	droplet-Lung-1m-Epithelial-alveolar_epithelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFTPA1 TCN1 CHRNB1	3.67e-04	184	34	3	86c1551c4f7c7d0c35c14852b01b1e602fa5092a
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TRPM6 CPD NTNG2	3.67e-04	184	34	3	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	3.67e-04	184	34	3	2a8338e94937686a148b5433515700ca0f674058
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNLT2B IK DYNC2H1	3.67e-04	184	34	3	2df903924df9cb71039159416bcbe6a6614e21fe
ToppCell	normal-na-Lymphocytic-lymphocyte-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	DEPDC5 DHCR24 NEMP2	3.67e-04	184	34	3	2c286712428662bc4589dc5ac4011bf7ed403cb5
ToppCell	droplet-Lung-nan-21m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.73e-04	185	34	3	0e7351cd6d6e6e8c29573042e168da50ee496cfc
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPC1 CHSY1 SFTPA1	3.73e-04	185	34	3	fd51fef8c69e34c72017d8371ab0a0d7be5701f2
ToppCell	PND01-03-samps-Epithelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	TRPM6 SFTPA1 TCN1	3.73e-04	185	34	3	2b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPC1 CHSY1 SFTPA1	3.73e-04	185	34	3	bea26e369ae91006052b973cd89b4c49afa9e553
ToppCell	droplet-Lung-nan-21m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.73e-04	185	34	3	6938ac3cab536cf8a474eba441ce6dcdfcc43b53
ToppCell	AT2_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	SFTPA1 SFTPA2 DHCR24	3.73e-04	185	34	3	3b3268e3f99121124e33086cac88479808d31630
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	SFTPA1 SFTPA2 DHCR24	3.73e-04	185	34	3	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFTPA2 NBEAL1 DHCR24	3.73e-04	185	34	3	7460387f48f33674330bd53b759681b264228f5a
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.79e-04	186	34	3	3c4994a1a7db06a61da8170e45e06aaef7896592
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	OAS2 FLVCR2 ADGRL2	3.79e-04	186	34	3	a906020a8df6fcca474b278f746c553b177a56b4
ToppCell	facs-Lung-EPCAM-24m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.79e-04	186	34	3	a583d6fc0f1e729f6e9fd18d7b49d6eab9ca32b9
ToppCell	15-Trachea-Epithelial-Secretory_progenitor\|Trachea / Age, Tissue, Lineage and Cell class	SFTPA1 SFTPA2 DHCR24	3.85e-04	187	34	3	be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	3.85e-04	187	34	3	11670a85db87cbb3e78022a589632173604b0940
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	NPC1 SFTPA1 SFTPA2	3.85e-04	187	34	3	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CPD DYNC2H1 DHCR24	3.85e-04	187	34	3	8c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCell	SMG-Goblet\|World / shred by cell class for bronchial biopsy	CPD SFTPA2 TCN1	3.85e-04	187	34	3	5178118bdec91495253c88f58fd908cf831de7ef
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 ADGRL2 DYNC2H1	3.85e-04	187	34	3	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	TRPM6 SFTPA1 TCN1	3.85e-04	187	34	3	23fe3cdd6cc9b067086a8392d104186d300298ea
