Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

3.21e-0846405GO:0030020
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1 SSPOP

1.89e-06188406GO:0005201
GeneOntologyMolecularFunctioncomplement receptor activity

CR1 CR2

3.51e-0414402GO:0004875
GeneOntologyMolecularFunctionstructural molecule activity

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1 BSN SSPOP

1.77e-03891407GO:0005198
GeneOntologyMolecularFunctioncomplement binding

CR1 CR2

1.87e-0332402GO:0001848
GeneOntologyBiologicalProcesscomplement activation

COLEC11 C8B CR1 CR2 FCN2

2.65e-0770415GO:0006956
GeneOntologyBiologicalProcesscomplement activation, alternative pathway

C8B CR1 CR2

6.91e-0619413GO:0006957
GeneOntologyBiologicalProcesscomplement activation, classical pathway

C8B CR1 CR2

9.12e-0544413GO:0006958
GeneOntologyBiologicalProcessextracellular matrix organization

ADAMTS17 COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

9.38e-05377416GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

ADAMTS17 COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

9.52e-05378416GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

ADAMTS17 COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

9.66e-05379416GO:0045229
GeneOntologyBiologicalProcessnegative regulation of complement activation, classical pathway

CR1 CR2

1.07e-048412GO:0045959
GeneOntologyBiologicalProcesspositive regulation of opsonization

COLEC11 FCN2

1.38e-049412GO:1903028
GeneOntologyBiologicalProcessregulation of complement activation, classical pathway

CR1 CR2

1.72e-0410412GO:0030450
GeneOntologyBiologicalProcessregulation of opsonization

COLEC11 FCN2

2.10e-0411412GO:1903027
GeneOntologyBiologicalProcessnegative regulation of humoral immune response mediated by circulating immunoglobulin

CR1 CR2

2.51e-0412412GO:0002924
GeneOntologyBiologicalProcesscomplement activation, lectin pathway

COLEC11 FCN2

2.51e-0412412GO:0001867
GeneOntologyBiologicalProcesshumoral immune response mediated by circulating immunoglobulin

C8B CR1 CR2

2.54e-0462413GO:0002455
GeneOntologyBiologicalProcessnegative regulation of complement activation

CR1 CR2

3.46e-0414412GO:0045916
GeneOntologyBiologicalProcesshumoral immune response

COLEC11 C8B CR1 CR2 FCN2

4.19e-04321415GO:0006959
GeneOntologyBiologicalProcessnegative regulation of immunoglobulin mediated immune response

CR1 CR2

4.55e-0416412GO:0002890
GeneOntologyBiologicalProcesscomplement receptor mediated signaling pathway

CR1 CR2

4.55e-0416412GO:0002430
GeneOntologyBiologicalProcessnegative regulation of B cell mediated immunity

CR1 CR2

4.55e-0416412GO:0002713
GeneOntologyBiologicalProcessnegative regulation of humoral immune response

CR1 CR2

6.45e-0419412GO:0002921
GeneOntologyBiologicalProcessopsonization

COLEC11 FCN2

6.45e-0419412GO:0008228
GeneOntologyBiologicalProcessregulation of humoral immune response mediated by circulating immunoglobulin

CR1 CR2

8.68e-0422412GO:0002923
GeneOntologyBiologicalProcesspositive regulation of phagocytosis

COLEC11 SFTPA2 FCN2

1.00e-0399413GO:0050766
GeneOntologyCellularComponentcollagen trimer

COL4A3 COLEC11 C1QTNF2 COL22A1 GLDN COL12A1 COL13A1 SFTPA2 COL19A1 FCN2

5.93e-16883910GO:0005581
GeneOntologyCellularComponentcollagen-containing extracellular matrix

ADAMTS17 COL4A3 COL22A1 COL12A1 COL13A1 SFTPA2 COL19A1 SSPOP FCN2

4.35e-07530399GO:0062023
GeneOntologyCellularComponentextracellular matrix

ADAMTS17 COL4A3 COL22A1 COL12A1 COL13A1 SFTPA2 COL19A1 SSPOP FCN2

2.55e-06656399GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS17 COL4A3 COL22A1 COL12A1 COL13A1 SFTPA2 COL19A1 SSPOP FCN2

2.61e-06658399GO:0030312
GeneOntologyCellularComponentbeta-catenin-TCF complex

BCL9L PYGO2

2.61e-0413392GO:1990907
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

3.62e-04332395GO:0005788
GeneOntologyCellularComponentserine-type endopeptidase complex

COLEC11 FCN2

6.31e-0420392GO:1905370
GeneOntologyCellularComponentserine-type peptidase complex

