Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesslymphocyte anergy

ITCH RUNX1 CBLB

3.55e-05101403GO:0002249
GeneOntologyBiologicalProcessregulation of T cell anergy

ITCH RUNX1 CBLB

3.55e-05101403GO:0002667
GeneOntologyBiologicalProcessT cell anergy

ITCH RUNX1 CBLB

3.55e-05101403GO:0002870
GeneOntologyBiologicalProcessregulation of lymphocyte anergy

ITCH RUNX1 CBLB

3.55e-05101403GO:0002911
DomainEGF-like_dom

CLEC18A EREG CLEC18B CLEC18C LAMB2 TECTA VWDE DLL3 NOTCH2 NOTCH3 OTOG

1.71e-0624913311IPR000742
DomainEGF

CLEC18A EREG CLEC18B CLEC18C LAMB2 TECTA VWDE DLL3 NOTCH2 NOTCH3

7.17e-0623513310SM00181
Domain-

ADAMTSL1 IGFN1 MXRA5 TIMD4 VSIG1 SIRPA PLXND1 SEMA4G TGM5 JAM2 CEACAM19 CD58 ROBO1 IL6R PLXNB1 IL9R

2.01e-05663133162.60.40.10
DomainIg-like_fold

ADAMTSL1 IGFN1 MXRA5 TIMD4 VSIG1 SIRPA PLXND1 SEMA4G TGM5 JAM2 CEACAM19 CD58 ROBO1 IL6R PLXNB1 IL9R

4.28e-0570613316IPR013783
DomainEGF_3

CLEC18A EREG CLEC18B CLEC18C VWDE DLL3 NOTCH2 NOTCH3 OTOG

4.77e-052351339PS50026
DomainZU5

ANK1 ANK2 SH3BP4

7.41e-05121333PF00791
DomainZU5_dom

ANK1 ANK2 SH3BP4

7.41e-05121333IPR000906
DomainEGF_1

CLEC18A EREG CLEC18B CLEC18C LAMB2 VWDE DLL3 NOTCH2 NOTCH3

8.94e-052551339PS00022
DomainEGF-like_CS

CLEC18A EREG CLEC18B CLEC18C LAMB2 VWDE DLL3 NOTCH2 NOTCH3

1.07e-042611339IPR013032
DomainEGF_2

CLEC18A EREG CLEC18B CLEC18C LAMB2 VWDE DLL3 NOTCH2 NOTCH3

1.20e-042651339PS01186
DomainDUF3454

NOTCH2 NOTCH3

1.50e-0431332PF11936
DomainDUF3454_notch

NOTCH2 NOTCH3

1.50e-0431332IPR024600
DomainDUF3454

NOTCH2 NOTCH3

1.50e-0431332SM01334
DomainCAP

CLEC18A CLEC18B CLEC18C

1.51e-04151333PF00188
DomainSCP

CLEC18A CLEC18B CLEC18C

1.51e-04151333SM00198
DomainAllrgn_V5/Tpx1

CLEC18A CLEC18B CLEC18C

1.51e-04151333IPR001283
Domain-

CLEC18A CLEC18B CLEC18C

1.51e-041513333.40.33.10
DomainCAP_domain

CLEC18A CLEC18B CLEC18C

1.51e-04151333IPR014044
DomainVWF_type-D

TECTA VWDE OTOG

1.85e-04161333IPR001846
DomainVWFD

TECTA VWDE OTOG

1.85e-04161333PS51233
DomainVWD

TECTA VWDE OTOG

1.85e-04161333SM00216
DomainVWD

TECTA VWDE OTOG

1.85e-04161333PF00094
DomainIG

ADAMTSL1 IGFN1 MXRA5 TIMD4 VSIG1 SIRPA SEMA4G JAM2 CD58 ROBO1 IL6R

2.15e-0442113311SM00409
DomainIg_sub

ADAMTSL1 IGFN1 MXRA5 TIMD4 VSIG1 SIRPA SEMA4G JAM2 CD58 ROBO1 IL6R

2.15e-0442113311IPR003599
DomainIg-like_dom

ADAMTSL1 IGFN1 MXRA5 TIMD4 VSIG1 SIRPA SEMA4G JAM2 CEACAM19 CD58 ROBO1 IL6R

2.56e-0450313312IPR007110
DomainSCA7

ATXN7L1 ATXN7

2.99e-0441332PF08313
DomainNotch

NOTCH2 NOTCH3

2.99e-0441332IPR008297
DomainNODP

NOTCH2 NOTCH3

2.99e-0441332PF07684
DomainNotch_NODP_dom

NOTCH2 NOTCH3

2.99e-0441332IPR011656
DomainSCA7_dom

ATXN7L1 ATXN7

2.99e-0441332IPR013243
DomainNotch_NOD_dom

NOTCH2 NOTCH3

2.99e-0441332IPR010660
DomainNOD

NOTCH2 NOTCH3

2.99e-0441332PF06816
DomainSCA7

ATXN7L1 ATXN7

2.99e-0441332PS51505
DomainNOD

NOTCH2 NOTCH3

2.99e-0441332SM01338
DomainNODP

NOTCH2 NOTCH3

2.99e-0441332SM01339
DomainVWC_out

CRIM1 TECTA OTOG

3.15e-04191333SM00215
DomainAWS

ASH1L NSD1

4.96e-0451332SM00570
DomainAWS

ASH1L NSD1

4.96e-0451332PS51215
DomainAWS_dom

ASH1L NSD1

4.96e-0451332IPR006560
DomainLNR

NOTCH2 NOTCH3

4.96e-0451332PS50258
DomainAnkyrin_rpt

ANK1 ANK2 BCORL1 ANKHD1 EXO1 TNKS NOTCH2 NOTCH3

5.84e-042621338IPR002110
Domain-

NBEA PLXND1 SEC31B SEMA4G TULP4 PLXNB1 WDR62 SEC13 FBXW7

6.42e-0433313392.130.10.10
DomainWD40/YVTN_repeat-like_dom

NBEA PLXND1 SEC31B SEMA4G TULP4 PLXNB1 WDR62 SEC13 FBXW7

6.70e-043351339IPR015943
DomainIG_LIKE

ADAMTSL1 IGFN1 MXRA5 TIMD4 VSIG1 SIRPA SEMA4G JAM2 CD58 ROBO1 IL6R

7.83e-0449113311PS50835
DomainhEGF

DLL3 NOTCH2 NOTCH3

1.02e-03281333PF12661
DomainNotch_dom

NOTCH2 NOTCH3

1.03e-0371332IPR000800
DomainNotch

NOTCH2 NOTCH3

1.03e-0371332PF00066
DomainNL

NOTCH2 NOTCH3

1.03e-0371332SM00004
DomainAnk

ANK1 ANK2 BCORL1 ANKHD1 TNKS NOTCH2 NOTCH3

1.25e-032281337PF00023
DomainSemap_dom

PLXND1 SEMA4G PLXNB1

1.37e-03311333IPR001627
DomainSEMA

PLXND1 SEMA4G PLXNB1

1.37e-03311333PS51004
DomainSema

PLXND1 SEMA4G PLXNB1

1.37e-03311333SM00630
DomainSema

PLXND1 SEMA4G PLXNB1

1.37e-03311333PF01403
DomainIGc2

ADAMTSL1 IGFN1 MXRA5 VSIG1 JAM2 ROBO1 IL6R

1.49e-032351337SM00408
DomainIg_sub2

ADAMTSL1 IGFN1 MXRA5 VSIG1 JAM2 ROBO1 IL6R

1.49e-032351337IPR003598
DomainPlexin_repeat

PLXND1 SEMA4G PLXNB1

1.51e-03321333IPR002165
DomainPSI

PLXND1 SEMA4G PLXNB1

1.51e-03321333PF01437
DomainPlexin_cytopl

PLXND1 PLXNB1

1.75e-0391332PF08337
DomainZU5

ANK1 ANK2

1.75e-0391332SM00218
DomainPlexin_cytoplasmic_RasGAP_dom

PLXND1 PLXNB1

1.75e-0391332IPR013548
DomainPlexin

PLXND1 PLXNB1

1.75e-0391332IPR031148
DomainEGF

EREG TECTA DLL3 NOTCH2 NOTCH3

2.08e-031261335PF00008
DomainANK

ANK1 ANK2 BCORL1 ANKHD1 TNKS NOTCH2 NOTCH3

2.16e-032511337SM00248
DomainZU5

ANK1 ANK2

2.18e-03101332PS51145
DomainAnk_3

ANK1 TNKS

2.18e-03101332PF13606
DomainANK_REPEAT

ANK1 ANK2 BCORL1 ANKHD1 TNKS NOTCH2 NOTCH3

2.26e-032531337PS50088
DomainAnkyrin_rpt-contain_dom

ANK1 ANK2 BCORL1 ANKHD1 TNKS NOTCH2 NOTCH3

2.31e-032541337IPR020683
DomainANK_REP_REGION

ANK1 ANK2 BCORL1 ANKHD1 TNKS NOTCH2 NOTCH3

2.31e-032541337PS50297
DomainSH3_9

SH3RF1 SORBS1 SH3BP4 MAP3K21

2.33e-03781334PF14604
DomainIntegrin_alpha

ITGAM ITGAX

2.65e-03111332PF00357
DomainVWFA

ITGAM ITGAX GTF2H2 CLCA2

2.80e-03821334PS50234
DomainIg_V-set

TIMD4 VSIG1 SIRPA JAM2 CEACAM19 ROBO1

3.04e-031991336IPR013106
DomainVWA

ITGAM ITGAX GTF2H2 CLCA2

3.05e-03841334SM00327
DomainSET

ASH1L NSD1 PRDM2

3.09e-03411333PF00856
DomainC8

TECTA OTOG

3.17e-03121332PF08742
DomainTIL

TECTA OTOG

3.17e-03121332PF01826
DomainVWF_dom

CRIM1 TECTA OTOG

3.31e-03421333IPR001007
DomainC-type_lectin_CS

CLEC18A CLEC18B CLEC18C

3.54e-03431333IPR018378
DomainUnchr_dom_Cys-rich

TECTA OTOG

3.73e-03131332IPR014853
DomainC8

TECTA OTOG

3.73e-03131332SM00832
DomainPSI

PLXND1 SEMA4G PLXNB1

3.78e-03441333IPR016201
DomainSET

ASH1L NSD1 PRDM2

4.29e-03461333SM00317
DomainPSI

PLXND1 SEMA4G PLXNB1

4.29e-03461333SM00423
DomainTIL_dom

TECTA OTOG

4.33e-03141332IPR002919
Domain-

ANK1 ANK2 RIPK2 NLRP5

4.40e-039313341.10.533.10
DomainAnk_2

ANK1 ANK2 BCORL1 TNKS NOTCH2 NOTCH3

4.43e-032151336PF12796
DomainGrowth_fac_rcpt_

CRIM1 LAMB2 DLL3 NOTCH2 NOTCH3

5.20e-031561335IPR009030
DomainSET_dom

ASH1L NSD1 PRDM2

5.42e-03501333IPR001214
DomainSET

ASH1L NSD1 PRDM2

5.42e-03501333PS50280
DomainDEATH-like_dom

ANK1 ANK2 RIPK2 NLRP5

5.49e-03991334IPR011029
DomainVWF_A

ITGAM ITGAX GTF2H2 CLCA2

5.49e-03991334IPR002035
DomainPost-SET_dom

ASH1L NSD1

5.66e-03161332IPR003616
DomainPostSET

ASH1L NSD1

5.66e-03161332SM00508
DomainIntegrin_alpha_C_CS