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA1 SFTPA2 DHCR24	3.85e-04	187	34	3	0277d4e54bd4d48f30241c2951a569209423fee8
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 SFTPA1 TCN1	3.91e-04	188	34	3	068b761a7b6778bc6d6c776b5f09094aac87477e
ToppCell	facs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.91e-04	188	34	3	3dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 SFTPA1 TCN1	3.91e-04	188	34	3	c95134245dab9057eb1f9b54acb371470f9c8b86
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 SFTPA1 TCN1	3.91e-04	188	34	3	3ee321a74f04eb0982c7b4977426946b0ae6e5a9
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SFTPA1 TCN1	3.91e-04	188	34	3	b1049003ca79c340bb8c78da66bdc0956e1aebc2
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SFTPA1 SFTPA2 DHCR24	3.91e-04	188	34	3	c9cdee6f8d42ee69f5fb335f25084603c511bd29
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SFTPA1 SFTPA2 DHCR24	2.03e-04	50	25	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_31_ALVEOLAR
Drug	Liraglutide	SFTPA1 GLP1R	6.11e-06	3	33	2	ctd:D000069450
Drug	Famprofazone [22881-35-2]; Up 200; 10.6uM; PC3; HT_HG-U133A	TRPM6 DEPDC5 CLEC4M ADGRL2 CHRNB1	8.55e-06	195	33	5	4309_UP
Disease	level of leukocyte immunoglobulin-like receptor subfamily B member 4 in blood serum	SFTPA1 SFTPA2	1.21e-05	5	33	2	OBA_2042200
Disease	level of prosaposin in blood serum	SFTPA1 SFTPA2	1.21e-05	5	33	2	OBA_2044552
Disease	newborn respiratory distress syndrome (biomarker_via_orthology)	SFTPA1 SFTPA2	1.81e-05	6	33	2	DOID:12716 (biomarker_via_orthology)
Disease	newborn respiratory distress syndrome (is_implicated_in)	SFTPA1 SFTPA2	2.54e-05	7	33	2	DOID:12716 (is_implicated_in)
Disease	asphyxiating thoracic dystrophy (is_implicated_in)	DYNLT2B DYNC2H1	2.54e-05	7	33	2	DOID:0050592 (is_implicated_in)
Disease	leukocyte immunoglobulin-like receptor subfamily B member 4 measurement	SFTPA1 SFTPA2	3.38e-05	8	33	2	EFO_0801768
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	SFTPA1 SFTPA2	7.95e-05	12	33	2	EFO_0801493
Disease	granulins measurement	SFTPA1 SFTPA2	7.95e-05	12	33	2	EFO_0008141
Disease	Short Rib-Polydactyly Syndrome	DYNLT2B DYNC2H1	9.39e-05	13	33	2	C0036996
Disease	Hamman-Rich syndrome	SFTPA1 SFTPA2	1.09e-04	14	33	2	C0085786
Disease	Saldino-Noonan Syndrome	DYNLT2B DYNC2H1	1.09e-04	14	33	2	C0036069
Disease	Majewski Syndrome	DYNLT2B DYNC2H1	1.09e-04	14	33	2	C0024507
Disease	bacterial pneumonia (biomarker_via_orthology)	SFTPA1 SFTPA2	1.09e-04	14	33	2	DOID:874 (biomarker_via_orthology)
Disease	neutrophil count, basophil count	NPC1 CHSY1 BRD3 CLEC4M	1.11e-04	224	33	4	EFO_0004833, EFO_0005090
Disease	Familial Idiopathic Pulmonary Fibrosis	SFTPA1 SFTPA2	2.28e-04	20	33	2	C4721952
Disease	Idiopathic Pulmonary Fibrosis	SFTPA1 SFTPA2	2.51e-04	21	33	2	C1800706
Disease	Polydactyly	DYNLT2B DYNC2H1 CEP164	3.04e-04	117	33	3	C0152427