COLEC11 FCN2

7.65e-0422392GO:1905286
GeneOntologyCellularComponentchromatin

DMRTC2 SIX5 CSRNP1 IRX5 PHOX2B EN2 IRX2 ZNF446

5.28e-031480398GO:0000785
DomainCollagen

COL4A3 COLEC11 C1QTNF2 COL22A1 GLDN COL12A1 COL13A1 SFTPA2 COL19A1 FCN2

1.67e-15854010PF01391
DomainCollagen

COL4A3 COLEC11 C1QTNF2 COL22A1 GLDN COL12A1 COL13A1 SFTPA2 COL19A1 FCN2

1.67e-15854010IPR008160
DomainTSPN

COL22A1 COL12A1 COL19A1

1.56e-0523403SM00210
DomainHomeobox_CS

SIX5 IRX5 PHOX2B EN2 IRX2

4.60e-05186405IPR017970
DomainIRO

IRX5 IRX2

6.67e-056402SM00548
DomainIroquois_homeo

IRX5 IRX2

6.67e-056402IPR003893
DomainHomeobox

SIX5 IRX5 PHOX2B EN2 IRX2

1.36e-04234405PF00046
DomainHOMEOBOX_1

SIX5 IRX5 PHOX2B EN2 IRX2

1.42e-04236405PS00027
DomainHOX

SIX5 IRX5 PHOX2B EN2 IRX2

1.44e-04237405SM00389
DomainHomeobox_dom

SIX5 IRX5 PHOX2B EN2 IRX2

1.50e-04239405IPR001356
DomainHOMEOBOX_2

SIX5 IRX5 PHOX2B EN2 IRX2

1.50e-04239405PS50071
DomainLaminin_G

COL22A1 COL12A1 COL19A1

2.59e-0458403IPR001791
Domain-

SIX5 IRX5 PHOX2B EN2 IRX2

3.29e-042834051.10.10.60
DomainTSP_1

ADAMTS17 C8B SSPOP

3.31e-0463403PF00090
DomainTSP1

ADAMTS17 C8B SSPOP

3.63e-0465403SM00209
DomainTSP1_rpt

ADAMTS17 C8B SSPOP

3.63e-0465403IPR000884
DomainTSP1

ADAMTS17 C8B SSPOP

3.63e-0465403PS50092
DomainHomeobox_KN

IRX5 IRX2

5.96e-0417402PF05920
DomainHomeobox_KN_domain

IRX5 IRX2

5.96e-0417402IPR008422
DomainHomeodomain-like

SIX5 IRX5 PHOX2B EN2 IRX2

6.80e-04332405IPR009057
DomainCTDL_fold

COL4A3 COLEC11 SFTPA2

1.55e-03107403IPR016187
DomainLDLR_class-A_CS

C8B SSPOP

3.31e-0340402IPR023415
DomainC-type_lectin_CS

COLEC11 SFTPA2

3.82e-0343402IPR018378
DomainLdl_recept_a

C8B SSPOP

4.18e-0345402PF00057
DomainLDLRA_1

C8B SSPOP

4.74e-0348402PS01209
DomainLDrepeatLR_classA_rpt

C8B SSPOP

4.94e-0349402IPR002172
DomainLDLa

C8B SSPOP

4.94e-0349402SM00192
DomainLDLRA_2

C8B SSPOP

4.94e-0349402PS50068
DomainSushi

CR1 CR2

5.54e-0352402PF00084
DomainCCP

CR1 CR2

5.97e-0354402SM00032
DomainSUSHI

CR1 CR2

6.40e-0356402PS50923
DomainVWA

COL22A1 COL12A1

6.40e-0356402PF00092
DomainSushi_SCR_CCP_dom

CR1 CR2

6.63e-0357402IPR000436
Domain-

COL22A1 COL12A1

1.10e-02744023.40.50.410
DomainConA-like_dom

COL22A1 COL12A1 COL19A1

1.14e-02219403IPR013320
DomainC_TYPE_LECTIN_1

COLEC11 SFTPA2

1.27e-0280402PS00615
DomainVWFA

COL22A1 COL12A1

1.33e-0282402PS50234
DomainVWA

COL22A1 COL12A1

1.40e-0284402SM00327
DomainLectin_C

COLEC11 SFTPA2

1.40e-0284402PF00059
DomainCLECT

COLEC11 SFTPA2

1.40e-0284402SM00034
DomainC_TYPE_LECTIN_2

COLEC11 SFTPA2

1.43e-0285402PS50041
DomainC-type_lectin-like

COLEC11 SFTPA2

1.46e-0286402IPR001304
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

2.18e-0841305MM15538
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

3.15e-0844305M27812
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.68e-0761305MM14637
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

2.71e-0767305M26999
PathwayREACTOME_COLLAGEN_FORMATION

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

5.11e-0776305MM14573
PathwayREACTOME_COLLAGEN_FORMATION

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.19e-0690305M631
PathwayWP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY

COLEC11 C8B CR1 CR2 FCN2

2.68e-06106305M42535
PathwayREACTOME_COMPLEMENT_CASCADE

COLEC11 C8B CR1 CR2 FCN2

4.01e-06115305M19752
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A3 COL12A1 COL13A1 COL19A1

4.54e-0653304MM14566
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A3 COL12A1 COL13A1 COL19A1

9.69e-0664304M26953
PathwayREACTOME_COMPLEMENT_CASCADE

COLEC11 C8B CR2 FCN2

2.86e-0584304MM14653
PathwayWP_COMPLEMENT_SYSTEM

SFTPA2 CR1 CR2 FCN2

4.83e-0596304M39581
PathwayKEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_N_TO_LECTIN_PATHWAY_OF_COAGULATION_CASCADE