ITGAM ITGAX

5.66e-03161332IPR018184
DomainPOST_SET

ASH1L NSD1

5.66e-03161332PS50868
DomainSH3_1

SH3RF1 SORBS1 SLA SH3BP4 MAP3K21

6.41e-031641335PF00018
DomainIg_E-set

PLXND1 TGM5 ARHGDIA PLXNB1

6.53e-031041334IPR014756
PathwayPID_NOTCH_PATHWAY

ITCH DLL3 LNX1 NOTCH2 NOTCH3 FBXW7

6.01e-06591096M17
PathwayWP_NOTCH_SIGNALING_WP61

ITCH DLL3 NOTCH2 NOTCH3 FBXW7

1.06e-04611095M39540
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

DLL3 NOTCH2 NOTCH3

1.22e-04131093M47423
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HIVEP2 SH3RF1 LAT2 PPRC1 RNPEPL1 NSD1 LAMB2 TWNK CEP192 PLXND1 SRCAP ANKHD1 STK11IP FAAP100 SH3BP4 TBC1D16 TULP4 CABIN1 NOTCH2 MYBL2

4.27e-0811051462035748872
Pubmed

Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.

CLEC18A CLEC18B CLEC18C

7.25e-083146326170455
Pubmed

Association study of ITGAM, ITGAX, and CD58 autoimmune risk loci in systemic sclerosis: results from 2 large European Caucasian cohorts.

ITGAM ITGAX CD58

7.25e-083146321362770
Pubmed

The C-type lectin-like domain superfamily.

CLEC18A CLEC18B CLEC18C

7.25e-083146316336259
Pubmed

Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.

CLEC18A CLEC18B CLEC18C

7.25e-083146333603190
Pubmed

The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.

CLEC18A CLEC18B CLEC18C

2.89e-074146316709836
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ITCH HIVEP2 ANK2 CRIM1 KIF1A PPRC1 ASH1L NBEA SORBS1 RUNX1 SEC31B PAICS CEP63 DGLUCY ROBO1 YY1AP1 TNKS CABIN1 LNX1

2.00e-0612851461935914814
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ITCH HIVEP2 SH3RF1 RIPK2 SIK1 SORBS1 NUP62 CEP192 SH3BP4 CLMN EXO1 MAP3K21 NOTCH2 WDR62 OTOG

3.74e-068611461536931259
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

DLL3 NOTCH2 NOTCH3

5.98e-069146311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

DLL3 NOTCH2 NOTCH3

5.98e-069146316245338
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

DLL3 NOTCH2 NOTCH3

8.51e-0610146323665443
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

IL6R NOTCH2 NOTCH3

8.51e-0610146333915108
Pubmed

Human transcription factor protein interaction networks.

TSHZ3 ATXN7L1 BCORL1 TWNK R3HDM2 PROSER1 NUP62 CEP192 SRCAP ANKHD1 PRDM2 SALL2 ATXN7 YY1AP1 CABIN1 HOMEZ SEC13 MYBL2 FBXW7

9.16e-0614291461935140242
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

DLL3 NOTCH2 NOTCH3

1.17e-0511146310878608
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

DLL3 NOTCH2 NOTCH3

1.55e-0512146315465494
Pubmed

Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression.

DLL3 NOTCH2 NOTCH3

1.55e-0512146314732396
Pubmed

Association of ITGAX and ITGAM gene polymorphisms with susceptibility to IgA nephropathy.

ITGAM ITGAX

1.75e-052146231227791
Pubmed

Leukocyte integrins.

ITGAM ITGAX

1.75e-05214628573344
Pubmed

NOTCH Single Nucleotide Polymorphisms in the Predisposition of Breast and Colorectal Cancers in Saudi Patients.

NOTCH2 NOTCH3

1.75e-052146234257585
Pubmed

BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1.

ITGAM ITGAX

1.75e-052146234283878
Pubmed

Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort.

PDE3A SLCO1C1

1.75e-052146227180831
Pubmed

Identification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functions.

GLIS3 GLIS1

1.75e-052146212042312
Pubmed

Effects of Notch2 and Notch3 on Cell Proliferation and Apoptosis of Trophoblast Cell Lines.

NOTCH2 NOTCH3

1.75e-052146226640406
Pubmed

Notch2 and Notch3 function together to regulate vascular smooth muscle development.

NOTCH2 NOTCH3

1.75e-052146222615991
Pubmed

Cbl-b and itch: key regulators of peripheral T-cell tolerance.

ITCH CBLB

1.75e-052146220395198
Pubmed

GWAS replication study confirms the association of PDE3A-SLCO1C1 with anti-TNF therapy response in rheumatoid arthritis.

PDE3A SLCO1C1

1.75e-052146223651021
Pubmed

Structural basis for recognition of the third SH3 domain of full-length R85 (R85FL)/ponsin by ataxin-7.

SORBS1 ATXN7

1.75e-052146223892081
Pubmed

Ataxin-7 interacts with a Cbl-associated protein that it recruits into neuronal intranuclear inclusions.

SORBS1 ATXN7

1.75e-052146211371513
Pubmed

Deletion of the complement phagocytic receptors CR3 and CR4 does not alter susceptibility to experimental cerebral malaria.

ITGAM ITGAX

1.75e-052146222882618
Pubmed

Integrin CD11c contributes to monocyte adhesion with CD11b in a differential manner and requires Src family kinase activity.

ITGAM ITGAX

1.75e-052146218541300
Pubmed

Association of the PDE3A-SLCO1C1 locus with the response to anti-TNF agents in psoriasis.

PDE3A SLCO1C1

1.75e-052146225403996
Pubmed

Expression of notch family proteins in placentas from patients with early-onset severe preeclampsia.

NOTCH2 NOTCH3

1.75e-052146224336671
Pubmed

CD11c- and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain.

ITGAM ITGAX

1.75e-052146216051744
Pubmed

Distinct fetal Ank-1 and Ank-2 related proteins and mRNAs in normal and nb/nb mice.

ANK1 ANK2

1.75e-05214628471772
Pubmed

CD11c(+)/CD11b(+) cells are critical for organic dust-elicited murine lung inflammation.

ITGAM ITGAX

1.75e-052146222822029
Pubmed

A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.

IL6R NOTCH2 NOTCH3

2.01e-0513146332929274
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

DLL3 NOTCH2 NOTCH3

2.01e-0513146311578869
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

SH3RF1 RUNDC3B R3HDM2 SORBS1 CEP192 CLIP1 EXO1 MAP3K21 NOTCH2 WDR62

2.04e-054461461024255178
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

DLL3 NOTCH2 NOTCH3

2.55e-0514146314757642
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

DLL3 NOTCH2 NOTCH3

3.18e-0515146312971992
Pubmed

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

NOTCH2 NOTCH3 FBXW7

3.18e-0515146314672936
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

DLL3 NOTCH2 NOTCH3

3.18e-0515146316914494
Pubmed

The notch pathway positively regulates programmed cell death during erythroid differentiation.

RUNX1 DLL3 NOTCH2 NOTCH3

3.55e-0544146417476283
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

DLL3 NOTCH2 NOTCH3

3.90e-0516146312617809
Pubmed

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.

DLL3 NOTCH2 NOTCH3

3.90e-0516146311739954
Pubmed

A human MAP kinase interactome.

HIVEP2 SH3RF1 LAMB2 SORBS1 CBLB SH3BP4 ARHGDIA ROBO1 YY1AP1 MAP3K21

4.22e-054861461020936779
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

DLL3 NOTCH2 NOTCH3

4.72e-0517146318694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

DLL3 NOTCH2 NOTCH3

4.72e-0517146315821257
Pubmed

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.