Disease	von Willebrand factor measurement, coronary artery disease	CLEC4M NBEAL1 DYNC2H1	3.12e-04	118	33	3	EFO_0001645, EFO_0004629
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	SFTPA1 SFTPA2	3.30e-04	24	33	2	DOID:3827 (biomarker_via_orthology)
Disease	selenium measurement	ADGRL2 DYNC2H1	4.83e-04	29	33	2	EFO_0006331
Disease	unipolar depression, bipolar disorder, seasonality measurement	SFTPA1 SFTPA2	5.17e-04	30	33	2	EFO_0003761, EFO_0006876, MONDO_0004985
Disease	obesity (biomarker_via_orthology)	SFTPA1 SFTPA2 GLP1R	5.92e-04	147	33	3	DOID:9970 (biomarker_via_orthology)
Disease	glucagon measurement	SFTPA1 SFTPA2 ADGRL2	6.78e-04	154	33	3	EFO_0008463
Disease	lung disease (biomarker_via_orthology)	SFTPA1 SFTPA2	7.05e-04	35	33	2	DOID:850 (biomarker_via_orthology)
Disease	cholesteryl ester 16:0 measurement	NTNG2 DYNC2H1	7.46e-04	36	33	2	EFO_0010341
Disease	pulmonary tuberculosis (is_implicated_in)	SFTPA1 CLEC4M	1.02e-03	42	33	2	DOID:2957 (is_implicated_in)
Disease	Adult Medulloblastoma	BRD3 BRD2	1.06e-03	43	33	2	C0278876
Disease	Childhood Medulloblastoma	BRD3 BRD2	1.06e-03	43	33	2	C0278510
Disease	Melanotic medulloblastoma	BRD3 BRD2	1.06e-03	43	33	2	C1275668
Disease	Medullomyoblastoma	BRD3 BRD2	1.06e-03	43	33	2	C0205833
Disease	Desmoplastic Medulloblastoma	BRD3 BRD2	1.06e-03	43	33	2	C0751291
Disease	Gastric Adenocarcinoma	BRD3 BRD2	1.17e-03	45	33	2	C0278701
Disease	Medulloblastoma	BRD3 BRD2	1.44e-03	50	33	2	C0025149
Disease	neutrophil count, eosinophil count	NPC1 CHSY1 CLEC4M	1.72e-03	213	33	3	EFO_0004833, EFO_0004842
Disease	coronary artery disease	NPC1 SFTPA1 SFTPA2 ADGRL2 NBEAL1 DYNC2H1	1.88e-03	1194	33	6	EFO_0001645
Disease	asthma (biomarker_via_orthology)	SFTPA1 SFTPA2	1.99e-03	59	33	2	DOID:2841 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ENNYYWSASECMQDF	BRD3	91	Q15059
TIMDYEEFAYCWENF	APOBEC3B	146	Q9UH17
DWQNCTMVFSSYSYD	CHRNB1	161	P11230
SLDWFDNDNSTCYMD	ABHD3	121	Q8WU67
DNYFNANCSFWNYSE	ADGRL2	781	O95490
EDFQEYCNSNEWQVY	NBEAL1	1671	Q6ZS30
QNMFCEERVGYNWAY	DEPDC5	1536	O75140
TQAMDEADYYCQAWD	IGLV3-1	96	P01715
YEDEGCWTRNSNMNY	GLP1R	291	P43220
DCYCYNQNSQVEWKY	NEMP2	51	A6NFY4
FAGYDDFNCNVWDSM	GNB3	286	P16520
EQSECMIYQYGNYSW	MMEL1	646	Q495T6
LCIYWMVNYNFEDET	OAS2	261	P29728
YFMEHVAAECSTWNY	METTL7A	171	Q9H8H3
ADACNATNWIEYMFN	NPC1	181	O15118
ALWRTYYNNSMCEQE	DYNC2H1	3646	Q8NCM8
GLVFCMEYFANNFDW	GPN3	76	Q9UHW5
MEYFANNFDWLENCL	GPN3	81	Q9UHW5
YADCYMNREEFWEMF	DHCR24	471	Q15392
EGGMQDYNYVWANCF	CPD	331	O75976
FSCYSMCNSFQWIQY	FLVCR2	91	Q9UPI3
FMASRCFWDADTDNY	DYNLT2B	106	Q8WW35
WQPYQFYAEDCMEAF	NTNG2	161	Q96CW9
MDETENFCSKYGNWY	SLFN14	661	P0C7P3
EMYTDGQWNDRNCLY	SFTPA2	226	Q8IWL1
EMYTDGQWNDRNCLY	SFTPA1	226	Q8IWL2
ENNYYWAASECMQDF	BRD2	131	P25440
DIYYFNFANGQSMWD	CEP164	71	Q9UPV0
QCVWSYEMQQLFYEN	CHSY1	266	Q86X52
DWTFFQGNCYFMSNS	CLEC4M	271	Q9H2X3
SYKDWSQNMYFNCSE	TSPAN33	161	Q86UF1
DFQFMWYYSDQNASS	TRPM6	776	Q9BX84
YSLEAYDNWFNCLSM	RASGEF1A	261	Q8N9B8
LFVSSDYYNENDWNC	TCN1	251	P20061
WDFDTQEEYSEYMNN	IK	481	Q13123
SCEQNLNHDAMYWYR	TRBV19	41	A0A075B6N1