COLEC11 FCN2

6.53e-056302M47785
PathwayREACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION

COLEC11 FCN2

9.13e-057302MM14654
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A3 COL12A1 COL13A1 COL19A1

9.45e-05114304MM14571
PathwayKEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_PROTHROMBIN_TO_THROMBIN

COLEC11 FCN2

1.22e-048302M47784
PathwayREACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION

COLEC11 FCN2

1.22e-048302M27005
PathwayPID_SYNDECAN_1_PATHWAY

COL4A3 COL12A1 COL13A1

1.24e-0446303M198
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.94e-04258305MM14572
PathwayKEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_FIBRINOGEN_TO_FIBRIN

COLEC11 FCN2

1.95e-0410302M47879
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A3 COL12A1 COL13A1 COL19A1

2.09e-04140304M587
PathwayKEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION

COLEC11 FCN2

2.38e-0411302M47874
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

3.89e-04300305M610
PathwayBIOCARTA_BLYMPHOCYTE_PATHWAY

CR1 CR2

3.92e-0414302M1473
PathwayKEGG_COMPLEMENT_AND_COAGULATION_CASCADES

C8B CR1 CR2

4.14e-0469303M16894
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL4A3 COL12A1 COL13A1

5.09e-0474303M160
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L PYGO2

1.38e-0326302MM14793
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS17 SSPOP

3.09e-0339302M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS17 SSPOP

3.09e-0339302MM15165
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

BCL9L PYGO2

3.58e-0342302M27272
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A3 COL12A1

5.03e-0350302MM14796
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

COLEC11 FCN2

5.85e-0354302MM14655
Pubmed

Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes.

CR1 CR2

1.36e-06241214635039
Pubmed

The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells.

CR1 CR2

1.36e-06241211981823
Pubmed

Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity.

CR1 CR2

1.36e-06241237833411
Pubmed

[THE COMBINATION OF EXPRESSION OF MARKERS CR1 AND CR2 (CD35/CD21) IN DIAGNOSTIC OF B-CELL LYMPHOPROLIFERATIVE DISEASES].

CR1 CR2

1.36e-06241226189291
Pubmed

Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization.

CR1 CR2

1.36e-06241223440418
Pubmed

Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13.

COL12A1 COL19A1

1.36e-0624129143499
Pubmed

miRNA-Processing Gene Methylation and Cancer Risk.

TNRC6B DROSHA

1.36e-06241229475968
Pubmed

Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.

CR1 CR2

1.36e-0624121708808
Pubmed

Comparative functional evolution of human and mouse CR1 and CR2.

CR1 CR2

1.36e-06241218713965
Pubmed

Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes.

CR1 CR2

4.06e-0634127690834
Pubmed

Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.

CR1 CR2

4.06e-0634127528766
Pubmed

A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.

CR1 CR2

4.06e-0634123782802
Pubmed

The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.

CR1 CR2

4.06e-0634122139460
Pubmed

Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor.

BCL9L PYGO2

4.06e-06341220637214
Pubmed

Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry.

CR1 CR2

4.06e-0634122528587
Pubmed

Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.

C8B CR1 CR2

6.68e-063141319344414
Pubmed

Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.

C8B CR1 CR2

7.36e-063241318842294
Pubmed

Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.

CR1 CR2

8.12e-06441216127466
Pubmed

Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.

COLEC11 FCN2

8.12e-06441228739878
Pubmed

Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma.

CR1 CR2

8.12e-06441230217731
Pubmed

Deciphering complement receptor type 1 interactions with recognition proteins of the lectin complement pathway.

CR1 FCN2

8.12e-06441223460739
Pubmed

Collagen XIII induced in vascular endothelium mediates alpha1beta1 integrin-dependent transmigration of monocytes in renal fibrosis.

COL4A3 COL13A1

8.12e-06441220864678
Pubmed

Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes.

IRX5 IRX2

8.12e-06441211435706
Pubmed

Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models.

BCL9L PYGO2

1.35e-05541230760710
Pubmed

Expression of two novel mouse Iroquois homeobox genes during neurogenesis.

IRX5 IRX2

1.35e-05541210704856
Pubmed

Complement-dependent P-selectin expression and injury following ischemic stroke.

CR1 CR2

1.35e-05541217082645
Pubmed

Iroquois genes influence proximo-distal morphogenesis during rat lung development.

IRX5 IRX2

1.35e-05541216299054
Pubmed

LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction.

BCL9L PYGO2

1.35e-05541224360964
Pubmed

TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex.

BCL9L PYGO2

1.35e-05541232808927
Pubmed

Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.

CR1 CR2

1.35e-05541220962256
Pubmed

BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling.

BCL9L PYGO2

2.03e-05641217113272
Pubmed

Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos.

IRX5 IRX2

2.03e-05641220408909
Pubmed

Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development.

BCL9L PYGO2

2.03e-05641225184676
Pubmed

Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression.

IRX5 IRX2

2.03e-05641236773339
Pubmed

Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development.

IRX5 IRX2

2.03e-05641211042145
Pubmed

Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast.