DLL3 NOTCH2 NOTCH3

4.72e-0517146339315665
Pubmed

Regulation of immune responses by E3 ubiquitin-protein ligases.

ITCH CBLB

5.24e-053146211826757
Pubmed

Aggravated Lyme carditis in CD11a-/- and CD11c-/- mice.

ITGAM ITGAX

5.24e-053146216239568
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH2 NOTCH3

5.24e-05314628645602
Pubmed

Chromosomal location of the genes encoding the leukocyte adhesion receptors LFA-1, Mac-1 and p150,95. Identification of a gene cluster involved in cell adhesion.

ITGAM ITGAX

5.24e-05314623284962
Pubmed

The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies.

ITGAM ITGAX

5.24e-05314622185332
Pubmed

Socioeconomic status moderates associations between CNS serotonin and expression of beta2-integrins CD11b and CD11c.

ITGAM ITGAX

5.24e-053146219800635
Pubmed

EGFL7 participates in regulating biological behavior of growth hormone-secreting pituitary adenomas via Notch2/DLL3 signaling pathway.

DLL3 NOTCH2

5.24e-053146228705113
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH2 NOTCH3

5.24e-053146227697639
Pubmed

Surfactant protein D regulates the cell surface expression of alveolar macrophage beta(2)-integrins.

ITGAM ITGAX

5.24e-053146217056703
Pubmed

Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.

ANK1 ANK2

5.24e-053146221177872
Pubmed

Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport.

SEC31B SEC13

5.24e-053146210788476
Pubmed

Haplotype analysis of the CD11 gene cluster in patients with chronic Helicobacter pylori infection and gastric ulcer disease.

ITGAM ITGAX

5.24e-053146215730520
Pubmed

Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).

ITGAM ITGAX

5.24e-053146219129174
Pubmed

Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1).

GLIS3 GLIS1

5.24e-053146218263616
Pubmed

Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer.

NOTCH3 MYBL2

5.24e-053146236854682
Pubmed

Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in pre-eclampsia: a genetic and functional study.

ITGAM ITGAX

5.24e-053146233539617
Pubmed

Multinucleated Giant Cells Are Specialized for Complement-Mediated Phagocytosis and Large Target Destruction.

ITGAM ITGAX

5.24e-053146226628365
Pubmed

Induction of murine macrophage TNF-alpha synthesis by Mycobacterium avium is modulated through complement-dependent interaction via complement receptors 3 and 4 in relation to M. avium glycopeptidolipid.

ITGAM ITGAX

5.24e-053146215899409
Pubmed

MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growth.

ANK1 ANK2

5.24e-053146216597699
Pubmed

The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells.

LAT2 RUNX1

5.24e-053146224456692
Pubmed

Activation-Induced TIM-4 Expression Identifies Differential Responsiveness of Intestinal CD103+ CD11b+ Dendritic Cells to a Mucosal Adjuvant.

TIMD4 ITGAM

5.24e-053146227379516
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH2 NOTCH3

5.24e-05314627615640
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH2 NOTCH3

5.24e-05314627918097
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH2 NOTCH3

5.24e-053146221471519
Pubmed

Y chromosomal noncoding RNAs regulate autosomal gene expression via piRNAs in mouse testis.

PMEL CABIN1

5.24e-053146234503492
Pubmed

Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.

ANK1 ANK2

5.24e-053146212527750
Pubmed

GLIS3, a novel member of the GLIS subfamily of Krüppel-like zinc finger proteins with repressor and activation functions.

GLIS3 GLIS1

5.24e-053146214500813
Pubmed

CD11a regulates effector CD8 T cell differentiation and central memory development in response to infection with Listeria monocytogenes.

ITGAM ITGAX

5.24e-053146223357382
Pubmed

NF-κB p65 Overexpression Promotes Bladder Cancer Cell Migration via FBW7-Mediated Degradation of RhoGDIα Protein.

ARHGDIA FBXW7

5.24e-053146228772241
Pubmed

Gene of the month: GLIS1-3.

GLIS3 GLIS1

5.24e-053146232699115
Pubmed

Fbw7γ-mediated degradation of KLF13 prevents RANTES expression in resting human but not murine T lymphocytes.

CCL5 FBXW7

5.24e-053146222797700
Pubmed

Human ankyrins and their contribution to disease biology: An update.

ANK1 ANK2

5.24e-053146233410423
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH2 NOTCH3

5.24e-053146229767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH2 NOTCH3

5.24e-05314627698746
Pubmed

[Participation of beta2-integrins CD11b/CD18 and CD11c/CD18 in adhesion and migration of cells on fibrinogen].

ITGAM ITGAX

5.24e-053146221874872
Pubmed

T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases.

NOTCH2 NOTCH3

5.24e-053146227717083
Pubmed

Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells.

NOTCH2 NOTCH3

5.24e-053146225957400
Pubmed

CR3 (CD11b/CD18) and CR4 (CD11c/CD18) are involved in complement-independent antibody-mediated phagocytosis of Cryptococcus neoformans.

ITGAM ITGAX

5.24e-053146212121661
Pubmed

Infiltrating CD11b+CD11c+ cells have the potential to mediate inducible nitric oxide synthase-dependent cell death in mammary carcinomas of HER-2/neu transgenic mice.

ITGAM ITGAX

5.24e-053146219653277
Pubmed

Myofibrillogenesis Regulator-1 Regulates the Ubiquitin Lysosomal Pathway of Notch3 Intracellular Domain Through E3 Ubiquitin-Protein Ligase Itchy Homolog in the Metastasis of Non-Small Cell Lung Cancer.

ITCH NOTCH3

5.24e-053146238342606
Pubmed

ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.

ITCH RIPK2

5.24e-053146219592251
Pubmed

Structural basis of death domain signaling in the p75 neurotrophin receptor.

RIPK2 ARHGDIA

5.24e-053146226646181
Pubmed

Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.

ANK1 ANK2

5.24e-053146234289389
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

DLL3 NOTCH2 NOTCH3

5.65e-0518146315689374
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NBEA CEP192 MAGEE1 SEMA4G RAVER2

6.97e-05101146510997877
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

DLL3 NOTCH2 NOTCH3

9.12e-0521146328656980
Pubmed

Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+ CD11c+ cells.

ITGAM ITGAX

1.04e-044146221273385
Pubmed

Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP.

SRCAP NOTCH3

1.04e-044146221673954
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH2 NOTCH3

1.04e-044146224145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH2 NOTCH3

1.04e-044146220069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH2 NOTCH3

1.04e-044146219404845
InteractionPPP1R12B interactions

ANK1 ANK2 ANKHD1 TNKS NOTCH2 NOTCH3 DNPEP

4.57e-07681407int:PPP1R12B
CytobandEnsembl 112 genes in cytogenetic band chr10q24

PPRC1 TWNK SORBS1 SEC31B SEMA4G

3.62e-041891465chr10q24
Cytoband20q13.1

CDH22 MYBL2

4.45e-0410146220q13.1
GeneFamilyAnkyrin repeat domain containing

ANK1 ANK2 BCORL1 ANKHD1 TNKS NOTCH2 NOTCH3

3.06e-04242967403
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

ASH1L NSD1 PRDM2

7.70e-0434963487
GeneFamilyPlexins

PLXND1 PLXNB1

9.80e-049962683
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ADAMTSL1 IGFN1 MXRA5 JAM2 ROBO1

1.68e-03161965593
GeneFamilyAdenosine receptors|V-set domain containing

TIMD4 VSIG1 SIRPA JAM2 CEACAM19

1.77e-03163965590
GeneFamilyC-type lectin domain family

CLEC18A CLEC18B CLEC18C

1.99e-0347963494
GeneFamilyWD repeat domain containing

NBEA SEC31B TULP4 WDR62 SEC13 FBXW7

2.73e-03262966362
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

TSHZ3 HOMEZ

2.80e-0315962529
GeneFamilyCD molecules|Integrin alpha subunits

ITGAM ITGAX

4.04e-03189621160
GeneFamilyADAM metallopeptidase domain containing|CD molecules

SIRPA ITGAM ITGAX JAM2 CD58 IL6R IL9R

5.01e-03394967471
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ANK2 RUNDC3B FRMPD2 AMER3 PRR25 SLA STPG2 ROBO1

7.57e-0816514689795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DENND2A ADAMTSL1 EREG ANK2 GLIS3 LAMB2 CLCA2 DUOXA2

2.24e-071901468f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DENND2A ADAMTSL1 EREG ANK2 GLIS3 LAMB2 CLCA2 DUOXA2

2.24e-071901468a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DENND2A ADAMTSL1 EREG ANK2 GLIS3 LAMB2 CLCA2 DUOXA2

2.24e-07190146857c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

TSHZ3 HIVEP2 ANK2 KIF1A RUNDC3B NBEA SLA FBXW7

3.30e-072001468db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

TSHZ3 HIVEP2 ANK2 KIF1A RUNDC3B NBEA SLA FBXW7

3.30e-07200146830a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCelldroplet-Kidney-nan-3m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 SIRPA RUNX1 SLA ITGAX MAFB IL6R

1.29e-061661467961f93f7fb127f449cb1021f6ba73775dc666c53
ToppCelldroplet-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 SIRPA RUNX1 SLA ITGAX MAFB IL6R

1.29e-061661467fc71e871084299fb6f006c76f91e72026a290149
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIRPA RUNX1 ITGAM SLA ITGAX MAFB IL6R