IRX5 IRX2

2.03e-05641210370142
Pubmed

The prepattern transcription factor Irx3 directs nephron segment identity.

IRX5 IRX2

2.84e-05741217875669
Pubmed

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.

BCL9L PYGO2

2.84e-05741230366904
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

COL4A3 COL12A1 COL13A1 COL19A1

3.21e-0515341425037231
Pubmed

Identification of a novel mouse Iroquois homeobox gene, Irx5, and chromosomal localisation of all members of the mouse Iroquois gene family.

IRX5 IRX2

3.78e-05841210822268
Pubmed

In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma.

IRX5 IRX2

3.78e-05841233206716
Pubmed

Genetic organization of complement receptor-related genes in the mouse.

CR1 CR2

3.78e-0584122564419
Pubmed

Sensitive nonradioactive detection of mRNA in tissue sections: novel application of the whole-mount in situ hybridization protocol.

IRX5 IRX2

3.78e-05841211118473
Pubmed

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.

BCL9L PYGO2

3.78e-05841228296634
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

ADAMTS17 COL12A1 COL13A1 SFTPA2

4.52e-0516741422159717
Pubmed

The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice.

IRX5 IRX2

4.86e-05941214585979
Pubmed

Gene and cluster-specific expression of the Iroquois family members during mouse development.

IRX5 IRX2

4.86e-05941211520674
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL4A3 COL22A1 COL12A1 SSPOP

5.42e-0517541428071719
Pubmed

Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells.

CR1 CR2

7.41e-05114121543915
Pubmed

Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart.

IRX5 IRX2

7.41e-051141210926765
Pubmed

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.

DMRTC2 IRX5 EN2 IRX2

7.61e-0519141424146773
Pubmed

Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.

CR1 CR2

1.05e-041341216002709
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

COL4A3 COL12A1 COL13A1 COL19A1

1.10e-0421041416537572
Pubmed

A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.

BCL9L PYGO2

1.22e-041441228174279
Pubmed

A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.

COL13A1 BSN

1.61e-041641225082827
Pubmed

Wnt/β-catenin promotes gastric fundus specification in mice and humans.

IRX5 IRX2

2.05e-041841228052057
Pubmed

The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development.

IRX5 IRX2

2.29e-041941216182275
Pubmed

Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.

CSRNP1 IRX5

2.29e-041941224564958
Pubmed

Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study.

BSN PHOX2B

2.54e-042041220846217
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

SIX5 IRX5 EN2 IRX2

2.60e-0426341420932939
Pubmed

Constitutive expression of TNF-alpha and -beta genes in mouse embryo: roles of cytokines as regulator and effector on development.

CR1 CR2

2.81e-04214128138038
Pubmed

Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.

PHOX2B EN2

2.81e-042141211500373
Pubmed

Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation.

COL4A3 SFTPA2

3.09e-042241221513708
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

COL4A3 COLEC11 C8B CR1 CR2 FCN2

3.85e-0482441620237496
Pubmed

Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression.

IRX5 IRX2

4.33e-042641211238910
Pubmed

Molecular architecture of the developing mouse brain.

IRX5 PHOX2B EN2

5.13e-0413241334321664
Pubmed

Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5.

COL19A1 IRX2

5.39e-042941229543863
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

COL4A3 COL12A1 COL13A1

5.47e-0413541328675934
Pubmed

Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning.

IRX5 IRX2

5.78e-043041226450968
Pubmed

Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.

SIX5 COLEC11 COL13A1

6.34e-0414241319851296
Pubmed

A census of human transcription factors: function, expression and evolution.

DMRTC2 SIX5 IRX5 PHOX2B EN2 IRX2

6.42e-0490841619274049
Pubmed

Association of genetic variants with hemorrhagic stroke in Japanese individuals.

SIX5 COLEC11 COL13A1

6.47e-0414341320198315
Pubmed

FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex.

COL12A1 COL13A1

9.77e-043941233580754
InteractionCOLGALT2 interactions

COLEC11 C1QTNF2 COL12A1 COL13A1

7.56e-0667384int:COLGALT2
Cytoband6q12-q13

COL12A1 COL19A1

7.77e-0654126q12-q13
Cytoband1q32

CR1 CR2

8.91e-04494121q32
GeneFamilyCollagens

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

8.02e-0946285490
GeneFamilyComplement system|Sushi domain containing

C8B CR1 CR2

2.30e-0536283492
GeneFamilyCollectins

COLEC11 SFTPA2

1.03e-0410282491
GeneFamilyTALE class homeoboxes and pseudogenes

IRX5 IRX2

7.35e-0426282526
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

COLEC11 SFTPA2

1.83e-03412821298
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CR1 CR2

3.50e-03572821179
CoexpressionNABA_COLLAGENS

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

6.70e-0943415MM17060
CoexpressionNABA_COLLAGENS

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

7.55e-0944415M3005
CoexpressionNABA_MATRISOME

ADAMTS17 COL4A3 COLEC11 C1QTNF2 COL22A1 GLDN COL12A1 COL13A1 SFTPA2 COL19A1 SSPOP FCN2

2.76e-0810084112MM17056
CoexpressionNABA_MATRISOME

ADAMTS17 COL4A3 COLEC11 C1QTNF2 COL22A1 GLDN COL12A1 COL13A1 SFTPA2 COL19A1 SSPOP FCN2

3.35e-0810264112M5889
CoexpressionNABA_CORE_MATRISOME

COL4A3 COL22A1 GLDN COL12A1 COL13A1 COL19A1 SSPOP

1.90e-07270417MM17057
CoexpressionNABA_CORE_MATRISOME

COL4A3 COL22A1 GLDN COL12A1 COL13A1 COL19A1 SSPOP

2.15e-07275417M5884
CoexpressionSHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_DN

IRX5 IRX2

4.99e-057412M19757
CoexpressionNABA_ECM_AFFILIATED

COLEC11 C1QTNF2 SFTPA2 FCN2

1.08e-04158414MM17063
CoexpressionXIE_TRASTUZUMAB_CARDIOTOXICITY_MMU_MIR_483_5P_GENES

BCL9L PYGO2

1.30e-0411412MM17503
CoexpressionNABA_ECM_AFFILIATED

COLEC11 C1QTNF2 SFTPA2 FCN2

1.43e-04170414M5880
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL22A1 GLDN COL12A1 COL13A1 SPOCD1

6.18e-0718340527a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL4A3 TNRC6B COL19A1 CR1 CR2

8.24e-07194405ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

TRABD2B GLDN COL12A1 COL13A1

9.62e-06149404651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS17 IRX5 SFTPA2 IRX2

1.54e-05168404e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS17 IRX5 SFTPA2 IRX2

1.54e-0516840416b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL22A1 COL12A1 COL19A1 SSPOP

2.21e-05184404ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL22A1 COL12A1 COL19A1 SSPOP

2.21e-051844042cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL22A1 COL12A1 COL19A1 SSPOP

2.21e-051844042b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell10x5'-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

COL4A3 COL19A1 CR1 CR2

2.30e-05186404a5c0bd4f6a7542f67d478dcdc0645ae6d927a395
ToppCelldroplet-Liver-Npc-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 CDAN1 SIX5 COL13A1

2.30e-0518640475258d88e23112fd1f0f7c71ef0366abb400d33e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TRABD2B GLDN COL12A1 IRX5

2.35e-05187404f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TRABD2B GLDN COL12A1 IRX5

2.35e-0518740402e7246ef5ad41773d14426254e139b156d45c1d
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TRABD2B GLDN COL12A1 IRX5

2.35e-0518740408c73d125e0638c9e9878165bba2442c266c8a48
ToppCellPericytes-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COLEC11 TRABD2B COL12A1 COL13A1

2.40e-05188404f16ff998393bf1954bbf10caab15173bdb104ac1
ToppCell10x5'-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

COL4A3 COL19A1 CR1 CR2

2.40e-05188404ab1384e6f71053946368502282aeebf1ba92d33e
ToppCellIPF-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

COLEC11 TRABD2B COL22A1 SPOCD1

2.45e-051894044178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

C1QTNF2 COL12A1 COL19A1 IRX2

2.45e-05189404c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCellSmart-seq2-spleen_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL4A3 CSRNP1 CR1 CR2

2.45e-05189404b0244a9d1b5c8ad4708750b691184f3491b13900
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COLEC11 TTC9 IRX5 WBP1L

2.45e-051894041137583e21d874c201c20581ba1995e2bfa3de59
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COLEC11 TTC9 IRX5 WBP1L

2.50e-051904047068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

C1QTNF2 COL22A1 COL12A1 COL13A1

2.50e-05190404cf463b2f227f3cc7d3fd296c810c0cbe51cbee72
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS17 COLEC11 IRX5 WBP1L

2.60e-051924040b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCellMesenchymal_cells-Ng2+_MSCs|World / Lineage and Cell class

COL22A1 COL12A1 COL13A1 IRX5

2.60e-051924040703b8ec6960ff975ee5a2737054db67cab016b5
ToppCellB_cells-Memory_B_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

COL4A3 COL19A1 CR1 CR2

2.60e-05192404eef591095921ede098f41a2b81897b18915bb753
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COLEC11 TTC9 IRX5 WBP1L

2.71e-05194404c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCellBronchial_Biopsy-Immune-Luminal_Macrophages|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

GLDN C8B CR1 SPOCD1

2.77e-051954046800c17026ec6c56132bf4664b8fcd74d7836579
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COLEC11 TTC9 IRX5 WBP1L

2.77e-05195404df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCelltumor_Lung-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

GLDN C8B SPOCD1 PRR13

2.77e-051954043133591a289c06396cf4705d6a861369e145ac54
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS17 COLEC11 IRX5 WBP1L

2.82e-05196404e386526332138e636aef2542c11316347a45689c
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A3 COL19A1 CR1 CR2

2.82e-05196404c2e17f3b2217f20bd7f28a1db4aa7d9a95c52a9c
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL22A1 COL12A1 COL13A1 SPOCD1

2.88e-051974042ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B|lymph-node_spleen / Manually curated celltypes from each tissue