1.35e-061671467991a93e1075d562b7391f0689b2f62c1351d48d1
ToppCellfacs-Kidney-nan-3m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIRPA RUNX1 ITGAM SLA ITGAX MAFB IL6R

1.35e-061671467f22d1471c785b30d096ec5cdc68974e850ed7de0
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIRPA RUNX1 ITGAM SLA ITGAX MAFB IL6R

1.35e-061671467934905aeaafbc215ec8f6a7903498b0e258b9220
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD2 CCDC175 CCDC168 PLXND1 CLMN CD58 FRMPD2B

1.52e-061701467985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCellfacs-Heart-LA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 SIRPA RUNX1 ITGAM SLA MAFB IL6R

1.77e-06174146730c083fe4711735e83dccfd00fcd746ae673d353
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 SIRPA RUNX1 ITGAM SLA MAFB IL6R

1.77e-06174146754166a0faf748cccb6406c2c268e1e6e21caf6d0
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 SIRPA RUNX1 ITGAM SLA MAFB IL6R

1.77e-06174146746d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 SIRPA RUNX1 ITGAM SLA MAFB IL6R

1.77e-0617414671802a52552256d1e25d8b328ba62dcfe41671900
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 SIRPA RUNX1 ITGAM SLA MAFB IL6R

1.77e-061741467dc8a238ec1d954bec0f8eb67c04a61734c96f5b5
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A PDE3A SORBS1 IRAG1 SLCO1C1 CLMN NOTCH3

1.77e-061741467015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellfacs-Heart-LV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 SIRPA RUNX1 ITGAM SLA MAFB IL6R

1.84e-0617514675d106ef542b97f97aeb19179e3f72963ead1e82a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 GLIS3 PLXND1 CBLB MEDAG ROBO1 NOTCH2

1.84e-061751467910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCelldroplet-Heart-HEART-1m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SIRPA RUNX1 ITGAM SLA MAFB

1.84e-06175146743b9cfd7c47d57244565c641e57f3256b5900804
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 GLIS3 PLXND1 CBLB MEDAG ROBO1 NOTCH2

1.84e-061751467f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SIRPA RUNX1 SLA MAFB IL6R

1.84e-061751467a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SIRPA RUNX1 ITGAM SLA MAFB

1.91e-0617614671df640f88667e2dad30e65279d6d33bba75024c1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 FRMPD2 GLIS3 CCDC175 CCDC168 CLMN FRMPD2B

1.91e-06176146740993c41c1017b53039a337174fc56632b278609
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A ADAMTSL1 SORBS1 IRAG1 CLMN MEDAG NOTCH3

2.14e-061791467111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 EREG ANK2 GLIS3 LAMB2 CLCA2 DUOXA2

2.66e-0618514673a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 EREG ANK2 GLIS3 LAMB2 CLCA2 DUOXA2

2.66e-061851467224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPBWR1 PDE3A ADAMTSL1 LAMB2 IRAG1 SLCO1C1 NOTCH3

2.96e-061881467d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND2A PDE3A CRIM1 IRAG1 SLCO1C1 CLMN NOTCH3

3.17e-0619014674eb92aef1ee868f4537483d19014d947b7684612
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A PDE3A CRIM1 SORBS1 IRAG1 CLMN NOTCH3

3.17e-061901467d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND2A PDE3A CRIM1 IRAG1 SLCO1C1 CLMN NOTCH3

3.17e-0619014677be4341e2909101d756f14031c21e705eb45e69a
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

DENND2A PDE3A CRIM1 SORBS1 IRAG1 CLMN NOTCH3

3.28e-061911467fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A PDE3A SORBS1 PAICS TGM5 MEDAG GLIS1

4.02e-0619714673332b9b5bf78f0203ebbd94257a36e9054d896c3
ToppCellNS-moderate-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EREG SIRPA PLXND1 ITGAM ITGAX MAFB IL6R

4.02e-061971467774a5053f43ac7d614c127ae7363d32a3a194f63
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSHZ3 PDE3A ANK2 SORBS1 CBLB JAM2 SLCO1C1

4.02e-061971467ee8f7def9d5af7b1e636830a4ea1da158d02f25a
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3A ADAMTSL1 ANK1 SORBS1 IRAG1 MEDAG NOTCH3

4.16e-061981467f261a37dd07976548b897af86df1d1a0dc069889
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A PDE3A ADAMTSL1 SORBS1 IRAG1 SLCO1C1 NOTCH3

4.16e-061981467bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A PDE3A IRAG1 SLCO1C1 CLMN MEDAG NOTCH3

4.16e-061981467882710bd6215e299257dd3df234292db9a2823ba
ToppCellPSB-critical-LOC-Myeloid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EREG LAT2 SIRPA ITGAM SLA ITGAX MAFB

4.16e-061981467437e2f84b64d99928aedbab7366ff0ec91e74038
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAT2 SIRPA ITGAM SLA ITGAX CD58 MAFB

4.30e-06199146722001aa733273e784051b7f750e07d99aaf7a225
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1|Neuronal / cells hierarchy compared to all cells using T-Statistic

FRMPD2 GLIS3 CCDC175 CCDC168 CLMN CD58 FRMPD2B

4.44e-062001467e0eccfdef3a1b4ffb47e7496764c7cf339618d39
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLEC18A PDE3A CLEC18B CLEC18C SORBS1 GLIS1 IL6R

4.44e-062001467b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLEC18A PDE3A CLEC18B CLEC18C SORBS1 GLIS1 IL6R

4.44e-062001467f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellfacs-Skin-Anagen-24m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIS3 VWDE CLCA2 MAFB IL6R NOTCH3

6.63e-061391466da8874d441b8e69c94bad771635f378ddafb49fe
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-St18_(Lateral_CA3_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CLEC18A SEC31B TGM5 DUOXA2

9.82e-06411464083d2aab96ba9449797f955507c4a1be51ac5c8d
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ3 RIPK2 SIRPA TECTA SH3BP4 MAFB

1.33e-051571466a98d06cef80bfe8481b0940abce2b29675e45812
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A NBEA IRAG1 SLA ROBO1 NOTCH3

1.43e-0515914665ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

DENND2A PDE3A ADAMTSL1 SORBS1 IRAG1 NOTCH3

1.48e-051601466fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCelldroplet-Kidney-nan-18m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIRPA RUNX1 ITGAM ITGAX MAFB IL6R

1.48e-051601466d18c4cc99a31481dd0ee8af9299695d5f6857b42
ToppCelldroplet-Kidney-nan-18m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIRPA RUNX1 ITGAM ITGAX MAFB IL6R

1.48e-051601466a707a4ad9fbedcca227f76b49f1393e88101c2fb
ToppCelldroplet-Kidney-nan-18m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIRPA RUNX1 ITGAM ITGAX MAFB IL6R

1.48e-05160146673b604cbdcd9e8f0f317964abc632abee314a557
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SIRPA ITGAM ITGAX MAFB

1.53e-051611466787f91f906756ef570c0d02936c3cdfafb3f7454
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SIRPA ITGAM ITGAX MAFB

1.53e-0516114663db97af49520dc8cbafb4454d8afd9d588160e89
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SIRPA ITGAM ITGAX MAFB

1.53e-051611466f1d258c81bcf0f3c52bd20aa58faa9a5fd888168
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TIMD4 ITGAM SLA ITGAX CCL5 IL6R

1.59e-0516214662b47fd256490d0c2d9ad5950aa26410aeb6ec995
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE3A CRIM1 IRAG1 SLC5A5 CLMN NOTCH3

1.64e-05163146651dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellfacs-Kidney-nan-24m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 RUNX1 ITGAM ITGAX MAFB IL6R

1.76e-051651466a359dda24c2c10b7b8df902a7c4c2ebf27b041f3
ToppCellfacs-Kidney-nan-24m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 RUNX1 ITGAM ITGAX MAFB IL6R

1.76e-0516514661d5880aa49e6e6e95bde14a40fbe6e40b71c6d22
ToppCellfacs-Kidney-nan-24m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 RUNX1 ITGAM ITGAX MAFB IL6R

1.76e-051651466cdc09cbfd6eaeb8e436d83bbca7146bde3b3f01e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ASTL IRAG1 SLA CLMN ROBO1

1.76e-051651466e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ASTL IRAG1 SLA CLMN ROBO1

1.76e-051651466b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ASTL IRAG1 SLA CLMN ROBO1

1.76e-051651466d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ3 RIPK2 SIRPA TECTA SH3BP4 MAFB

1.82e-05166146628a44448a0b0d72459e8fe84ce5d666f16f514b3
ToppCelldroplet-Kidney-nan-3m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 SIRPA RUNX1 ITGAX MAFB IL6R

1.82e-051661466f55fc58572ae6080ac2758462a6b1f3f8b5a93f3
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SLA ITGAX CCL5 IL9R

1.82e-05166146600c53ee34ff4b988a9accd296bc0a2e14d9e7c49
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ3 RIPK2 SIRPA TECTA SH3BP4 MAFB

1.82e-0516614662a04915d534a83e65aa168435d6856125b5bdd78
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 RUNX1 ITGAM SLA MAFB IL6R

1.95e-0516814668ee57814c7e9d45444f48b6b269c4d535bc4d5e1
ToppCellfacs-Heart-RV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 RUNX1 ITGAM SLA MAFB IL6R

1.95e-051681466c1a5f4f4d32a1f8583048db709a7037cc9357ad8
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 RUNX1 ITGAM SLA MAFB IL6R