COL4A3 COL19A1 CR1 CR2

2.88e-051974049837bd2cc28b79147fb5d1997631ef953fd020e4
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL4A3 COL19A1 CR1 CR2

2.88e-05197404fa3cc33c975648172feabb485c3bdd087f1f8ea7
ToppCellLPS_anti-TNF-Epithelial_alveolar|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL4A3 IRX5 SFTPA2 IRX2

2.94e-0519840453e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF2 COL22A1 COL12A1 COL13A1

2.94e-05198404524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B|lymph-node_spleen / Manually curated celltypes from each tissue

COL4A3 COL19A1 CR1 CR2

2.94e-051984041780fa1725a321041094e8c4430673c0a4f3d407
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL4A3 IRX5 SFTPA2 IRX2

3.05e-05200404c89f3cb36bb14c476d6a392bfd3ded1c8feecfeb
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Igsf8_(Ctps)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GARIN5B IRX5 SSPOP

4.91e-0579403eddad041c0bc6952d9c68a36bdd78f6d661f0e58
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Igsf8_(Ctps)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GARIN5B IRX5 SSPOP

4.91e-05794034c9c3051cb8a9c39c6df20e3fe37242db4b44280
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL4A3 TRABD2B COL12A1

7.01e-0589403eda156a61e7d14087cfdae5e733d6862834fb0e5
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

1.05e-041024030bbc6344d0baee47326a16a89773bb5c68a7b040
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

1.05e-0410240311fbdb428824023603e9d4ee41e957ba84e7c29e
ToppCellSubstantia_nigra|World / BrainAtlas - Mouse McCarroll V32

IRX5 EN2 IRX2

1.50e-0411540318174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

1.96e-04126403f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

1.96e-04126403fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

1.96e-041264031ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

1.96e-041264032de551d7a8765afec1da8852727c79fec90f45f8
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP|Entopeduncular / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

1.96e-041264033d507f829882d043f633db2612b76936e2042445
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

2.25e-04132403560e836764ed7806fb18282dfebe434d30112a9a
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

2.25e-04132403893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Striatum / BrainAtlas - Mouse McCarroll V32

COLEC11 TRABD2B GLDN

2.35e-04134403a3547a68012d879d4dfe80394eace70808722e43
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Striatum / BrainAtlas - Mouse McCarroll V32

COLEC11 TRABD2B GLDN

2.35e-041344039458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SIX5 COL22A1 IRX5

2.41e-04135403c4d3c9eba2a85ac40fea5ecfcc2b442a472323d0
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-13|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COLEC11 COL19A1 CR2

2.91e-04144403b2a9f3b5dd46d27689467f4a5fd717cd5827821f
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A3 COL19A1 MYLK3

3.28e-041504034bdcdce40f54580c7a4e1416b468e657ba8874fc
ToppCellTransplant_Alveoli_and_parenchyma-Immune-B_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A3 COL19A1 CR2

3.41e-0415240366f9190de155251a63a7a669374f342a75d22ea0
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Thalamus / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

3.47e-04153403e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

3.47e-04153403b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP|Thalamus / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

3.47e-041534032513edfae62a44e51d3556675a096723194c966c
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL4A3 COL19A1 CR2

3.61e-04155403d336559092563b0d7776eef873f1d2759aca45f7
ToppCelldroplet-Liver-Npc-21m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRABD2B IRX5 IRX2

3.61e-04155403d883a3869cf893d62741f26f641ed3923aba03f9
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COL22A1 GLDN COL13A1

3.68e-04156403fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TTC9 COL22A1 BSN

3.75e-04157403f6210be2362d833c6d869ff921188bfc85dda11d
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TTC9 COL22A1 BSN

3.75e-0415740343a6b423fd70479822a564ff4225a1e4951ae5ed
ToppCellStriatum-Neuronal-Inhibitory|Striatum / BrainAtlas - Mouse McCarroll V32

ADAMTS17 COL19A1 CR2

3.75e-04157403c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF2 COL12A1 IRX5

3.82e-04158403f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF2 COL12A1 IRX5

3.82e-041584038c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

C1QTNF2 COL12A1 COL13A1

3.89e-04159403cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

3.89e-0415940392049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

IRX5 SFTPA2 IRX2

3.96e-04160403b81d218c20fe37921cf3c6c7db2da3bfd367230a
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF2 IRX5 COL19A1

3.96e-041604038590281165eab6514a9f6a022b900d4c222c1044
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

IRX5 SFTPA2 IRX2

3.96e-04160403ac5d573c135d66d6adddd42dfddd9d3e01532172
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 COL12A1 ZNF446

4.11e-04162403ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellnormal_Lung-Epithelial_cells-Undetermined|normal_Lung / Location, Cell class and cell subclass

GLDN SFTPA2 IRX2

4.25e-04164403fa2dae15b38cb8f9642dbf00549beec8ee19e9bb
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

4.33e-04165403570483b43ccb5831feec9337b4664814431d40b1
ToppCellfacs-Kidney-nan-24m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIX5 COLEC11 C1QTNF2

4.33e-04165403c746bb22ef52d7f7fa6ee9c37ae6bbe0ccce718e
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL22A1 COL12A1 COL13A1

4.33e-041654032026a9a07f4d314cc05c167e491312b373468e46
ToppCellfacs-Kidney-nan-24m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIX5 COLEC11 C1QTNF2

4.33e-041654034cdd80580d5638fd649280ba3893251c2f898f3f
ToppCellCF-Myeloid-Alveolar_Macrophage|Myeloid / Disease state, Lineage and Cell class

GLDN C8B SPOCD1

4.33e-0416540369ad83f2e4da62acfdf0a5a299d8444932a61160
ToppCellwk_20-22-Epithelial-Airway_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL4A3 SFTPA2 IRX2

4.41e-04166403fcd0bd70b553789092249806ace324b77bd10481
ToppCellwk_20-22-Epithelial-Airway_epithelial_progenitor-epi-stalk_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL4A3 SFTPA2 IRX2

4.41e-04166403b60954e5625743657d0fd9264b738b46e72fd8a6
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GLDN BSN EN2

4.41e-041664036a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 COL13A1 IRX5

4.49e-04167403805129f887078340b260aa136b0ba19f2bd6ea03
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 COL13A1 IRX5

4.49e-0416740331cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 COL13A1 IRX5

4.49e-041674033acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS17 COLEC11 TTC9

4.56e-0416840306dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 MYLK3 CR1

4.56e-04168403fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 MYLK3 CR1

4.56e-04168403e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS17 COLEC11 TTC9

4.56e-041684031002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A3 COL19A1 CR2

4.64e-04169403307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 COL12A1 IRX2

4.64e-04169403cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 MYLK3 CR1

4.72e-0417040360bbd738c12e64e483485586c30057304884f5a6
ToppCellfacs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSRNP1 C1QTNF2 MYLK3

4.72e-0417040312203d4410f38cc933d9f160b5fb76828df94119
ToppCellfacs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSRNP1 C1QTNF2 MYLK3

4.72e-04170403f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCelldroplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF2 GLDN COL13A1

4.72e-0417040310e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 MYLK3 CR1

4.89e-04172403381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 IRX5 IRX2

4.97e-0417340345808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS17 GLDN COL19A1

4.97e-041734032e35bf2b5534a289d93a09faae660f665c131062
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 C1QTNF2 TRABD2B

4.97e-0417340351328a60ffaf34fa0f7df6084d348b5efc9917f5
ToppCellGlobus_pallidus-Endothelial-MURAL|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 C1QTNF2 TRABD2B

4.97e-04173403b77cd5dbda3a206922f20224f4e10a3bf712f7db
DrugAC1LAKND

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

8.83e-0862415CID000470146
DrugBAPN

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.75e-0771415CID000001647
Drughalofuginone lactate

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

4.34e-0785415CID000062891
DrugGK-101

COL4A3 COL22A1 COL12A1 COL13A1

5.11e-0736414CID000161853
Drug4-hydroxyproline

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

6.11e-0791415CID000000825
Drugticlopidine

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.13e-06103415CID000005472
DrugMadecassol

COL4A3 COL22A1 COL12A1 COL13A1

1.40e-0646414CID000108062
Drughydroxylysine

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.50e-06109415CID000001029
DrugTranilast sodium

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.95e-06115415CID000005527
Drugd-indobufen

COL4A3 COL22A1 COL12A1 COL13A1

1.96e-0650414CID000044562
Drugridogrel

COL4A3 COL22A1 COL12A1 COL13A1

2.30e-0652414CID005362391
DrugNSC49633

COL4A3 COL22A1 COL12A1 COL13A1

2.49e-0653414CID000023340
DrugSelara

COL4A3 COL22A1 COL12A1 COL13A1 IRX2

2.94e-06125415CID000150310
Drugpirfenidone

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

4.78e-06138415CID000040632
DrugDL-penicillamine

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

4.95e-06139415CID000004727
DrugPCR 4099

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

4.95e-06139415CID000002806
Drugcolchine

COL4A3 CDAN1 COL22A1 COL12A1 COL13A1 COL19A1 BSN

4.96e-06383417CID000002833
Drugmalotilate

COL4A3 COL22A1 COL12A1 COL13A1

8.06e-0671414CID000004006
DrugAC1NMZ1B

COL4A3 COL22A1 COL12A1 COL13A1

1.00e-0575414CID005034185
Drugstrontium ranelate

COL4A3 COL22A1 COL12A1 COL13A1

1.11e-0577414CID006918182
Drugkhellin

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.36e-05171415CID000003828
DrugAC1L1DD6

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.69e-05179415CID000002299
Drugfoscarnet

COL4A3 COL22A1 COL12A1 COL13A1 BSN

2.25e-05190415CID000003414
DrugAC1L1C2F

COL4A3 COL22A1 COL12A1 COL13A1

4.55e-05110414CID000001711
DrugPPACK

COL4A3 COL22A1 COL12A1 COL13A1

5.06e-05113414CID003036757
DrugAC1L9732

COL4A3 COL22A1 COL12A1 COL13A1

5.23e-05114414CID000439300
DrugAC1Q6PCP

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

5.61e-05230415CID000005267
DrugDMSe

COL4A3 COL22A1 COL12A1 COL13A1

9.26e-05132414CID000020796
Drughyaluronan

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.06e-04263415CID000024759
Drugcandesartan cilexetil