1.95e-051681466a405f0de70293f68b4e000c1fc8a9ad33d56539a
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPBWR1 PDE3A STON1 IRAG1 SLC5A5 ROBO1

2.02e-05169146687116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANK1 LAT2 RUNX1 ITGAM SLA ITGAX

2.09e-0517014669e94fa0d05abed3438b28296a293767096d517d6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A NBEA IRAG1 SLA ROBO1 NOTCH3

2.09e-051701466876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A NBEA IRAG1 SLA ROBO1 NOTCH3

2.09e-0517014661f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIK1 SIRPA RUNX1 GTF2H2 IL6R HOMEZ

2.16e-051711466bf475a69db04d4a886e442704955c6a96ff0de46
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC18A PDE3A IRAG1 GLIS1 NOTCH2 NOTCH3

2.16e-0517114664ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

PDE3A ADAMTSL1 CRIM1 SORBS1 IRAG1 NOTCH3

2.23e-051721466c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

DENND2A PDE3A CRIM1 IRAG1 SLCO1C1 NOTCH3

2.23e-051721466858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SIRPA RUNX1 ITGAM MAFB

2.30e-0517314661ea8b8b89611bebf6acb700fb04a7d38720775a9
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A SH3RF1 ANK2 SEMA4G TBC1D16 NOTCH3

2.30e-0517314663059325901b1e5e12a1a91183f14267288b2f600
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SIRPA RUNX1 ITGAM MAFB

2.30e-0517314669b957dd442f3af0e5fb99f3c93606308a459d485
ToppCellfacs-Heart-RA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 SIRPA RUNX1 ITGAM SLA IL6R

2.30e-0517314664fa5f502fa3ff8f888e279f68a0dafd91b37f26f
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 LAT2 SIRPA RUNX1 ITGAM MAFB

2.30e-051731466a0e4d25db186b9f7ff819abc0db68ad58c92ba3b
ToppCellfacs-Heart-RA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 SIRPA RUNX1 ITGAM SLA IL6R

2.30e-0517314665058cb5e3f2d57dbe947e1b113eb2bef7bf6dd7d
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DENND2A PDE3A SORBS1 IRAG1 CLMN NOTCH3

2.30e-0517314665416b092321c7d9b63f0418c60f2402a138355bf
ToppCellfacs-Heart-RA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMD4 SIRPA RUNX1 ITGAM SLA IL6R

2.30e-051731466ea406b47ff3ead992bc06f6b1707c76eee574782
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A SH3RF1 ANK2 SEMA4G TBC1D16 NOTCH3

2.30e-05173146636c8338463ee4cc432f568728d55989360f9a68d
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A NBEA IRAG1 CLMN ROBO1 NOTCH3

2.38e-0517414668393f0b43c767839c1630bcb952d62b42efc788d
ToppCellfacs-Kidney-nan-18m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 SIRPA RUNX1 ITGAM MAFB IL6R

2.46e-0517514662cb0d07a47bc645cfa690bb853e11d657af19ede
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGAM ITGAX SALL2 EXO1 WDR62 MYBL2

2.46e-051751466f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCellfacs-Kidney-nan-18m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 SIRPA RUNX1 ITGAM MAFB IL6R

2.46e-051751466cec941edec6849f2fb602c08fd1eed6d0345f934
ToppCellfacs-Kidney-nan-18m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 SIRPA RUNX1 ITGAM MAFB IL6R

2.46e-05175146624d58e2f6d36124bde0f2c6f5357b9161bc5f476
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG9B LAT2 SIRPA RUNX1 ITGAM IL6R

2.54e-051761466d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG9B LAT2 SIRPA RUNX1 ITGAM IL6R

2.54e-0517614664f37854124d77ee64dcb40fd491eaed2ba389891
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG9B LAT2 SIRPA RUNX1 ITGAM IL6R

2.54e-0517614660afba8707b847e5bdf6f38fe4379967631fe2240
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAT2 SIRPA RUNX1 ITGAM SLA ITGAX

2.54e-051761466a85ad8b4815fde72edd5c900e882a0bc04033ea8
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTSL1 GLIS3 NBEA SLC5A5 CLCA2 LNX1

2.62e-051771466779ba86f53650772755b52460be03f18bb204e55
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTSL1 GLIS3 NBEA SLC5A5 CLCA2 LNX1

2.62e-0517714660f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD2 CCDC175 CCDC168 PLXND1 CD58 FRMPD2B

2.70e-0517814660e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCellfacs-Skin-Anagen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIP1 CEACAM19 CLCA2 MAFB IL6R NOTCH3

2.79e-0517914664a072526c3a524a7aed99bdb32a07a1ce1f48972
DrugPirlindole mesylate [60762-57-4]; Down 200; 12.4uM; HL60; HT_HG-U133A

ANK2 SIK1 RUNX1 RGP1 FAAP100 FBXL6 JAM2 SSH3 CABIN1

3.39e-0619913793140_DN
Drug2-propylpentanoic acid; Down 200; 10000uM; HL60; HG-U133A

MXRA5 LAT2 PPRC1 NUP62 RUNX1 SRCAP SLA IL6R

1.95e-051891378410_DN
DrugHomosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A

DENND2A LAT2 NSD1 PROSER1 RUNX1 UBOX5 SSH3 DNPEP

2.44e-0519513784533_DN
DrugScopoletin [92-61-5]; Down 200; 20.8uM; MCF7; HT_HG-U133A

STON1 BCORL1 ASH1L UBOX5 FBXL6 CLMN IL6R NOTCH2

2.44e-0519513786510_DN
DrugPerhexiline maleate [6724-53-4]; Down 200; 10.2uM; PC3; HT_HG-U133A

DENND2A LAT2 BCORL1 ASH1L PLXND1 SRCAP UBOX5 CABIN1

2.53e-0519613785081_DN
DrugSulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A

MXRA5 STON1 PMEL RUNX1 UBOX5 CLCA2 RAVER2 CCL5

2.63e-0519713783940_UP
Drug16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

STON1 RUNDC3B RNPEPL1 PLXND1 RGS3 SSH3 CCL5 WDR62

2.63e-0519713787546_DN
Drugaspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A

HIVEP2 RUNX1 SEC31B FAAP100 DGLUCY ATXN7 CABIN1 FBXW7

2.63e-0519713781145_DN
DrugBemegride [64-65-3]; Down 200; 25.8uM; PC3; HT_HG-U133A

DENND2A STON1 RUNX1 UBOX5 ATXN7 SSH3 CABIN1 NOTCH3

2.72e-0519813786668_DN
DrugHydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; HL60; HT_HG-U133A

ITCH HIVEP2 KIF1A BCORL1 SEC31B SEMA4G DLL3 NOTCH2

2.72e-0519813782349_UP
Drugtetraethylenepentamine pentahydrochloride; Down 200; 100uM; ssMCF7; HG-U133A

NOL6 PLXND1 RUNX1 SRCAP UBOX5 CLIP1 PRDM2 SSH3

2.82e-051991378498_DN
DrugGlycocholic acid [475-31-0]; Up 200; 8.6uM; HL60; HT_HG-U133A

DENND2A ANK1 KIF1A LAMB2 RUNX1 SRCAP TNKS NOTCH2

2.82e-0519913782454_UP
DrugTropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A

LAT2 ATXN7L1 SORBS1 SRCAP SLA RAVER2 MAFB WDR62

2.93e-0520013783619_UP
DrugRP 55778

ITGAM ITGAX CD58

9.20e-05151373CID000121869
DrugMiconazole [22916-47-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A

SIK1 SRCAP CBLB PRDM2 MAFB CCL5 IL6R

1.11e-0418013771477_UP
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; HL60; HT_HG-U133A

LAT2 PPRC1 SIRPA RUNX1 SLA TGM5 IL6R

1.37e-0418613772694_DN
DrugDrofenine hydrochloride [548-66-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A

PLXND1 UBOX5 PAICS PRDM2 CCL5 IL6R WDR62

1.61e-0419113776776_UP
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

KIF1A NOL6 SRCAP FAAP100 FBXL6 IL6R WDR62

1.71e-0419313775239_DN
DrugZalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A

STON1 KIF1A RUNDC3B PMEL RUNX1 SRCAP CABIN1

1.77e-0419413777352_UP
DrugStreptozotocin [18883-66-4]; Up 200; 15uM; PC3; HT_HG-U133A

HIVEP2 RUNX1 SRCAP SEMA4G SLC5A5 SALL2 SSH3

1.77e-0419413775836_UP
DrugPyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; HL60; HG-U133A

NOL6 BCORL1 NUP62 RUNX1 ITGAM SEC31B DNPEP

1.77e-0419413771759_UP
DrugQuinethazone [73-49-4]; Down 200; 13.8uM; PC3; HT_HG-U133A

DENND2A STON1 ASH1L SRCAP RGP1 DNPEP FBXW7

1.77e-0419413774529_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A_EA

SERTAD2 PRDM2 CEP63 ATXN7 SSH3 ROBO1 NOTCH3

1.83e-0419513771053_DN
DrugCisapride [81098-60-4]; Down 200; 8.6uM; PC3; HT_HG-U133A

ITCH ATXN7L1 PLXND1 FAAP100 CLIP1 NOTCH2 WDR62

1.83e-0419513776706_DN
DrugIsoniazid [54-85-3]; Down 200; 29.2uM; PC3; HT_HG-U133A

DENND2A HIVEP2 BCORL1 SIRPA RUNX1 NOTCH2 NOTCH3

1.83e-0419513775840_DN
DrugDihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A