COL4A3 COL22A1 COL12A1 COL13A1

1.33e-04145414CID000002540
Drugsilibinin

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

1.54e-04285415CID000005213
DrugL-lysyl-L-lysyl-L-lysine

COL4A3 COL22A1 COL12A1 COL13A1

2.04e-04162414CID000072363
DrugAC1L18QD

COL4A3 COL22A1 COL12A1 COL13A1 COL19A1

2.83e-04325415CID000000213
DrugL-3,4-dehydroproline

COL22A1 COL13A1 COL19A1

3.09e-0473413CID000094284
Drug12(S)-hydroxyeicosatetraenoic acid

COL4A3 COL22A1 COL12A1 COL13A1

3.66e-04189414CID000001413
DrugCP-320650-01 [172079-28-6]; Up 200; 1uM; MCF7; HT_HG-U133A

COL4A3 TTC9 CR1 EN2

4.12e-041954144382_UP
DiseaseLung diseases

IRX5 PHOX2B IRX2

1.64e-0478403C0024115
Diseasemannan-binding lectin serine protease 1 measurement

COLEC11 FCN2

1.86e-0415402EFO_0008223

Protein segments in the cluster

PeptideGeneStartEntry
GCAGSPGLPGSPGPP

COL4A3

421

Q01955
QPGPPGEQGPPGRCI

COL4A3

796

Q01955
CLTGPSGPPGPPGAG

GLDN

136

Q6ZMI3
GGPCPPPTFPGCQGF

CDAN1

556

Q8IWY9
DNPPPGPGGTHCPGA

ADAMTS17

571

Q8TE56
GGGNEGSPCPPCPGP

IRX5

351

P78411
CPTHPGLPGPGFQPG

CSRNP1

371

Q96S65
PAGGPLPPGGDTCPQ

BSN

3516

Q9UPA5
CSLPGPQGPPGPPGA

C1QTNF2

36

Q9BXJ5
GGGLCAGPSPPPPRC

FBXO31

51

Q5XUX0
TPAPPGAPGGPACLG

IRF2BPL

286

Q9H1B7
CPGGGSPPGAALPHP

OR2W5P

201

A6NFC9
GTRLTPGPGPQCPGP

MYLK3

301

Q32MK0
PNIGCPGGSNPAHPP

PRR13

16

Q9NZ81
KQPSLGPGCGPPGLP

IRX2

341

Q9BZI1
GPGCGPPGLPAAAAP

IRX2

346

Q9BZI1
GGSGPQPPPGLVYPC

PYGO2

316

Q9BRQ0
CPPPPKTPNGNHTGG

CR2

851

P20023
PCGPPAPAGGRGFQP

DMRTC2

326

Q8IXT2
PVGPPAPGLPFCCGG

CR1

11

P17927
CTQDSVGPPGPPGPA

COL12A1

2741

Q99715
PGPQGPPGPSGRCNP

COL19A1

1111

Q14993
PGPNGAPGEPQPCLT

FCN2

86

Q15485
PGGPDSLNAPCGPVP

BCL9L

1206

Q86UU0
GPPGPNGEPGLPCEC

COLEC11

101

Q9BWP8
PGPPGPPGQCDPSQC

COL22A1

1596

Q8NFW1
QNPPCAPGAGGPLPA

EN2

131

P19622
GCNCPPGPPGPTGRP

COL13A1

116

Q5TAT6
PPPQNGGSPCSGPAS

C8B

571

P07358
AGPRPQQASPPPCGG

OTUD5

91

Q96G74
QQASPPPCGGPGGPG

OTUD5

96

Q96G74
CPNNPPVPGAPPGQG

DROSHA

126

Q9NRR4
PPPKNGGAPCPGASQ

SSPOP

2586

A2VEC9
LTGGGGAPPPQPSPQ

SIX5

361

Q8N196
GPPGETPCPPGNNGL

SFTPA2

61

Q8IWL1
TPCPPGNNGLPGAPG

SFTPA2

66

Q8IWL1
APDSCQPGPGPSPGL

ZNF414

71

Q96IQ9
PQPPDGGQCRPPGSQ

TRABD2B

21

A6NFA1
QPGSPCGPVGFPVPS

SPOCD1

296

Q6ZMY3
SEGPPGCPEAQPPQG

ZNF446

271

Q9NWS9
GCPEAQPPQGPGPAA

ZNF446

276

Q9NWS9
GGPGPNPNPTPSCGA

PHOX2B

196

Q99453
QLLPPQCGPAGGSPP

WBP1L

131

Q9NX94
GAGPPPCTAPGANPN

TNRC6B

121

Q9UPQ9
EGQRPPPPLCVPGGG

TTC9

21

Q92623
PPPLCVPGGGGGAPA

TTC9

26

Q92623
GPMGSHQGPGPPPCQ

GARIN5B

386

Q8N5Q1
HQGPGPPPCQKAPSG

GARIN5B

391

Q8N5Q1