ATXN7L1 SIK1 SORBS1 RGS3 MAFB CABIN1 IL6R

1.89e-0419613772793_UP
Drugarachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A

LAMB2 RUNX1 UBOX5 RGS3 JAM2 CDH22 DNPEP

1.89e-041961377443_DN
DrugTrimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A

ASH1L RUNX1 PRDM2 CLCA2 PLXNB1 NOTCH3 WDR62

1.89e-0419613774100_DN
DrugPhenelzine sulfate [156-51-4]; Down 200; 17uM; PC3; HT_HG-U133A

STON1 PLXND1 RUNX1 FAAP100 NOTCH2 DNPEP FBXW7

1.89e-0419613774538_DN
DrugStachydrine hydrochloride; Down 200; 22.2uM; PC3; HT_HG-U133A

DENND2A SIRPA PLXND1 CLIP1 SSH3 CABIN1 DNPEP

1.89e-0419613774469_DN
DrugHesperidin [520-26-3]; Down 200; 6.6uM; MCF7; HT_HG-U133A

HIVEP2 ASH1L PLXND1 PMEL RGS3 MAFB PLXNB1

1.89e-0419613772648_DN
Drughaloperidol; Down 200; 10uM; HL60; HT_HG-U133A

RNPEPL1 SIRPA RUNX1 SRCAP SEMA4G SALL2 SSH3

1.89e-0419613776203_DN
DrugIoversol [87771-40-2]; Down 200; 5uM; HL60; HT_HG-U133A

CRIM1 KIF1A RUNX1 UBOX5 CLIP1 TNKS NOTCH2

1.95e-0419713773026_DN
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A

CRIM1 BCORL1 PMEL RUNX1 SRCAP SALL2 MAFB

1.95e-0419713773355_DN
DrugAcetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; PC3; HT_HG-U133A

STON1 ASH1L PLXND1 RUNX1 ITGAM DLL3 PLXNB1

1.95e-0419713772061_UP
DrugN-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; PC3; HT_HG-U133A

HIVEP2 RUNX1 SLA SSH3 PLXNB1 DNPEP FBXW7

1.95e-0419713774622_DN
DrugPyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A

LAT2 PLXND1 RUNX1 UBOX5 PAICS PRDM2 WDR62

1.95e-0419713776801_UP
DrugPronethalol hydrochloride [51-02-5]; Down 200; 15uM; HL60; HT_HG-U133A

TWNK PROSER1 FAAP100 DGLUCY SALL2 SSH3 IL6R

1.95e-0419713772902_DN
DrugCinchonine [118-10-5]; Down 200; 13.6uM; HL60; HT_HG-U133A

HIVEP2 RUNX1 SRCAP UBOX5 SALL2 SSH3 TNKS

1.95e-0419713772133_DN
DrugLY 294002; Down 200; 0.1uM; HL60; HT_HG-U133A

LAT2 RIPK2 RUNX1 SRCAP RGS3 SSH3 NOTCH2

1.95e-0419713776175_DN
DrugDeltaline [6836-11-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A

LAT2 ATXN7L1 PMEL SRCAP CLMN CABIN1 IL6R

1.95e-0419713773831_DN
DrugBezafibrate [41859-67-0]; Up 200; 11uM; PC3; HT_HG-U133A

EREG PMEL RUNX1 SRCAP PRDM2 CLMN FBXW7

1.95e-0419713776653_UP
DrugMeclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A

SIK1 PLXND1 UBOX5 CLMN TNKS CABIN1 NOTCH3

1.95e-0419713777038_DN
DrugFlutamide [13311-84-7]; Up 200; 14.4uM; HL60; HT_HG-U133A

ANK2 KIF1A RNPEPL1 RUNX1 SEC31B SEMA4G SSH3

2.01e-0419813772358_UP
DrugMeticrane [1084-65-7]; Up 200; 14.6uM; MCF7; HT_HG-U133A

LAT2 RUNX1 SLA UBOX5 SLC5A5 PLXNB1 NOTCH3

2.01e-0419813775984_UP
Drug(R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; HL60; HT_HG-U133A

ANK2 KIF1A RIPK2 RUNX1 SRCAP SLC5A5 SSH3

2.01e-0419813772496_UP
DrugGabazine [105538-73-6]; Up 200; 10.8uM; PC3; HT_HG-U133A

STON1 LAT2 ATXN7L1 PLXND1 UBOX5 DLL3 PLXNB1

2.01e-0419813774236_UP
DrugThiamphenicol [15318-45-3]; Down 200; 11.2uM; PC3; HT_HG-U133A

HIVEP2 RUNX1 SRCAP FAAP100 PRDM2 CABIN1 NOTCH3

2.01e-0419813771826_DN
DrugPiracetam [7491-74-9]; Up 200; 28.2uM; HL60; HG-U133A

BCORL1 RUNX1 SEC31B CLIP1 RGS3 FBXL6 SALL2

2.01e-0419813771710_UP
Drug(S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; HL60; HT_HG-U133A

NOL6 SRCAP UBOX5 FAAP100 PRDM2 CABIN1 NOTCH2

2.01e-0419813772961_DN
Drug(-)-Quinpirole hydrochloride [85760-74-3]; Up 200; 15.6uM; MCF7; HT_HG-U133A

ANK1 KIF1A NOL6 SEMA4G MAFB PLXNB1 DNPEP

2.01e-0419813777481_UP
DrugChlorogenic acid [327-97-9]; Down 200; 11.2uM; HL60; HT_HG-U133A

HIVEP2 NSD1 RUNX1 SRCAP ITGAM SALL2 TNKS

2.01e-0419813771346_DN
Drug(S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; MCF7; HT_HG-U133A

HIVEP2 LAT2 RUNX1 RGP1 PAICS SLC5A5 WDR62

2.01e-0419813775444_DN
DrugMRK 003

TSHZ3 ATG9B SORBS1 TBC1D16 CDH22 DLL3 ROBO1 MAFB CCL5 IL6R PLXNB1 NOTCH2 NOTCH3 FBXW7

2.02e-0476013714ctd:C523799
DrugMoroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; MCF7; HT_HG-U133A

RUNDC3B ATXN7L1 PMEL RUNX1 UBOX5 PAICS SLC5A5

2.07e-0419913771527_UP
DrugGuanethidine sulfate [60-02-6]; Up 200; 13.4uM; HL60; HG-U133A

PPRC1 RUNX1 ITGAM SEC31B PRDM2 SSH3 IL6R

2.07e-0419913771554_UP
DrugBenzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; PC3; HT_HG-U133A

LAT2 PPRC1 NOL6 SEMA4G SSH3 CABIN1 NOTCH3

2.07e-0419913774294_DN
DrugDesipramine hydrochloride [58-28-6]; Down 200; 13.2uM; PC3; HT_HG-U133A

RNPEPL1 UBOX5 FAAP100 SSH3 CABIN1 NOTCH3 FBXW7

2.07e-0419913776693_DN
DrugEdrophonium chloride [116-38-1]; Down 200; 19.8uM; PC3; HT_HG-U133A

ATXN7L1 PLXND1 RUNX1 UBOX5 SEMA4G SLC5A5 CABIN1

2.07e-0419913776655_DN
DrugProparacaine hydrochloride [5875-06-9]; Down 200; 12uM; MCF7; HT_HG-U133A

STON1 BCORL1 RUNX1 UBOX5 SEMA4G PRDM2 CLMN

2.07e-0419913776492_DN
DrugEnilconazole [35554-44-0]; Down 200; 13.4uM; MCF7; HT_HG-U133A

HIVEP2 SRCAP RGS3 PRDM2 CABIN1 NOTCH2 FBXW7

2.07e-0419913775538_DN
DrugCitalopram hydrobromide [59729-32-7]; Down 200; 1uM; PC3; HT_HG-U133A

DENND2A RUNDC3B RUNX1 SSH3 NOTCH2 DNPEP FBXW7

2.07e-0419913774555_DN
DrugChlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A

SRCAP ITGAM UBOX5 PAICS SEMA4G IL6R WDR62

2.07e-0419913776773_UP
DrugProcainamide hydrochloride [614-39-1]; Up 200; 14.8uM; HL60; HT_HG-U133A

ITCH ASH1L SIK1 DGLUCY SALL2 SSH3 CD58

2.13e-0420013771263_UP
DrugUrosiol [128-13-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A

ASH1L SRCAP UBOX5 SEMA4G SALL2 PLXNB1 NOTCH3

2.13e-0420013776484_DN
DrugAzaguanine-8 [134-58-7]; Up 200; 26.2uM; MCF7; HT_HG-U133A

MXRA5 HIVEP2 ATXN7L1 RUNX1 SRCAP PAICS PRDM2

2.13e-0420013777444_UP
Druggamma-secretase inhibitor I

NOTCH2 NOTCH3

2.14e-0441372CID011754711
DiseaseMalignant neoplasm of breast

NPBWR1 EREG ANK1 ANK2 BCORL1 SORBS1 MAGEE1 TECTA CLIP1 SLC5A5 ARHGDIA CLCA2 EXO1 ROBO1 PLXNB1 NOTCH2 NOTCH3 FBXW7

2.08e-06107413518C0006142
Diseasespinocerebellar ataxia type 7 (implicated_via_orthology)

ATXN7L1 ATXN7

2.08e-0521352DOID:0050958 (implicated_via_orthology)
Diseasefibromuscular dysplasia

STON1 FRMPD2 FRMPD2B LNX1

4.94e-05441354EFO_1000938
DiseaseAbnormality of refraction

TSHZ3 PDE3A ADAMTSL1 TDRD9 FRMPD2 GLIS3 NBEA RUNX1 RGS3 ROBO1 FRMPD2B GLIS1

6.47e-0567313512HP_0000539
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

ASH1L PLXND1 SRCAP PLXNB1

7.57e-05491354DOID:0060037 (implicated_via_orthology)
DiseasePrimary microcephaly

CEP63 TUBGCP6 WDR62

1.35e-04221353C0431350
DiseaseDrugs used in diabetes use measurement

TSHZ3 HIVEP2 ANK1 GLIS3 NSD1 ATXN7 NOTCH2

1.79e-042551357EFO_0009924
DiseaseThyroid Dyshormonogenesis 1

SLC5A5 DUOXA2

3.08e-0461352C1848805
Diseaselobe attachment

HIVEP2 NBEA RUNX1 ROBO1 LNX1 GLIS1

3.93e-042071356EFO_0007667
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH2 NOTCH3

4.30e-0471352DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH2 NOTCH3

4.30e-0471352DOID:3620 (implicated_via_orthology)
Diseasestroke

PDE3A STON1 ANK2 RUNX1 C4orf54

5.38e-041441355EFO_0000712
Diseasemitochondrial DNA measurement

NPBWR1 RNPEPL1 SERTAD2 TWNK SIRPA RUNX1 TUBGCP6

8.09e-043281357EFO_0006312
DiseaseNeurodevelopmental Disorders

ANK2 ASH1L SRCAP PLXNB1

8.93e-04931354C1535926
Diseasepancreatic hormone measurement

FRMPD2 FRMPD2B

9.13e-04101352EFO_0020621
DiseaseAdenoid Cystic Carcinoma

BCORL1 NSD1 SRCAP FBXW7

1.17e-031001354C0010606
Diseasefree cholesterol in small VLDL measurement

TIMD4 CEACAM19 MAFB

1.31e-03471353EFO_0022272
Diseasefree cholesterol in medium VLDL measurement

TIMD4 CEACAM19 MAFB

1.31e-03471353EFO_0022269
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement

TIMD4 R3HDM2 MAFB TNKS

1.45e-031061354EFO_0008317, EFO_0008596
Diseaseplatelet crit

DENND2A STON1 TIMD4 RNPEPL1 SERTAD2 SIRPA RUNX1 ITGAX SH3BP4 TULP4 MAFB NOTCH3

1.46e-0395213512EFO_0007985
Diseasecognitive inhibition measurement

HIVEP2 SERTAD2 TGM5

1.57e-03501353EFO_0007969
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipid measurement

TIMD4 R3HDM2 MAFB TNKS

1.61e-031091354EFO_0004639, EFO_0008317, EFO_0008596
Diseasecholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

TIMD4 R3HDM2 MAFB TNKS

1.66e-031101354EFO_0008317, EFO_0008596, EFO_0010351
Diseasefree cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

TIMD4 R3HDM2 MAFB TNKS

1.66e-031101354EFO_0008317, EFO_0008591, EFO_0008596
Diseasechylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement

TIMD4 R3HDM2 MAFB TNKS

1.66e-031101354EFO_0004574, EFO_0008317, EFO_0008596
DiseaseGlioblastoma Multiforme

SIK1 RUNX1 NOTCH2 NOTCH3

1.72e-031111354C1621958
Diseasefemoral neck bone geometry

NSD1 RUNX1

1.82e-03141352EFO_0004511
Diseasecholesterol in small VLDL measurement

TIMD4 CEACAM19 MAFB

1.86e-03531353EFO_0022228
Diseaseresponse to TNF antagonist

PDE3A SLCO1C1 MAFB

1.96e-03541353EFO_0004653
Diseaserefractive error, age at onset, Myopia

PDE3A ADAMTSL1 TDRD9 FRMPD2 FRMPD2B

1.98e-031931355EFO_0004847, HP_0000545, MONDO_0004892
Diseasepeak expiratory flow

TSHZ3 PDE3A STON1 SH3RF1 GLIS3 RUNX1 IRAG1 TULP4

2.13e-034981358EFO_0009718
Diseaseureidopropionic acid measurement

MAFB OTOG

2.39e-03161352EFO_0010542
Diseaseendometriosis (biomarker_via_orthology)

RUNX1 CCL5

2.39e-03161352DOID:289 (biomarker_via_orthology)
Diseasehematocrit

HIVEP2 RNPEPL1 BCORL1 ASH1L SERTAD2 GLIS3 R3HDM2 SORBS1 RUNX1 IRAG1 RGS3 TRMT61B

2.40e-03101113512EFO_0004348
Diseasemean platelet volume

HIVEP2 RNPEPL1 BCORL1 SORBS1 SIRPA PLXND1 RUNX1 IRAG1 SRCAP RGS3 IL6R HOMEZ

2.58e-03102013512EFO_0004584
Diseaseuridine diphosphate galactose measurement, uridine diphosphate glucose measurement

IGFN1 SIRPA

2.70e-03171352EFO_0010543, EFO_0010544
Diseasecervical artery dissection

IRAG1 LNX1

2.70e-03171352EFO_1000059
Diseasehemoglobin A1 measurement

TSHZ3 PDE3A ANK1 TIMD4 PLXND1 ITGAX TULP4 NOTCH2

2.78e-035201358EFO_0007629
DiseaseCerebrovascular accident

PDE3A ANK2 NOTCH3

2.91e-03621353C0038454
DiseaseTinnitus

NPBWR1 CBLB ITGAX TNKS

3.05e-031301354HP_0000360
Diseaseserum IgE measurement

NPBWR1 PDE3A CRIM1

3.18e-03641353EFO_0004579
Diseaseserum gamma-glutamyl transferase measurement

ASH1L SERTAD2 GLIS3 TWNK CBLB FAAP100 SEMA4G ROBO1 YY1AP1 CABIN1 NOTCH2

3.26e-0391413511EFO_0004532
Diseasecortical surface area measurement

PDE3A ADAMTSL1 ITCH STON1 GLIS3 PLXND1 IRAG1 RGP1 SLA STPG2 TBC1D16 ROBO1 TNKS LNX1

3.50e-03134513514EFO_0010736
Diseasetriglycerides in very small VLDL measurement

TIMD4 R3HDM2 MAFB

3.78e-03681353EFO_0022144
Diseasesystemic lupus erythematosus

STON1 LAT2 SRCAP ITGAM ITGAX SLC17A1 CD58 TNKS IL6R NOTCH2

3.79e-0379913510MONDO_0007915
DiseaseIschemic stroke

PDE3A STON1 ANK2 VWDE STPG2 LNX1

3.85e-033241356HP_0002140
Diseaserefractive error

ADAMTSL1 TDRD9 FRMPD2 NBEA FAAP100 FRMPD2B

3.97e-033261356MONDO_0004892
DiseaseFEV/FEC ratio

TSHZ3 PDE3A ITCH HIVEP2 TIMD4 CRIM1 SERTAD2 GLIS3 NSD1 R3HDM2 MAFB TRMT61B LNX1

4.23e-03122813513EFO_0004713
Diseasechronic obstructive pulmonary disease

TSHZ3 ADAMTSL1 HIVEP2 STON1 CRIM1 SERTAD2 GLIS3 MAFB LNX1

4.48e-036881359EFO_0000341
DiseaseAutosomal Recessive Primary Microcephaly

CEP63 WDR62

4.52e-03221352C3711387

Protein segments in the cluster

PeptideGeneStartEntry
PPGTILSLSSSSPCL

nan

206

Q6ZR03
ESLSGPALGTPLSIC

AMER3

446

Q8N944
EILPSPICSQSSGTS

ASH1L

1101

Q9NR48
TPCGTTIGPILASRL

DNPEP

421

Q9ULA0
LLSPASLGCALSSPL

ANK1

1521

P16157
SCGQPLSVATLPTTL

BCORL1

456

Q5H9F3
TPSTVSSVISGCPGL

FBXL6

486

Q8N531
PLCTVPVSTSSCLSP

DLL3

246

Q9NYJ7
LISLTQACLSPSSGS

DNHD1

4336

Q96M86
SLPGVILGAPLASSC

ASTL

16

Q6HA08
VGGSSDSCPLSVPSL

ATXN7L1

736

Q9ULK2
APSPVTSLSSVCTGL

R3HDM2

771

Q9Y2K5
TSLSSVCTGLSPLPV

R3HDM2

776

Q9Y2K5
NLASVLPSVCLSSPA

RAVER2

586

Q9HCJ3
IVCTSLSPGGPTALA

NSD1

111

Q96L73
SVLSTSCGLSLSLPI

RGS3

86

P49796
LASTTSPSQLLACGP

ITGAX

96

P20702
PTLRLLCSITGGTTP

ANK2

1256

Q01484
LTSALSPVICGPNRS

NOTCH2

2076

Q04721
LPVTLGQPASISCRS

IGKV2D-30

31

A0A075B6S6
LESLPSPTLTCALTN

CD58

121

P19256
CTRLQPAGSVSSTPL

MAFB

46

Q9Y5Q3
GPPTISKGLCTSVTL

MAGEE1

116

Q9HCI5
LPSIKCTGPLANSLS

CBLB

681

Q13191
TGLSTVVNSTLCPPL

ADAMTSL1

821

Q8N6G6
AGVSCSPTPTIVLTG

IRAG1

71

Q9Y6F6
SSQLITCRTPALPGL

PLXNB1

1331

O43157
VLNSTLITCPSPGAL

PLXND1

1116

Q9Y4D7
LITCPSPGALSNASA

PLXND1

1121

Q9Y4D7
SSGLCSIPNPSIISS

MINDY4B

76

A8MYZ0
CSSPLQGTPASSLVS

PDE3A

526

Q14432
GISLCLSSDPSLPAL

NOL6

391

Q9H6R4
LACPGPLADSSVTLS

NOTCH3

2086

Q9UM47
GCASLTATAPSPEVS

LNX1

151

Q8TBB1
LPLAVASAGCATTPA

LY6L

11

H3BQJ8
PSEACAPLLISLSTL

LAMB2

761

P55268
CVLSTPPTLSLLTIG

TUBGCP6

446

Q96RT7
ALVTLSTGPTCSILP

NLRP5

21

P59047
VPSCEVPSSALSGTV

JAM2

136

P57087
TGLPTLTLPRGTTCL

TWNK

276

Q96RR1
RSCPLGSPAVLAVTT

PRR25

381

Q96S07
GLSLCTPVTTAGAPT

NUP62

236

P37198
LLSSGTGPRPISCTT

FAAP100

496

Q0VG06
KSAVGPTCPATVSSL

ATXN7

271

O15265
CEPVARPSLTSISSG

MEDAG

6

Q5VYS4
TSVPISLSACLNPAL

PROSER1

646

Q86XN7
CLPGLSDSPISASRV

ITCH

181

Q96J02
SPGICTSKPSSILSG

BTBD18

271

B2RXH4
SISSVPLCPLRLGSS

DUOXA2

226

Q1HG44
PLCPLRLGSSALTTQ

DUOXA2

231

Q1HG44
TSLPGDSVTLTCPGV

IL6R

36

P08887
AAATTIITCPPSASA

CABIN1

1971

Q9Y6J0
AVSTGPSLELCTLPS

CCDC175

21

P0C221
PSLELCTLPSTLGSS

CCDC175

26

P0C221
VVTGLTLVCSSAPGP

ARHGDIA

71

P52565
CSPTPFLIGLLSSSL

DENND2A

811

Q9ULE3
SCSLPVSPLGSIATR

CEP63

651

Q96MT8
AVSLVTALPGRPSSC

FRMPD2B

66

Q6IN97
TALPGRPSSCVSVTD

FRMPD2B

71

Q6IN97
VSLVTALPGRPSSCV

FRMPD2

1056

Q68DX3
LGLISPPASQVSTAC

GLIS3

6

Q8NEA6
TTGLVPCSATPTTFG

FBXW7

196

Q969H0
SASAGPPILSGTCLT

CRIM1

596

Q9NZV1
SLSILCSAVSPVPSV

CEACAM19

201

Q7Z692
ILIATALCAPASASP

CCL5

11

P13501
APCPAAATASLLASI

ATG9B

786

Q674R7
LGTLPSTGSTTLPQC

CEP192

1266

Q8TEP8
LGLGPEASLSTAPSC

GPR156

556

Q8NFN8
SPVTLGQPASISCRS

IGKV2-24

31

A0A0C4DH68
PSLTLVCTPVSCVSS

KRTAP10-10

36

P60014
PSLSLVCTPVSCVSS

KRTAP10-11

41

P60412
LPVTLGQPASISCRS

IGKV2-30

31

P06310
VCSLTIPSVSPKDSG

IGFN1

1211

Q86VF2
PPTLSSTGTLTIRIC

CDH22

586

Q9UJ99
LSTTVIPSCIPGESS

EREG

31

O14944
ASGLSSSPAGLICLP

HOMEZ

31

Q8IX15
SVLLTNACASIPSPS

CCDC168

4081

Q8NDH2
SGLFLLCSPTSLTIP

ESRG

86

Q1W209
PSPLTSLGAVSSCET

DGLUCY

226

Q7Z3D6
SLVTCVNGLRSPPLT

GLIS1

96

Q8NBF1
PNSSAATLCSLPPLS

C4orf54

1496

D6RIA3
SLVPGCSPSITSTGL

SALL2

981

Q9Y467
SAPCLAPSSLLSPEA

PPRC1

1366

Q5VV67
GLQTTPASRATSPLC

CLIP1

136

P30622
PLGVATLTPSSTCPS

KIF1A

1496

Q12756
TLTPSSTCPSLVEGR

KIF1A

1501

Q12756
PSCSLSLPLSISTTE

PRDM2

661

Q13029
LSCSNASTLAPLPAP

NPBWR1

21

P48145
CSSTPLGAVLVRSPI

OTOG

2791

Q6ZRI0
LSLALKTGPTSGLCP

LAT2

166

Q9GZY6
LTTPCLTQSTAAPAV

SLA

171

Q13239
PSLLGLCGSLTSVAS

RUNDC3B

431

Q96NL0
ILPPCTNASTGSALL

RUNX1

401

Q01196
GSGALPSLTCSLTPL

RTN4R

446

Q9BZR6
PSLTCSLTPLGLALV

RTN4R

451

Q9BZR6
APSIGLPTSTIASCS

SEC13

221

P55735
LSPPPASSSSECSLI

GTF2H2C;

236

Q6P1K8
EGPSTCLVSLLLTPS

STK11IP

956

Q8N1F8
PCLLPTATSKLSGAV

RNPEPL1

281

Q9HAU8
ASCFSATSPLVLPTT

UBOX5

381

O94941
VSSLGSCSTGSPVPV

PRSS29P

46

A6NIE9
RPSLCSGPELSTSVL

SH3BP4

726

Q9P0V3
PSLAKLSSVTCIPGT

TDRD9

111

Q8NDG6
IISATGASALPLCPS

MAP3K21

906

Q5TCX8
SLKLPPVGSTASLCV

PLEKHG4

646

Q58EX7
PLSSTPGFCTAIVSL

RGP1

306

Q92546
LPGLLSPSCLLSSGQ

RIPPLY1

31

Q0D2K3
LELESPSLTSTPVCS

MYBL2

466

P10244
ACGGILPLLSAATSP

NBEA

1396

Q8NFP9
CLSSVLSLLIPPAAG

SLC17A1

116

Q14916
LSPLTAPCIVVSPST

SIK1B

481

A0A0B4J2F2
LSPLTAPCIVVSPST

SIK1

481

P57059
ATLRCTATSLIPVGP

SIRPA

51

P78324
GAPCSSVLPTTGILT

SEC31B

971

Q9NQW1
TQSSGPIPALACGLS

IL9R

461

Q01113
LSLAATTSPPQLLAC

ITGAM

91

P11215
AQTCLVTPSSPLLLG

SRCAP

2516

Q6ZRS2
VLQAAIPLTSCGSSP

PMEL

291

P40967
TISPPTLGTLRSCFS

EXO1

596

Q9UQ84
LACAAAAPLTSPSIT

SH3RF1

656

Q7Z6J0
FPDSSSPSCTLGLVL

SSH3

151

Q8TE77
LPSESAGLATASCPI

ANKHD1

1921

Q8IWZ3
LSSSPPSSCVSLETL

CLMN

686

Q96JQ2
LGNCLPTVLSSGSTI

CLCA2

426

Q9UQC9
AALCGTPTPSLASGL

CLEC18A

86

A5D8T8
AALCGIPTPSLASGL

CLEC18B

86

Q6UXF7
AALCGIPTPSLASGL

CLEC18C

86

Q8NCF0
VSADALLTLPPSTSC

C11orf53

121

Q8IXP5
SCPLILCTTGSRPSS

TECTA

1121

O75443
LRLPSGLGCSTVLSP

PAICS

366

P22234
GSSTCSSLQLPPVAL

TULP4

1246

Q9NRJ4
PTPSGLTEYSTLTLC

VWDE

796

Q8N2E2
TISLSCLSALGTPSP

VSIG1

156

Q86XK7
SCPSLPLSISDIGTG

TRMT61B

66

Q9BVS5
PLSISDIGTGCLSSL

TRMT61B

71

Q9BVS5
APSGVIQLPLSSCSR

SEMA4G

496

Q9NTN9
ISGGESSLLPTRPTC

STON1

116

Q9Y6Q2
ISCLTGPTKRSTLAP

SLC5A5

546

Q92911
SLSTVPPGCINLSGA

SAGE1

691

Q9NXZ1
GSTTPLEACLTPASL

SERTAD2

121

Q14140
VSPPPASSSSECSLI

GTF2H2

236

Q13888
TLTRSVDVPSIPSCG

STPG2

81

Q8N412
TTPCSSAIINPLSTA

RIPK2

411

O43353
VVSASLISPASTPSC

TNKS

971

O95271
SLSRSAVLQPGCPSV

VPS18

11

Q9P253
ISPCLLESSSQLPVS

SLCO1C1

151

Q9NYB5
LGCVPTIPATASAAS

SORBS1

186

Q9BX66
ASQPACSPSGILSTV

TBC1D16

176

Q8TBP0
TFVLSCVATGSPVPT

ROBO1

471

Q9Y6N7
GATSTEVSLCAPPTA

TGM5

96

O43548
SSGSAVSCSTIPPEL

RIOK2

486

Q9BVS4
CSLGSVLLSPTSTAP

TSHZ3

801

Q63HK5
AATPSSSLPCTLIAL

YY1AP1

41

Q9H869
TSLASCVPASSVLPT

WDR62

1171

O43379
IPLCLPSTSDSVATL

HIVEP2

1421

P31629
TCLSLTPSTLPEEAT

TIMD4

196

Q96H15
SLNCSAAGTPTPSLV

MXRA5

2561

Q9NR99
SPSCSLSLLAPAEGL

NACAD

231

O15069